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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Tead3_Tead4

Z-value: 3.77

Motif logo

Transcription factors associated with Tead3_Tead4

Gene Symbol Gene ID Gene Info
ENSMUSG00000002249.22 Tead3
ENSMUSG00000030353.16 Tead4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Tead4mm39_v1_chr6_-_128277701_1282777860.772.0e-15Click!
Tead3mm39_v1_chr17_-_28569574_285696850.709.7e-12Click!

Activity profile of Tead3_Tead4 motif

Sorted Z-values of Tead3_Tead4 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Tead3_Tead4

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr16_+_38182569 54.50 ENSMUST00000023494.13
ENSMUST00000114739.2
popeye domain containing 2
chr10_+_24471340 43.94 ENSMUST00000020171.12
cellular communication network factor 2
chr9_-_66956425 34.87 ENSMUST00000113687.8
ENSMUST00000113693.8
ENSMUST00000113701.8
ENSMUST00000034928.12
ENSMUST00000113685.10
ENSMUST00000030185.5
ENSMUST00000050905.16
ENSMUST00000113705.8
ENSMUST00000113697.8
ENSMUST00000113707.9
tropomyosin 1, alpha
chr10_+_53213763 29.94 ENSMUST00000219491.2
ENSMUST00000163319.9
ENSMUST00000220197.2
ENSMUST00000046221.8
ENSMUST00000218468.2
ENSMUST00000219921.2
phospholamban
chr18_+_23548534 27.59 ENSMUST00000221880.2
ENSMUST00000220904.2
ENSMUST00000047954.15
dystrobrevin alpha
chr15_+_6416229 26.04 ENSMUST00000110664.9
ENSMUST00000110663.9
ENSMUST00000161812.8
ENSMUST00000160134.8
disabled 2, mitogen-responsive phosphoprotein
chr11_-_100861713 25.53 ENSMUST00000060792.6
caveolae associated 1
chr8_+_123912976 23.41 ENSMUST00000019422.6
dipeptidase 1
chr8_-_62213100 21.59 ENSMUST00000121493.9
palladin, cytoskeletal associated protein
chr2_+_25346841 21.36 ENSMUST00000114265.9
ENSMUST00000102918.3
chloride intracellular channel 3
chr14_-_55231998 21.23 ENSMUST00000227518.2
ENSMUST00000226424.2
ENSMUST00000153783.2
ENSMUST00000102803.11
ENSMUST00000168485.8
myosin, heavy polypeptide 7, cardiac muscle, beta
chr6_-_67512768 20.30 ENSMUST00000058178.6
tumor-associated calcium signal transducer 2
chr1_+_135764092 20.13 ENSMUST00000188028.7
ENSMUST00000178204.8
ENSMUST00000190451.7
ENSMUST00000189732.7
ENSMUST00000189355.7
troponin T2, cardiac
chr17_+_71326510 19.89 ENSMUST00000073211.13
ENSMUST00000024847.14
myomesin 1
chr1_+_51328265 19.14 ENSMUST00000051572.8
caveolae associated 2
chr7_-_33832640 19.08 ENSMUST00000038537.9
WT1-interacting protein
chr1_+_189460461 18.92 ENSMUST00000097442.9
protein tyrosine phosphatase, non-receptor type 14
chr6_-_128277701 18.90 ENSMUST00000143004.2
ENSMUST00000006311.13
ENSMUST00000112157.4
ENSMUST00000133118.2
TEA domain family member 4
chr6_+_17307038 18.68 ENSMUST00000123439.8
caveolin 1, caveolae protein
chr17_+_71326542 18.25 ENSMUST00000179759.3
myomesin 1
chr18_+_23548455 17.42 ENSMUST00000115832.4
dystrobrevin alpha
chr9_-_107482494 17.09 ENSMUST00000102529.10
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
chr17_+_35960600 16.81 ENSMUST00000171166.3
surfactant associated 2
chr14_-_55204092 16.62 ENSMUST00000081857.14
myosin, heavy polypeptide 6, cardiac muscle, alpha
chr14_-_55204054 16.52 ENSMUST00000226297.2
myosin, heavy polypeptide 6, cardiac muscle, alpha
chr6_+_17306334 16.09 ENSMUST00000007799.13
ENSMUST00000115456.6
caveolin 1, caveolae protein
chr17_-_71309815 16.01 ENSMUST00000123686.8
myosin, light chain 12A, regulatory, non-sarcomeric
chr11_+_98303287 15.99 ENSMUST00000058295.6
erb-b2 receptor tyrosine kinase 2
chr13_-_113182891 15.87 ENSMUST00000231962.2
ENSMUST00000022282.6
glutathione peroxidase 8 (putative)
chr9_-_107486381 15.59 ENSMUST00000102531.7
ENSMUST00000102530.8
ENSMUST00000195057.2
ENSMUST00000102532.10
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
chr14_-_54815000 14.91 ENSMUST00000054487.10
ajuba LIM protein
chr1_-_134731516 14.49 ENSMUST00000238280.2
protein phosphatase 1, regulatory subunit 12B
chr10_-_22696025 14.42 ENSMUST00000218002.2
ENSMUST00000049930.9
transcription factor 21
chr6_+_17306379 14.38 ENSMUST00000115455.3
caveolin 1, caveolae protein
chr7_-_44174065 14.38 ENSMUST00000165208.4
myosin binding protein C, fast-type
chr3_-_151971391 14.24 ENSMUST00000199470.5
ENSMUST00000200589.5
nexilin
chr15_+_6416079 14.07 ENSMUST00000080880.12
disabled 2, mitogen-responsive phosphoprotein
chr5_+_31274046 14.00 ENSMUST00000013771.15
tripartite motif-containing 54
chr5_+_31274064 13.84 ENSMUST00000202769.2
tripartite motif-containing 54
chr6_+_113435716 13.56 ENSMUST00000203661.3
ENSMUST00000204774.3
ENSMUST00000053569.7
ENSMUST00000101065.8
interleukin 17 receptor E
chr1_+_45350698 13.51 ENSMUST00000087883.13
collagen, type III, alpha 1
chr1_-_72914036 13.38 ENSMUST00000027377.9
insulin-like growth factor binding protein 5
chr14_-_55204383 13.21 ENSMUST00000111456.2
myosin, heavy polypeptide 6, cardiac muscle, alpha
chr4_+_148070245 13.20 ENSMUST00000103231.5
natriuretic peptide type B
chr13_+_49761506 13.10 ENSMUST00000021822.7
osteoglycin
chr6_+_122490534 12.79 ENSMUST00000032210.14
ENSMUST00000148517.8
microfibrillar associated protein 5
chr6_+_17306414 12.54 ENSMUST00000150901.2
caveolin 1, caveolae protein
chr9_-_107482462 12.33 ENSMUST00000194433.6
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
chr10_-_78427721 12.26 ENSMUST00000040580.7
synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
chr5_-_137312424 12.19 ENSMUST00000199121.2
thyroid hormone receptor interactor 6
chr10_+_93476903 12.08 ENSMUST00000020204.5
netrin 4
chr6_+_29433247 12.08 ENSMUST00000101617.9
ENSMUST00000065090.8
filamin C, gamma
chr6_+_146789978 12.04 ENSMUST00000016631.14
ENSMUST00000203730.3
ENSMUST00000111623.9
PTPRF interacting protein, binding protein 1 (liprin beta 1)
chr1_+_170983081 11.95 ENSMUST00000111334.2
myelin protein zero
chr5_+_67125759 11.91 ENSMUST00000238993.2
ENSMUST00000038188.14
LIM and calponin homology domains 1
chr6_+_122490635 11.85 ENSMUST00000142896.8
ENSMUST00000121656.2
microfibrillar associated protein 5
chr17_+_47747657 11.76 ENSMUST00000150819.3
expressed sequence AI661453
chr18_-_35855383 11.63 ENSMUST00000133064.8
endothelial cell surface expressed chemotaxis and apoptosis regulator
chr17_-_28569574 11.47 ENSMUST00000114799.8
ENSMUST00000219703.3
TEA domain family member 3
chr17_+_47747540 11.39 ENSMUST00000037701.13
expressed sequence AI661453
chr6_+_122490577 11.18 ENSMUST00000118626.8
microfibrillar associated protein 5
chr2_+_90948481 11.15 ENSMUST00000137942.8
ENSMUST00000111430.10
ENSMUST00000169776.2
myosin binding protein C, cardiac
chr8_-_123278054 10.95 ENSMUST00000156333.9
ENSMUST00000067252.14
piezo-type mechanosensitive ion channel component 1
chr2_+_129854256 10.68 ENSMUST00000110299.3
transglutaminase 3, E polypeptide
chr5_-_18054702 10.68 ENSMUST00000165232.8
CD36 molecule
chr15_+_78726824 10.64 ENSMUST00000059619.3
CDC42 effector protein (Rho GTPase binding) 1
chr12_+_75355082 10.59 ENSMUST00000118602.8
ENSMUST00000118966.8
ENSMUST00000055390.6
ras homolog family member J
chr11_-_101061153 10.52 ENSMUST00000123864.2
pleckstrin homology domain containing, family H (with MyTH4 domain) member 3
chr6_-_119173348 10.51 ENSMUST00000187474.7
ENSMUST00000187940.7
calcium channel, voltage-dependent, L type, alpha 1C subunit
chr14_-_55204023 10.46 ENSMUST00000124930.8
myosin, heavy polypeptide 6, cardiac muscle, alpha
chr4_+_94627755 10.40 ENSMUST00000071168.6
TEK receptor tyrosine kinase
chr5_-_18054781 10.38 ENSMUST00000170051.8
CD36 molecule
chr2_+_74522258 9.94 ENSMUST00000061745.5
homeobox D10
chr19_-_23425757 9.88 ENSMUST00000036069.8
MAM domain containing 2
chrX_+_132809166 9.80 ENSMUST00000033606.15
sushi-repeat-containing protein, X-linked 2
chr14_+_30601157 9.78 ENSMUST00000040715.8
musculoskeletal, embryonic nuclear protein 1
chr8_-_124621483 9.73 ENSMUST00000034453.6
ENSMUST00000212584.2
actin, alpha 1, skeletal muscle
chr12_-_98703664 9.71 ENSMUST00000170188.8
protein tyrosine phosphatase, non-receptor type 21
chr4_+_94627513 9.70 ENSMUST00000073939.13
ENSMUST00000102798.8
TEK receptor tyrosine kinase
chr19_+_53781721 9.63 ENSMUST00000162910.2
RNA binding motif protein 20
chr15_-_12549350 9.62 ENSMUST00000190929.2
PDZ domain containing 2
chr11_-_32172233 9.59 ENSMUST00000150381.2
ENSMUST00000144902.2
ENSMUST00000020524.15
rhomboid 5 homolog 1
chr10_-_63039709 9.58 ENSMUST00000095580.3
myopalladin
chr3_-_145355725 9.45 ENSMUST00000029846.5
cellular communication network factor 1
chr4_+_134042423 9.37 ENSMUST00000105875.8
ENSMUST00000030638.7
tripartite motif-containing 63
chr19_-_36097233 9.23 ENSMUST00000025718.10
ankyrin repeat domain 1 (cardiac muscle)
chr11_-_115704447 9.20 ENSMUST00000041684.11
ENSMUST00000156812.2
CASK-interacting protein 2
chr1_-_74040723 9.17 ENSMUST00000190389.7
tensin 1
chr3_-_129548954 9.10 ENSMUST00000029653.7
epidermal growth factor
chr5_+_104607316 9.09 ENSMUST00000086831.4
polycystin 2, transient receptor potential cation channel
chr5_-_69699965 9.06 ENSMUST00000031045.10
Yip1 domain family, member 7
chr2_-_148285450 9.04 ENSMUST00000099269.4
CD93 antigen
chr1_+_135252508 9.04 ENSMUST00000059352.3
leiomodin 1 (smooth muscle)
chr11_+_70591299 9.00 ENSMUST00000152618.9
ENSMUST00000102554.8
ENSMUST00000094499.11
ENSMUST00000072187.12
ENSMUST00000137119.3
kinesin family member 1C
chr2_-_181313415 8.89 ENSMUST00000054491.6
SRY (sex determining region Y)-box 18
chr19_+_8966641 8.82 ENSMUST00000092956.4
ENSMUST00000092955.11
AHNAK nucleoprotein (desmoyokin)
chr8_-_48443525 8.75 ENSMUST00000057561.9
WW, C2 and coiled-coil domain containing 2
chr11_+_77353218 8.72 ENSMUST00000102493.8
coronin 6
chr3_-_57483175 8.68 ENSMUST00000029380.14
WW domain containing transcription regulator 1
chrX_+_132809189 8.66 ENSMUST00000113304.2
sushi-repeat-containing protein, X-linked 2
chr3_-_92734546 8.59 ENSMUST00000072363.5
keratinocyte expressed, proline-rich
chr11_+_96214078 8.53 ENSMUST00000093944.10
homeobox B3
chr5_-_103777145 8.40 ENSMUST00000031263.2
solute carrier family 10 (sodium/bile acid cotransporter family), member 6
chr9_-_58065800 8.36 ENSMUST00000168864.4
immunoglobulin superfamily containing leucine-rich repeat
chr8_-_86091970 8.33 ENSMUST00000121972.8
myosin light chain kinase 3
chr7_-_65020655 8.14 ENSMUST00000032729.8
tight junction protein 1
chr3_-_57483330 8.14 ENSMUST00000120977.2
WW domain containing transcription regulator 1
chr2_+_72115981 8.04 ENSMUST00000090824.12
ENSMUST00000135469.8
mitogen-activated protein kinase kinase kinase 20
chr10_+_32959472 7.99 ENSMUST00000095762.5
ENSMUST00000218281.2
ENSMUST00000217779.2
ENSMUST00000219665.2
ENSMUST00000219931.2
triadin
chr10_+_5543769 7.95 ENSMUST00000051809.10
myc target 1
chr7_+_43441315 7.79 ENSMUST00000005891.7
kallikrein related-peptidase 9
chr17_-_28569721 7.72 ENSMUST00000156862.3
TEA domain family member 3
chr13_-_63006176 7.69 ENSMUST00000021907.9
fructose bisphosphatase 2
chr15_+_101308935 7.63 ENSMUST00000147662.8
keratin 7
chr7_-_30754223 7.55 ENSMUST00000206012.2
ENSMUST00000108110.5
FXYD domain-containing ion transport regulator 1
chr14_-_32407203 7.52 ENSMUST00000096038.4
RIKEN cDNA 3425401B19 gene
chr5_-_69699932 7.48 ENSMUST00000202423.2
Yip1 domain family, member 7
chr7_+_128125339 7.44 ENSMUST00000033136.9
BCL2-associated athanogene 3
chr2_-_60383647 7.43 ENSMUST00000112525.5
phospholipase A2 receptor 1
chr2_-_17465410 7.42 ENSMUST00000145492.2
nebulette
chr6_-_37419030 7.38 ENSMUST00000041093.6
cAMP responsive element binding protein 3-like 2
chr1_-_153061758 7.34 ENSMUST00000185356.7
laminin, gamma 2
chr7_-_30754193 7.34 ENSMUST00000205778.2
FXYD domain-containing ion transport regulator 1
chr3_+_19698631 7.32 ENSMUST00000029139.9
tripartite motif-containing 55
chr5_-_24806960 7.26 ENSMUST00000030791.12
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
chr5_+_53206688 7.24 ENSMUST00000094787.8
solute carrier family 34 (sodium phosphate), member 2
chr11_-_5753693 7.24 ENSMUST00000020768.4
phosphoglycerate mutase 2
chr17_-_24863907 7.21 ENSMUST00000234505.2
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2
chr11_+_96740689 7.21 ENSMUST00000018816.14
coatomer protein complex, subunit zeta 2
chr2_+_90865958 7.20 ENSMUST00000111445.10
ENSMUST00000111446.10
ENSMUST00000050323.6
receptor-associated protein of the synapse
chr8_-_86091946 7.20 ENSMUST00000034133.14
myosin light chain kinase 3
chr19_-_57185928 7.16 ENSMUST00000111544.8
actin-binding LIM protein 1
chr9_+_102594867 7.14 ENSMUST00000035121.14
angiomotin-like 2
chr2_+_160722562 7.11 ENSMUST00000109456.9
lipin 3
chr7_-_30754240 7.08 ENSMUST00000206860.2
ENSMUST00000071697.11
FXYD domain-containing ion transport regulator 1
chr18_+_50164043 7.05 ENSMUST00000145726.2
ENSMUST00000128377.2
tumor necrosis factor, alpha-induced protein 8
chr14_-_57983511 7.04 ENSMUST00000173990.8
ENSMUST00000022531.14
large tumor suppressor 2
chr1_+_43769750 6.97 ENSMUST00000027217.9
ECRG4 augurin precursor
chr16_-_95387444 6.93 ENSMUST00000233269.2
ETS transcription factor
chr17_+_88933957 6.92 ENSMUST00000163588.8
ENSMUST00000064035.13
stonin 1
chr9_+_69361348 6.87 ENSMUST00000134907.8
annexin A2
chr15_-_12549963 6.87 ENSMUST00000189324.2
PDZ domain containing 2
chr13_+_112600604 6.80 ENSMUST00000183663.8
ENSMUST00000184311.8
ENSMUST00000183886.8
interleukin 6 signal transducer
chr12_+_85793313 6.76 ENSMUST00000040461.4
feline leukemia virus subgroup C cellular receptor 2
chr7_+_130247912 6.75 ENSMUST00000207549.2
ENSMUST00000209108.2
transforming, acidic coiled-coil containing protein 2
chr8_-_105350898 6.74 ENSMUST00000212882.2
ENSMUST00000163783.4
cadherin 16
chr16_-_38620688 6.70 ENSMUST00000057767.6
uroplakin 1B
chr6_-_142453531 6.67 ENSMUST00000134191.3
ENSMUST00000239397.2
ENSMUST00000239395.2
ENSMUST00000032373.12
lactate dehydrogenase B
chr8_+_94863825 6.60 ENSMUST00000034207.8
metallothionein 4
chr3_-_116601451 6.59 ENSMUST00000159670.3
amylo-1,6-glucosidase, 4-alpha-glucanotransferase
chr18_+_23548192 6.58 ENSMUST00000222515.2
dystrobrevin alpha
chr6_-_52217821 6.57 ENSMUST00000121043.2
homeobox A10
chr6_+_145879839 6.51 ENSMUST00000032383.14
sarcospan
chr1_+_135693818 6.47 ENSMUST00000038945.6
pleckstrin homology like domain, family A, member 3
chr5_+_67055753 6.42 ENSMUST00000122812.5
ENSMUST00000117601.8
LIM and calponin homology domains 1
chr9_-_8004586 6.41 ENSMUST00000086580.12
ENSMUST00000065353.13
yes-associated protein 1
chr13_-_95661726 6.37 ENSMUST00000022185.10
coagulation factor II (thrombin) receptor-like 1
chr11_+_100306523 6.34 ENSMUST00000001595.10
ENSMUST00000107400.3
FK506 binding protein 10
chr6_+_34575435 6.29 ENSMUST00000079391.10
ENSMUST00000142512.8
ENSMUST00000115027.8
ENSMUST00000115026.8
caldesmon 1
chr14_-_45715308 6.28 ENSMUST00000141424.2
fermitin family member 2
chr15_-_42540363 6.28 ENSMUST00000022921.7
angiopoietin 1
chr4_+_154321982 6.25 ENSMUST00000152159.8
multiple EGF-like-domains 6
chr19_-_57185861 6.25 ENSMUST00000111550.8
actin-binding LIM protein 1
chr1_-_66984178 6.23 ENSMUST00000027151.12
myosin, light polypeptide 1
chr1_+_75362187 6.23 ENSMUST00000137868.8
SPEG complex locus
chr3_-_101017594 6.20 ENSMUST00000102694.4
prostaglandin F2 receptor negative regulator
chr17_+_88933997 6.19 ENSMUST00000150023.2
stonin 1
chrX_+_72030945 6.15 ENSMUST00000164800.8
ENSMUST00000114546.9
zinc finger protein 185
chr14_+_101967343 6.12 ENSMUST00000100337.10
LIM domain only 7
chr9_-_58943670 6.10 ENSMUST00000214547.2
ENSMUST00000068664.7
neogenin
chr4_+_118286898 6.08 ENSMUST00000067896.4
elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 1
chr8_-_95644639 6.01 ENSMUST00000077955.6
coiled-coil domain containing 102A
chr1_-_66984521 6.00 ENSMUST00000160100.2
myosin, light polypeptide 1
chr3_-_116601700 5.99 ENSMUST00000159742.8
amylo-1,6-glucosidase, 4-alpha-glucanotransferase
chr10_+_21868114 5.96 ENSMUST00000150089.8
ENSMUST00000100036.10
serum/glucocorticoid regulated kinase 1
chr7_-_30754792 5.88 ENSMUST00000206328.2
FXYD domain-containing ion transport regulator 1
chr4_-_58206596 5.85 ENSMUST00000042850.9
sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
chr9_-_18585826 5.84 ENSMUST00000208663.2
mucin 16
chr3_-_154760978 5.82 ENSMUST00000064076.6
TNNI3 interacting kinase
chr3_-_103645311 5.78 ENSMUST00000029440.10
olfactomedin-like 3
chr19_-_57185988 5.78 ENSMUST00000099294.9
actin-binding LIM protein 1
chr12_+_119354110 5.75 ENSMUST00000222058.2
metastasis associated in colon cancer 1
chr4_+_97665992 5.73 ENSMUST00000107062.9
ENSMUST00000052018.12
ENSMUST00000107057.8
nuclear factor I/A
chr7_+_144854542 5.72 ENSMUST00000033386.12
MAS-related GPR, member F
chr17_-_71309012 5.71 ENSMUST00000128179.2
ENSMUST00000150456.2
ENSMUST00000233357.2
ENSMUST00000233417.2
myosin, light chain 12A, regulatory, non-sarcomeric
predicted gene, 49909
chr9_+_102594474 5.67 ENSMUST00000153911.2
angiomotin-like 2
chr19_-_57185808 5.66 ENSMUST00000111546.8
actin-binding LIM protein 1
chr9_-_44624496 5.61 ENSMUST00000144251.8
ENSMUST00000156918.8
pleckstrin homology like domain, family B, member 1
chr17_+_75772475 5.60 ENSMUST00000095204.6
RAS, guanyl releasing protein 3
chr1_+_12762501 5.53 ENSMUST00000177608.8
ENSMUST00000180062.8
sulfatase 1
chr19_+_45006552 5.40 ENSMUST00000237043.2
ENSMUST00000178087.3
leucine zipper, putative tumor suppressor 2
chr9_-_77255099 5.31 ENSMUST00000184138.8
ENSMUST00000184006.8
ENSMUST00000185144.8
ENSMUST00000034910.16
muscular LMNA-interacting protein
chr2_+_155118217 5.27 ENSMUST00000029128.4
microtubule-associated protein 1 light chain 3 alpha
chr4_+_57637817 5.22 ENSMUST00000150412.4
paralemmin A kinase anchor protein
chr7_+_141048722 5.22 ENSMUST00000058746.7
CD151 antigen
chr14_+_47120311 5.18 ENSMUST00000022386.15
ENSMUST00000228404.2
ENSMUST00000100672.11
sterile alpha motif domain containing 4
chr5_-_135518098 5.16 ENSMUST00000201998.2
huntingtin interacting protein 1
chr8_-_105350881 5.14 ENSMUST00000211903.2
cadherin 16
chr8_-_37081091 5.12 ENSMUST00000033923.14
deleted in liver cancer 1
chr1_+_40619215 5.12 ENSMUST00000027233.9
solute carrier family 9 (sodium/hydrogen exchanger), member 4

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
14.2 56.8 GO:0007522 visceral muscle development(GO:0007522)
10.9 54.5 GO:0060931 sinoatrial node cell development(GO:0060931)
10.3 61.7 GO:1900085 negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609)
7.1 21.2 GO:0014728 regulation of the force of skeletal muscle contraction(GO:0014728) regulation of skeletal muscle contraction by chemo-mechanical energy conversion(GO:0014862)
6.7 40.1 GO:0035026 leading edge cell differentiation(GO:0035026)
6.4 25.5 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
5.9 23.4 GO:0016999 antibiotic metabolic process(GO:0016999)
5.8 34.9 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
5.3 26.4 GO:0048014 Tie signaling pathway(GO:0048014)
5.0 20.1 GO:0032972 regulation of muscle filament sliding speed(GO:0032972)
4.8 14.4 GO:0060435 bronchiole development(GO:0060435)
4.5 44.6 GO:0035331 negative regulation of hippo signaling(GO:0035331)
4.2 21.1 GO:0070543 response to linoleic acid(GO:0070543)
4.1 12.2 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
3.9 15.5 GO:0048769 sarcomerogenesis(GO:0048769)
3.8 19.0 GO:0090191 negative regulation of branching involved in ureteric bud morphogenesis(GO:0090191)
3.8 18.9 GO:0001830 trophectodermal cell fate commitment(GO:0001830)
3.7 63.7 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
3.3 13.4 GO:0014734 skeletal muscle hypertrophy(GO:0014734)
3.2 9.7 GO:0030240 skeletal muscle thin filament assembly(GO:0030240)
3.2 16.0 GO:0033088 negative regulation of immature T cell proliferation in thymus(GO:0033088) estrous cycle(GO:0044849)
3.1 9.4 GO:0014878 response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
3.0 9.1 GO:0009726 detection of nodal flow(GO:0003127) detection of endogenous stimulus(GO:0009726)
3.0 29.9 GO:0086023 adrenergic receptor signaling pathway involved in heart process(GO:0086023)
2.9 8.6 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
2.7 13.5 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
2.7 8.1 GO:0018146 keratan sulfate biosynthetic process(GO:0018146)
2.5 27.9 GO:1903797 positive regulation of sodium ion export(GO:1903275) positive regulation of sodium ion export from cell(GO:1903278) positive regulation of inorganic anion transmembrane transport(GO:1903797)
2.5 12.3 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
2.3 7.0 GO:0001828 inner cell mass cellular morphogenesis(GO:0001828)
2.3 23.2 GO:0072307 metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
2.3 6.8 GO:0070104 negative regulation of interleukin-6-mediated signaling pathway(GO:0070104)
2.2 10.9 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
2.2 23.8 GO:0048739 cardiac muscle fiber development(GO:0048739)
2.1 6.4 GO:0043311 positive regulation of eosinophil degranulation(GO:0043311) regulation of neutrophil mediated cytotoxicity(GO:0070948) regulation of neutrophil mediated killing of symbiont cell(GO:0070949) positive regulation of renin secretion into blood stream(GO:1900135) positive regulation of eosinophil activation(GO:1902568)
2.0 8.1 GO:0008582 regulation of synaptic growth at neuromuscular junction(GO:0008582)
1.9 11.7 GO:0032804 negative regulation of low-density lipoprotein particle receptor catabolic process(GO:0032804)
1.9 7.7 GO:0046351 disaccharide biosynthetic process(GO:0046351)
1.8 8.9 GO:0048866 stem cell fate specification(GO:0048866)
1.7 8.4 GO:1905171 protein localization to phagocytic vesicle(GO:1905161) regulation of protein localization to phagocytic vesicle(GO:1905169) positive regulation of protein localization to phagocytic vesicle(GO:1905171)
1.6 19.2 GO:0055059 asymmetric neuroblast division(GO:0055059)
1.5 4.6 GO:1904582 positive regulation of intracellular mRNA localization(GO:1904582)
1.5 4.6 GO:0010710 regulation of collagen catabolic process(GO:0010710)
1.5 12.1 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
1.5 7.4 GO:0090403 oxidative stress-induced premature senescence(GO:0090403)
1.4 7.2 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
1.4 4.3 GO:0021629 olfactory nerve morphogenesis(GO:0021627) olfactory nerve structural organization(GO:0021629)
1.4 8.5 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)
1.4 21.7 GO:0031272 regulation of pseudopodium assembly(GO:0031272)
1.3 8.0 GO:0090158 endoplasmic reticulum membrane organization(GO:0090158)
1.3 35.8 GO:0097435 fibril organization(GO:0097435)
1.3 18.5 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
1.3 2.6 GO:0072199 mesenchymal cell proliferation involved in ureter development(GO:0072198) regulation of mesenchymal cell proliferation involved in ureter development(GO:0072199) positive regulation of mesenchymal cell proliferation involved in ureter development(GO:2000729)
1.3 9.1 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
1.3 5.2 GO:2000588 positive regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000588)
1.3 1.3 GO:0051124 synaptic growth at neuromuscular junction(GO:0051124)
1.2 9.8 GO:1902732 positive regulation of chondrocyte proliferation(GO:1902732)
1.2 7.2 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
1.2 8.3 GO:0098912 membrane depolarization during atrial cardiac muscle cell action potential(GO:0098912)
1.2 6.9 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
1.2 4.6 GO:1902396 protein localization to bicellular tight junction(GO:1902396)
1.1 4.6 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
1.1 3.4 GO:0007228 positive regulation of hh target transcription factor activity(GO:0007228)
1.1 5.5 GO:0060685 regulation of prostatic bud formation(GO:0060685) negative regulation of prostatic bud formation(GO:0060686)
1.1 4.3 GO:0051387 negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
1.1 4.3 GO:0021502 neural fold elevation formation(GO:0021502)
1.0 7.3 GO:0003219 cardiac right ventricle formation(GO:0003219)
1.0 2.9 GO:0048320 axial mesoderm formation(GO:0048320)
1.0 10.6 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
1.0 4.8 GO:1903847 regulation of aorta morphogenesis(GO:1903847) positive regulation of aorta morphogenesis(GO:1903849)
0.9 21.6 GO:0003334 keratinocyte development(GO:0003334) positive regulation of podosome assembly(GO:0071803)
0.9 4.4 GO:0031394 positive regulation of prostaglandin biosynthetic process(GO:0031394) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.9 3.5 GO:1904428 negative regulation of tubulin deacetylation(GO:1904428)
0.9 2.6 GO:0061144 alveolar secondary septum development(GO:0061144)
0.9 18.9 GO:0001946 lymphangiogenesis(GO:0001946)
0.8 9.9 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.8 7.2 GO:0071340 skeletal muscle acetylcholine-gated channel clustering(GO:0071340)
0.8 11.9 GO:0045217 cell-cell junction maintenance(GO:0045217)
0.8 9.6 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.8 7.9 GO:0002072 optic cup morphogenesis involved in camera-type eye development(GO:0002072)
0.8 1.5 GO:0002085 inhibition of neuroepithelial cell differentiation(GO:0002085) negative regulation of auditory receptor cell differentiation(GO:0045608)
0.7 4.5 GO:0032290 peripheral nervous system myelin formation(GO:0032290)
0.7 4.4 GO:0038031 non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.7 2.2 GO:2000328 regulation of T-helper 17 cell lineage commitment(GO:2000328)
0.7 13.2 GO:0035815 positive regulation of renal sodium excretion(GO:0035815)
0.7 2.1 GO:0048549 positive regulation of pinocytosis(GO:0048549)
0.7 15.3 GO:0070831 basement membrane assembly(GO:0070831)
0.7 17.1 GO:0035329 hippo signaling(GO:0035329)
0.6 5.8 GO:0045409 negative regulation of interleukin-6 biosynthetic process(GO:0045409)
0.6 2.5 GO:0042360 vitamin E metabolic process(GO:0042360)
0.6 17.2 GO:0044247 glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.6 6.7 GO:0019244 lactate biosynthetic process from pyruvate(GO:0019244)
0.6 4.7 GO:1904220 regulation of serine C-palmitoyltransferase activity(GO:1904220)
0.6 1.7 GO:1904117 response to vasopressin(GO:1904116) cellular response to vasopressin(GO:1904117)
0.6 5.0 GO:0007406 negative regulation of neuroblast proliferation(GO:0007406)
0.5 3.8 GO:1900122 positive regulation of receptor binding(GO:1900122)
0.5 9.3 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.5 2.1 GO:0010735 positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation(GO:0003257) positive regulation of transcription via serum response element binding(GO:0010735)
0.5 13.3 GO:2000353 positive regulation of endothelial cell apoptotic process(GO:2000353)
0.5 11.6 GO:0030953 interkinetic nuclear migration(GO:0022027) astral microtubule organization(GO:0030953)
0.5 9.2 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.5 6.1 GO:0034625 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.5 6.5 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.5 17.8 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.5 4.4 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816)
0.5 18.1 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.5 1.4 GO:2001176 mediator complex assembly(GO:0036034) regulation of mediator complex assembly(GO:2001176) positive regulation of mediator complex assembly(GO:2001178)
0.5 0.9 GO:0033629 negative regulation of cell adhesion mediated by integrin(GO:0033629)
0.5 1.4 GO:0060722 spongiotrophoblast cell proliferation(GO:0060720) cell proliferation involved in embryonic placenta development(GO:0060722)
0.5 8.1 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.4 1.7 GO:0033575 protein glycosylation at cell surface(GO:0033575) protein galactosylation at cell surface(GO:0033580) protein galactosylation(GO:0042125)
0.4 4.3 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
0.4 2.2 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.4 5.1 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.4 1.7 GO:0060750 epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750) branch elongation involved in mammary gland duct branching(GO:0060751)
0.4 4.0 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.4 15.6 GO:0031424 keratinization(GO:0031424)
0.4 4.7 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.4 7.4 GO:0035428 hexose transmembrane transport(GO:0035428)
0.4 6.1 GO:0048681 negative regulation of axon regeneration(GO:0048681)
0.4 1.1 GO:0019918 peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918)
0.4 21.6 GO:0050919 negative chemotaxis(GO:0050919)
0.3 7.4 GO:0097201 negative regulation of transcription from RNA polymerase II promoter in response to stress(GO:0097201)
0.3 3.3 GO:0010454 negative regulation of cell fate commitment(GO:0010454) intestinal epithelial cell development(GO:0060576)
0.3 5.3 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.3 1.0 GO:1904630 negative regulation of interleukin-12 biosynthetic process(GO:0045083) response to diterpene(GO:1904629) cellular response to diterpene(GO:1904630) response to glucoside(GO:1904631) cellular response to glucoside(GO:1904632)
0.3 1.9 GO:0090306 spindle assembly involved in meiosis(GO:0090306)
0.3 1.2 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
0.3 5.8 GO:0086069 bundle of His cell to Purkinje myocyte communication(GO:0086069)
0.3 1.8 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.3 2.0 GO:0030035 microspike assembly(GO:0030035)
0.3 5.1 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.3 2.0 GO:0002003 angiotensin maturation(GO:0002003)
0.3 3.9 GO:0006751 glutathione catabolic process(GO:0006751)
0.3 1.9 GO:0042938 dipeptide transport(GO:0042938)
0.3 3.8 GO:0030853 negative regulation of granulocyte differentiation(GO:0030853)
0.3 29.9 GO:0030032 lamellipodium assembly(GO:0030032)
0.3 1.4 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.3 12.8 GO:0000186 activation of MAPKK activity(GO:0000186)
0.3 1.3 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.3 1.5 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.3 1.3 GO:0048069 eye pigmentation(GO:0048069)
0.2 7.2 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.2 6.2 GO:0034389 lipid particle organization(GO:0034389)
0.2 1.0 GO:0017187 peptidyl-glutamic acid carboxylation(GO:0017187)
0.2 1.0 GO:0009436 glyoxylate catabolic process(GO:0009436)
0.2 1.0 GO:0042723 thiamine metabolic process(GO:0006772) thiamine-containing compound metabolic process(GO:0042723)
0.2 6.3 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.2 7.2 GO:0032292 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.2 1.6 GO:0007527 adult somatic muscle development(GO:0007527)
0.2 0.9 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.2 2.7 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.2 4.2 GO:0048642 negative regulation of skeletal muscle tissue development(GO:0048642)
0.2 6.4 GO:0097320 membrane tubulation(GO:0097320)
0.2 2.5 GO:0032836 glomerular basement membrane development(GO:0032836)
0.2 0.8 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.2 8.9 GO:0014741 negative regulation of muscle hypertrophy(GO:0014741)
0.2 6.6 GO:0046686 response to cadmium ion(GO:0046686)
0.2 1.2 GO:0034184 positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184) protein localization to site of double-strand break(GO:1990166)
0.2 1.7 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.2 3.0 GO:0033147 negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.2 7.8 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.2 6.6 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.2 1.4 GO:0009253 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.2 10.7 GO:0045010 actin nucleation(GO:0045010)
0.2 6.9 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.2 11.4 GO:0032611 interleukin-1 beta production(GO:0032611)
0.2 1.8 GO:2000507 positive regulation of energy homeostasis(GO:2000507)
0.2 5.7 GO:0060074 synapse maturation(GO:0060074)
0.2 0.6 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.2 9.1 GO:0010761 fibroblast migration(GO:0010761)
0.2 0.9 GO:0055118 negative regulation of cardiac muscle contraction(GO:0055118)
0.2 9.6 GO:0033120 positive regulation of RNA splicing(GO:0033120)
0.2 1.2 GO:0051451 myoblast migration(GO:0051451)
0.2 1.2 GO:0006166 purine ribonucleoside salvage(GO:0006166)
0.1 6.2 GO:0055013 cardiac muscle cell development(GO:0055013)
0.1 1.8 GO:0061436 establishment of skin barrier(GO:0061436)
0.1 8.3 GO:0048747 muscle fiber development(GO:0048747)
0.1 0.6 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.1 0.5 GO:2000620 innate vocalization behavior(GO:0098582) positive regulation of histone H4-K16 acetylation(GO:2000620)
0.1 0.5 GO:0010286 heat acclimation(GO:0010286)
0.1 0.5 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.1 26.1 GO:0008360 regulation of cell shape(GO:0008360)
0.1 0.8 GO:0051013 microtubule severing(GO:0051013)
0.1 1.7 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1 0.6 GO:0002084 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.1 0.5 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.1 2.6 GO:0002230 positive regulation of defense response to virus by host(GO:0002230)
0.1 7.1 GO:0019432 triglyceride biosynthetic process(GO:0019432)
0.1 3.2 GO:0042036 negative regulation of cytokine biosynthetic process(GO:0042036)
0.1 2.8 GO:0006744 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.1 1.8 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.1 6.5 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.1 5.7 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.1 3.7 GO:0006825 copper ion transport(GO:0006825)
0.1 1.7 GO:0003215 cardiac right ventricle morphogenesis(GO:0003215)
0.1 0.6 GO:0060178 regulation of exocyst localization(GO:0060178)
0.1 1.0 GO:0071526 semaphorin-plexin signaling pathway(GO:0071526)
0.1 1.0 GO:0021779 oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.1 2.1 GO:0042118 endothelial cell activation(GO:0042118)
0.1 0.7 GO:0043578 nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.1 6.3 GO:0006940 regulation of smooth muscle contraction(GO:0006940)
0.1 0.1 GO:1901668 regulation of superoxide dismutase activity(GO:1901668)
0.1 0.3 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.1 8.7 GO:0060048 cardiac muscle contraction(GO:0060048)
0.1 5.2 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.1 0.8 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.1 1.3 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 1.6 GO:0050891 multicellular organismal water homeostasis(GO:0050891)
0.1 2.4 GO:0051496 positive regulation of stress fiber assembly(GO:0051496)
0.1 5.9 GO:1900181 negative regulation of protein localization to nucleus(GO:1900181)
0.1 0.8 GO:0000022 mitotic spindle elongation(GO:0000022) mitotic spindle midzone assembly(GO:0051256)
0.1 8.5 GO:0031032 actomyosin structure organization(GO:0031032)
0.1 1.4 GO:0030574 collagen catabolic process(GO:0030574)
0.1 1.8 GO:0071385 cellular response to corticosteroid stimulus(GO:0071384) cellular response to glucocorticoid stimulus(GO:0071385)
0.1 2.3 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.1 11.1 GO:0048706 embryonic skeletal system development(GO:0048706)
0.1 3.9 GO:0042058 regulation of epidermal growth factor receptor signaling pathway(GO:0042058)
0.1 1.3 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.1 3.6 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.1 0.7 GO:0060283 negative regulation of oocyte development(GO:0060283) negative regulation of oocyte maturation(GO:1900194)
0.1 1.8 GO:0051384 response to corticosteroid(GO:0031960) response to glucocorticoid(GO:0051384)
0.1 3.1 GO:0030071 regulation of mitotic metaphase/anaphase transition(GO:0030071)
0.0 0.3 GO:0060605 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.0 0.1 GO:0043060 meiotic metaphase I plate congression(GO:0043060) meiotic metaphase plate congression(GO:0051311)
0.0 0.4 GO:1900454 positive regulation of long term synaptic depression(GO:1900454)
0.0 3.1 GO:0042107 cytokine metabolic process(GO:0042107)
0.0 2.8 GO:0000045 autophagosome assembly(GO:0000045)
0.0 0.2 GO:2000987 positive regulation of fear response(GO:1903367) positive regulation of behavioral fear response(GO:2000987)
0.0 1.4 GO:0031110 regulation of microtubule polymerization or depolymerization(GO:0031110)
0.0 4.7 GO:0006457 protein folding(GO:0006457)
0.0 1.5 GO:0032088 negative regulation of NF-kappaB transcription factor activity(GO:0032088)
0.0 3.1 GO:0007160 cell-matrix adhesion(GO:0007160)
0.0 2.0 GO:0070507 regulation of microtubule cytoskeleton organization(GO:0070507)
0.0 3.3 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 1.4 GO:0030833 regulation of actin filament polymerization(GO:0030833)
0.0 1.2 GO:0045638 negative regulation of myeloid cell differentiation(GO:0045638)
0.0 1.7 GO:0043488 regulation of mRNA stability(GO:0043488)
0.0 1.9 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 2.8 GO:0006814 sodium ion transport(GO:0006814)
0.0 0.1 GO:0018344 protein geranylgeranylation(GO:0018344)
0.0 1.2 GO:0006637 acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.0 0.4 GO:0000027 ribosomal large subunit assembly(GO:0000027)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
17.2 51.6 GO:0016014 dystrobrevin complex(GO:0016014)
8.0 40.1 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
5.2 141.7 GO:0005859 muscle myosin complex(GO:0005859) myosin filament(GO:0032982)
3.9 11.7 GO:1990667 PCSK9-AnxA2 complex(GO:1990667)
3.6 60.5 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
2.9 20.1 GO:1990584 cardiac Troponin complex(GO:1990584)
2.8 25.4 GO:0016460 myosin II complex(GO:0016460)
2.8 8.3 GO:0002095 caveolar macromolecular signaling complex(GO:0002095)
2.4 7.3 GO:0005607 laminin-2 complex(GO:0005607)
2.3 34.9 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
2.3 6.8 GO:0005900 oncostatin-M receptor complex(GO:0005900)
2.1 35.8 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
2.0 8.0 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
1.6 6.4 GO:0071149 TEAD-1-YAP complex(GO:0071148) TEAD-2-YAP complex(GO:0071149)
1.5 4.6 GO:0034665 integrin alpha1-beta1 complex(GO:0034665) integrin alpha7-beta1 complex(GO:0034677) integrin alpha10-beta1 complex(GO:0034680) integrin alpha11-beta1 complex(GO:0034681)
1.5 6.1 GO:0070722 Tle3-Aes complex(GO:0070722)
1.4 8.6 GO:0031523 Myb complex(GO:0031523)
1.3 13.4 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
1.3 9.1 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
1.2 34.5 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
1.1 16.0 GO:0043219 lateral loop(GO:0043219)
1.0 13.5 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
1.0 5.2 GO:0098890 extrinsic component of postsynaptic membrane(GO:0098890)
0.7 91.3 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.7 7.0 GO:0031143 pseudopodium(GO:0031143)
0.6 6.3 GO:0030478 actin cap(GO:0030478)
0.6 96.1 GO:0005901 caveola(GO:0005901)
0.6 12.3 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.5 4.7 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.5 7.2 GO:0030126 COPI vesicle coat(GO:0030126)
0.5 12.3 GO:0005614 interstitial matrix(GO:0005614)
0.5 3.1 GO:0005593 FACIT collagen trimer(GO:0005593)
0.5 10.0 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.5 2.4 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.5 8.1 GO:0046581 intercellular canaliculus(GO:0046581)
0.5 7.2 GO:0099634 postsynaptic specialization membrane(GO:0099634)
0.4 12.4 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.4 52.3 GO:0031674 I band(GO:0031674)
0.4 17.2 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.4 6.1 GO:0044754 autolysosome(GO:0044754)
0.4 3.6 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.4 78.5 GO:0042383 sarcolemma(GO:0042383)
0.4 20.1 GO:0009925 basal plasma membrane(GO:0009925)
0.4 2.5 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.3 7.2 GO:0031528 microvillus membrane(GO:0031528)
0.3 5.6 GO:0045180 basal cortex(GO:0045180)
0.3 42.7 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.3 15.6 GO:0001533 cornified envelope(GO:0001533)
0.3 12.3 GO:0045095 keratin filament(GO:0045095)
0.3 4.0 GO:0000138 Golgi trans cisterna(GO:0000138)
0.3 16.0 GO:0016459 myosin complex(GO:0016459)
0.3 7.3 GO:0030057 desmosome(GO:0030057)
0.2 16.6 GO:0034707 chloride channel complex(GO:0034707)
0.2 7.4 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.2 5.4 GO:0071564 npBAF complex(GO:0071564)
0.2 1.8 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.2 1.9 GO:0000137 Golgi cis cisterna(GO:0000137)
0.2 2.5 GO:0031209 SCAR complex(GO:0031209)
0.2 5.9 GO:0042588 zymogen granule(GO:0042588)
0.2 19.0 GO:0005604 basement membrane(GO:0005604)
0.2 10.1 GO:0031985 Golgi cisterna(GO:0031985)
0.2 0.6 GO:1990716 axonemal central apparatus(GO:1990716)
0.2 18.6 GO:0005913 cell-cell adherens junction(GO:0005913)
0.2 4.9 GO:0031526 brush border membrane(GO:0031526)
0.1 4.3 GO:0008305 integrin complex(GO:0008305)
0.1 6.3 GO:0005902 microvillus(GO:0005902)
0.1 1.6 GO:0043220 Schmidt-Lanterman incisure(GO:0043220)
0.1 26.0 GO:0005875 microtubule associated complex(GO:0005875)
0.1 30.5 GO:0016323 basolateral plasma membrane(GO:0016323)
0.1 46.5 GO:0045177 apical part of cell(GO:0045177)
0.1 1.4 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.1 20.6 GO:0032993 protein-DNA complex(GO:0032993)
0.1 2.1 GO:0018995 host(GO:0018995) host cell part(GO:0033643) host cell(GO:0043657)
0.1 10.2 GO:0043292 contractile fiber(GO:0043292)
0.1 1.1 GO:0034709 methylosome(GO:0034709)
0.1 0.2 GO:0032280 symmetric synapse(GO:0032280)
0.1 6.3 GO:0001750 photoreceptor outer segment(GO:0001750)
0.1 9.4 GO:0016605 PML body(GO:0016605)
0.1 1.7 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 22.3 GO:0043235 receptor complex(GO:0043235)
0.1 3.3 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.1 15.2 GO:0045121 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.1 11.6 GO:0005802 trans-Golgi network(GO:0005802)
0.1 1.0 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 26.0 GO:0005667 transcription factor complex(GO:0005667)
0.0 5.4 GO:0030496 midbody(GO:0030496)
0.0 2.8 GO:0030027 lamellipodium(GO:0030027)
0.0 1.5 GO:0016592 mediator complex(GO:0016592)
0.0 0.7 GO:0070161 anchoring junction(GO:0070161)
0.0 3.3 GO:0072686 mitotic spindle(GO:0072686)
0.0 0.7 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 2.5 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 1.2 GO:0016235 aggresome(GO:0016235)
0.0 0.1 GO:0005715 chiasma(GO:0005712) late recombination nodule(GO:0005715)
0.0 6.3 GO:0005938 cell cortex(GO:0005938)
0.0 5.1 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 0.4 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.9 GO:0030175 filopodium(GO:0030175)
0.0 0.1 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 4.0 GO:0015629 actin cytoskeleton(GO:0015629)
0.0 6.8 GO:0005925 focal adhesion(GO:0005925)
0.0 24.9 GO:0005615 extracellular space(GO:0005615)
0.0 2.5 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 0.4 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.8 GO:0005811 lipid particle(GO:0005811)
0.0 1.8 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 0.5 GO:0045171 intercellular bridge(GO:0045171)
0.0 2.9 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 1.0 GO:0005770 late endosome(GO:0005770)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
10.3 61.7 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
9.0 35.8 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
8.1 56.8 GO:0030899 calcium-dependent ATPase activity(GO:0030899)
5.7 17.2 GO:0004134 glycogen debranching enzyme activity(GO:0004133) 4-alpha-glucanotransferase activity(GO:0004134) amylo-alpha-1,6-glucosidase activity(GO:0004135)
5.3 16.0 GO:0001042 RNA polymerase I core binding(GO:0001042)
4.3 25.9 GO:0031013 troponin I binding(GO:0031013)
4.3 29.9 GO:0042030 ATPase inhibitor activity(GO:0042030)
4.3 72.5 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
4.2 21.1 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
3.6 25.5 GO:0042134 rRNA primary transcript binding(GO:0042134)
3.3 23.4 GO:0070573 metallodipeptidase activity(GO:0070573)
2.4 7.2 GO:0004082 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
2.4 45.0 GO:0038191 neuropilin binding(GO:0038191)
2.3 6.8 GO:0019981 interleukin-6 receptor activity(GO:0004915) interleukin-6 binding(GO:0019981)
2.1 40.1 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
1.8 9.1 GO:0048763 calcium-induced calcium release activity(GO:0048763)
1.7 15.5 GO:0004687 myosin light chain kinase activity(GO:0004687)
1.6 6.4 GO:0015057 thrombin receptor activity(GO:0015057)
1.5 12.1 GO:0043237 laminin-1 binding(GO:0043237)
1.5 13.6 GO:0030368 interleukin-17 receptor activity(GO:0030368)
1.4 7.2 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
1.4 8.6 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
1.4 13.9 GO:0031995 insulin-like growth factor II binding(GO:0031995)
1.4 9.6 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
1.3 9.2 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
1.3 11.7 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
1.2 8.3 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
1.2 9.4 GO:0031432 titin binding(GO:0031432)
1.2 55.5 GO:0008307 structural constituent of muscle(GO:0008307)
1.2 8.1 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
1.1 9.1 GO:0001849 complement component C1q binding(GO:0001849)
1.1 6.8 GO:0015232 heme transporter activity(GO:0015232)
1.1 52.6 GO:0030552 cAMP binding(GO:0030552)
1.0 5.1 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
1.0 10.7 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
1.0 21.2 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.9 4.7 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.9 14.9 GO:0045294 alpha-catenin binding(GO:0045294)
0.9 10.9 GO:0008381 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.8 10.4 GO:0070700 BMP receptor binding(GO:0070700)
0.8 13.5 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.8 5.5 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.8 18.4 GO:0017049 GTP-Rho binding(GO:0017049)
0.8 4.6 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.7 6.2 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.7 9.6 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.7 7.4 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.7 4.0 GO:0047493 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.7 3.9 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.6 1.9 GO:0042936 dipeptide transporter activity(GO:0042936)
0.6 8.1 GO:0071253 connexin binding(GO:0071253)
0.6 6.7 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.6 6.5 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.6 1.7 GO:0038052 type 1 metabotropic glutamate receptor binding(GO:0031798) RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.5 5.1 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.5 6.1 GO:0102336 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.5 13.5 GO:0043274 phospholipase binding(GO:0043274)
0.5 5.3 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.5 2.4 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.5 5.2 GO:0032051 clathrin light chain binding(GO:0032051)
0.5 15.9 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.5 7.2 GO:0043495 protein anchor(GO:0043495)
0.4 10.3 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.4 36.1 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.4 3.6 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.4 3.9 GO:0042285 xylosyltransferase activity(GO:0042285)
0.4 13.2 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.4 8.4 GO:0017160 Ral GTPase binding(GO:0017160)
0.4 11.6 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.4 4.6 GO:0017154 semaphorin receptor activity(GO:0017154)
0.4 4.9 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.4 1.2 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.4 2.8 GO:0001515 opioid peptide activity(GO:0001515)
0.4 2.8 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.4 12.3 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.4 2.2 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.4 7.4 GO:0035497 cAMP response element binding(GO:0035497)
0.4 6.5 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.4 27.1 GO:0017080 sodium channel regulator activity(GO:0017080)
0.4 9.6 GO:0030506 ankyrin binding(GO:0030506)
0.3 60.3 GO:0030165 PDZ domain binding(GO:0030165)
0.3 3.4 GO:0005113 patched binding(GO:0005113)
0.3 5.0 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.3 1.3 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.3 1.0 GO:0047057 oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
0.3 3.2 GO:0008420 CTD phosphatase activity(GO:0008420)
0.3 3.7 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.3 6.3 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.3 22.2 GO:0035254 glutamate receptor binding(GO:0035254)
0.3 4.6 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.3 14.4 GO:0050681 androgen receptor binding(GO:0050681)
0.3 0.8 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.2 1.2 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.2 1.7 GO:0047276 N-acetyllactosaminide 3-alpha-galactosyltransferase activity(GO:0047276)
0.2 1.0 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.2 1.7 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.2 3.0 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.2 3.6 GO:0050308 sugar-phosphatase activity(GO:0050308)
0.2 1.1 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.2 18.9 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.2 1.9 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.2 1.3 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.2 11.1 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.2 19.1 GO:0005080 protein kinase C binding(GO:0005080)
0.2 2.1 GO:0070878 primary miRNA binding(GO:0070878)
0.2 2.5 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.2 10.3 GO:0033613 activating transcription factor binding(GO:0033613)
0.2 3.0 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.2 7.3 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.2 33.9 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.2 4.8 GO:0030371 translation repressor activity(GO:0030371)
0.2 0.9 GO:0042328 heparan sulfate N-acetylglucosaminyltransferase activity(GO:0042328)
0.2 0.9 GO:0070728 leucine binding(GO:0070728)
0.1 1.6 GO:0032794 GTPase activating protein binding(GO:0032794)
0.1 1.6 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.1 16.6 GO:0005254 chloride channel activity(GO:0005254)
0.1 1.3 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 2.8 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.1 1.0 GO:0034711 inhibin binding(GO:0034711)
0.1 13.6 GO:0001191 transcriptional repressor activity, RNA polymerase II transcription factor binding(GO:0001191)
0.1 1.8 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.1 4.1 GO:0004190 aspartic-type endopeptidase activity(GO:0004190)
0.1 15.0 GO:0003774 motor activity(GO:0003774)
0.1 3.1 GO:0015464 acetylcholine receptor activity(GO:0015464)
0.1 3.3 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 5.0 GO:0042974 retinoic acid receptor binding(GO:0042974)
0.1 5.0 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.1 1.9 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.1 1.5 GO:0030957 Tat protein binding(GO:0030957)
0.1 4.3 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.1 6.0 GO:0019894 kinesin binding(GO:0019894)
0.1 2.5 GO:0005355 glucose transmembrane transporter activity(GO:0005355)
0.1 1.6 GO:0004697 protein kinase C activity(GO:0004697)
0.1 62.7 GO:0003779 actin binding(GO:0003779)
0.1 1.7 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.1 1.9 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.1 9.8 GO:0019838 growth factor binding(GO:0019838)
0.1 15.9 GO:0003714 transcription corepressor activity(GO:0003714)
0.1 1.5 GO:0070491 repressing transcription factor binding(GO:0070491)
0.1 0.4 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.1 4.9 GO:0043621 protein self-association(GO:0043621)
0.1 2.0 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.1 5.4 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.1 0.8 GO:0070739 protein-glutamic acid ligase activity(GO:0070739)
0.1 1.0 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 1.5 GO:0031489 myosin V binding(GO:0031489)
0.1 1.3 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.1 2.0 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.1 2.3 GO:0030332 cyclin binding(GO:0030332)
0.0 0.7 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 3.3 GO:0032947 protein complex scaffold(GO:0032947)
0.0 32.8 GO:0005509 calcium ion binding(GO:0005509)
0.0 5.2 GO:0005178 integrin binding(GO:0005178)
0.0 0.5 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.0 1.5 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)
0.0 0.8 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 2.9 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.0 4.8 GO:0051082 unfolded protein binding(GO:0051082)
0.0 0.8 GO:0016303 1-phosphatidylinositol-3-kinase activity(GO:0016303)
0.0 1.7 GO:0030507 spectrin binding(GO:0030507)
0.0 0.9 GO:0005123 death receptor binding(GO:0005123)
0.0 25.2 GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977)
0.0 7.6 GO:0045296 cadherin binding(GO:0045296)
0.0 4.6 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.1 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.0 0.6 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 18.6 GO:0008270 zinc ion binding(GO:0008270)
0.0 8.2 GO:0003924 GTPase activity(GO:0003924)
0.0 3.6 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.1 GO:0032137 guanine/thymine mispair binding(GO:0032137)
0.0 0.9 GO:0035257 nuclear hormone receptor binding(GO:0035257)
0.0 7.7 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 0.5 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 0.5 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.7 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.3 GO:0050699 WW domain binding(GO:0050699)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 61.6 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.6 29.9 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.5 38.6 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.5 45.7 PID TGFBR PATHWAY TGF-beta receptor signaling
0.4 32.8 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.4 76.9 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.3 19.4 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.3 67.1 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.3 7.7 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.3 16.6 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.3 9.8 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.3 2.9 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.3 21.1 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.2 10.0 PID RAS PATHWAY Regulation of Ras family activation
0.2 9.6 PID INSULIN PATHWAY Insulin Pathway
0.2 6.0 PID IL27 PATHWAY IL27-mediated signaling events
0.2 2.8 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.2 3.2 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.2 5.1 PID ENDOTHELIN PATHWAY Endothelins
0.1 1.9 ST GA12 PATHWAY G alpha 12 Pathway
0.1 6.3 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.1 6.0 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.1 35.3 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 4.0 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.1 1.7 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.1 3.8 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.1 7.0 PID ILK PATHWAY Integrin-linked kinase signaling
0.1 2.3 PID ARF 3PATHWAY Arf1 pathway
0.1 2.4 PID EPHA FWDPATHWAY EPHA forward signaling
0.1 9.7 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.1 1.6 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.1 5.3 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.1 2.5 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.1 7.1 PID RHOA REG PATHWAY Regulation of RhoA activity
0.1 8.1 PID AR PATHWAY Coregulation of Androgen receptor activity
0.1 1.4 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.1 1.2 PID NETRIN PATHWAY Netrin-mediated signaling events
0.1 3.2 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 3.6 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 2.2 PID FGF PATHWAY FGF signaling pathway
0.0 2.1 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 1.9 PID PLK1 PATHWAY PLK1 signaling events
0.0 2.1 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.0 0.5 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 0.9 PID P53 REGULATION PATHWAY p53 pathway
0.0 0.6 PID AURORA B PATHWAY Aurora B signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 143.2 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
2.2 43.7 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
2.1 60.4 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
1.6 55.6 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
1.2 45.3 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
1.0 13.1 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.9 26.4 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.8 17.2 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.8 25.3 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.8 25.7 REACTOME GRB2 EVENTS IN ERBB2 SIGNALING Genes involved in GRB2 events in ERBB2 signaling
0.8 22.9 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.7 15.7 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.5 18.8 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.5 5.1 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.4 7.5 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.4 6.4 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.4 0.8 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.4 8.0 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.4 7.1 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.4 6.0 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.3 6.2 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.3 14.9 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.3 18.9 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.2 5.8 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.2 4.6 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.2 18.6 REACTOME ANTIGEN PROCESSING CROSS PRESENTATION Genes involved in Antigen processing-Cross presentation
0.2 2.2 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.2 6.1 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.2 4.3 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.1 2.5 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.1 4.6 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1 1.6 REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES Genes involved in p75NTR recruits signalling complexes
0.1 4.3 REACTOME SIGNAL TRANSDUCTION BY L1 Genes involved in Signal transduction by L1
0.1 2.2 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.1 1.7 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.1 12.2 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.1 1.8 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.1 4.0 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.1 19.0 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.1 2.0 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.1 2.2 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 1.3 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1 0.5 REACTOME FGFR1 LIGAND BINDING AND ACTIVATION Genes involved in FGFR1 ligand binding and activation
0.1 1.0 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.1 1.2 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.1 3.7 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.1 3.1 REACTOME MYOGENESIS Genes involved in Myogenesis
0.1 4.9 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.0 12.5 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 1.6 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 0.8 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 1.7 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.0 2.0 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.6 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.0 2.5 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 1.1 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.0 0.6 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.7 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 1.3 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 1.0 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors