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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Tfap2c

Z-value: 1.07

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Transcription factors associated with Tfap2c

Gene Symbol Gene ID Gene Info
Tfap2c
ENSMUSG00000028640.12 Tfap2c

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Tfap2cmm39_v1_chr2_+_172392678_1723927020.094.4e-01Click!

Activity profile of Tfap2c motif

Sorted Z-values of Tfap2c motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Tfap2c

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr19_+_10366753 9.83 ENSMUST00000169121.9
ENSMUST00000076968.11
ENSMUST00000235479.2
ENSMUST00000223586.2
ENSMUST00000235784.2
ENSMUST00000224135.3
ENSMUST00000225452.3
ENSMUST00000237366.2
Syt7
synaptotagmin VII
chr5_+_24679154 6.05 ENSMUST00000199856.2
Agap3
ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
chr9_+_89791943 5.84 ENSMUST00000189545.2
ENSMUST00000034909.11
ENSMUST00000034912.6
Rasgrf1
RAS protein-specific guanine nucleotide-releasing factor 1
chr6_-_42670021 5.78 ENSMUST00000121083.8
Tcaf1
TRPM8 channel-associated factor 1
chr6_-_42669963 5.67 ENSMUST00000045140.5
Tcaf1
TRPM8 channel-associated factor 1
chr7_-_45019984 5.63 ENSMUST00000003971.10
Lin7b
lin-7 homolog B (C. elegans)
chr9_-_121323906 5.61 ENSMUST00000215228.2
ENSMUST00000213106.2
Cck
cholecystokinin
chr1_-_75240551 5.46 ENSMUST00000186178.7
ENSMUST00000189769.7
ENSMUST00000027404.12
Ptprn
protein tyrosine phosphatase, receptor type, N
chr2_+_156263002 5.34 ENSMUST00000125153.10
ENSMUST00000103136.8
ENSMUST00000109577.9
Epb41l1
erythrocyte membrane protein band 4.1 like 1
chr9_+_58395850 5.23 ENSMUST00000085658.5
Insyn1
inhibitory synaptic factor 1
chr11_-_119907884 5.22 ENSMUST00000132575.8
Aatk
apoptosis-associated tyrosine kinase
chr6_+_118043307 5.14 ENSMUST00000203804.3
ENSMUST00000203482.2
Rasgef1a
RasGEF domain family, member 1A
chr7_-_100543891 5.07 ENSMUST00000209041.2
Arhgef17
Rho guanine nucleotide exchange factor (GEF) 17
chr11_-_65053710 5.03 ENSMUST00000093002.12
ENSMUST00000047463.15
Arhgap44
Rho GTPase activating protein 44
chr11_-_94364914 4.99 ENSMUST00000107786.8
ENSMUST00000107791.8
ENSMUST00000103166.9
ENSMUST00000107792.8
ENSMUST00000100561.10
ENSMUST00000107793.8
ENSMUST00000107788.8
ENSMUST00000107790.8
ENSMUST00000107789.8
ENSMUST00000107785.2
ENSMUST00000021234.15
Cacna1g
calcium channel, voltage-dependent, T type, alpha 1G subunit
chr14_+_7030760 4.82 ENSMUST00000055211.6
Lrrc3b
leucine rich repeat containing 3B
chrX_-_132589727 4.78 ENSMUST00000149154.8
Pcdh19
protocadherin 19
chr11_+_67345895 4.77 ENSMUST00000108681.9
Gas7
growth arrest specific 7
chr6_+_38639945 4.74 ENSMUST00000114874.5
Clec2l
C-type lectin domain family 2, member L
chr9_-_121825028 4.73 ENSMUST00000216669.2
ENSMUST00000215084.2
ENSMUST00000214533.2
ENSMUST00000217610.2
ENSMUST00000084743.7
Pomgnt2
protein O-linked mannose beta 1,4-N-acetylglucosaminyltransferase 2
chr5_-_24806960 4.64 ENSMUST00000030791.12
Smarcd3
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
chr6_+_88175312 4.59 ENSMUST00000203480.2
ENSMUST00000015197.9
Gata2
GATA binding protein 2
chr9_-_20657643 4.52 ENSMUST00000215999.2
Olfm2
olfactomedin 2
chrX_+_52609954 4.51 ENSMUST00000063384.4
Rtl8c
retrotransposon Gag like 8C
chr2_-_32243295 4.50 ENSMUST00000091089.12
ENSMUST00000078352.12
ENSMUST00000113350.8
ENSMUST00000202578.4
ENSMUST00000113365.8
Dnm1
dynamin 1
chr1_+_75456173 4.48 ENSMUST00000113575.9
ENSMUST00000148980.2
ENSMUST00000050899.7
ENSMUST00000187411.2
Tmem198
transmembrane protein 198
chr5_-_71253107 4.48 ENSMUST00000197284.5
Gabra2
gamma-aminobutyric acid (GABA) A receptor, subunit alpha 2
chr6_-_28831746 4.37 ENSMUST00000062304.7
Lrrc4
leucine rich repeat containing 4
chr4_-_56990306 4.31 ENSMUST00000053681.6
Frrs1l
ferric-chelate reductase 1 like
chr9_-_29323032 4.25 ENSMUST00000115236.2
Ntm
neurotrimin
chr2_+_35512172 4.17 ENSMUST00000112992.9
Dab2ip
disabled 2 interacting protein
chr2_+_156262957 4.10 ENSMUST00000109574.8
Epb41l1
erythrocyte membrane protein band 4.1 like 1
chr9_+_121589044 4.10 ENSMUST00000093772.4
Zfp651
zinc finger protein 651
chr2_-_170269748 4.03 ENSMUST00000013667.3
ENSMUST00000109152.9
ENSMUST00000068137.11
Bcas1
breast carcinoma amplified sequence 1
chr18_+_86413077 4.02 ENSMUST00000058829.4
Neto1
neuropilin (NRP) and tolloid (TLL)-like 1
chr11_-_59855762 3.93 ENSMUST00000062405.8
Rasd1
RAS, dexamethasone-induced 1
chr9_+_109760856 3.91 ENSMUST00000169851.8
Map4
microtubule-associated protein 4
chr14_-_65499835 3.86 ENSMUST00000131309.3
Fzd3
frizzled class receptor 3
chr2_+_32498997 3.84 ENSMUST00000143625.2
ENSMUST00000128811.2
St6galnac6
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
chr9_-_29323500 3.77 ENSMUST00000115237.8
Ntm
neurotrimin
chr12_-_81379903 3.75 ENSMUST00000085238.13
ENSMUST00000182208.8
Slc8a3
solute carrier family 8 (sodium/calcium exchanger), member 3
chr1_-_84912810 3.74 ENSMUST00000027422.7
Slc16a14
solute carrier family 16 (monocarboxylic acid transporters), member 14
chr13_+_54519161 3.72 ENSMUST00000026985.9
Cplx2
complexin 2
chr14_+_121272606 3.67 ENSMUST00000135010.8
Farp1
FERM, RhoGEF (Arhgef) and pleckstrin domain protein 1 (chondrocyte-derived)
chr19_+_10366450 3.67 ENSMUST00000073899.6
Syt7
synaptotagmin VII
chr7_-_138768374 3.66 ENSMUST00000016125.12
Stk32c
serine/threonine kinase 32C
chr2_+_156262756 3.65 ENSMUST00000103137.10
Epb41l1
erythrocyte membrane protein band 4.1 like 1
chr11_-_101875575 3.49 ENSMUST00000176261.2
ENSMUST00000143177.2
ENSMUST00000003612.13
Dusp3
dual specificity phosphatase 3 (vaccinia virus phosphatase VH1-related)
chr2_-_32243246 3.40 ENSMUST00000201433.4
ENSMUST00000113352.9
ENSMUST00000201494.4
Dnm1
dynamin 1
chr2_+_35512023 3.38 ENSMUST00000091010.12
Dab2ip
disabled 2 interacting protein
chr2_-_32271921 3.34 ENSMUST00000048792.5
1110008P14Rik
RIKEN cDNA 1110008P14 gene
chr15_+_87509413 3.29 ENSMUST00000068088.8
Tafa5
TAFA chemokine like family member 5
chr2_+_138098454 3.27 ENSMUST00000091556.12
Btbd3
BTB (POZ) domain containing 3
chr4_+_124779592 3.19 ENSMUST00000149146.2
Epha10
Eph receptor A10
chr7_+_131568167 3.16 ENSMUST00000045840.5
Gpr26
G protein-coupled receptor 26
chrX_+_162691978 3.09 ENSMUST00000069041.15
Ap1s2
adaptor-related protein complex 1, sigma 2 subunit
chr1_-_75455915 3.05 ENSMUST00000079205.14
ENSMUST00000094818.4
Chpf
chondroitin polymerizing factor
chr4_-_148244299 3.01 ENSMUST00000151127.8
ENSMUST00000105705.9
Fbxo44
F-box protein 44
chrX_-_141089165 3.00 ENSMUST00000134825.3
Kcne1l
potassium voltage-gated channel, Isk-related family, member 1-like, pseudogene
chr4_+_138181616 2.88 ENSMUST00000050918.4
Camk2n1
calcium/calmodulin-dependent protein kinase II inhibitor 1
chr12_+_111725357 2.88 ENSMUST00000118471.8
ENSMUST00000122300.8
Klc1
kinesin light chain 1
chr9_-_21963306 2.85 ENSMUST00000003501.9
ENSMUST00000215901.2
Elavl3
ELAV like RNA binding protein 3
chr10_-_29411857 2.78 ENSMUST00000092623.5
Rspo3
R-spondin 3
chr15_+_54434576 2.76 ENSMUST00000025356.4
Mal2
mal, T cell differentiation protein 2
chr7_-_109559671 2.74 ENSMUST00000080437.13
Dennd5a
DENN/MADD domain containing 5A
chrX_-_72868544 2.70 ENSMUST00000002080.12
ENSMUST00000114438.3
Pdzd4
PDZ domain containing 4
chr15_-_89033761 2.69 ENSMUST00000088823.5
Mapk11
mitogen-activated protein kinase 11
chr8_+_26008799 2.62 ENSMUST00000119398.10
ENSMUST00000117179.9
Fgfr1
fibroblast growth factor receptor 1
chr12_+_111725282 2.61 ENSMUST00000239017.2
ENSMUST00000084941.12
Klc1
kinesin light chain 1
chr4_+_104224774 2.60 ENSMUST00000106830.9
Dab1
disabled 1
chr11_-_28534260 2.57 ENSMUST00000093253.10
ENSMUST00000109502.9
ENSMUST00000042534.15
Ccdc85a
coiled-coil domain containing 85A
chr11_-_119937896 2.56 ENSMUST00000064307.10
Aatk
apoptosis-associated tyrosine kinase
chr5_+_144482693 2.56 ENSMUST00000071782.8
Nptx2
neuronal pentraxin 2
chr3_-_88997261 2.54 ENSMUST00000196223.5
ENSMUST00000196043.2
ENSMUST00000166687.6
Rusc1
RUN and SH3 domain containing 1
chr14_-_20844034 2.53 ENSMUST00000226630.2
Camk2g
calcium/calmodulin-dependent protein kinase II gamma
chrX_-_20787150 2.50 ENSMUST00000081893.7
ENSMUST00000115345.8
Syn1
synapsin I
chr11_-_33942981 2.49 ENSMUST00000238903.2
Kcnip1
Kv channel-interacting protein 1
chr17_-_56783376 2.45 ENSMUST00000223859.2
Ptprs
protein tyrosine phosphatase, receptor type, S
chr7_-_109559593 2.44 ENSMUST00000106722.2
Dennd5a
DENN/MADD domain containing 5A
chr8_+_26008773 2.41 ENSMUST00000084027.13
ENSMUST00000178276.8
ENSMUST00000179592.8
Fgfr1
fibroblast growth factor receptor 1
chr10_+_24099415 2.40 ENSMUST00000095784.3
Moxd1
monooxygenase, DBH-like 1
chr18_-_33596468 2.40 ENSMUST00000171533.9
Nrep
neuronal regeneration related protein
chr1_+_181180183 2.40 ENSMUST00000161880.8
ENSMUST00000027795.14
Cnih3
cornichon family AMPA receptor auxiliary protein 3
chr7_-_140773859 2.38 ENSMUST00000026572.11
ENSMUST00000168550.8
ENSMUST00000097957.11
Hras
Harvey rat sarcoma virus oncogene
chr19_-_6964988 2.37 ENSMUST00000130048.8
ENSMUST00000025914.7
Vegfb
vascular endothelial growth factor B
chr9_-_107109108 2.36 ENSMUST00000044532.11
Dock3
dedicator of cyto-kinesis 3
chr4_+_48585135 2.36 ENSMUST00000030032.13
Tmeff1
transmembrane protein with EGF-like and two follistatin-like domains 1
chr2_+_174169539 2.33 ENSMUST00000133356.8
ENSMUST00000087871.11
Gnas
GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus
chr17_-_56783462 2.32 ENSMUST00000067538.6
Ptprs
protein tyrosine phosphatase, receptor type, S
chr2_+_35146390 2.31 ENSMUST00000201185.4
ENSMUST00000202990.4
ENSMUST00000202899.4
ENSMUST00000142324.8
ENSMUST00000139867.5
Gsn
gelsolin
chr4_+_125384481 2.30 ENSMUST00000030676.8
Grik3
glutamate receptor, ionotropic, kainate 3
chr14_+_121272950 2.30 ENSMUST00000026635.8
Farp1
FERM, RhoGEF (Arhgef) and pleckstrin domain protein 1 (chondrocyte-derived)
chr11_+_98274637 2.29 ENSMUST00000008021.3
Tcap
titin-cap
chr17_+_37357451 2.28 ENSMUST00000172789.2
Gabbr1
gamma-aminobutyric acid (GABA) B receptor, 1
chr4_+_152423075 2.27 ENSMUST00000030775.12
ENSMUST00000164662.8
Chd5
chromodomain helicase DNA binding protein 5
chr2_+_174169351 2.26 ENSMUST00000124935.8
Gnas
GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus
chr4_+_48585275 2.23 ENSMUST00000123476.8
Tmeff1
transmembrane protein with EGF-like and two follistatin-like domains 1
chr2_-_165076609 2.22 ENSMUST00000065438.13
Cdh22
cadherin 22
chr2_-_32271833 2.22 ENSMUST00000146423.2
1110008P14Rik
RIKEN cDNA 1110008P14 gene
chr7_-_19338349 2.21 ENSMUST00000086041.7
Clasrp
CLK4-associating serine/arginine rich protein
chrX_-_100128958 2.20 ENSMUST00000101362.8
ENSMUST00000073927.5
Slc7a3
solute carrier family 7 (cationic amino acid transporter, y+ system), member 3
chr6_+_4504814 2.20 ENSMUST00000141483.8
Col1a2
collagen, type I, alpha 2
chr14_+_119375753 2.19 ENSMUST00000065904.5
Hs6st3
heparan sulfate 6-O-sulfotransferase 3
chrX_-_47123719 2.19 ENSMUST00000039026.8
Apln
apelin
chr16_+_91022300 2.16 ENSMUST00000035608.10
Olig2
oligodendrocyte transcription factor 2
chrX_+_162692126 2.12 ENSMUST00000033734.14
ENSMUST00000112294.9
Ap1s2
adaptor-related protein complex 1, sigma 2 subunit
chr11_+_102080489 2.11 ENSMUST00000078975.8
G6pc3
glucose 6 phosphatase, catalytic, 3
chr2_+_174169492 2.09 ENSMUST00000156623.8
ENSMUST00000149016.9
Gnas
GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus
chr18_-_61147272 2.02 ENSMUST00000025520.10
Slc6a7
solute carrier family 6 (neurotransmitter transporter, L-proline), member 7
chr11_-_80268800 2.01 ENSMUST00000179332.8
ENSMUST00000103225.11
ENSMUST00000134274.2
5730455P16Rik
RIKEN cDNA 5730455P16 gene
chr19_+_5118103 2.01 ENSMUST00000070630.8
Cd248
CD248 antigen, endosialin
chr19_+_10019023 2.00 ENSMUST00000237672.2
Fads3
fatty acid desaturase 3
chr4_+_152423344 1.98 ENSMUST00000005175.5
Chd5
chromodomain helicase DNA binding protein 5
chr3_-_154302679 1.97 ENSMUST00000052774.8
ENSMUST00000170461.8
ENSMUST00000122976.2
Tyw3
tRNA-yW synthesizing protein 3 homolog (S. cerevisiae)
chr10_-_75396164 1.97 ENSMUST00000051129.10
Lrrc75b
leucine rich repeat containing 75B
chr12_-_65120674 1.95 ENSMUST00000220983.2
ENSMUST00000220730.2
ENSMUST00000021332.10
Fkbp3
FK506 binding protein 3
chr2_+_139520098 1.93 ENSMUST00000184404.8
ENSMUST00000099307.4
Ism1
isthmin 1, angiogenesis inhibitor
chr4_-_96029375 1.92 ENSMUST00000097972.5
Cyp2j12
cytochrome P450, family 2, subfamily j, polypeptide 12
chr7_-_43139390 1.88 ENSMUST00000107974.3
Iglon5
IgLON family member 5
chrX_+_71006170 1.87 ENSMUST00000126362.8
ENSMUST00000170096.8
Prrg3
proline rich Gla (G-carboxyglutamic acid) 3 (transmembrane)
chr17_-_16050913 1.86 ENSMUST00000231281.2
Rgmb
repulsive guidance molecule family member B
chr12_-_76756772 1.86 ENSMUST00000166101.2
Sptb
spectrin beta, erythrocytic
chr18_-_62044871 1.82 ENSMUST00000166783.3
ENSMUST00000049378.15
Ablim3
actin binding LIM protein family, member 3
chr14_+_120715855 1.82 ENSMUST00000062117.14
Rap2a
RAS related protein 2a
chr5_-_35836761 1.81 ENSMUST00000114233.3
Htra3
HtrA serine peptidase 3
chr17_+_86475205 1.80 ENSMUST00000097275.9
Prkce
protein kinase C, epsilon
chr11_+_102080446 1.79 ENSMUST00000070334.10
G6pc3
glucose 6 phosphatase, catalytic, 3
chr4_+_45203914 1.79 ENSMUST00000107804.2
Frmpd1
FERM and PDZ domain containing 1
chr11_+_70431063 1.79 ENSMUST00000018429.12
ENSMUST00000108557.10
ENSMUST00000108556.2
Pld2
phospholipase D2
chr2_+_135501605 1.75 ENSMUST00000134310.8
Plcb4
phospholipase C, beta 4
chr17_-_30107544 1.72 ENSMUST00000171691.9
Mdga1
MAM domain containing glycosylphosphatidylinositol anchor 1
chr6_-_32565127 1.68 ENSMUST00000115096.4
Plxna4
plexin A4
chrX_+_133657312 1.67 ENSMUST00000081834.10
ENSMUST00000086880.11
ENSMUST00000086884.5
Armcx3
armadillo repeat containing, X-linked 3
chr18_-_33596890 1.64 ENSMUST00000237066.2
Nrep
neuronal regeneration related protein
chr4_+_40473130 1.63 ENSMUST00000179526.2
Tmem215
transmembrane protein 215
chr17_-_66756710 1.62 ENSMUST00000086693.12
ENSMUST00000097291.10
Mtcl1
microtubule crosslinking factor 1
chr10_-_13744523 1.62 ENSMUST00000105534.10
Aig1
androgen-induced 1
chr3_+_154302989 1.60 ENSMUST00000140644.8
ENSMUST00000144764.8
ENSMUST00000155232.2
Cryz
crystallin, zeta
chr7_-_16550656 1.60 ENSMUST00000061390.9
Fkrp
fukutin related protein
chr19_+_59446804 1.58 ENSMUST00000062216.4
Emx2
empty spiracles homeobox 2
chr4_+_131649001 1.57 ENSMUST00000094666.4
Tmem200b
transmembrane protein 200B
chr9_-_42035560 1.56 ENSMUST00000060989.9
Sorl1
sortilin-related receptor, LDLR class A repeats-containing
chr9_+_108174052 1.54 ENSMUST00000035230.7
Amt
aminomethyltransferase
chr8_-_37081091 1.53 ENSMUST00000033923.14
Dlc1
deleted in liver cancer 1
chr6_+_40302106 1.53 ENSMUST00000031977.12
Agk
acylglycerol kinase
chr10_-_121146940 1.52 ENSMUST00000064107.7
Tbc1d30
TBC1 domain family, member 30
chr9_+_74944994 1.51 ENSMUST00000007800.8
Arpp19
cAMP-regulated phosphoprotein 19
chr11_-_58346806 1.50 ENSMUST00000055204.6
Olfr30
olfactory receptor 30
chr10_-_13744676 1.50 ENSMUST00000019942.6
ENSMUST00000162610.8
Aig1
androgen-induced 1
chr7_-_138447933 1.50 ENSMUST00000118810.2
ENSMUST00000075667.5
ENSMUST00000119664.2
Mapk1ip1
mitogen-activated protein kinase 1 interacting protein 1
chr11_-_97590460 1.49 ENSMUST00000103148.8
ENSMUST00000169807.8
Pcgf2
polycomb group ring finger 2
chr4_-_148021159 1.48 ENSMUST00000105712.2
Plod1
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1
chr11_+_77384234 1.46 ENSMUST00000037285.10
ENSMUST00000100812.4
Git1
GIT ArfGAP 1
chr5_-_114582053 1.45 ENSMUST00000123256.3
ENSMUST00000112245.6
Mmab
methylmalonic aciduria (cobalamin deficiency) cblB type homolog (human)
chr4_-_148021217 1.44 ENSMUST00000019199.14
Plod1
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1
chr2_+_103788321 1.44 ENSMUST00000156813.8
ENSMUST00000170926.8
Lmo2
LIM domain only 2
chr7_+_6289572 1.44 ENSMUST00000086327.12
ENSMUST00000153840.2
ENSMUST00000170776.8
Zfp667
zinc finger protein 667
chr6_-_12749192 1.42 ENSMUST00000172356.8
Thsd7a
thrombospondin, type I, domain containing 7A
chr6_-_97037366 1.41 ENSMUST00000089295.6
Tafa4
TAFA chemokine like family member 4
chr11_-_76737794 1.41 ENSMUST00000021201.6
Cpd
carboxypeptidase D
chr11_-_66416621 1.38 ENSMUST00000123454.8
Shisa6
shisa family member 6
chr8_+_84699580 1.36 ENSMUST00000005606.8
Prkaca
protein kinase, cAMP dependent, catalytic, alpha
chr9_+_45341589 1.34 ENSMUST00000239471.2
ENSMUST00000034592.11
ENSMUST00000239429.2
Dscaml1
DS cell adhesion molecule like 1
chrX_+_128650486 1.33 ENSMUST00000167619.9
ENSMUST00000037854.15
Diaph2
diaphanous related formin 2
chrX_+_71006577 1.31 ENSMUST00000048790.7
Prrg3
proline rich Gla (G-carboxyglutamic acid) 3 (transmembrane)
chr11_+_78389913 1.30 ENSMUST00000017488.5
Vtn
vitronectin
chr9_-_105705321 1.29 ENSMUST00000098441.10
Col6a6
collagen, type VI, alpha 6
chr3_+_154302777 1.27 ENSMUST00000194876.6
Cryz
crystallin, zeta
chr4_-_116321348 1.25 ENSMUST00000106486.8
ENSMUST00000106485.8
Mast2
microtubule associated serine/threonine kinase 2
chr17_-_46867083 1.22 ENSMUST00000015749.7
Srf
serum response factor
chr3_+_154302311 1.22 ENSMUST00000192462.6
ENSMUST00000029850.15
Cryz
crystallin, zeta
chr2_+_81883566 1.21 ENSMUST00000047527.8
Zfp804a
zinc finger protein 804A
chr6_+_22288220 1.21 ENSMUST00000128245.8
ENSMUST00000031681.10
ENSMUST00000148639.2
Wnt16
wingless-type MMTV integration site family, member 16
chr15_+_80171435 1.21 ENSMUST00000160424.8
Cacna1i
calcium channel, voltage-dependent, alpha 1I subunit
chr18_+_65020910 1.18 ENSMUST00000236736.2
ENSMUST00000235743.2
Nedd4l
neural precursor cell expressed, developmentally down-regulated gene 4-like
chr18_-_33597060 1.17 ENSMUST00000168890.2
Nrep
neuronal regeneration related protein
chr2_+_29759495 1.16 ENSMUST00000047521.7
ENSMUST00000134152.2
Cercam
cerebral endothelial cell adhesion molecule
chr3_-_107993906 1.16 ENSMUST00000102638.8
ENSMUST00000102637.8
Ampd2
adenosine monophosphate deaminase 2
chr9_+_109760931 1.15 ENSMUST00000165876.8
Map4
microtubule-associated protein 4
chr7_+_16186704 1.14 ENSMUST00000019302.10
Tmem160
transmembrane protein 160
chr18_-_33596792 1.13 ENSMUST00000051087.16
Nrep
neuronal regeneration related protein
chr3_-_148696155 1.12 ENSMUST00000196526.5
ENSMUST00000200543.5
ENSMUST00000200154.5
Adgrl2
adhesion G protein-coupled receptor L2
chr19_+_10018914 1.11 ENSMUST00000115995.4
Fads3
fatty acid desaturase 3
chr9_+_109760528 1.10 ENSMUST00000035055.15
Map4
microtubule-associated protein 4
chr5_-_114582097 1.10 ENSMUST00000031560.14
Mmab
methylmalonic aciduria (cobalamin deficiency) cblB type homolog (human)
chr17_-_16051295 1.08 ENSMUST00000231985.2
Rgmb
repulsive guidance molecule family member B
chr4_+_105014536 1.07 ENSMUST00000064139.8
Plpp3
phospholipid phosphatase 3
chr7_+_65511482 1.05 ENSMUST00000176199.8
Pcsk6
proprotein convertase subtilisin/kexin type 6
chr7_+_3697511 1.05 ENSMUST00000108627.4
Tsen34
tRNA splicing endonuclease subunit 34
chr4_-_117146624 1.04 ENSMUST00000221654.2
Rnf220
ring finger protein 220
chr5_-_92582969 1.04 ENSMUST00000135112.8
Nup54
nucleoporin 54
chr5_+_137756407 1.03 ENSMUST00000141733.8
ENSMUST00000110985.2
Tsc22d4
TSC22 domain family, member 4
chr18_+_65020760 1.01 ENSMUST00000235343.2
Nedd4l
neural precursor cell expressed, developmentally down-regulated gene 4-like
chr11_+_70430870 1.00 ENSMUST00000157075.8
Pld2
phospholipase D2
chr10_-_127177729 0.99 ENSMUST00000026474.5
ENSMUST00000219671.2
Gli1
GLI-Kruppel family member GLI1
chr11_+_85243970 0.99 ENSMUST00000108056.8
ENSMUST00000108061.8
ENSMUST00000108062.8
ENSMUST00000138423.8
ENSMUST00000092821.10
ENSMUST00000074875.11
Bcas3
breast carcinoma amplified sequence 3
chr13_-_72111832 0.98 ENSMUST00000077337.9
Irx1
Iroquois homeobox 1
chr9_+_74945021 0.96 ENSMUST00000168301.2
Arpp19
cAMP-regulated phosphoprotein 19
chr8_-_65302573 0.96 ENSMUST00000210166.2
Klhl2
kelch-like 2, Mayven
chr9_-_39918243 0.96 ENSMUST00000073932.4
Olfr980
olfactory receptor 980

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
4.5 13.5 GO:1990926 short-term synaptic potentiation(GO:1990926)
1.7 5.0 GO:0021837 motogenic signaling involved in postnatal olfactory bulb interneuron migration(GO:0021837) positive regulation of mitotic cell cycle DNA replication(GO:1903465)
1.5 7.5 GO:0036324 vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324)
1.4 11.5 GO:1901529 positive regulation of anion channel activity(GO:1901529)
1.3 7.9 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
1.1 4.6 GO:0035854 eosinophil fate commitment(GO:0035854)
1.1 5.5 GO:0035617 stress granule disassembly(GO:0035617)
1.1 5.4 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
1.0 5.0 GO:0098886 modification of dendritic spine(GO:0098886)
1.0 4.0 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
1.0 3.9 GO:0045976 negative regulation of mitotic cell cycle, embryonic(GO:0045976)
1.0 4.8 GO:0034164 negative regulation of toll-like receptor 9 signaling pathway(GO:0034164)
0.9 5.6 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.9 6.2 GO:0051012 microtubule sliding(GO:0051012)
0.9 2.6 GO:0021589 hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589)
0.8 2.4 GO:0006589 octopamine biosynthetic process(GO:0006589) octopamine metabolic process(GO:0046333)
0.7 6.7 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.7 2.2 GO:1904020 regulation of G-protein coupled receptor internalization(GO:1904020)
0.7 2.2 GO:0021530 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.7 4.6 GO:0003219 cardiac right ventricle formation(GO:0003219)
0.6 7.8 GO:0032482 Rab protein signal transduction(GO:0032482)
0.6 2.9 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.6 1.7 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.6 2.3 GO:1902174 renal protein absorption(GO:0097017) protein processing in phagocytic vesicle(GO:1900756) positive regulation of keratinocyte apoptotic process(GO:1902174) regulation of protein processing in phagocytic vesicle(GO:1903921) positive regulation of protein processing in phagocytic vesicle(GO:1903923)
0.6 6.1 GO:0030578 PML body organization(GO:0030578)
0.5 2.7 GO:0072086 specification of loop of Henle identity(GO:0072086)
0.5 1.6 GO:0021644 vagus nerve morphogenesis(GO:0021644)
0.5 3.7 GO:1990034 calcium ion export from cell(GO:1990034)
0.5 4.3 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.5 6.3 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.5 2.0 GO:0035524 proline transmembrane transport(GO:0035524)
0.5 2.4 GO:0035470 positive regulation of vascular wound healing(GO:0035470)
0.4 2.5 GO:0009235 cobalamin metabolic process(GO:0009235)
0.4 1.6 GO:2001137 protein retention in Golgi apparatus(GO:0045053) positive regulation of endocytic recycling(GO:2001137)
0.4 3.9 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.4 5.6 GO:0051901 positive regulation of mitochondrial depolarization(GO:0051901)
0.4 2.2 GO:0015819 lysine transport(GO:0015819)
0.4 2.2 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.4 1.8 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.3 2.8 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.3 2.7 GO:2001184 positive regulation of interleukin-12 secretion(GO:2001184)
0.3 1.0 GO:0060032 notochord regression(GO:0060032)
0.3 2.3 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
0.3 2.3 GO:0014053 negative regulation of gamma-aminobutyric acid secretion(GO:0014053)
0.3 1.9 GO:0032902 nerve growth factor production(GO:0032902)
0.3 5.5 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.3 0.9 GO:0003273 cell migration involved in endocardial cushion formation(GO:0003273)
0.3 1.2 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.3 4.5 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.3 2.4 GO:2000630 positive regulation of miRNA metabolic process(GO:2000630)
0.3 3.8 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.3 1.9 GO:0019254 carnitine metabolic process, CoA-linked(GO:0019254)
0.3 5.8 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.3 1.0 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.3 2.3 GO:0060372 regulation of atrial cardiac muscle cell membrane repolarization(GO:0060372)
0.2 1.2 GO:0090403 oxidative stress-induced premature senescence(GO:0090403)
0.2 13.3 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.2 3.5 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
0.2 3.0 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.2 1.4 GO:0071374 cellular response to parathyroid hormone stimulus(GO:0071374)
0.2 2.2 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.2 0.9 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.2 2.9 GO:0043589 skin morphogenesis(GO:0043589)
0.2 0.9 GO:0035521 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.2 4.4 GO:0097119 postsynaptic density protein 95 clustering(GO:0097119)
0.2 1.7 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.2 1.1 GO:0044330 canonical Wnt signaling pathway involved in positive regulation of wound healing(GO:0044330)
0.2 1.1 GO:0097309 cap1 mRNA methylation(GO:0097309)
0.2 4.9 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.2 0.8 GO:0018197 peptidyl-aspartic acid modification(GO:0018197)
0.2 0.8 GO:0036091 positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
0.2 3.4 GO:1901897 regulation of relaxation of cardiac muscle(GO:1901897)
0.2 0.8 GO:0072385 minus-end-directed organelle transport along microtubule(GO:0072385)
0.2 0.9 GO:1902167 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902167)
0.2 2.3 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.2 2.8 GO:0002031 G-protein coupled receptor internalization(GO:0002031)
0.2 4.3 GO:0042178 xenobiotic catabolic process(GO:0042178)
0.2 1.7 GO:0051964 negative regulation of synapse assembly(GO:0051964)
0.2 1.5 GO:1902018 negative regulation of cilium assembly(GO:1902018)
0.1 1.9 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.1 3.2 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.1 1.4 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.1 0.4 GO:1900106 hyaluranon cable assembly(GO:0036118) nephrogenic mesenchyme development(GO:0072076) kidney mesenchyme morphogenesis(GO:0072131) metanephric mesenchyme morphogenesis(GO:0072133) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.1 3.9 GO:0007263 nitric oxide mediated signal transduction(GO:0007263)
0.1 0.6 GO:0036228 protein targeting to nuclear inner membrane(GO:0036228)
0.1 2.8 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.1 1.6 GO:2000576 positive regulation of microtubule motor activity(GO:2000576)
0.1 0.5 GO:1902303 negative regulation of potassium ion export(GO:1902303)
0.1 1.3 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.1 0.2 GO:0010909 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909)
0.1 6.7 GO:1900449 regulation of glutamate receptor signaling pathway(GO:1900449)
0.1 2.0 GO:0060033 anatomical structure regression(GO:0060033)
0.1 1.2 GO:0032264 IMP salvage(GO:0032264)
0.1 1.3 GO:0045075 interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
0.1 4.5 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.1 0.3 GO:0002017 regulation of blood volume by renal aldosterone(GO:0002017)
0.1 1.0 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.1 2.5 GO:0045760 positive regulation of action potential(GO:0045760)
0.1 2.2 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.1 1.6 GO:0043267 negative regulation of potassium ion transport(GO:0043267)
0.1 1.5 GO:0001771 immunological synapse formation(GO:0001771)
0.1 1.5 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.1 5.1 GO:0060612 adipose tissue development(GO:0060612)
0.1 2.5 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.1 1.8 GO:0030033 microvillus assembly(GO:0030033)
0.1 0.5 GO:1903026 negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
0.1 1.6 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.1 0.2 GO:1902164 positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.1 0.4 GO:0045077 negative regulation of interferon-gamma biosynthetic process(GO:0045077)
0.1 10.2 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.1 5.2 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.0 0.3 GO:0071630 nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630)
0.0 4.3 GO:0090263 positive regulation of canonical Wnt signaling pathway(GO:0090263)
0.0 4.5 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.0 0.5 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.0 1.9 GO:0006779 porphyrin-containing compound biosynthetic process(GO:0006779) tetrapyrrole biosynthetic process(GO:0033014)
0.0 0.9 GO:0006903 vesicle targeting(GO:0006903)
0.0 2.9 GO:0046579 positive regulation of Ras protein signal transduction(GO:0046579)
0.0 0.8 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.0 1.5 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.0 1.1 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.0 0.8 GO:0002115 store-operated calcium entry(GO:0002115)
0.0 0.8 GO:0018345 protein palmitoylation(GO:0018345)
0.0 1.4 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
0.0 0.5 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.0 2.6 GO:0008306 associative learning(GO:0008306)
0.0 4.8 GO:0051017 actin filament bundle assembly(GO:0051017)
0.0 4.1 GO:0010977 negative regulation of neuron projection development(GO:0010977)
0.0 0.4 GO:0035428 hexose transmembrane transport(GO:0035428)
0.0 0.5 GO:0007141 male meiosis I(GO:0007141)
0.0 0.9 GO:0030431 sleep(GO:0030431)
0.0 0.7 GO:0009303 rRNA transcription(GO:0009303)
0.0 1.9 GO:0061077 chaperone-mediated protein folding(GO:0061077)
0.0 0.8 GO:0048741 skeletal muscle fiber development(GO:0048741)
0.0 0.2 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.0 1.4 GO:0017015 regulation of transforming growth factor beta receptor signaling pathway(GO:0017015)
0.0 0.6 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 3.1 GO:0000209 protein polyubiquitination(GO:0000209)
0.0 0.7 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0 0.2 GO:0010603 regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.0 1.1 GO:0051965 positive regulation of synapse assembly(GO:0051965)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 7.5 GO:1990032 parallel fiber(GO:1990032)
1.0 2.9 GO:0005584 collagen type I trimer(GO:0005584)
0.9 13.5 GO:0032009 early phagosome(GO:0032009)
0.7 3.7 GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
0.7 5.6 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.5 2.3 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.4 9.3 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.3 5.6 GO:0043203 axon hillock(GO:0043203)
0.3 1.9 GO:0008091 spectrin(GO:0008091)
0.3 7.9 GO:0043196 varicosity(GO:0043196)
0.3 4.0 GO:0098839 postsynaptic density membrane(GO:0098839)
0.2 2.3 GO:0030478 actin cap(GO:0030478)
0.2 5.5 GO:0035253 ciliary rootlet(GO:0035253)
0.2 11.4 GO:0048786 presynaptic active zone(GO:0048786)
0.2 1.3 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.2 6.7 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.2 1.0 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.2 5.5 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.2 4.0 GO:0071564 npBAF complex(GO:0071564)
0.2 7.7 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 0.4 GO:0098855 HCN channel complex(GO:0098855)
0.1 2.2 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.1 0.8 GO:0031310 integral component of vacuolar membrane(GO:0031166) intrinsic component of vacuolar membrane(GO:0031310)
0.1 1.5 GO:0001739 sex chromatin(GO:0001739)
0.1 5.2 GO:0030904 retromer complex(GO:0030904)
0.1 1.1 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.1 7.8 GO:0044295 axonal growth cone(GO:0044295)
0.1 0.4 GO:0031417 NatC complex(GO:0031417)
0.1 0.5 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.1 1.6 GO:0005641 nuclear envelope lumen(GO:0005641)
0.1 2.3 GO:0032839 dendrite cytoplasm(GO:0032839)
0.1 0.5 GO:0071547 piP-body(GO:0071547)
0.1 1.4 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 38.0 GO:0060076 excitatory synapse(GO:0060076)
0.1 4.5 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.1 1.0 GO:0097542 ciliary tip(GO:0097542)
0.1 0.8 GO:0002177 manchette(GO:0002177)
0.1 6.3 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.1 3.5 GO:0001772 immunological synapse(GO:0001772)
0.1 3.6 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 0.6 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.1 0.7 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 1.6 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 3.9 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.0 1.8 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 1.0 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 4.1 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 1.5 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 3.7 GO:0031594 neuromuscular junction(GO:0031594)
0.0 4.5 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 5.1 GO:0016605 PML body(GO:0016605)
0.0 0.9 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 5.0 GO:0043679 axon terminus(GO:0043679)
0.0 0.7 GO:0071004 U2-type prespliceosome(GO:0071004)
0.0 5.8 GO:0005884 actin filament(GO:0005884)
0.0 2.8 GO:0031526 brush border membrane(GO:0031526)
0.0 0.3 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.0 2.0 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.9 GO:0005771 multivesicular body(GO:0005771)
0.0 0.1 GO:0005638 lamin filament(GO:0005638)
0.0 2.3 GO:0030018 Z disc(GO:0030018)
0.0 0.9 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.3 GO:0048188 Set1C/COMPASS complex(GO:0048188)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 5.0 GO:0086059 voltage-gated calcium channel activity involved SA node cell action potential(GO:0086059)
1.2 3.7 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
1.1 4.3 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
1.0 4.9 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
1.0 3.9 GO:0050309 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.9 7.5 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.8 5.6 GO:0097016 L27 domain binding(GO:0097016)
0.8 2.4 GO:0004500 dopamine beta-monooxygenase activity(GO:0004500)
0.8 2.4 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.7 2.2 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.7 7.9 GO:0031749 D2 dopamine receptor binding(GO:0031749)
0.6 1.8 GO:0035276 ethanol binding(GO:0035276)
0.6 2.9 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.6 2.3 GO:0045159 myosin II binding(GO:0045159)
0.6 2.9 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.5 2.2 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.5 6.7 GO:0051430 corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.5 1.5 GO:0001729 ceramide kinase activity(GO:0001729)
0.5 1.9 GO:0004092 carnitine O-acetyltransferase activity(GO:0004092)
0.5 2.3 GO:0051373 FATZ binding(GO:0051373)
0.5 5.0 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.4 4.5 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.4 2.2 GO:0015189 L-lysine transmembrane transporter activity(GO:0015189)
0.4 3.0 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.4 4.1 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.4 3.8 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.4 2.3 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.4 2.3 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.3 2.8 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.3 1.0 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.3 1.4 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.3 1.1 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.2 0.7 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.2 2.0 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.2 4.6 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.2 2.8 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.2 2.8 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.2 3.5 GO:0033549 MAP kinase phosphatase activity(GO:0033549)
0.2 1.1 GO:0004483 mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483)
0.2 1.0 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.2 2.9 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.2 6.0 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.2 3.9 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.2 1.6 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.2 5.3 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.2 0.5 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.1 0.9 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.1 12.0 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.1 3.8 GO:0015026 coreceptor activity(GO:0015026)
0.1 0.8 GO:0045322 unmethylated CpG binding(GO:0045322)
0.1 3.0 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.1 0.5 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
0.1 1.5 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.1 1.4 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.1 1.4 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.1 1.2 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 1.9 GO:0048406 nerve growth factor binding(GO:0048406)
0.1 0.9 GO:0008823 ferric-chelate reductase activity(GO:0000293) cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.1 0.3 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.1 2.7 GO:0004707 MAP kinase activity(GO:0004707)
0.1 2.2 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.1 4.5 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.1 14.6 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 1.9 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1 4.0 GO:0005109 frizzled binding(GO:0005109)
0.1 2.1 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.1 1.2 GO:0070878 primary miRNA binding(GO:0070878)
0.1 6.1 GO:0031593 polyubiquitin binding(GO:0031593)
0.1 0.4 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.1 4.1 GO:0030507 spectrin binding(GO:0030507)
0.1 7.0 GO:0035254 glutamate receptor binding(GO:0035254)
0.1 1.8 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.1 0.9 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.1 6.2 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.1 4.1 GO:0042169 SH2 domain binding(GO:0042169)
0.1 5.0 GO:0015459 potassium channel regulator activity(GO:0015459)
0.1 0.6 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.1 4.7 GO:0008375 acetylglucosaminyltransferase activity(GO:0008375)
0.1 0.8 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.1 2.4 GO:0017091 AU-rich element binding(GO:0017091)
0.1 3.7 GO:0048365 Rac GTPase binding(GO:0048365)
0.1 0.9 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.1 0.7 GO:0001054 RNA polymerase I activity(GO:0001054)
0.1 8.5 GO:0044325 ion channel binding(GO:0044325)
0.0 1.3 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 2.1 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.5 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 5.2 GO:0005262 calcium channel activity(GO:0005262)
0.0 1.5 GO:0008483 transaminase activity(GO:0008483)
0.0 0.6 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.4 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.8 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.5 GO:0070628 proteasome binding(GO:0070628)
0.0 3.4 GO:0003777 microtubule motor activity(GO:0003777)
0.0 2.0 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 4.6 GO:0004713 protein tyrosine kinase activity(GO:0004713)
0.0 0.6 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.0 1.6 GO:0017048 Rho GTPase binding(GO:0017048)
0.0 2.5 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.0 7.3 GO:0030246 carbohydrate binding(GO:0030246)
0.0 0.8 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 3.0 GO:0008565 protein transporter activity(GO:0008565)
0.0 5.6 GO:0008017 microtubule binding(GO:0008017)
0.0 1.4 GO:0070888 E-box binding(GO:0070888)
0.0 2.0 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.4 GO:0005351 sugar:proton symporter activity(GO:0005351)
0.0 2.0 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 0.2 GO:0016594 glycine binding(GO:0016594)
0.0 1.0 GO:0043022 ribosome binding(GO:0043022)
0.0 0.2 GO:0003993 acid phosphatase activity(GO:0003993)
0.0 0.8 GO:0001221 transcription cofactor binding(GO:0001221)
0.0 2.1 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.5 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.2 2.4 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.2 12.7 PID RAS PATHWAY Regulation of Ras family activation
0.2 10.7 PID NCADHERIN PATHWAY N-cadherin signaling events
0.2 10.7 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.2 5.6 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.2 12.9 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.1 11.7 PID RHOA REG PATHWAY Regulation of RhoA activity
0.1 5.5 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.1 5.9 PID LKB1 PATHWAY LKB1 signaling events
0.1 5.8 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.1 2.5 PID REELIN PATHWAY Reelin signaling pathway
0.1 1.3 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 3.8 PID BMP PATHWAY BMP receptor signaling
0.0 3.0 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 1.5 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 1.6 ST G ALPHA I PATHWAY G alpha i Pathway
0.0 0.5 PID ALK1 PATHWAY ALK1 signaling events
0.0 5.6 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.0 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.5 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 0.4 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 4.8 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.1 PID CDC42 PATHWAY CDC42 signaling events
0.0 0.7 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.7 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 7.9 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.4 8.2 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.3 5.2 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.3 13.1 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.3 0.9 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.2 2.4 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.2 5.0 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.2 3.5 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.2 2.7 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.2 4.5 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.2 2.3 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.2 2.8 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.2 1.3 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.2 5.5 REACTOME KINESINS Genes involved in Kinesins
0.2 3.7 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.1 2.5 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.1 4.6 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.1 5.5 REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.1 2.3 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1 1.8 REACTOME PLC BETA MEDIATED EVENTS Genes involved in PLC beta mediated events
0.1 2.2 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.1 5.7 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.1 2.0 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 2.3 REACTOME AMYLOIDS Genes involved in Amyloids
0.1 3.2 REACTOME DAG AND IP3 SIGNALING Genes involved in DAG and IP3 signaling
0.1 4.3 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.1 1.9 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.1 1.3 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.1 4.0 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.1 2.8 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.1 5.1 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.1 2.2 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.1 1.9 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 1.2 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 2.2 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 2.3 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 1.9 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.4 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 7.8 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.9 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 4.9 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.7 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 0.9 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
0.0 0.2 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 0.8 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation