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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Tfap2a

Z-value: 1.05

Motif logo

Transcription factors associated with Tfap2a

Gene Symbol Gene ID Gene Info
ENSMUSG00000021359.17 Tfap2a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Tfap2amm39_v1_chr13_-_40883893_408839190.325.7e-03Click!

Activity profile of Tfap2a motif

Sorted Z-values of Tfap2a motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Tfap2a

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr12_-_76869282 7.24 ENSMUST00000021459.14
RAB15, member RAS oncogene family
chr11_-_103844870 5.68 ENSMUST00000103075.11
N-ethylmaleimide sensitive fusion protein
chr15_-_44978223 5.56 ENSMUST00000022967.7
potassium channel, subfamily V, member 1
chr13_+_43276323 5.21 ENSMUST00000136576.8
phosphatase and actin regulator 1
chr2_+_103254401 4.88 ENSMUST00000028609.14
E74-like factor 5
chr2_+_103254465 4.78 ENSMUST00000171693.8
E74-like factor 5
chr5_-_44139099 4.37 ENSMUST00000061299.9
fibroblast growth factor binding protein 1
chrX_+_10351360 4.37 ENSMUST00000076354.13
ENSMUST00000115526.2
tetraspanin 7
chr5_-_44139121 4.31 ENSMUST00000199894.2
fibroblast growth factor binding protein 1
chr2_+_119572770 4.30 ENSMUST00000028758.8
inositol 1,4,5-trisphosphate 3-kinase A
chr9_+_59614877 4.23 ENSMUST00000128944.8
ENSMUST00000098661.10
GRAM domain containing 2
chr11_-_102787950 4.08 ENSMUST00000067444.10
glial fibrillary acidic protein
chr11_+_78213791 3.95 ENSMUST00000017534.15
aldolase C, fructose-bisphosphate
chr2_+_25179903 3.95 ENSMUST00000028337.7
leucine rich repeat containing 26
chr13_-_110416637 3.93 ENSMUST00000167824.3
ENSMUST00000224180.2
RAB3C, member RAS oncogene family
chr11_-_102787972 3.49 ENSMUST00000077902.5
glial fibrillary acidic protein
chr16_-_18445172 3.48 ENSMUST00000231335.2
ENSMUST00000232653.2
predicted gene, 49601
septin 5
chr9_+_109760856 3.43 ENSMUST00000169851.8
microtubule-associated protein 4
chr7_+_97492124 3.40 ENSMUST00000033040.12
p21 (RAC1) activated kinase 1
chr10_+_99851679 3.29 ENSMUST00000130190.8
ENSMUST00000218200.2
ENSMUST00000020129.8
kit ligand
chr9_-_66951234 3.25 ENSMUST00000113690.8
tropomyosin 1, alpha
chr7_-_30776081 3.19 ENSMUST00000072331.13
ENSMUST00000167369.8
FXYD domain-containing ion transport regulator 3
chr14_-_65499835 3.15 ENSMUST00000131309.3
frizzled class receptor 3
chr2_+_102380357 3.12 ENSMUST00000028612.8
peptidase domain containing associated with muscle regeneration 1
chr2_+_83642910 3.09 ENSMUST00000051454.4
family with sequence similarity 171, member B
chr13_+_25029088 3.04 ENSMUST00000006893.9
RIKEN cDNA D130043K22 gene
chr10_-_76181089 3.01 ENSMUST00000036033.14
ENSMUST00000160048.8
ENSMUST00000105417.10
disco interacting protein 2 homolog A
chrX_-_8072714 3.01 ENSMUST00000089403.10
ENSMUST00000077595.12
ENSMUST00000089402.10
ENSMUST00000082320.12
porcupine O-acyltransferase
chr5_+_107585774 3.00 ENSMUST00000162298.4
ENSMUST00000094541.4
ENSMUST00000211896.2
BTB (POZ) domain containing 8
chr17_+_70276210 2.99 ENSMUST00000060072.12
DLG associated protein 1
chr7_+_30487322 2.98 ENSMUST00000189673.7
ENSMUST00000190990.7
ENSMUST00000189962.7
ENSMUST00000187493.7
ENSMUST00000098559.3
keratinocyte differentiation associated protein
chr1_+_191873078 2.95 ENSMUST00000078470.12
ENSMUST00000110844.3
potassium voltage-gated channel, subfamily H (eag-related), member 1
chr8_+_126721878 2.91 ENSMUST00000046765.10
potassium channel, subfamily K, member 1
chr1_-_75254989 2.91 ENSMUST00000039534.11
regulated endocrine-specific protein 18
chr4_-_155095441 2.89 ENSMUST00000105631.9
ENSMUST00000139976.9
ENSMUST00000145662.9
phospholipase C, eta 2
chr8_+_126722113 2.87 ENSMUST00000212831.2
potassium channel, subfamily K, member 1
chr6_-_60805873 2.78 ENSMUST00000114268.5
synuclein, alpha
chr14_+_68321302 2.75 ENSMUST00000022639.8
neurofilament, light polypeptide
chr15_-_74599860 2.73 ENSMUST00000023261.4
ENSMUST00000190433.2
secreted Ly6/Plaur domain containing 1
chr17_+_70276068 2.72 ENSMUST00000133983.8
DLG associated protein 1
chr5_-_52723700 2.71 ENSMUST00000039750.7
leucine-rich repeat LGI family, member 2
chrX_-_102230225 2.71 ENSMUST00000121720.2
nucleosome assembly protein 1-like 2
chr6_+_36364990 2.70 ENSMUST00000172278.8
cholinergic receptor, muscarinic 2, cardiac
chr11_-_118800314 2.67 ENSMUST00000117731.8
ENSMUST00000106278.9
ENSMUST00000120061.8
ENSMUST00000017576.11
RNA binding protein, fox-1 homolog (C. elegans) 3
chr15_-_37792237 2.65 ENSMUST00000168992.8
ENSMUST00000148652.9
neurocalcin delta
chr7_-_3680530 2.64 ENSMUST00000038743.15
transmembrane channel-like gene family 4
chr18_+_61058684 2.64 ENSMUST00000102888.10
ENSMUST00000025519.11
calcium/calmodulin-dependent protein kinase II alpha
chr7_+_43430459 2.63 ENSMUST00000014058.11
kallikrein related-peptidase 10
chr4_-_127224591 2.59 ENSMUST00000046532.4
gap junction protein, beta 3
chrX_+_135723531 2.59 ENSMUST00000113085.2
proteolipid protein (myelin) 1
chr11_+_63022328 2.56 ENSMUST00000018361.10
peripheral myelin protein 22
chr3_-_84387700 2.56 ENSMUST00000194027.2
ENSMUST00000107689.7
FH2 domain containing 1
chr9_-_31043076 2.53 ENSMUST00000034478.3
suppression of tumorigenicity 14 (colon carcinoma)
chr1_-_38875757 2.53 ENSMUST00000147695.9
LON peptidase N-terminal domain and ring finger 2
chr17_+_70276382 2.49 ENSMUST00000146730.9
DLG associated protein 1
chr17_-_16050913 2.49 ENSMUST00000231281.2
repulsive guidance molecule family member B
chr11_-_86964881 2.47 ENSMUST00000020804.8
glycerophosphodiester phosphodiesterase domain containing 1
chr9_-_66951114 2.45 ENSMUST00000113686.8
tropomyosin 1, alpha
chr3_-_88280047 2.45 ENSMUST00000107543.8
ENSMUST00000107542.2
bone gamma-carboxyglutamate protein 3
chrX_+_72108393 2.41 ENSMUST00000060418.8
paraneoplastic antigen MA3
chr11_-_70924288 2.39 ENSMUST00000238695.2
RIKEN cDNA 6330403K07 gene
chr2_+_154032731 2.35 ENSMUST00000081816.11
BPI fold containing family B, member 1
chrX_+_135723420 2.34 ENSMUST00000033800.13
proteolipid protein (myelin) 1
chr7_+_24335969 2.34 ENSMUST00000080718.6
Ly6/Plaur domain containing 3
chr11_-_100026754 2.33 ENSMUST00000107411.3
keratin 15
chr4_-_155103837 2.30 ENSMUST00000126098.2
ENSMUST00000176194.8
phospholipase C, eta 2
chr9_+_26645024 2.29 ENSMUST00000160899.8
ENSMUST00000161431.3
ENSMUST00000159799.8
beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P)
chr3_-_94693740 2.23 ENSMUST00000153263.9
ENSMUST00000107272.7
ENSMUST00000155485.4
cingulin
chr17_-_37178079 2.22 ENSMUST00000025329.13
ENSMUST00000174195.8
tripartite motif-containing 15
chr10_+_75009797 2.22 ENSMUST00000218465.2
BCR activator of RhoGEF and GTPase
chrX_-_149440388 2.22 ENSMUST00000151403.9
ENSMUST00000087253.11
ENSMUST00000112709.8
ENSMUST00000163969.8
ENSMUST00000087258.10
trophinin
chr19_-_10217968 2.20 ENSMUST00000189897.2
ENSMUST00000186056.7
ENSMUST00000088013.12
myelin regulatory factor
chr7_-_121785385 2.19 ENSMUST00000033153.9
endoplasmic reticulum (ER) to nucleus signalling 2
chrX_-_97934387 2.18 ENSMUST00000113826.8
ENSMUST00000033560.9
ENSMUST00000142267.2
oligophrenin 1
chr9_-_66951025 2.18 ENSMUST00000113695.8
tropomyosin 1, alpha
chr11_+_100900278 2.17 ENSMUST00000103110.10
ENSMUST00000044721.13
ENSMUST00000168757.9
ATPase, H+ transporting, lysosomal V0 subunit A1
chr1_+_132808011 2.17 ENSMUST00000027706.4
leucine rich repeat protein 2, neuronal
chrX_-_74621828 2.14 ENSMUST00000033545.6
RAB39B, member RAS oncogene family
chr2_+_103255165 2.13 ENSMUST00000126290.2
E74-like factor 5
chr17_+_35295909 2.13 ENSMUST00000013910.5
lymphocyte antigen 6 complex, locus G6E
chr9_-_66951151 2.09 ENSMUST00000113696.8
tropomyosin 1, alpha
chr4_-_129015027 2.09 ENSMUST00000030572.10
hippocalcin
chr17_-_57289121 2.09 ENSMUST00000056113.5
alkaline ceramidase 1
chr4_-_148372384 2.08 ENSMUST00000047720.9
dispatched RND transporter family member 3
chr4_-_57143437 2.07 ENSMUST00000095076.10
ENSMUST00000030142.4
erythrocyte membrane protein band 4.1 like 4b
chr14_-_55163452 2.06 ENSMUST00000227037.2
embryonal Fyn-associated substrate
chr19_-_5507532 2.05 ENSMUST00000236881.2
coiled-coil domain containing 85B
chr14_-_61275340 2.03 ENSMUST00000225730.2
ENSMUST00000111236.4
tumor necrosis factor receptor superfamily, member 19
chr7_-_43139390 2.03 ENSMUST00000107974.3
IgLON family member 5
chr12_-_45120895 2.03 ENSMUST00000120531.8
ENSMUST00000143376.8
syntaxin binding protein 6 (amisyn)
chr5_-_123270449 2.02 ENSMUST00000186469.7
ras homolog family member F (in filopodia)
chr1_+_34840785 2.00 ENSMUST00000047664.16
ENSMUST00000211073.2
Rho guanine nucleotide exchange factor (GEF) 4
novel protein
chr15_+_74435217 2.00 ENSMUST00000190524.7
adhesion G protein-coupled receptor B1
chr7_+_113365235 1.99 ENSMUST00000046687.16
spondin 1, (f-spondin) extracellular matrix protein
chr7_+_49624978 1.98 ENSMUST00000107603.2
NEL-like 1
chr7_-_97827461 1.98 ENSMUST00000040971.14
calpain 5
chr16_-_22475915 1.97 ENSMUST00000089925.10
diacylglycerol kinase, gamma
chr2_+_119067929 1.96 ENSMUST00000110816.8
serine protease inhibitor, Kunitz type 1
chr2_+_119067832 1.96 ENSMUST00000028783.14
serine protease inhibitor, Kunitz type 1
chr15_+_80862074 1.95 ENSMUST00000229727.2
small G protein signaling modulator 3
chr11_+_69920849 1.94 ENSMUST00000143920.4
discs large MAGUK scaffold protein 4
chrX_+_21581135 1.94 ENSMUST00000033414.8
solute carrier family 6 (neurotransmitter transporter), member 14
chr13_-_99653045 1.92 ENSMUST00000064762.6
microtubule-associated protein 1B
chr11_+_69920956 1.91 ENSMUST00000232115.2
discs large MAGUK scaffold protein 4
chr4_+_133788065 1.88 ENSMUST00000227683.2
crystallin beta-gamma domain containing 2
chr18_-_38342815 1.88 ENSMUST00000057185.13
protocadherin 1
chr4_-_11966367 1.87 ENSMUST00000056050.5
ENSMUST00000108299.2
ENSMUST00000108297.3
pyruvate dehyrogenase phosphatase catalytic subunit 1
chr17_+_35295894 1.87 ENSMUST00000172678.8
lymphocyte antigen 6 complex, locus G6E
chr5_+_57875309 1.86 ENSMUST00000191837.6
ENSMUST00000068110.10
protocadherin 7
chr18_+_61058716 1.86 ENSMUST00000115297.8
calcium/calmodulin-dependent protein kinase II alpha
chr11_+_76070483 1.85 ENSMUST00000129853.8
TLC domain containing 3A
chr4_-_127247864 1.83 ENSMUST00000106090.8
ENSMUST00000060419.2
gap junction protein, beta 4
chr8_-_47866869 1.83 ENSMUST00000211882.2
storkhead box 2
chr6_-_113696390 1.81 ENSMUST00000203588.2
ENSMUST00000204163.3
ENSMUST00000203363.3
ghrelin
chr4_+_138181616 1.80 ENSMUST00000050918.4
calcium/calmodulin-dependent protein kinase II inhibitor 1
chr18_+_77273510 1.80 ENSMUST00000075290.8
ENSMUST00000079618.11
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5
chr7_+_127347339 1.77 ENSMUST00000206893.2
F-box and leucine-rich repeat protein 19
chr2_+_28423367 1.77 ENSMUST00000113893.8
ENSMUST00000100241.10
ral guanine nucleotide dissociation stimulator
chr9_-_66950991 1.76 ENSMUST00000113689.8
ENSMUST00000113684.8
tropomyosin 1, alpha
chr4_+_43381979 1.74 ENSMUST00000035645.12
ENSMUST00000144911.8
RUN and SH3 domain containing 2
chr10_+_79552421 1.74 ENSMUST00000099513.8
ENSMUST00000020581.3
hyperpolarization-activated, cyclic nucleotide-gated K+ 2
chr14_-_24054927 1.70 ENSMUST00000145596.3
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr5_+_117979899 1.69 ENSMUST00000142742.9
nitric oxide synthase 1, neuronal
chr2_+_165345707 1.69 ENSMUST00000029196.5
solute carrier family 2 (facilitated glucose transporter), member 10
chr5_-_146521629 1.68 ENSMUST00000200112.2
ENSMUST00000197431.2
ENSMUST00000197825.2
G-protein coupled receptor 12
chr13_-_95661726 1.66 ENSMUST00000022185.10
coagulation factor II (thrombin) receptor-like 1
chr11_-_101877832 1.63 ENSMUST00000107173.9
ENSMUST00000107172.8
dual specificity phosphatase 3 (vaccinia virus phosphatase VH1-related)
chr13_+_58956495 1.62 ENSMUST00000225950.2
ENSMUST00000225583.2
neurotrophic tyrosine kinase, receptor, type 2
chr2_-_173117936 1.62 ENSMUST00000139306.2
prostate transmembrane protein, androgen induced 1
chr1_+_182591425 1.62 ENSMUST00000155229.7
ENSMUST00000153348.8
sushi domain containing 4
chrX_-_135116192 1.60 ENSMUST00000113120.2
ENSMUST00000113118.2
ENSMUST00000058125.9
brain expressed X-linked 1
chr14_-_55163311 1.59 ENSMUST00000022813.8
embryonal Fyn-associated substrate
chr4_+_43383449 1.59 ENSMUST00000135216.2
ENSMUST00000152322.8
RUN and SH3 domain containing 2
chr7_-_103832599 1.58 ENSMUST00000216612.3
olfactory receptor 648
chr14_+_70791127 1.56 ENSMUST00000161069.8
lysine demethylase and nuclear receptor corepressor
chr4_+_11758147 1.56 ENSMUST00000029871.12
ENSMUST00000108303.2
cadherin 17
chr7_+_4928784 1.55 ENSMUST00000057612.9
scavenger receptor cysteine rich family, 5 domains
chr9_-_49710190 1.54 ENSMUST00000114476.8
ENSMUST00000193547.6
neural cell adhesion molecule 1
chr9_+_21095399 1.53 ENSMUST00000115458.9
phosphodiesterase 4A, cAMP specific
chr12_-_87037204 1.53 ENSMUST00000222543.2
zinc finger, DHHC-type containing 22
chr5_-_93192881 1.52 ENSMUST00000061328.6
sosondowah ankyrin repeat domain family member B
chr9_-_44646487 1.52 ENSMUST00000034611.15
pleckstrin homology like domain, family B, member 1
chr1_-_64995891 1.49 ENSMUST00000123225.2
pleckstrin homology domain containing, family M, member 3
chr6_-_137626207 1.49 ENSMUST00000134630.6
ENSMUST00000058210.13
ENSMUST00000111878.8
epidermal growth factor receptor pathway substrate 8
chr10_-_83484467 1.46 ENSMUST00000146876.9
ENSMUST00000176294.2
adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2
chr1_-_132294807 1.46 ENSMUST00000136828.3
transmembrane and coiled-coil domains 2
chr2_+_102488985 1.46 ENSMUST00000080210.10
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chrX_+_92718695 1.45 ENSMUST00000045898.4
phosphate cytidylyltransferase 1, choline, beta isoform
chr12_+_84161095 1.45 ENSMUST00000123491.8
ENSMUST00000046340.9
ENSMUST00000136159.2
dynein, axonemal, light chain 1
chr2_+_70393782 1.45 ENSMUST00000123330.3
glutamate decarboxylase 1
chr10_+_24099415 1.44 ENSMUST00000095784.3
monooxygenase, DBH-like 1
chr3_-_141875070 1.42 ENSMUST00000106230.2
bone morphogenetic protein receptor, type 1B
chr3_-_8732316 1.42 ENSMUST00000042412.5
hairy/enhancer-of-split related with YRPW motif 1
chr4_-_46602192 1.41 ENSMUST00000107756.4
coronin, actin binding protein 2A
chr2_-_150746574 1.41 ENSMUST00000056149.15
abhydrolase domain containing 12
chr11_-_97464866 1.40 ENSMUST00000207653.2
ENSMUST00000107593.8
SRC kinase signaling inhibitor 1
chr2_-_173118315 1.40 ENSMUST00000036248.13
prostate transmembrane protein, androgen induced 1
chrX_-_52645649 1.40 ENSMUST00000088779.5
retrotransposon Gag like 8A
chr1_+_75377616 1.40 ENSMUST00000122266.3
SPEG complex locus
chr7_+_127347308 1.39 ENSMUST00000188580.3
F-box and leucine-rich repeat protein 19
chr16_+_17093941 1.39 ENSMUST00000164950.11
transmembrane protein 191C
chr18_+_62681982 1.39 ENSMUST00000055725.12
ENSMUST00000162365.8
serine peptidase inhibitor, Kazal type 10
chr17_-_16051295 1.39 ENSMUST00000231985.2
repulsive guidance molecule family member B
chr9_-_62444318 1.38 ENSMUST00000048043.12
coronin, actin binding protein, 2B
chr7_+_141342696 1.38 ENSMUST00000155534.9
ENSMUST00000041924.14
ENSMUST00000163321.3
mucin 5, subtypes A and C, tracheobronchial/gastric
chrX_-_149440362 1.38 ENSMUST00000148604.2
trophinin
chr18_+_37818263 1.37 ENSMUST00000194418.2
protocadherin gamma subfamily A, 4
chr2_-_171885386 1.33 ENSMUST00000087950.4
cerebellin 4 precursor protein
chr11_+_69920542 1.32 ENSMUST00000232266.2
ENSMUST00000132597.5
discs large MAGUK scaffold protein 4
chr7_-_109322993 1.32 ENSMUST00000106735.9
ENSMUST00000033334.5
cDNA sequence BC051019
chr8_+_75720286 1.32 ENSMUST00000211863.2
HMG box domain containing 4
chr9_-_75466865 1.32 ENSMUST00000215821.2
tropomodulin 3
chr8_-_59154041 1.31 ENSMUST00000188531.7
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 6
chr4_+_128777339 1.31 ENSMUST00000035667.9
tripartite motif-containing 62
chr9_-_44632680 1.29 ENSMUST00000148929.2
ENSMUST00000123406.8
pleckstrin homology like domain, family B, member 1
chr15_+_80861966 1.28 ENSMUST00000139517.9
ENSMUST00000137255.3
ENSMUST00000137004.2
small G protein signaling modulator 3
chr9_-_58109564 1.28 ENSMUST00000163897.8
ENSMUST00000215950.2
immunoglobulin superfamily containing leucine-rich repeat 2
chr3_-_132655804 1.28 ENSMUST00000117164.8
ENSMUST00000093971.5
ENSMUST00000042729.16
nephronectin
chr5_+_130200639 1.27 ENSMUST00000119797.8
ENSMUST00000148264.8
RAB guanine nucleotide exchange factor (GEF) 1
chrX_+_73372664 1.27 ENSMUST00000004326.4
plexin A3
chr11_-_61470462 1.27 ENSMUST00000147501.8
ENSMUST00000146455.8
ENSMUST00000108711.8
ENSMUST00000108712.8
ENSMUST00000001063.15
ENSMUST00000108713.8
ENSMUST00000179936.8
ENSMUST00000178202.8
epsin 2
chr3_-_132655954 1.26 ENSMUST00000042744.16
ENSMUST00000117811.8
nephronectin
chr11_+_59197746 1.26 ENSMUST00000000128.10
ENSMUST00000108783.4
wingless-type MMTV integration site family, member 9A
chr9_+_26645141 1.26 ENSMUST00000115269.9
beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P)
chr13_+_3887757 1.25 ENSMUST00000042219.6
calmodulin 4
chr2_+_69652714 1.25 ENSMUST00000053087.4
kelch-like 23
chr3_+_131270529 1.25 ENSMUST00000029666.14
3'-phosphoadenosine 5'-phosphosulfate synthase 1
chr17_+_28491085 1.25 ENSMUST00000169040.3
peroxisome proliferator activator receptor delta
chr6_-_120799500 1.24 ENSMUST00000204699.2
ATPase, H+ transporting, lysosomal V1 subunit E1
chr8_-_100143029 1.24 ENSMUST00000155527.8
ENSMUST00000142129.8
ENSMUST00000093249.11
ENSMUST00000142475.3
ENSMUST00000128860.8
cadherin 8
chr13_-_34529157 1.23 ENSMUST00000040336.12
solute carrier family 22, member 23
chr8_+_40876827 1.23 ENSMUST00000049389.11
ENSMUST00000128166.8
ENSMUST00000167766.2
zinc finger, DHHC domain containing 2
chr6_+_145879839 1.23 ENSMUST00000032383.14
sarcospan
chr3_-_94693780 1.23 ENSMUST00000107273.9
ENSMUST00000238849.2
cingulin
chr6_+_17306334 1.21 ENSMUST00000007799.13
ENSMUST00000115456.6
caveolin 1, caveolae protein
chr2_-_168123015 1.21 ENSMUST00000109191.2
potassium voltage-gated channel, subfamily G, member 1
chr9_-_112016966 1.21 ENSMUST00000178410.2
ENSMUST00000172380.10
cyclic AMP-regulated phosphoprotein, 21
chr7_+_126396779 1.20 ENSMUST00000205324.2
TLC domain containing 3B
chr3_+_121517158 1.20 ENSMUST00000029771.13
coagulation factor III
chr8_-_46452896 1.19 ENSMUST00000053558.10
ankyrin repeat domain 37

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.1 3.1 GO:0045976 negative regulation of mitotic cell cycle, embryonic(GO:0045976)
2.0 11.7 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
1.7 11.8 GO:0001712 ectodermal cell fate commitment(GO:0001712)
1.3 10.4 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
0.9 2.7 GO:0033693 neurofilament bundle assembly(GO:0033693)
0.9 8.7 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.8 3.4 GO:0061534 gamma-aminobutyric acid secretion, neurotransmission(GO:0061534)
0.8 2.5 GO:0060671 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.8 5.8 GO:0060075 regulation of resting membrane potential(GO:0060075)
0.7 3.5 GO:1901252 regulation of intracellular transport of viral material(GO:1901252)
0.7 2.1 GO:0030827 negative regulation of cGMP metabolic process(GO:0030824) negative regulation of cGMP biosynthetic process(GO:0030827) negative regulation of guanylate cyclase activity(GO:0031283)
0.7 9.3 GO:0098953 receptor diffusion trapping(GO:0098953) postsynaptic neurotransmitter receptor diffusion trapping(GO:0098970) neurotransmitter receptor diffusion trapping(GO:0099628)
0.7 3.3 GO:0034441 plasma lipoprotein particle oxidation(GO:0034441)
0.6 8.2 GO:0070842 aggresome assembly(GO:0070842)
0.6 3.6 GO:1902035 positive regulation of hematopoietic stem cell proliferation(GO:1902035)
0.6 4.1 GO:0051012 microtubule sliding(GO:0051012)
0.6 1.7 GO:0070949 positive regulation of eosinophil degranulation(GO:0043311) regulation of neutrophil mediated cytotoxicity(GO:0070948) regulation of neutrophil mediated killing of symbiont cell(GO:0070949) positive regulation of renin secretion into blood stream(GO:1900135) positive regulation of eosinophil activation(GO:1902568)
0.5 2.7 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.5 1.6 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.5 2.5 GO:0097195 pilomotor reflex(GO:0097195) positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000721)
0.5 3.0 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.5 3.0 GO:1900085 negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609)
0.5 2.9 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.5 1.4 GO:2000820 negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000820)
0.5 1.4 GO:0046462 monoacylglycerol metabolic process(GO:0046462)
0.5 1.8 GO:2000506 regulation of gastric mucosal blood circulation(GO:1904344) positive regulation of gastric mucosal blood circulation(GO:1904346) gastric mucosal blood circulation(GO:1990768) negative regulation of energy homeostasis(GO:2000506)
0.4 1.7 GO:1901204 regulation of adrenergic receptor signaling pathway involved in heart process(GO:1901204)
0.4 2.1 GO:0051684 maintenance of Golgi location(GO:0051684)
0.4 2.1 GO:0010446 response to alkaline pH(GO:0010446)
0.4 3.2 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.4 1.6 GO:0030450 regulation of complement activation, classical pathway(GO:0030450)
0.4 1.2 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.4 2.7 GO:0071321 cellular response to cGMP(GO:0071321)
0.4 1.5 GO:0001928 regulation of exocyst assembly(GO:0001928)
0.4 1.1 GO:0061623 glycolytic process from galactose(GO:0061623)
0.4 1.5 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.4 1.4 GO:0032915 positive regulation of transforming growth factor beta2 production(GO:0032915)
0.4 0.7 GO:0060423 foregut regionalization(GO:0060423) lung field specification(GO:0060424) lung induction(GO:0060492)
0.4 4.3 GO:0006020 inositol metabolic process(GO:0006020)
0.4 1.1 GO:2000538 regulation of cGMP-mediated signaling(GO:0010752) regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538)
0.4 2.5 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.3 1.7 GO:0046341 CDP-diacylglycerol metabolic process(GO:0046341)
0.3 2.4 GO:0036216 response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109)
0.3 2.7 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
0.3 2.4 GO:0036438 maintenance of lens transparency(GO:0036438)
0.3 1.3 GO:2001287 negative regulation of caveolin-mediated endocytosis(GO:2001287)
0.3 1.2 GO:0050428 purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
0.3 0.6 GO:0060715 syncytiotrophoblast cell differentiation involved in labyrinthine layer development(GO:0060715)
0.3 1.5 GO:0042494 detection of bacterial lipoprotein(GO:0042494)
0.3 1.5 GO:0006680 glucosylceramide catabolic process(GO:0006680)
0.3 7.1 GO:0022010 central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291)
0.3 1.5 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.3 0.9 GO:0032976 release of matrix enzymes from mitochondria(GO:0032976) B cell receptor apoptotic signaling pathway(GO:1990117)
0.3 1.7 GO:0060082 response to carbon monoxide(GO:0034465) eye blink reflex(GO:0060082)
0.3 1.4 GO:0048165 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.3 2.2 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314) negative regulation of blood vessel remodeling(GO:0060313)
0.3 5.0 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.3 2.2 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.3 0.5 GO:0030997 regulation of centriole-centriole cohesion(GO:0030997)
0.3 1.6 GO:0099538 synaptic signaling via neuropeptide(GO:0099538) trans-synaptic signaling by neuropeptide(GO:0099540) trans-synaptic signaling by neuropeptide, modulating synaptic transmission(GO:0099551)
0.3 1.0 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.3 2.0 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.2 1.0 GO:0072275 metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277)
0.2 1.0 GO:0060598 dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis(GO:0060598)
0.2 1.2 GO:0051661 maintenance of centrosome location(GO:0051661)
0.2 2.3 GO:0034144 negative regulation of toll-like receptor 4 signaling pathway(GO:0034144)
0.2 0.7 GO:0001807 regulation of type IV hypersensitivity(GO:0001807)
0.2 0.7 GO:0060060 post-embryonic retina morphogenesis in camera-type eye(GO:0060060)
0.2 1.1 GO:0007223 Wnt signaling pathway, calcium modulating pathway(GO:0007223)
0.2 0.7 GO:1904719 excitatory chemical synaptic transmission(GO:0098976) positive regulation of AMPA glutamate receptor clustering(GO:1904719)
0.2 2.7 GO:0033689 negative regulation of osteoblast proliferation(GO:0033689)
0.2 4.0 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.2 1.1 GO:0098971 anterograde dendritic transport of neurotransmitter receptor complex(GO:0098971)
0.2 1.1 GO:0034224 cellular response to zinc ion starvation(GO:0034224)
0.2 4.0 GO:1903818 positive regulation of voltage-gated potassium channel activity(GO:1903818)
0.2 1.0 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.2 0.8 GO:0034499 late endosome to Golgi transport(GO:0034499)
0.2 0.6 GO:0019388 galactose catabolic process(GO:0019388)
0.2 0.4 GO:2000017 positive regulation of determination of dorsal identity(GO:2000017)
0.2 1.2 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.2 1.0 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.2 2.3 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.2 3.2 GO:0051546 keratinocyte migration(GO:0051546)
0.2 1.1 GO:0035860 esophagus smooth muscle contraction(GO:0014846) glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.2 0.9 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.2 2.8 GO:1904259 regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
0.2 0.7 GO:1904428 negative regulation of tubulin deacetylation(GO:1904428)
0.2 0.9 GO:0009153 purine deoxyribonucleotide biosynthetic process(GO:0009153)
0.2 2.7 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.2 1.0 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.2 2.2 GO:0070072 vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.2 0.7 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.2 8.2 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.2 0.5 GO:0003134 BMP signaling pathway involved in heart induction(GO:0003130) endodermal-mesodermal cell signaling(GO:0003133) endodermal-mesodermal cell signaling involved in heart induction(GO:0003134)
0.2 0.8 GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.2 0.8 GO:0070829 heterochromatin maintenance(GO:0070829)
0.2 0.6 GO:0071544 diphosphoinositol polyphosphate catabolic process(GO:0071544)
0.2 2.6 GO:0061339 establishment or maintenance of monopolar cell polarity(GO:0061339)
0.2 0.8 GO:0002121 inter-male aggressive behavior(GO:0002121)
0.2 0.6 GO:0097117 guanylate kinase-associated protein clustering(GO:0097117) regulation of AMPA glutamate receptor clustering(GO:1904717)
0.1 1.0 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.1 0.9 GO:0071421 manganese ion transmembrane transport(GO:0071421)
0.1 1.0 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.1 5.8 GO:0001921 positive regulation of receptor recycling(GO:0001921)
0.1 1.4 GO:1903753 negative regulation of p38MAPK cascade(GO:1903753)
0.1 0.6 GO:1903215 negative regulation of protein targeting to mitochondrion(GO:1903215)
0.1 0.7 GO:0060356 leucine import(GO:0060356)
0.1 1.1 GO:0051775 response to redox state(GO:0051775)
0.1 4.0 GO:0095500 acetylcholine receptor signaling pathway(GO:0095500) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
0.1 1.9 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 3.5 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.1 0.5 GO:0032972 regulation of muscle filament sliding speed(GO:0032972)
0.1 0.5 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.1 1.1 GO:0090500 endocardial cushion to mesenchymal transition(GO:0090500)
0.1 1.8 GO:0042048 olfactory behavior(GO:0042048)
0.1 0.3 GO:1902512 positive regulation of apoptotic DNA fragmentation(GO:1902512)
0.1 1.4 GO:0036158 outer dynein arm assembly(GO:0036158)
0.1 1.6 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.1 0.9 GO:0043652 engulfment of apoptotic cell(GO:0043652)
0.1 0.3 GO:0061198 fungiform papilla formation(GO:0061198)
0.1 1.4 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.1 1.1 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.1 0.2 GO:1904580 regulation of intracellular mRNA localization(GO:1904580)
0.1 0.3 GO:0021759 globus pallidus development(GO:0021759)
0.1 0.3 GO:1900222 negative regulation of beta-amyloid clearance(GO:1900222)
0.1 1.2 GO:0021785 branchiomotor neuron axon guidance(GO:0021785)
0.1 0.3 GO:1903406 regulation of sodium:potassium-exchanging ATPase activity(GO:1903406)
0.1 0.9 GO:0038203 TORC2 signaling(GO:0038203)
0.1 0.3 GO:0046061 dATP catabolic process(GO:0046061)
0.1 1.1 GO:0010578 regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010578) positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010579)
0.1 0.4 GO:0060971 embryonic heart tube left/right pattern formation(GO:0060971)
0.1 0.4 GO:0060830 ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
0.1 0.7 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.1 2.9 GO:0015991 ATP hydrolysis coupled proton transport(GO:0015991)
0.1 0.4 GO:0071431 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.1 1.0 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.1 0.6 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.1 2.7 GO:0018345 protein palmitoylation(GO:0018345)
0.1 2.6 GO:0032060 bleb assembly(GO:0032060)
0.1 0.5 GO:0015692 vanadium ion transport(GO:0015676) lead ion transport(GO:0015692)
0.1 2.0 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.1 0.2 GO:0000448 cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000448)
0.1 0.6 GO:0030397 membrane disassembly(GO:0030397) nuclear envelope disassembly(GO:0051081)
0.1 0.2 GO:2001160 regulation of histone H3-K79 methylation(GO:2001160)
0.1 0.3 GO:0015867 ATP transport(GO:0015867)
0.1 1.4 GO:1900003 regulation of serine-type endopeptidase activity(GO:1900003) negative regulation of serine-type endopeptidase activity(GO:1900004) regulation of serine-type peptidase activity(GO:1902571) negative regulation of serine-type peptidase activity(GO:1902572)
0.1 0.8 GO:1903551 regulation of extracellular exosome assembly(GO:1903551)
0.1 0.4 GO:0001830 trophectodermal cell fate commitment(GO:0001830)
0.1 2.2 GO:0032897 negative regulation of viral transcription(GO:0032897)
0.1 0.4 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.1 0.9 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.1 2.5 GO:0006198 cAMP catabolic process(GO:0006198)
0.1 0.6 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.1 1.2 GO:1900121 negative regulation of receptor binding(GO:1900121)
0.1 0.1 GO:0044830 modulation by host of viral RNA genome replication(GO:0044830)
0.1 0.3 GO:0055048 regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846)
0.1 0.2 GO:0032066 nucleolus to nucleoplasm transport(GO:0032066)
0.1 0.9 GO:0099515 actin filament-based transport(GO:0099515)
0.1 0.6 GO:0006108 malate metabolic process(GO:0006108)
0.1 0.7 GO:0071044 histone mRNA catabolic process(GO:0071044)
0.1 0.8 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.1 0.8 GO:0030322 stabilization of membrane potential(GO:0030322)
0.1 2.5 GO:0034308 primary alcohol metabolic process(GO:0034308)
0.1 8.0 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.1 0.8 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.1 2.3 GO:0061099 positive regulation of protein tyrosine kinase activity(GO:0061098) negative regulation of protein tyrosine kinase activity(GO:0061099)
0.1 2.0 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.1 0.7 GO:0006751 glutathione catabolic process(GO:0006751)
0.1 2.4 GO:2000171 negative regulation of dendrite development(GO:2000171)
0.1 3.5 GO:0070830 bicellular tight junction assembly(GO:0070830)
0.1 1.4 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.1 0.2 GO:0010593 negative regulation of lamellipodium assembly(GO:0010593) positive regulation of NMDA glutamate receptor activity(GO:1904783) regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000769) positive regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000771)
0.1 0.4 GO:1903232 melanosome assembly(GO:1903232)
0.0 0.3 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.0 0.5 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.0 0.4 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 0.5 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.0 1.5 GO:0002052 positive regulation of neuroblast proliferation(GO:0002052)
0.0 0.9 GO:0051382 kinetochore assembly(GO:0051382)
0.0 0.2 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.3 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.0 0.5 GO:0042135 neurotransmitter catabolic process(GO:0042135)
0.0 0.3 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.0 0.2 GO:0001844 protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:0001844)
0.0 0.3 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 1.4 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0 1.2 GO:0097320 membrane tubulation(GO:0097320)
0.0 4.9 GO:0019882 antigen processing and presentation(GO:0019882)
0.0 5.3 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.0 1.2 GO:1902259 regulation of delayed rectifier potassium channel activity(GO:1902259)
0.0 3.1 GO:0006497 protein lipidation(GO:0006497)
0.0 0.1 GO:0050915 sensory perception of sour taste(GO:0050915)
0.0 0.1 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.0 0.1 GO:0035795 negative regulation of mitochondrial membrane permeability(GO:0035795)
0.0 0.4 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.8 GO:0030497 fatty acid elongation(GO:0030497)
0.0 0.6 GO:0090026 positive regulation of monocyte chemotaxis(GO:0090026)
0.0 0.2 GO:0044154 histone H3-K14 acetylation(GO:0044154)
0.0 0.1 GO:0008292 acetylcholine biosynthetic process(GO:0008292) acetate ester biosynthetic process(GO:1900620)
0.0 0.8 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)
0.0 0.9 GO:0033235 positive regulation of protein sumoylation(GO:0033235)
0.0 4.6 GO:0071805 cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
0.0 1.5 GO:0061049 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.6 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.1 GO:1902528 regulation of protein linear polyubiquitination(GO:1902528) positive regulation of protein linear polyubiquitination(GO:1902530)
0.0 1.0 GO:0035767 endothelial cell chemotaxis(GO:0035767)
0.0 0.3 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 1.2 GO:2000179 positive regulation of neural precursor cell proliferation(GO:2000179)
0.0 0.8 GO:0045187 regulation of circadian sleep/wake cycle, sleep(GO:0045187)
0.0 2.0 GO:0046847 filopodium assembly(GO:0046847)
0.0 0.4 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.0 1.5 GO:0042982 amyloid precursor protein metabolic process(GO:0042982)
0.0 0.5 GO:0006047 UDP-N-acetylglucosamine metabolic process(GO:0006047)
0.0 0.2 GO:0070253 somatostatin secretion(GO:0070253)
0.0 0.7 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.0 0.9 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.0 0.3 GO:0090161 Golgi ribbon formation(GO:0090161)
0.0 2.3 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 0.1 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 1.5 GO:0051966 regulation of synaptic transmission, glutamatergic(GO:0051966)
0.0 0.3 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 4.7 GO:0030308 negative regulation of cell growth(GO:0030308)
0.0 0.7 GO:0006182 cGMP biosynthetic process(GO:0006182)
0.0 0.3 GO:1904869 protein localization to nuclear body(GO:1903405) protein localization to Cajal body(GO:1904867) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871)
0.0 3.2 GO:0006821 chloride transport(GO:0006821)
0.0 0.2 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.0 0.2 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.0 3.1 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 0.1 GO:0097309 cap1 mRNA methylation(GO:0097309)
0.0 0.3 GO:0097062 dendritic spine maintenance(GO:0097062)
0.0 0.8 GO:0071384 cellular response to corticosteroid stimulus(GO:0071384) cellular response to glucocorticoid stimulus(GO:0071385)
0.0 1.5 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.0 1.2 GO:0034605 cellular response to heat(GO:0034605)
0.0 0.7 GO:1903318 negative regulation of protein processing(GO:0010955) negative regulation of protein maturation(GO:1903318)
0.0 1.5 GO:0003073 regulation of systemic arterial blood pressure(GO:0003073)
0.0 0.9 GO:0006493 protein O-linked glycosylation(GO:0006493)
0.0 1.1 GO:0030071 regulation of mitotic metaphase/anaphase transition(GO:0030071)
0.0 0.3 GO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.0 0.1 GO:0000414 regulation of histone H3-K36 methylation(GO:0000414)
0.0 0.6 GO:0019835 cytolysis(GO:0019835)
0.0 0.7 GO:0007520 myoblast fusion(GO:0007520)
0.0 1.1 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.9 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.0 0.3 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.3 GO:0060716 labyrinthine layer blood vessel development(GO:0060716)
0.0 0.8 GO:0050909 sensory perception of taste(GO:0050909)
0.0 2.6 GO:0050808 synapse organization(GO:0050808)
0.0 0.1 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0 1.1 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436)
0.0 0.8 GO:0030500 regulation of bone mineralization(GO:0030500)
0.0 0.5 GO:0009247 glycolipid biosynthetic process(GO:0009247)
0.0 0.5 GO:0009408 response to heat(GO:0009408)
0.0 0.1 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.0 1.6 GO:0001890 placenta development(GO:0001890)
0.0 1.7 GO:0009636 response to toxic substance(GO:0009636)
0.0 1.6 GO:0030509 BMP signaling pathway(GO:0030509)
0.0 0.5 GO:0032784 regulation of DNA-templated transcription, elongation(GO:0032784)
0.0 1.0 GO:0046488 phosphatidylinositol metabolic process(GO:0046488)
0.0 0.4 GO:0010830 regulation of myotube differentiation(GO:0010830)
0.0 0.5 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.2 GO:0034453 microtubule anchoring(GO:0034453)
0.0 0.1 GO:0000492 box C/D snoRNP assembly(GO:0000492)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 5.8 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
1.1 4.5 GO:0099573 glutamatergic postsynaptic density(GO:0099573)
0.8 11.7 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.7 5.6 GO:0098574 cytoplasmic side of lysosomal membrane(GO:0098574)
0.7 2.8 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.7 2.7 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.6 1.7 GO:0098855 HCN channel complex(GO:0098855)
0.5 3.2 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.4 2.2 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.3 1.3 GO:0019034 viral replication complex(GO:0019034) dendritic filopodium(GO:1902737)
0.3 0.9 GO:0097144 BAX complex(GO:0097144)
0.3 2.5 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.3 2.2 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.3 1.3 GO:0044393 microspike(GO:0044393)
0.2 5.2 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.2 7.6 GO:0005921 gap junction(GO:0005921)
0.2 2.1 GO:0044327 dendritic spine head(GO:0044327)
0.2 1.0 GO:0061689 tricellular tight junction(GO:0061689)
0.2 3.4 GO:0071437 invadopodium(GO:0071437)
0.1 3.0 GO:0042599 lamellar body(GO:0042599)
0.1 1.0 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.1 0.6 GO:0032127 dense core granule membrane(GO:0032127)
0.1 0.6 GO:0071920 cleavage body(GO:0071920)
0.1 2.8 GO:0045180 basal cortex(GO:0045180)
0.1 1.4 GO:0036157 outer dynein arm(GO:0036157)
0.1 0.7 GO:1990745 GARP complex(GO:0000938) EARP complex(GO:1990745)
0.1 3.1 GO:0032433 filopodium tip(GO:0032433)
0.1 0.4 GO:0048179 activin receptor complex(GO:0048179)
0.1 3.3 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.1 2.2 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.1 16.8 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.1 1.2 GO:0043083 synaptic cleft(GO:0043083)
0.1 3.5 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 1.1 GO:1990075 periciliary membrane compartment(GO:1990075)
0.1 2.9 GO:0033178 proton-transporting two-sector ATPase complex, catalytic domain(GO:0033178)
0.1 2.6 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 0.7 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.1 0.4 GO:0097543 ciliary inversin compartment(GO:0097543)
0.1 4.5 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 0.3 GO:0005608 laminin-3 complex(GO:0005608)
0.1 1.7 GO:0005766 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.1 1.3 GO:0016589 NURF complex(GO:0016589)
0.1 2.0 GO:0000145 exocyst(GO:0000145)
0.1 0.4 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.1 1.7 GO:0031143 pseudopodium(GO:0031143)
0.1 2.6 GO:0043218 compact myelin(GO:0043218)
0.1 0.5 GO:0070826 paraferritin complex(GO:0070826)
0.1 2.8 GO:0030057 desmosome(GO:0030057)
0.1 1.4 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.1 9.1 GO:0005795 Golgi stack(GO:0005795)
0.1 0.8 GO:0031931 TORC1 complex(GO:0031931)
0.1 0.5 GO:1990584 cardiac Troponin complex(GO:1990584)
0.1 0.3 GO:0097165 nuclear stress granule(GO:0097165)
0.1 0.5 GO:0032584 growth cone membrane(GO:0032584)
0.1 3.8 GO:0048786 presynaptic active zone(GO:0048786)
0.1 1.8 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.1 0.3 GO:0055028 cortical microtubule(GO:0055028)
0.1 1.0 GO:0031258 lamellipodium membrane(GO:0031258)
0.1 0.6 GO:0061574 ASAP complex(GO:0061574)
0.1 1.3 GO:0030128 clathrin coat of endocytic vesicle(GO:0030128)
0.1 0.9 GO:0070852 cell body fiber(GO:0070852)
0.1 0.4 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.1 1.1 GO:0030127 COPII vesicle coat(GO:0030127)
0.1 1.2 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1 0.8 GO:0000788 nuclear nucleosome(GO:0000788)
0.1 0.3 GO:0008290 F-actin capping protein complex(GO:0008290)
0.1 0.8 GO:0000813 ESCRT I complex(GO:0000813)
0.1 3.0 GO:0031901 early endosome membrane(GO:0031901)
0.1 0.4 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.1 6.8 GO:0043197 dendritic spine(GO:0043197)
0.1 1.2 GO:0001891 phagocytic cup(GO:0001891)
0.0 1.1 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.4 GO:0033503 HULC complex(GO:0033503)
0.0 5.8 GO:0030175 filopodium(GO:0030175)
0.0 0.9 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 1.2 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.9 GO:0060076 excitatory synapse(GO:0060076)
0.0 1.2 GO:0030137 COPI-coated vesicle(GO:0030137)
0.0 6.9 GO:0070160 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 16.1 GO:0014069 postsynaptic density(GO:0014069)
0.0 3.2 GO:0034707 chloride channel complex(GO:0034707)
0.0 1.4 GO:0005865 striated muscle thin filament(GO:0005865)
0.0 1.2 GO:0099738 cell cortex region(GO:0099738)
0.0 0.7 GO:0032039 integrator complex(GO:0032039)
0.0 1.0 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 1.3 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 0.1 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0 2.8 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 2.5 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 1.4 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.4 GO:0005845 mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518) messenger ribonucleoprotein complex(GO:1990124)
0.0 0.5 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 4.5 GO:0008021 synaptic vesicle(GO:0008021)
0.0 0.2 GO:0044530 supraspliceosomal complex(GO:0044530)
0.0 0.2 GO:0070545 PeBoW complex(GO:0070545)
0.0 0.2 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.4 GO:0042555 MCM complex(GO:0042555)
0.0 5.2 GO:0043209 myelin sheath(GO:0043209)
0.0 3.1 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.8 GO:0034706 sodium channel complex(GO:0034706)
0.0 2.3 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.4 GO:0045277 respiratory chain complex IV(GO:0045277)
0.0 0.2 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.2 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.4 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.3 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.0 0.2 GO:0097470 ribbon synapse(GO:0097470)
0.0 0.1 GO:0042827 platelet dense granule(GO:0042827)
0.0 0.1 GO:0034448 EGO complex(GO:0034448)
0.0 0.3 GO:0044295 axonal growth cone(GO:0044295)
0.0 2.2 GO:0030027 lamellipodium(GO:0030027)
0.0 0.5 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 0.9 GO:0032420 stereocilium(GO:0032420)
0.0 1.0 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 0.2 GO:0071141 SMAD protein complex(GO:0071141)
0.0 1.1 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 7.2 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 0.4 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.3 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.4 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.6 GO:0016235 aggresome(GO:0016235)
0.0 1.3 GO:0005882 intermediate filament(GO:0005882)
0.0 0.3 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 11.3 GO:0009986 cell surface(GO:0009986)
0.0 0.4 GO:0097546 ciliary base(GO:0097546)
0.0 1.4 GO:0016605 PML body(GO:0016605)
0.0 0.2 GO:0043034 costamere(GO:0043034)
0.0 0.2 GO:0031082 BLOC complex(GO:0031082)
0.0 0.8 GO:0005884 actin filament(GO:0005884)
0.0 1.1 GO:0045211 postsynaptic membrane(GO:0045211)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 7.4 GO:0030549 acetylcholine receptor activator activity(GO:0030549)
1.0 3.0 GO:1990698 palmitoleoyltransferase activity(GO:1990698)
0.7 5.2 GO:0031812 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.7 2.7 GO:1990763 arrestin family protein binding(GO:1990763)
0.7 3.3 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.6 1.8 GO:0031768 ghrelin receptor binding(GO:0031768)
0.6 3.5 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.6 1.7 GO:0003881 CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity(GO:0003881)
0.5 1.5 GO:0004348 glucosylceramidase activity(GO:0004348)
0.5 3.0 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
0.5 2.9 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.5 4.3 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.5 1.4 GO:0035939 microsatellite binding(GO:0035939)
0.5 1.9 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.4 1.7 GO:0015057 thrombin receptor activity(GO:0015057)
0.4 1.2 GO:0016501 prostacyclin receptor activity(GO:0016501)
0.4 4.0 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.4 1.6 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.4 1.5 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.4 1.8 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.4 2.5 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.3 1.0 GO:0001888 glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0001888)
0.3 1.7 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.3 1.7 GO:0005275 amine transmembrane transporter activity(GO:0005275)
0.3 1.3 GO:0008147 structural constituent of bone(GO:0008147)
0.3 5.7 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.3 1.0 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.3 4.9 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.3 3.3 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.3 6.6 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.3 1.2 GO:0004779 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.3 1.5 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.3 1.8 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.3 1.7 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.3 1.7 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.3 4.5 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.3 2.8 GO:1903136 cuprous ion binding(GO:1903136)
0.3 1.1 GO:0031800 type 3 metabotropic glutamate receptor binding(GO:0031800)
0.3 0.8 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.3 1.6 GO:0060175 brain-derived neurotrophic factor-activated receptor activity(GO:0060175)
0.3 2.1 GO:0017040 ceramidase activity(GO:0017040)
0.2 6.4 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.2 1.0 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.2 1.5 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.2 2.9 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.2 1.2 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.2 9.8 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.2 0.7 GO:0042015 interleukin-20 binding(GO:0042015)
0.2 0.9 GO:0051381 histamine binding(GO:0051381)
0.2 1.9 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.2 1.7 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.2 6.1 GO:0031489 myosin V binding(GO:0031489)
0.2 0.8 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.2 0.6 GO:0004471 malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.2 0.7 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733)
0.2 11.7 GO:0008307 structural constituent of muscle(GO:0008307)
0.2 0.7 GO:0004609 phosphatidylserine decarboxylase activity(GO:0004609)
0.2 1.6 GO:0045504 dynein heavy chain binding(GO:0045504)
0.2 2.1 GO:0019966 interleukin-1 binding(GO:0019966)
0.2 1.1 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.2 5.1 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.2 1.1 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.1 1.0 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.1 6.3 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.1 1.9 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.1 3.1 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 3.4 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.1 1.1 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.1 1.1 GO:0004859 phospholipase inhibitor activity(GO:0004859)
0.1 1.4 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.1 5.0 GO:0043236 laminin binding(GO:0043236)
0.1 0.5 GO:0035276 calcium-independent protein kinase C activity(GO:0004699) ethanol binding(GO:0035276)
0.1 0.6 GO:0033677 DNA/RNA helicase activity(GO:0033677)
0.1 0.9 GO:0001849 complement component C1q binding(GO:0001849)
0.1 2.0 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.1 0.3 GO:0097677 STAT family protein binding(GO:0097677)
0.1 0.7 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.1 1.0 GO:0017050 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.1 0.3 GO:0052692 raffinose alpha-galactosidase activity(GO:0052692)
0.1 13.2 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 0.3 GO:0035851 Krueppel-associated box domain binding(GO:0035851)
0.1 1.0 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 0.5 GO:0008761 UDP-N-acetylglucosamine 2-epimerase activity(GO:0008761)
0.1 2.5 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.1 1.6 GO:0042809 vitamin D receptor binding(GO:0042809)
0.1 1.1 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.1 9.8 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.1 2.6 GO:0015026 coreceptor activity(GO:0015026)
0.1 3.0 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1 0.6 GO:0008486 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.1 1.4 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 2.0 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1 0.6 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.1 1.6 GO:0033549 MAP kinase phosphatase activity(GO:0033549)
0.1 0.9 GO:0051434 BH3 domain binding(GO:0051434)
0.1 6.6 GO:0048365 Rac GTPase binding(GO:0048365)
0.1 0.4 GO:0047635 L-alanine:2-oxoglutarate aminotransferase activity(GO:0004021) alanine-oxo-acid transaminase activity(GO:0047635)
0.1 0.5 GO:0015639 cadmium ion transmembrane transporter activity(GO:0015086) lead ion transmembrane transporter activity(GO:0015094) vanadium ion transmembrane transporter activity(GO:0015100) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.1 0.5 GO:0019211 phosphatase activator activity(GO:0019211)
0.1 3.4 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.1 0.2 GO:0004637 phosphoribosylamine-glycine ligase activity(GO:0004637)
0.1 1.7 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.1 0.3 GO:0047874 dolichyldiphosphatase activity(GO:0047874)
0.1 1.0 GO:0017147 Wnt-protein binding(GO:0017147)
0.1 1.0 GO:0015377 cation:chloride symporter activity(GO:0015377)
0.1 0.4 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.1 0.3 GO:0048019 receptor antagonist activity(GO:0048019)
0.1 2.3 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.1 1.5 GO:0030275 LRR domain binding(GO:0030275)
0.1 2.9 GO:0070412 R-SMAD binding(GO:0070412)
0.1 1.7 GO:0005351 sugar:proton symporter activity(GO:0005351)
0.1 0.8 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 0.8 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.1 0.2 GO:0004566 beta-glucuronidase activity(GO:0004566)
0.1 2.2 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.1 0.6 GO:0034452 dynactin binding(GO:0034452)
0.1 0.4 GO:0097016 L27 domain binding(GO:0097016)
0.1 0.8 GO:0019957 C-C chemokine binding(GO:0019957)
0.1 0.7 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.1 1.0 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.1 0.9 GO:0004385 guanylate kinase activity(GO:0004385)
0.1 1.2 GO:0034483 heparan sulfate sulfotransferase activity(GO:0034483)
0.1 2.2 GO:0043014 alpha-tubulin binding(GO:0043014)
0.1 1.4 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.2 GO:0019828 aspartic-type endopeptidase inhibitor activity(GO:0019828)
0.0 0.2 GO:0070728 leucine binding(GO:0070728)
0.0 1.1 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.4 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.9 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.3 GO:0031749 D2 dopamine receptor binding(GO:0031749)
0.0 0.5 GO:0043495 protein anchor(GO:0043495)
0.0 0.3 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.3 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 6.1 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 2.7 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.8 GO:0004622 lysophospholipase activity(GO:0004622)
0.0 0.1 GO:0005110 frizzled-2 binding(GO:0005110)
0.0 2.4 GO:0097110 scaffold protein binding(GO:0097110)
0.0 0.7 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.9 GO:0000146 microfilament motor activity(GO:0000146)
0.0 0.9 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.3 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.0 0.1 GO:0052833 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.0 0.4 GO:0000339 RNA cap binding(GO:0000339)
0.0 0.3 GO:0001055 RNA polymerase II activity(GO:0001055)
0.0 0.3 GO:0032554 purine deoxyribonucleotide binding(GO:0032554)
0.0 0.3 GO:0015217 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.0 0.5 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 0.4 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.9 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.3 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 0.4 GO:0034979 NAD-dependent protein deacetylase activity(GO:0034979)
0.0 1.1 GO:0008146 sulfotransferase activity(GO:0008146)
0.0 3.0 GO:0003774 motor activity(GO:0003774)
0.0 0.4 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 3.1 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 1.0 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 3.2 GO:0005254 chloride channel activity(GO:0005254)
0.0 0.6 GO:0017166 vinculin binding(GO:0017166)
0.0 0.5 GO:0048018 receptor agonist activity(GO:0048018)
0.0 4.5 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 0.4 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.1 GO:0033149 FFAT motif binding(GO:0033149)
0.0 0.3 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.2 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.0 7.0 GO:0030695 GTPase regulator activity(GO:0030695)
0.0 0.1 GO:0043426 MRF binding(GO:0043426)
0.0 0.3 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.0 0.7 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.1 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 2.6 GO:0005178 integrin binding(GO:0005178)
0.0 0.2 GO:0019956 chemokine binding(GO:0019956)
0.0 0.3 GO:0038191 neuropilin binding(GO:0038191)
0.0 3.2 GO:0051015 actin filament binding(GO:0051015)
0.0 0.1 GO:0019158 fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0 0.1 GO:0004483 mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483)
0.0 0.7 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 3.7 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 1.3 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.6 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.9 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 0.1 GO:0015220 choline transmembrane transporter activity(GO:0015220) choline binding(GO:0033265)
0.0 0.0 GO:0051538 3 iron, 4 sulfur cluster binding(GO:0051538)
0.0 0.5 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.0 GO:0004948 calcitonin receptor activity(GO:0004948)
0.0 0.4 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.5 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.3 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 3.3 GO:0003924 GTPase activity(GO:0003924)
0.0 0.1 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 0.5 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.8 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors(GO:0016627)
0.0 0.1 GO:0015280 ligand-gated sodium channel activity(GO:0015280)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 4.3 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.2 1.0 PID WNT SIGNALING PATHWAY Wnt signaling network
0.2 6.8 ST GA12 PATHWAY G alpha 12 Pathway
0.2 9.8 PID NETRIN PATHWAY Netrin-mediated signaling events
0.1 3.3 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.1 4.6 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.1 4.0 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.1 0.4 PID ALK2 PATHWAY ALK2 signaling events
0.1 5.4 PID BMP PATHWAY BMP receptor signaling
0.1 3.6 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.1 0.9 ST JAK STAT PATHWAY Jak-STAT Pathway
0.0 2.4 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 10.3 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.2 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 0.9 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 1.3 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 5.8 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 0.3 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.0 0.9 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.9 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.7 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 2.2 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 1.5 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.8 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 1.1 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.0 1.1 PID SHP2 PATHWAY SHP2 signaling
0.0 2.0 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 8.8 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 6.4 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.2 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.1 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 1.4 PID CDC42 PATHWAY CDC42 signaling events
0.0 0.6 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.4 PID ARF 3PATHWAY Arf1 pathway
0.0 1.5 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.9 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.3 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.6 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.6 PID HNF3A PATHWAY FOXA1 transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 5.8 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.3 8.4 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.2 11.7 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.2 5.7 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.2 4.4 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.2 4.8 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.2 4.4 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.2 2.7 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.1 1.9 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1 8.8 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.1 1.0 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.1 3.5 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1 3.0 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1 1.8 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.1 3.0 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.1 3.5 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.1 2.8 REACTOME AMYLOIDS Genes involved in Amyloids
0.1 1.7 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.1 4.6 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.1 1.6 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.1 4.0 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.1 1.2 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.1 3.6 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.1 1.8 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.1 1.7 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 3.2 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.1 1.2 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.1 3.9 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.1 1.9 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.1 4.3 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.1 0.9 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.1 0.8 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.1 0.8 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1 1.0 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.1 0.6 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.1 0.1 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0 1.6 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 3.7 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.0 1.2 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 1.9 REACTOME SPHINGOLIPID METABOLISM Genes involved in Sphingolipid metabolism
0.0 1.1 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.0 1.1 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.4 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.4 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.0 0.6 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 8.1 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.3 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 1.4 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0 1.2 REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.0 0.4 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.8 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 1.5 REACTOME SIGNAL TRANSDUCTION BY L1 Genes involved in Signal transduction by L1
0.0 1.0 REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.0 1.0 REACTOME SIGNALING BY NOTCH1 Genes involved in Signaling by NOTCH1
0.0 0.4 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 2.1 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels
0.0 0.8 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 0.7 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.0 2.6 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.8 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.6 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.3 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.4 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 1.7 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 0.7 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.3 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 1.0 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 0.6 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.3 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.5 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 1.0 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.3 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.0 0.6 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.6 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.3 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 0.5 REACTOME MUSCLE CONTRACTION Genes involved in Muscle contraction
0.0 0.1 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.1 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling