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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Tfap4

Z-value: 1.65

Motif logo

Transcription factors associated with Tfap4

Gene Symbol Gene ID Gene Info
ENSMUSG00000005718.9 Tfap4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Tfap4mm39_v1_chr16_-_4377640_4377718-0.226.1e-02Click!

Activity profile of Tfap4 motif

Sorted Z-values of Tfap4 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Tfap4

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr6_-_58884038 14.44 ENSMUST00000059539.5
nucleosome assembly protein 1-like 5
chr7_-_119801327 14.15 ENSMUST00000033198.6
crystallin, mu
chr10_+_127337541 11.53 ENSMUST00000160019.8
ENSMUST00000160610.2
ENSMUST00000035839.3
SH3 and cysteine rich domain 3
chr18_+_82572595 10.92 ENSMUST00000152071.9
ENSMUST00000142850.9
ENSMUST00000080658.12
ENSMUST00000133193.9
ENSMUST00000123251.9
ENSMUST00000153478.9
ENSMUST00000075372.13
ENSMUST00000102812.12
ENSMUST00000062446.15
ENSMUST00000114674.11
ENSMUST00000132369.3
myelin basic protein
chr13_+_46571910 9.96 ENSMUST00000037923.5
RNA binding motif protein 24
chr6_+_107506678 9.74 ENSMUST00000049285.10
leucine rich repeat protein 1, neuronal
chr6_-_36787096 9.59 ENSMUST00000201321.2
ENSMUST00000101534.5
pleiotrophin
chr15_-_99425555 9.54 ENSMUST00000231171.2
Fas apoptotic inhibitory molecule 2
chr8_+_13034245 8.12 ENSMUST00000110873.10
ENSMUST00000173006.8
ENSMUST00000145067.8
mcf.2 transforming sequence-like
chr7_-_126046814 7.96 ENSMUST00000146973.2
ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
chr2_+_97298002 7.56 ENSMUST00000059049.8
leucine rich repeat containing 4C
chr8_-_37200051 7.31 ENSMUST00000098826.10
deleted in liver cancer 1
chr11_+_102727122 7.11 ENSMUST00000021302.15
ENSMUST00000107072.2
HIG1 domain family, member 1B
chr9_+_75093177 7.06 ENSMUST00000129281.8
ENSMUST00000148144.8
ENSMUST00000130384.2
myosin VA
chr5_-_73805063 7.02 ENSMUST00000081170.9
sarcoglycan, beta (dystrophin-associated glycoprotein)
chr2_-_148574353 6.98 ENSMUST00000028926.13
N-ethylmaleimide sensitive fusion protein attachment protein beta
chr9_+_121606750 6.74 ENSMUST00000098272.4
kelch-like 40
chr6_-_115228800 6.73 ENSMUST00000205131.2
tissue inhibitor of metalloproteinase 4
chr13_+_93444514 6.72 ENSMUST00000079086.8
homer scaffolding protein 1
chr1_+_159351337 6.54 ENSMUST00000192069.6
tenascin R
chr2_-_80277969 6.44 ENSMUST00000028389.4
frizzled-related protein
chr12_+_88689638 6.39 ENSMUST00000190626.7
ENSMUST00000167103.8
neurexin III
chr6_-_54543446 6.39 ENSMUST00000019268.11
secernin 1
chr8_+_55003359 6.34 ENSMUST00000033918.4
ankyrin repeat and SOCs box-containing 5
chr2_-_92222979 6.29 ENSMUST00000111279.9
mitogen-activated protein kinase 8 interacting protein 1
chrX_+_100492684 6.27 ENSMUST00000033674.6
integrin beta 1 binding protein 2
chr13_+_55097200 5.98 ENSMUST00000026994.14
ENSMUST00000109994.9
unc-5 netrin receptor A
chr6_-_92458324 5.97 ENSMUST00000113445.2
prickle planar cell polarity protein 2
chr17_+_27171834 5.74 ENSMUST00000231853.2
synaptic Ras GTPase activating protein 1 homolog (rat)
chr1_-_165955445 5.72 ENSMUST00000085992.4
ENSMUST00000192369.6
dual specificity phosphatase 27 (putative)
chr19_-_40502117 5.64 ENSMUST00000225148.2
ENSMUST00000224667.2
ENSMUST00000225153.2
ENSMUST00000238831.2
ENSMUST00000226047.2
ENSMUST00000224247.2
sorbin and SH3 domain containing 1
chr2_-_52225146 5.58 ENSMUST00000075301.10
nebulin
chr9_-_79884920 5.55 ENSMUST00000239133.2
filamin A interacting protein 1
chr7_+_126811831 5.53 ENSMUST00000127710.3
myosin light chain, phosphorylatable, fast skeletal muscle
chr7_+_143838149 5.51 ENSMUST00000146006.3
SH3 and multiple ankyrin repeat domains 2
chr13_-_32967937 5.51 ENSMUST00000238977.3
myosin light chain kinase family, member 4
chr2_-_52225763 5.48 ENSMUST00000238288.2
ENSMUST00000238749.2
nebulin
chr19_-_5560473 5.48 ENSMUST00000237111.2
ENSMUST00000070172.6
sorting nexin 32
chr19_-_8816530 5.39 ENSMUST00000096259.6
guanine nucleotide binding protein (G protein), gamma 3
chr5_+_91665474 5.29 ENSMUST00000040576.10
prostate androgen-regulated mucin-like protein 1
chr9_-_79885063 5.24 ENSMUST00000093811.11
filamin A interacting protein 1
chr18_-_60724855 5.20 ENSMUST00000056533.9
myozenin 3
chr13_+_93441447 5.16 ENSMUST00000109497.8
ENSMUST00000109498.8
ENSMUST00000060490.11
ENSMUST00000109492.9
ENSMUST00000109496.8
ENSMUST00000109495.8
homer scaffolding protein 1
chr11_-_68762664 5.10 ENSMUST00000101017.9
nudE neurodevelopment protein 1 like 1
chr1_+_171077984 5.03 ENSMUST00000111315.9
ENSMUST00000219033.2
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 4
chr5_-_103174794 5.00 ENSMUST00000128869.8
mitogen-activated protein kinase 10
chr3_+_84832783 4.97 ENSMUST00000107675.8
F-box and WD-40 domain protein 7
chr3_-_108062172 4.92 ENSMUST00000062028.8
G protein-coupled receptor 61
chr8_+_55024446 4.83 ENSMUST00000239166.2
ENSMUST00000239106.2
ENSMUST00000239152.2
ankyrin repeat and SOCs box-containing 5
chr18_-_89787603 4.82 ENSMUST00000097495.5
docking protein 6
chr7_+_4925781 4.74 ENSMUST00000207527.2
ENSMUST00000207687.2
ENSMUST00000208754.2
N-acetyltransferase 14
chr2_-_74409225 4.70 ENSMUST00000134168.2
ENSMUST00000111993.9
ENSMUST00000064503.13
lunapark, ER junction formation factor
chr2_+_155224105 4.69 ENSMUST00000134218.2
transformation related protein 53 inducible nuclear protein 2
chr5_+_14564932 4.68 ENSMUST00000182407.8
ENSMUST00000030691.17
piccolo (presynaptic cytomatrix protein)
chr11_+_110858842 4.67 ENSMUST00000180023.8
ENSMUST00000106636.8
potassium inwardly-rectifying channel, subfamily J, member 16
chr6_+_112436466 4.63 ENSMUST00000075477.8
caveolin 3
chr8_-_71257623 4.61 ENSMUST00000212875.2
ENSMUST00000212001.2
ENSMUST00000212757.2
microtubule associated serine/threonine kinase 3
chr14_+_123897383 4.60 ENSMUST00000049681.14
integrin, beta-like 1
chr1_-_97904958 4.60 ENSMUST00000161567.8
peptidylglycine alpha-amidating monooxygenase
chr16_-_84970617 4.56 ENSMUST00000226232.2
ENSMUST00000227021.2
ENSMUST00000005406.12
ENSMUST00000227723.2
amyloid beta (A4) precursor protein
chr3_-_84128160 4.53 ENSMUST00000154152.2
ENSMUST00000107693.9
ENSMUST00000107695.9
tripartite motif-containing 2
chr16_+_20408886 4.53 ENSMUST00000232279.2
ENSMUST00000232474.2
von Willebrand factor A domain containing 5B2
chr13_-_8921732 4.42 ENSMUST00000054251.13
ENSMUST00000176813.8
ENSMUST00000175958.2
WD repeat domain 37
chr17_-_43813664 4.42 ENSMUST00000024707.9
ENSMUST00000117137.8
meprin 1 alpha
chr2_-_74409723 4.29 ENSMUST00000130586.8
lunapark, ER junction formation factor
chr14_+_70768257 4.26 ENSMUST00000047331.8
leucine-rich repeat LGI family, member 3
chr1_-_14380418 4.25 ENSMUST00000027066.13
ENSMUST00000168081.9
EYA transcriptional coactivator and phosphatase 1
chr9_-_119038162 4.20 ENSMUST00000084797.6
solute carrier family 22 (organic cation transporter), member 13
chr9_+_121539395 4.19 ENSMUST00000035113.11
ENSMUST00000215966.2
ENSMUST00000215833.2
ENSMUST00000215104.2
SS18, nBAF chromatin remodeling complex subunit like 2
chrX_-_47123719 4.12 ENSMUST00000039026.8
apelin
chrX_+_168468186 4.11 ENSMUST00000112107.8
ENSMUST00000112104.8
midline 1
chr7_+_107166653 4.09 ENSMUST00000120990.2
olfactomedin-like 1
chr5_-_147662798 4.09 ENSMUST00000110529.6
ENSMUST00000031653.12
FMS-like tyrosine kinase 1
chr15_-_102630496 4.03 ENSMUST00000171838.2
calcium binding and coiled coil domain 1
chr9_-_121621544 4.00 ENSMUST00000035110.11
hedgehog acyltransferase-like
chrX_+_55825033 3.99 ENSMUST00000114772.9
ENSMUST00000114768.10
ENSMUST00000155882.8
four and a half LIM domains 1
chr2_+_121125918 3.98 ENSMUST00000110639.8
microtubule-associated protein 1 A
chr12_-_78908409 3.95 ENSMUST00000021536.9
ATPase, H+ transporting, lysosomal V1 subunit D
chr18_+_57601541 3.92 ENSMUST00000091892.4
ENSMUST00000209782.2
cortexin 3
chr18_+_38429792 3.86 ENSMUST00000237211.2
ring finger protein 14
chr7_+_143838191 3.84 ENSMUST00000097929.4
SH3 and multiple ankyrin repeat domains 2
chr18_+_38430205 3.84 ENSMUST00000235491.2
ring finger protein 14
chr2_+_170573727 3.82 ENSMUST00000029075.5
docking protein 5
chr8_-_47742429 3.82 ENSMUST00000079195.6
storkhead box 2
chr6_+_126916919 3.81 ENSMUST00000032497.7
DNA segment, Chr 6, Wayne State University 163, expressed
chr2_+_155223728 3.81 ENSMUST00000043237.14
ENSMUST00000174685.8
transformation related protein 53 inducible nuclear protein 2
chr6_+_21215472 3.76 ENSMUST00000081542.6
potassium voltage-gated channel, Shal-related family, member 2
chr14_+_67470884 3.72 ENSMUST00000176161.8
early B cell factor 2
chr7_-_141015240 3.70 ENSMUST00000138865.8
solute carrier family 25 (mitochondrial carrier, glutamate), member 22
chr10_+_24025188 3.67 ENSMUST00000020174.7
ENSMUST00000220041.2
syntaxin 7
chr5_-_116221293 3.67 ENSMUST00000111997.3
ENSMUST00000239438.2
transmembrane protein 233
chrX_+_55824797 3.64 ENSMUST00000114773.10
four and a half LIM domains 1
chr2_+_174602412 3.63 ENSMUST00000029030.9
endothelin 3
chr6_-_53797748 3.62 ENSMUST00000127748.5
TLR4 interactor with leucine-rich repeats
chr14_+_70768289 3.61 ENSMUST00000226548.2
leucine-rich repeat LGI family, member 3
chr10_-_102326286 3.61 ENSMUST00000020040.5
neurotensin
chr16_-_84970580 3.58 ENSMUST00000227737.2
ENSMUST00000226801.2
amyloid beta (A4) precursor protein
chr19_+_34585322 3.51 ENSMUST00000076249.6
interferon-induced protein with tetratricopeptide repeats 3B
chr1_-_14380327 3.51 ENSMUST00000080664.14
EYA transcriptional coactivator and phosphatase 1
chr11_-_107607343 3.46 ENSMUST00000021065.6
calcium channel, voltage-dependent, gamma subunit 1
chr8_-_84299540 3.46 ENSMUST00000212990.2
trans-2,3-enoyl-CoA reductase
chr11_+_109376432 3.45 ENSMUST00000106697.8
arylsulfatase G
chr13_-_47168286 3.45 ENSMUST00000052747.4
NHL repeat containing 1
chr5_+_31274064 3.44 ENSMUST00000202769.2
tripartite motif-containing 54
chr2_-_73410632 3.43 ENSMUST00000028515.4
cholinergic receptor, nicotinic, alpha polypeptide 1 (muscle)
chr10_+_69816153 3.41 ENSMUST00000182207.8
ankyrin 3, epithelial
chr8_+_15107646 3.37 ENSMUST00000033842.4
myomesin 2
chr1_+_128069677 3.34 ENSMUST00000187023.7
R3H domain containing 1
chr14_-_45456821 3.32 ENSMUST00000128484.8
ENSMUST00000147853.8
ENSMUST00000022377.11
ENSMUST00000143609.2
ENSMUST00000153383.8
ENSMUST00000139526.9
thioredoxin domain containing 16
chr11_+_102159558 3.32 ENSMUST00000036467.5
ankyrin repeat and SOCS box-containing 16
chr3_-_116047148 3.31 ENSMUST00000090473.7
G-protein coupled receptor 88
chr5_+_134128543 3.31 ENSMUST00000016088.9
cytosolic arginine sensor for mTORC1 subunit 2
chr6_+_126916956 3.29 ENSMUST00000201617.2
DNA segment, Chr 6, Wayne State University 163, expressed
chr2_+_106523532 3.28 ENSMUST00000111063.8
metallophosphoesterase domain containing 2
chr16_-_89615225 3.27 ENSMUST00000164263.9
T cell lymphoma invasion and metastasis 1
chr8_-_84299850 3.19 ENSMUST00000212703.2
trans-2,3-enoyl-CoA reductase
chr8_+_66838927 3.19 ENSMUST00000039540.12
ENSMUST00000110253.3
membrane associated ring-CH-type finger 1
chr18_+_38429688 3.19 ENSMUST00000170811.8
ENSMUST00000072376.13
ENSMUST00000237903.2
ENSMUST00000236116.2
ENSMUST00000237824.2
ENSMUST00000236982.2
ENSMUST00000235549.2
ENSMUST00000237416.2
ENSMUST00000237089.2
ring finger protein 14
chr18_-_39062201 3.13 ENSMUST00000134864.2
fibroblast growth factor 1
chr4_-_134431534 3.13 ENSMUST00000054096.13
ENSMUST00000038628.4
mannosidase, alpha, class 1C, member 1
chr5_+_102872838 3.12 ENSMUST00000112853.8
Rho GTPase activating protein 24
chr8_-_106198112 3.09 ENSMUST00000014990.13
tubulin polymerization-promoting protein family member 3
chr10_+_80136830 3.09 ENSMUST00000140828.8
ENSMUST00000138909.8
APC regulator of WNT signaling pathway 2
chr5_+_31274046 3.06 ENSMUST00000013771.15
tripartite motif-containing 54
chr9_-_40257586 3.03 ENSMUST00000121357.8
GRAM domain containing 1B
chr16_-_88087087 3.03 ENSMUST00000211444.2
ENSMUST00000023652.16
ENSMUST00000072256.13
glutamate receptor, ionotropic, kainate 1
chr19_+_34560922 3.02 ENSMUST00000102825.4
interferon-induced protein with tetratricopeptide repeats 3
chr1_-_80642969 3.01 ENSMUST00000190983.7
ENSMUST00000191449.2
dedicator of cytokinesis 10
chr7_-_97066937 3.00 ENSMUST00000043077.8
thyroid hormone responsive
chrX_-_141089165 2.98 ENSMUST00000134825.3
potassium voltage-gated channel, Isk-related family, member 1-like, pseudogene
chr14_+_3575406 2.97 ENSMUST00000124353.2
ubiquitin-conjugating enzyme E2E 2
chr18_+_38429858 2.94 ENSMUST00000171461.3
ENSMUST00000235811.2
ring finger protein 14
chr9_-_44162762 2.91 ENSMUST00000034618.6
PDZ domain containing 3
chr6_+_47021979 2.89 ENSMUST00000150737.2
contactin associated protein-like 2
chr5_-_146521629 2.89 ENSMUST00000200112.2
ENSMUST00000197431.2
ENSMUST00000197825.2
G-protein coupled receptor 12
chr10_+_39296005 2.87 ENSMUST00000157009.8
Fyn proto-oncogene
chr3_+_90444537 2.86 ENSMUST00000098911.10
S100 calcium binding protein A16
chr1_-_25267894 2.83 ENSMUST00000126626.8
adhesion G protein-coupled receptor B3
chr8_+_45960931 2.82 ENSMUST00000171337.10
ENSMUST00000067107.15
sorbin and SH3 domain containing 2
chr15_-_76906832 2.81 ENSMUST00000019037.10
ENSMUST00000169226.9
myoglobin
chr14_+_54496683 2.76 ENSMUST00000041197.13
ENSMUST00000239403.2
ENSMUST00000197605.3
abhydrolase domain containing 4
chr17_+_14087827 2.75 ENSMUST00000239324.2
afadin, adherens junction formation factor
chr11_-_12362136 2.75 ENSMUST00000174874.8
cordon-bleu WH2 repeat
chr13_+_64309675 2.70 ENSMUST00000021929.10
hyaluronic acid binding protein 4
chr19_+_45035942 2.67 ENSMUST00000237222.2
ENSMUST00000111954.11
sideroflexin 3
chr11_+_68582923 2.65 ENSMUST00000018887.15
myosin, heavy polypeptide 10, non-muscle
chr5_-_137246852 2.65 ENSMUST00000179412.2
mucin 3A, cell surface associated
chr5_+_28047147 2.63 ENSMUST00000036227.7
5-hydroxytryptamine (serotonin) receptor 5A
chr11_+_68582897 2.62 ENSMUST00000108673.8
myosin, heavy polypeptide 10, non-muscle
chr6_+_34840057 2.60 ENSMUST00000074949.4
transmembrane protein 140
chr8_+_123912976 2.58 ENSMUST00000019422.6
dipeptidase 1
chr6_+_90442269 2.58 ENSMUST00000113530.4
Kruppel-like factor 15
chr7_-_4517559 2.57 ENSMUST00000163538.8
troponin T1, skeletal, slow
chr7_+_105290259 2.55 ENSMUST00000209445.2
translocase of inner mitochondrial membrane 10B
chr16_+_48662894 2.55 ENSMUST00000238847.2
ENSMUST00000023329.7
resistin like alpha
chr8_+_84699580 2.54 ENSMUST00000005606.8
protein kinase, cAMP dependent, catalytic, alpha
chr18_+_38430015 2.53 ENSMUST00000236319.2
ring finger protein 14
chr15_-_102630589 2.51 ENSMUST00000023818.11
calcium binding and coiled coil domain 1
chr8_+_83891972 2.49 ENSMUST00000034145.11
TBC1 domain family, member 9
chr16_+_16844217 2.45 ENSMUST00000232067.2
mitogen-activated protein kinase 1
chr4_-_43040278 2.40 ENSMUST00000107958.8
ENSMUST00000107959.8
ENSMUST00000152846.8
family with sequence similarity 214, member B
chr6_-_131655849 2.40 ENSMUST00000076756.3
taste receptor, type 2, member 106
chr14_+_67470735 2.40 ENSMUST00000022637.14
early B cell factor 2
chr5_-_131567526 2.40 ENSMUST00000161374.8
autism susceptibility candidate 2
chr3_-_89230190 2.38 ENSMUST00000200436.2
ENSMUST00000029673.10
ephrin A3
chr15_+_38662158 2.37 ENSMUST00000022904.8
ENSMUST00000228820.2
ATPase, H+ transporting, lysosomal V1 subunit C1
chr10_-_7539333 2.30 ENSMUST00000162606.8
protein-L-isoaspartate (D-aspartate) O-methyltransferase 1
chr5_-_137246611 2.27 ENSMUST00000196391.5
mucin 3A, cell surface associated
chrX_+_92718695 2.25 ENSMUST00000045898.4
phosphate cytidylyltransferase 1, choline, beta isoform
chr11_+_110858882 2.23 ENSMUST00000125692.2
potassium inwardly-rectifying channel, subfamily J, member 16
chr9_-_50605079 2.22 ENSMUST00000120622.2
DIX domain containing 1
chr14_+_20757615 2.19 ENSMUST00000022358.9
ENSMUST00000224751.2
zinc finger SWIM-type containing 8
chrX_+_139565657 2.18 ENSMUST00000112990.8
ENSMUST00000112988.8
midline 2
chr7_+_15832383 2.18 ENSMUST00000006181.7
N-ethylmaleimide sensitive fusion protein attachment protein alpha
chr15_-_97665524 2.15 ENSMUST00000128775.9
ENSMUST00000134885.3
Rap guanine nucleotide exchange factor (GEF) 3
chr11_+_97253221 2.14 ENSMUST00000238729.2
ENSMUST00000045540.4
suppressor of cytokine signaling 7
chr1_-_80643024 2.12 ENSMUST00000187774.7
dedicator of cytokinesis 10
chr2_-_104542467 2.11 ENSMUST00000111118.8
ENSMUST00000028597.4
t-complex 11 like 1
chr3_-_51468236 2.10 ENSMUST00000037141.9
SET domain containing (lysine methyltransferase) 7
chr6_+_8259405 2.09 ENSMUST00000160705.8
ENSMUST00000159433.8
UMAP1-MVP12 associated (UMA) domain containing 1
chr5_+_117495337 2.07 ENSMUST00000031309.16
WD repeat and SOCS box-containing 2
chr6_+_34840151 2.07 ENSMUST00000202010.2
transmembrane protein 140
chr15_+_80171435 2.07 ENSMUST00000160424.8
calcium channel, voltage-dependent, alpha 1I subunit
chr8_-_47742389 2.06 ENSMUST00000211737.2
storkhead box 2
chr4_+_118522716 2.05 ENSMUST00000102666.5
olfactory receptor 62
chrX_+_133305529 2.04 ENSMUST00000113224.9
ENSMUST00000113226.2
dystrophin related protein 2
chr5_-_69499014 1.90 ENSMUST00000087231.4
ENSMUST00000054095.6
potassium channel tetramerisation domain containing 8
chr1_+_187730032 1.90 ENSMUST00000110938.2
estrogen-related receptor gamma
chr15_-_97665679 1.90 ENSMUST00000129223.9
ENSMUST00000126854.9
ENSMUST00000135080.2
Rap guanine nucleotide exchange factor (GEF) 3
chrX_+_9751861 1.89 ENSMUST00000067529.9
ENSMUST00000086165.4
synaptotagmin-like 5
chr1_-_162485675 1.89 ENSMUST00000193898.2
ENSMUST00000169439.3
myocilin opposite strand
chr7_-_4517608 1.88 ENSMUST00000166959.8
troponin T1, skeletal, slow
chr18_+_73996743 1.88 ENSMUST00000134847.2
maestro
chr15_-_75620060 1.84 ENSMUST00000062002.6
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein A (avian)
chr4_+_152270636 1.82 ENSMUST00000030779.10
acyl-CoA thioesterase 7
chr8_+_75760301 1.82 ENSMUST00000165630.3
ENSMUST00000212651.2
ENSMUST00000212388.2
ENSMUST00000212299.2
ENSMUST00000078847.13
ENSMUST00000211869.2
target of myb1 trafficking protein
chr3_+_90444613 1.80 ENSMUST00000107335.2
S100 calcium binding protein A16
chr8_+_3550450 1.79 ENSMUST00000004683.13
ENSMUST00000160338.2
mucolipin 1
chr10_+_60113449 1.79 ENSMUST00000105465.8
ENSMUST00000179238.8
ENSMUST00000177779.8
ENSMUST00000004316.15
prosaposin
chr4_+_48045143 1.77 ENSMUST00000030025.10
nuclear receptor subfamily 4, group A, member 3

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.7 10.9 GO:1904209 regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
2.7 8.1 GO:0051563 smooth endoplasmic reticulum calcium ion homeostasis(GO:0051563) cellular response to norepinephrine stimulus(GO:0071874)
2.7 8.0 GO:0051659 maintenance of mitochondrion location(GO:0051659) relaxation of skeletal muscle(GO:0090076)
2.4 9.6 GO:1904395 positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395)
1.8 14.1 GO:0070327 thyroid hormone transport(GO:0070327)
1.6 11.3 GO:0007258 JUN phosphorylation(GO:0007258)
1.6 4.7 GO:0098928 presynaptic signal transduction(GO:0098928) presynapse to nucleus signaling pathway(GO:0099526)
1.4 7.1 GO:0051643 endoplasmic reticulum localization(GO:0051643)
1.4 4.1 GO:1904020 regulation of G-protein coupled receptor internalization(GO:1904020)
1.3 4.0 GO:0006500 N-terminal protein palmitoylation(GO:0006500)
1.3 5.3 GO:0070650 actin filament bundle distribution(GO:0070650)
1.3 6.4 GO:0070366 regulation of hepatocyte differentiation(GO:0070366)
1.2 6.0 GO:0001830 trophectodermal cell fate commitment(GO:0001830)
1.1 6.5 GO:0048686 regulation of sprouting of injured axon(GO:0048686) regulation of axon extension involved in regeneration(GO:0048690)
1.1 3.3 GO:1904268 regulation of Schwann cell chemotaxis(GO:1904266) positive regulation of Schwann cell chemotaxis(GO:1904268) Schwann cell chemotaxis(GO:1990751)
1.1 3.2 GO:0006434 seryl-tRNA aminoacylation(GO:0006434)
1.0 4.0 GO:1904453 regulation of hydrogen:potassium-exchanging ATPase activity(GO:1904451) positive regulation of hydrogen:potassium-exchanging ATPase activity(GO:1904453)
1.0 9.0 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
1.0 5.0 GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
1.0 6.7 GO:0098528 skeletal muscle fiber differentiation(GO:0098528)
0.9 3.7 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.9 2.6 GO:0070676 intralumenal vesicle formation(GO:0070676) negative regulation of early endosome to late endosome transport(GO:2000642)
0.9 6.1 GO:0061743 motor learning(GO:0061743)
0.9 5.2 GO:0003100 regulation of systemic arterial blood pressure by endothelin(GO:0003100) vein smooth muscle contraction(GO:0014826)
0.9 2.6 GO:0016999 antibiotic metabolic process(GO:0016999)
0.8 9.0 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.8 4.7 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.7 5.4 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.7 4.6 GO:1904180 negative regulation of membrane depolarization(GO:1904180)
0.7 9.2 GO:0010807 regulation of synaptic vesicle priming(GO:0010807)
0.6 2.4 GO:0019858 cytosine metabolic process(GO:0019858)
0.6 2.4 GO:0098582 innate vocalization behavior(GO:0098582)
0.6 11.9 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.6 4.6 GO:0031179 peptide modification(GO:0031179)
0.5 0.5 GO:2000974 negative regulation of pro-B cell differentiation(GO:2000974)
0.5 6.0 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.5 2.7 GO:0036115 fatty-acyl-CoA catabolic process(GO:0036115)
0.5 2.6 GO:0007198 adenylate cyclase-inhibiting serotonin receptor signaling pathway(GO:0007198)
0.5 4.1 GO:0048597 post-embryonic camera-type eye morphogenesis(GO:0048597)
0.5 5.1 GO:0051081 membrane disassembly(GO:0030397) positive regulation of axon regeneration(GO:0048680) nuclear envelope disassembly(GO:0051081)
0.5 6.8 GO:0035372 protein localization to microtubule(GO:0035372)
0.5 7.0 GO:0097084 vascular smooth muscle cell development(GO:0097084)
0.5 2.7 GO:0034334 adherens junction maintenance(GO:0034334)
0.5 9.5 GO:0021702 cerebellar Purkinje cell differentiation(GO:0021702)
0.5 1.4 GO:0003032 detection of oxygen(GO:0003032)
0.4 3.1 GO:1901509 regulation of endothelial tube morphogenesis(GO:1901509)
0.4 1.8 GO:1900625 positive regulation of mast cell cytokine production(GO:0032765) regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.4 2.9 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.4 7.3 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.4 2.7 GO:0001757 somite specification(GO:0001757)
0.4 3.0 GO:0014054 positive regulation of gamma-aminobutyric acid secretion(GO:0014054)
0.4 1.5 GO:1903923 renal protein absorption(GO:0097017) protein processing in phagocytic vesicle(GO:1900756) positive regulation of keratinocyte apoptotic process(GO:1902174) regulation of protein processing in phagocytic vesicle(GO:1903921) positive regulation of protein processing in phagocytic vesicle(GO:1903923)
0.4 1.1 GO:0048003 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.3 16.4 GO:0060765 regulation of androgen receptor signaling pathway(GO:0060765)
0.3 3.8 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.3 2.2 GO:0019660 glucose catabolic process to lactate(GO:0019659) glycolytic fermentation(GO:0019660) glucose catabolic process to lactate via pyruvate(GO:0019661)
0.3 2.8 GO:0015671 oxygen transport(GO:0015671)
0.3 3.1 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.3 11.1 GO:0071625 vocalization behavior(GO:0071625)
0.3 0.9 GO:0014908 myotube differentiation involved in skeletal muscle regeneration(GO:0014908)
0.3 4.4 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.3 2.9 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.3 11.6 GO:0003009 skeletal muscle contraction(GO:0003009)
0.3 0.9 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.3 3.1 GO:0006013 mannose metabolic process(GO:0006013)
0.3 4.2 GO:0015747 urate transport(GO:0015747)
0.3 3.0 GO:0060372 regulation of atrial cardiac muscle cell membrane repolarization(GO:0060372)
0.3 1.6 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.3 6.7 GO:0042761 fatty acid elongation(GO:0030497) very long-chain fatty acid biosynthetic process(GO:0042761)
0.3 2.4 GO:1902961 positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902961) positive regulation of aspartic-type peptidase activity(GO:1905247)
0.3 2.1 GO:1902951 negative regulation of dendritic spine maintenance(GO:1902951)
0.3 1.3 GO:0019072 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.3 6.4 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.3 1.3 GO:0038032 termination of G-protein coupled receptor signaling pathway(GO:0038032)
0.2 1.2 GO:1904970 brush border assembly(GO:1904970)
0.2 6.1 GO:0035563 positive regulation of chromatin binding(GO:0035563)
0.2 3.8 GO:0046498 S-adenosylhomocysteine metabolic process(GO:0046498)
0.2 11.1 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.2 2.9 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.2 1.1 GO:0097309 cap1 mRNA methylation(GO:0097309)
0.2 1.2 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
0.2 3.4 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.2 2.5 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.2 3.8 GO:0051386 regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
0.2 8.1 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.2 2.2 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.2 17.1 GO:0030239 myofibril assembly(GO:0030239)
0.2 2.1 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.2 1.3 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.1 0.4 GO:0033577 protein glycosylation in endoplasmic reticulum(GO:0033577)
0.1 7.1 GO:0043304 regulation of mast cell activation involved in immune response(GO:0033006) regulation of mast cell degranulation(GO:0043304)
0.1 5.0 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.1 1.2 GO:0006561 proline biosynthetic process(GO:0006561)
0.1 12.0 GO:0006334 nucleosome assembly(GO:0006334)
0.1 5.7 GO:0048169 regulation of long-term neuronal synaptic plasticity(GO:0048169)
0.1 9.4 GO:0010830 regulation of myotube differentiation(GO:0010830)
0.1 0.4 GO:0019464 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.1 7.0 GO:0010972 negative regulation of G2/M transition of mitotic cell cycle(GO:0010972)
0.1 1.7 GO:0060363 cranial suture morphogenesis(GO:0060363)
0.1 2.1 GO:0021819 layer formation in cerebral cortex(GO:0021819)
0.1 3.7 GO:0015813 L-glutamate transport(GO:0015813)
0.1 3.8 GO:0045475 locomotor rhythm(GO:0045475)
0.1 1.8 GO:0007263 nitric oxide mediated signal transduction(GO:0007263)
0.1 1.8 GO:0060736 prostate gland growth(GO:0060736) epithelial cell differentiation involved in prostate gland development(GO:0060742)
0.1 3.4 GO:0045725 positive regulation of glycogen biosynthetic process(GO:0045725)
0.1 0.4 GO:0008050 female courtship behavior(GO:0008050)
0.1 4.0 GO:0034142 toll-like receptor 4 signaling pathway(GO:0034142)
0.1 1.5 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.1 2.6 GO:0003299 muscle hypertrophy in response to stress(GO:0003299) cardiac muscle adaptation(GO:0014887) cardiac muscle hypertrophy in response to stress(GO:0014898)
0.1 3.3 GO:0097352 autophagosome maturation(GO:0097352)
0.1 9.7 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.1 3.5 GO:0070296 sarcoplasmic reticulum calcium ion transport(GO:0070296)
0.1 0.5 GO:0007468 regulation of rhodopsin gene expression(GO:0007468)
0.1 2.7 GO:0071260 cellular response to mechanical stimulus(GO:0071260)
0.1 0.5 GO:1905146 lysosomal protein catabolic process(GO:1905146)
0.1 3.0 GO:0010866 regulation of triglyceride biosynthetic process(GO:0010866)
0.1 1.4 GO:0002026 regulation of the force of heart contraction(GO:0002026)
0.1 5.2 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.1 2.1 GO:0045956 positive regulation of calcium ion-dependent exocytosis(GO:0045956)
0.1 2.8 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.1 0.5 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.1 1.1 GO:0036295 cellular response to increased oxygen levels(GO:0036295) response to increased oxygen levels(GO:0036296)
0.1 4.0 GO:0061512 protein localization to cilium(GO:0061512)
0.1 2.4 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.1 0.5 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.1 1.8 GO:0035634 response to stilbenoid(GO:0035634)
0.1 0.7 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.1 9.8 GO:0017157 regulation of exocytosis(GO:0017157)
0.1 0.4 GO:0034134 toll-like receptor 2 signaling pathway(GO:0034134)
0.0 1.8 GO:0032418 lysosome localization(GO:0032418)
0.0 5.1 GO:0001578 microtubule bundle formation(GO:0001578)
0.0 1.4 GO:0046852 positive regulation of bone resorption(GO:0045780) positive regulation of bone remodeling(GO:0046852)
0.0 8.3 GO:0043401 steroid hormone mediated signaling pathway(GO:0043401)
0.0 0.5 GO:0046886 positive regulation of hormone biosynthetic process(GO:0046886)
0.0 0.7 GO:0016242 negative regulation of macroautophagy(GO:0016242)
0.0 1.1 GO:0030318 melanocyte differentiation(GO:0030318)
0.0 2.3 GO:0001541 ovarian follicle development(GO:0001541)
0.0 4.7 GO:0051592 response to calcium ion(GO:0051592)
0.0 3.3 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 2.1 GO:0016239 positive regulation of macroautophagy(GO:0016239)
0.0 1.7 GO:0010107 potassium ion import(GO:0010107)
0.0 5.5 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.0 0.2 GO:0014827 intestine smooth muscle contraction(GO:0014827)
0.0 2.2 GO:0008542 visual learning(GO:0008542)
0.0 0.9 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.9 GO:0046627 negative regulation of insulin receptor signaling pathway(GO:0046627)
0.0 0.4 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 0.2 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.0 0.4 GO:0046037 GMP metabolic process(GO:0046037)
0.0 1.8 GO:0000045 autophagosome assembly(GO:0000045)
0.0 0.5 GO:0021799 cerebral cortex radially oriented cell migration(GO:0021799)
0.0 0.1 GO:0015889 cobalamin transport(GO:0015889)
0.0 0.4 GO:0034389 lipid particle organization(GO:0034389)
0.0 1.9 GO:0008277 regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)
0.0 2.2 GO:0006887 exocytosis(GO:0006887)
0.0 0.4 GO:0007520 myoblast fusion(GO:0007520)
0.0 2.1 GO:0019236 response to pheromone(GO:0019236)
0.0 2.6 GO:1990823 response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)
0.0 0.3 GO:0036010 protein localization to endosome(GO:0036010)
0.0 0.4 GO:0043001 Golgi to plasma membrane protein transport(GO:0043001)
0.0 0.2 GO:0090140 regulation of mitochondrial fission(GO:0090140)
0.0 3.6 GO:0006874 cellular calcium ion homeostasis(GO:0006874)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 6.3 GO:0044302 dentate gyrus mossy fiber(GO:0044302)
1.8 7.1 GO:0042642 actomyosin, myosin complex part(GO:0042642)
1.6 6.5 GO:0072534 perineuronal net(GO:0072534)
1.6 4.7 GO:0044317 rod spherule(GO:0044317)
1.5 9.2 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
1.4 10.9 GO:0033269 internode region of axon(GO:0033269)
1.3 5.1 GO:0060053 neurofilament cytoskeleton(GO:0060053)
1.2 5.0 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
1.0 4.0 GO:1990795 lateral part of cell(GO:0097574) basolateral part of cell(GO:1990794) rod bipolar cell terminal bouton(GO:1990795)
1.0 8.0 GO:0031673 H zone(GO:0031673)
0.9 5.6 GO:0005899 insulin receptor complex(GO:0005899)
0.8 7.0 GO:0016012 sarcoglycan complex(GO:0016012)
0.8 5.3 GO:0097513 myosin II filament(GO:0097513)
0.7 8.1 GO:1990812 growth cone lamellipodium(GO:1990761) growth cone filopodium(GO:1990812)
0.7 9.4 GO:0005883 neurofilament(GO:0005883)
0.6 2.4 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.5 3.7 GO:0070820 tertiary granule(GO:0070820)
0.5 4.4 GO:0070545 PeBoW complex(GO:0070545)
0.5 3.6 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.4 2.6 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.4 3.0 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.4 1.1 GO:0098830 presynaptic endosome(GO:0098830)
0.3 2.7 GO:1990357 terminal web(GO:1990357)
0.3 4.6 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.3 0.8 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.3 15.0 GO:0043034 costamere(GO:0043034)
0.3 5.7 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.2 4.7 GO:0005861 troponin complex(GO:0005861)
0.2 3.1 GO:0097427 microtubule bundle(GO:0097427)
0.2 9.1 GO:0005865 striated muscle thin filament(GO:0005865)
0.2 3.3 GO:0060091 kinocilium(GO:0060091)
0.2 12.9 GO:0031672 A band(GO:0031672)
0.2 1.7 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.2 6.0 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.2 9.7 GO:0032809 neuronal cell body membrane(GO:0032809)
0.2 0.9 GO:1990745 GARP complex(GO:0000938) EARP complex(GO:1990745)
0.2 3.1 GO:0031258 lamellipodium membrane(GO:0031258)
0.2 2.6 GO:0032009 early phagosome(GO:0032009)
0.2 15.6 GO:0031594 neuromuscular junction(GO:0031594)
0.2 1.3 GO:0033263 CORVET complex(GO:0033263)
0.2 3.0 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.1 1.5 GO:0030478 actin cap(GO:0030478)
0.1 2.4 GO:0031143 pseudopodium(GO:0031143)
0.1 2.1 GO:0043083 synaptic cleft(GO:0043083)
0.1 2.2 GO:0035686 sperm fibrous sheath(GO:0035686)
0.1 2.9 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.1 6.3 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 0.6 GO:0031429 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.1 11.0 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.1 15.8 GO:0030017 sarcomere(GO:0030017)
0.1 7.3 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.1 6.4 GO:0042734 presynaptic membrane(GO:0042734)
0.1 1.5 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.1 3.5 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.1 9.7 GO:0043204 perikaryon(GO:0043204)
0.1 3.3 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.1 0.4 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.1 0.5 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.1 5.8 GO:0043679 axon terminus(GO:0043679)
0.1 4.1 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 13.1 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 10.9 GO:0070382 exocytic vesicle(GO:0070382)
0.0 9.0 GO:0032993 protein-DNA complex(GO:0032993)
0.0 0.7 GO:0044754 autolysosome(GO:0044754)
0.0 1.3 GO:0097440 apical dendrite(GO:0097440)
0.0 16.8 GO:0000151 ubiquitin ligase complex(GO:0000151)
0.0 0.4 GO:0032590 dendrite membrane(GO:0032590)
0.0 6.8 GO:0099572 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.0 3.0 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 9.1 GO:0005765 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 3.5 GO:0043197 dendritic spine(GO:0043197)
0.0 16.7 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 7.1 GO:0031225 anchored component of membrane(GO:0031225)
0.0 5.3 GO:0005770 late endosome(GO:0005770)
0.0 0.8 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 2.7 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 9.8 GO:0005924 cell-substrate adherens junction(GO:0005924) focal adhesion(GO:0005925)
0.0 1.4 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.8 GO:0005581 collagen trimer(GO:0005581)
0.0 0.6 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 2.8 GO:0005875 microtubule associated complex(GO:0005875)
0.0 4.0 GO:0000323 lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.0 0.2 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.7 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 2.2 GO:0005769 early endosome(GO:0005769)
0.0 5.7 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 1.5 GO:0005903 brush border(GO:0005903)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.4 9.6 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
1.8 9.2 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
1.3 5.2 GO:0031708 endothelin B receptor binding(GO:0031708)
1.1 4.6 GO:0016842 amidine-lyase activity(GO:0016842)
1.1 14.7 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
1.1 3.2 GO:0004828 serine-tRNA ligase activity(GO:0004828)
1.0 5.2 GO:0051373 FATZ binding(GO:0051373)
1.0 5.1 GO:0070012 oligopeptidase activity(GO:0070012)
1.0 8.1 GO:0051425 PTB domain binding(GO:0051425)
1.0 14.1 GO:0070324 thyroid hormone binding(GO:0070324)
1.0 5.0 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.9 5.4 GO:0042296 ISG15 transferase activity(GO:0042296)
0.8 5.0 GO:0050816 phosphothreonine binding(GO:0050816)
0.8 3.8 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.8 3.8 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.7 6.0 GO:0005042 netrin receptor activity(GO:0005042)
0.7 10.9 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.6 5.5 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.6 8.0 GO:0005338 nucleotide-sugar transmembrane transporter activity(GO:0005338)
0.6 4.1 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.6 2.3 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.5 2.6 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.5 2.1 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.5 3.0 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.5 1.5 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.5 4.7 GO:0031014 troponin T binding(GO:0031014)
0.4 2.9 GO:0030249 guanylate cyclase regulator activity(GO:0030249)
0.4 7.1 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.4 9.0 GO:0016805 dipeptidase activity(GO:0016805)
0.4 1.5 GO:0045159 myosin II binding(GO:0045159)
0.4 6.5 GO:0046625 sphingolipid binding(GO:0046625)
0.4 2.5 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.4 4.6 GO:0071253 connexin binding(GO:0071253)
0.3 6.3 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.3 1.3 GO:0004736 pyruvate carboxylase activity(GO:0004736)
0.3 2.8 GO:0005344 oxygen transporter activity(GO:0005344)
0.3 4.0 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.3 6.7 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.3 16.7 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.3 1.2 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.3 6.5 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.3 2.1 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.3 3.7 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.3 4.7 GO:0005522 profilin binding(GO:0005522)
0.3 6.4 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.2 3.1 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.2 0.9 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
0.2 1.2 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.2 3.7 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.2 4.6 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.2 6.9 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.2 2.7 GO:0030274 LIM domain binding(GO:0030274)
0.2 1.4 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.2 3.0 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.2 5.3 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.2 7.3 GO:0017166 vinculin binding(GO:0017166)
0.2 2.8 GO:0051378 serotonin binding(GO:0051378)
0.2 2.2 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.2 3.5 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.2 13.0 GO:0005158 insulin receptor binding(GO:0005158)
0.2 3.9 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.2 1.6 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.2 1.1 GO:0004483 mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483)
0.2 3.6 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.2 1.2 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.2 1.8 GO:0004565 beta-galactosidase activity(GO:0004565)
0.2 3.4 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.2 3.1 GO:0044548 S100 protein binding(GO:0044548)
0.1 4.7 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.1 1.8 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.1 8.6 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.1 2.4 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.1 6.4 GO:0005246 calcium channel regulator activity(GO:0005246)
0.1 2.4 GO:0033038 bitter taste receptor activity(GO:0033038)
0.1 3.9 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.1 0.6 GO:0002046 opsin binding(GO:0002046)
0.1 3.6 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.1 0.4 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
0.1 5.5 GO:0003785 actin monomer binding(GO:0003785)
0.1 3.6 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.1 2.7 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 4.2 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.1 5.6 GO:0046875 ephrin receptor binding(GO:0046875)
0.1 0.6 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.1 5.2 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.1 9.0 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.1 6.7 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors(GO:0016627)
0.1 10.0 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.1 3.6 GO:0008307 structural constituent of muscle(GO:0008307)
0.1 9.7 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.1 0.6 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.1 9.0 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 0.6 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.1 9.8 GO:0043130 ubiquitin binding(GO:0043130)
0.1 3.5 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.1 1.9 GO:0070001 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.1 10.1 GO:0017124 SH3 domain binding(GO:0017124)
0.1 0.6 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 4.3 GO:0005518 collagen binding(GO:0005518)
0.0 1.6 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.5 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 3.7 GO:0030276 clathrin binding(GO:0030276)
0.0 4.9 GO:0051219 phosphoprotein binding(GO:0051219)
0.0 0.4 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 2.8 GO:0030507 spectrin binding(GO:0030507)
0.0 2.1 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 3.1 GO:0008013 beta-catenin binding(GO:0008013)
0.0 1.3 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.2 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 1.3 GO:0019905 syntaxin binding(GO:0019905)
0.0 5.8 GO:0035091 phosphatidylinositol binding(GO:0035091)
0.0 0.3 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.0 0.1 GO:0031419 cobalamin binding(GO:0031419)
0.0 2.9 GO:0002020 protease binding(GO:0002020)
0.0 2.1 GO:0005550 pheromone binding(GO:0005550)
0.0 9.1 GO:0004930 G-protein coupled receptor activity(GO:0004930)
0.0 0.8 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 2.5 GO:0044325 ion channel binding(GO:0044325)
0.0 0.5 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.8 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.5 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.4 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 3.6 GO:0008017 microtubule binding(GO:0008017)
0.0 1.2 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 0.4 GO:0008483 transaminase activity(GO:0008483)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 12.5 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.4 4.1 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.3 13.7 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.2 4.0 ST G ALPHA S PATHWAY G alpha s Pathway
0.2 3.3 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.2 9.5 PID GLYPICAN 1PATHWAY Glypican 1 network
0.2 13.7 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.2 8.8 PID RAS PATHWAY Regulation of Ras family activation
0.2 9.5 PID FAS PATHWAY FAS (CD95) signaling pathway
0.2 7.8 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.2 11.2 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.1 4.6 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.1 3.4 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.1 4.7 PID NETRIN PATHWAY Netrin-mediated signaling events
0.1 1.8 ST GA12 PATHWAY G alpha 12 Pathway
0.1 5.6 PID INSULIN PATHWAY Insulin Pathway
0.1 1.5 PID ERBB1 RECEPTOR PROXIMAL PATHWAY EGF receptor (ErbB1) signaling pathway
0.1 5.2 PID ENDOTHELIN PATHWAY Endothelins
0.1 18.9 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.1 4.4 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.1 2.9 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.1 2.0 PID CONE PATHWAY Visual signal transduction: Cones
0.1 15.6 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 6.0 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.0 0.4 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 1.4 PID RHOA PATHWAY RhoA signaling pathway
0.0 0.2 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 0.4 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 0.5 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 2.2 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 7.7 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 1.4 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 1.5 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.5 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.8 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.3 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 8.1 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.4 4.1 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.4 3.5 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.4 6.0 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.4 7.4 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.3 8.0 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.3 7.1 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.3 3.7 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.3 16.6 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.2 2.8 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.2 13.2 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.2 3.4 REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.2 6.7 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.2 3.0 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.2 6.7 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.2 2.9 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.2 5.6 REACTOME MUSCLE CONTRACTION Genes involved in Muscle contraction
0.2 6.6 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.2 6.4 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
0.1 3.1 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.1 3.2 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.1 5.0 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.1 4.9 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.1 1.8 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.1 2.3 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.1 2.9 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 3.8 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.1 0.5 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.1 17.3 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.1 1.8 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.1 1.5 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 1.8 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 3.3 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 1.2 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 7.2 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 4.3 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 2.1 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 3.2 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 2.8 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 1.1 REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)
0.0 1.9 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 1.6 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.5 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.5 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 0.7 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.4 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.4 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.4 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.4 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 1.3 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.5 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 1.3 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events