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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Tfap2d

Z-value: 0.94

Motif logo

Transcription factors associated with Tfap2d

Gene Symbol Gene ID Gene Info
ENSMUSG00000042596.8 Tfap2d

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Tfap2dmm39_v1_chr1_+_19173246_191732670.047.1e-01Click!

Activity profile of Tfap2d motif

Sorted Z-values of Tfap2d motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Tfap2d

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr2_-_163760603 6.04 ENSMUST00000044734.3
regulating synaptic membrane exocytosis 4
chrX_+_93278526 4.09 ENSMUST00000113908.8
ENSMUST00000113916.10
kelch-like 15
chr5_+_34445944 4.04 ENSMUST00000207754.2
cilia and flagella associated protein 99
chr3_+_37117676 3.94 ENSMUST00000144629.8
adenosine deaminase domain containing 1 (testis specific)
chr2_+_92430043 3.88 ENSMUST00000065797.7
carbohydrate sulfotransferase 1
chrX_+_93278588 3.85 ENSMUST00000096369.10
ENSMUST00000113911.9
kelch-like 15
chr3_+_37117779 3.84 ENSMUST00000029274.14
adenosine deaminase domain containing 1 (testis specific)
chr2_+_155907658 3.70 ENSMUST00000137966.2
sperm associated antigen 4
chr16_-_38533597 3.67 ENSMUST00000023487.5
Rho GTPase activating protein 31
chr2_+_9887427 3.67 ENSMUST00000114919.2
RIKEN cDNA 4930412O13 gene
chr11_-_109613040 3.64 ENSMUST00000020938.8
FAM20A, golgi associated secretory pathway pseudokinase
chr5_+_114706077 3.36 ENSMUST00000043650.8
family with sequence similarity 222, member A
chr8_+_94537460 3.32 ENSMUST00000034198.15
ENSMUST00000125716.8
guanine nucleotide binding protein, alpha O
chrX_+_93278203 3.22 ENSMUST00000153900.8
kelch-like 15
chr8_+_86219191 3.19 ENSMUST00000034136.12
glutamic pyruvate transaminase (alanine aminotransferase) 2
chr7_+_106969950 3.18 ENSMUST00000073459.12
synaptotagmin IX
chr3_-_107366868 3.16 ENSMUST00000009617.10
ENSMUST00000238670.2
potassium voltage gated channel, Shaw-related subfamily, member 4
chr15_+_39061612 2.94 ENSMUST00000082054.12
ENSMUST00000227243.2
ENSMUST00000042917.10
regulating synaptic membrane exocytosis 2
chr11_-_97391166 2.94 ENSMUST00000056955.2
RIKEN cDNA 4933428G20 gene
chr11_+_98277276 2.90 ENSMUST00000041301.8
phenylethanolamine-N-methyltransferase
chr14_+_73790105 2.89 ENSMUST00000160507.8
ENSMUST00000022706.7
succinate-Coenzyme A ligase, ADP-forming, beta subunit
chr12_+_103498542 2.81 ENSMUST00000021631.12
protein phosphatase 4, regulatory subunit 4
chr3_+_40904253 2.75 ENSMUST00000048490.13
La ribonucleoprotein domain family, member 1B
chr3_-_54962458 2.70 ENSMUST00000199352.2
ENSMUST00000198320.5
ENSMUST00000029368.7
cyclin A1
chr11_+_103664976 2.64 ENSMUST00000000127.6
wingless-type MMTV integration site family, member 3
chr2_-_35994819 2.60 ENSMUST00000148852.4
LIM homeobox protein 6
chr16_-_18405709 2.60 ENSMUST00000232335.2
T-box 1
chr5_+_16139760 2.57 ENSMUST00000101581.10
ENSMUST00000039370.14
ENSMUST00000199704.5
ENSMUST00000180204.8
ENSMUST00000078272.13
ENSMUST00000115281.7
calcium channel, voltage-dependent, alpha2/delta subunit 1
chr2_+_91087668 2.56 ENSMUST00000111349.9
ENSMUST00000131711.8
protein kinase C and casein kinase substrate in neurons 3
chr19_-_10582672 2.52 ENSMUST00000236478.2
ENSMUST00000236950.2
triokinase, FMN cyclase
chr6_-_72876269 2.51 ENSMUST00000204598.3
potassium channel modulatory factor 1
chr12_+_71158192 2.47 ENSMUST00000021482.6
translocase of outer mitochondrial membrane 20-like
chr9_-_29323032 2.46 ENSMUST00000115236.2
neurotrimin
chr2_+_155907100 2.45 ENSMUST00000038860.12
sperm associated antigen 4
chr4_-_108637700 2.40 ENSMUST00000106658.8
zinc finger, FYVE domain containing 9
chr8_-_65146079 2.29 ENSMUST00000048967.9
carboxypeptidase E
chr16_+_17464428 2.27 ENSMUST00000182117.8
ENSMUST00000182671.8
ENSMUST00000182344.8
coiled-coil domain containing 74A
chr4_-_108637979 2.24 ENSMUST00000106657.8
zinc finger, FYVE domain containing 9
chr6_-_88851579 2.24 ENSMUST00000061262.11
ENSMUST00000140455.8
ENSMUST00000145780.2
podocalyxin-like 2
chr19_-_4748696 2.19 ENSMUST00000225896.2
ENSMUST00000177696.8
predicted gene 960
chr4_-_46991842 2.17 ENSMUST00000107749.4
gamma-aminobutyric acid (GABA) B receptor, 2
chr5_+_119808890 2.15 ENSMUST00000121021.8
T-box 3
chr5_+_119808722 2.13 ENSMUST00000079719.11
T-box 3
chr16_+_17464328 2.12 ENSMUST00000056962.11
coiled-coil domain containing 74A
chr14_-_19420488 2.10 ENSMUST00000166494.2
predicted gene 2897
chr13_-_58421910 2.08 ENSMUST00000224505.2
G kinase anchoring protein 1
chr7_+_118454957 2.06 ENSMUST00000208658.2
ENSMUST00000098087.9
ENSMUST00000106547.2
IQ motif containing K
chr11_+_69826603 2.01 ENSMUST00000018698.12
Y box protein 2
chr10_-_31485180 2.00 ENSMUST00000081989.8
ring finger protein 217
chr2_-_104324745 2.00 ENSMUST00000028600.14
homeodomain interacting protein kinase 3
chr1_-_157240138 1.99 ENSMUST00000078308.13
RAS protein activator like 2
chr14_+_14901127 1.95 ENSMUST00000163790.2
predicted gene 3558
chr5_-_24806960 1.94 ENSMUST00000030791.12
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
chr2_-_35995283 1.92 ENSMUST00000112960.8
ENSMUST00000112967.12
ENSMUST00000112963.8
LIM homeobox protein 6
chr2_-_32872019 1.91 ENSMUST00000153484.7
solute carrier family 2, (facilitated glucose transporter), member 8
chr9_+_51959534 1.89 ENSMUST00000061352.11
radixin
chr8_-_121361097 1.87 ENSMUST00000123927.9
RIKEN cDNA 1190005I06 gene
chr5_+_34817704 1.86 ENSMUST00000074651.11
ENSMUST00000001112.14
G protein-coupled receptor kinase 4
chr9_-_29323500 1.85 ENSMUST00000115237.8
neurotrimin
chr7_+_106969919 1.81 ENSMUST00000137663.2
synaptotagmin IX
chrX_+_85235370 1.80 ENSMUST00000026036.5
nuclear receptor subfamily 0, group B, member 1
chr3_+_9315662 1.79 ENSMUST00000155203.2
zinc finger and BTB domain containing 10
chr2_-_32872032 1.79 ENSMUST00000195863.2
ENSMUST00000028129.13
solute carrier family 2, (facilitated glucose transporter), member 8
chr14_-_18817743 1.78 ENSMUST00000167430.8
predicted gene 3020
chr14_-_24054927 1.76 ENSMUST00000145596.3
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr5_+_28370687 1.71 ENSMUST00000036177.9
engrailed 2
chr1_-_60082246 1.71 ENSMUST00000027172.13
ENSMUST00000191251.7
islet cell autoantigen 1-like
chr10_+_11219117 1.68 ENSMUST00000069106.5
epilepsy, progressive myoclonic epilepsy, type 2 gene alpha
chr8_-_124242194 1.67 ENSMUST00000176286.8
ENSMUST00000176155.2
dysbindin (dystrobrevin binding protein 1) domain containing 1
chr4_-_41640321 1.65 ENSMUST00000127306.2
energy homeostasis associated
chr14_+_16508028 1.65 ENSMUST00000163885.2
predicted gene 3248
chr6_+_72332423 1.63 ENSMUST00000069695.9
ENSMUST00000132243.3
transmembrane protein 150A
chr6_-_88852017 1.62 ENSMUST00000145944.3
podocalyxin-like 2
chr14_-_19261196 1.61 ENSMUST00000112797.12
ENSMUST00000225885.2
RIKEN cDNA D830030K20 gene
chr2_+_119572770 1.59 ENSMUST00000028758.8
inositol 1,4,5-trisphosphate 3-kinase A
chr13_+_47276132 1.58 ENSMUST00000068891.12
ring finger protein 144B
chr5_-_122187884 1.57 ENSMUST00000111752.10
cut-like homeobox 2
chr8_-_124242072 1.55 ENSMUST00000177240.8
dysbindin (dystrobrevin binding protein 1) domain containing 1
chr6_-_56339251 1.53 ENSMUST00000166102.8
phosphodiesterase 1C
chr5_+_108842294 1.50 ENSMUST00000013633.12
fibroblast growth factor receptor-like 1
chr2_+_84489890 1.50 ENSMUST00000133437.3
BTB (POZ) domain containing 18
chr5_-_22549688 1.49 ENSMUST00000062372.14
ENSMUST00000161356.8
reelin
chr2_-_9888804 1.48 ENSMUST00000114915.3
RIKEN cDNA 9230102O04 gene
chr7_+_65511777 1.48 ENSMUST00000055576.12
ENSMUST00000098391.11
proprotein convertase subtilisin/kexin type 6
chr19_-_10582773 1.47 ENSMUST00000237788.2
triokinase, FMN cyclase
chr14_+_16589391 1.47 ENSMUST00000164484.8
predicted gene 8237
chr6_+_50087167 1.47 ENSMUST00000166318.8
ENSMUST00000036236.15
ENSMUST00000204545.3
ENSMUST00000036225.15
membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)
chr18_+_82928959 1.43 ENSMUST00000171238.8
zinc finger protein 516
chr13_-_69147639 1.41 ENSMUST00000022013.8
adenylate cyclase 2
chr2_-_44817173 1.40 ENSMUST00000130991.8
glycosyltransferase-like domain containing 1
chr2_-_146927365 1.39 ENSMUST00000067020.3
NK2 homeobox 4
chr9_+_54606832 1.38 ENSMUST00000070070.8
DnaJ heat shock protein family (Hsp40) member A4
chr7_+_128858730 1.38 ENSMUST00000094018.6
ENSMUST00000205896.2
phospholipid phosphatase 4
chr8_+_70354828 1.38 ENSMUST00000050373.7
testis-specific serine kinase 6
chr9_+_54606798 1.37 ENSMUST00000154690.8
DnaJ heat shock protein family (Hsp40) member A4
chr5_+_16139909 1.36 ENSMUST00000196750.2
calcium channel, voltage-dependent, alpha2/delta subunit 1
chr9_-_58943670 1.36 ENSMUST00000214547.2
ENSMUST00000068664.7
neogenin
chr6_+_72332449 1.33 ENSMUST00000206064.2
transmembrane protein 150A
chr2_+_24839758 1.31 ENSMUST00000028350.9
zinc finger, MYND domain containing 19
chr2_+_27567213 1.29 ENSMUST00000077257.12
retinoid X receptor alpha
chr2_+_167922924 1.26 ENSMUST00000052125.7
par-6 family cell polarity regulator beta
chr7_+_65294630 1.24 ENSMUST00000032728.9
threonyl-tRNA synthetase-like 2
chr10_-_114638202 1.22 ENSMUST00000239411.2
TRH-degrading enzyme
chr11_+_77821626 1.20 ENSMUST00000093995.10
ENSMUST00000000646.14
seizure related gene 6
chr19_-_5148506 1.19 ENSMUST00000025805.8
cornichon family AMPA receptor auxiliary protein 2
chr2_-_162502994 1.19 ENSMUST00000109442.8
ENSMUST00000109445.9
ENSMUST00000109443.8
ENSMUST00000109441.2
protein tyrosine phosphatase, receptor type, T
chr2_-_73605684 1.19 ENSMUST00000112024.10
ENSMUST00000180045.8
chimerin 1
chr8_+_93084253 1.18 ENSMUST00000210246.2
ENSMUST00000034184.12
Iroquois homeobox 5
chr11_+_117545618 1.18 ENSMUST00000106344.8
trinucleotide repeat containing 6C
chr6_-_52168675 1.15 ENSMUST00000101395.3
homeobox A4
chr19_-_5474787 1.14 ENSMUST00000148219.9
Dr1 associated protein 1 (negative cofactor 2 alpha)
chr9_-_43117052 1.14 ENSMUST00000176636.5
POU domain, class 2, transcription factor 3
chr5_+_88712840 1.14 ENSMUST00000196894.5
ENSMUST00000198965.5
RUN and FYVE domain containing 3
chr4_+_13743424 1.13 ENSMUST00000006761.10
RUNX1 translocation partner 1
chr13_+_119565669 1.13 ENSMUST00000173627.8
ENSMUST00000126957.9
ENSMUST00000174691.8
polyadenylate binding protein-interacting protein 1
chr2_-_26096547 1.11 ENSMUST00000028302.8
LIM homeobox protein 3
chr14_-_19057159 1.10 ENSMUST00000170123.2
predicted gene 10409
chr2_+_90677499 1.09 ENSMUST00000136872.8
ENSMUST00000150232.8
ENSMUST00000111467.4
mitochondrial carrier 2
chr5_+_32768515 1.09 ENSMUST00000202543.4
ENSMUST00000072311.13
YES proto-oncogene 1, Src family tyrosine kinase
chr17_-_13271183 1.09 ENSMUST00000091648.4
G protein-coupled receptor 31, D17Leh66b region
chr10_-_120815232 1.08 ENSMUST00000119944.8
ENSMUST00000119093.2
LEM domain containing 3
chr16_+_65612394 1.07 ENSMUST00000227997.2
vestigial like family member 3
chr4_+_152093260 1.07 ENSMUST00000097773.4
kelch-like 21
chr2_-_151474391 1.05 ENSMUST00000137936.2
ENSMUST00000146172.8
ENSMUST00000094456.10
ENSMUST00000148755.8
ENSMUST00000109875.8
ENSMUST00000028951.14
ENSMUST00000109877.10
syntaphilin
chr4_+_84802650 1.04 ENSMUST00000169371.9
centlein, centrosomal protein
chr5_+_141227245 1.04 ENSMUST00000085774.11
sidekick cell adhesion molecule 1
chr14_-_16968099 1.03 ENSMUST00000181562.8
predicted gene, 3488
chr9_+_106354463 1.03 ENSMUST00000047721.10
ribosomal RNA processing 9, U3 small nucleolar RNA binding protein
chr19_-_37340010 1.03 ENSMUST00000131070.3
insulin degrading enzyme
chr19_-_50666923 1.02 ENSMUST00000211687.2
ENSMUST00000211008.2
ENSMUST00000111756.4
ENSMUST00000209783.2
sortilin-related VPS10 domain containing receptor 1
chr17_-_29456750 1.02 ENSMUST00000137727.3
copine V
chr7_+_65511482 1.01 ENSMUST00000176199.8
proprotein convertase subtilisin/kexin type 6
chr13_+_112937320 1.00 ENSMUST00000016144.12
phospholipid phosphatase 1
chr3_-_105594865 0.99 ENSMUST00000090680.11
DEAD box helicase 20
chr8_+_84699580 0.99 ENSMUST00000005606.8
protein kinase, cAMP dependent, catalytic, alpha
chr18_+_82929037 0.99 ENSMUST00000236858.2
zinc finger protein 516
chr12_+_112978051 0.99 ENSMUST00000223502.2
ENSMUST00000084891.5
ENSMUST00000220541.2
phosphofurin acidic cluster sorting protein 2
chr8_+_80366247 0.99 ENSMUST00000173078.8
ENSMUST00000173286.8
OTU domain containing 4
chr14_+_15579811 0.98 ENSMUST00000171906.2
predicted gene 3667
chr16_-_4238280 0.98 ENSMUST00000120080.8
adenylate cyclase 9
chr6_-_30936013 0.97 ENSMUST00000101589.5
Kruppel-like factor 14
chr5_-_36641456 0.97 ENSMUST00000119916.2
ENSMUST00000031097.8
transcriptional adaptor 2B
chr14_-_31552608 0.97 ENSMUST00000014640.9
ankyrin repeat domain 28
chr14_-_24053994 0.96 ENSMUST00000225431.2
ENSMUST00000188210.8
ENSMUST00000224787.2
ENSMUST00000225315.2
ENSMUST00000225556.2
ENSMUST00000223727.2
ENSMUST00000223655.2
ENSMUST00000224077.2
ENSMUST00000224812.2
ENSMUST00000224285.2
ENSMUST00000225471.2
ENSMUST00000224232.2
ENSMUST00000223749.2
ENSMUST00000224025.2
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr12_+_53294940 0.95 ENSMUST00000223358.3
neuronal PAS domain protein 3
chr14_-_24054273 0.95 ENSMUST00000188285.7
ENSMUST00000190044.7
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr19_-_5474509 0.94 ENSMUST00000136579.3
ENSMUST00000113673.9
Dr1 associated protein 1 (negative cofactor 2 alpha)
chr18_-_25886750 0.94 ENSMUST00000224553.2
ENSMUST00000025117.14
CUGBP, Elav-like family member 4
chr15_+_87428483 0.91 ENSMUST00000230414.2
TAFA chemokine like family member 5
chr15_-_31367872 0.91 ENSMUST00000123325.9
ankyrin repeat domain 33B
chr14_-_24054186 0.91 ENSMUST00000188991.7
ENSMUST00000224468.2
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr9_+_107277242 0.90 ENSMUST00000166799.8
ENSMUST00000170737.3
calcium channel, voltage-dependent, alpha 2/delta subunit 2
chr17_+_87415049 0.90 ENSMUST00000041369.8
ENSMUST00000234803.2
suppressor of cytokine signaling 5
chr12_+_95658987 0.90 ENSMUST00000057324.4
fibronectin leucine rich transmembrane protein 2
chr15_+_34837501 0.90 ENSMUST00000072868.5
K+ voltage-gated channel, subfamily S, 2
chr17_-_66826661 0.89 ENSMUST00000167962.2
ENSMUST00000070538.12
RAB12, member RAS oncogene family
chr5_+_100994230 0.88 ENSMUST00000092990.4
ENSMUST00000145612.2
glycerol-3-phosphate acyltransferase 3
chr8_+_36924702 0.87 ENSMUST00000135373.8
ENSMUST00000147525.9
tRNA methyltransferase 9B
chr2_+_30061469 0.87 ENSMUST00000015481.6
endonuclease G
chr12_+_13319110 0.87 ENSMUST00000042953.10
neuroblastoma amplified sequence
chr10_+_95350975 0.86 ENSMUST00000099329.5
ubiquitin-conjugating enzyme E2N
chr5_-_76452365 0.86 ENSMUST00000075159.5
circadian locomotor output cycles kaput
chr11_-_72686853 0.86 ENSMUST00000156294.8
cytochrome b5 domain containing 2
chr5_+_37399284 0.85 ENSMUST00000202434.4
ENSMUST00000114158.9
collapsin response mediator protein 1
chr18_-_81029986 0.85 ENSMUST00000057950.9
spalt like transcription factor 3
chr7_-_37472290 0.84 ENSMUST00000176205.8
zinc finger protein 536
chr4_+_59626185 0.84 ENSMUST00000070150.11
ENSMUST00000052420.7
RIKEN cDNA E130308A19 gene
chr19_-_10434837 0.83 ENSMUST00000171400.4
leucine rich repeat containing 10B
chr14_+_15295240 0.82 ENSMUST00000172431.8
predicted gene 3512
chr7_-_64806164 0.81 ENSMUST00000148459.3
ENSMUST00000119118.8
family with sequence similarity 189, member A1
chr19_-_34856853 0.80 ENSMUST00000036584.13
pantothenate kinase 1
chr6_+_72333209 0.80 ENSMUST00000206531.2
transmembrane protein 150A
chr12_+_103354915 0.79 ENSMUST00000101094.9
ENSMUST00000021620.13
OTU domain, ubiquitin aldehyde binding 2
chr11_+_49500090 0.79 ENSMUST00000020617.3
FMS-like tyrosine kinase 4
chr2_+_27567246 0.79 ENSMUST00000166775.8
retinoid X receptor alpha
chr13_-_30170031 0.78 ENSMUST00000102948.11
E2F transcription factor 3
chr5_-_72716942 0.78 ENSMUST00000074948.5
ENSMUST00000087216.12
nuclear transcription factor, X-box binding-like 1
chr4_+_84802592 0.78 ENSMUST00000102819.10
centlein, centrosomal protein
chr12_+_84161095 0.78 ENSMUST00000123491.8
ENSMUST00000046340.9
ENSMUST00000136159.2
dynein, axonemal, light chain 1
chr7_-_34914675 0.77 ENSMUST00000118444.3
ENSMUST00000122409.8
low density lipoprotein receptor-related protein 3
chr6_-_113172340 0.77 ENSMUST00000162280.2
lipoma HMGIC fusion partner-like protein 4
chr2_-_80411578 0.76 ENSMUST00000028386.12
NCK-associated protein 1
chr11_+_11065782 0.76 ENSMUST00000056344.5
von Willebrand factor C domain containing 2
chr14_-_18135010 0.75 ENSMUST00000165466.8
RIKEN cDNA 2610042L04 gene
chr4_+_84802513 0.75 ENSMUST00000047023.13
centlein, centrosomal protein
chr10_-_32765671 0.75 ENSMUST00000218645.2
Na+/K+ transporting ATPase interacting 2
chr4_+_115642147 0.75 ENSMUST00000239030.2
ATP synthase mitochondrial F1 complex assembly factor 1
chr11_-_107685383 0.75 ENSMUST00000021066.4
calcium channel, voltage-dependent, gamma subunit 4
chr5_-_100563974 0.74 ENSMUST00000182886.8
ENSMUST00000094578.11
Sec31 homolog A (S. cerevisiae)
chr7_+_40547608 0.74 ENSMUST00000044705.12
V-set and transmembrane domain containing 2B
chr11_-_35689711 0.74 ENSMUST00000160726.4
fibrillarin-like 1
chr19_-_50667079 0.74 ENSMUST00000209413.2
ENSMUST00000072685.13
ENSMUST00000164039.9
sortilin-related VPS10 domain containing receptor 1
chr5_-_123038329 0.74 ENSMUST00000031435.14
lysine (K)-specific demethylase 2B
chr14_-_20844074 0.72 ENSMUST00000080440.14
ENSMUST00000100837.11
ENSMUST00000071816.7
calcium/calmodulin-dependent protein kinase II gamma
chr14_-_18897750 0.72 ENSMUST00000178728.2
predicted gene 3005
chr11_+_59738866 0.72 ENSMUST00000102695.4
5',3'-nucleotidase, mitochondrial
chr6_+_107506678 0.70 ENSMUST00000049285.10
leucine rich repeat protein 1, neuronal
chr4_+_141095415 0.70 ENSMUST00000006380.5
family with sequence similarity 131, member C
chr7_-_141055044 0.69 ENSMUST00000043870.9
polymerase (RNA) II (DNA directed) polypeptide L
chr7_+_141055135 0.69 ENSMUST00000026585.14
tetraspanin 4

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 11.2 GO:0071630 nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630)
1.4 4.3 GO:0003167 atrioventricular bundle cell differentiation(GO:0003167)
1.1 3.2 GO:1904456 negative regulation of neuronal action potential(GO:1904456)
1.0 3.9 GO:0042339 keratan sulfate metabolic process(GO:0042339)
0.9 3.7 GO:0015755 fructose transport(GO:0015755)
0.9 2.6 GO:1904954 canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation(GO:1904954)
0.9 2.6 GO:0021644 vagus nerve morphogenesis(GO:0021644)
0.8 3.2 GO:0042851 L-alanine metabolic process(GO:0042851)
0.8 3.9 GO:0086048 membrane depolarization during bundle of His cell action potential(GO:0086048)
0.8 4.7 GO:0060082 response to carbon monoxide(GO:0034465) eye blink reflex(GO:0060082)
0.8 2.3 GO:0030070 insulin processing(GO:0030070)
0.7 2.8 GO:0080163 regulation of protein serine/threonine phosphatase activity(GO:0080163)
0.7 4.0 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
0.6 2.9 GO:0042414 epinephrine metabolic process(GO:0042414)
0.6 4.5 GO:0021853 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.5 2.2 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.5 2.5 GO:0035927 RNA import into mitochondrion(GO:0035927)
0.4 2.1 GO:0045994 regulation of translational initiation by iron(GO:0006447) positive regulation of translational initiation by iron(GO:0045994)
0.4 2.5 GO:0032902 nerve growth factor production(GO:0032902)
0.4 1.2 GO:0006435 threonyl-tRNA aminoacylation(GO:0006435)
0.4 6.1 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.4 1.5 GO:0097477 lateral motor column neuron migration(GO:0097477)
0.3 2.0 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.3 1.2 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.3 1.2 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.3 2.9 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
0.3 1.7 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.3 1.9 GO:0003219 cardiac right ventricle formation(GO:0003219)
0.3 1.1 GO:0021526 medial motor column neuron differentiation(GO:0021526)
0.3 14.0 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.3 2.1 GO:0007199 G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger(GO:0007199)
0.3 1.5 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.2 0.7 GO:0034963 box C/D snoRNA 3'-end processing(GO:0000494) box C/D snoRNA metabolic process(GO:0033967) box C/D snoRNA processing(GO:0034963) histone glutamine methylation(GO:1990258)
0.2 1.9 GO:1902966 regulation of protein localization to early endosome(GO:1902965) positive regulation of protein localization to early endosome(GO:1902966)
0.2 3.6 GO:0070166 enamel mineralization(GO:0070166)
0.2 0.8 GO:1904616 regulation of actin filament binding(GO:1904529) regulation of actin binding(GO:1904616)
0.2 1.3 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
0.2 1.8 GO:0035902 response to immobilization stress(GO:0035902)
0.2 1.7 GO:0046959 habituation(GO:0046959)
0.2 0.7 GO:0021993 initiation of neural tube closure(GO:0021993)
0.2 0.5 GO:0036269 swimming behavior(GO:0036269)
0.2 0.7 GO:0006244 pyrimidine nucleotide catabolic process(GO:0006244) pyrimidine deoxyribonucleotide catabolic process(GO:0009223)
0.2 0.2 GO:0060423 foregut regionalization(GO:0060423) lung field specification(GO:0060424) lung induction(GO:0060492)
0.2 0.5 GO:0016561 protein import into peroxisome matrix, translocation(GO:0016561)
0.2 0.8 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.2 1.6 GO:0034398 telomere tethering at nuclear periphery(GO:0034398)
0.2 0.7 GO:0015766 disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.2 0.7 GO:0060849 regulation of transcription involved in lymphatic endothelial cell fate commitment(GO:0060849)
0.2 0.5 GO:1901994 negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.2 0.8 GO:0070602 regulation of centromeric sister chromatid cohesion(GO:0070602)
0.1 0.4 GO:0002654 positive regulation of tolerance induction dependent upon immune response(GO:0002654) regulation of peripheral tolerance induction(GO:0002658) positive regulation of peripheral tolerance induction(GO:0002660) regulation of peripheral T cell tolerance induction(GO:0002849) positive regulation of peripheral T cell tolerance induction(GO:0002851)
0.1 0.9 GO:1902512 positive regulation of apoptotic DNA fragmentation(GO:1902512)
0.1 2.6 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.1 1.0 GO:0071880 adenylate cyclase-activating adrenergic receptor signaling pathway(GO:0071880)
0.1 0.5 GO:2000384 regulation of ectoderm development(GO:2000383) negative regulation of ectoderm development(GO:2000384)
0.1 0.5 GO:0097168 condensed mesenchymal cell proliferation(GO:0072137) mesenchymal stem cell proliferation(GO:0097168)
0.1 0.9 GO:0060024 rhythmic synaptic transmission(GO:0060024)
0.1 0.9 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.1 0.9 GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.1 1.6 GO:0006020 inositol metabolic process(GO:0006020)
0.1 2.3 GO:0002031 G-protein coupled receptor internalization(GO:0002031)
0.1 4.1 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.1 1.0 GO:0010815 bradykinin catabolic process(GO:0010815)
0.1 1.7 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.1 1.7 GO:1990403 embryonic brain development(GO:1990403)
0.1 0.6 GO:0035795 negative regulation of mitochondrial membrane permeability(GO:0035795)
0.1 1.1 GO:0035701 hematopoietic stem cell migration(GO:0035701) hematopoietic stem cell homeostasis(GO:0061484)
0.1 0.7 GO:2000819 regulation of nucleotide-excision repair(GO:2000819)
0.1 0.8 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.1 1.0 GO:0090520 sphingolipid mediated signaling pathway(GO:0090520)
0.1 0.4 GO:0098582 innate vocalization behavior(GO:0098582)
0.1 0.9 GO:2000323 negative regulation of glucocorticoid receptor signaling pathway(GO:2000323)
0.1 3.9 GO:0050901 leukocyte tethering or rolling(GO:0050901)
0.1 1.0 GO:0090170 regulation of Golgi inheritance(GO:0090170)
0.1 1.7 GO:0035278 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.1 1.1 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.1 0.8 GO:1904378 maintenance of unfolded protein(GO:0036506) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
0.1 0.5 GO:0014870 response to inactivity(GO:0014854) response to muscle inactivity(GO:0014870) response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.1 0.3 GO:0072194 kidney smooth muscle tissue development(GO:0072194)
0.1 1.2 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.1 2.6 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.1 0.2 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.1 0.4 GO:1902303 negative regulation of potassium ion export(GO:1902303)
0.1 0.3 GO:0016240 autophagosome docking(GO:0016240)
0.1 0.3 GO:0035938 estradiol secretion(GO:0035938) regulation of estradiol secretion(GO:2000864)
0.1 1.6 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.1 1.4 GO:0035092 sperm chromatin condensation(GO:0035092)
0.1 0.4 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.1 0.9 GO:1902866 regulation of retina development in camera-type eye(GO:1902866)
0.1 0.6 GO:0002432 granuloma formation(GO:0002432)
0.1 1.0 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.1 0.1 GO:2001055 positive regulation of mesenchymal cell apoptotic process(GO:2001055)
0.1 0.1 GO:0060137 maternal process involved in parturition(GO:0060137)
0.1 0.4 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)
0.1 1.4 GO:0036120 cellular response to platelet-derived growth factor stimulus(GO:0036120)
0.1 1.7 GO:0007614 short-term memory(GO:0007614)
0.1 0.8 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.1 0.8 GO:0021891 olfactory bulb interneuron development(GO:0021891)
0.1 0.9 GO:0036158 outer dynein arm assembly(GO:0036158)
0.1 1.5 GO:0046069 cGMP catabolic process(GO:0046069)
0.1 0.6 GO:0060449 bud elongation involved in lung branching(GO:0060449)
0.1 0.8 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.1 0.8 GO:0090037 positive regulation of protein kinase C signaling(GO:0090037)
0.1 0.5 GO:0019348 dolichol metabolic process(GO:0019348)
0.1 3.8 GO:0009409 response to cold(GO:0009409)
0.1 1.2 GO:0042711 maternal behavior(GO:0042711)
0.1 1.0 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.1 0.8 GO:0060025 regulation of synaptic activity(GO:0060025)
0.1 1.5 GO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037) diaphragm development(GO:0060539)
0.1 0.4 GO:0045200 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.1 1.2 GO:0090036 regulation of protein kinase C signaling(GO:0090036)
0.0 9.8 GO:0007286 spermatid development(GO:0007286)
0.0 0.5 GO:0097623 potassium ion export across plasma membrane(GO:0097623)
0.0 0.5 GO:0002002 regulation of angiotensin levels in blood(GO:0002002)
0.0 0.5 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0 0.2 GO:0021564 vagus nerve development(GO:0021564)
0.0 0.8 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 1.4 GO:1902259 regulation of delayed rectifier potassium channel activity(GO:1902259)
0.0 0.7 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 1.0 GO:0048148 behavioral response to cocaine(GO:0048148)
0.0 0.9 GO:0000729 DNA double-strand break processing(GO:0000729)
0.0 0.2 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 1.1 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.0 0.1 GO:0046462 monoacylglycerol metabolic process(GO:0046462)
0.0 1.2 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 1.2 GO:0043171 peptide catabolic process(GO:0043171)
0.0 0.8 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 1.0 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.0 0.2 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.0 1.9 GO:0007520 myoblast fusion(GO:0007520)
0.0 0.3 GO:0045003 DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.0 0.4 GO:2000465 regulation of glycogen (starch) synthase activity(GO:2000465)
0.0 0.7 GO:1901897 regulation of relaxation of cardiac muscle(GO:1901897)
0.0 1.1 GO:0034629 cellular protein complex localization(GO:0034629)
0.0 1.2 GO:0046460 neutral lipid biosynthetic process(GO:0046460) acylglycerol biosynthetic process(GO:0046463)
0.0 0.0 GO:0018307 enzyme active site formation(GO:0018307)
0.0 0.3 GO:0090166 Golgi disassembly(GO:0090166)
0.0 0.3 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.0 1.5 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.0 0.1 GO:0023016 signal transduction by trans-phosphorylation(GO:0023016)
0.0 1.1 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.0 0.7 GO:0045723 positive regulation of fatty acid biosynthetic process(GO:0045723)
0.0 0.3 GO:0035879 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879)
0.0 1.0 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 0.3 GO:0042249 establishment of planar polarity of embryonic epithelium(GO:0042249)
0.0 0.7 GO:0071711 basement membrane organization(GO:0071711)
0.0 0.7 GO:0035115 embryonic forelimb morphogenesis(GO:0035115)
0.0 0.3 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.0 0.5 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.0 0.0 GO:0061762 CAMKK-AMPK signaling cascade(GO:0061762)
0.0 3.9 GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787)
0.0 0.9 GO:0019933 cAMP-mediated signaling(GO:0019933)
0.0 0.9 GO:0008333 endosome to lysosome transport(GO:0008333)
0.0 0.5 GO:0070534 protein K63-linked ubiquitination(GO:0070534)
0.0 0.2 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.0 0.8 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
0.0 0.5 GO:0008045 motor neuron axon guidance(GO:0008045)
0.0 0.4 GO:1902230 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)
0.0 0.1 GO:0015820 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.0 0.1 GO:0035106 operant conditioning(GO:0035106)
0.0 0.4 GO:0007184 SMAD protein import into nucleus(GO:0007184)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.7 GO:0097123 cyclin A1-CDK2 complex(GO:0097123)
0.4 2.2 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.4 1.3 GO:0098830 presynaptic endosome(GO:0098830)
0.4 7.3 GO:0031045 dense core granule(GO:0031045)
0.3 0.9 GO:0070939 Dsl1p complex(GO:0070939)
0.3 0.9 GO:0031372 UBC13-MMS2 complex(GO:0031372)
0.3 4.7 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.3 3.9 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.2 0.6 GO:0036488 CHOP-C/EBP complex(GO:0036488)
0.2 2.5 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.2 1.8 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.2 9.0 GO:0048786 presynaptic active zone(GO:0048786)
0.2 1.5 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.2 1.6 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.1 0.6 GO:0071149 TEAD-1-YAP complex(GO:0071148) TEAD-2-YAP complex(GO:0071149)
0.1 13.0 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 0.9 GO:0005726 perichromatin fibrils(GO:0005726)
0.1 0.4 GO:0097632 extrinsic component of pre-autophagosomal structure membrane(GO:0097632)
0.1 1.8 GO:0042788 polysomal ribosome(GO:0042788)
0.1 0.5 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.1 0.6 GO:0044614 nuclear pore cytoplasmic filaments(GO:0044614)
0.1 0.4 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.1 0.8 GO:0072379 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.1 1.0 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.1 2.3 GO:0043196 varicosity(GO:0043196)
0.1 1.0 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.1 0.8 GO:0036157 outer dynein arm(GO:0036157)
0.1 0.5 GO:0030689 Noc complex(GO:0030689)
0.1 1.0 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 1.1 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.1 0.8 GO:0031209 SCAR complex(GO:0031209)
0.0 0.7 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.7 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 1.1 GO:0071437 invadopodium(GO:0071437)
0.0 1.1 GO:0051286 cell tip(GO:0051286)
0.0 1.0 GO:0030914 STAGA complex(GO:0030914)
0.0 3.2 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 2.0 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 2.7 GO:0008287 protein serine/threonine phosphatase complex(GO:0008287) phosphatase complex(GO:1903293)
0.0 3.7 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.2 GO:0072487 MSL complex(GO:0072487)
0.0 0.3 GO:0033061 DNA recombinase mediator complex(GO:0033061)
0.0 2.0 GO:0005844 polysome(GO:0005844)
0.0 0.7 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.4 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.4 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 5.9 GO:0031514 motile cilium(GO:0031514)
0.0 0.9 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 1.0 GO:0042734 presynaptic membrane(GO:0042734)
0.0 0.5 GO:0071564 npBAF complex(GO:0071564)
0.0 0.3 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.6 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.9 GO:0097440 apical dendrite(GO:0097440)
0.0 0.5 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 2.3 GO:0005814 centriole(GO:0005814)
0.0 3.8 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.7 GO:0016235 aggresome(GO:0016235)
0.0 4.5 GO:0043209 myelin sheath(GO:0043209)
0.0 0.4 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.2 GO:0043083 synaptic cleft(GO:0043083)
0.0 2.4 GO:0043204 perikaryon(GO:0043204)
0.0 2.3 GO:0008021 synaptic vesicle(GO:0008021)
0.0 0.5 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.7 GO:0031519 PcG protein complex(GO:0031519)
0.0 0.8 GO:0031941 filamentous actin(GO:0031941)
0.0 0.5 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 1.0 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 3.2 GO:0000151 ubiquitin ligase complex(GO:0000151)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 4.0 GO:0034012 glycerone kinase activity(GO:0004371) FAD-AMP lyase (cyclizing) activity(GO:0034012) triokinase activity(GO:0050354)
1.3 3.9 GO:0086057 voltage-gated calcium channel activity involved in bundle of His cell action potential(GO:0086057)
1.2 3.7 GO:0005353 fructose transmembrane transporter activity(GO:0005353) uniporter activity(GO:0015292)
1.0 2.9 GO:0004774 succinate-CoA ligase activity(GO:0004774)
0.8 2.5 GO:0030943 mitochondrion targeting sequence binding(GO:0030943)
0.6 3.2 GO:0047635 L-alanine:2-oxoglutarate aminotransferase activity(GO:0004021) alanine-oxo-acid transaminase activity(GO:0047635)
0.6 4.7 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.6 7.8 GO:0004000 adenosine deaminase activity(GO:0004000)
0.6 3.9 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.5 2.2 GO:0003918 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.5 1.5 GO:0001571 non-tyrosine kinase fibroblast growth factor receptor activity(GO:0001571)
0.4 1.2 GO:0004829 threonine-tRNA ligase activity(GO:0004829)
0.4 2.2 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.3 2.8 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.3 1.7 GO:2001070 starch binding(GO:2001070)
0.3 1.7 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.3 4.8 GO:0043495 protein anchor(GO:0043495)
0.3 1.9 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.3 2.1 GO:0070644 vitamin D response element binding(GO:0070644)
0.2 0.7 GO:0036009 protein-glutamine N-methyltransferase activity(GO:0036009) histone-glutamine methyltransferase activity(GO:1990259)
0.2 1.5 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
0.2 2.3 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.2 0.8 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.2 0.7 GO:0015157 sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.2 0.5 GO:0016419 [acyl-carrier-protein] S-malonyltransferase activity(GO:0004314) S-malonyltransferase activity(GO:0016419) malonyltransferase activity(GO:0016420)
0.2 2.6 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.1 1.2 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.1 1.7 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.1 1.5 GO:0048101 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1 2.5 GO:0048406 nerve growth factor binding(GO:0048406)
0.1 1.0 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.1 1.2 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.1 1.4 GO:0008494 translation activator activity(GO:0008494)
0.1 2.9 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.1 2.8 GO:0048018 receptor agonist activity(GO:0048018)
0.1 0.5 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.1 1.0 GO:0034511 U3 snoRNA binding(GO:0034511)
0.1 1.4 GO:0039706 co-receptor binding(GO:0039706)
0.1 0.8 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.1 0.4 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.1 0.4 GO:2001069 glycogen binding(GO:2001069)
0.1 1.0 GO:0043559 insulin binding(GO:0043559)
0.1 0.5 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.1 1.0 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.1 0.5 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.1 1.2 GO:0070097 delta-catenin binding(GO:0070097)
0.1 0.3 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.1 5.0 GO:0001786 phosphatidylserine binding(GO:0001786)
0.1 0.8 GO:0045504 dynein heavy chain binding(GO:0045504)
0.1 0.4 GO:0004594 pantothenate kinase activity(GO:0004594)
0.1 0.6 GO:0019158 fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.1 0.8 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.1 3.6 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.1 1.1 GO:0001972 retinoic acid binding(GO:0001972)
0.1 0.5 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.1 1.5 GO:0004385 guanylate kinase activity(GO:0004385)
0.1 1.8 GO:0000217 DNA secondary structure binding(GO:0000217)
0.1 1.4 GO:0008179 adenylate cyclase binding(GO:0008179)
0.1 0.5 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.1 1.8 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.1 0.7 GO:0001055 RNA polymerase I activity(GO:0001054) RNA polymerase II activity(GO:0001055)
0.1 0.5 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.1 2.0 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.1 0.5 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 0.4 GO:0051525 NFAT protein binding(GO:0051525)
0.0 2.0 GO:0045182 translation regulator activity(GO:0045182)
0.0 1.2 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.4 GO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282)
0.0 1.6 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.8 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.8 GO:0070411 I-SMAD binding(GO:0070411)
0.0 3.6 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.0 1.0 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 10.4 GO:0044325 ion channel binding(GO:0044325)
0.0 2.9 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 1.0 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.3 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.0 0.9 GO:0045499 chemorepellent activity(GO:0045499)
0.0 2.4 GO:0033613 activating transcription factor binding(GO:0033613)
0.0 0.3 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.0 0.1 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.0 0.3 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 3.0 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 0.7 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 1.8 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 1.4 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.6 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.4 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 11.7 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 1.2 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 3.7 GO:0030674 protein binding, bridging(GO:0030674)
0.0 0.1 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.0 0.6 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.8 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 2.0 GO:0051087 chaperone binding(GO:0051087)
0.0 0.5 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 1.9 GO:0051117 ATPase binding(GO:0051117)
0.0 0.9 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 0.3 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.4 GO:0003684 damaged DNA binding(GO:0003684)
0.0 2.0 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 2.0 GO:0005178 integrin binding(GO:0005178)
0.0 0.3 GO:0031005 filamin binding(GO:0031005)
0.0 0.5 GO:0001190 transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.0 0.8 GO:0043022 ribosome binding(GO:0043022)
0.0 2.7 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.9 GO:0004536 deoxyribonuclease activity(GO:0004536)
0.0 1.0 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.6 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.1 0.8 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.1 1.6 PID LPA4 PATHWAY LPA4-mediated signaling events
0.1 2.1 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.9 PID ATM PATHWAY ATM pathway
0.0 0.9 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 1.0 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 2.4 ST GA13 PATHWAY G alpha 13 Pathway
0.0 0.9 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 1.4 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 0.7 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 1.5 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 1.9 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 1.9 PID LKB1 PATHWAY LKB1 signaling events
0.0 2.2 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.5 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.8 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.4 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 0.6 PID IL3 PATHWAY IL3-mediated signaling events
0.0 0.3 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.6 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 4.0 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.2 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.4 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.7 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.1 2.7 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.1 2.9 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.1 2.9 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.1 3.2 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.1 3.9 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.1 2.9 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.1 2.2 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1 2.3 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.1 0.8 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 4.4 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.1 2.1 REACTOME REGULATORY RNA PATHWAYS Genes involved in Regulatory RNA pathways
0.1 1.1 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.1 1.8 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.1 2.0 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.1 0.7 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.1 1.4 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 1.7 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.8 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.0 1.4 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 1.8 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 0.7 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.7 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.6 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.0 0.7 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.0 0.6 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.4 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.9 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.0 0.5 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 1.4 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.5 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 1.8 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.3 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.5 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 1.0 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.0 0.6 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.5 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis