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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Tfcp2

Z-value: 1.57

Motif logo

Transcription factors associated with Tfcp2

Gene Symbol Gene ID Gene Info
ENSMUSG00000009733.10 Tfcp2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Tfcp2mm39_v1_chr15_-_100449839_1004498920.057.0e-01Click!

Activity profile of Tfcp2 motif

Sorted Z-values of Tfcp2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Tfcp2

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr10_+_43455919 20.13 ENSMUST00000214476.2
CD24a antigen
chr11_+_96820091 18.73 ENSMUST00000054311.6
ENSMUST00000107636.4
proline rich 15-like
chr10_+_43455157 14.97 ENSMUST00000058714.10
CD24a antigen
chr4_+_114945905 11.58 ENSMUST00000171877.8
ENSMUST00000177647.8
ENSMUST00000106548.9
ENSMUST00000030488.3
PDZK1 interacting protein 1
chr4_-_133329479 11.49 ENSMUST00000057311.4
stratifin
chr4_-_116024788 10.05 ENSMUST00000030465.10
ENSMUST00000143426.2
tetraspanin 1
chrX_+_55824797 9.18 ENSMUST00000114773.10
four and a half LIM domains 1
chr8_+_57964956 8.29 ENSMUST00000210871.2
high mobility group box 2
chr8_+_57964921 7.97 ENSMUST00000067925.8
high mobility group box 2
chr16_-_19079594 7.90 ENSMUST00000103752.3
ENSMUST00000197518.2
immunoglobulin lambda variable 2
chr11_-_95805710 7.50 ENSMUST00000038343.7
beta-1,4-N-acetyl-galactosaminyl transferase 2
chr19_-_34143437 7.33 ENSMUST00000025686.9
ankyrin repeat domain 22
chrX_-_111608339 7.31 ENSMUST00000039887.4
premature ovarian failure 1B
chr1_+_44590643 6.86 ENSMUST00000074525.10
GULP, engulfment adaptor PTB domain containing 1
chr19_-_38031774 6.80 ENSMUST00000226068.2
myoferlin
chr11_+_68936457 6.65 ENSMUST00000108666.8
ENSMUST00000021277.6
aurora kinase B
chr18_+_11766333 6.36 ENSMUST00000115861.9
retinoblastoma binding protein 8, endonuclease
chr1_+_90842785 6.29 ENSMUST00000027528.7
melanophilin
chr1_+_130659700 6.25 ENSMUST00000039323.8
expressed sequence AA986860
chr19_-_38032006 6.23 ENSMUST00000172095.3
ENSMUST00000041475.16
myoferlin
chr1_-_149836974 6.05 ENSMUST00000190507.2
ENSMUST00000070200.15
phospholipase A2, group IVA (cytosolic, calcium-dependent)
chr9_+_123902143 5.88 ENSMUST00000168841.3
ENSMUST00000055918.7
chemokine (C-C motif) receptor 2
chr14_+_75373766 5.76 ENSMUST00000145303.8
lymphocyte cytosolic protein 1
chr5_+_92957231 5.55 ENSMUST00000113054.9
shroom family member 3
chr1_+_131671751 5.43 ENSMUST00000049027.10
solute carrier family 26, member 9
chr12_-_114252202 5.30 ENSMUST00000195124.6
ENSMUST00000103481.3
immunoglobulin heavy variable 3-6
chr14_-_22039543 5.28 ENSMUST00000043409.9
zinc finger protein 503
chr9_+_15150341 5.27 ENSMUST00000034413.8
V-set and transmembrane domain containing 5
chr1_+_44590791 5.25 ENSMUST00000160854.8
GULP, engulfment adaptor PTB domain containing 1
chr18_+_44096300 5.23 ENSMUST00000069245.8
serine peptidase inhibitor, Kazal type 5
chr4_-_141325517 5.22 ENSMUST00000131317.8
ENSMUST00000006381.11
ENSMUST00000129602.8
filamin binding LIM protein 1
chr11_+_116423266 5.15 ENSMUST00000106386.8
ENSMUST00000145737.8
ENSMUST00000155102.8
ENSMUST00000063446.13
sphingosine kinase 1
chr19_-_5610628 5.10 ENSMUST00000025861.3
ovo like zinc finger 1
chr5_-_142892457 5.10 ENSMUST00000167721.8
ENSMUST00000163829.2
ENSMUST00000100497.11
actin, beta
chr3_+_92272486 5.07 ENSMUST00000050397.2
small proline-rich protein 2F
chr10_+_75407356 4.98 ENSMUST00000143226.8
ENSMUST00000124259.8
gamma-glutamyltransferase 1
chr17_+_28426752 4.93 ENSMUST00000002327.6
ENSMUST00000233560.2
ENSMUST00000233958.2
ENSMUST00000233170.2
differentially expressed in FDCP 6
chr5_+_53195423 4.79 ENSMUST00000170523.8
solute carrier family 34 (sodium phosphate), member 2
chr14_-_21898992 4.79 ENSMUST00000124549.9
catechol-O-methyltransferase domain containing 1
chr7_-_44983080 4.79 ENSMUST00000211743.2
ENSMUST00000042194.10
transient receptor potential cation channel, subfamily M, member 4
chr3_+_122522592 4.68 ENSMUST00000066728.10
phosphodiesterase 5A, cGMP-specific
chr13_-_100922910 4.67 ENSMUST00000174038.2
ENSMUST00000091295.14
ENSMUST00000072119.15
cyclin B1
chr11_-_8614497 4.65 ENSMUST00000020695.13
tensin 3
chr19_-_24178000 4.61 ENSMUST00000233658.3
tight junction protein 2
chr11_-_99328969 4.59 ENSMUST00000017743.3
keratin 20
chr8_+_70275079 4.42 ENSMUST00000164890.8
ENSMUST00000034325.6
ENSMUST00000238452.2
lysophosphatidic acid receptor 2
chr2_+_3705824 4.39 ENSMUST00000115054.9
family with sequence similarity 107, member B
chr7_+_130633776 4.32 ENSMUST00000084509.7
ENSMUST00000213064.3
ENSMUST00000208311.4
deleted in malignant brain tumors 1
chr18_-_64794338 4.25 ENSMUST00000025482.10
ATPase, class I, type 8B, member 1
chr2_-_148285450 4.22 ENSMUST00000099269.4
CD93 antigen
chr2_+_16361582 4.17 ENSMUST00000114703.10
plexin domain containing 2
chr11_+_28803188 4.15 ENSMUST00000020759.12
epidermal growth factor-containing fibulin-like extracellular matrix protein 1
chrX_-_36349055 4.09 ENSMUST00000115231.4
ribosomal protein L39
chr2_+_84966569 4.09 ENSMUST00000057019.9
apelin receptor
chr5_-_142891686 3.94 ENSMUST00000106216.3
actin, beta
chr14_-_54651442 3.85 ENSMUST00000227334.2
solute carrier family 7 (cationic amino acid transporter, y+ system), member 7
chr6_+_70675416 3.83 ENSMUST00000103403.3
immunoglobulin kappa variable 3-2
chr14_+_75373915 3.81 ENSMUST00000122840.8
lymphocyte cytosolic protein 1
chr2_-_167852538 3.76 ENSMUST00000099073.3
RIPOR family member 3
chr6_+_67838100 3.73 ENSMUST00000200586.2
ENSMUST00000103309.3
immunoglobulin kappa variable 17-127
chr1_-_133617824 3.72 ENSMUST00000189524.2
ENSMUST00000169295.8
lymphocyte transmembrane adaptor 1
chr12_-_114286421 3.72 ENSMUST00000103483.3
immunoglobulin heavy variable V3-8
chr6_-_52185674 3.66 ENSMUST00000062829.9
homeobox A6
chr15_-_97806142 3.58 ENSMUST00000023119.15
vitamin D (1,25-dihydroxyvitamin D3) receptor
chr8_-_105991219 3.51 ENSMUST00000034359.10
TNFRSF1A-associated via death domain
chr19_+_8906916 3.45 ENSMUST00000096241.6
echinoderm microtubule associated protein like 3
chr17_-_48758538 3.45 ENSMUST00000024794.12
translocator protein 2
chr10_-_18421628 3.31 ENSMUST00000213153.2
heme binding protein 2
chr9_-_99240571 3.27 ENSMUST00000042158.13
extended synaptotagmin-like protein 3
chr19_-_40576897 3.26 ENSMUST00000025979.13
aldehyde dehydrogenase 18 family, member A1
chr8_+_3715747 3.24 ENSMUST00000014118.4
mast cell expressed membrane protein 1
chr2_-_164024649 3.22 ENSMUST00000045127.12
WAP four-disulfide core domain 5
chr2_-_102016665 3.18 ENSMUST00000111222.2
low density lipoprotein receptor class A domain containing 3
chr3_-_90603013 3.15 ENSMUST00000069960.12
ENSMUST00000117167.2
S100 calcium binding protein A9 (calgranulin B)
chr11_-_8614667 3.12 ENSMUST00000239111.2
tensin 3
chr16_-_50252703 3.08 ENSMUST00000066037.13
ENSMUST00000089399.11
ENSMUST00000089404.10
ENSMUST00000138166.8
bobby sox HMG box containing
chr10_+_69048464 3.08 ENSMUST00000020101.12
Rho-related BTB domain containing 1
chr6_+_68916540 3.02 ENSMUST00000103339.2
immunoglobulin kappa chain variable 13-84
chr5_+_114924106 3.01 ENSMUST00000137519.2
ankyrin repeat domain 13a
chr11_+_48691175 2.96 ENSMUST00000020640.8
receptor for activated C kinase 1
chr14_+_79718604 2.94 ENSMUST00000040131.13
E74-like factor 1
chr10_+_13376745 2.91 ENSMUST00000060212.13
ENSMUST00000121465.3
fucosidase, alpha-L- 2, plasma
chr19_-_40576782 2.89 ENSMUST00000176939.8
aldehyde dehydrogenase 18 family, member A1
chr11_+_23206001 2.88 ENSMUST00000020538.13
ENSMUST00000109551.8
ENSMUST00000102870.8
ENSMUST00000102869.8
exportin 1
chr1_+_61677977 2.87 ENSMUST00000075374.10
par-3 family cell polarity regulator beta
chr8_+_124059414 2.80 ENSMUST00000010298.7
spire type actin nucleation factor 2
chr19_-_8690330 2.74 ENSMUST00000206598.2
solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2
chr12_-_113700190 2.69 ENSMUST00000103452.3
ENSMUST00000192264.2
immunoglobulin heavy variable 5-9-1
chr9_+_123901979 2.69 ENSMUST00000171719.8
chemokine (C-C motif) receptor 2
chr9_+_32283779 2.67 ENSMUST00000047334.10
potassium inwardly-rectifying channel, subfamily J, member 1
chr17_+_44445659 2.66 ENSMUST00000239215.2
chloride intracellular channel 5
chr4_-_132149704 2.62 ENSMUST00000152271.8
ENSMUST00000084170.12
phosphatase and actin regulator 4
chr5_-_142891565 2.58 ENSMUST00000171419.8
actin, beta
chr15_-_79976016 2.56 ENSMUST00000185306.3
ribosomal protein L3
chr6_+_22288220 2.54 ENSMUST00000128245.8
ENSMUST00000031681.10
ENSMUST00000148639.2
wingless-type MMTV integration site family, member 16
chr17_+_32671689 2.54 ENSMUST00000237491.2
cytochrome P450, family 4, subfamily f, polypeptide 39
chr2_-_165997179 2.51 ENSMUST00000088086.4
sulfatase 2
chr16_-_95928804 2.49 ENSMUST00000233292.2
ENSMUST00000050884.16
high mobility group nucleosomal binding domain 1
chr19_-_40576817 2.39 ENSMUST00000175932.2
ENSMUST00000176955.8
ENSMUST00000149476.3
aldehyde dehydrogenase 18 family, member A1
chr16_-_3725515 2.38 ENSMUST00000177221.2
ENSMUST00000177323.8
RIKEN cDNA 1700037C18 gene
chr6_-_43643093 2.36 ENSMUST00000114644.8
ENSMUST00000067888.14
thiamine pyrophosphokinase
chr2_-_102016717 2.33 ENSMUST00000058790.12
low density lipoprotein receptor class A domain containing 3
chr1_+_34890912 2.33 ENSMUST00000152654.3
pleckstrin homology domain containing, family B (evectins) member 2
chr2_-_165997551 2.32 ENSMUST00000109249.9
ENSMUST00000146497.9
sulfatase 2
chr9_+_50768224 2.32 ENSMUST00000174628.8
ENSMUST00000034560.14
ENSMUST00000114437.9
ENSMUST00000175645.8
ENSMUST00000176349.8
ENSMUST00000176798.8
ENSMUST00000175640.8
protein phosphatase 2, regulatory subunit A, beta
chr2_-_164024512 2.30 ENSMUST00000131974.2
WAP four-disulfide core domain 5
chr5_+_33815466 2.30 ENSMUST00000074849.13
ENSMUST00000079534.11
ENSMUST00000201633.2
transforming, acidic coiled-coil containing protein 3
chr17_+_28426831 2.29 ENSMUST00000233264.2
differentially expressed in FDCP 6
chr12_-_54703281 2.28 ENSMUST00000056228.8
serine palmitoyltransferase, small subunit A
chr6_-_47790272 2.26 ENSMUST00000077290.9
protein disulfide isomerase associated 4
chr17_-_24746804 2.25 ENSMUST00000176353.8
ENSMUST00000176237.8
TNF receptor-associated factor 7
chr5_-_30278552 2.23 ENSMUST00000198095.2
ENSMUST00000196872.2
ENSMUST00000026846.11
thymidylate synthase
chr9_-_67739607 2.21 ENSMUST00000054500.7
C2 calcium-dependent domain containing 4A
chr7_+_141027763 2.19 ENSMUST00000106003.2
ribosomal protein, large P2
chr2_+_127696548 2.15 ENSMUST00000028859.8
acyl-Coenzyme A oxidase-like
chr4_-_154110073 2.14 ENSMUST00000182191.8
ENSMUST00000146543.9
ENSMUST00000146426.2
small integral membrane protein 1
chr10_+_69048506 2.13 ENSMUST00000167384.8
Rho-related BTB domain containing 1
chr18_+_65564009 2.12 ENSMUST00000224056.3
ENSMUST00000049248.7
MALT1 paracaspase
chr2_-_84605732 2.12 ENSMUST00000023994.10
serine (or cysteine) peptidase inhibitor, clade G, member 1
chr17_-_24746911 2.11 ENSMUST00000176652.8
TNF receptor-associated factor 7
chr19_-_45738002 2.09 ENSMUST00000070215.8
nucleoplasmin 3
chr10_+_21870565 2.06 ENSMUST00000020145.12
serum/glucocorticoid regulated kinase 1
chr4_-_63663344 2.05 ENSMUST00000239480.2
ENSMUST00000062246.8
tumor necrosis factor (ligand) superfamily, member 15
chr7_+_43441315 2.05 ENSMUST00000005891.7
kallikrein related-peptidase 9
chr14_+_59716265 2.05 ENSMUST00000224893.2
calcium binding protein 39-like
chr16_-_16345197 2.03 ENSMUST00000069284.14
FYVE, RhoGEF and PH domain containing 4
chr11_+_110888313 2.02 ENSMUST00000106635.2
potassium inwardly-rectifying channel, subfamily J, member 16
chrX_-_74174524 1.99 ENSMUST00000114091.8
membrane protein, palmitoylated
chr5_+_135015046 1.99 ENSMUST00000094245.4
claudin 3
chr6_-_34294377 1.99 ENSMUST00000154655.2
ENSMUST00000102980.11
aldo-keto reductase family 1, member B3 (aldose reductase)
chr2_-_84605764 1.97 ENSMUST00000111641.2
serine (or cysteine) peptidase inhibitor, clade G, member 1
chr17_-_71153283 1.94 ENSMUST00000156484.2
TGFB-induced factor homeobox 1
chr10_+_79855454 1.93 ENSMUST00000043311.7
Rho GTPase activating protein 45
chr1_-_52230062 1.93 ENSMUST00000156887.8
ENSMUST00000129107.2
glutaminase
chr9_+_35334878 1.91 ENSMUST00000154652.8
cell adhesion molecule-related/down-regulated by oncogenes
chr15_+_89206923 1.88 ENSMUST00000066991.7
adrenomedullin 2
chr3_-_58433313 1.87 ENSMUST00000029385.9
stress-associated endoplasmic reticulum protein 1
chr17_-_34218301 1.87 ENSMUST00000235463.2
histocompatibility 2, K1, K region
chr3_+_79793237 1.86 ENSMUST00000029567.9
golgi associated kinase 1B
chr11_+_69805005 1.85 ENSMUST00000057884.6
G protein pathway suppressor 2
chr17_+_35278011 1.79 ENSMUST00000007255.13
ENSMUST00000174493.8
dimethylarginine dimethylaminohydrolase 2
chr12_+_24758968 1.79 ENSMUST00000154588.2
ribonucleotide reductase M2
chrX_+_138464065 1.78 ENSMUST00000113027.8
ring finger protein 128
chr4_-_132149780 1.76 ENSMUST00000102568.10
phosphatase and actin regulator 4
chr14_-_34096574 1.76 ENSMUST00000023826.5
synuclein, gamma
chr2_+_70339175 1.75 ENSMUST00000134607.8
glutamate rich 2
chr18_+_61688329 1.75 ENSMUST00000165123.8
casein kinase 1, alpha 1
chr19_+_8907206 1.73 ENSMUST00000224272.2
echinoderm microtubule associated protein like 3
chr6_-_142517340 1.73 ENSMUST00000203945.3
potassium inwardly-rectifying channel, subfamily J, member 8
chr3_-_143908111 1.73 ENSMUST00000121796.8
LIM domain only 4
chr8_+_105991280 1.71 ENSMUST00000036221.12
F-box and leucine-rich repeat protein 8
chr1_-_173426640 1.68 ENSMUST00000150649.9
ENSMUST00000180215.2
ENSMUST00000097462.9
interferon activated gene 213
chr1_-_85087567 1.68 ENSMUST00000161675.3
ENSMUST00000160792.8
RIKEN cDNA A530032D15Rik gene
chr7_+_141047416 1.68 ENSMUST00000209988.2
CD151 antigen
chr11_-_45846291 1.67 ENSMUST00000011398.13
tRNA-histidine guanylyltransferase 1-like (S. cerevisiae)
chr2_+_70339157 1.66 ENSMUST00000100041.9
glutamate rich 2
chrX_+_7708295 1.60 ENSMUST00000115667.10
ENSMUST00000115668.10
ENSMUST00000115665.2
OTU domain containing 5
chr3_-_143908060 1.59 ENSMUST00000121112.6
LIM domain only 4
chr15_+_76929275 1.58 ENSMUST00000127957.8
ENSMUST00000129468.8
ENSMUST00000149569.9
ENSMUST00000152949.2
apolipoprotein L 6
chr3_+_63203516 1.54 ENSMUST00000029400.7
membrane metallo endopeptidase
chr1_-_194813843 1.53 ENSMUST00000075451.12
ENSMUST00000191775.2
complement component (3b/4b) receptor 1-like
chr5_-_34794185 1.53 ENSMUST00000149657.5
major facilitator superfamily domain containing 10
chr5_+_33815910 1.53 ENSMUST00000114426.10
transforming, acidic coiled-coil containing protein 3
chr1_+_16758629 1.51 ENSMUST00000026881.11
lymphocyte antigen 96
chr4_-_154110324 1.51 ENSMUST00000130175.8
ENSMUST00000182151.8
small integral membrane protein 1
chr12_-_30423356 1.50 ENSMUST00000021004.14
syntrophin, gamma 2
chr11_-_45845992 1.48 ENSMUST00000109254.2
tRNA-histidine guanylyltransferase 1-like (S. cerevisiae)
chr5_+_43819688 1.47 ENSMUST00000048150.15
coiled-coil and C2 domain containing 2A
chr12_+_105570350 1.47 ENSMUST00000041229.5
bradykinin receptor, beta 1
chr14_+_30201569 1.45 ENSMUST00000022535.9
ENSMUST00000223658.2
decapping mRNA 1A
chr5_+_107112186 1.45 ENSMUST00000117196.9
ENSMUST00000031221.12
ENSMUST00000076467.13
cell division cycle 7 (S. cerevisiae)
chr6_+_122967309 1.44 ENSMUST00000079379.3
C-type lectin domain family 4, member a4
chr14_+_26414422 1.43 ENSMUST00000022433.12
dynein, axonemal, heavy chain 12
chr7_+_101619019 1.43 ENSMUST00000084852.13
nuclear mitotic apparatus protein 1
chrX_+_7708034 1.40 ENSMUST00000033494.16
ENSMUST00000115666.8
OTU domain containing 5
chr18_+_61688378 1.36 ENSMUST00000165721.8
ENSMUST00000115246.9
ENSMUST00000166990.8
ENSMUST00000163205.8
ENSMUST00000170862.8
casein kinase 1, alpha 1
chr19_-_46917661 1.35 ENSMUST00000236727.2
5'-nucleotidase, cytosolic II
chr11_-_35871300 1.32 ENSMUST00000018993.7
WW, C2 and coiled-coil domain containing 1
chr9_-_109063792 1.32 ENSMUST00000197329.2
ENSMUST00000079548.12
F-box and WD-40 domain protein 20
chr4_-_154110383 1.31 ENSMUST00000132541.8
ENSMUST00000143047.8
small integral membrane protein 1
chr4_+_107111106 1.30 ENSMUST00000046558.8
heat shock protein family B (small), member 11
chr19_-_8906686 1.30 ENSMUST00000096242.5
rod outer segment membrane protein 1
chr4_+_107111083 1.30 ENSMUST00000106749.8
heat shock protein family B (small), member 11
chr14_+_120543857 1.25 ENSMUST00000227594.2
muscleblind like splicing factor 2
chr7_+_113113292 1.24 ENSMUST00000122890.2
fatty acyl CoA reductase 1
chr14_+_54312354 1.22 ENSMUST00000103679.3
T cell receptor delta variable 4
chr2_+_89808124 1.19 ENSMUST00000061830.2
olfactory receptor 1260
chr5_-_100648487 1.15 ENSMUST00000239512.1
lin-54 homolog (C. elegans)
chr17_+_34812361 1.12 ENSMUST00000174532.2
pre B cell leukemia homeobox 2
chr10_+_66932235 1.10 ENSMUST00000174317.8
jumonji domain containing 1C
chrX_+_163763588 1.10 ENSMUST00000167446.8
ENSMUST00000057150.8
Fanconi anemia, complementation group B
chr15_-_77480311 1.09 ENSMUST00000089465.6
apolipoprotein L 10B
chr8_-_111573401 1.08 ENSMUST00000042012.7
splicing factor 3b, subunit 3
chr1_+_173501215 1.06 ENSMUST00000085876.12
interferon activated gene 208
chr16_-_32630847 1.04 ENSMUST00000179384.3
somatomedin B domain containing 1
chr7_-_35096133 1.03 ENSMUST00000154597.2
ENSMUST00000032704.12
Fanconi anemia core complex associated protein 24
chr11_-_102207516 1.03 ENSMUST00000107115.8
ENSMUST00000128016.2
upstream binding transcription factor, RNA polymerase I
chr11_-_102207486 1.01 ENSMUST00000146896.9
ENSMUST00000079589.11
upstream binding transcription factor, RNA polymerase I
chr11_+_75422516 1.01 ENSMUST00000149727.8
ENSMUST00000108433.8
ENSMUST00000042561.14
ENSMUST00000143035.8
solute carrier family 43, member 2
chrX_+_72683020 1.00 ENSMUST00000019701.9
dual specificity phosphatase 9

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
11.7 35.1 GO:0034117 erythrocyte aggregation(GO:0034117) regulation of erythrocyte aggregation(GO:0034118)
3.9 11.6 GO:0098974 postsynaptic actin cytoskeleton organization(GO:0098974)
3.8 11.5 GO:0010481 epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
2.9 8.6 GO:0002436 immune complex clearance by monocytes and macrophages(GO:0002436) regulation of immune complex clearance by monocytes and macrophages(GO:0090264) positive regulation of immune complex clearance by monocytes and macrophages(GO:0090265) negative regulation of eosinophil activation(GO:1902567) positive regulation of CD8-positive, alpha-beta T cell extravasation(GO:2000451)
2.8 8.5 GO:0006592 ornithine biosynthetic process(GO:0006592)
2.2 6.6 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
1.7 5.1 GO:1901994 negative regulation of meiotic cell cycle phase transition(GO:1901994)
1.6 16.3 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
1.6 4.8 GO:1903116 positive regulation of actin filament-based movement(GO:1903116)
1.4 4.1 GO:0001869 regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869)
1.4 4.1 GO:0002030 inhibitory G-protein coupled receptor phosphorylation(GO:0002030)
1.3 7.5 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
1.2 4.7 GO:0031660 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662)
1.1 4.4 GO:0061386 closure of optic fissure(GO:0061386)
1.1 5.3 GO:0070315 G1 to G0 transition involved in cell differentiation(GO:0070315)
1.1 3.2 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
1.0 4.2 GO:0010980 regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980)
0.9 5.2 GO:0002786 regulation of antimicrobial peptide production(GO:0002784) regulation of antibacterial peptide production(GO:0002786)
0.9 6.1 GO:2001280 positive regulation of prostaglandin biosynthetic process(GO:0031394) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.9 5.2 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.8 2.5 GO:0000720 pyrimidine dimer repair by nucleotide-excision repair(GO:0000720)
0.8 4.8 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.8 4.8 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.8 4.7 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.8 2.3 GO:1903334 positive regulation of protein folding(GO:1903334)
0.7 3.0 GO:1905077 negative regulation of interleukin-17 secretion(GO:1905077)
0.7 3.0 GO:0090004 positive regulation of Golgi to plasma membrane protein transport(GO:0042998) positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
0.7 13.0 GO:0001778 plasma membrane repair(GO:0001778)
0.7 6.4 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.7 2.8 GO:0070649 formin-nucleated actin cable assembly(GO:0070649)
0.7 2.0 GO:0090420 hexitol metabolic process(GO:0006059) naphthalene metabolic process(GO:0018931) naphthalene-containing compound metabolic process(GO:0090420)
0.7 4.6 GO:2001205 negative regulation of osteoclast development(GO:2001205)
0.6 5.0 GO:0031179 peptide modification(GO:0031179) leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.6 2.4 GO:0006772 thiamine metabolic process(GO:0006772) thiamine-containing compound metabolic process(GO:0042723)
0.5 2.7 GO:0060356 leucine import(GO:0060356)
0.5 4.3 GO:0021650 vestibulocochlear nerve formation(GO:0021650)
0.5 6.3 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.5 2.5 GO:0090403 oxidative stress-induced premature senescence(GO:0090403)
0.5 3.8 GO:0000821 regulation of arginine metabolic process(GO:0000821)
0.5 3.3 GO:0010940 positive regulation of necrotic cell death(GO:0010940)
0.4 2.2 GO:0006231 dTMP biosynthetic process(GO:0006231) dTMP metabolic process(GO:0046073)
0.4 2.1 GO:0001923 B-1 B cell differentiation(GO:0001923)
0.4 9.6 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.4 1.5 GO:0015904 tetracycline transport(GO:0015904)
0.4 1.9 GO:0002484 antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway(GO:0002484) antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent(GO:0002485)
0.4 1.1 GO:1905168 positive regulation of double-strand break repair via homologous recombination(GO:1905168)
0.4 1.4 GO:1902365 regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846)
0.3 4.4 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.3 2.7 GO:0070294 renal sodium ion absorption(GO:0070294)
0.3 2.9 GO:0006004 fucose metabolic process(GO:0006004)
0.3 1.9 GO:0006543 glutamine catabolic process(GO:0006543)
0.3 3.2 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.3 2.1 GO:0045916 negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.3 1.5 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.3 4.1 GO:0002227 innate immune response in mucosa(GO:0002227)
0.3 2.0 GO:0030035 microspike assembly(GO:0030035)
0.3 5.2 GO:0033623 regulation of integrin activation(GO:0033623)
0.3 1.9 GO:0032497 detection of lipopolysaccharide(GO:0032497)
0.3 4.2 GO:1903975 regulation of glial cell migration(GO:1903975)
0.2 5.4 GO:0008272 sulfate transport(GO:0008272)
0.2 1.5 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.2 0.7 GO:1904211 membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211)
0.2 3.5 GO:0051798 positive regulation of hair follicle development(GO:0051798)
0.2 1.1 GO:1902728 positive regulation of skeletal muscle satellite cell proliferation(GO:1902724) positive regulation of growth factor dependent skeletal muscle satellite cell proliferation(GO:1902728)
0.2 1.5 GO:0071492 cellular response to UV-A(GO:0071492)
0.2 0.6 GO:0048003 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.2 1.2 GO:0010025 wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.2 2.0 GO:0006362 transcription elongation from RNA polymerase I promoter(GO:0006362)
0.2 2.0 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.2 3.1 GO:1904424 regulation of GTP binding(GO:1904424)
0.2 1.9 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816)
0.2 3.8 GO:0030953 astral microtubule organization(GO:0030953)
0.2 4.3 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.2 9.2 GO:0010972 negative regulation of G2/M transition of mitotic cell cycle(GO:0010972)
0.2 0.7 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.2 0.9 GO:0048687 positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691)
0.2 0.9 GO:0046882 negative regulation of follicle-stimulating hormone secretion(GO:0046882)
0.2 0.5 GO:0097401 synaptic vesicle lumen acidification(GO:0097401)
0.2 3.3 GO:0021527 spinal cord association neuron differentiation(GO:0021527)
0.2 1.7 GO:0098915 membrane repolarization during ventricular cardiac muscle cell action potential(GO:0098915) potassium ion import across plasma membrane(GO:1990573)
0.2 1.8 GO:0006527 arginine catabolic process(GO:0006527)
0.2 1.5 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.2 3.5 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.1 4.6 GO:0045109 intermediate filament organization(GO:0045109)
0.1 0.7 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.1 5.1 GO:0031424 keratinization(GO:0031424)
0.1 1.3 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.1 2.1 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.1 23.0 GO:0006911 phagocytosis, engulfment(GO:0006911)
0.1 0.8 GO:0051771 negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.1 2.7 GO:0002024 diet induced thermogenesis(GO:0002024)
0.1 2.6 GO:0070986 left/right axis specification(GO:0070986)
0.1 1.0 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.1 0.9 GO:0010757 negative regulation of plasminogen activation(GO:0010757)
0.1 7.3 GO:0070830 bicellular tight junction assembly(GO:0070830)
0.1 0.8 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.1 1.9 GO:0060124 positive regulation of growth hormone secretion(GO:0060124)
0.1 1.9 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.1 1.8 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.1 1.1 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.1 0.5 GO:0006166 purine ribonucleoside salvage(GO:0006166)
0.1 2.1 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.1 4.4 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.1 0.6 GO:0019348 dolichol metabolic process(GO:0019348)
0.1 2.9 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.1 9.0 GO:0048286 lung alveolus development(GO:0048286)
0.1 2.2 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.1 0.3 GO:0044376 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.1 1.4 GO:0036159 inner dynein arm assembly(GO:0036159)
0.1 0.7 GO:0010756 regulation of plasminogen activation(GO:0010755) positive regulation of plasminogen activation(GO:0010756)
0.1 1.0 GO:0046085 adenosine metabolic process(GO:0046085)
0.1 5.5 GO:0070613 regulation of protein processing(GO:0070613)
0.1 1.4 GO:0040034 regulation of development, heterochronic(GO:0040034)
0.1 2.1 GO:0009303 rRNA transcription(GO:0009303)
0.1 0.7 GO:1901550 regulation of endothelial cell development(GO:1901550) regulation of establishment of endothelial barrier(GO:1903140)
0.1 0.2 GO:0046087 cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
0.1 0.4 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.1 0.4 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.1 2.6 GO:0071353 cellular response to interleukin-4(GO:0071353)
0.1 0.5 GO:1901029 negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
0.1 1.9 GO:0060561 apoptotic process involved in morphogenesis(GO:0060561)
0.1 0.8 GO:0070601 centromeric sister chromatid cohesion(GO:0070601)
0.1 2.0 GO:0090022 regulation of neutrophil chemotaxis(GO:0090022)
0.1 2.0 GO:0010107 potassium ion import(GO:0010107)
0.1 1.0 GO:0048642 negative regulation of skeletal muscle tissue development(GO:0048642)
0.1 1.3 GO:0061298 retina vasculature development in camera-type eye(GO:0061298)
0.1 4.6 GO:0002066 columnar/cuboidal epithelial cell development(GO:0002066)
0.1 3.4 GO:0045776 negative regulation of blood pressure(GO:0045776)
0.0 0.7 GO:0070072 vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 1.8 GO:0042036 negative regulation of cytokine biosynthetic process(GO:0042036)
0.0 0.5 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.0 9.2 GO:0050821 protein stabilization(GO:0050821)
0.0 0.2 GO:0090222 centrosome-templated microtubule nucleation(GO:0090222)
0.0 0.2 GO:0071110 protein biotinylation(GO:0009305) response to biotin(GO:0070781) histone biotinylation(GO:0071110)
0.0 1.8 GO:0046329 negative regulation of JNK cascade(GO:0046329)
0.0 2.3 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.0 2.2 GO:0006414 translational elongation(GO:0006414)
0.0 1.1 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.0 7.6 GO:0002377 immunoglobulin production(GO:0002377)
0.0 0.1 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.0 2.3 GO:0006400 tRNA modification(GO:0006400)
0.0 0.2 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.0 3.7 GO:0048704 embryonic skeletal system morphogenesis(GO:0048704)
0.0 4.4 GO:0007605 sensory perception of sound(GO:0007605)
0.0 0.1 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.1 GO:0090306 spindle assembly involved in meiosis(GO:0090306)
0.0 0.4 GO:0043486 histone exchange(GO:0043486)
0.0 0.5 GO:0030502 negative regulation of bone mineralization(GO:0030502)
0.0 0.1 GO:0007341 penetration of zona pellucida(GO:0007341)
0.0 0.2 GO:0006098 pentose-phosphate shunt(GO:0006098)
0.0 0.4 GO:0010800 positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.0 0.7 GO:0019369 arachidonic acid metabolic process(GO:0019369)
0.0 1.7 GO:0060348 bone development(GO:0060348)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 35.1 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
1.2 4.7 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
1.1 6.6 GO:0032133 chromosome passenger complex(GO:0032133)
1.0 5.2 GO:0097209 epidermal lamellar body(GO:0097209)
1.0 3.0 GO:1990630 IRE1-RACK1-PP2A complex(GO:1990630)
0.4 3.6 GO:0001651 dense fibrillar component(GO:0001651)
0.4 2.0 GO:0097454 Schwann cell microvillus(GO:0097454)
0.4 21.2 GO:0002102 podosome(GO:0002102)
0.4 6.3 GO:0016461 unconventional myosin complex(GO:0016461)
0.3 4.3 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.3 1.8 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.3 1.4 GO:0061673 mitotic spindle astral microtubule(GO:0061673)
0.3 1.9 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.3 2.3 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.2 2.9 GO:0005642 annulate lamellae(GO:0005642)
0.2 7.3 GO:0030057 desmosome(GO:0030057)
0.2 3.1 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.2 1.7 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.2 4.8 GO:0031528 microvillus membrane(GO:0031528)
0.2 0.9 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.2 6.1 GO:0042588 zymogen granule(GO:0042588)
0.2 0.6 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.2 3.3 GO:0044232 organelle membrane contact site(GO:0044232)
0.2 2.3 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 4.8 GO:0034706 sodium channel complex(GO:0034706)
0.1 1.0 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.1 1.9 GO:0042612 MHC class I protein complex(GO:0042612)
0.1 6.9 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.1 2.1 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.1 1.4 GO:0036156 inner dynein arm(GO:0036156)
0.1 8.8 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.1 4.6 GO:0005921 gap junction(GO:0005921)
0.1 5.1 GO:0001533 cornified envelope(GO:0001533)
0.1 0.5 GO:0071817 MMXD complex(GO:0071817)
0.1 1.3 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.1 10.9 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.1 0.7 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.1 6.9 GO:0032420 stereocilium(GO:0032420)
0.1 1.5 GO:0036038 MKS complex(GO:0036038)
0.1 13.0 GO:0005901 caveola(GO:0005901)
0.1 2.0 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 0.8 GO:0031415 NatA complex(GO:0031415)
0.1 0.7 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.1 7.5 GO:0017053 transcriptional repressor complex(GO:0017053)
0.1 1.8 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 2.8 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 9.1 GO:0001650 fibrillar center(GO:0001650)
0.0 14.6 GO:0000793 condensed chromosome(GO:0000793)
0.0 6.3 GO:0005604 basement membrane(GO:0005604)
0.0 8.4 GO:0043296 apical junction complex(GO:0043296)
0.0 0.6 GO:0097539 ciliary transition fiber(GO:0097539)
0.0 4.6 GO:0005882 intermediate filament(GO:0005882)
0.0 6.4 GO:0030027 lamellipodium(GO:0030027)
0.0 0.5 GO:0042581 specific granule(GO:0042581)
0.0 0.1 GO:1990716 axonemal central apparatus(GO:1990716)
0.0 0.8 GO:0005779 integral component of peroxisomal membrane(GO:0005779)
0.0 14.1 GO:0005925 focal adhesion(GO:0005925)
0.0 5.8 GO:0098857 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 4.0 GO:0030139 endocytic vesicle(GO:0030139)
0.0 8.9 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 1.5 GO:0045171 intercellular bridge(GO:0045171)
0.0 1.4 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 1.5 GO:0031526 brush border membrane(GO:0031526)
0.0 2.0 GO:0030863 cortical cytoskeleton(GO:0030863)
0.0 1.3 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.9 GO:0099738 cell cortex region(GO:0099738)
0.0 2.5 GO:0031252 cell leading edge(GO:0031252)
0.0 7.5 GO:0031012 extracellular matrix(GO:0031012)
0.0 0.4 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 3.1 GO:0005911 cell-cell junction(GO:0005911)
0.0 3.2 GO:0016324 apical plasma membrane(GO:0016324)
0.0 1.7 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.0 0.2 GO:0005652 nuclear lamina(GO:0005652)
0.0 0.4 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 0.1 GO:0000137 Golgi cis cisterna(GO:0000137)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
3.9 11.6 GO:0098973 structural constituent of synapse(GO:0098918) structural constituent of postsynaptic actin cytoskeleton(GO:0098973)
2.9 8.6 GO:0035717 chemokine (C-C motif) ligand 7 binding(GO:0035717)
2.8 8.5 GO:0004349 glutamate 5-kinase activity(GO:0004349) glutamate-5-semialdehyde dehydrogenase activity(GO:0004350) delta1-pyrroline-5-carboxylate synthetase activity(GO:0017084) amino acid kinase activity(GO:0019202)
1.9 19.4 GO:0050786 RAGE receptor binding(GO:0050786)
1.5 35.1 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
1.4 4.3 GO:0035375 zymogen binding(GO:0035375)
1.2 3.6 GO:1902121 lithocholic acid binding(GO:1902121)
1.1 3.2 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
1.0 4.2 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
1.0 2.9 GO:0004560 alpha-L-fucosidase activity(GO:0004560) fucosidase activity(GO:0015928)
1.0 4.8 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.8 4.7 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.7 4.8 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.7 6.1 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.6 5.2 GO:0008481 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.5 4.4 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.5 4.4 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.5 4.2 GO:0001849 complement component C1q binding(GO:0001849)
0.5 1.5 GO:0004947 bradykinin receptor activity(GO:0004947)
0.5 2.4 GO:0016778 diphosphotransferase activity(GO:0016778)
0.5 2.3 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.5 6.4 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.4 4.3 GO:1901612 cardiolipin binding(GO:1901612)
0.4 5.0 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.4 1.5 GO:0008493 tetracycline transporter activity(GO:0008493)
0.4 3.0 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.4 3.0 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.3 2.0 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.3 7.7 GO:0051010 microtubule plus-end binding(GO:0051010)
0.3 1.9 GO:0004359 glutaminase activity(GO:0004359)
0.3 1.9 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.3 1.8 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.3 6.6 GO:0035174 histone serine kinase activity(GO:0035174)
0.3 5.4 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.3 2.1 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.2 2.0 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.2 1.2 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.2 0.9 GO:0051431 corticotropin-releasing hormone receptor 2 binding(GO:0051431)
0.2 2.8 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.2 4.1 GO:0001848 complement binding(GO:0001848)
0.2 7.5 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.2 5.2 GO:0031005 filamin binding(GO:0031005)
0.2 2.2 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.2 2.2 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.2 2.6 GO:0008097 5S rRNA binding(GO:0008097)
0.2 3.5 GO:0070513 death domain binding(GO:0070513)
0.2 4.7 GO:0030553 cGMP binding(GO:0030553)
0.2 0.5 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.2 1.8 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.2 4.8 GO:0008171 O-methyltransferase activity(GO:0008171)
0.2 0.6 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.1 0.5 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.1 1.0 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.1 0.8 GO:0004661 protein geranylgeranyltransferase activity(GO:0004661)
0.1 2.3 GO:0015037 peptide disulfide oxidoreductase activity(GO:0015037)
0.1 2.6 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.1 1.9 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.1 1.5 GO:0097109 neuroligin family protein binding(GO:0097109)
0.1 1.1 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.1 0.7 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.1 0.8 GO:0004568 chitinase activity(GO:0004568)
0.1 0.9 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.1 18.8 GO:0003823 antigen binding(GO:0003823)
0.1 3.7 GO:0042169 SH2 domain binding(GO:0042169)
0.1 0.2 GO:0047936 glucose 1-dehydrogenase [NAD(P)] activity(GO:0047936)
0.1 4.2 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.1 22.4 GO:0051015 actin filament binding(GO:0051015)
0.1 2.1 GO:0005123 death receptor binding(GO:0005123)
0.1 3.7 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.1 2.0 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.1 12.5 GO:0051219 phosphoprotein binding(GO:0051219)
0.1 0.4 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.1 0.7 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.1 1.3 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.1 2.2 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.1 0.4 GO:0032453 histone demethylase activity (H3-K4 specific)(GO:0032453)
0.1 0.2 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.1 1.1 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.5 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.0 1.4 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 3.2 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 3.4 GO:0015485 cholesterol binding(GO:0015485)
0.0 2.2 GO:0005109 frizzled binding(GO:0005109)
0.0 0.2 GO:0004080 biotin-[acetyl-CoA-carboxylase] ligase activity(GO:0004077) biotin-[methylcrotonoyl-CoA-carboxylase] ligase activity(GO:0004078) biotin-[methylmalonyl-CoA-carboxytransferase] ligase activity(GO:0004079) biotin-[propionyl-CoA-carboxylase (ATP-hydrolyzing)] ligase activity(GO:0004080) biotin-protein ligase activity(GO:0018271)
0.0 10.0 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 1.8 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.2 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.0 0.8 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 5.0 GO:0030674 protein binding, bridging(GO:0030674)
0.0 2.5 GO:0019209 kinase activator activity(GO:0019209)
0.0 7.1 GO:0044325 ion channel binding(GO:0044325)
0.0 6.3 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 4.4 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.1 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.0 11.7 GO:0005198 structural molecule activity(GO:0005198)
0.0 1.5 GO:0019894 kinesin binding(GO:0019894)
0.0 1.0 GO:0004180 carboxypeptidase activity(GO:0004180)
0.0 0.6 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 1.5 GO:0008238 exopeptidase activity(GO:0008238)
0.0 1.0 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.1 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.0 6.5 GO:0005543 phospholipid binding(GO:0005543)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 11.5 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.2 12.1 PID ARF6 PATHWAY Arf6 signaling events
0.2 11.3 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.2 5.8 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.2 6.4 PID ATM PATHWAY ATM pathway
0.1 2.9 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.1 5.1 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.1 16.9 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.1 6.1 PID ENDOTHELIN PATHWAY Endothelins
0.1 3.5 PID TRAIL PATHWAY TRAIL signaling pathway
0.1 13.0 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.1 4.5 PID IL6 7 PATHWAY IL6-mediated signaling events
0.1 4.4 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.1 2.9 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.1 7.2 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.1 1.9 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.1 2.8 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.1 4.5 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1 4.0 PID E2F PATHWAY E2F transcription factor network
0.1 2.1 PID FOXO PATHWAY FoxO family signaling
0.1 1.9 PID AURORA A PATHWAY Aurora A signaling
0.1 4.6 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 1.0 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 3.4 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 2.0 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 9.5 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.1 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 4.2 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.6 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.7 PID BMP PATHWAY BMP receptor signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 16.3 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
1.0 8.6 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.4 4.7 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.3 6.1 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.3 11.4 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.2 5.1 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.2 4.6 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.2 3.5 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.2 2.0 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.2 4.1 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.2 5.2 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.2 6.4 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.1 6.6 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.1 1.9 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.1 4.7 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.1 2.4 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.1 4.5 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.1 2.9 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.1 5.0 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.1 1.4 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.1 6.4 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.1 9.5 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.1 1.3 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.1 4.3 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.1 8.8 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.1 1.1 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.1 1.5 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.1 9.3 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.1 1.1 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.1 1.3 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.1 1.1 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.1 2.9 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.1 1.3 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.1 1.9 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 2.0 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 10.6 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.0 4.1 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.9 REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS Genes involved in Activation of ATR in response to replication stress
0.0 3.6 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 1.9 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.6 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 7.2 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 2.4 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 1.7 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.0 0.7 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.5 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.9 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.8 REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS Genes involved in Interactions of Vpr with host cellular proteins
0.0 1.1 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 0.6 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.6 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.9 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells