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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Tcf3

Z-value: 1.29

Motif logo

Transcription factors associated with Tcf3

Gene Symbol Gene ID Gene Info
ENSMUSG00000020167.15 Tcf3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Tcf3mm39_v1_chr10_-_80269436_802694880.326.1e-03Click!

Activity profile of Tcf3 motif

Sorted Z-values of Tcf3 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Tcf3

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr4_-_43523595 17.03 ENSMUST00000107914.10
tropomyosin 2, beta
chr4_-_43523745 16.68 ENSMUST00000150592.2
tropomyosin 2, beta
chr4_-_43523388 15.72 ENSMUST00000107913.10
ENSMUST00000030184.12
tropomyosin 2, beta
chr11_-_100036792 8.60 ENSMUST00000007317.8
keratin 19
chr8_+_46338498 7.56 ENSMUST00000034053.7
PDZ and LIM domain 3
chr1_+_75336965 7.43 ENSMUST00000027409.10
desmin
chr2_+_131028861 7.19 ENSMUST00000028804.15
ENSMUST00000079857.9
cell division cycle 25B
chr8_+_23629080 6.91 ENSMUST00000033947.15
ankyrin 1, erythroid
chr8_+_46338557 6.88 ENSMUST00000210422.2
PDZ and LIM domain 3
chr8_-_112417633 6.87 ENSMUST00000034435.7
chymotrypsinogen B1
chr16_+_57173456 6.75 ENSMUST00000159816.8
filamin A interacting protein 1-like
chr15_-_101268036 6.69 ENSMUST00000077196.6
keratin 80
chr2_-_28453374 6.47 ENSMUST00000028161.6
carboxyl ester lipase
chr7_+_142025575 6.29 ENSMUST00000038946.9
lymphocyte specific 1
chr7_+_142025817 6.27 ENSMUST00000105966.2
lymphocyte specific 1
chr6_-_41291634 5.91 ENSMUST00000064324.12
trypsin 5
chr6_+_30639217 5.79 ENSMUST00000031806.10
carboxypeptidase A1, pancreatic
chr6_+_17307639 5.67 ENSMUST00000115453.2
caveolin 1, caveolae protein
chr7_+_140659672 5.62 ENSMUST00000066873.5
ENSMUST00000163041.2
plakophilin 3
chr8_+_23629046 5.41 ENSMUST00000121075.8
ankyrin 1, erythroid
chr7_+_141995545 5.29 ENSMUST00000105971.8
ENSMUST00000145287.8
troponin I, skeletal, fast 2
chr6_+_17307272 5.25 ENSMUST00000115454.2
caveolin 1, caveolae protein
chr17_+_75485791 5.19 ENSMUST00000135447.8
ENSMUST00000112516.8
latent transforming growth factor beta binding protein 1
chr11_+_98555167 5.18 ENSMUST00000017348.3
gasdermin A
chr8_-_106660470 5.16 ENSMUST00000034368.8
chymotrypsin-like
chr16_-_56706494 4.68 ENSMUST00000023435.6
transmembrane protein 45a
chr7_-_105131407 4.55 ENSMUST00000047040.4
caveolae associated 3
chr3_+_106393348 4.43 ENSMUST00000183271.2
DENN/MADD domain containing 2D
chr1_+_135252508 4.43 ENSMUST00000059352.3
leiomodin 1 (smooth muscle)
chr14_-_70415117 4.42 ENSMUST00000022681.11
PDZ and LIM domain 2
chr17_+_75485906 4.34 ENSMUST00000112514.2
latent transforming growth factor beta binding protein 1
chr7_+_141996067 4.32 ENSMUST00000149529.8
troponin I, skeletal, fast 2
chr3_-_20329823 4.25 ENSMUST00000011607.6
carboxypeptidase B1 (tissue)
chr19_+_5118103 4.25 ENSMUST00000070630.8
CD248 antigen, endosialin
chr9_+_21249118 4.22 ENSMUST00000034697.8
solute carrier family 44, member 2
chr15_-_101759212 4.14 ENSMUST00000023790.5
keratin 1
chr13_-_111945499 4.12 ENSMUST00000109267.9
mitogen-activated protein kinase kinase kinase 1
chr14_+_30601157 4.11 ENSMUST00000040715.8
musculoskeletal, embryonic nuclear protein 1
chr13_-_55676334 4.04 ENSMUST00000047877.5
docking protein 3
chr4_+_42255693 4.01 ENSMUST00000178864.3
chemokine (C-C motif) ligand 21B (leucine)
chr2_-_125348305 4.00 ENSMUST00000028633.13
fibrillin 1
chrX_-_111608339 3.99 ENSMUST00000039887.4
premature ovarian failure 1B
chr4_+_41903610 3.91 ENSMUST00000098128.4
chemokine (C-C motif) ligand 21D
chr15_-_101588714 3.88 ENSMUST00000023786.7
keratin 6B
chr4_+_42114817 3.87 ENSMUST00000098123.4
predicted gene 13304
chr6_-_68609426 3.86 ENSMUST00000103328.3
immunoglobulin kappa variable 10-96
chr11_+_69856222 3.85 ENSMUST00000018713.13
claudin 7
chr15_-_101621332 3.81 ENSMUST00000023709.7
keratin 5
chr12_+_51640097 3.72 ENSMUST00000164782.10
ENSMUST00000085412.7
cochlin
chr6_-_69792108 3.71 ENSMUST00000103367.3
immunoglobulin kappa variable 12-44
chr2_-_91854844 3.69 ENSMUST00000028663.5
cAMP responsive element binding protein 3-like 1
chr1_+_177270101 3.69 ENSMUST00000194319.2
zinc finger and BTB domain containing 18
chr12_-_114672701 3.62 ENSMUST00000103505.3
ENSMUST00000193855.2
immunoglobulin heavy variable V1-19
chr1_-_79649683 3.61 ENSMUST00000162342.8
adaptor-related protein complex AP-1, sigma 3
chr4_+_97665992 3.59 ENSMUST00000107062.9
ENSMUST00000052018.12
ENSMUST00000107057.8
nuclear factor I/A
chr17_-_36014892 3.56 ENSMUST00000097333.10
ENSMUST00000003628.13
discoidin domain receptor family, member 1
chr12_-_114901026 3.53 ENSMUST00000103516.2
ENSMUST00000191868.2
immunoglobulin heavy variable V1-42
chr19_-_57185988 3.50 ENSMUST00000099294.9
actin-binding LIM protein 1
chr3_-_100396635 3.47 ENSMUST00000061455.9
terminal nucleotidyltransferase 5C
chr11_-_3477916 3.45 ENSMUST00000020718.10
smoothelin
chr5_+_21748523 3.44 ENSMUST00000035651.6
leucine rich repeat containing 17
chr7_-_126224848 3.41 ENSMUST00000032961.4
nuclear protein transcription regulator 1
chr6_-_68713748 3.40 ENSMUST00000183936.2
ENSMUST00000196863.2
immunoglobulin kappa chain variable 19-93
chr2_-_35322581 3.40 ENSMUST00000079424.11
glycoprotein galactosyltransferase alpha 1, 3
chr9_-_31824758 3.34 ENSMUST00000116615.5
BarH-like homeobox 2
chr16_-_19019100 3.33 ENSMUST00000103749.3
immunoglobulin lambda constant 2
chr11_+_115790768 3.32 ENSMUST00000152171.8
small integral membrane protein 5
chr4_+_140737955 3.31 ENSMUST00000071977.9
microfibrillar-associated protein 2
chr1_+_78286946 3.30 ENSMUST00000036172.10
sphingosine-1-phosphate phosphatase 2
chrX_-_47551990 3.25 ENSMUST00000033429.9
ENSMUST00000140486.2
E74-like factor 4 (ets domain transcription factor)
chr7_-_44180700 3.25 ENSMUST00000205506.2
Spi-B transcription factor (Spi-1/PU.1 related)
chr3_+_89344006 3.25 ENSMUST00000038942.10
ENSMUST00000130858.8
ENSMUST00000146630.8
ENSMUST00000145753.2
pre B cell leukemia transcription factor interacting protein 1
chr7_+_44866635 3.14 ENSMUST00000097216.5
ENSMUST00000209343.2
ENSMUST00000209678.2
TEA domain family member 2
chr10_+_128745214 3.11 ENSMUST00000220308.2
CD63 antigen
chr8_-_106198112 3.09 ENSMUST00000014990.13
tubulin polymerization-promoting protein family member 3
chr15_+_78810919 3.09 ENSMUST00000089377.6
lectin, galactose binding, soluble 1
chrX_+_100492684 3.08 ENSMUST00000033674.6
integrin beta 1 binding protein 2
chr13_-_60325170 3.06 ENSMUST00000065086.6
growth arrest specific 1
chr5_-_98178811 3.02 ENSMUST00000031281.14
anthrax toxin receptor 2
chr17_-_48739874 2.99 ENSMUST00000046549.5
apolipoprotein B mRNA editing enzyme, catalytic polypeptide 2
chr5_+_17779721 2.96 ENSMUST00000169603.2
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr6_-_68812291 2.96 ENSMUST00000199143.5
ENSMUST00000103335.3
immunoglobulin kappa chain variable 12-89
chr2_-_118593087 2.87 ENSMUST00000059997.9
coiled-coil domain containing 9B
chr7_-_89176294 2.86 ENSMUST00000207932.2
protease, serine 23
chr2_-_152775122 2.86 ENSMUST00000099200.3
forkhead box S1
chr8_+_3715747 2.86 ENSMUST00000014118.4
mast cell expressed membrane protein 1
chr5_-_113968483 2.84 ENSMUST00000100874.6
selectin, platelet (p-selectin) ligand
chr2_+_49677688 2.81 ENSMUST00000028103.13
LY6/PLAUR domain containing 6B
chrX_-_56384089 2.80 ENSMUST00000033468.11
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr4_+_129181407 2.80 ENSMUST00000102599.4
syncoilin
chr19_-_11243530 2.79 ENSMUST00000169159.3
membrane-spanning 4-domains, subfamily A, member 1
chr6_-_134609350 2.79 ENSMUST00000047443.5
MANSC domain containing 1
chr12_-_115299134 2.78 ENSMUST00000195359.6
ENSMUST00000103530.3
immunoglobulin heavy variable V1-59
chr7_-_109322993 2.78 ENSMUST00000106735.9
ENSMUST00000033334.5
cDNA sequence BC051019
chr7_+_19024994 2.74 ENSMUST00000108468.5
reticulon 2 (Z-band associated protein)
chr6_-_67919524 2.74 ENSMUST00000196768.2
immunoglobulin kappa chain variable 9-124
chr11_-_46057224 2.73 ENSMUST00000020679.3
NIPA-like domain containing 4
chr3_+_146558114 2.71 ENSMUST00000170055.8
ENSMUST00000037942.11
tubulin tyrosine ligase-like family, member 7
chr3_+_95496239 2.71 ENSMUST00000177390.8
ENSMUST00000060323.12
ENSMUST00000098861.11
golgi phosphoprotein 3-like
chr17_+_35413415 2.69 ENSMUST00000025262.6
ENSMUST00000173600.2
lymphotoxin B
chr3_+_95496270 2.69 ENSMUST00000176674.8
ENSMUST00000177389.8
ENSMUST00000176755.8
ENSMUST00000177399.2
golgi phosphoprotein 3-like
chr12_-_114646685 2.68 ENSMUST00000194350.6
ENSMUST00000103504.3
immunoglobulin heavy variable V1-18
chr12_-_115172211 2.68 ENSMUST00000103526.3
immunoglobulin heavy variable 1-55
chr15_+_99489018 2.67 ENSMUST00000229728.2
ENSMUST00000231163.2
aquaporin 5
chr3_-_151971391 2.65 ENSMUST00000199470.5
ENSMUST00000200589.5
nexilin
chr19_-_57185928 2.63 ENSMUST00000111544.8
actin-binding LIM protein 1
chr4_-_141325517 2.63 ENSMUST00000131317.8
ENSMUST00000006381.11
ENSMUST00000129602.8
filamin binding LIM protein 1
chr8_-_123425805 2.63 ENSMUST00000127984.9
CBFA2/RUNX1 translocation partner 3
chr12_+_9624437 2.61 ENSMUST00000057021.9
odd-skipped related transcription factor 1
chr11_-_102255999 2.60 ENSMUST00000006749.10
solute carrier family 4 (anion exchanger), member 1
chr7_-_131756447 2.58 ENSMUST00000033149.5
carboxypeptidase X 2 (M14 family)
chr17_+_75772475 2.57 ENSMUST00000095204.6
RAS, guanyl releasing protein 3
chr19_-_45548942 2.56 ENSMUST00000026239.7
polymerase (DNA directed), lambda
chr19_-_57185861 2.55 ENSMUST00000111550.8
actin-binding LIM protein 1
chr2_+_174602412 2.54 ENSMUST00000029030.9
endothelin 3
chr9_-_58065800 2.53 ENSMUST00000168864.4
immunoglobulin superfamily containing leucine-rich repeat
chr4_+_141148068 2.52 ENSMUST00000102486.5
heat shock protein family, member 7 (cardiovascular)
chr12_-_114878652 2.52 ENSMUST00000103515.2
immunoglobulin heavy variable 1-39
chr19_-_57185808 2.52 ENSMUST00000111546.8
actin-binding LIM protein 1
chr8_+_23629173 2.49 ENSMUST00000174435.2
ankyrin 1, erythroid
chrX_-_72478938 2.47 ENSMUST00000033738.8
three prime repair exonuclease 2
chr19_+_6952580 2.45 ENSMUST00000237084.2
ENSMUST00000236218.2
ENSMUST00000237235.2
protein phosphatase 1, regulatory inhibitor subunit 14B
chr4_-_130068902 2.44 ENSMUST00000105998.8
tubulointerstitial nephritis antigen-like 1
chr19_-_6065181 2.44 ENSMUST00000236537.2
ENSMUST00000025891.11
calpain 1
chr4_-_133600308 2.42 ENSMUST00000137486.3
ribosomal protein S6 kinase polypeptide 1
chr10_-_78554104 2.42 ENSMUST00000005488.9
caspase 14
chr6_-_69741999 2.42 ENSMUST00000103365.3
immunoglobulin kappa variable 12-46
chr11_+_70548622 2.40 ENSMUST00000170716.8
enolase 3, beta muscle
chr6_+_70648743 2.39 ENSMUST00000103401.3
immunoglobulin kappa variable 3-4
chr6_+_41331039 2.36 ENSMUST00000072103.7
trypsin 10
chr2_+_103800459 2.31 ENSMUST00000111143.8
ENSMUST00000138815.2
LIM domain only 2
chr2_+_103254465 2.31 ENSMUST00000171693.8
E74-like factor 5
chr3_-_75177378 2.30 ENSMUST00000039047.5
serine (or cysteine) peptidase inhibitor, clade I, member 2
chr5_-_98178834 2.27 ENSMUST00000199088.2
anthrax toxin receptor 2
chr11_+_96820091 2.25 ENSMUST00000054311.6
ENSMUST00000107636.4
proline rich 15-like
chr5_+_123214332 2.24 ENSMUST00000067505.15
ENSMUST00000111619.10
ENSMUST00000160344.2
transmembrane protein 120B
chr17_+_75772567 2.24 ENSMUST00000234660.2
RAS, guanyl releasing protein 3
chr8_+_72050292 2.22 ENSMUST00000143662.8
niban apoptosis regulator 3
chr15_-_78657640 2.22 ENSMUST00000018313.6
MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr7_+_19144950 2.21 ENSMUST00000208710.2
ENSMUST00000003643.3
creatine kinase, muscle
chr11_+_63019799 2.21 ENSMUST00000108702.8
peripheral myelin protein 22
chr1_-_171061838 2.21 ENSMUST00000193973.2
Fc receptor, IgE, high affinity I, gamma polypeptide
chr6_-_69835868 2.19 ENSMUST00000103369.2
immunoglobulin kappa chain variable 12-41
chr10_-_120037464 2.17 ENSMUST00000020448.11
interleukin-1 receptor-associated kinase 3
chr15_-_77527470 2.17 ENSMUST00000181154.2
ENSMUST00000180949.8
ENSMUST00000166623.10
apolipoprotein L 11b
chr15_-_36598263 2.16 ENSMUST00000155116.2
poly(A) binding protein, cytoplasmic 1
chr14_+_26760898 2.15 ENSMUST00000035336.5
interleukin 17 receptor D
chr1_-_192880260 2.15 ENSMUST00000161367.2
TRAF3 interacting protein 3
chr17_-_71309012 2.14 ENSMUST00000128179.2
ENSMUST00000150456.2
ENSMUST00000233357.2
ENSMUST00000233417.2
myosin, light chain 12A, regulatory, non-sarcomeric
predicted gene, 49909
chr7_-_80037153 2.13 ENSMUST00000206728.2
feline sarcoma oncogene
chr2_+_103800553 2.12 ENSMUST00000111140.3
ENSMUST00000111139.3
LIM domain only 2
chr19_+_6952319 2.11 ENSMUST00000070850.8
protein phosphatase 1, regulatory inhibitor subunit 14B
chr7_+_3339077 2.11 ENSMUST00000203566.3
myeloid-associated differentiation marker
chr7_+_3339059 2.11 ENSMUST00000096744.8
myeloid-associated differentiation marker
chr10_-_128579879 2.10 ENSMUST00000026414.9
diacylglycerol kinase, alpha
chr9_-_105837842 2.09 ENSMUST00000190193.8
ENSMUST00000165165.3
collagen, type VI, alpha 5
chr19_+_8975249 2.08 ENSMUST00000236390.2
AHNAK nucleoprotein (desmoyokin)
chr1_-_153061758 2.08 ENSMUST00000185356.7
laminin, gamma 2
chr7_+_27770655 2.07 ENSMUST00000138392.8
ENSMUST00000076648.8
Fc fragment of IgG binding protein
chr3_-_151871867 2.06 ENSMUST00000046614.10
GIPC PDZ domain containing family, member 2
chr15_-_77653979 2.04 ENSMUST00000229259.2
myosin, heavy polypeptide 9, non-muscle
chr11_-_101357046 2.03 ENSMUST00000040430.8
vesicle amine transport 1
chr2_-_113883285 2.03 ENSMUST00000090269.7
actin, alpha, cardiac muscle 1
chr12_-_114451189 2.03 ENSMUST00000103493.3
immunoglobulin heavy variable 1-4
chr15_+_61857226 2.02 ENSMUST00000161976.8
ENSMUST00000022971.8
myelocytomatosis oncogene
chr2_+_125876566 2.02 ENSMUST00000064794.14
fibroblast growth factor 7
chr1_+_135060431 2.02 ENSMUST00000187985.7
ENSMUST00000049449.11
protein tyrosine phosphatase, non-receptor type 7
chr3_-_151541603 2.01 ENSMUST00000106126.2
prostaglandin F receptor
chr9_-_107863062 2.01 ENSMUST00000048568.6
inka box actin regulator 1
chr6_-_124715618 2.01 ENSMUST00000171549.9
protein tyrosine phosphatase, non-receptor type 6
chr2_-_93164812 1.99 ENSMUST00000111265.9
tetraspanin 18
chr5_+_99002293 1.98 ENSMUST00000031278.6
ENSMUST00000200388.2
bone morphogenetic protein 3
chr6_-_124715560 1.98 ENSMUST00000004377.15
protein tyrosine phosphatase, non-receptor type 6
chr6_-_52222776 1.97 ENSMUST00000048026.10
homeobox A11
chr15_+_102927366 1.96 ENSMUST00000165375.3
homeobox C4
chr11_-_7163897 1.96 ENSMUST00000020702.11
ENSMUST00000135887.3
insulin-like growth factor binding protein 3
chr8_+_83891972 1.96 ENSMUST00000034145.11
TBC1 domain family, member 9
chr6_-_148345834 1.94 ENSMUST00000060095.15
ENSMUST00000100772.10
transmembrane and tetratricopeptide repeat containing 1
chr6_+_67873135 1.94 ENSMUST00000103310.3
immunoglobulin kappa variable 14-126
chr3_+_89090437 1.94 ENSMUST00000140473.2
ENSMUST00000041913.13
family with sequence similarity 189, member B
chr13_+_37529184 1.94 ENSMUST00000021860.7
lymphocyte antigen 86
chr8_+_36561982 1.93 ENSMUST00000110492.2
PEAK1 related kinase activating pseudokinase 1
chr6_+_112436466 1.93 ENSMUST00000075477.8
caveolin 3
chr11_+_11636213 1.92 ENSMUST00000076700.11
ENSMUST00000048122.13
IKAROS family zinc finger 1
chr11_+_115790951 1.92 ENSMUST00000142089.2
ENSMUST00000131566.2
small integral membrane protein 5
chrX_-_144131890 1.91 ENSMUST00000040084.10
ENSMUST00000123443.2
lipoma HMGIC fusion partner-like 1
chr12_-_115884332 1.91 ENSMUST00000103548.3
immunoglobulin heavy variable 1-81
chr4_-_133694607 1.91 ENSMUST00000105893.8
high mobility group nucleosomal binding domain 2
chr10_+_75729237 1.90 ENSMUST00000009236.6
ENSMUST00000217811.2
Der1-like domain family, member 3
chr10_+_126899468 1.90 ENSMUST00000120226.8
ENSMUST00000133115.8
cyclin-dependent kinase 4
chr17_-_73706284 1.89 ENSMUST00000095208.4
calpain 13
chr5_-_134643805 1.89 ENSMUST00000202085.2
ENSMUST00000036362.13
ENSMUST00000077636.8
linker for activation of T cells family, member 2
chr9_+_37439367 1.88 ENSMUST00000002011.14
endothelial cell-specific adhesion molecule
chr6_-_3494587 1.88 ENSMUST00000049985.15
HEPACAM family member 2
chr6_-_41354538 1.88 ENSMUST00000096003.7
protease, serine 3
chr19_+_53128901 1.88 ENSMUST00000235754.2
ENSMUST00000237301.2
ENSMUST00000238130.2
adducin 3 (gamma)
chr6_-_87473260 1.88 ENSMUST00000101197.9
Rho GTPase activating protein 25
chr11_-_100288566 1.87 ENSMUST00000001592.15
ENSMUST00000107403.2
junction plakoglobin
chr13_-_56326511 1.86 ENSMUST00000169652.3
TRAF-interacting protein with forkhead-associated domain, family member B
chr7_+_126811831 1.86 ENSMUST00000127710.3
myosin light chain, phosphorylatable, fast skeletal muscle

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 12.6 GO:1900085 negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609)
1.2 7.5 GO:0002159 desmosome assembly(GO:0002159)
1.2 3.6 GO:0061033 secretion by lung epithelial cell involved in lung growth(GO:0061033)
1.2 3.5 GO:0098583 mastication(GO:0071626) learned vocalization behavior(GO:0098583)
1.1 4.5 GO:1901003 negative regulation of fermentation(GO:1901003)
1.1 5.5 GO:0072186 metanephric cap development(GO:0072185) metanephric cap morphogenesis(GO:0072186) metanephric cap mesenchymal cell proliferation involved in metanephros development(GO:0090094)
1.0 3.1 GO:0034117 erythrocyte aggregation(GO:0034117) regulation of erythrocyte aggregation(GO:0034118)
1.0 4.0 GO:0035582 sequestering of BMP in extracellular matrix(GO:0035582)
1.0 3.0 GO:0003350 pulmonary myocardium development(GO:0003350)
0.9 2.8 GO:0033082 regulation of extrathymic T cell differentiation(GO:0033082)
0.9 3.4 GO:0042335 cuticle development(GO:0042335)
0.8 3.4 GO:0042125 protein glycosylation at cell surface(GO:0033575) protein galactosylation at cell surface(GO:0033580) protein galactosylation(GO:0042125)
0.8 7.2 GO:0007144 female meiosis I(GO:0007144)
0.7 3.7 GO:0070278 extracellular matrix constituent secretion(GO:0070278)
0.7 2.9 GO:0032765 positive regulation of mast cell cytokine production(GO:0032765)
0.7 5.8 GO:0033277 abortive mitotic cell cycle(GO:0033277)
0.7 1.4 GO:0003032 detection of oxygen(GO:0003032)
0.7 2.0 GO:1903465 motogenic signaling involved in postnatal olfactory bulb interneuron migration(GO:0021837) positive regulation of mitotic cell cycle DNA replication(GO:1903465)
0.6 1.9 GO:0045660 positive regulation of neutrophil differentiation(GO:0045660)
0.6 0.6 GO:0060715 syncytiotrophoblast cell differentiation involved in labyrinthine layer development(GO:0060715)
0.6 4.1 GO:0001712 ectodermal cell fate commitment(GO:0001712)
0.6 1.8 GO:0002017 regulation of blood volume by renal aldosterone(GO:0002017)
0.6 1.7 GO:0060032 floor plate formation(GO:0021508) notochord regression(GO:0060032)
0.6 2.8 GO:0050902 leukocyte adhesive activation(GO:0050902)
0.6 1.7 GO:0002378 immunoglobulin biosynthetic process(GO:0002378)
0.6 1.7 GO:0072268 pattern specification involved in metanephros development(GO:0072268)
0.6 1.7 GO:0021682 nerve maturation(GO:0021682)
0.5 1.6 GO:0098903 membrane repolarization during action potential(GO:0086011) regulation of membrane repolarization during action potential(GO:0098903)
0.5 1.6 GO:2000402 negative regulation of lymphocyte migration(GO:2000402)
0.5 4.2 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.5 1.6 GO:1903904 negative regulation of establishment of T cell polarity(GO:1903904)
0.5 3.1 GO:2000680 regulation of rubidium ion transport(GO:2000680)
0.5 4.1 GO:1902732 positive regulation of chondrocyte proliferation(GO:1902732)
0.5 3.1 GO:0003100 regulation of systemic arterial blood pressure by endothelin(GO:0003100) vein smooth muscle contraction(GO:0014826)
0.5 2.0 GO:1903921 protein processing in phagocytic vesicle(GO:1900756) regulation of protein processing in phagocytic vesicle(GO:1903921) positive regulation of protein processing in phagocytic vesicle(GO:1903923)
0.5 1.5 GO:2000832 negative regulation of steroid hormone secretion(GO:2000832)
0.5 2.0 GO:0071798 response to prostaglandin D(GO:0071798) cellular response to prostaglandin D stimulus(GO:0071799)
0.5 4.4 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.5 6.3 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.5 1.4 GO:0097374 sensory neuron axon guidance(GO:0097374)
0.5 1.4 GO:0061193 taste bud development(GO:0061193)
0.4 3.6 GO:0042713 sperm ejaculation(GO:0042713)
0.4 1.8 GO:0060988 lipid tube assembly(GO:0060988)
0.4 5.7 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.4 3.9 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.4 3.4 GO:0048539 bone marrow development(GO:0048539)
0.4 2.6 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.4 3.8 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.4 1.3 GO:0002874 regulation of chronic inflammatory response to antigenic stimulus(GO:0002874)
0.4 1.2 GO:0051385 response to mineralocorticoid(GO:0051385)
0.4 1.2 GO:0010615 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244)
0.4 0.8 GO:0002572 pro-T cell differentiation(GO:0002572)
0.4 13.2 GO:0045109 intermediate filament organization(GO:0045109)
0.4 2.3 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.4 1.5 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.4 1.5 GO:0033088 negative regulation of immature T cell proliferation in thymus(GO:0033088)
0.4 1.8 GO:0070268 cornification(GO:0070268)
0.4 1.5 GO:0032972 regulation of muscle filament sliding speed(GO:0032972)
0.4 2.2 GO:0010936 negative regulation of macrophage cytokine production(GO:0010936)
0.4 7.8 GO:0046514 ceramide catabolic process(GO:0046514)
0.3 2.4 GO:0010288 response to lead ion(GO:0010288)
0.3 2.0 GO:0010637 negative regulation of mitochondrial fusion(GO:0010637)
0.3 5.4 GO:0048194 Golgi vesicle budding(GO:0048194)
0.3 1.0 GO:1900108 negative regulation of nodal signaling pathway(GO:1900108)
0.3 1.3 GO:2001137 positive regulation of endocytic recycling(GO:2001137)
0.3 3.3 GO:0001866 NK T cell proliferation(GO:0001866)
0.3 14.8 GO:0006779 porphyrin-containing compound biosynthetic process(GO:0006779)
0.3 1.9 GO:1904180 negative regulation of membrane depolarization(GO:1904180)
0.3 4.1 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.3 9.5 GO:0032967 positive regulation of collagen biosynthetic process(GO:0032967)
0.3 1.3 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.3 3.1 GO:0032224 positive regulation of synaptic transmission, cholinergic(GO:0032224)
0.3 1.6 GO:0061056 sclerotome development(GO:0061056)
0.3 2.2 GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.3 0.9 GO:0002426 immunoglobulin production in mucosal tissue(GO:0002426)
0.3 5.5 GO:0072189 ureter development(GO:0072189)
0.3 1.2 GO:0002036 regulation of L-glutamate transport(GO:0002036)
0.3 4.6 GO:0060033 anatomical structure regression(GO:0060033)
0.3 0.9 GO:0030327 prenylated protein catabolic process(GO:0030327)
0.3 0.8 GO:0072054 renal outer medulla development(GO:0072054) regulation of chromatin-mediated maintenance of transcription(GO:1904499) positive regulation of chromatin-mediated maintenance of transcription(GO:1904501) regulation of euchromatin binding(GO:1904793)
0.3 0.8 GO:2000451 positive regulation of CD8-positive, alpha-beta T cell extravasation(GO:2000451)
0.3 2.0 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.3 0.8 GO:1990426 homologous recombination-dependent replication fork processing(GO:1990426)
0.3 1.1 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.3 4.4 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.3 1.0 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.3 1.3 GO:0048069 eye pigmentation(GO:0048069)
0.3 2.6 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.2 0.7 GO:0002270 plasmacytoid dendritic cell activation(GO:0002270)
0.2 0.7 GO:0097065 anterior head development(GO:0097065) regulation of anterior head development(GO:2000742) positive regulation of anterior head development(GO:2000744)
0.2 2.7 GO:0015670 carbon dioxide transport(GO:0015670)
0.2 2.6 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.2 1.9 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.2 0.7 GO:0014735 regulation of muscle atrophy(GO:0014735) death-inducing signaling complex assembly(GO:0071550) negative regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902109)
0.2 3.7 GO:0048368 lateral mesoderm development(GO:0048368)
0.2 2.1 GO:0042637 catagen(GO:0042637)
0.2 34.5 GO:0006910 phagocytosis, recognition(GO:0006910)
0.2 1.1 GO:0038032 termination of G-protein coupled receptor signaling pathway(GO:0038032)
0.2 1.8 GO:0016554 cytidine to uridine editing(GO:0016554)
0.2 0.7 GO:1903334 positive regulation of protein folding(GO:1903334)
0.2 0.7 GO:0035638 patched ligand maturation(GO:0007225) signal maturation(GO:0035638)
0.2 1.3 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.2 1.5 GO:0044336 canonical Wnt signaling pathway involved in negative regulation of apoptotic process(GO:0044336)
0.2 0.9 GO:0090472 dibasic protein processing(GO:0090472)
0.2 1.7 GO:0010897 negative regulation of triglyceride catabolic process(GO:0010897)
0.2 10.1 GO:0003009 skeletal muscle contraction(GO:0003009)
0.2 1.5 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816)
0.2 2.7 GO:0018095 protein polyglutamylation(GO:0018095)
0.2 0.6 GO:0051305 chromosome movement towards spindle pole(GO:0051305)
0.2 0.6 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.2 1.8 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.2 2.0 GO:0030240 skeletal muscle thin filament assembly(GO:0030240)
0.2 3.9 GO:0032463 negative regulation of protein homooligomerization(GO:0032463)
0.2 3.6 GO:0016540 protein autoprocessing(GO:0016540)
0.2 0.8 GO:0098886 modification of dendritic spine(GO:0098886)
0.2 2.1 GO:0035878 nail development(GO:0035878)
0.2 3.4 GO:2000194 regulation of female gonad development(GO:2000194)
0.2 0.9 GO:2000584 regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000583) negative regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000584)
0.2 0.5 GO:0001698 gastrin-induced gastric acid secretion(GO:0001698)
0.2 2.0 GO:0060272 embryonic skeletal joint morphogenesis(GO:0060272)
0.2 2.7 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.2 0.5 GO:0070103 regulation of interleukin-6-mediated signaling pathway(GO:0070103)
0.2 8.1 GO:0060706 cell differentiation involved in embryonic placenta development(GO:0060706)
0.2 1.4 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.2 3.3 GO:0006670 sphingosine metabolic process(GO:0006670)
0.2 0.7 GO:1902202 regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.2 0.5 GO:0060676 ureteric bud formation(GO:0060676)
0.2 3.1 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.2 3.6 GO:0045103 intermediate filament-based process(GO:0045103)
0.2 2.6 GO:0033623 regulation of integrin activation(GO:0033623)
0.2 1.3 GO:0030035 microspike assembly(GO:0030035)
0.2 2.7 GO:0090308 regulation of methylation-dependent chromatin silencing(GO:0090308)
0.2 1.7 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
0.2 0.9 GO:0014043 negative regulation of neuron maturation(GO:0014043)
0.2 0.8 GO:0071921 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.2 3.2 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.2 1.1 GO:0006868 glutamine transport(GO:0006868)
0.2 0.6 GO:1901675 negative regulation of histone H3-K27 acetylation(GO:1901675)
0.2 0.3 GO:0060450 positive regulation of hindgut contraction(GO:0060450)
0.2 2.7 GO:0015693 magnesium ion transport(GO:0015693)
0.2 2.1 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.2 1.4 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.2 0.5 GO:0014908 myotube differentiation involved in skeletal muscle regeneration(GO:0014908)
0.2 0.8 GO:0034334 adherens junction maintenance(GO:0034334)
0.1 0.9 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.1 1.6 GO:0003344 pericardium morphogenesis(GO:0003344)
0.1 1.5 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.1 1.3 GO:0038203 TORC2 signaling(GO:0038203)
0.1 3.6 GO:0040034 regulation of development, heterochronic(GO:0040034)
0.1 2.1 GO:0090527 actin filament reorganization(GO:0090527)
0.1 0.3 GO:0060017 parathyroid gland development(GO:0060017)
0.1 1.5 GO:0045059 positive thymic T cell selection(GO:0045059)
0.1 2.5 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.1 1.6 GO:0045618 positive regulation of keratinocyte differentiation(GO:0045618)
0.1 2.3 GO:0043586 tongue development(GO:0043586)
0.1 0.9 GO:0070294 renal sodium ion absorption(GO:0070294)
0.1 1.3 GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
0.1 2.4 GO:0097205 renal filtration(GO:0097205)
0.1 0.5 GO:1901187 regulation of ephrin receptor signaling pathway(GO:1901187)
0.1 0.7 GO:0044727 DNA demethylation of male pronucleus(GO:0044727)
0.1 13.4 GO:0030032 lamellipodium assembly(GO:0030032)
0.1 3.2 GO:0061029 eyelid development in camera-type eye(GO:0061029)
0.1 2.3 GO:1904776 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.1 3.3 GO:0015701 bicarbonate transport(GO:0015701)
0.1 45.5 GO:0006936 muscle contraction(GO:0006936)
0.1 2.1 GO:0046339 phosphatidic acid biosynthetic process(GO:0006654) diacylglycerol metabolic process(GO:0046339)
0.1 0.2 GO:0021524 visceral motor neuron differentiation(GO:0021524) peripheral nervous system neuron axonogenesis(GO:0048936)
0.1 14.1 GO:0007586 digestion(GO:0007586)
0.1 1.6 GO:0006301 postreplication repair(GO:0006301)
0.1 0.2 GO:0001705 ectoderm formation(GO:0001705)
0.1 2.2 GO:0070831 basement membrane assembly(GO:0070831)
0.1 0.9 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.1 0.1 GO:2000137 negative regulation of cell proliferation involved in heart morphogenesis(GO:2000137)
0.1 1.1 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.1 2.2 GO:0032060 bleb assembly(GO:0032060)
0.1 0.3 GO:0021664 rhombomere formation(GO:0021594) rhombomere 3 formation(GO:0021660) rhombomere 5 morphogenesis(GO:0021664) rhombomere 5 formation(GO:0021666)
0.1 1.6 GO:0045586 regulation of gamma-delta T cell differentiation(GO:0045586) regulation of gamma-delta T cell activation(GO:0046643)
0.1 0.7 GO:0010669 epithelial structure maintenance(GO:0010669)
0.1 1.5 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.1 0.8 GO:0060482 lobar bronchus epithelium development(GO:0060481) lobar bronchus development(GO:0060482)
0.1 4.7 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.1 1.3 GO:0070296 sarcoplasmic reticulum calcium ion transport(GO:0070296)
0.1 1.5 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.1 3.6 GO:0031116 positive regulation of microtubule polymerization(GO:0031116)
0.1 1.6 GO:0015732 prostaglandin transport(GO:0015732)
0.1 3.3 GO:0030220 platelet formation(GO:0030220)
0.1 4.1 GO:0070830 bicellular tight junction assembly(GO:0070830)
0.1 1.3 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.1 1.1 GO:0051418 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.1 0.3 GO:0044849 estrous cycle(GO:0044849) regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.1 1.7 GO:0007263 nitric oxide mediated signal transduction(GO:0007263)
0.1 1.8 GO:0010831 positive regulation of myotube differentiation(GO:0010831)
0.1 1.2 GO:0032494 response to peptidoglycan(GO:0032494)
0.1 3.3 GO:0030225 macrophage differentiation(GO:0030225)
0.1 0.5 GO:0045075 interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
0.1 0.4 GO:0021564 vagus nerve development(GO:0021564)
0.1 0.7 GO:1902730 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.1 0.5 GO:2000210 positive regulation of anoikis(GO:2000210)
0.1 2.8 GO:0030835 negative regulation of actin filament depolymerization(GO:0030835)
0.1 3.5 GO:0000186 activation of MAPKK activity(GO:0000186)
0.1 0.5 GO:0098719 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.1 0.5 GO:0032202 telomere assembly(GO:0032202)
0.1 0.5 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.1 0.9 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.1 0.4 GO:0045657 positive regulation of monocyte differentiation(GO:0045657)
0.1 0.4 GO:0010766 negative regulation of sodium ion transport(GO:0010766)
0.1 2.4 GO:0010107 potassium ion import(GO:0010107)
0.1 0.2 GO:0021571 rhombomere 5 development(GO:0021571)
0.1 0.2 GO:0071733 transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
0.1 2.0 GO:0000731 DNA synthesis involved in DNA repair(GO:0000731)
0.1 0.3 GO:0002143 tRNA wobble position uridine thiolation(GO:0002143)
0.1 0.6 GO:0005513 detection of calcium ion(GO:0005513) activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.1 0.7 GO:0021527 spinal cord association neuron differentiation(GO:0021527)
0.1 0.5 GO:0031179 peptide modification(GO:0031179)
0.1 0.5 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.1 1.1 GO:0038092 nodal signaling pathway(GO:0038092)
0.1 13.6 GO:0007519 skeletal muscle tissue development(GO:0007519)
0.1 1.2 GO:0032897 negative regulation of viral transcription(GO:0032897)
0.1 2.4 GO:0035329 hippo signaling(GO:0035329)
0.1 2.6 GO:0031648 protein destabilization(GO:0031648)
0.1 0.1 GO:0033686 positive regulation of gonadotropin secretion(GO:0032278) regulation of luteinizing hormone secretion(GO:0033684) positive regulation of luteinizing hormone secretion(GO:0033686)
0.1 0.5 GO:0000707 meiotic DNA recombinase assembly(GO:0000707) strand invasion(GO:0042148)
0.1 0.4 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.1 0.2 GO:0001830 trophectodermal cell fate commitment(GO:0001830)
0.1 0.9 GO:1903392 negative regulation of focal adhesion assembly(GO:0051895) negative regulation of adherens junction organization(GO:1903392)
0.1 1.0 GO:0002693 positive regulation of cellular extravasation(GO:0002693)
0.1 0.6 GO:0021516 dorsal spinal cord development(GO:0021516)
0.1 0.6 GO:0061032 visceral serous pericardium development(GO:0061032)
0.1 0.4 GO:0034134 toll-like receptor 2 signaling pathway(GO:0034134)
0.1 1.4 GO:0045214 sarcomere organization(GO:0045214)
0.1 1.2 GO:0071548 response to dexamethasone(GO:0071548) cellular response to dexamethasone stimulus(GO:0071549)
0.1 13.3 GO:0002377 immunoglobulin production(GO:0002377)
0.1 1.2 GO:0030574 collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
0.1 0.2 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.1 0.3 GO:0060923 cardiac muscle cell fate commitment(GO:0060923)
0.1 0.3 GO:2000399 negative regulation of T cell differentiation in thymus(GO:0033085) negative regulation of thymocyte aggregation(GO:2000399)
0.1 0.6 GO:0014850 response to muscle activity(GO:0014850)
0.1 0.4 GO:0043619 regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0043619)
0.1 0.3 GO:1902962 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.1 1.9 GO:0040018 positive regulation of multicellular organism growth(GO:0040018)
0.0 0.2 GO:0046601 positive regulation of centriole replication(GO:0046601)
0.0 0.2 GO:0045077 negative regulation of interferon-gamma biosynthetic process(GO:0045077)
0.0 0.4 GO:0008228 opsonization(GO:0008228)
0.0 0.5 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 1.5 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.0 1.8 GO:0046785 microtubule polymerization(GO:0046785)
0.0 0.2 GO:0032298 positive regulation of DNA-dependent DNA replication initiation(GO:0032298)
0.0 1.4 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0 0.3 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.0 1.0 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.2 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.0 0.6 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.0 0.3 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.1 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
0.0 0.9 GO:0051497 negative regulation of stress fiber assembly(GO:0051497)
0.0 0.5 GO:0048747 muscle fiber development(GO:0048747)
0.0 1.0 GO:0033599 regulation of mammary gland epithelial cell proliferation(GO:0033599)
0.0 0.4 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.0 1.8 GO:1901998 toxin transport(GO:1901998)
0.0 0.6 GO:0022011 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.0 2.1 GO:0007569 cell aging(GO:0007569)
0.0 0.3 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0 2.3 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.0 0.1 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.0 0.1 GO:0003199 heart valve formation(GO:0003188) endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
0.0 0.2 GO:0072386 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.0 1.1 GO:0002279 mast cell activation involved in immune response(GO:0002279) mast cell mediated immunity(GO:0002448) mast cell degranulation(GO:0043303)
0.0 0.6 GO:0034142 toll-like receptor 4 signaling pathway(GO:0034142)
0.0 1.0 GO:0000154 rRNA modification(GO:0000154)
0.0 0.1 GO:0006713 glucocorticoid catabolic process(GO:0006713)
0.0 1.4 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.2 GO:1902187 negative regulation of viral release from host cell(GO:1902187)
0.0 3.7 GO:0045089 positive regulation of innate immune response(GO:0045089)
0.0 0.6 GO:0001958 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0 0.1 GO:1904690 regulation of cap-independent translational initiation(GO:1903677) positive regulation of cap-independent translational initiation(GO:1903679) regulation of cytoplasmic translational initiation(GO:1904688) positive regulation of cytoplasmic translational initiation(GO:1904690)
0.0 0.7 GO:0045022 early endosome to late endosome transport(GO:0045022)
0.0 0.1 GO:0008295 spermidine biosynthetic process(GO:0008295)
0.0 0.3 GO:0043496 regulation of protein homodimerization activity(GO:0043496)
0.0 0.3 GO:0007379 segment specification(GO:0007379)
0.0 1.2 GO:0071806 intracellular protein transmembrane transport(GO:0065002) protein transmembrane transport(GO:0071806)
0.0 0.2 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.2 GO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236)
0.0 0.3 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.0 0.1 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.0 0.2 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.1 GO:0019372 lipoxygenase pathway(GO:0019372)
0.0 0.3 GO:0042118 endothelial cell activation(GO:0042118)
0.0 1.7 GO:0019827 stem cell population maintenance(GO:0019827)
0.0 1.7 GO:0060606 neural tube closure(GO:0001843) tube closure(GO:0060606)
0.0 0.1 GO:0035269 protein O-linked mannosylation(GO:0035269)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
3.3 49.4 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
3.2 9.5 GO:0038045 large latent transforming growth factor-beta complex(GO:0038045)
1.3 1.3 GO:0031095 platelet dense tubular network membrane(GO:0031095)
1.2 3.6 GO:0032998 Fc receptor complex(GO:0032997) Fc-epsilon receptor I complex(GO:0032998)
1.1 5.6 GO:0005914 spot adherens junction(GO:0005914)
1.0 3.1 GO:0031904 endosome lumen(GO:0031904)
1.0 8.6 GO:1990357 terminal web(GO:1990357)
0.9 3.7 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.8 14.9 GO:0005861 troponin complex(GO:0005861)
0.7 12.6 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.7 7.8 GO:0045098 type III intermediate filament(GO:0045098)
0.7 2.1 GO:0005607 laminin-2 complex(GO:0005607)
0.7 2.7 GO:0014802 terminal cisterna(GO:0014802)
0.7 2.0 GO:0042643 actomyosin, actin portion(GO:0042643)
0.6 7.3 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.6 2.4 GO:0034667 integrin alpha3-beta1 complex(GO:0034667)
0.5 3.2 GO:0097149 centralspindlin complex(GO:0097149)
0.5 7.3 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.5 13.3 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.4 2.0 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.4 1.6 GO:0060171 stereocilium membrane(GO:0060171)
0.4 16.2 GO:0045095 keratin filament(GO:0045095)
0.4 1.4 GO:0036284 tubulobulbar complex(GO:0036284)
0.3 1.7 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.3 7.5 GO:0005865 striated muscle thin filament(GO:0005865)
0.3 2.4 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.3 2.0 GO:0097513 myosin II filament(GO:0097513)
0.3 34.9 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.3 1.5 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.2 3.0 GO:0016011 dystroglycan complex(GO:0016011)
0.2 2.7 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.2 4.8 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.2 3.1 GO:0097427 microtubule bundle(GO:0097427)
0.2 1.4 GO:0005663 DNA replication factor C complex(GO:0005663)
0.2 2.5 GO:0097451 glial limiting end-foot(GO:0097451)
0.2 1.8 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.2 3.5 GO:0043034 costamere(GO:0043034)
0.2 2.8 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.2 1.3 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.2 24.8 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.2 2.4 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.2 6.5 GO:0042588 zymogen granule(GO:0042588)
0.2 1.1 GO:0008274 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.2 27.6 GO:0030018 Z disc(GO:0030018)
0.1 2.7 GO:0031674 I band(GO:0031674)
0.1 1.7 GO:0097542 ciliary tip(GO:0097542)
0.1 2.1 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 4.0 GO:0030057 desmosome(GO:0030057)
0.1 5.3 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 4.0 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 11.1 GO:0031985 Golgi cisterna(GO:0031985)
0.1 1.6 GO:0016589 NURF complex(GO:0016589)
0.1 1.0 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.1 0.6 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.1 1.0 GO:0030478 actin cap(GO:0030478)
0.1 0.7 GO:0070695 FHF complex(GO:0070695)
0.1 1.1 GO:0035102 PRC1 complex(GO:0035102)
0.1 1.9 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.1 0.8 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.1 6.0 GO:0005720 nuclear heterochromatin(GO:0005720)
0.1 2.1 GO:0030056 hemidesmosome(GO:0030056)
0.1 0.7 GO:0001940 male pronucleus(GO:0001940)
0.1 1.6 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.1 1.6 GO:0044232 organelle membrane contact site(GO:0044232)
0.1 5.4 GO:0045171 intercellular bridge(GO:0045171)
0.1 1.3 GO:0031932 TORC2 complex(GO:0031932)
0.1 0.9 GO:0044294 dendritic growth cone(GO:0044294)
0.1 0.5 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.1 1.5 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.1 3.1 GO:0005719 nuclear euchromatin(GO:0005719)
0.1 1.3 GO:0005721 pericentric heterochromatin(GO:0005721)
0.1 2.8 GO:0009925 basal plasma membrane(GO:0009925)
0.1 1.5 GO:0043218 compact myelin(GO:0043218)
0.1 4.4 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 0.8 GO:0008278 cohesin complex(GO:0008278)
0.1 1.1 GO:0031672 A band(GO:0031672)
0.1 2.3 GO:0044295 axonal growth cone(GO:0044295)
0.1 0.4 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.1 0.3 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.1 2.1 GO:0005581 collagen trimer(GO:0005581)
0.1 0.5 GO:0061574 ASAP complex(GO:0061574)
0.1 0.6 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 6.9 GO:0000922 spindle pole(GO:0000922)
0.0 2.5 GO:0016235 aggresome(GO:0016235)
0.0 0.6 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 5.3 GO:0030863 cortical cytoskeleton(GO:0030863)
0.0 2.2 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.2 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.0 1.8 GO:0031941 filamentous actin(GO:0031941)
0.0 4.9 GO:0016605 PML body(GO:0016605)
0.0 0.4 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.7 GO:0036038 MKS complex(GO:0036038)
0.0 1.0 GO:0005605 basal lamina(GO:0005605)
0.0 1.0 GO:0097440 apical dendrite(GO:0097440)
0.0 0.3 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.0 0.4 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.4 GO:0005614 interstitial matrix(GO:0005614)
0.0 5.0 GO:0005923 bicellular tight junction(GO:0005923)
0.0 4.7 GO:0032993 protein-DNA complex(GO:0032993)
0.0 1.3 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 0.4 GO:0034709 methylosome(GO:0034709)
0.0 0.8 GO:0043296 apical junction complex(GO:0043296)
0.0 3.3 GO:0030027 lamellipodium(GO:0030027)
0.0 0.1 GO:0000938 GARP complex(GO:0000938)
0.0 0.2 GO:0033268 node of Ranvier(GO:0033268)
0.0 0.1 GO:0045180 basal cortex(GO:0045180)
0.0 4.0 GO:0001650 fibrillar center(GO:0001650)
0.0 47.3 GO:0005615 extracellular space(GO:0005615)
0.0 0.5 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 1.3 GO:0005902 microvillus(GO:0005902)
0.0 1.6 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 3.5 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 5.0 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 1.2 GO:0031594 neuromuscular junction(GO:0031594)
0.0 1.8 GO:0005901 caveola(GO:0005901)
0.0 1.1 GO:0032420 stereocilium(GO:0032420)
0.0 8.4 GO:0005925 focal adhesion(GO:0005925)
0.0 2.2 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.3 GO:0005795 Golgi stack(GO:0005795)
0.0 4.2 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 2.1 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.3 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 2.4 GO:0000794 condensed nuclear chromosome(GO:0000794)
0.0 0.2 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.4 GO:0000152 nuclear ubiquitin ligase complex(GO:0000152)
0.0 1.1 GO:0005819 spindle(GO:0005819)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.6 10.2 GO:0050436 microfibril binding(GO:0050436)
2.2 6.5 GO:0050253 sterol esterase activity(GO:0004771) retinyl-palmitate esterase activity(GO:0050253)
2.1 12.6 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
1.5 14.8 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
1.2 11.9 GO:0031014 troponin T binding(GO:0031014)
1.1 79.1 GO:0008307 structural constituent of muscle(GO:0008307)
0.8 3.3 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.8 3.1 GO:0048030 disaccharide binding(GO:0048030)
0.8 3.1 GO:0031708 endothelin B receptor binding(GO:0031708)
0.7 3.0 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.7 2.2 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.7 3.6 GO:0019767 IgE receptor activity(GO:0019767)
0.7 4.1 GO:0030280 structural constituent of epidermis(GO:0030280)
0.7 4.1 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.7 2.7 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.7 2.0 GO:0004958 prostaglandin F receptor activity(GO:0004958)
0.7 3.3 GO:0070051 fibrinogen binding(GO:0070051)
0.6 6.5 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.6 1.8 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.5 2.2 GO:0004995 tachykinin receptor activity(GO:0004995)
0.5 8.3 GO:0045294 alpha-catenin binding(GO:0045294)
0.5 1.5 GO:0070773 protein-N-terminal glutamine amidohydrolase activity(GO:0070773)
0.5 3.6 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.5 2.5 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.5 2.0 GO:0008160 protein tyrosine phosphatase activator activity(GO:0008160)
0.5 3.4 GO:0047276 N-acetyllactosaminide 3-alpha-galactosyltransferase activity(GO:0047276)
0.5 1.4 GO:0005330 dopamine:sodium symporter activity(GO:0005330)
0.5 0.5 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.4 5.8 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.4 2.7 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.4 1.5 GO:0030172 troponin C binding(GO:0030172)
0.3 2.1 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.3 5.7 GO:0005523 tropomyosin binding(GO:0005523)
0.3 1.0 GO:0038100 nodal binding(GO:0038100)
0.3 3.0 GO:0004126 cytidine deaminase activity(GO:0004126)
0.3 1.6 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.3 2.2 GO:0004111 creatine kinase activity(GO:0004111)
0.3 9.5 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.3 4.4 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.3 38.5 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.3 5.4 GO:0038191 neuropilin binding(GO:0038191)
0.3 2.6 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.3 3.4 GO:0070700 BMP receptor binding(GO:0070700)
0.3 2.4 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.3 1.5 GO:0035877 death effector domain binding(GO:0035877)
0.3 1.5 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.2 0.7 GO:0000402 open form four-way junction DNA binding(GO:0000401) crossed form four-way junction DNA binding(GO:0000402)
0.2 2.4 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.2 2.1 GO:0038132 neuregulin binding(GO:0038132)
0.2 1.4 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.2 0.7 GO:0005171 hepatocyte growth factor receptor binding(GO:0005171)
0.2 3.0 GO:0001069 regulatory region RNA binding(GO:0001069)
0.2 1.3 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.2 1.5 GO:0015315 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.2 1.4 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.2 5.5 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.2 3.7 GO:0035497 cAMP response element binding(GO:0035497)
0.2 2.0 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.2 0.5 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.2 1.2 GO:0016018 cyclosporin A binding(GO:0016018)
0.2 2.4 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.2 1.4 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.2 4.4 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.2 0.8 GO:0005275 amine transmembrane transporter activity(GO:0005275)
0.2 0.6 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.2 1.6 GO:0001594 trace-amine receptor activity(GO:0001594)
0.2 1.4 GO:0042285 xylosyltransferase activity(GO:0042285)
0.2 1.7 GO:0033691 sialic acid binding(GO:0033691)
0.2 3.7 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.2 1.8 GO:0031852 mu-type opioid receptor binding(GO:0031852)
0.2 1.1 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.1 1.6 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.1 1.9 GO:0071253 connexin binding(GO:0071253)
0.1 1.3 GO:0000150 recombinase activity(GO:0000150)
0.1 5.4 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.1 2.4 GO:0043495 protein anchor(GO:0043495)
0.1 4.8 GO:0043236 laminin binding(GO:0043236)
0.1 2.7 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 0.5 GO:0016842 amidine-lyase activity(GO:0016842)
0.1 2.0 GO:0030274 LIM domain binding(GO:0030274)
0.1 1.7 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.1 1.3 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.1 1.4 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.1 1.2 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.1 1.5 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.1 2.1 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.1 1.4 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.1 2.8 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.1 0.9 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.1 4.0 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.1 2.4 GO:0031005 filamin binding(GO:0031005)
0.1 4.9 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 4.7 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.1 2.7 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.1 4.7 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 27.8 GO:0008236 serine-type peptidase activity(GO:0008236)
0.1 1.7 GO:0005522 profilin binding(GO:0005522)
0.1 7.1 GO:0070888 E-box binding(GO:0070888)
0.1 1.6 GO:0015245 fatty acid transporter activity(GO:0015245)
0.1 0.5 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.1 3.3 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.1 1.6 GO:0045499 chemorepellent activity(GO:0045499)
0.1 1.8 GO:0030548 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.1 2.7 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 0.4 GO:1902379 chemoattractant activity involved in axon guidance(GO:1902379)
0.1 1.1 GO:0070097 delta-catenin binding(GO:0070097)
0.1 3.9 GO:0071837 HMG box domain binding(GO:0071837)
0.1 2.7 GO:0050840 extracellular matrix binding(GO:0050840)
0.1 0.9 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.1 0.9 GO:0016004 phospholipase activator activity(GO:0016004)
0.1 2.6 GO:0008143 poly(A) binding(GO:0008143)
0.1 0.7 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.1 0.5 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.1 1.7 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.1 3.7 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.1 1.0 GO:1990226 histone methyltransferase binding(GO:1990226)
0.1 0.4 GO:0050816 phosphothreonine binding(GO:0050816)
0.1 0.7 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.1 1.9 GO:0030506 ankyrin binding(GO:0030506)
0.1 2.8 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.1 0.6 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.1 1.3 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.1 1.8 GO:0048156 tau protein binding(GO:0048156)
0.1 0.3 GO:0031800 type 3 metabotropic glutamate receptor binding(GO:0031800)
0.1 3.9 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1 1.1 GO:0051011 microtubule minus-end binding(GO:0051011)
0.1 2.0 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.1 1.3 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.1 3.5 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.1 2.6 GO:0071889 14-3-3 protein binding(GO:0071889)
0.1 1.0 GO:0015250 water channel activity(GO:0015250)
0.1 1.6 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 3.2 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1 0.2 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.1 2.6 GO:0042169 SH2 domain binding(GO:0042169)
0.1 0.5 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.1 2.4 GO:0003785 actin monomer binding(GO:0003785)
0.1 31.5 GO:0003779 actin binding(GO:0003779)
0.1 2.8 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 2.0 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.7 GO:0015197 peptide transporter activity(GO:0015197)
0.0 1.3 GO:0015026 coreceptor activity(GO:0015026)
0.0 0.6 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 3.6 GO:0097110 scaffold protein binding(GO:0097110)
0.0 1.5 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.6 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 6.4 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 1.3 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 2.3 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 0.7 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.7 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.5 GO:0001158 enhancer sequence-specific DNA binding(GO:0001158)
0.0 0.4 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.0 1.9 GO:0050699 WW domain binding(GO:0050699)
0.0 0.3 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.3 GO:0043560 insulin receptor substrate binding(GO:0043560)
0.0 0.9 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 1.3 GO:0008378 galactosyltransferase activity(GO:0008378)
0.0 0.6 GO:0003993 acid phosphatase activity(GO:0003993)
0.0 1.2 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 1.0 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.4 GO:0019215 intermediate filament binding(GO:0019215)
0.0 1.8 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.4 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 4.1 GO:0008565 protein transporter activity(GO:0008565)
0.0 0.4 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0 11.3 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.6 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 1.1 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.1 GO:0004052 arachidonate 12-lipoxygenase activity(GO:0004052)
0.0 0.2 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.0 0.3 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.0 0.5 GO:0070034 telomerase RNA binding(GO:0070034)
0.0 0.2 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 14.6 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.1 GO:0098821 BMP receptor activity(GO:0098821)
0.0 0.6 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 4.2 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 1.4 GO:0003823 antigen binding(GO:0003823)
0.0 0.3 GO:0016783 sulfurtransferase activity(GO:0016783)
0.0 0.3 GO:0004180 carboxypeptidase activity(GO:0004180)
0.0 0.5 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.4 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.3 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.8 GO:0005109 frizzled binding(GO:0005109)
0.0 0.2 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.1 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.1 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.0 0.7 GO:0005518 collagen binding(GO:0005518)
0.0 0.2 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.0 0.1 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 1.3 GO:0015108 chloride transmembrane transporter activity(GO:0015108)
0.0 1.3 GO:0001076 transcription factor activity, RNA polymerase II transcription factor binding(GO:0001076)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 7.2 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.7 3.4 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.4 14.1 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.4 6.5 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.3 11.2 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.2 6.4 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.2 1.7 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.2 5.3 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.2 1.4 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.2 4.0 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.2 6.2 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.2 10.1 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.1 2.4 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 3.3 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.1 7.6 PID AURORA B PATHWAY Aurora B signaling
0.1 3.5 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.1 4.5 PID MYC PATHWAY C-MYC pathway
0.1 2.2 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.1 11.0 PID IL4 2PATHWAY IL4-mediated signaling events
0.1 7.3 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.1 9.7 PID ILK PATHWAY Integrin-linked kinase signaling
0.1 3.7 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.1 5.3 PID NCADHERIN PATHWAY N-cadherin signaling events
0.1 2.6 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.1 5.5 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.1 1.4 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1 1.4 PID GLYPICAN 1PATHWAY Glypican 1 network
0.1 2.8 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.1 4.9 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 1.7 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.1 3.3 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.1 2.2 PID IL1 PATHWAY IL1-mediated signaling events
0.1 3.6 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.1 3.1 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.1 3.6 PID RAS PATHWAY Regulation of Ras family activation
0.1 4.1 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1 4.2 PID ENDOTHELIN PATHWAY Endothelins
0.1 0.8 PID TRAIL PATHWAY TRAIL signaling pathway
0.1 12.5 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.1 2.1 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.1 0.9 PID EPO PATHWAY EPO signaling pathway
0.1 1.6 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.1 3.2 PID PLK1 PATHWAY PLK1 signaling events
0.1 0.9 ST P38 MAPK PATHWAY p38 MAPK Pathway
0.1 0.4 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.1 2.3 PID ERBB4 PATHWAY ErbB4 signaling events
0.1 2.2 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.9 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.0 1.5 PID BMP PATHWAY BMP receptor signaling
0.0 1.7 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 2.1 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 0.8 PID BARD1 PATHWAY BARD1 signaling events
0.0 1.4 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 2.2 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 3.2 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 2.7 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.5 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 1.1 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 1.4 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 0.5 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.6 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 0.6 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 0.4 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 0.4 PID BCR 5PATHWAY BCR signaling pathway
0.0 2.6 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 5.4 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.2 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 1.7 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 0.9 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 0.9 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.6 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.7 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.3 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.5 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 74.0 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.7 2.0 REACTOME FGFR1 LIGAND BINDING AND ACTIVATION Genes involved in FGFR1 ligand binding and activation
0.4 10.8 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.4 11.5 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.4 7.2 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.3 7.3 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.3 15.6 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.3 9.1 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.3 3.6 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.2 3.6 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.2 2.0 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.2 5.4 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.2 3.4 REACTOME POL SWITCHING Genes involved in Polymerase switching
0.2 0.6 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.2 5.3 REACTOME TRAF6 MEDIATED NFKB ACTIVATION Genes involved in TRAF6 mediated NF-kB activation
0.2 5.9 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.2 5.7 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.2 1.4 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 0.8 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.1 4.2 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.1 1.8 REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.1 3.6 REACTOME ACTIVATED POINT MUTANTS OF FGFR2 Genes involved in Activated point mutants of FGFR2
0.1 1.6 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.1 3.0 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.1 6.7 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.1 2.0 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 9.4 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.1 3.6 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1 4.1 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.1 3.9 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.1 2.2 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.1 3.2 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.1 0.6 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.1 2.4 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.1 1.0 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.1 3.3 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.1 0.9 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.1 0.8 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.1 3.0 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.1 1.7 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.1 1.8 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 2.4 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 1.4 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 1.1 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 2.3 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 2.2 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 2.2 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.9 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 0.5 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.0 0.5 REACTOME GLUCAGON TYPE LIGAND RECEPTORS Genes involved in Glucagon-type ligand receptors
0.0 0.9 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 5.4 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.3 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.5 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0 0.3 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 0.1 REACTOME DEFENSINS Genes involved in Defensins
0.0 1.9 REACTOME TOLL RECEPTOR CASCADES Genes involved in Toll Receptor Cascades
0.0 0.4 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 5.2 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 1.2 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.3 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 1.1 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 1.3 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.3 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 1.0 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.3 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.2 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)