Project

PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

Navigation
Downloads

Results for Tcf7l1

Z-value: 0.83

Motif logo

Transcription factors associated with Tcf7l1

Gene Symbol Gene ID Gene Info
ENSMUSG00000055799.14 Tcf7l1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Tcf7l1mm39_v1_chr6_-_72765935_727660440.343.7e-03Click!

Activity profile of Tcf7l1 motif

Sorted Z-values of Tcf7l1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Tcf7l1

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image
Promoter Score Transcript Gene Gene Info
chr12_-_76842263 6.84 ENSMUST00000082431.6
glutathione peroxidase 2
chr5_-_134975773 5.13 ENSMUST00000051401.4
claudin 4
chr15_+_102898966 4.55 ENSMUST00000001703.8
homeobox C8
chrX_+_72527208 4.54 ENSMUST00000033741.15
ENSMUST00000169489.2
biglycan
chr11_+_96820220 4.39 ENSMUST00000062172.6
proline rich 15-like
chr6_-_83504471 4.39 ENSMUST00000141904.8
actin, gamma 2, smooth muscle, enteric
chr11_+_96820091 4.01 ENSMUST00000054311.6
ENSMUST00000107636.4
proline rich 15-like
chr18_+_21205386 3.99 ENSMUST00000082235.5
meprin 1 beta
chr10_+_79986280 3.75 ENSMUST00000153477.8
midnolin
chr17_-_71158184 3.37 ENSMUST00000059775.15
TGFB-induced factor homeobox 1
chr2_-_69416365 3.26 ENSMUST00000100051.9
ENSMUST00000092551.5
ENSMUST00000080953.12
low density lipoprotein receptor-related protein 2
chr3_-_144638284 3.25 ENSMUST00000098549.4
chloride channel accessory 4B
chr6_+_21985902 3.23 ENSMUST00000115383.9
cadherin-like and PC-esterase domain containing 1
chr17_-_71158052 3.22 ENSMUST00000186358.6
TGFB-induced factor homeobox 1
chr12_+_113104085 3.20 ENSMUST00000200380.5
cysteine rich protein 2
chr3_-_92594516 3.16 ENSMUST00000029524.4
late cornified envelope 1D
chr4_+_141148068 3.12 ENSMUST00000102486.5
heat shock protein family, member 7 (cardiovascular)
chr2_-_65068960 3.11 ENSMUST00000112429.9
ENSMUST00000102726.8
ENSMUST00000112430.8
Cobl-like 1
chr2_-_65068917 3.11 ENSMUST00000090896.10
ENSMUST00000155082.2
Cobl-like 1
chr9_+_98372575 3.10 ENSMUST00000035029.3
retinol binding protein 2, cellular
chr8_+_21691577 3.05 ENSMUST00000110754.2
defensin, alpha, 41
chr4_+_11758147 3.02 ENSMUST00000029871.12
ENSMUST00000108303.2
cadherin 17
chr12_+_113103817 3.02 ENSMUST00000084882.9
cysteine rich protein 2
chr6_-_52211882 2.97 ENSMUST00000125581.2
homeobox A10
chr14_+_101967343 2.93 ENSMUST00000100337.10
LIM domain only 7
chr6_+_17065141 2.89 ENSMUST00000115467.11
ENSMUST00000154266.3
ENSMUST00000076654.9
testin LIM domain protein
chr4_-_94538329 2.86 ENSMUST00000107101.2
leucine rich repeat containing 19
chr2_+_70305267 2.80 ENSMUST00000100043.3
trans-acting transcription factor 5
chrX_+_162923474 2.71 ENSMUST00000073973.11
angiotensin I converting enzyme (peptidyl-dipeptidase A) 2
chr10_+_38841511 2.70 ENSMUST00000019992.6
laminin, alpha 4
chr11_-_52174129 2.66 ENSMUST00000109071.3
transcription factor 7, T cell specific
chr17_+_75312520 2.64 ENSMUST00000234490.2
ENSMUST00000001927.12
latent transforming growth factor beta binding protein 1
chr17_-_68311073 2.61 ENSMUST00000024840.12
Rho GTPase activating protein 28
chr10_-_85847697 2.59 ENSMUST00000105304.2
ENSMUST00000061699.12
BPI fold containing family C
chr6_+_21986445 2.59 ENSMUST00000115382.8
cadherin-like and PC-esterase domain containing 1
chr11_+_108812474 2.45 ENSMUST00000144511.2
axin 2
chr3_+_122688721 2.43 ENSMUST00000023820.6
fatty acid binding protein 2, intestinal
chr3_-_92555608 2.42 ENSMUST00000074142.7
late cornified envelope 1A1
chr3_-_75864195 2.42 ENSMUST00000038563.14
ENSMUST00000167078.8
ENSMUST00000117242.8
golgi integral membrane protein 4
chr1_-_181847492 2.36 ENSMUST00000177811.8
ENSMUST00000111025.8
ENSMUST00000111024.10
ENAH actin regulator
chr6_-_148846247 2.34 ENSMUST00000111562.8
ENSMUST00000081956.12
SIN3-HDAC complex associated factor
chr18_+_4921663 2.32 ENSMUST00000143254.8
supervillin
chr12_-_84455764 2.31 ENSMUST00000120942.8
ENSMUST00000110272.9
ectonucleoside triphosphate diphosphohydrolase 5
chr12_-_112766266 2.30 ENSMUST00000239525.1
AHNAK nucleoprotein 2
chr12_-_16850674 2.25 ENSMUST00000162112.8
gene regulated by estrogen in breast cancer protein
chr3_-_92616380 2.24 ENSMUST00000090867.2
late cornified envelope 1E
chr14_+_34097474 2.24 ENSMUST00000227130.2
multimerin 2
chr11_+_108811626 2.19 ENSMUST00000140821.2
axin 2
chr4_-_94538370 2.19 ENSMUST00000053419.9
leucine rich repeat containing 19
chr2_+_74535242 2.14 ENSMUST00000019749.4
homeobox D8
chr7_+_43460718 2.11 ENSMUST00000032955.7
kallikrein related-peptidase 7 (chymotryptic, stratum corneum)
chr2_-_35322581 2.09 ENSMUST00000079424.11
glycoprotein galactosyltransferase alpha 1, 3
chr9_+_90045219 2.09 ENSMUST00000147250.8
ENSMUST00000113060.3
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 7
chr9_+_90045109 2.08 ENSMUST00000113059.8
ENSMUST00000167122.8
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 7
chr14_+_34097422 2.07 ENSMUST00000111908.3
multimerin 2
chr6_+_29735666 2.06 ENSMUST00000001812.5
smoothened, frizzled class receptor
chr8_+_79755194 2.04 ENSMUST00000119254.8
ENSMUST00000238669.2
zinc finger protein 827
chr2_+_174602412 1.99 ENSMUST00000029030.9
endothelin 3
chr13_-_119545479 1.99 ENSMUST00000223268.2
nicotinamide nucleotide transhydrogenase
chr11_-_48836975 1.99 ENSMUST00000104958.2
protease (prosome, macropain) activator subunit 2B
chr8_+_93084253 1.98 ENSMUST00000210246.2
ENSMUST00000034184.12
Iroquois homeobox 5
chr15_-_54141816 1.95 ENSMUST00000079772.4
tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin)
chr14_+_102078038 1.93 ENSMUST00000159314.8
LIM domain only 7
chr11_-_53959790 1.89 ENSMUST00000018755.10
PDZ and LIM domain 4
chr11_-_53959758 1.89 ENSMUST00000093109.11
PDZ and LIM domain 4
chr13_-_119545520 1.86 ENSMUST00000069902.13
ENSMUST00000099149.10
ENSMUST00000109204.8
nicotinamide nucleotide transhydrogenase
chr7_-_144493560 1.86 ENSMUST00000093962.5
cyclin D1
chr8_+_79754980 1.83 ENSMUST00000087927.11
ENSMUST00000098614.9
zinc finger protein 827
chr1_-_86039692 1.82 ENSMUST00000027431.7
5-hydroxytryptamine (serotonin) receptor 2B
chr6_+_83034825 1.81 ENSMUST00000077502.5
DEAQ RNA-dependent ATPase
chr6_-_47571901 1.80 ENSMUST00000081721.13
ENSMUST00000114618.8
ENSMUST00000114616.8
enhancer of zeste 2 polycomb repressive complex 2 subunit
chr6_-_47790272 1.78 ENSMUST00000077290.9
protein disulfide isomerase associated 4
chr7_+_88079534 1.78 ENSMUST00000208478.2
RAB38, member RAS oncogene family
chr19_-_47907705 1.77 ENSMUST00000095998.7
inositol 1,4,5-triphosphate receptor interacting protein
chr11_-_86999481 1.77 ENSMUST00000051395.9
proline rich 11
chr10_-_4337435 1.73 ENSMUST00000100077.5
zinc finger and BTB domain containing 2
chr1_-_37996838 1.69 ENSMUST00000027254.10
ENSMUST00000114894.2
lysozyme G-like 1
chr2_+_74534959 1.69 ENSMUST00000151380.2
homeobox D8
chr10_+_96453408 1.69 ENSMUST00000218953.2
BTG anti-proliferation factor 1
chr17_+_37504783 1.68 ENSMUST00000038844.7
ubiquitin D
chr17_+_29712008 1.67 ENSMUST00000234665.2
proviral integration site 1
chr10_+_79986988 1.66 ENSMUST00000146516.8
ENSMUST00000144526.2
midnolin
chr10_+_126836578 1.64 ENSMUST00000026500.12
ENSMUST00000142698.8
advillin
chr3_+_92874366 1.60 ENSMUST00000098886.5
late cornified envelope 3E
chr10_-_4338032 1.59 ENSMUST00000100078.10
zinc finger and BTB domain containing 2
chr14_+_26760898 1.59 ENSMUST00000035336.5
interleukin 17 receptor D
chr4_-_34882917 1.58 ENSMUST00000098163.9
ENSMUST00000047950.6
zinc finger protein 292
chr14_-_70761507 1.56 ENSMUST00000022692.5
surfactant associated protein C
chr15_-_58078274 1.56 ENSMUST00000022986.8
F-box protein 32
chrX_-_133062677 1.51 ENSMUST00000033611.5
X-linked Kx blood group related, X-linked
chr2_+_121188195 1.51 ENSMUST00000125812.8
ENSMUST00000078222.9
ENSMUST00000125221.3
ENSMUST00000150271.8
creatine kinase, mitochondrial 1, ubiquitous
chr13_-_103042554 1.49 ENSMUST00000171791.8
microtubule associated serine/threonine kinase family member 4
chr13_-_103042294 1.49 ENSMUST00000167462.8
microtubule associated serine/threonine kinase family member 4
chr5_-_147244074 1.47 ENSMUST00000031650.4
caudal type homeobox 2
chr11_+_120382666 1.46 ENSMUST00000026899.4
solute carrier family 25 (mitochondrial carrier, dicarboxylate transporter), member 10
chr14_-_98406977 1.46 ENSMUST00000071533.13
ENSMUST00000069334.8
dachshund family transcription factor 1
chr6_+_86605146 1.41 ENSMUST00000043400.9
aspartic peptidase, retroviral-like 1
chr3_+_88439616 1.40 ENSMUST00000172699.2
mex3 RNA binding family member A
chr10_-_13264497 1.40 ENSMUST00000105546.8
phosphatase and actin regulator 2
chr8_+_21805562 1.40 ENSMUST00000167683.3
ENSMUST00000168340.2
defensin, alpha, 27
chr10_-_61814852 1.39 ENSMUST00000105453.8
ENSMUST00000105452.9
ENSMUST00000105454.3
collagen, type XIII, alpha 1
chr1_+_107289659 1.38 ENSMUST00000027566.3
serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 11
chr14_+_26761023 1.37 ENSMUST00000223942.2
interleukin 17 receptor D
chr11_+_95010935 1.37 ENSMUST00000092768.7
distal-less homeobox 3
chr11_-_86964881 1.36 ENSMUST00000020804.8
glycerophosphodiester phosphodiesterase domain containing 1
chr9_-_57552392 1.34 ENSMUST00000216934.2
c-src tyrosine kinase
chr1_-_182929025 1.34 ENSMUST00000171366.7
dispatched RND transporter family member 1
chr8_+_22996233 1.33 ENSMUST00000210854.2
solute carrier family 20, member 2
chr12_-_114487525 1.33 ENSMUST00000103495.3
immunoglobulin heavy variable V10-3
chr7_+_24310738 1.32 ENSMUST00000073325.6
pleckstrin homology like domain, family B, member 3
chr18_-_61169262 1.32 ENSMUST00000025521.9
caudal type homeobox 1
chr11_-_49603501 1.31 ENSMUST00000020624.7
ENSMUST00000145353.8
CCR4-NOT transcription complex, subunit 6
chr12_-_21467437 1.31 ENSMUST00000103002.8
ENSMUST00000155480.9
ENSMUST00000135088.9
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta
chr8_+_61677253 1.30 ENSMUST00000209611.2
SH3 domain containing ring finger 1
chr2_+_174602574 1.30 ENSMUST00000140908.2
endothelin 3
chr4_+_62501737 1.28 ENSMUST00000098031.10
regulator of G-protein signaling 3
chr12_+_76118790 1.28 ENSMUST00000131480.8
spectrin repeat containing, nuclear envelope 2
chr12_-_98703664 1.28 ENSMUST00000170188.8
protein tyrosine phosphatase, non-receptor type 21
chr9_+_45014092 1.26 ENSMUST00000217074.2
junction adhesion molecule like
chr7_+_78922947 1.26 ENSMUST00000037315.13
abhydrolase domain containing 2
chr2_+_172863688 1.24 ENSMUST00000029014.16
RNA binding motif protein 38
chr1_+_39940189 1.23 ENSMUST00000191761.6
ENSMUST00000193682.6
ENSMUST00000195860.6
ENSMUST00000195259.6
ENSMUST00000195636.6
ENSMUST00000192509.6
mitogen-activated protein kinase kinase kinase kinase 4
chr3_+_32763313 1.23 ENSMUST00000126144.3
actin-like 6A
chr2_-_143704853 1.23 ENSMUST00000099296.4
beaded filament structural protein 1, in lens-CP94
chr17_+_48037758 1.21 ENSMUST00000024782.12
ENSMUST00000144955.2
progastricsin (pepsinogen C)
chr3_-_122413361 1.21 ENSMUST00000239148.2
ENSMUST00000162409.8
ENSMUST00000162947.3
formin binding protein 1-like
chr11_+_108811168 1.17 ENSMUST00000052915.14
axin 2
chr11_+_108814007 1.16 ENSMUST00000106711.2
axin 2
chr6_+_87350292 1.14 ENSMUST00000032128.6
gastrokine 2
chr17_-_79328157 1.14 ENSMUST00000168887.8
ENSMUST00000119284.8
protein kinase D3
chr1_-_64161415 1.13 ENSMUST00000135075.2
Kruppel-like factor 7 (ubiquitous)
chr13_+_94219934 1.11 ENSMUST00000156071.2
lipoma HMGIC fusion partner-like 2
chr7_+_5018453 1.10 ENSMUST00000086349.5
ENSMUST00000207050.2
zinc finger protein 524
predicted gene 44973
chr17_+_36176485 1.09 ENSMUST00000127442.8
ENSMUST00000144382.8
protein phosphatase 1, regulatory subunit 18
chr2_+_13579092 1.09 ENSMUST00000193675.2
vimentin
chr4_+_57782150 1.08 ENSMUST00000124581.2
paralemmin A kinase anchor protein
chr14_+_102077937 1.07 ENSMUST00000159026.8
LIM domain only 7
chr14_-_55204023 1.06 ENSMUST00000124930.8
myosin, heavy polypeptide 6, cardiac muscle, alpha
chrX_+_158771429 1.05 ENSMUST00000033665.9
mitogen-activated protein kinase kinase kinase 15
chr1_+_136395673 1.05 ENSMUST00000189413.7
ENSMUST00000047817.12
kinesin family member 14
chr9_+_35334878 1.04 ENSMUST00000154652.8
cell adhesion molecule-related/down-regulated by oncogenes
chr14_+_21549798 1.03 ENSMUST00000182855.8
ENSMUST00000182405.9
ENSMUST00000069648.14
K(lysine) acetyltransferase 6B
chr13_-_103233323 1.01 ENSMUST00000166336.9
ENSMUST00000239261.2
ENSMUST00000194446.7
microtubule associated serine/threonine kinase family member 4
chr19_+_25214322 1.01 ENSMUST00000049400.15
KN motif and ankyrin repeat domains 1
chr19_+_56276343 1.00 ENSMUST00000095948.11
hyaluronic acid binding protein 2
chr7_+_44866095 1.00 ENSMUST00000209437.2
TEA domain family member 2
chr3_+_32762656 1.00 ENSMUST00000029214.14
actin-like 6A
chr11_-_61610772 0.98 ENSMUST00000151780.8
ENSMUST00000148584.2
solute carrier family 5 (sodium/glucose cotransporter), member 10
chr18_-_88912446 0.98 ENSMUST00000070116.12
ENSMUST00000125362.8
suppressor of cytokine signaling 6
chr17_+_36176948 0.95 ENSMUST00000122899.8
protein phosphatase 1, regulatory subunit 18
chr2_+_156928962 0.95 ENSMUST00000166140.8
TBC/LysM associated domain containing 2
chr10_-_13264574 0.94 ENSMUST00000079698.7
phosphatase and actin regulator 2
chr9_-_57552844 0.94 ENSMUST00000216979.2
ENSMUST00000034863.8
c-src tyrosine kinase
chr6_-_52195663 0.93 ENSMUST00000134367.4
homeobox A7
chr4_-_58553553 0.92 ENSMUST00000107575.9
ENSMUST00000107574.8
ENSMUST00000147354.8
lysophosphatidic acid receptor 1
chr16_+_87495792 0.92 ENSMUST00000026703.6
BTB and CNC homology 1, basic leucine zipper transcription factor 1
chr13_+_22129246 0.89 ENSMUST00000176511.8
ENSMUST00000102978.8
ENSMUST00000152258.9
zinc finger protein 184 (Kruppel-like)
chr13_-_99062882 0.88 ENSMUST00000109401.8
transportin 1
chr7_+_98484311 0.88 ENSMUST00000165122.8
ENSMUST00000067495.9
wingless-type MMTV integration site family, member 11
chr9_-_65734826 0.87 ENSMUST00000159109.2
zinc finger protein 609
chr3_-_116762476 0.87 ENSMUST00000119557.8
palmdelphin
chr14_-_70414236 0.87 ENSMUST00000153735.8
PDZ and LIM domain 2
chr2_-_59955995 0.86 ENSMUST00000112550.8
bromodomain adjacent to zinc finger domain, 2B
chr4_-_126362372 0.85 ENSMUST00000097888.10
ENSMUST00000239399.2
argonaute RISC catalytic subunit 1
chr8_+_22073022 0.85 ENSMUST00000098887.4
defensin, alpha, 28
chr7_-_110681402 0.85 ENSMUST00000159305.2
eukaryotic translation initiation factor 4, gamma 2
chr17_+_35295849 0.81 ENSMUST00000172494.8
lymphocyte antigen 6 complex, locus G6E
chr7_+_65759198 0.81 ENSMUST00000036372.8
chondroitin sulfate synthase 1
chrX_-_149595711 0.81 ENSMUST00000112697.10
MAGE family member D2
chr2_+_18677195 0.79 ENSMUST00000171845.8
ENSMUST00000061158.5
COMM domain containing 3
chr7_-_49286594 0.78 ENSMUST00000032717.7
developing brain homeobox 1
chr2_+_160573604 0.78 ENSMUST00000174885.2
ENSMUST00000109462.8
phospholipase C, gamma 1
chr11_+_69737200 0.76 ENSMUST00000108632.8
phospholipid scramblase 3
chr18_+_82932747 0.76 ENSMUST00000071233.7
zinc finger protein 516
chr12_-_31401432 0.75 ENSMUST00000110857.5
dihydrolipoamide dehydrogenase
chr19_-_4384029 0.74 ENSMUST00000176653.2
lysine (K)-specific demethylase 2A
chr8_-_41507808 0.72 ENSMUST00000093534.11
mitochondrial tumor suppressor 1
chr2_+_172864153 0.72 ENSMUST00000173997.2
RNA binding motif protein 38
chr19_-_41790458 0.72 ENSMUST00000026150.15
ENSMUST00000163265.9
ENSMUST00000177495.2
Rho GTPase activating protein 19
chr7_+_67305162 0.72 ENSMUST00000107470.2
tetratricopeptide repeat domain 23
chr18_+_61688329 0.71 ENSMUST00000165123.8
casein kinase 1, alpha 1
chr18_-_88912322 0.71 ENSMUST00000123826.2
suppressor of cytokine signaling 6
chr1_-_4479445 0.71 ENSMUST00000208660.2
retinitis pigmentosa 1 (human)
chr1_-_58735106 0.70 ENSMUST00000055313.14
ENSMUST00000188772.7
flagellum associated containing coiled-coil domains 1
chr15_-_37008011 0.70 ENSMUST00000226671.2
zinc finger protein 706
chr11_+_114742619 0.69 ENSMUST00000053361.12
ENSMUST00000021071.14
ENSMUST00000136785.2
G protein-coupled receptor, family C, group 5, member C
chr12_-_51876282 0.69 ENSMUST00000042052.9
ENSMUST00000179265.8
HECT domain E3 ubiquitin protein ligase 1
chr12_+_76128405 0.68 ENSMUST00000154509.8
spectrin repeat containing, nuclear envelope 2
chr7_+_126359869 0.68 ENSMUST00000206272.2
mitogen-activated protein kinase 3
chr2_+_152873772 0.66 ENSMUST00000037235.7
X-linked Kx blood group related 7
chr1_-_180524587 0.65 ENSMUST00000027778.8
Mix1 homeobox-like 1 (Xenopus laevis)
chr17_-_46513499 0.63 ENSMUST00000024749.9
polymerase (DNA directed), eta (RAD 30 related)
chrX_-_149595873 0.62 ENSMUST00000131241.2
ENSMUST00000147152.3
ENSMUST00000143843.8
MAGE family member D2
chr5_+_31350566 0.62 ENSMUST00000031029.15
ENSMUST00000201679.4
sorting nexin 17
chr17_-_34822649 0.62 ENSMUST00000015622.8
ring finger protein 5
chr19_+_44481901 0.62 ENSMUST00000041163.5
wingless-type MMTV integration site family, member 8B
chr5_+_36050663 0.61 ENSMUST00000064571.11
actin filament associated protein 1
chr5_+_31350607 0.61 ENSMUST00000201535.4
sorting nexin 17
chr1_-_37580084 0.61 ENSMUST00000151952.8
mannoside acetylglucosaminyltransferase 4, isoenzyme A
chr11_-_99501015 0.60 ENSMUST00000076478.2
predicted gene 11937

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 6.8 GO:0009609 response to symbiont(GO:0009608) response to symbiotic bacterium(GO:0009609)
1.3 3.9 GO:0006740 NADPH regeneration(GO:0006740)
1.2 7.0 GO:0032423 regulation of mismatch repair(GO:0032423) regulation of chondrocyte development(GO:0061181) negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
1.0 3.0 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.7 5.4 GO:0033132 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.7 2.7 GO:0015801 aromatic amino acid transport(GO:0015801) tryptophan transport(GO:0015827)
0.7 3.3 GO:0002225 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antibacterial peptide production(GO:0002803)
0.7 2.6 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.6 1.8 GO:0071707 immunoglobulin heavy chain V-D-J recombination(GO:0071707)
0.6 1.8 GO:1903334 positive regulation of protein folding(GO:1903334)
0.5 3.3 GO:0003100 regulation of systemic arterial blood pressure by endothelin(GO:0003100) vein smooth muscle contraction(GO:0014826)
0.5 2.1 GO:0042125 protein glycosylation at cell surface(GO:0033575) protein galactosylation at cell surface(GO:0033580) protein galactosylation(GO:0042125)
0.5 1.6 GO:0014878 response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
0.5 2.1 GO:0007228 positive regulation of hh target transcription factor activity(GO:0007228)
0.5 1.8 GO:0007208 phospholipase C-activating serotonin receptor signaling pathway(GO:0007208)
0.4 1.3 GO:0035638 patched ligand maturation(GO:0007225) signal maturation(GO:0035638)
0.4 2.0 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.4 1.5 GO:0015744 succinate transport(GO:0015744)
0.3 1.0 GO:0032487 cerebellar cortex structural organization(GO:0021698) regulation of Rap protein signal transduction(GO:0032487) negative regulation of integrin activation(GO:0033624)
0.3 3.1 GO:0006776 vitamin A metabolic process(GO:0006776)
0.3 1.4 GO:0071895 odontoblast differentiation(GO:0071895)
0.3 1.0 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.3 2.7 GO:0033153 somatic diversification of T cell receptor genes(GO:0002568) somatic recombination of T cell receptor gene segments(GO:0002681) T cell receptor V(D)J recombination(GO:0033153)
0.3 1.3 GO:1904566 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.3 2.3 GO:0042997 negative regulation of low-density lipoprotein particle clearance(GO:0010989) negative regulation of Golgi to plasma membrane protein transport(GO:0042997) negative regulation of establishment of protein localization to plasma membrane(GO:0090005)
0.3 6.6 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.3 4.4 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.3 1.9 GO:0000320 re-entry into mitotic cell cycle(GO:0000320)
0.3 1.1 GO:0007522 visceral muscle development(GO:0007522)
0.3 1.3 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.3 1.8 GO:0060155 platelet dense granule organization(GO:0060155) phagosome acidification(GO:0090383) melanosome assembly(GO:1903232)
0.2 1.5 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.2 1.0 GO:0060709 glycogen cell differentiation involved in embryonic placenta development(GO:0060709)
0.2 2.8 GO:0014807 regulation of somitogenesis(GO:0014807)
0.2 6.2 GO:0051639 actin filament network formation(GO:0051639)
0.2 0.9 GO:0060775 positive regulation of transforming growth factor beta2 production(GO:0032915) mediolateral intercalation(GO:0060031) planar cell polarity pathway involved in gastrula mediolateral intercalation(GO:0060775)
0.2 5.1 GO:0061436 establishment of skin barrier(GO:0061436)
0.2 1.7 GO:0000270 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.2 1.7 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.2 0.8 GO:2000657 regulation of apolipoprotein binding(GO:2000656) negative regulation of apolipoprotein binding(GO:2000657)
0.2 2.0 GO:0042483 negative regulation of odontogenesis(GO:0042483)
0.2 0.7 GO:0009106 lipoate metabolic process(GO:0009106)
0.2 0.9 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.2 1.4 GO:0070294 renal sodium ion absorption(GO:0070294)
0.2 1.0 GO:0010966 regulation of phosphate transport(GO:0010966)
0.2 1.7 GO:0031659 positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031659)
0.2 2.0 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.2 1.1 GO:0089700 protein kinase D signaling(GO:0089700)
0.2 11.1 GO:0018149 peptide cross-linking(GO:0018149)
0.1 4.2 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)
0.1 2.7 GO:0070307 lens fiber cell development(GO:0070307)
0.1 1.3 GO:0035696 monocyte extravasation(GO:0035696)
0.1 0.4 GO:0071579 regulation of zinc ion transport(GO:0071579)
0.1 1.7 GO:0070842 aggresome assembly(GO:0070842)
0.1 2.3 GO:0001778 plasma membrane repair(GO:0001778)
0.1 0.5 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.1 2.7 GO:0036342 post-anal tail morphogenesis(GO:0036342)
0.1 0.4 GO:1990697 protein depalmitoleylation(GO:1990697)
0.1 0.7 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.1 2.0 GO:1902400 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977) signal transduction involved in mitotic G1 DNA damage checkpoint(GO:0072431) intracellular signal transduction involved in G1 DNA damage checkpoint(GO:1902400)
0.1 0.7 GO:2000382 positive regulation of mesoderm development(GO:2000382)
0.1 3.3 GO:0045056 transcytosis(GO:0045056)
0.1 1.0 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816)
0.1 2.3 GO:0045821 positive regulation of glycolytic process(GO:0045821)
0.1 3.9 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.1 0.2 GO:1900368 regulation of RNA interference(GO:1900368)
0.1 0.5 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.1 1.3 GO:0021521 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.1 0.6 GO:0006290 pyrimidine dimer repair(GO:0006290)
0.1 0.5 GO:2000210 positive regulation of anoikis(GO:2000210)
0.1 0.5 GO:0070425 negative regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070425) negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070433)
0.1 0.3 GO:0070839 divalent metal ion export(GO:0070839)
0.1 0.8 GO:0035280 miRNA loading onto RISC involved in gene silencing by miRNA(GO:0035280)
0.1 0.7 GO:0033184 positive regulation of histone ubiquitination(GO:0033184)
0.1 1.0 GO:2000291 regulation of myoblast proliferation(GO:2000291)
0.1 0.9 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.1 2.2 GO:0043968 histone H2A acetylation(GO:0043968)
0.1 0.9 GO:1904424 regulation of GTP binding(GO:1904424)
0.1 0.9 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617) negative regulation of monocyte differentiation(GO:0045656)
0.1 1.3 GO:0032570 response to progesterone(GO:0032570)
0.1 0.3 GO:1903760 regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903760)
0.1 1.0 GO:1904659 glucose transmembrane transport(GO:1904659)
0.1 0.4 GO:0097473 cellular response to light intensity(GO:0071484) cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473)
0.1 1.1 GO:0032959 inositol trisphosphate biosynthetic process(GO:0032959)
0.1 0.6 GO:0015691 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.1 4.0 GO:1901998 toxin transport(GO:1901998)
0.1 0.5 GO:0006526 arginine biosynthetic process(GO:0006526)
0.1 1.2 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.1 0.6 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.1 4.5 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.1 0.7 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.1 0.4 GO:1901503 ether lipid biosynthetic process(GO:0008611) neutrophil differentiation(GO:0030223) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.1 2.5 GO:0050892 intestinal absorption(GO:0050892)
0.1 1.3 GO:0006817 phosphate ion transport(GO:0006817)
0.0 3.9 GO:0035904 aorta development(GO:0035904)
0.0 0.3 GO:0002729 positive regulation of natural killer cell cytokine production(GO:0002729)
0.0 1.0 GO:0048339 paraxial mesoderm development(GO:0048339)
0.0 3.5 GO:0050873 brown fat cell differentiation(GO:0050873)
0.0 0.2 GO:0003285 septum secundum development(GO:0003285) atrial septum secundum morphogenesis(GO:0003290)
0.0 0.8 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.0 0.6 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
0.0 0.5 GO:0040016 embryonic cleavage(GO:0040016)
0.0 0.3 GO:0032790 ribosome disassembly(GO:0032790)
0.0 1.4 GO:0034308 primary alcohol metabolic process(GO:0034308)
0.0 1.8 GO:1902042 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902042)
0.0 0.4 GO:0007379 segment specification(GO:0007379)
0.0 0.6 GO:0060481 lobar bronchus epithelium development(GO:0060481)
0.0 0.6 GO:0015809 arginine transport(GO:0015809)
0.0 6.5 GO:0009952 anterior/posterior pattern specification(GO:0009952)
0.0 0.2 GO:0030538 embryonic genitalia morphogenesis(GO:0030538) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334)
0.0 0.2 GO:0072092 ureteric bud invasion(GO:0072092)
0.0 0.9 GO:1903204 negative regulation of oxidative stress-induced neuron death(GO:1903204)
0.0 0.7 GO:0010758 regulation of macrophage chemotaxis(GO:0010758)
0.0 1.4 GO:0001958 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0 1.8 GO:0006334 nucleosome assembly(GO:0006334)
0.0 1.1 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 0.3 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.0 0.4 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 1.6 GO:0051693 actin filament capping(GO:0051693)
0.0 2.7 GO:0009408 response to heat(GO:0009408)
0.0 0.4 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.0 0.2 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.0 0.1 GO:0060789 hair follicle placode formation(GO:0060789)
0.0 0.2 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0 0.5 GO:0007141 male meiosis I(GO:0007141)
0.0 1.5 GO:0042632 cholesterol homeostasis(GO:0042632) sterol homeostasis(GO:0055092)
0.0 0.1 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.0 0.4 GO:0060009 Sertoli cell development(GO:0060009)
0.0 0.5 GO:0007143 female meiotic division(GO:0007143)
0.0 0.5 GO:0022401 desensitization of G-protein coupled receptor protein signaling pathway(GO:0002029) negative adaptation of signaling pathway(GO:0022401)
0.0 0.3 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 1.4 GO:2001237 negative regulation of extrinsic apoptotic signaling pathway(GO:2001237)
0.0 0.3 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.3 GO:0043383 negative T cell selection(GO:0043383)
0.0 0.3 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 0.2 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 0.2 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 1.6 GO:0001843 neural tube closure(GO:0001843) tube closure(GO:0060606)
0.0 0.4 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.0 0.2 GO:1902187 negative regulation of viral release from host cell(GO:1902187)
0.0 0.8 GO:0006446 regulation of translational initiation(GO:0006446)
0.0 0.1 GO:0060313 negative regulation of neutrophil degranulation(GO:0043314) negative regulation of blood vessel remodeling(GO:0060313)
0.0 0.1 GO:0070544 histone H3-K36 demethylation(GO:0070544) negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.0 0.5 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.0 2.3 GO:0007519 skeletal muscle tissue development(GO:0007519)
0.0 0.6 GO:0043029 T cell homeostasis(GO:0043029)
0.0 0.6 GO:0042461 photoreceptor cell development(GO:0042461)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.6 GO:0038045 large latent transforming growth factor-beta complex(GO:0038045)
0.4 2.1 GO:0097209 epidermal lamellar body(GO:0097209)
0.2 1.0 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.2 1.8 GO:0033162 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.2 2.4 GO:0045179 apical cortex(GO:0045179)
0.2 0.7 GO:0043159 acrosomal matrix(GO:0043159)
0.2 9.4 GO:0001533 cornified envelope(GO:0001533)
0.2 2.0 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.2 5.1 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 1.5 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.1 1.6 GO:0097208 alveolar lamellar body(GO:0097208)
0.1 1.9 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 2.1 GO:0044294 dendritic growth cone(GO:0044294)
0.1 3.0 GO:0005605 basal lamina(GO:0005605)
0.1 2.2 GO:0031011 Ino80 complex(GO:0031011)
0.1 1.1 GO:0045098 type III intermediate filament(GO:0045098)
0.1 1.3 GO:0097524 sperm plasma membrane(GO:0097524)
0.1 1.4 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.1 4.8 GO:0016235 aggresome(GO:0016235)
0.1 0.3 GO:0030905 retromer, tubulation complex(GO:0030905)
0.1 4.6 GO:0043034 costamere(GO:0043034)
0.1 3.3 GO:0005719 nuclear euchromatin(GO:0005719)
0.1 1.8 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 0.8 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1 0.7 GO:0097542 ciliary tip(GO:0097542)
0.1 0.8 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.4 GO:0042587 glycogen granule(GO:0042587)
0.0 0.8 GO:0031143 pseudopodium(GO:0031143)
0.0 0.6 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.0 2.0 GO:0001772 immunological synapse(GO:0001772)
0.0 0.3 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 1.0 GO:0000786 nucleosome(GO:0000786)
0.0 4.6 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 4.1 GO:0005604 basement membrane(GO:0005604)
0.0 1.7 GO:0008180 COP9 signalosome(GO:0008180)
0.0 4.5 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.2 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369) catenin-TCF7L2 complex(GO:0071664)
0.0 3.3 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 0.5 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.1 GO:1990032 parallel fiber(GO:1990032)
0.0 2.1 GO:0031985 Golgi cisterna(GO:0031985)
0.0 9.2 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 0.4 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.4 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 3.3 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 1.0 GO:0051233 spindle midzone(GO:0051233)
0.0 0.4 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 1.1 GO:0045178 basal part of cell(GO:0045178)
0.0 6.6 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 2.6 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.2 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 2.6 GO:0072562 blood microparticle(GO:0072562)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.3 GO:0042954 lipoprotein transporter activity(GO:0042954)
0.8 3.3 GO:0031708 endothelin B receptor binding(GO:0031708)
0.8 3.2 GO:0050436 microfibril binding(GO:0050436)
0.8 3.0 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.6 1.8 GO:0036461 BLOC-2 complex binding(GO:0036461)
0.5 1.5 GO:0015140 malate transmembrane transporter activity(GO:0015140)
0.5 2.3 GO:0004382 guanosine-diphosphatase activity(GO:0004382)
0.5 2.7 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.4 2.7 GO:0004111 creatine kinase activity(GO:0004111)
0.3 2.4 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.3 7.0 GO:0070411 I-SMAD binding(GO:0070411)
0.3 3.0 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.3 1.3 GO:0005118 sevenless binding(GO:0005118)
0.3 6.6 GO:0070410 co-SMAD binding(GO:0070410)
0.3 2.1 GO:0047276 N-acetyllactosaminide 3-alpha-galactosyltransferase activity(GO:0047276)
0.3 0.8 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.3 1.3 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.2 1.8 GO:0070878 primary miRNA binding(GO:0070878)
0.2 6.8 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.2 1.3 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.2 2.1 GO:0005113 patched binding(GO:0005113)
0.2 3.1 GO:0019841 retinol binding(GO:0019841)
0.2 0.5 GO:0033680 ATP-dependent DNA/RNA helicase activity(GO:0033680) triplex DNA binding(GO:0045142)
0.2 1.5 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.2 1.1 GO:1990254 keratin filament binding(GO:1990254)
0.2 1.1 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.2 1.1 GO:0030899 calcium-dependent ATPase activity(GO:0030899)
0.1 0.7 GO:0034604 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.1 1.5 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.1 0.4 GO:0016418 [acyl-carrier-protein] S-malonyltransferase activity(GO:0004314) oleoyl-[acyl-carrier-protein] hydrolase activity(GO:0004320) myristoyl-[acyl-carrier-protein] hydrolase activity(GO:0016295) palmitoyl-[acyl-carrier-protein] hydrolase activity(GO:0016296) acyl-[acyl-carrier-protein] hydrolase activity(GO:0016297) S-acetyltransferase activity(GO:0016418) S-malonyltransferase activity(GO:0016419) malonyltransferase activity(GO:0016420) phosphopantetheine binding(GO:0031177)
0.1 1.0 GO:0030549 acetylcholine receptor activator activity(GO:0030549)
0.1 1.8 GO:0051378 serotonin binding(GO:0051378)
0.1 1.7 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.1 6.2 GO:0003785 actin monomer binding(GO:0003785)
0.1 0.7 GO:0045322 unmethylated CpG binding(GO:0045322)
0.1 0.4 GO:1990699 palmitoleyl hydrolase activity(GO:1990699)
0.1 1.3 GO:0015197 peptide transporter activity(GO:0015197)
0.1 10.3 GO:0042805 actinin binding(GO:0042805)
0.1 4.1 GO:0070064 proline-rich region binding(GO:0070064)
0.1 3.3 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.1 0.5 GO:0034618 arginine binding(GO:0034618)
0.1 1.8 GO:0015037 peptide disulfide oxidoreductase activity(GO:0015037)
0.1 0.3 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.1 1.3 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
0.1 1.0 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.1 1.3 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 2.6 GO:0004190 aspartic-type endopeptidase activity(GO:0004190)
0.1 0.5 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.1 10.4 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.1 0.6 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.1 1.7 GO:0070628 proteasome binding(GO:0070628)
0.1 1.0 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.1 0.3 GO:1990460 leptin receptor binding(GO:1990460)
0.1 7.9 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 2.0 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.1 3.9 GO:0050661 NADP binding(GO:0050661)
0.1 1.4 GO:0004622 lysophospholipase activity(GO:0004622)
0.1 1.0 GO:0030235 nitric-oxide synthase regulator activity(GO:0030235)
0.1 0.6 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1 0.9 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.3 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.0 2.1 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 1.1 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.8 GO:0035198 miRNA binding(GO:0035198)
0.0 0.5 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 2.4 GO:0050699 WW domain binding(GO:0050699)
0.0 1.0 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.3 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.6 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 1.4 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.1 GO:0030350 iron-responsive element binding(GO:0030350)
0.0 0.8 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 1.1 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 1.0 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.6 GO:0003796 lysozyme activity(GO:0003796)
0.0 1.0 GO:0001223 transcription coactivator binding(GO:0001223)
0.0 1.3 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.4 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.0 1.2 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.2 GO:0070883 pre-miRNA binding(GO:0070883)
0.0 2.0 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.8 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.1 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.0 1.2 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.1 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.6 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 2.8 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 4.5 GO:0000287 magnesium ion binding(GO:0000287)
0.0 0.2 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.0 4.0 GO:0051015 actin filament binding(GO:0051015)
0.0 1.0 GO:0004004 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.0 0.5 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 4.5 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 1.0 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 1.0 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0 0.6 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.2 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.3 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.1 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.0 0.7 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.5 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 7.9 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.2 7.3 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.1 8.9 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.1 4.5 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.1 1.9 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.1 2.0 PID S1P S1P4 PATHWAY S1P4 pathway
0.1 3.1 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.1 8.0 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.1 2.7 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.1 4.4 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.1 2.2 PID MYC PATHWAY C-MYC pathway
0.1 8.9 PID AR PATHWAY Coregulation of Androgen receptor activity
0.1 1.7 PID IL5 PATHWAY IL5-mediated signaling events
0.1 2.6 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.1 2.9 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 2.7 ST B CELL ANTIGEN RECEPTOR B Cell Antigen Receptor
0.0 3.3 PID ENDOTHELIN PATHWAY Endothelins
0.0 1.7 PID FOXO PATHWAY FoxO family signaling
0.0 3.3 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 2.7 PID FGF PATHWAY FGF signaling pathway
0.0 0.0 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 1.3 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 6.9 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.2 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 1.1 PID AURORA B PATHWAY Aurora B signaling
0.0 0.5 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 0.3 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 1.3 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.6 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 1.4 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 3.4 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 4.5 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.2 4.6 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.2 6.6 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.2 1.8 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.1 2.2 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1 6.4 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.1 5.1 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.1 3.4 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.1 1.4 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.1 4.4 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 2.2 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.1 0.8 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.1 0.8 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.1 2.1 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.1 1.5 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.1 0.9 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 1.3 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 2.2 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 1.5 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.9 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0 2.0 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.4 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.6 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 1.0 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.4 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.6 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.6 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.3 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 2.7 REACTOME SIGNALING BY FGFR Genes involved in Signaling by FGFR
0.0 0.3 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 2.1 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 1.1 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes