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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Tfap2b

Z-value: 1.00

Motif logo

Transcription factors associated with Tfap2b

Gene Symbol Gene ID Gene Info
ENSMUSG00000025927.14 Tfap2b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Tfap2bmm39_v1_chr1_+_19279138_19279176-0.191.2e-01Click!

Activity profile of Tfap2b motif

Sorted Z-values of Tfap2b motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Tfap2b

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr1_+_131671751 8.89 ENSMUST00000049027.10
solute carrier family 26, member 9
chr11_-_99383938 7.83 ENSMUST00000006969.8
keratin 23
chr15_-_101862711 5.90 ENSMUST00000164932.3
keratin 78
chr7_+_24335969 5.60 ENSMUST00000080718.6
Ly6/Plaur domain containing 3
chr4_-_140501507 4.95 ENSMUST00000026381.7
peptidyl arginine deiminase, type IV
chr13_+_3887757 4.70 ENSMUST00000042219.6
calmodulin 4
chr13_+_48816466 4.20 ENSMUST00000021813.5
BarH-like homeobox 1
chr11_-_70146156 4.15 ENSMUST00000108574.3
ENSMUST00000000329.9
arachidonate 12-lipoxygenase
chr1_+_131678223 3.94 ENSMUST00000147800.2
solute carrier family 26, member 9
chr15_-_101833160 3.67 ENSMUST00000023797.8
keratin 4
chr18_-_20247666 3.29 ENSMUST00000224432.2
desmocollin 1
chr18_-_20247824 3.03 ENSMUST00000038710.6
desmocollin 1
chr19_+_6952319 2.93 ENSMUST00000070850.8
protein phosphatase 1, regulatory inhibitor subunit 14B
chr3_-_84387700 2.86 ENSMUST00000194027.2
ENSMUST00000107689.7
FH2 domain containing 1
chr6_+_113435716 2.85 ENSMUST00000203661.3
ENSMUST00000204774.3
ENSMUST00000053569.7
ENSMUST00000101065.8
interleukin 17 receptor E
chr19_+_6952580 2.79 ENSMUST00000237084.2
ENSMUST00000236218.2
ENSMUST00000237235.2
protein phosphatase 1, regulatory inhibitor subunit 14B
chr7_+_43441315 2.72 ENSMUST00000005891.7
kallikrein related-peptidase 9
chr11_-_102255999 2.57 ENSMUST00000006749.10
solute carrier family 4 (anion exchanger), member 1
chr9_+_118881838 2.45 ENSMUST00000051386.13
ENSMUST00000074734.13
villin-like
chr6_-_124710084 2.29 ENSMUST00000112484.10
protein tyrosine phosphatase, non-receptor type 6
chr1_+_34840785 2.26 ENSMUST00000047664.16
ENSMUST00000211073.2
Rho guanine nucleotide exchange factor (GEF) 4
novel protein
chr18_-_20247928 2.24 ENSMUST00000226115.2
desmocollin 1
chr12_+_85733415 2.04 ENSMUST00000040536.6
basic leucine zipper transcription factor, ATF-like
chr5_-_103777145 2.02 ENSMUST00000031263.2
solute carrier family 10 (sodium/bile acid cotransporter family), member 6
chr2_+_25179903 2.00 ENSMUST00000028337.7
leucine rich repeat containing 26
chr7_+_25386418 1.97 ENSMUST00000002678.10
transforming growth factor, beta 1
chr1_+_86454431 1.96 ENSMUST00000045897.15
ENSMUST00000186255.7
ENSMUST00000188699.7
prothymosin alpha
chr15_-_102165884 1.95 ENSMUST00000043172.15
retinoic acid receptor, gamma
chr11_+_69546140 1.95 ENSMUST00000047373.6
SRY (sex determining region Y)-box 15
chr9_+_118881926 1.90 ENSMUST00000131647.2
villin-like
chr3_-_137687284 1.87 ENSMUST00000136613.4
ENSMUST00000029806.13
dual adaptor for phosphotyrosine and 3-phosphoinositides 1
chr19_+_38043446 1.86 ENSMUST00000236044.2
ENSMUST00000116506.8
ENSMUST00000096096.12
ENSMUST00000169673.3
centrosomal protein 55
chr13_-_40891849 1.80 ENSMUST00000223869.2
transcription factor AP-2, alpha
chr4_-_133360749 1.79 ENSMUST00000084238.5
zinc finger, DHHC domain containing 18
chr10_-_81201642 1.74 ENSMUST00000020456.5
RIKEN cDNA 4930404N11 gene
chr15_-_102165740 1.73 ENSMUST00000135466.2
retinoic acid receptor, gamma
chr6_+_7844759 1.71 ENSMUST00000040159.6
core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1
chr7_-_45175570 1.67 ENSMUST00000167273.2
ENSMUST00000042105.11
protein phosphatase 1, regulatory subunit 15A
chr17_+_34809132 1.66 ENSMUST00000173772.2
G-protein signalling modulator 3 (AGS3-like, C. elegans)
chr15_-_75620060 1.65 ENSMUST00000062002.6
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein A (avian)
chr17_+_33774681 1.63 ENSMUST00000087605.13
ENSMUST00000174695.2
myosin IF
chr15_+_61859255 1.61 ENSMUST00000160009.2
myelocytomatosis oncogene
chr12_+_70872266 1.60 ENSMUST00000057859.9
FERM domain containing 6
chr18_+_61044830 1.59 ENSMUST00000040359.6
arylsulfatase i
chr7_-_97811525 1.58 ENSMUST00000107112.2
calpain 5
chr19_-_6065872 1.54 ENSMUST00000164843.10
calpain 1
chr12_-_111638722 1.52 ENSMUST00000001304.9
creatine kinase, brain
chr17_+_34808772 1.51 ENSMUST00000038244.15
G-protein signalling modulator 3 (AGS3-like, C. elegans)
chr1_+_86454511 1.51 ENSMUST00000188533.2
prothymosin alpha
chr4_-_133694607 1.50 ENSMUST00000105893.8
high mobility group nucleosomal binding domain 2
chr7_+_28834276 1.43 ENSMUST00000161522.8
ENSMUST00000204845.3
ENSMUST00000205027.3
ENSMUST00000204194.3
ENSMUST00000203070.3
ENSMUST00000203380.3
RAS guanyl releasing protein 4
chr8_+_72050292 1.42 ENSMUST00000143662.8
niban apoptosis regulator 3
chr6_+_97783975 1.42 ENSMUST00000203884.3
ENSMUST00000043637.14
melanogenesis associated transcription factor
chr8_+_85449632 1.40 ENSMUST00000098571.5
RIKEN cDNA G430095P16 gene
chr15_-_103242697 1.39 ENSMUST00000229373.2
zinc finger protein 385A
chr7_-_126046814 1.36 ENSMUST00000146973.2
ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
chr16_-_92155762 1.34 ENSMUST00000166707.3
potassium voltage-gated channel, Isk-related subfamily, member 1
chr2_+_158610003 1.34 ENSMUST00000029183.3
family with sequence similarity 83, member D
chr16_-_92156312 1.30 ENSMUST00000051705.7
potassium voltage-gated channel, Isk-related subfamily, member 1
chr1_+_74830675 1.29 ENSMUST00000006718.15
wingless-type MMTV integration site family, member 10A
chr2_-_131001916 1.28 ENSMUST00000103188.10
ENSMUST00000133602.8
ENSMUST00000028800.12
RIKEN cDNA 1700037H04 gene
chr16_-_20245138 1.28 ENSMUST00000079158.13
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
chr3_-_132655804 1.25 ENSMUST00000117164.8
ENSMUST00000093971.5
ENSMUST00000042729.16
nephronectin
chr9_-_50256268 1.23 ENSMUST00000076364.6
ribosomal protein L10, pseudogene 3
chr3_-_132655954 1.23 ENSMUST00000042744.16
ENSMUST00000117811.8
nephronectin
chrX_+_158410229 1.22 ENSMUST00000112456.9
SH3-domain kinase binding protein 1
chr7_+_141027557 1.22 ENSMUST00000106004.8
ribosomal protein, large P2
chr15_-_97729341 1.21 ENSMUST00000079838.14
ENSMUST00000118294.8
histone deacetylase 7
chr7_+_141027763 1.20 ENSMUST00000106003.2
ribosomal protein, large P2
chr18_+_60907698 1.20 ENSMUST00000118551.8
ribosomal protein S14
chr2_-_11506893 1.19 ENSMUST00000114845.10
ENSMUST00000171188.9
ENSMUST00000179584.8
ENSMUST00000028114.13
ENSMUST00000114846.9
ENSMUST00000170196.9
ENSMUST00000191668.6
ENSMUST00000049849.12
ENSMUST00000114844.8
ENSMUST00000100411.4
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
chr2_-_30720345 1.19 ENSMUST00000041726.4
ankyrin repeat and SOCS box-containing 6
chr12_-_15866763 1.19 ENSMUST00000020922.8
ENSMUST00000221215.2
ENSMUST00000221518.2
tribbles pseudokinase 2
chr14_+_54431947 1.19 ENSMUST00000103715.2
T cell receptor alpha joining 26
chr8_+_105897542 1.17 ENSMUST00000109394.3
core binding factor beta
chr4_-_133694543 1.15 ENSMUST00000123234.8
high mobility group nucleosomal binding domain 2
chr5_-_115439016 1.15 ENSMUST00000009157.4
dynein light chain LC8-type 1
chr18_+_60907668 1.15 ENSMUST00000025511.11
ribosomal protein S14
chr7_+_24990596 1.14 ENSMUST00000164820.2
capicua transcriptional repressor
chr16_-_20245071 1.14 ENSMUST00000115547.9
ENSMUST00000096199.5
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
chr4_+_59035088 1.14 ENSMUST00000041160.13
guanine nucleotide binding protein (G protein), gamma 10
chr12_-_76756772 1.13 ENSMUST00000166101.2
spectrin beta, erythrocytic
chr19_+_38043506 1.12 ENSMUST00000237408.2
centrosomal protein 55
chr8_-_91074971 1.09 ENSMUST00000109621.10
TOX high mobility group box family member 3
chrX_-_9335525 1.09 ENSMUST00000015484.10
cytochrome b-245, beta polypeptide
chr13_-_53440087 1.09 ENSMUST00000021918.10
receptor tyrosine kinase-like orphan receptor 2
chr7_+_58307930 1.08 ENSMUST00000168747.3
ATPase, class V, type 10A
chr8_+_105897300 1.06 ENSMUST00000052209.9
ENSMUST00000109392.9
ENSMUST00000109395.8
core binding factor beta
chr5_-_115438971 1.04 ENSMUST00000112090.2
dynein light chain LC8-type 1
chr3_+_130904000 1.02 ENSMUST00000029611.14
ENSMUST00000106341.9
ENSMUST00000066849.13
lymphoid enhancer binding factor 1
chr1_-_132294807 1.01 ENSMUST00000136828.3
transmembrane and coiled-coil domains 2
chr4_+_48045143 0.98 ENSMUST00000030025.10
nuclear receptor subfamily 4, group A, member 3
chr8_+_93084253 0.97 ENSMUST00000210246.2
ENSMUST00000034184.12
Iroquois homeobox 5
chr9_+_62249341 0.96 ENSMUST00000135395.8
acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
chr2_-_147887810 0.96 ENSMUST00000109964.8
forkhead box A2
chr19_+_6451667 0.96 ENSMUST00000113471.3
ENSMUST00000113469.3
RAS, guanyl releasing protein 2
chr3_-_108322868 0.95 ENSMUST00000090558.10
cadherin, EGF LAG seven-pass G-type receptor 2
chr4_-_133695264 0.94 ENSMUST00000102553.11
high mobility group nucleosomal binding domain 2
chr5_-_139798992 0.93 ENSMUST00000110832.8
transmembrane protein 184a
chr5_-_24534554 0.92 ENSMUST00000115098.7
potassium voltage-gated channel, subfamily H (eag-related), member 2
chr2_+_3714515 0.90 ENSMUST00000115053.9
family with sequence similarity 107, member B
chr17_-_71156639 0.89 ENSMUST00000134654.2
ENSMUST00000172229.8
ENSMUST00000127719.2
TGFB-induced factor homeobox 1
chr17_+_43327412 0.89 ENSMUST00000024708.6
tumor necrosis factor receptor superfamily, member 21
chr10_-_84938350 0.88 ENSMUST00000059383.8
ENSMUST00000216889.2
four and a half LIM domains 4
chr19_-_6065415 0.87 ENSMUST00000237519.2
calpain 1
chr8_+_106024294 0.87 ENSMUST00000015003.10
E2F transcription factor 4
chr18_+_82929451 0.85 ENSMUST00000235902.2
zinc finger protein 516
chr17_-_48189815 0.80 ENSMUST00000154108.2
forkhead box P4
chr17_+_29709723 0.80 ENSMUST00000024811.9
proviral integration site 1
chr1_-_135211813 0.79 ENSMUST00000077340.14
ENSMUST00000074357.8
arginyl aminopeptidase (aminopeptidase B)
chr5_+_149335214 0.79 ENSMUST00000093110.12
mesenteric estrogen dependent adipogenesis
chr7_+_127078371 0.78 ENSMUST00000205432.3
fibrosin
chr11_-_94133527 0.78 ENSMUST00000061469.4
WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2
chr14_-_86986541 0.78 ENSMUST00000226254.2
diaphanous related formin 3
chr15_+_102927366 0.77 ENSMUST00000165375.3
homeobox C4
chr11_-_100160697 0.77 ENSMUST00000017270.8
keratin 42
chr4_-_133695204 0.77 ENSMUST00000100472.10
ENSMUST00000136327.2
high mobility group nucleosomal binding domain 2
chr8_+_106412905 0.76 ENSMUST00000213019.2
capping protein regulator and myosin 1 linker 2
chr1_-_96799832 0.76 ENSMUST00000071985.6
solute carrier organic anion transporter family, member 4C1
chr14_-_30329765 0.75 ENSMUST00000112207.8
ENSMUST00000112206.8
ENSMUST00000112202.8
ENSMUST00000112203.2
protein kinase C, delta
chr7_-_66339319 0.74 ENSMUST00000124899.8
ankyrin repeat and SOCS box-containing 7
chr3_+_106943472 0.73 ENSMUST00000052718.5
potassium voltage-gated channel, shaker-related subfamily, member 3
chr2_+_60040231 0.73 ENSMUST00000102748.11
membrane associated ring-CH-type finger 7
chr9_+_62249730 0.73 ENSMUST00000156461.2
acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
chr2_-_154411765 0.72 ENSMUST00000103145.11
E2F transcription factor 1
chr12_+_108376801 0.71 ENSMUST00000054955.14
echinoderm microtubule associated protein like 1
chr10_-_116417333 0.70 ENSMUST00000218744.2
ENSMUST00000105267.8
ENSMUST00000105265.8
ENSMUST00000167706.8
ENSMUST00000168036.8
ENSMUST00000169921.8
ENSMUST00000020374.6
CCR4-NOT transcription complex, subunit 2
chr6_-_124710030 0.70 ENSMUST00000173647.2
protein tyrosine phosphatase, non-receptor type 6
chr4_+_41762309 0.70 ENSMUST00000108042.3
interleukin 11 receptor, alpha chain 1
chr5_+_91175323 0.69 ENSMUST00000202724.4
ENSMUST00000041516.9
epithelial mitogen
chr9_-_54554483 0.67 ENSMUST00000128163.8
acyl-CoA synthetase bubblegum family member 1
chr7_+_24981604 0.67 ENSMUST00000163320.8
ENSMUST00000005578.13
capicua transcriptional repressor
chr5_+_31070739 0.67 ENSMUST00000031055.8
elastin microfibril interfacer 1
chr15_+_103411461 0.66 ENSMUST00000023132.5
phosphodiesterase 1B, Ca2+-calmodulin dependent
chr7_+_87927293 0.65 ENSMUST00000032779.12
ENSMUST00000131108.9
ENSMUST00000128791.2
cathepsin C
chr11_-_50183129 0.64 ENSMUST00000059458.5
mastermind like transcriptional coactivator 1
chr1_+_39940043 0.63 ENSMUST00000168431.7
ENSMUST00000163854.9
mitogen-activated protein kinase kinase kinase kinase 4
chr13_+_13612136 0.63 ENSMUST00000005532.9
nidogen 1
chr10_-_121312212 0.63 ENSMUST00000026902.9
Ras association (RalGDS/AF-6) domain family member 3
chr4_-_133965683 0.63 ENSMUST00000030645.9
connector enhancer of kinase suppressor of Ras 1
chr7_+_140659038 0.62 ENSMUST00000159375.8
plakophilin 3
chr11_+_60590498 0.61 ENSMUST00000052346.10
LLGL1 scribble cell polarity complex component
chr6_-_39702381 0.60 ENSMUST00000002487.15
Braf transforming gene
chr11_+_60590584 0.60 ENSMUST00000108719.4
LLGL1 scribble cell polarity complex component
chr12_+_108376884 0.60 ENSMUST00000109857.8
echinoderm microtubule associated protein like 1
chr10_+_67371295 0.59 ENSMUST00000145754.8
ENSMUST00000145936.2
early growth response 2
chr16_-_20244631 0.58 ENSMUST00000077867.10
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
chr16_+_24266829 0.58 ENSMUST00000078988.10
LIM domain containing preferred translocation partner in lipoma
chr8_-_91074754 0.57 ENSMUST00000176034.2
ENSMUST00000176616.8
TOX high mobility group box family member 3
chr6_-_115652831 0.57 ENSMUST00000112949.8
v-raf-leukemia viral oncogene 1
chr7_+_89053562 0.56 ENSMUST00000058755.5
frizzled class receptor 4
chr8_+_40876827 0.56 ENSMUST00000049389.11
ENSMUST00000128166.8
ENSMUST00000167766.2
zinc finger, DHHC domain containing 2
chr7_-_97958679 0.56 ENSMUST00000033020.14
alkaline ceramidase 3
chr6_-_115653583 0.54 ENSMUST00000000451.14
v-raf-leukemia viral oncogene 1
chr17_+_69690018 0.54 ENSMUST00000112674.8
zinc finger and BTB domain containing 14
chr9_+_37400577 0.53 ENSMUST00000211060.2
ENSMUST00000239463.2
ENSMUST00000048604.8
Myb/SANT-like DNA-binding domain containing 2
chr11_+_35011953 0.53 ENSMUST00000069837.4
slit guidance ligand 3
chr10_-_59787646 0.53 ENSMUST00000020308.5
DNA-damage-inducible transcript 4
chr2_-_181335518 0.52 ENSMUST00000108776.8
ENSMUST00000108771.2
regulator of G-protein signaling 19
chr7_-_34353767 0.52 ENSMUST00000206501.2
ENSMUST00000108069.8
potassium channel tetramerisation domain containing 15
chr6_-_83654789 0.51 ENSMUST00000037882.8
CD207 antigen
chr17_+_87590308 0.51 ENSMUST00000041110.12
ENSMUST00000125875.8
tetratricopeptide repeat domain 7
chr8_+_106331866 0.50 ENSMUST00000043531.10
RHO family interacting cell polarization regulator 1
chr19_-_6065799 0.50 ENSMUST00000235138.2
calpain 1
chr19_+_53665719 0.49 ENSMUST00000164202.9
RNA binding motif protein 20
chr9_+_61280890 0.49 ENSMUST00000161689.8
transducin-like enhancer of split 3
chr7_+_79882609 0.47 ENSMUST00000062915.9
GDP-D-glucose phosphorylase 1
chr13_-_10410857 0.46 ENSMUST00000187510.7
cholinergic receptor, muscarinic 3, cardiac
chr4_+_155924181 0.46 ENSMUST00000030947.4
matrix-remodelling associated 8
chr11_+_121150798 0.45 ENSMUST00000106113.2
forkhead box K2
chr10_+_19232281 0.45 ENSMUST00000053225.7
oligodendrocyte transcription factor 3
chr1_+_55445033 0.44 ENSMUST00000042986.10
phospholipase C-like 1
chr17_-_13211374 0.43 ENSMUST00000159551.8
ENSMUST00000160781.8
Wilms tumour 1-associating protein
chr13_+_24685508 0.43 ENSMUST00000238974.2
RHO family interacting cell polarization regulator 2
chr2_+_152873772 0.41 ENSMUST00000037235.7
X-linked Kx blood group related 7
chr1_-_177085736 0.41 ENSMUST00000111159.2
thymoma viral proto-oncogene 3
chr1_-_22031718 0.40 ENSMUST00000029667.13
ENSMUST00000173058.8
ENSMUST00000173404.2
potassium voltage-gated channel, subfamily Q, member 5
chr10_-_119075910 0.40 ENSMUST00000020315.13
cullin associated and neddylation disassociated 1
chr2_-_155199300 0.40 ENSMUST00000165234.2
ENSMUST00000077626.13
phosphatidylinositol glycan anchor biosynthesis, class U
chr10_-_58511476 0.40 ENSMUST00000003312.5
ectodysplasin-A receptor
chr11_-_97635484 0.37 ENSMUST00000018691.9
phosphatidylinositol-5-phosphate 4-kinase, type II, beta
chr16_-_21982049 0.37 ENSMUST00000100052.11
insulin-like growth factor 2 mRNA binding protein 2
chr14_+_56122404 0.37 ENSMUST00000022831.5
KH and NYN domain containing
chr9_-_106762818 0.37 ENSMUST00000185707.2
RNA binding motif protein 15B
chr19_+_5790918 0.37 ENSMUST00000081496.6
latent transforming growth factor beta binding protein 3
chr15_-_60696790 0.36 ENSMUST00000100635.5
LRAT domain containing 1
chr6_-_71299184 0.36 ENSMUST00000173297.2
ENSMUST00000114188.3
SET and MYND domain containing 1
chr7_+_28834391 0.36 ENSMUST00000160194.8
RAS guanyl releasing protein 4
chr6_+_91492910 0.36 ENSMUST00000040607.6
LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated
chr10_-_116984386 0.35 ENSMUST00000020381.5
fibroblast growth factor receptor substrate 2
chr10_+_84938452 0.35 ENSMUST00000095383.6
transmembrane protein 263
chr17_+_87270504 0.35 ENSMUST00000024956.15
ras homolog family member Q
chr3_+_145823205 0.35 ENSMUST00000140214.3
mucolipin 3
chr2_-_11506511 0.34 ENSMUST00000183869.8
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
chrX_+_7439839 0.34 ENSMUST00000144719.9
ENSMUST00000234896.2
Foxp3 regulating long intergenic noncoding RNA
forkhead box P3
chr2_-_91854844 0.34 ENSMUST00000028663.5
cAMP responsive element binding protein 3-like 1
chr2_+_30176395 0.33 ENSMUST00000064447.12
nucleoporin 188
chr7_+_46025890 0.33 ENSMUST00000072514.3
myogenic differentiation 1
chr2_-_93787441 0.33 ENSMUST00000099689.5
predicted gene 13889
chr10_-_61288437 0.33 ENSMUST00000167087.2
ENSMUST00000020288.15
eukaryotic translation initiation factor 4E binding protein 2

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 5.0 GO:0036414 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.8 4.2 GO:0051122 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.7 3.7 GO:0003430 growth plate cartilage chondrocyte growth(GO:0003430)
0.7 2.0 GO:0019049 evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834) negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.6 1.9 GO:0048627 myoblast development(GO:0048627) positive regulation of G0 to G1 transition(GO:0070318)
0.6 12.8 GO:0008272 sulfate transport(GO:0008272)
0.6 1.7 GO:0060734 regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:0060734)
0.5 2.7 GO:2000721 positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000721)
0.5 1.9 GO:0032696 negative regulation of interleukin-13 production(GO:0032696)
0.5 1.4 GO:0051659 maintenance of mitochondrion location(GO:0051659) relaxation of skeletal muscle(GO:0090076)
0.4 1.6 GO:0090095 lactic acid secretion(GO:0046722) regulation of metanephric cap mesenchymal cell proliferation(GO:0090095) positive regulation of metanephric cap mesenchymal cell proliferation(GO:0090096)
0.4 1.2 GO:0045074 interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.4 3.0 GO:0033277 abortive mitotic cell cycle(GO:0033277)
0.4 1.1 GO:0071550 death-inducing signaling complex assembly(GO:0071550)
0.4 1.8 GO:0003409 optic cup structural organization(GO:0003409)
0.3 1.4 GO:0010609 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.3 1.6 GO:0007223 Wnt signaling pathway, calcium modulating pathway(GO:0007223)
0.3 1.0 GO:0045014 carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
0.3 0.8 GO:0032976 release of matrix enzymes from mitochondria(GO:0032976) B cell receptor apoptotic signaling pathway(GO:1990117)
0.3 2.6 GO:0015701 bicarbonate transport(GO:0015701)
0.3 0.8 GO:2000813 negative regulation of barbed-end actin filament capping(GO:2000813)
0.2 1.7 GO:0016266 O-glycan processing(GO:0016266)
0.2 1.0 GO:0032765 positive regulation of mast cell cytokine production(GO:0032765) regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.2 0.9 GO:2001107 negative regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001107)
0.2 0.9 GO:1902303 negative regulation of potassium ion export(GO:1902303)
0.2 1.6 GO:0003383 apical constriction(GO:0003383)
0.2 0.6 GO:0021666 rhombomere formation(GO:0021594) rhombomere 3 formation(GO:0021660) rhombomere 5 morphogenesis(GO:0021664) rhombomere 5 formation(GO:0021666)
0.2 0.8 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.2 0.8 GO:0060697 positive regulation of phospholipid catabolic process(GO:0060697)
0.2 0.7 GO:0071930 negative regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071930)
0.2 3.4 GO:1903818 positive regulation of voltage-gated potassium channel activity(GO:1903818)
0.2 0.5 GO:0070100 negative regulation of chemokine-mediated signaling pathway(GO:0070100)
0.2 0.6 GO:0003162 atrioventricular node development(GO:0003162)
0.2 0.9 GO:0033326 cerebrospinal fluid secretion(GO:0033326)
0.2 0.9 GO:0018992 germ-line sex determination(GO:0018992)
0.2 2.9 GO:0016540 protein autoprocessing(GO:0016540)
0.2 1.5 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.1 2.2 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.1 4.4 GO:0040034 regulation of development, heterochronic(GO:0040034)
0.1 3.2 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.1 1.1 GO:0097411 hypoxia-inducible factor-1alpha signaling pathway(GO:0097411)
0.1 2.0 GO:0072540 T-helper 17 cell lineage commitment(GO:0072540)
0.1 3.0 GO:0000920 cell separation after cytokinesis(GO:0000920)
0.1 0.8 GO:2000138 positive regulation of cell proliferation involved in heart morphogenesis(GO:2000138)
0.1 0.4 GO:0036363 transforming growth factor beta activation(GO:0036363) regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
0.1 3.5 GO:0043486 histone exchange(GO:0043486)
0.1 0.4 GO:0046619 optic placode formation involved in camera-type eye formation(GO:0046619)
0.1 0.3 GO:0002362 CD4-positive, CD25-positive, alpha-beta regulatory T cell lineage commitment(GO:0002362)
0.1 0.3 GO:0014908 myotube differentiation involved in skeletal muscle regeneration(GO:0014908)
0.1 0.2 GO:0030997 regulation of centriole-centriole cohesion(GO:0030997)
0.1 1.4 GO:0044336 canonical Wnt signaling pathway involved in negative regulation of apoptotic process(GO:0044336)
0.1 0.6 GO:0002159 desmosome assembly(GO:0002159)
0.1 0.3 GO:2000597 optic nerve formation(GO:0021634) optic chiasma development(GO:0061360) regulation of optic nerve formation(GO:2000595) positive regulation of optic nerve formation(GO:2000597)
0.1 0.9 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.1 0.2 GO:0061153 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.1 0.5 GO:0060857 establishment of glial blood-brain barrier(GO:0060857)
0.1 0.4 GO:0097476 spinal cord motor neuron migration(GO:0097476)
0.1 0.3 GO:1904924 negative regulation of mitophagy in response to mitochondrial depolarization(GO:1904924)
0.1 1.6 GO:0043312 neutrophil degranulation(GO:0043312)
0.1 2.3 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.1 1.0 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.1 0.2 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.1 2.3 GO:0018345 protein palmitoylation(GO:0018345)
0.1 1.3 GO:0048733 sebaceous gland development(GO:0048733)
0.1 0.8 GO:1901250 regulation of lung goblet cell differentiation(GO:1901249) negative regulation of lung goblet cell differentiation(GO:1901250)
0.1 1.2 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.1 5.5 GO:0051693 actin filament capping(GO:0051693)
0.1 0.3 GO:0070278 extracellular matrix constituent secretion(GO:0070278)
0.1 0.4 GO:0097473 cellular response to light intensity(GO:0071484) cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473)
0.1 0.2 GO:0000715 nucleotide-excision repair, DNA damage recognition(GO:0000715)
0.1 0.3 GO:0046501 protoporphyrinogen IX metabolic process(GO:0046501)
0.1 1.6 GO:0007263 nitric oxide mediated signal transduction(GO:0007263)
0.1 0.9 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.1 4.2 GO:0048536 spleen development(GO:0048536)
0.1 0.7 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.1 0.2 GO:1900110 negative regulation of histone H3-K9 dimethylation(GO:1900110)
0.1 0.3 GO:0035092 sperm chromatin condensation(GO:0035092)
0.1 0.4 GO:0090521 glomerular visceral epithelial cell migration(GO:0090521)
0.1 0.4 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.1 0.8 GO:0036006 response to macrophage colony-stimulating factor(GO:0036005) cellular response to macrophage colony-stimulating factor stimulus(GO:0036006)
0.1 2.7 GO:0060216 definitive hemopoiesis(GO:0060216)
0.1 0.3 GO:0031133 regulation of axon diameter(GO:0031133)
0.1 0.3 GO:0034465 response to carbon monoxide(GO:0034465) eye blink reflex(GO:0060082)
0.1 0.8 GO:0045820 negative regulation of glycolytic process(GO:0045820)
0.1 0.3 GO:0072531 pyrimidine-containing compound transmembrane transport(GO:0072531)
0.0 0.4 GO:0060662 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.0 0.4 GO:1900122 positive regulation of receptor binding(GO:1900122)
0.0 7.1 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.9 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.6 GO:0032836 glomerular basement membrane development(GO:0032836)
0.0 0.1 GO:0008292 acetylcholine biosynthetic process(GO:0008292) acetate ester biosynthetic process(GO:1900620)
0.0 0.3 GO:0045218 zonula adherens maintenance(GO:0045218)
0.0 0.1 GO:0090327 negative regulation of locomotion involved in locomotory behavior(GO:0090327)
0.0 2.4 GO:0006414 translational elongation(GO:0006414)
0.0 0.1 GO:0072049 comma-shaped body morphogenesis(GO:0072049)
0.0 0.9 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.7 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.0 0.6 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.0 0.7 GO:0046697 decidualization(GO:0046697)
0.0 0.6 GO:0046512 sphingosine biosynthetic process(GO:0046512)
0.0 0.6 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.0 1.6 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 0.4 GO:0080009 mRNA methylation(GO:0080009)
0.0 0.6 GO:0033962 cytoplasmic mRNA processing body assembly(GO:0033962)
0.0 0.3 GO:0000414 regulation of histone H3-K36 methylation(GO:0000414)
0.0 0.3 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.0 0.4 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 1.3 GO:0051310 metaphase plate congression(GO:0051310)
0.0 0.1 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 0.1 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.0 0.4 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.0 0.3 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.0 1.8 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.2 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.0 0.3 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 4.0 GO:1990830 response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)
0.0 5.1 GO:0007160 cell-matrix adhesion(GO:0007160)
0.0 0.7 GO:0001913 T cell mediated cytotoxicity(GO:0001913)
0.0 1.1 GO:0060612 adipose tissue development(GO:0060612)
0.0 2.7 GO:0050680 negative regulation of epithelial cell proliferation(GO:0050680)
0.0 1.1 GO:0048146 positive regulation of fibroblast proliferation(GO:0048146)
0.0 0.5 GO:0045987 positive regulation of smooth muscle contraction(GO:0045987)
0.0 0.3 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.0 0.3 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.0 0.8 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 1.3 GO:0046579 positive regulation of Ras protein signal transduction(GO:0046579)
0.0 1.1 GO:0015914 phospholipid transport(GO:0015914)
0.0 1.0 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 0.3 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.2 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.0 0.3 GO:0021854 hypothalamus development(GO:0021854)
0.0 1.4 GO:0007052 mitotic spindle organization(GO:0007052)
0.0 0.4 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.0 0.8 GO:0048747 muscle fiber development(GO:0048747)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.5 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.3 0.8 GO:0097144 BAX complex(GO:0097144)
0.3 9.2 GO:0030057 desmosome(GO:0030057)
0.2 3.0 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.2 0.9 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.2 3.0 GO:0090543 Flemming body(GO:0090543)
0.1 0.7 GO:0035189 Rb-E2F complex(GO:0035189)
0.1 1.1 GO:0008091 spectrin(GO:0008091)
0.1 0.9 GO:0031673 H zone(GO:0031673)
0.1 1.7 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 0.4 GO:0060171 stereocilium membrane(GO:0060171)
0.1 2.2 GO:1904115 axon cytoplasm(GO:1904115)
0.1 12.5 GO:0005882 intermediate filament(GO:0005882)
0.1 2.6 GO:0097431 mitotic spindle pole(GO:0097431)
0.1 1.0 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.1 1.2 GO:0000137 Golgi cis cisterna(GO:0000137)
0.1 0.6 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.1 0.8 GO:0044354 pinosome(GO:0044352) macropinosome(GO:0044354)
0.1 0.6 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.1 0.3 GO:0036449 microtubule minus-end(GO:0036449)
0.1 1.1 GO:0043020 NADPH oxidase complex(GO:0043020)
0.1 0.7 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.1 0.4 GO:0036396 MIS complex(GO:0036396)
0.1 0.4 GO:0044611 nuclear pore inner ring(GO:0044611)
0.1 0.4 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.1 1.1 GO:0031143 pseudopodium(GO:0031143)
0.0 0.2 GO:0071942 XPC complex(GO:0071942)
0.0 0.5 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 2.4 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 1.6 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 2.4 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 4.2 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 0.3 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0 0.1 GO:1902737 dendritic filopodium(GO:1902737)
0.0 1.6 GO:0031941 filamentous actin(GO:0031941)
0.0 0.4 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.3 GO:0061700 GATOR2 complex(GO:0061700)
0.0 2.6 GO:0014704 intercalated disc(GO:0014704)
0.0 0.6 GO:0005605 basal lamina(GO:0005605)
0.0 4.4 GO:0031225 anchored component of membrane(GO:0031225)
0.0 8.1 GO:0016324 apical plasma membrane(GO:0016324)
0.0 0.4 GO:0071004 U2-type prespliceosome(GO:0071004)
0.0 1.1 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 1.5 GO:0005902 microvillus(GO:0005902)
0.0 0.7 GO:0008305 integrin complex(GO:0008305)
0.0 0.3 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 1.9 GO:0016363 nuclear matrix(GO:0016363)
0.0 0.6 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.6 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.2 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.1 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.6 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.2 GO:0071564 npBAF complex(GO:0071564)
0.0 0.1 GO:0001739 sex chromatin(GO:0001739)
0.0 0.5 GO:0016235 aggresome(GO:0016235)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 4.2 GO:0004052 arachidonate 12-lipoxygenase activity(GO:0004052)
1.0 5.0 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.7 12.8 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.3 2.0 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.3 2.8 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.3 2.2 GO:0004111 creatine kinase activity(GO:0004111)
0.3 1.0 GO:0030284 estrogen receptor activity(GO:0030284)
0.2 1.7 GO:0034056 estrogen response element binding(GO:0034056)
0.2 3.0 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.2 0.7 GO:0098640 integrin binding involved in cell-matrix adhesion(GO:0098640)
0.2 2.3 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.2 0.8 GO:0070976 calcium-independent protein kinase C activity(GO:0004699) TIR domain binding(GO:0070976)
0.2 3.7 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.2 0.7 GO:0019970 interleukin-11 receptor activity(GO:0004921) interleukin-11 binding(GO:0019970)
0.2 1.5 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.2 0.6 GO:0030629 U6 snRNA 3'-end binding(GO:0030629)
0.2 1.7 GO:0048531 beta-1,3-galactosyltransferase activity(GO:0048531)
0.2 0.9 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.1 3.2 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.1 6.2 GO:0043236 laminin binding(GO:0043236)
0.1 4.5 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1 2.2 GO:0030235 nitric-oxide synthase regulator activity(GO:0030235)
0.1 0.7 GO:0001226 RNA polymerase II transcription corepressor binding(GO:0001226)
0.1 0.5 GO:0048495 Roundabout binding(GO:0048495)
0.1 1.4 GO:0005338 nucleotide-sugar transmembrane transporter activity(GO:0005338)
0.1 5.7 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.1 1.4 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.1 3.2 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.1 1.6 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.1 0.8 GO:0051434 BH3 domain binding(GO:0051434)
0.1 2.0 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 0.5 GO:0004645 phosphorylase activity(GO:0004645)
0.1 1.7 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.1 2.3 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1 0.6 GO:0017040 ceramidase activity(GO:0017040)
0.1 0.2 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1 0.8 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.1 2.7 GO:0071889 14-3-3 protein binding(GO:0071889)
0.1 2.3 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1 0.7 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1 0.4 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.1 0.7 GO:0016505 peptidase activator activity involved in apoptotic process(GO:0016505)
0.0 1.9 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.8 GO:0050897 cobalt ion binding(GO:0050897)
0.0 2.2 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 1.6 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.6 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.3 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.0 0.1 GO:0097677 STAT family protein binding(GO:0097677)
0.0 0.1 GO:0035939 microsatellite binding(GO:0035939)
0.0 0.3 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0 0.8 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 2.7 GO:0070888 E-box binding(GO:0070888)
0.0 0.7 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 0.3 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 1.4 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.9 GO:0070410 JUN kinase binding(GO:0008432) co-SMAD binding(GO:0070410)
0.0 1.6 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 1.1 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.3 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.4 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0 0.5 GO:0005522 profilin binding(GO:0005522)
0.0 0.4 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.9 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.3 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.3 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.5 GO:0042166 acetylcholine binding(GO:0042166)
0.0 2.4 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.0 0.2 GO:0001164 RNA polymerase I regulatory region DNA binding(GO:0001013) RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.0 0.4 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.3 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.0 5.3 GO:0042393 histone binding(GO:0042393)
0.0 3.0 GO:0043492 ATPase activity, coupled to transmembrane movement of substances(GO:0042626) ATPase activity, coupled to movement of substances(GO:0043492)
0.0 1.3 GO:0019894 kinesin binding(GO:0019894)
0.0 0.9 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.1 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.0 0.3 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)
0.0 0.8 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.9 GO:0033613 activating transcription factor binding(GO:0033613)
0.0 0.9 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 1.0 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.6 GO:0005109 frizzled binding(GO:0005109)
0.0 0.1 GO:0031849 olfactory receptor binding(GO:0031849)
0.0 0.3 GO:0015215 nucleotide transmembrane transporter activity(GO:0015215)
0.0 0.4 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.3 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 1.4 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.7 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 10.3 GO:0005198 structural molecule activity(GO:0005198)
0.0 0.4 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 0.4 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 0.1 GO:0030619 U1 snRNA binding(GO:0030619)
0.0 0.3 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.0 6.8 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 2.6 GO:0003713 transcription coactivator activity(GO:0003713)
0.0 0.8 GO:0005080 protein kinase C binding(GO:0005080)
0.0 7.7 GO:0005509 calcium ion binding(GO:0005509)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.0 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 2.0 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.1 3.7 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.1 0.2 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.1 3.1 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.1 0.8 PID IL5 PATHWAY IL5-mediated signaling events
0.1 4.4 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.1 3.6 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.1 0.9 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 2.2 PID RAS PATHWAY Regulation of Ras family activation
0.1 2.9 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 3.8 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 4.5 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 1.6 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 3.6 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 2.2 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 2.6 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.6 PID IL3 PATHWAY IL3-mediated signaling events
0.0 3.5 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 1.8 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 2.6 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 0.9 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 1.0 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 1.5 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 1.0 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.3 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.3 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.9 PID BMP PATHWAY BMP receptor signaling
0.0 1.3 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.8 PID CDC42 PATHWAY CDC42 signaling events
0.0 0.5 PID MTOR 4PATHWAY mTOR signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.6 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.2 3.0 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.1 3.0 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.1 2.0 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 3.4 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.1 3.6 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.1 3.4 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.1 2.0 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.1 1.4 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.1 11.8 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.1 1.3 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.1 0.8 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 1.5 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 4.7 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 4.8 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.4 REACTOME PROLONGED ERK ACTIVATION EVENTS Genes involved in Prolonged ERK activation events
0.0 0.5 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 2.7 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 1.5 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 1.1 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 1.2 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.6 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.8 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 0.1 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 1.1 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 1.1 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 1.1 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 1.8 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.5 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 0.6 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.7 REACTOME DAG AND IP3 SIGNALING Genes involved in DAG and IP3 signaling
0.0 0.5 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.0 0.3 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.6 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 1.0 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.7 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.4 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery