ISMARA results: Tlx2

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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Tlx2

Z-value: 1.67

Motif logo

Transcription factors associated with Tlx2

Gene Symbol	Gene ID	Gene Info
Tlx2 Ensembl NCBI MGI UniProt	ENSMUSG00000068327.6	Tlx2

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
Tlx2	mm39_v1_chr6_-_83047206_83047361	0.02	8.6e-01	Click!

Activity profile of Tlx2 motif

Sorted Z-values of Tlx2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Tlx2

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View png image

Top targets:

Promoter	Score	Transcript	Gene	Gene Info
chr19_-_11243530 Show fit	15.02	ENSMUST00000169159.3	Ms4a1 Ensembl NCBI MGI UniProt Show fit	membrane-spanning 4-domains, subfamily A, member 1
chr3_+_90576285 Show fit	10.37	ENSMUST00000069927.10	S100a8 Ensembl NCBI MGI UniProt Show fit	S100 calcium binding protein A8 (calgranulin A)
chr17_+_35413415 Show fit	10.33	ENSMUST00000025262.6 ENSMUST00000173600.2	Ltb Ensembl NCBI MGI UniProt Show fit	lymphotoxin B
chr3_-_90603013 Show fit	9.97	ENSMUST00000069960.12 ENSMUST00000117167.2	S100a9 Ensembl NCBI MGI UniProt Show fit	S100 calcium binding protein A9 (calgranulin B)
chr6_+_41520150 Show fit	9.60	ENSMUST00000103295.2	Trbj2-3 Ensembl NCBI MGI UniProt Show fit	T cell receptor beta joining 2-3
chr5_-_105198913 Show fit	9.57	ENSMUST00000112718.5	Gbp8 Ensembl NCBI MGI UniProt Show fit	guanylate-binding protein 8
chr11_-_52173391 Show fit	8.48	ENSMUST00000086844.10	Tcf7 Ensembl NCBI MGI UniProt Show fit	transcription factor 7, T cell specific
chr7_-_44181477 Show fit	8.22	ENSMUST00000098483.9 ENSMUST00000035323.6	Spib Ensembl NCBI MGI UniProt Show fit	Spi-B transcription factor (Spi-1/PU.1 related)
chrX_-_100310959 Show fit	8.05	ENSMUST00000135038.2	Il2rg Ensembl NCBI MGI UniProt Show fit	interleukin 2 receptor, gamma chain
chr19_-_46033353 Show fit	7.97	ENSMUST00000026252.14 ENSMUST00000156585.9 ENSMUST00000185355.7 ENSMUST00000152946.8	Ldb1 Ensembl NCBI MGI UniProt Show fit	LIM domain binding 1
chr6_+_41520379 Show fit	7.84	ENSMUST00000103297.2	Trbj2-5 Ensembl NCBI MGI UniProt Show fit	T cell receptor beta joining 2-5
chr16_-_36486429 Show fit	7.69	ENSMUST00000089620.11	Cd86 Ensembl NCBI MGI UniProt Show fit	CD86 antigen
chr6_+_41519884 Show fit	7.56	ENSMUST00000103294.2	Trbj2-2 Ensembl NCBI MGI UniProt Show fit	T cell receptor beta joining 2-2
chr16_-_19019100 Show fit	7.42	ENSMUST00000103749.3	Iglc2 Ensembl NCBI MGI UniProt Show fit	immunoglobulin lambda constant 2
chr6_+_41520287 Show fit	7.33	ENSMUST00000103296.2	Trbj2-4 Ensembl NCBI MGI UniProt Show fit	T cell receptor beta joining 2-4
chr7_-_126736979 Show fit	7.30	ENSMUST00000049931.6	Spn Ensembl NCBI MGI UniProt Show fit	sialophorin
chr10_+_79852487 Show fit	7.22	ENSMUST00000099501.10	Arhgap45 Ensembl NCBI MGI UniProt Show fit	Rho GTPase activating protein 45
chr10_+_79852750 Show fit	6.99	ENSMUST00000105373.8	Arhgap45 Ensembl NCBI MGI UniProt Show fit	Rho GTPase activating protein 45
chr12_+_24758968 Show fit	6.89	ENSMUST00000154588.2	Rrm2 Ensembl NCBI MGI UniProt Show fit	ribonucleotide reductase M2
chr19_-_9065309 Show fit	6.77	ENSMUST00000025554.3	Scgb1a1 Ensembl NCBI MGI UniProt Show fit	secretoglobin, family 1A, member 1 (uteroglobin)
chr1_+_61017057 Show fit	6.69	ENSMUST00000027162.12 ENSMUST00000102827.4	Icos Ensembl NCBI MGI UniProt Show fit	inducible T cell co-stimulator
chr4_+_138503046 Show fit	6.68	ENSMUST00000030528.9	Pla2g2d Ensembl NCBI MGI UniProt Show fit	phospholipase A2, group IID
chr7_+_43057611 Show fit	6.63	ENSMUST00000005592.7	Siglecg Ensembl NCBI MGI UniProt Show fit	sialic acid binding Ig-like lectin G
chr12_-_113324852 Show fit	6.29	ENSMUST00000223179.2 ENSMUST00000103423.3	Ighg3 Ensembl NCBI MGI UniProt Show fit	Immunoglobulin heavy constant gamma 3
chr19_-_4241034 Show fit	6.24	ENSMUST00000237495.2	Tbc1d10c Ensembl NCBI MGI UniProt Show fit	TBC1 domain family, member 10c
chr16_+_48692976 Show fit	6.21	ENSMUST00000065666.6	Retnlg Ensembl NCBI MGI UniProt Show fit	resistin like gamma
chr11_+_106642052 Show fit	6.18	ENSMUST00000147326.9 ENSMUST00000182896.8 ENSMUST00000182908.8 ENSMUST00000086353.11	Milr1 Ensembl NCBI MGI UniProt Show fit	mast cell immunoglobulin like receptor 1
chr19_-_4240984 Show fit	6.13	ENSMUST00000045864.4	Tbc1d10c Ensembl NCBI MGI UniProt Show fit	TBC1 domain family, member 10c
chr11_+_95728042 Show fit	6.13	ENSMUST00000107712.8	Gngt2 Ensembl NCBI MGI UniProt Show fit	guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2
chr5_-_137856280 Show fit	6.08	ENSMUST00000110978.7 ENSMUST00000199387.2 ENSMUST00000196195.2	Pilrb1 Ensembl NCBI MGI UniProt Show fit	paired immunoglobin-like type 2 receptor beta 1
chr4_-_129452148 Show fit	6.04	ENSMUST00000167288.8 ENSMUST00000134336.3	Lck Ensembl NCBI MGI UniProt Show fit	lymphocyte protein tyrosine kinase
chr2_-_126341757 Show fit	6.02	ENSMUST00000040128.12	Atp8b4 Ensembl NCBI MGI UniProt Show fit	ATPase, class I, type 8B, member 4
chr4_-_129452180 Show fit	5.99	ENSMUST00000067240.11	Lck Ensembl NCBI MGI UniProt Show fit	lymphocyte protein tyrosine kinase
chr6_+_117145496 Show fit	5.90	ENSMUST00000112866.8 ENSMUST00000112871.8 ENSMUST00000073043.5	Cxcl12 Ensembl NCBI MGI UniProt Show fit	chemokine (C-X-C motif) ligand 12
chr12_-_113552322 Show fit	5.85	ENSMUST00000103443.3	Ighv2-2 Ensembl NCBI MGI UniProt Show fit	immunoglobulin heavy variable 2-2
chr15_-_97629209 Show fit	5.59	ENSMUST00000100249.10	Endou Ensembl NCBI MGI UniProt Show fit	endonuclease, polyU-specific
chr3_+_87283687 Show fit	5.56	ENSMUST00000163661.8 ENSMUST00000072480.9	Fcrl1 Ensembl NCBI MGI UniProt Show fit	Fc receptor-like 1
chr7_+_28136861 Show fit	5.55	ENSMUST00000108292.9 ENSMUST00000108289.8	Gmfg Ensembl NCBI MGI UniProt Show fit	glia maturation factor, gamma
chr16_+_49675682 Show fit	5.50	ENSMUST00000114496.3	Cd47 Ensembl NCBI MGI UniProt Show fit	CD47 antigen (Rh-related antigen, integrin-associated signal transducer)
chr1_+_172327569 Show fit	5.45	ENSMUST00000111230.8	Tagln2 Ensembl NCBI MGI UniProt Show fit	transgelin 2
chr8_+_13087805 Show fit	5.40	ENSMUST00000128418.8 ENSMUST00000152034.2	F10 Ensembl NCBI MGI UniProt Show fit	coagulation factor X
chr8_+_81220410 Show fit	5.38	ENSMUST00000063359.8	Gypa Ensembl NCBI MGI UniProt Show fit	glycophorin A
chr1_-_45964730 Show fit	5.30	ENSMUST00000027137.11	Slc40a1 Ensembl NCBI MGI UniProt Show fit	solute carrier family 40 (iron-regulated transporter), member 1
chr9_+_7764042 Show fit	5.29	ENSMUST00000052865.16	Tmem123 Ensembl NCBI MGI UniProt Show fit	transmembrane protein 123
chr16_+_49675969 Show fit	5.29	ENSMUST00000229101.2 ENSMUST00000230836.2 ENSMUST00000229206.2 ENSMUST00000084838.14 ENSMUST00000230281.2	Cd47 Ensembl NCBI MGI UniProt Show fit	CD47 antigen (Rh-related antigen, integrin-associated signal transducer)
chr19_+_6451667 Show fit	5.28	ENSMUST00000113471.3 ENSMUST00000113469.3	Rasgrp2 Ensembl NCBI MGI UniProt Show fit	RAS, guanyl releasing protein 2
chr11_+_106642079 Show fit	5.21	ENSMUST00000183111.8 ENSMUST00000106794.9	Milr1 Ensembl NCBI MGI UniProt Show fit	mast cell immunoglobulin like receptor 1
chr16_+_49676130 Show fit	5.18	ENSMUST00000230641.2	Cd47 Ensembl NCBI MGI UniProt Show fit	CD47 antigen (Rh-related antigen, integrin-associated signal transducer)
chrX_+_73314418 Show fit	5.17	ENSMUST00000008826.14 ENSMUST00000151702.8 ENSMUST00000074085.12 ENSMUST00000135690.2	Rpl10 Ensembl NCBI MGI UniProt Show fit	ribosomal protein L10
chr5_-_137834470 Show fit	5.12	ENSMUST00000110980.2 ENSMUST00000058897.11 ENSMUST00000199028.2	Pilra Ensembl NCBI MGI UniProt Show fit	paired immunoglobin-like type 2 receptor alpha
chr12_+_24758240 Show fit	5.10	ENSMUST00000020980.12	Rrm2 Ensembl NCBI MGI UniProt Show fit	ribonucleotide reductase M2
chr10_-_60055082 Show fit	5.01	ENSMUST00000135158.9	Chst3 Ensembl NCBI MGI UniProt Show fit	carbohydrate sulfotransferase 3
chr12_+_24758724 Show fit	4.97	ENSMUST00000153058.8	Rrm2 Ensembl NCBI MGI UniProt Show fit	ribonucleotide reductase M2
chr1_+_172327812 Show fit	4.97	ENSMUST00000192460.2	Tagln2 Ensembl NCBI MGI UniProt Show fit	transgelin 2
chr10_+_79824418 Show fit	4.95	ENSMUST00000004784.11 ENSMUST00000105374.2	Cnn2 Ensembl NCBI MGI UniProt Show fit	calponin 2
chr2_-_118377500 Show fit	4.91	ENSMUST00000125860.3	Bmf Ensembl NCBI MGI UniProt Show fit	BCL2 modifying factor
chr10_+_43455157 Show fit	4.88	ENSMUST00000058714.10	Cd24a Ensembl NCBI MGI UniProt Show fit	CD24a antigen
chr8_-_25592385 Show fit	4.78	ENSMUST00000064883.14	Plekha2 Ensembl NCBI MGI UniProt Show fit	pleckstrin homology domain-containing, family A (phosphoinositide binding specific) member 2
chr3_-_9898713 Show fit	4.76	ENSMUST00000161949.8	Pag1 Ensembl NCBI MGI UniProt Show fit	phosphoprotein associated with glycosphingolipid microdomains 1
chr8_+_84682136 Show fit	4.67	ENSMUST00000005607.9	Asf1b Ensembl NCBI MGI UniProt Show fit	anti-silencing function 1B histone chaperone
chr17_+_8454939 Show fit	4.65	ENSMUST00000164411.10	Ccr6 Ensembl NCBI MGI UniProt Show fit	chemokine (C-C motif) receptor 6
chr17_+_18108102 Show fit	4.65	ENSMUST00000054871.12 ENSMUST00000064068.5	Fpr3 Ensembl NCBI MGI UniProt Show fit Fpr2 Ensembl NCBI MGI UniProt Show fit	formyl peptide receptor 3 formyl peptide receptor 2
chr7_+_101034604 Show fit	4.63	ENSMUST00000130016.8 ENSMUST00000134143.2	Arap1 Ensembl NCBI MGI UniProt Show fit	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chr3_+_87283767 Show fit	4.60	ENSMUST00000194786.6 ENSMUST00000191666.2	Fcrl1 Ensembl NCBI MGI UniProt Show fit	Fc receptor-like 1
chr12_+_98234884 Show fit	4.60	ENSMUST00000075072.6	Gpr65 Ensembl NCBI MGI UniProt Show fit	G-protein coupled receptor 65
chr17_+_18108086 Show fit	4.56	ENSMUST00000149944.2	Fpr2 Ensembl NCBI MGI UniProt Show fit	formyl peptide receptor 2
chr17_-_74257164 Show fit	4.51	ENSMUST00000024866.6	Xdh Ensembl NCBI MGI UniProt Show fit	xanthine dehydrogenase
chr15_-_100585789 Show fit	4.47	ENSMUST00000023775.9	Cela1 Ensembl NCBI MGI UniProt Show fit	chymotrypsin-like elastase family, member 1
chr2_+_164897547 Show fit	4.46	ENSMUST00000017799.12 ENSMUST00000073707.9	Cd40 Ensembl NCBI MGI UniProt Show fit	CD40 antigen
chr3_+_87283748 Show fit	4.40	ENSMUST00000167200.7	Fcrl1 Ensembl NCBI MGI UniProt Show fit	Fc receptor-like 1
chr2_+_164897583 Show fit	4.35	ENSMUST00000081310.11 ENSMUST00000140951.8	Cd40 Ensembl NCBI MGI UniProt Show fit	CD40 antigen
chr15_+_75468473 Show fit	4.35	ENSMUST00000189944.7 ENSMUST00000023243.11	Gpihbp1 Ensembl NCBI MGI UniProt Show fit	GPI-anchored HDL-binding protein 1
chr8_+_66070661 Show fit	4.32	ENSMUST00000110258.8 ENSMUST00000110256.8 ENSMUST00000110255.8	Marchf1 Ensembl NCBI MGI UniProt Show fit	membrane associated ring-CH-type finger 1
chr11_+_115353290 Show fit	4.27	ENSMUST00000106532.4 ENSMUST00000092445.12 ENSMUST00000153466.2	Slc16a5 Ensembl NCBI MGI UniProt Show fit	solute carrier family 16 (monocarboxylic acid transporters), member 5
chr19_-_4213347 Show fit	4.25	ENSMUST00000025749.15	Rps6kb2 Ensembl NCBI MGI UniProt Show fit	ribosomal protein S6 kinase, polypeptide 2
chr8_-_25591737 Show fit	4.22	ENSMUST00000098866.11	Plekha2 Ensembl NCBI MGI UniProt Show fit	pleckstrin homology domain-containing, family A (phosphoinositide binding specific) member 2
chr1_+_34511793 Show fit	4.22	ENSMUST00000188972.3	Ptpn18 Ensembl NCBI MGI UniProt Show fit	protein tyrosine phosphatase, non-receptor type 18
chr18_+_60509101 Show fit	4.13	ENSMUST00000032473.7 ENSMUST00000066912.13	Iigp1 Ensembl NCBI MGI UniProt Show fit	interferon inducible GTPase 1
chr11_+_115790768 Show fit	4.09	ENSMUST00000152171.8	Smim5 Ensembl NCBI MGI UniProt Show fit	small integral membrane protein 5
chr16_-_19525122 Show fit	4.06	ENSMUST00000081880.7	Lamp3 Ensembl NCBI MGI UniProt Show fit	lysosomal-associated membrane protein 3
chr1_-_80642969 Show fit	4.05	ENSMUST00000190983.7 ENSMUST00000191449.2	Dock10 Ensembl NCBI MGI UniProt Show fit	dedicator of cytokinesis 10
chr2_-_117173312 Show fit	4.02	ENSMUST00000178884.8	Rasgrp1 Ensembl NCBI MGI UniProt Show fit	RAS guanyl releasing protein 1
chr5_-_105491795 Show fit	4.01	ENSMUST00000171587.2	Gbp11 Ensembl NCBI MGI UniProt Show fit	guanylate binding protein 11
chr13_-_49473695 Show fit	4.00	ENSMUST00000110086.2	Fgd3 Ensembl NCBI MGI UniProt Show fit	FYVE, RhoGEF and PH domain containing 3
chr16_+_44586085 Show fit	3.97	ENSMUST00000057488.15	Cd200r1 Ensembl NCBI MGI UniProt Show fit	CD200 receptor 1
chr10_-_62343516 Show fit	3.96	ENSMUST00000020271.13	Srgn Ensembl NCBI MGI UniProt Show fit	serglycin
chr1_-_36312482 Show fit	3.93	ENSMUST00000056946.8	Neurl3 Ensembl NCBI MGI UniProt Show fit	neuralized E3 ubiquitin protein ligase 3
chr14_+_53791444 Show fit	3.91	ENSMUST00000198297.2	Trav14-1 Ensembl NCBI MGI UniProt Show fit	T cell receptor alpha variable 14-1
chr1_+_34498836 Show fit	3.91	ENSMUST00000027302.14 ENSMUST00000190122.2	Ptpn18 Ensembl NCBI MGI UniProt Show fit	protein tyrosine phosphatase, non-receptor type 18
chr2_-_117173428 Show fit	3.85	ENSMUST00000102534.11	Rasgrp1 Ensembl NCBI MGI UniProt Show fit	RAS guanyl releasing protein 1
chr8_-_106660470 Show fit	3.83	ENSMUST00000034368.8	Ctrl Ensembl NCBI MGI UniProt Show fit	chymotrypsin-like
chr4_-_63779562 Show fit	3.81	ENSMUST00000030047.3	Tnfsf8 Ensembl NCBI MGI UniProt Show fit	tumor necrosis factor (ligand) superfamily, member 8
chr2_+_127967951 Show fit	3.79	ENSMUST00000089634.12 ENSMUST00000019281.14 ENSMUST00000110341.9 ENSMUST00000103211.8 ENSMUST00000103210.2	Bcl2l11 Ensembl NCBI MGI UniProt Show fit	BCL2-like 11 (apoptosis facilitator)
chrX_+_99669343 Show fit	3.78	ENSMUST00000048962.4	Kif4 Ensembl NCBI MGI UniProt Show fit	kinesin family member 4
chr10_+_79722081 Show fit	3.75	ENSMUST00000046091.7	Elane Ensembl NCBI MGI UniProt Show fit	elastase, neutrophil expressed
chr10_+_98943999 Show fit	3.73	ENSMUST00000161240.4	Galnt4 Ensembl NCBI MGI UniProt Show fit	polypeptide N-acetylgalactosaminyltransferase 4
chr7_-_46365108 Show fit	3.69	ENSMUST00000006956.9 ENSMUST00000210913.2	Saa3 Ensembl NCBI MGI UniProt Show fit	serum amyloid A 3
chr2_+_84818538 Show fit	3.67	ENSMUST00000028466.12	Prg3 Ensembl NCBI MGI UniProt Show fit	proteoglycan 3
chr3_+_103767581 Show fit	3.64	ENSMUST00000029433.9	Ptpn22 Ensembl NCBI MGI UniProt Show fit	protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
chr14_+_53941464 Show fit	3.61	ENSMUST00000103664.6	Trav5-4 Ensembl NCBI MGI UniProt Show fit	T cell receptor alpha variable 5-4
chr2_-_117173190 Show fit	3.59	ENSMUST00000173541.8 ENSMUST00000172901.8 ENSMUST00000173252.2	Rasgrp1 Ensembl NCBI MGI UniProt Show fit	RAS guanyl releasing protein 1
chr14_+_54444554 Show fit	3.58	ENSMUST00000103730.2	Traj11 Ensembl NCBI MGI UniProt Show fit	T cell receptor alpha joining 11
chr14_+_53859114 Show fit	3.57	ENSMUST00000103657.6	Trav12-3 Ensembl NCBI MGI UniProt Show fit	T cell receptor alpha variable 12-3
chr17_-_31363245 Show fit	3.55	ENSMUST00000024826.8	Tff2 Ensembl NCBI MGI UniProt Show fit	trefoil factor 2 (spasmolytic protein 1)
chr17_+_8454862 Show fit	3.55	ENSMUST00000231340.2	Ccr6 Ensembl NCBI MGI UniProt Show fit	chemokine (C-C motif) receptor 6
chr6_-_99497900 Show fit	3.54	ENSMUST00000176565.8	Foxp1 Ensembl NCBI MGI UniProt Show fit	forkhead box P1
chr3_-_9898676 Show fit	3.53	ENSMUST00000108384.9	Pag1 Ensembl NCBI MGI UniProt Show fit	phosphoprotein associated with glycosphingolipid microdomains 1
chr19_-_7218363 Show fit	3.50	ENSMUST00000236769.2	Naa40 Ensembl NCBI MGI UniProt Show fit	N(alpha)-acetyltransferase 40, NatD catalytic subunit
chrX_+_158491589 Show fit	3.47	ENSMUST00000080394.13	Sh3kbp1 Ensembl NCBI MGI UniProt Show fit	SH3-domain kinase binding protein 1
chr14_+_53059379 Show fit	3.43	ENSMUST00000197754.2	Trav6d-6 Ensembl NCBI MGI UniProt Show fit	T cell receptor alpha variable 6D-6
chr3_-_59038634 Show fit	3.42	ENSMUST00000200358.2 ENSMUST00000197220.2	P2ry14 Ensembl NCBI MGI UniProt Show fit	purinergic receptor P2Y, G-protein coupled, 14
chr17_+_34816826 Show fit	3.41	ENSMUST00000015596.10 ENSMUST00000174496.9 ENSMUST00000173992.8	Ager Ensembl NCBI MGI UniProt Show fit	advanced glycosylation end product-specific receptor
chr7_+_82297803 Show fit	3.40	ENSMUST00000141726.8 ENSMUST00000179489.8 ENSMUST00000039881.4	Efl1 Ensembl NCBI MGI UniProt Show fit	elongation factor like GTPase 1
chr13_-_19521337 Show fit	3.39	ENSMUST00000103563.3	Trgv2 Ensembl NCBI MGI UniProt Show fit	T cell receptor gamma variable 2
chr9_+_107957621 Show fit	3.36	ENSMUST00000035211.14	Mst1 Ensembl NCBI MGI UniProt Show fit	macrophage stimulating 1 (hepatocyte growth factor-like)
chr6_-_70149254 Show fit	3.33	ENSMUST00000197272.2	Igkv8-27 Ensembl NCBI MGI UniProt Show fit	immunoglobulin kappa chain variable 8-27
chr11_+_115790951 Show fit	3.29	ENSMUST00000142089.2 ENSMUST00000131566.2	Smim5 Ensembl NCBI MGI UniProt Show fit	small integral membrane protein 5
chr14_+_53698556 Show fit	3.29	ENSMUST00000181728.3	Trav7-4 Ensembl NCBI MGI UniProt Show fit	T cell receptor alpha variable 7-4
chr14_+_54394723 Show fit	3.28	ENSMUST00000103687.2	Traj58 Ensembl NCBI MGI UniProt Show fit	T cell receptor alpha joining 58
chr9_+_123902143 Show fit	3.25	ENSMUST00000168841.3 ENSMUST00000055918.7	Ccr2 Ensembl NCBI MGI UniProt Show fit	chemokine (C-C motif) receptor 2
chr14_-_55950939 Show fit	3.21	ENSMUST00000168729.8 ENSMUST00000228123.2 ENSMUST00000178034.9	Tgm1 Ensembl NCBI MGI UniProt Show fit	transglutaminase 1, K polypeptide
chr13_+_19524136 Show fit	3.21	ENSMUST00000103564.3	Trgv1 Ensembl NCBI MGI UniProt Show fit	T cell receptor gamma, variable 1
chr12_-_32000534 Show fit	3.19	ENSMUST00000172314.9	Hbp1 Ensembl NCBI MGI UniProt Show fit	high mobility group box transcription factor 1
chr14_-_54386718 Show fit	3.18	ENSMUST00000103685.3	Trdv5 Ensembl NCBI MGI UniProt Show fit	T cell receptor delta variable 5
chr5_+_108048367 Show fit	3.14	ENSMUST00000082223.13	Rpl5 Ensembl NCBI MGI UniProt Show fit	ribosomal protein L5
chr17_+_87590308 Show fit	3.13	ENSMUST00000041110.12 ENSMUST00000125875.8	Ttc7 Ensembl NCBI MGI UniProt Show fit	tetratricopeptide repeat domain 7
chr12_-_113843161 Show fit	3.13	ENSMUST00000103451.5	Ighv2-9 Ensembl NCBI MGI UniProt Show fit	immunoglobulin heavy variable 2-9
chr1_-_80643024 Show fit	3.12	ENSMUST00000187774.7	Dock10 Ensembl NCBI MGI UniProt Show fit	dedicator of cytokinesis 10
chr6_-_41681273 Show fit	3.11	ENSMUST00000031899.14	Kel Ensembl NCBI MGI UniProt Show fit	Kell blood group
chr6_+_67838100 Show fit	3.10	ENSMUST00000200586.2 ENSMUST00000103309.3	Igkv17-127 Ensembl NCBI MGI UniProt Show fit	immunoglobulin kappa variable 17-127
chr15_-_74599860 Show fit	3.10	ENSMUST00000023261.4 ENSMUST00000190433.2	Slurp1 Ensembl NCBI MGI UniProt Show fit	secreted Ly6/Plaur domain containing 1
chr6_-_99243455 Show fit	3.09	ENSMUST00000113326.9	Foxp1 Ensembl NCBI MGI UniProt Show fit	forkhead box P1
chr12_+_102249294 Show fit	3.08	ENSMUST00000056950.14	Rin3 Ensembl NCBI MGI UniProt Show fit	Ras and Rab interactor 3
chr5_+_108048697 Show fit	3.08	ENSMUST00000153590.2	Rpl5 Ensembl NCBI MGI UniProt Show fit	ribosomal protein L5
chr5_-_137834444 Show fit	3.07	ENSMUST00000197586.2	Pilra Ensembl NCBI MGI UniProt Show fit	paired immunoglobin-like type 2 receptor alpha
chr19_-_11301919 Show fit	3.06	ENSMUST00000159269.2	Ms4a7 Ensembl NCBI MGI UniProt Show fit	membrane-spanning 4-domains, subfamily A, member 7
chr17_-_52140305 Show fit	3.04	ENSMUST00000133574.8	Satb1 Ensembl NCBI MGI UniProt Show fit	special AT-rich sequence binding protein 1
chr9_-_108888284 Show fit	3.03	ENSMUST00000112053.2	Trex1 Ensembl NCBI MGI UniProt Show fit	three prime repair exonuclease 1
chr3_+_68912043 Show fit	3.02	ENSMUST00000042901.15	Smc4 Ensembl NCBI MGI UniProt Show fit	structural maintenance of chromosomes 4
chr6_+_129022843 Show fit	3.00	ENSMUST00000032257.10 ENSMUST00000204320.2	Klrb1f Ensembl NCBI MGI UniProt Show fit	killer cell lectin-like receptor subfamily B member 1F
chr11_-_106051533 Show fit	2.96	ENSMUST00000106875.2	Limd2 Ensembl NCBI MGI UniProt Show fit	LIM domain containing 2
chr2_-_129139125 Show fit	2.93	ENSMUST00000052708.7	Ckap2l Ensembl NCBI MGI UniProt Show fit	cytoskeleton associated protein 2-like
chrX_-_36253309 Show fit	2.91	ENSMUST00000060474.14 ENSMUST00000053456.11 ENSMUST00000115239.10	Septin6 Ensembl NCBI MGI UniProt Show fit	septin 6
chr3_-_20089433 Show fit	2.88	ENSMUST00000108321.2 ENSMUST00000012580.13	Hps3 Ensembl NCBI MGI UniProt Show fit	HPS3, biogenesis of lysosomal organelles complex 2 subunit 1
chr3_-_36529753 Show fit	2.86	ENSMUST00000199478.2	Anxa5 Ensembl NCBI MGI UniProt Show fit	annexin A5
chr15_-_34443054 Show fit	2.86	ENSMUST00000142643.2	Rpl30 Ensembl NCBI MGI UniProt Show fit	ribosomal protein L30
chr3_-_96201248 Show fit	2.86	ENSMUST00000029748.8	Fcgr1 Ensembl NCBI MGI UniProt Show fit	Fc receptor, IgG, high affinity I
chr11_-_78875689 Show fit	2.86	ENSMUST00000108269.10 ENSMUST00000108268.10	Lgals9 Ensembl NCBI MGI UniProt Show fit	lectin, galactose binding, soluble 9
chr13_+_102830029 Show fit	2.85	ENSMUST00000022124.10 ENSMUST00000171267.2 ENSMUST00000167144.2 ENSMUST00000170878.2	Cd180 Ensembl NCBI MGI UniProt Show fit	CD180 antigen
chr14_+_32507920 Show fit	2.85	ENSMUST00000039191.8 ENSMUST00000227060.2 ENSMUST00000228481.2	Tmem273 Ensembl NCBI MGI UniProt Show fit	transmembrane protein 273
chr2_+_180098026 Show fit	2.84	ENSMUST00000038259.13	Slco4a1 Ensembl NCBI MGI UniProt Show fit	solute carrier organic anion transporter family, member 4a1
chr9_+_107957640 Show fit	2.82	ENSMUST00000162886.2	Mst1 Ensembl NCBI MGI UniProt Show fit	macrophage stimulating 1 (hepatocyte growth factor-like)
chr16_+_91184661 Show fit	2.81	ENSMUST00000139503.2	Ifnar2 Ensembl NCBI MGI UniProt Show fit	interferon (alpha and beta) receptor 2
chr6_+_38895902 Show fit	2.80	ENSMUST00000003017.13	Tbxas1 Ensembl NCBI MGI UniProt Show fit	thromboxane A synthase 1, platelet
chr14_+_54444010 Show fit	2.80	ENSMUST00000103729.2	Traj12 Ensembl NCBI MGI UniProt Show fit	T cell receptor alpha joining 12
chr19_-_4251589 Show fit	2.78	ENSMUST00000237923.2 ENSMUST00000025740.8 ENSMUST00000237723.2	Rad9a Ensembl NCBI MGI UniProt Show fit	RAD9 checkpoint clamp component A
chr16_-_3535940 Show fit	2.76	ENSMUST00000229725.2 ENSMUST00000100222.4	Mefv Ensembl NCBI MGI UniProt Show fit	Mediterranean fever
chr10_+_79715448 Show fit	2.76	ENSMUST00000006679.15	Prtn3 Ensembl NCBI MGI UniProt Show fit	proteinase 3
chr7_+_30122685 Show fit	2.75	ENSMUST00000046177.9	Nfkbid Ensembl NCBI MGI UniProt Show fit	nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, delta
chr15_+_103148824 Show fit	2.72	ENSMUST00000036004.16 ENSMUST00000087351.9 ENSMUST00000231141.2	Hnrnpa1 Ensembl NCBI MGI UniProt Show fit	heterogeneous nuclear ribonucleoprotein A1
chr6_+_38918327 Show fit	2.70	ENSMUST00000160963.2	Tbxas1 Ensembl NCBI MGI UniProt Show fit	thromboxane A synthase 1, platelet
chr14_+_45225641 Show fit	2.69	ENSMUST00000046891.6	Ptger2 Ensembl NCBI MGI UniProt Show fit	prostaglandin E receptor 2 (subtype EP2)
chr4_+_137944546 Show fit	2.69	ENSMUST00000130071.2	Hp1bp3 Ensembl NCBI MGI UniProt Show fit	heterochromatin protein 1, binding protein 3
chr5_+_45827249 Show fit	2.66	ENSMUST00000117396.3	Ncapg Ensembl NCBI MGI UniProt Show fit	non-SMC condensin I complex, subunit G
chr8_+_67947494 Show fit	2.64	ENSMUST00000093470.7 ENSMUST00000163856.3	Nat2 Ensembl NCBI MGI UniProt Show fit	N-acetyltransferase 2 (arylamine N-acetyltransferase)
chr6_+_78382131 Show fit	2.64	ENSMUST00000023906.4	Reg2 Ensembl NCBI MGI UniProt Show fit	regenerating islet-derived 2
chr11_+_101333238 Show fit	2.61	ENSMUST00000107249.8	Rpl27 Ensembl NCBI MGI UniProt Show fit	ribosomal protein L27
chr14_+_54701594 Show fit	2.59	ENSMUST00000022782.10	Lrp10 Ensembl NCBI MGI UniProt Show fit	low-density lipoprotein receptor-related protein 10
chr11_-_75918551 Show fit	2.55	ENSMUST00000021207.7	Rflnb Ensembl NCBI MGI UniProt Show fit	refilin B
chr19_+_6108240 Show fit	2.55	ENSMUST00000237840.2	Fau Ensembl NCBI MGI UniProt Show fit	Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed (fox derived)
chr16_-_3535958 Show fit	2.54	ENSMUST00000023180.15	Mefv Ensembl NCBI MGI UniProt Show fit	Mediterranean fever
chr3_-_92577621 Show fit	2.53	ENSMUST00000029530.6	Lce1a2 Ensembl NCBI MGI UniProt Show fit	late cornified envelope 1A2
chr4_+_130253925 Show fit	2.53	ENSMUST00000105994.4	Snrnp40 Ensembl NCBI MGI UniProt Show fit	small nuclear ribonucleoprotein 40 (U5)
chr11_-_78875657 Show fit	2.53	ENSMUST00000073001.5	Lgals9 Ensembl NCBI MGI UniProt Show fit	lectin, galactose binding, soluble 9
chr11_+_101333115 Show fit	2.51	ENSMUST00000077856.13	Rpl27 Ensembl NCBI MGI UniProt Show fit	ribosomal protein L27
chr3_-_59038160 Show fit	2.51	ENSMUST00000197841.2	P2ry14 Ensembl NCBI MGI UniProt Show fit	purinergic receptor P2Y, G-protein coupled, 14
chr16_+_87495792 Show fit	2.51	ENSMUST00000026703.6	Bach1 Ensembl NCBI MGI UniProt Show fit	BTB and CNC homology 1, basic leucine zipper transcription factor 1
chr6_-_72367642 Show fit	2.51	ENSMUST00000059983.10	Vamp8 Ensembl NCBI MGI UniProt Show fit	vesicle-associated membrane protein 8
chr11_+_44290884 Show fit	2.50	ENSMUST00000170513.3 ENSMUST00000102796.10	Il12b Ensembl NCBI MGI UniProt Show fit	interleukin 12b
chr8_-_106863521 Show fit	2.48	ENSMUST00000115979.9	Esrp2 Ensembl NCBI MGI UniProt Show fit	epithelial splicing regulatory protein 2
chr7_+_78563964 Show fit	2.48	ENSMUST00000120331.4	Isg20 Ensembl NCBI MGI UniProt Show fit	interferon-stimulated protein
chr13_-_20008397 Show fit	2.43	ENSMUST00000222664.2 ENSMUST00000065335.3	Gpr141 Ensembl NCBI MGI UniProt Show fit	G protein-coupled receptor 141
chr11_-_5848771 Show fit	2.42	ENSMUST00000102921.4	Myl7 Ensembl NCBI MGI UniProt Show fit	myosin, light polypeptide 7, regulatory
chr1_-_162726234 Show fit	2.40	ENSMUST00000111510.8 ENSMUST00000045902.13	Fmo2 Ensembl NCBI MGI UniProt Show fit	flavin containing monooxygenase 2
chr11_+_68936457 Show fit	2.39	ENSMUST00000108666.8 ENSMUST00000021277.6	Aurkb Ensembl NCBI MGI UniProt Show fit	aurora kinase B
chr19_-_7218512 Show fit	2.39	ENSMUST00000025675.11	Naa40 Ensembl NCBI MGI UniProt Show fit	N(alpha)-acetyltransferase 40, NatD catalytic subunit
chr1_-_91340884 Show fit	2.37	ENSMUST00000086851.2	Hes6 Ensembl NCBI MGI UniProt Show fit	hairy and enhancer of split 6
chr4_+_63274388 Show fit	2.35	ENSMUST00000006687.5	Orm3 Ensembl NCBI MGI UniProt Show fit	orosomucoid 3
chr3_+_92874366 Show fit	2.35	ENSMUST00000098886.5	Lce3e Ensembl NCBI MGI UniProt Show fit	late cornified envelope 3E
chr9_+_94551929 Show fit	2.35	ENSMUST00000033463.10	Slc9a9 Ensembl NCBI MGI UniProt Show fit	solute carrier family 9 (sodium/hydrogen exchanger), member 9
chr12_-_32000169 Show fit	2.34	ENSMUST00000176520.8	Hbp1 Ensembl NCBI MGI UniProt Show fit	high mobility group box transcription factor 1
chr10_-_34083570 Show fit	2.33	ENSMUST00000215547.2 ENSMUST00000048010.9	Dse Ensembl NCBI MGI UniProt Show fit	dermatan sulfate epimerase
chr14_+_53954133 Show fit	2.32	ENSMUST00000103641.6	Trav7-6 Ensembl NCBI MGI UniProt Show fit	T cell receptor alpha variable 7-6
chr11_-_99501015 Show fit	2.32	ENSMUST00000076478.2	Gm11937 Ensembl NCBI MGI UniProt Show fit	predicted gene 11937
chr7_-_112987770 Show fit	2.31	ENSMUST00000079793.7	Pth Ensembl NCBI MGI UniProt Show fit	parathyroid hormone
chr4_+_137944438 Show fit	2.30	ENSMUST00000137851.8 ENSMUST00000165861.8	Hp1bp3 Ensembl NCBI MGI UniProt Show fit	heterochromatin protein 1, binding protein 3
chr1_+_172302925 Show fit	2.29	ENSMUST00000027830.5	Slamf9 Ensembl NCBI MGI UniProt Show fit	SLAM family member 9
chr6_+_68657317 Show fit	2.28	ENSMUST00000198735.2	Igkv10-95 Ensembl NCBI MGI UniProt Show fit	immunoglobulin kappa variable 10-95
chr8_-_106863423 Show fit	2.28	ENSMUST00000146940.2	Esrp2 Ensembl NCBI MGI UniProt Show fit	epithelial splicing regulatory protein 2
chrX_-_50294867 Show fit	2.27	ENSMUST00000114876.9	Mbnl3 Ensembl NCBI MGI UniProt Show fit	muscleblind like splicing factor 3

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
5.1	20.3	GO:0070488	neutrophil aggregation(GO:0070488)
2.7	8.2	GO:1904155	DN2 thymocyte differentiation(GO:1904155) DN3 thymocyte differentiation(GO:1904156)
2.7	8.0	GO:0043973	histone H3-K4 acetylation(GO:0043973)
2.4	7.3	GO:0001807	regulation of type IV hypersensitivity(GO:0001807)
2.1	6.2	GO:0090320	regulation of chylomicron remnant clearance(GO:0090320)
2.1	6.2	GO:1903632	positive regulation of aminoacyl-tRNA ligase activity(GO:1903632)
1.9	5.6	GO:0071846	actin filament debranching(GO:0071846)
1.8	3.6	GO:1902523	positive regulation of protein K63-linked ubiquitination(GO:1902523)
1.8	5.3	GO:0070839	divalent metal ion export(GO:0070839)
1.7	6.8	GO:0032696	negative regulation of interleukin-13 production(GO:0032696)
1.6	4.9	GO:1904092	regulation of autophagic cell death(GO:1904092) negative regulation of autophagic cell death(GO:1904093)
1.6	4.9	GO:0034118	erythrocyte aggregation(GO:0034117) regulation of erythrocyte aggregation(GO:0034118)
1.6	4.8	GO:0071640	regulation of macrophage inflammatory protein 1 alpha production(GO:0071640)
1.6	14.3	GO:0051534	negative regulation of NFAT protein import into nucleus(GO:0051534)
1.6	6.2	GO:0002408	myeloid dendritic cell chemotaxis(GO:0002408)
1.5	4.6	GO:2000451	immune complex clearance by monocytes and macrophages(GO:0002436) regulation of immune complex clearance by monocytes and macrophages(GO:0090264) positive regulation of immune complex clearance by monocytes and macrophages(GO:0090265) negative regulation of eosinophil activation(GO:1902567) positive regulation of CD8-positive, alpha-beta T cell extravasation(GO:2000451)
1.5	5.9	GO:1903237	negative regulation of leukocyte tethering or rolling(GO:1903237)
1.5	16.0	GO:0008228	opsonization(GO:0008228)
1.3	8.1	GO:0032831	positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032831)
1.3	9.2	GO:0002430	complement receptor mediated signaling pathway(GO:0002430)
1.3	10.3	GO:0045084	positive regulation of interleukin-12 biosynthetic process(GO:0045084)
1.2	3.7	GO:0070947	antimicrobial peptide biosynthetic process(GO:0002777) antibacterial peptide biosynthetic process(GO:0002780) neutrophil mediated killing of fungus(GO:0070947)
1.2	5.0	GO:0097298	regulation of nucleus size(GO:0097298)
1.2	4.9	GO:1900158	negative regulation of bone mineralization involved in bone maturation(GO:1900158)
1.1	3.4	GO:2001200	positive regulation of dendritic cell differentiation(GO:2001200)
1.1	10.1	GO:0035589	G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
1.1	5.4	GO:0043321	regulation of natural killer cell degranulation(GO:0043321)
1.1	8.5	GO:0002568	somatic diversification of T cell receptor genes(GO:0002568) somatic recombination of T cell receptor gene segments(GO:0002681) T cell receptor V(D)J recombination(GO:0033153)
1.1	5.3	GO:0060139	positive regulation by symbiont of host apoptotic process(GO:0052151) positive regulation of apoptotic process by virus(GO:0060139)
1.0	2.0	GO:0002649	regulation of tolerance induction to self antigen(GO:0002649)
1.0	4.0	GO:0033379	protein localization to secretory granule(GO:0033366) protein localization to mast cell secretory granule(GO:0033367) protease localization to mast cell secretory granule(GO:0033368) maintenance of protein location in mast cell secretory granule(GO:0033370) T cell secretory granule organization(GO:0033371) maintenance of protease location in mast cell secretory granule(GO:0033373) protein localization to T cell secretory granule(GO:0033374) protease localization to T cell secretory granule(GO:0033375) maintenance of protein location in T cell secretory granule(GO:0033377) maintenance of protease location in T cell secretory granule(GO:0033379) granzyme B localization to T cell secretory granule(GO:0033380) maintenance of granzyme B location in T cell secretory granule(GO:0033382)
1.0	2.9	GO:0090367	negative regulation of mRNA modification(GO:0090367)
1.0	6.7	GO:0002361	CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361)
1.0	2.9	GO:0001788	antibody-dependent cellular cytotoxicity(GO:0001788)
0.9	12.0	GO:0070474	positive regulation of uterine smooth muscle contraction(GO:0070474)
0.9	2.8	GO:0097029	mature conventional dendritic cell differentiation(GO:0097029)
0.9	3.7	GO:0045575	basophil activation(GO:0045575)
0.9	4.5	GO:0009115	xanthine catabolic process(GO:0009115)
0.9	7.9	GO:0072619	interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.9	13.9	GO:0032725	positive regulation of granulocyte macrophage colony-stimulating factor production(GO:0032725)
0.8	2.4	GO:0043988	histone H3-S28 phosphorylation(GO:0043988)
0.8	4.7	GO:0000738	DNA catabolic process, exonucleolytic(GO:0000738)
0.8	2.3	GO:0030208	dermatan sulfate biosynthetic process(GO:0030208)
0.8	3.1	GO:2000878	dipeptide transmembrane transport(GO:0035442) regulation of oligopeptide transport(GO:0090088) regulation of dipeptide transport(GO:0090089) positive regulation of oligopeptide transport(GO:2000878) positive regulation of dipeptide transport(GO:2000880) regulation of dipeptide transmembrane transport(GO:2001148) positive regulation of dipeptide transmembrane transport(GO:2001150)
0.8	14.4	GO:0002517	T cell tolerance induction(GO:0002517)
0.7	17.0	GO:0009263	deoxyribonucleotide biosynthetic process(GO:0009263)
0.7	2.9	GO:0070459	prolactin secretion(GO:0070459)
0.7	2.1	GO:0097374	sensory neuron axon guidance(GO:0097374)
0.7	2.8	GO:0060168	thiamine metabolic process(GO:0006772) thiamine-containing compound metabolic process(GO:0042723) positive regulation of adenosine receptor signaling pathway(GO:0060168)
0.7	8.8	GO:0090037	positive regulation of protein kinase C signaling(GO:0090037)
0.7	5.4	GO:0047484	regulation of response to osmotic stress(GO:0047484)
0.6	4.5	GO:0060309	elastin catabolic process(GO:0060309)
0.6	2.5	GO:0006049	UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.6	11.4	GO:0033004	negative regulation of mast cell activation(GO:0033004)
0.6	2.5	GO:0016240	autophagosome docking(GO:0016240) pancreatic amylase secretion(GO:0036395) zymogen granule exocytosis(GO:0070625) positive regulation of pancreatic juice secretion(GO:0090187) regulation of pancreatic amylase secretion(GO:1902276)
0.6	3.1	GO:0031133	regulation of axon diameter(GO:0031133)
0.6	1.8	GO:0016256	N-glycan processing to lysosome(GO:0016256)
0.6	3.6	GO:0002322	B cell proliferation involved in immune response(GO:0002322)
0.6	1.8	GO:0019427	acetate biosynthetic process(GO:0019413) acetyl-CoA biosynthetic process from acetate(GO:0019427) propionate biosynthetic process(GO:0019542)
0.6	1.8	GO:0002414	immunoglobulin transcytosis in epithelial cells(GO:0002414)
0.6	2.3	GO:0034760	negative regulation of iron ion transport(GO:0034757) negative regulation of iron ion transmembrane transport(GO:0034760)
0.6	3.4	GO:0061641	CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.6	1.7	GO:0033634	positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.6	5.0	GO:0030206	chondroitin sulfate biosynthetic process(GO:0030206)
0.5	1.6	GO:0061357	positive regulation of Wnt protein secretion(GO:0061357)
0.5	2.1	GO:0045297	mating plug formation(GO:0042628) single-organism reproductive behavior(GO:0044704) post-mating behavior(GO:0045297)
0.5	8.4	GO:0002315	marginal zone B cell differentiation(GO:0002315)
0.5	1.6	GO:0090172	attachment of spindle microtubules to kinetochore involved in homologous chromosome segregation(GO:0051455) microtubule cytoskeleton organization involved in homologous chromosome segregation(GO:0090172)
0.5	2.6	GO:0032304	negative regulation of icosanoid secretion(GO:0032304)
0.5	1.5	GO:0070175	positive regulation of enamel mineralization(GO:0070175)
0.5	4.6	GO:0060763	mammary duct terminal end bud growth(GO:0060763)
0.5	1.5	GO:0015680	intracellular copper ion transport(GO:0015680)
0.5	2.5	GO:0000117	regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.5	3.4	GO:0042256	mature ribosome assembly(GO:0042256)
0.5	2.8	GO:0090204	protein localization to nuclear pore(GO:0090204)
0.5	0.5	GO:1903630	regulation of aminoacyl-tRNA ligase activity(GO:1903630)
0.4	1.3	GO:0006285	base-excision repair, AP site formation(GO:0006285) nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296)
0.4	1.3	GO:0034473	U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476)
0.4	4.7	GO:0034723	DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.4	1.2	GO:1903334	positive regulation of protein folding(GO:1903334)
0.4	2.4	GO:0072592	oxygen metabolic process(GO:0072592)
0.4	1.5	GO:0036233	glycine import(GO:0036233)
0.4	6.8	GO:0043374	CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.4	3.8	GO:0051256	mitotic spindle midzone assembly(GO:0051256)
0.4	0.7	GO:1902569	regulation of activation of JAK2 kinase activity(GO:0010534) activation of JAK2 kinase activity(GO:0042977) negative regulation of activation of JAK2 kinase activity(GO:1902569)
0.4	7.8	GO:0010745	negative regulation of macrophage derived foam cell differentiation(GO:0010745)
0.4	2.8	GO:0070327	thyroid hormone transport(GO:0070327)
0.3	1.0	GO:0072356	chromosome passenger complex localization to kinetochore(GO:0072356)
0.3	1.4	GO:0021526	medial motor column neuron differentiation(GO:0021526)
0.3	8.2	GO:0016973	poly(A)+ mRNA export from nucleus(GO:0016973)
0.3	1.7	GO:0035752	lysosomal lumen pH elevation(GO:0035752)
0.3	1.0	GO:0051344	negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.3	3.2	GO:1903690	negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.3	1.2	GO:0061386	closure of optic fissure(GO:0061386)
0.3	1.8	GO:0007296	vitellogenesis(GO:0007296)
0.3	1.2	GO:0000390	spliceosomal complex disassembly(GO:0000390)
0.3	3.0	GO:0010032	meiotic chromosome condensation(GO:0010032)
0.3	3.6	GO:0010838	positive regulation of keratinocyte proliferation(GO:0010838)
0.3	0.9	GO:0010133	proline catabolic process to glutamate(GO:0010133)
0.3	3.9	GO:0002934	desmosome organization(GO:0002934)
0.3	1.4	GO:0044727	DNA demethylation of male pronucleus(GO:0044727)
0.3	2.8	GO:0070245	positive regulation of thymocyte apoptotic process(GO:0070245)
0.3	1.1	GO:1901301	regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.3	0.8	GO:0014908	myotube differentiation involved in skeletal muscle regeneration(GO:0014908)
0.3	1.8	GO:0015862	uridine transport(GO:0015862)
0.3	1.3	GO:1990743	protein sialylation(GO:1990743)
0.2	2.0	GO:0070447	positive regulation of oligodendrocyte progenitor proliferation(GO:0070447)
0.2	0.7	GO:0097052	L-kynurenine metabolic process(GO:0097052)
0.2	2.2	GO:1900264	regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.2	2.7	GO:0007076	mitotic chromosome condensation(GO:0007076)
0.2	3.1	GO:0043031	negative regulation of macrophage activation(GO:0043031)
0.2	1.7	GO:0070234	positive regulation of T cell apoptotic process(GO:0070234)
0.2	6.9	GO:0035455	response to interferon-alpha(GO:0035455)
0.2	3.0	GO:0032570	response to progesterone(GO:0032570)
0.2	0.7	GO:0046619	optic placode formation involved in camera-type eye formation(GO:0046619)
0.2	0.7	GO:0060392	negative regulation of SMAD protein import into nucleus(GO:0060392)
0.2	6.8	GO:0044364	killing of cells of other organism(GO:0031640) disruption of cells of other organism(GO:0044364)
0.2	1.1	GO:0006420	arginyl-tRNA aminoacylation(GO:0006420)
0.2	0.7	GO:2001160	regulation of histone H3-K79 methylation(GO:2001160)
0.2	6.4	GO:0006474	N-terminal protein amino acid acetylation(GO:0006474)
0.2	2.8	GO:1902231	positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.2	2.5	GO:0002227	innate immune response in mucosa(GO:0002227)
0.2	5.3	GO:0045793	positive regulation of cell size(GO:0045793)
0.2	1.2	GO:0038044	transforming growth factor-beta secretion(GO:0038044)
0.2	3.1	GO:0010839	negative regulation of keratinocyte proliferation(GO:0010839)
0.2	2.0	GO:0070253	somatostatin secretion(GO:0070253)
0.2	5.5	GO:0046457	prostaglandin biosynthetic process(GO:0001516) prostanoid biosynthetic process(GO:0046457)
0.2	30.4	GO:0006958	complement activation, classical pathway(GO:0006958)
0.2	4.3	GO:0007100	mitotic centrosome separation(GO:0007100)
0.2	8.2	GO:0030225	macrophage differentiation(GO:0030225)
0.2	2.3	GO:1990118	sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.2	0.8	GO:0010510	regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.2	0.8	GO:0046606	negative regulation of centrosome duplication(GO:0010826) negative regulation of centrosome cycle(GO:0046606)
0.2	1.5	GO:0043129	surfactant homeostasis(GO:0043129)
0.2	1.3	GO:0030263	apoptotic chromosome condensation(GO:0030263)
0.2	0.6	GO:0002018	renin-angiotensin regulation of aldosterone production(GO:0002018)
0.2	0.6	GO:0036088	proline catabolic process(GO:0006562) D-serine catabolic process(GO:0036088) D-alanine family amino acid metabolic process(GO:0046144) D-alanine metabolic process(GO:0046436) D-alanine catabolic process(GO:0055130)
0.2	0.4	GO:0090362	positive regulation of platelet-derived growth factor production(GO:0090362)
0.2	6.1	GO:0045671	negative regulation of osteoclast differentiation(GO:0045671)
0.2	5.2	GO:0045948	positive regulation of translational initiation(GO:0045948)
0.2	1.8	GO:0045409	negative regulation of interleukin-6 biosynthetic process(GO:0045409)
0.2	3.0	GO:0070995	NADPH oxidation(GO:0070995)
0.2	1.4	GO:0031508	pericentric heterochromatin assembly(GO:0031508)
0.2	0.7	GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent(GO:0002479) peptide stabilization(GO:0050822) peptide antigen stabilization(GO:0050823)
0.2	1.9	GO:0090500	endocardial cushion to mesenchymal transition(GO:0090500)
0.2	3.7	GO:0007252	I-kappaB phosphorylation(GO:0007252)
0.2	1.0	GO:0090158	endoplasmic reticulum membrane organization(GO:0090158)
0.2	1.5	GO:1903142	positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.2	2.2	GO:2000298	regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
0.2	1.1	GO:0015722	canalicular bile acid transport(GO:0015722)
0.2	10.1	GO:0018149	peptide cross-linking(GO:0018149)
0.2	0.8	GO:0006566	threonine metabolic process(GO:0006566)
0.2	1.9	GO:0008635	activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.2	5.6	GO:0000027	ribosomal large subunit assembly(GO:0000027)
0.2	0.6	GO:0035519	protein K29-linked ubiquitination(GO:0035519)
0.2	0.8	GO:0039534	negative regulation of MDA-5 signaling pathway(GO:0039534)
0.2	1.4	GO:2000491	positive regulation of hepatic stellate cell activation(GO:2000491)
0.1	7.2	GO:0035458	cellular response to interferon-beta(GO:0035458)
0.1	2.3	GO:0030259	lipid glycosylation(GO:0030259)
0.1	2.3	GO:0006488	dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.1	3.4	GO:0006907	pinocytosis(GO:0006907)
0.1	1.4	GO:0021506	anterior neuropore closure(GO:0021506) neuropore closure(GO:0021995)
0.1	1.4	GO:0010727	negative regulation of hydrogen peroxide metabolic process(GO:0010727)
0.1	0.8	GO:2000327	regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000325) positive regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000327)
0.1	0.9	GO:0006957	complement activation, alternative pathway(GO:0006957)
0.1	6.5	GO:0071346	cellular response to interferon-gamma(GO:0071346)
0.1	0.4	GO:0045041	protein import into mitochondrial intermembrane space(GO:0045041)
0.1	0.4	GO:0021762	substantia nigra development(GO:0021762)
0.1	4.1	GO:0051482	positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.1	2.7	GO:1900037	regulation of cellular response to hypoxia(GO:1900037)
0.1	0.7	GO:0030043	actin filament fragmentation(GO:0030043)
0.1	0.4	GO:0018171	peptidyl-cysteine oxidation(GO:0018171)
0.1	4.8	GO:0060445	branching involved in salivary gland morphogenesis(GO:0060445)
0.1	1.1	GO:0061091	regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
0.1	1.2	GO:2000051	negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.1	1.5	GO:0000083	regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.1	1.5	GO:0010917	negative regulation of mitochondrial membrane potential(GO:0010917)
0.1	4.3	GO:0051497	negative regulation of stress fiber assembly(GO:0051497)
0.1	2.6	GO:0001967	suckling behavior(GO:0001967)
0.1	1.3	GO:0002826	negative regulation of T-helper 1 type immune response(GO:0002826)
0.1	3.1	GO:0071260	cellular response to mechanical stimulus(GO:0071260)
0.1	2.2	GO:0046597	negative regulation of viral entry into host cell(GO:0046597)
0.1	22.7	GO:0002377	immunoglobulin production(GO:0002377)
0.1	1.0	GO:0070831	basement membrane assembly(GO:0070831)
0.1	2.1	GO:0016188	synaptic vesicle maturation(GO:0016188)
0.1	0.7	GO:0021776	smoothened signaling pathway involved in ventral spinal cord interneuron specification(GO:0021775) smoothened signaling pathway involved in spinal cord motor neuron cell fate specification(GO:0021776)
0.1	1.8	GO:0007175	negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.1	1.2	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
0.1	3.5	GO:0007099	centriole replication(GO:0007099)
0.1	1.5	GO:0048935	peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.1	1.3	GO:0090315	negative regulation of protein targeting to membrane(GO:0090315)
0.1	0.3	GO:0000973	posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.1	1.5	GO:0042640	anagen(GO:0042640)
0.1	0.2	GO:0071639	positive regulation of monocyte chemotactic protein-1 production(GO:0071639)
0.1	1.8	GO:1902236	negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236)
0.1	1.2	GO:0031274	positive regulation of pseudopodium assembly(GO:0031274)
0.1	2.3	GO:0045662	negative regulation of myoblast differentiation(GO:0045662)
0.1	1.7	GO:0070571	negative regulation of neuron projection regeneration(GO:0070571)
0.1	0.7	GO:0014816	skeletal muscle satellite cell differentiation(GO:0014816)
0.1	1.0	GO:0006228	UTP biosynthetic process(GO:0006228)
0.1	1.0	GO:0046007	negative regulation of activated T cell proliferation(GO:0046007)
0.1	6.4	GO:0050868	negative regulation of T cell activation(GO:0050868)
0.1	4.5	GO:0001954	positive regulation of cell-matrix adhesion(GO:0001954)
0.1	0.8	GO:0006968	cellular defense response(GO:0006968)
0.1	0.8	GO:0015074	DNA integration(GO:0015074)
0.1	11.8	GO:0042113	B cell activation(GO:0042113)
0.1	0.5	GO:0031507	heterochromatin assembly(GO:0031507)
0.1	0.5	GO:0051533	positive regulation of NFAT protein import into nucleus(GO:0051533)
0.1	0.3	GO:1904177	regulation of adipose tissue development(GO:1904177)
0.1	0.6	GO:0019530	taurine metabolic process(GO:0019530)
0.1	0.4	GO:0009235	cobalamin metabolic process(GO:0009235)
0.1	3.1	GO:0006879	cellular iron ion homeostasis(GO:0006879)
0.1	0.8	GO:0015816	glycine transport(GO:0015816)
0.1	0.6	GO:0006398	mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.1	2.3	GO:1900026	positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.1	2.9	GO:0007339	binding of sperm to zona pellucida(GO:0007339)
0.1	0.4	GO:0032790	ribosome disassembly(GO:0032790)
0.1	2.2	GO:0006270	DNA replication initiation(GO:0006270)
0.1	0.5	GO:0031017	exocrine pancreas development(GO:0031017)
0.0	0.4	GO:0070268	cornification(GO:0070268)
0.0	0.4	GO:0035437	maintenance of protein localization in endoplasmic reticulum(GO:0035437)
0.0	0.8	GO:0035493	SNARE complex assembly(GO:0035493)
0.0	1.1	GO:0060736	prostate gland growth(GO:0060736)
0.0	0.5	GO:0007021	tubulin complex assembly(GO:0007021)
0.0	1.1	GO:0001522	pseudouridine synthesis(GO:0001522)
0.0	6.7	GO:0007030	Golgi organization(GO:0007030)
0.0	0.1	GO:1901979	regulation of inward rectifier potassium channel activity(GO:1901979)
0.0	0.8	GO:0072673	lamellipodium morphogenesis(GO:0072673)
0.0	0.5	GO:0007220	Notch receptor processing(GO:0007220)
0.0	3.3	GO:0030216	keratinocyte differentiation(GO:0030216)
0.0	1.1	GO:0048745	smooth muscle tissue development(GO:0048745)
0.0	0.3	GO:0035878	nail development(GO:0035878)
0.0	0.4	GO:1900246	positive regulation of RIG-I signaling pathway(GO:1900246)
0.0	6.4	GO:0002244	hematopoietic progenitor cell differentiation(GO:0002244)
0.0	6.5	GO:0006364	rRNA processing(GO:0006364)
0.0	0.9	GO:0030857	negative regulation of epithelial cell differentiation(GO:0030857)
0.0	1.5	GO:1900087	positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.0	0.9	GO:0040015	negative regulation of multicellular organism growth(GO:0040015)
0.0	1.6	GO:0002181	cytoplasmic translation(GO:0002181)
0.0	6.3	GO:0007596	blood coagulation(GO:0007596)
0.0	1.6	GO:0033120	positive regulation of RNA splicing(GO:0033120)
0.0	1.4	GO:0033119	negative regulation of RNA splicing(GO:0033119)
0.0	0.9	GO:0031050	dsRNA fragmentation(GO:0031050) production of miRNAs involved in gene silencing by miRNA(GO:0035196) production of small RNA involved in gene silencing by RNA(GO:0070918)
0.0	1.3	GO:0050688	regulation of defense response to virus(GO:0050688)
0.0	0.8	GO:0044342	type B pancreatic cell proliferation(GO:0044342)
0.0	1.1	GO:0001580	detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0	0.6	GO:0009081	branched-chain amino acid metabolic process(GO:0009081)
0.0	0.7	GO:1904355	positive regulation of telomere capping(GO:1904355)
0.0	0.8	GO:0043984	histone H4-K16 acetylation(GO:0043984)
0.0	0.7	GO:0006817	phosphate ion transport(GO:0006817)
0.0	0.5	GO:0046519	sphingoid metabolic process(GO:0046519)
0.0	1.2	GO:0032729	positive regulation of interferon-gamma production(GO:0032729)
0.0	1.3	GO:0006730	one-carbon metabolic process(GO:0006730)
0.0	0.2	GO:0006348	chromatin silencing at telomere(GO:0006348)
0.0	0.9	GO:0030866	cortical actin cytoskeleton organization(GO:0030866)
0.0	0.8	GO:0006346	methylation-dependent chromatin silencing(GO:0006346)
0.0	3.0	GO:0007050	cell cycle arrest(GO:0007050)
0.0	0.5	GO:0060716	labyrinthine layer blood vessel development(GO:0060716)
0.0	0.7	GO:0015804	neutral amino acid transport(GO:0015804)
0.0	0.2	GO:1900364	negative regulation of mRNA polyadenylation(GO:1900364)
0.0	0.3	GO:0048368	lateral mesoderm development(GO:0048368)
0.0	0.4	GO:0030033	microvillus assembly(GO:0030033)
0.0	0.6	GO:0048240	sperm capacitation(GO:0048240)
0.0	0.3	GO:0045943	positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.0	0.7	GO:0060351	cartilage development involved in endochondral bone morphogenesis(GO:0060351)
0.0	0.3	GO:1900153	regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900151) positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900153)
0.0	1.7	GO:0007338	single fertilization(GO:0007338)
0.0	1.3	GO:0043525	positive regulation of neuron apoptotic process(GO:0043525)
0.0	0.1	GO:0002266	follicular dendritic cell activation(GO:0002266) follicular dendritic cell differentiation(GO:0002268)
0.0	0.8	GO:0042475	odontogenesis of dentin-containing tooth(GO:0042475)
0.0	1.4	GO:0006261	DNA-dependent DNA replication(GO:0006261)
0.0	0.3	GO:0090200	positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.0	0.4	GO:1902230	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)
0.0	1.1	GO:0043473	pigmentation(GO:0043473)
0.0	0.0	GO:0051122	hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.0	0.7	GO:0045727	positive regulation of translation(GO:0045727)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.8	17.0	GO:0005971	ribonucleoside-diphosphate reductase complex(GO:0005971)
1.4	15.4	GO:0042629	mast cell granule(GO:0042629)
1.4	4.1	GO:0097233	lamellar body membrane(GO:0097232) alveolar lamellar body membrane(GO:0097233)
1.0	3.8	GO:0071942	XPC complex(GO:0071942)
0.7	8.5	GO:0097524	sperm plasma membrane(GO:0097524)
0.6	2.8	GO:0030896	checkpoint clamp complex(GO:0030896)
0.5	8.8	GO:0035631	CD40 receptor complex(GO:0035631)
0.5	5.7	GO:0000796	condensin complex(GO:0000796)
0.5	8.2	GO:0000346	transcription export complex(GO:0000346)
0.4	2.4	GO:0032133	chromosome passenger complex(GO:0032133)
0.4	6.7	GO:0031254	uropod(GO:0001931) cell trailing edge(GO:0031254)
0.4	6.2	GO:0017101	aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.4	1.9	GO:0043293	apoptosome(GO:0043293)
0.4	1.8	GO:0000839	Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.4	10.6	GO:0000242	pericentriolar material(GO:0000242)
0.3	1.0	GO:0034751	aryl hydrocarbon receptor complex(GO:0034751)
0.3	1.5	GO:0097209	epidermal lamellar body(GO:0097209)
0.3	4.1	GO:0020005	symbiont-containing vacuole membrane(GO:0020005)
0.3	3.8	GO:0097136	Bcl-2 family protein complex(GO:0097136)
0.3	23.0	GO:0022625	cytosolic large ribosomal subunit(GO:0022625)
0.3	7.1	GO:0031362	anchored component of external side of plasma membrane(GO:0031362)
0.3	2.8	GO:0032541	cortical endoplasmic reticulum(GO:0032541)
0.2	1.2	GO:0034685	integrin alphav-beta6 complex(GO:0034685)
0.2	0.7	GO:0042643	actomyosin, actin portion(GO:0042643)
0.2	9.9	GO:0034364	high-density lipoprotein particle(GO:0034364)
0.2	28.9	GO:0042571	immunoglobulin complex, circulating(GO:0042571)
0.2	7.4	GO:0030057	desmosome(GO:0030057)
0.2	2.0	GO:0070652	HAUS complex(GO:0070652)
0.2	0.7	GO:0055087	Ski complex(GO:0055087)
0.2	2.2	GO:0031390	Ctf18 RFC-like complex(GO:0031390)
0.2	12.0	GO:0001533	cornified envelope(GO:0001533)
0.2	4.3	GO:0031616	spindle pole centrosome(GO:0031616)
0.2	5.2	GO:0031527	filopodium membrane(GO:0031527)
0.2	1.2	GO:0071008	U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.2	1.6	GO:0097422	extrinsic component of endosome membrane(GO:0031313) tubular endosome(GO:0097422)
0.2	2.6	GO:0044233	ER-mitochondrion membrane contact site(GO:0044233)
0.2	2.0	GO:0031232	extrinsic component of external side of plasma membrane(GO:0031232)
0.2	1.3	GO:0097443	sorting endosome(GO:0097443)
0.2	1.3	GO:0072487	MSL complex(GO:0072487)
0.2	75.2	GO:0009897	external side of plasma membrane(GO:0009897)
0.2	3.2	GO:0045180	basal cortex(GO:0045180)
0.2	2.2	GO:0032584	growth cone membrane(GO:0032584)
0.2	0.8	GO:0070820	tertiary granule(GO:0070820)
0.2	2.6	GO:0042555	MCM complex(GO:0042555)
0.1	2.5	GO:0042582	primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.1	1.0	GO:0005784	Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.1	1.7	GO:0031415	NatA complex(GO:0031415)
0.1	1.3	GO:0061574	ASAP complex(GO:0061574)
0.1	0.8	GO:0001674	female germ cell nucleus(GO:0001674)
0.1	4.3	GO:0045120	pronucleus(GO:0045120)
0.1	1.6	GO:0005614	interstitial matrix(GO:0005614)
0.1	1.6	GO:0005736	DNA-directed RNA polymerase I complex(GO:0005736)
0.1	0.5	GO:0031084	BLOC-2 complex(GO:0031084)
0.1	1.4	GO:0000176	nuclear exosome (RNase complex)(GO:0000176)
0.1	5.8	GO:0005719	nuclear euchromatin(GO:0005719)
0.1	3.7	GO:0005721	pericentric heterochromatin(GO:0005721)
0.1	1.0	GO:0000808	origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.1	0.6	GO:0005947	mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.1	1.3	GO:0000138	Golgi trans cisterna(GO:0000138)
0.1	1.2	GO:0034663	endoplasmic reticulum chaperone complex(GO:0034663)
0.1	2.5	GO:0005682	U5 snRNP(GO:0005682)
0.1	6.1	GO:0005834	heterotrimeric G-protein complex(GO:0005834)
0.1	0.3	GO:0000836	ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836)
0.1	0.7	GO:0042825	MHC class I peptide loading complex(GO:0042824) TAP complex(GO:0042825)
0.1	4.7	GO:0015030	Cajal body(GO:0015030)
0.1	0.3	GO:0071148	TEAD-1-YAP complex(GO:0071148)
0.1	4.7	GO:0022627	cytosolic small ribosomal subunit(GO:0022627)
0.1	2.2	GO:0090545	NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.1	0.5	GO:0071556	integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.1	0.8	GO:0030015	CCR4-NOT core complex(GO:0030015)
0.1	0.3	GO:0044614	nuclear pore cytoplasmic filaments(GO:0044614)
0.1	0.5	GO:0032937	SREBP-SCAP-Insig complex(GO:0032937)
0.1	1.0	GO:0005952	cAMP-dependent protein kinase complex(GO:0005952)
0.1	2.8	GO:0005771	multivesicular body(GO:0005771)
0.1	3.8	GO:0045171	intercellular bridge(GO:0045171)
0.1	2.2	GO:0055038	recycling endosome membrane(GO:0055038)
0.1	0.2	GO:1904602	serotonin-activated cation-selective channel complex(GO:1904602)
0.1	1.0	GO:1990023	mitotic spindle midzone(GO:1990023)
0.1	1.5	GO:0000777	condensed chromosome kinetochore(GO:0000777)
0.1	2.4	GO:0031902	late endosome membrane(GO:0031902)
0.0	0.5	GO:0070765	gamma-secretase complex(GO:0070765)
0.0	0.8	GO:0042589	zymogen granule membrane(GO:0042589)
0.0	0.8	GO:0032433	filopodium tip(GO:0032433)
0.0	0.5	GO:0005677	chromatin silencing complex(GO:0005677)
0.0	0.3	GO:0005638	lamin filament(GO:0005638)
0.0	0.8	GO:0046581	intercellular canaliculus(GO:0046581)
0.0	4.8	GO:0017053	transcriptional repressor complex(GO:0017053)
0.0	0.5	GO:0016272	prefoldin complex(GO:0016272)
0.0	3.9	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0	4.9	GO:0016605	PML body(GO:0016605)
0.0	0.2	GO:0035841	new growing cell tip(GO:0035841)
0.0	0.6	GO:0005641	nuclear envelope lumen(GO:0005641)
0.0	0.9	GO:0017146	NMDA selective glutamate receptor complex(GO:0017146)
0.0	0.6	GO:0005847	mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0	0.2	GO:0070876	SOSS complex(GO:0070876)
0.0	0.7	GO:0036057	filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0	5.2	GO:0001669	acrosomal vesicle(GO:0001669)
0.0	12.3	GO:0016607	nuclear speck(GO:0016607)
0.0	0.4	GO:0008385	IkappaB kinase complex(GO:0008385)
0.0	0.9	GO:0032040	small-subunit processome(GO:0032040)
0.0	1.0	GO:0045095	keratin filament(GO:0045095)
0.0	0.4	GO:0035145	exon-exon junction complex(GO:0035145)
0.0	0.2	GO:0044666	MLL3/4 complex(GO:0044666)
0.0	3.5	GO:0032432	actin filament bundle(GO:0032432)
0.0	0.6	GO:0005680	anaphase-promoting complex(GO:0005680)
0.0	2.8	GO:0045111	intermediate filament cytoskeleton(GO:0045111)
0.0	2.6	GO:0030496	midbody(GO:0030496)
0.0	4.1	GO:0009898	cytoplasmic side of plasma membrane(GO:0009898)
0.0	1.7	GO:0005776	autophagosome(GO:0005776)
0.0	0.4	GO:0005605	basal lamina(GO:0005605)
0.0	4.7	GO:0016323	basolateral plasma membrane(GO:0016323)
0.0	1.2	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.0	1.5	GO:0031526	brush border membrane(GO:0031526)
0.0	1.7	GO:0005791	rough endoplasmic reticulum(GO:0005791)
0.0	0.1	GO:0033257	Bcl3/NF-kappaB2 complex(GO:0033257)
0.0	7.9	GO:0005667	transcription factor complex(GO:0005667)
0.0	0.5	GO:0035869	ciliary transition zone(GO:0035869)
0.0	0.3	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.0	0.1	GO:0030914	STAGA complex(GO:0030914)
0.0	18.5	GO:0005615	extracellular space(GO:0005615)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
3.1	9.2	GO:0004982	N-formyl peptide receptor activity(GO:0004982)
3.0	24.0	GO:0035662	Toll-like receptor 4 binding(GO:0035662)
2.8	17.0	GO:0061731	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
2.4	12.0	GO:0042610	CD8 receptor binding(GO:0042610)
1.6	8.1	GO:0019976	interleukin-2 binding(GO:0019976)
1.5	4.6	GO:0035717	chemokine (C-C motif) ligand 7 binding(GO:0035717)
1.5	16.0	GO:0070053	thrombospondin receptor activity(GO:0070053)
1.3	5.2	GO:0004711	ribosomal protein S6 kinase activity(GO:0004711)
1.2	6.2	GO:0035478	chylomicron binding(GO:0035478)
1.2	5.8	GO:0008853	exodeoxyribonuclease III activity(GO:0008853)
1.1	3.4	GO:0050785	advanced glycation end-product receptor activity(GO:0050785)
1.0	8.1	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
1.0	5.0	GO:0034481	chondroitin sulfotransferase activity(GO:0034481)
1.0	11.5	GO:0019992	diacylglycerol binding(GO:0019992)
0.9	2.8	GO:0052642	lysophosphatidic acid phosphatase activity(GO:0052642)
0.9	4.7	GO:0008859	exoribonuclease II activity(GO:0008859)
0.9	4.5	GO:0043546	xanthine dehydrogenase activity(GO:0004854) oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor(GO:0016726) molybdenum ion binding(GO:0030151) molybdopterin cofactor binding(GO:0043546)
0.9	9.7	GO:0019957	C-C chemokine binding(GO:0019957)
0.8	6.8	GO:0019834	phospholipase A2 inhibitor activity(GO:0019834)
0.7	6.6	GO:0055104	ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.7	16.2	GO:0042288	MHC class I protein binding(GO:0042288)
0.7	9.5	GO:0045236	CXCR chemokine receptor binding(GO:0045236)
0.7	2.0	GO:0005026	transforming growth factor beta receptor activity, type II(GO:0005026)
0.7	2.6	GO:0005093	Rab GDP-dissociation inhibitor activity(GO:0005093)
0.6	2.5	GO:0003827	alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.6	9.0	GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.6	5.4	GO:0016936	galactoside binding(GO:0016936)
0.6	5.9	GO:1990189	peptide-serine-N-acetyltransferase activity(GO:1990189)
0.6	15.0	GO:0023026	MHC class II protein complex binding(GO:0023026)
0.6	6.8	GO:0035368	selenocysteine insertion sequence binding(GO:0035368)
0.6	2.8	GO:0019962	interferon receptor activity(GO:0004904) type I interferon receptor activity(GO:0004905) type I interferon binding(GO:0019962)
0.5	8.0	GO:0030274	LIM domain binding(GO:0030274)
0.5	1.5	GO:0034191	apolipoprotein A-I receptor binding(GO:0034191)
0.5	10.1	GO:0001608	G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.5	5.4	GO:0003810	protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.5	1.8	GO:0003976	UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.5	5.4	GO:0004499	N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.4	3.1	GO:0030549	acetylcholine receptor activator activity(GO:0030549)
0.4	1.3	GO:0002113	interleukin-33 binding(GO:0002113)
0.4	2.9	GO:0019770	IgG receptor activity(GO:0019770)
0.4	2.7	GO:0004957	prostaglandin E receptor activity(GO:0004957)
0.4	1.8	GO:0003987	acetate-CoA ligase activity(GO:0003987)
0.4	2.8	GO:0015349	thyroid hormone transmembrane transporter activity(GO:0015349)
0.3	4.9	GO:0015093	ferrous iron transmembrane transporter activity(GO:0015093)
0.3	1.3	GO:0000702	oxidized base lesion DNA N-glycosylase activity(GO:0000702)
0.3	1.0	GO:0036004	GAF domain binding(GO:0036004)
0.3	1.6	GO:0004920	interleukin-10 receptor activity(GO:0004920)
0.3	4.5	GO:0071933	Arp2/3 complex binding(GO:0071933)
0.3	1.3	GO:0015057	thrombin receptor activity(GO:0015057)
0.3	3.1	GO:0004064	arylesterase activity(GO:0004064)
0.3	1.5	GO:0032767	copper-dependent protein binding(GO:0032767)
0.3	1.4	GO:0004060	arylamine N-acetyltransferase activity(GO:0004060)
0.3	2.0	GO:0015091	ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.3	9.6	GO:0005035	tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.3	2.2	GO:0034235	GPI anchor binding(GO:0034235)
0.3	1.7	GO:1990050	phosphatidic acid transporter activity(GO:1990050)
0.3	1.9	GO:0016361	activin receptor activity, type I(GO:0016361)
0.3	13.7	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.3	2.9	GO:1990247	N6-methyladenosine-containing RNA binding(GO:1990247)
0.3	1.5	GO:0070180	large ribosomal subunit rRNA binding(GO:0070180)
0.3	11.4	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.2	0.7	GO:0070540	stearic acid binding(GO:0070540)
0.2	0.7	GO:0047312	L-phenylalanine:pyruvate aminotransferase activity(GO:0047312) glutamine-phenylpyruvate transaminase activity(GO:0047316) L-glutamine:pyruvate aminotransferase activity(GO:0047945)
0.2	1.9	GO:0004865	protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.2	7.4	GO:0030247	pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.2	2.3	GO:0015386	potassium:proton antiporter activity(GO:0015386)
0.2	1.1	GO:0004814	arginine-tRNA ligase activity(GO:0004814)
0.2	6.7	GO:0043395	heparan sulfate proteoglycan binding(GO:0043395)
0.2	4.9	GO:0030296	protein tyrosine kinase activator activity(GO:0030296)
0.2	28.9	GO:0034987	immunoglobulin receptor binding(GO:0034987)
0.2	4.6	GO:0031702	type 1 angiotensin receptor binding(GO:0031702)
0.2	1.3	GO:0003835	beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.2	1.3	GO:0038085	vascular endothelial growth factor binding(GO:0038085)
0.2	0.8	GO:0048495	Roundabout binding(GO:0048495)
0.2	1.3	GO:0016721	superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.2	0.8	GO:0019237	centromeric DNA binding(GO:0019237)
0.2	2.7	GO:1990380	Lys48-specific deubiquitinase activity(GO:1990380)
0.2	7.1	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
0.2	4.4	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.2	1.4	GO:0032795	heterotrimeric G-protein binding(GO:0032795)
0.2	2.2	GO:0003689	DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.2	0.8	GO:0004740	pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.2	2.6	GO:0005041	low-density lipoprotein receptor activity(GO:0005041)
0.2	2.5	GO:0019869	chloride channel inhibitor activity(GO:0019869)
0.2	0.4	GO:0004859	phospholipase inhibitor activity(GO:0004859)
0.2	0.9	GO:0070287	ferritin receptor activity(GO:0070287)
0.2	0.7	GO:0046978	TAP1 binding(GO:0046978) TAP2 binding(GO:0046979)
0.2	2.6	GO:0031957	very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.2	2.0	GO:0046790	virion binding(GO:0046790)
0.2	2.3	GO:0015187	glycine transmembrane transporter activity(GO:0015187)
0.2	1.6	GO:0050733	RS domain binding(GO:0050733)
0.2	1.8	GO:0032052	bile acid binding(GO:0032052)
0.2	0.6	GO:0050220	prostaglandin-D synthase activity(GO:0004667) prostaglandin-E synthase activity(GO:0050220)
0.2	1.2	GO:0072542	protein phosphatase activator activity(GO:0072542)
0.2	1.4	GO:0070579	methylcytosine dioxygenase activity(GO:0070579)
0.2	1.2	GO:0043423	3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.1	2.5	GO:0001206	transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.1	3.1	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.1	1.9	GO:0001054	RNA polymerase I activity(GO:0001054) RNA polymerase II activity(GO:0001055)
0.1	2.3	GO:0051428	peptide hormone receptor binding(GO:0051428)
0.1	0.7	GO:0010484	H3 histone acetyltransferase activity(GO:0010484)
0.1	1.7	GO:0004596	peptide alpha-N-acetyltransferase activity(GO:0004596)
0.1	0.6	GO:0003884	D-amino-acid oxidase activity(GO:0003884)
0.1	2.3	GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.1	3.4	GO:0003746	translation elongation factor activity(GO:0003746)
0.1	0.7	GO:0015319	sodium:inorganic phosphate symporter activity(GO:0015319)
0.1	1.6	GO:0031852	mu-type opioid receptor binding(GO:0031852)
0.1	1.9	GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.1	3.1	GO:0017049	GTP-Rho binding(GO:0017049)
0.1	0.5	GO:0036313	phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.1	4.1	GO:0045295	gamma-catenin binding(GO:0045295)
0.1	1.4	GO:0070181	small ribosomal subunit rRNA binding(GO:0070181)
0.1	1.8	GO:0019865	immunoglobulin binding(GO:0019865)
0.1	0.8	GO:0046848	hydroxyapatite binding(GO:0046848)
0.1	12.7	GO:1990782	protein tyrosine kinase binding(GO:1990782)
0.1	8.2	GO:0001205	transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.1	1.2	GO:0005436	sodium:phosphate symporter activity(GO:0005436)
0.1	2.4	GO:0035174	histone serine kinase activity(GO:0035174)
0.1	0.5	GO:0070097	delta-catenin binding(GO:0070097)
0.1	1.7	GO:0008349	MAP kinase kinase kinase kinase activity(GO:0008349)
0.1	1.8	GO:1904264	ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.1	3.8	GO:0005487	nucleocytoplasmic transporter activity(GO:0005487)
0.1	1.3	GO:0004089	carbonate dehydratase activity(GO:0004089)
0.1	1.1	GO:0030976	thiamine pyrophosphate binding(GO:0030976)
0.1	1.8	GO:0005328	neurotransmitter:sodium symporter activity(GO:0005328)
0.1	5.4	GO:0030544	Hsp70 protein binding(GO:0030544)
0.1	1.4	GO:0032036	myosin heavy chain binding(GO:0032036)
0.1	5.1	GO:0008028	monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.1	5.8	GO:0031491	nucleosome binding(GO:0031491)
0.1	4.5	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1	4.4	GO:0016860	intramolecular oxidoreductase activity(GO:0016860)
0.1	3.7	GO:0001106	RNA polymerase II transcription corepressor activity(GO:0001106)
0.1	11.4	GO:0005089	Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.1	1.0	GO:0043024	ribosomal small subunit binding(GO:0043024)
0.1	2.8	GO:0051059	NF-kappaB binding(GO:0051059)
0.1	9.0	GO:0008013	beta-catenin binding(GO:0008013)
0.1	1.9	GO:0070840	dynein complex binding(GO:0070840)
0.1	1.0	GO:0008603	cAMP-dependent protein kinase regulator activity(GO:0008603)
0.1	1.9	GO:0031005	filamin binding(GO:0031005)
0.1	1.4	GO:0008253	5'-nucleotidase activity(GO:0008253)
0.1	11.7	GO:0003735	structural constituent of ribosome(GO:0003735)
0.1	0.3	GO:0004679	AMP-activated protein kinase activity(GO:0004679)
0.1	1.6	GO:0005520	insulin-like growth factor binding(GO:0005520)
0.1	1.1	GO:0009982	pseudouridine synthase activity(GO:0009982)
0.1	0.3	GO:0015205	purine nucleobase transmembrane transporter activity(GO:0005345) pyrimidine nucleobase transmembrane transporter activity(GO:0005350) nucleobase transmembrane transporter activity(GO:0015205) glycerol channel activity(GO:0015254)
0.1	0.4	GO:0005111	type 2 fibroblast growth factor receptor binding(GO:0005111)
0.1	1.0	GO:0003688	DNA replication origin binding(GO:0003688)
0.1	2.1	GO:1990841	promoter-specific chromatin binding(GO:1990841)
0.1	0.4	GO:0043023	ribosomal large subunit binding(GO:0043023)
0.1	1.3	GO:0070300	phosphatidic acid binding(GO:0070300)
0.1	0.5	GO:0042500	aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0	4.3	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0	0.2	GO:0031705	bombesin receptor binding(GO:0031705)
0.0	0.4	GO:0008172	S-methyltransferase activity(GO:0008172)
0.0	1.2	GO:0051879	Hsp90 protein binding(GO:0051879)
0.0	0.7	GO:0000983	transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.0	8.5	GO:0042393	histone binding(GO:0042393)
0.0	0.4	GO:0097200	cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0	9.0	GO:0004252	serine-type endopeptidase activity(GO:0004252)
0.0	0.4	GO:0031210	phosphatidylcholine binding(GO:0031210)
0.0	1.0	GO:0097602	cullin family protein binding(GO:0097602)
0.0	0.8	GO:0001972	retinoic acid binding(GO:0001972)
0.0	1.7	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0	0.6	GO:0016290	palmitoyl-CoA hydrolase activity(GO:0016290)
0.0	0.3	GO:0008479	queuine tRNA-ribosyltransferase activity(GO:0008479)
0.0	12.3	GO:0005096	GTPase activator activity(GO:0005096)
0.0	0.2	GO:0022850	serotonin-gated cation channel activity(GO:0022850)
0.0	0.4	GO:0017151	DEAD/H-box RNA helicase binding(GO:0017151)
0.0	0.9	GO:0008143	poly(A) binding(GO:0008143)
0.0	2.2	GO:0015485	cholesterol binding(GO:0015485)
0.0	2.3	GO:0003727	single-stranded RNA binding(GO:0003727)
0.0	0.6	GO:0004190	aspartic-type endopeptidase activity(GO:0004190)
0.0	0.2	GO:0034452	dynactin binding(GO:0034452)
0.0	0.7	GO:0004745	retinol dehydrogenase activity(GO:0004745)
0.0	2.0	GO:0019003	GDP binding(GO:0019003)
0.0	0.9	GO:0071949	FAD binding(GO:0071949)
0.0	1.9	GO:0017048	Rho GTPase binding(GO:0017048)
0.0	0.1	GO:0001716	L-amino-acid oxidase activity(GO:0001716)
0.0	0.4	GO:0015035	protein disulfide oxidoreductase activity(GO:0015035)
0.0	0.8	GO:0005484	SNAP receptor activity(GO:0005484)
0.0	0.3	GO:0001134	transcription factor activity, transcription factor recruiting(GO:0001134)
0.0	1.9	GO:0003697	single-stranded DNA binding(GO:0003697)
0.0	5.5	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0	0.1	GO:0015272	ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0	1.4	GO:0004722	protein serine/threonine phosphatase activity(GO:0004722)
0.0	0.0	GO:0005134	interleukin-2 receptor binding(GO:0005134)
0.0	0.5	GO:0019706	protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0	0.4	GO:0042056	chemoattractant activity(GO:0042056)
0.0	0.1	GO:0070679	inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0	0.2	GO:0046527	glucosyltransferase activity(GO:0046527)
0.0	0.6	GO:0061631	ubiquitin conjugating enzyme activity(GO:0061631)
0.0	3.2	GO:0061630	ubiquitin protein ligase activity(GO:0061630)
0.0	0.5	GO:0070888	E-box binding(GO:0070888)
0.0	0.2	GO:1901702	urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0	0.0	GO:0030294	receptor signaling protein tyrosine kinase inhibitor activity(GO:0030294)
0.0	0.5	GO:0016836	hydro-lyase activity(GO:0016836)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.6	9.5	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.5	19.4	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.5	44.8	PID CD8 TCR PATHWAY	TCR signaling in naïve CD8+ T cells
0.3	5.6	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.3	20.1	PID INTEGRIN3 PATHWAY	Beta3 integrin cell surface interactions
0.3	5.7	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.3	5.4	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
0.2	8.1	ST INTERLEUKIN 4 PATHWAY	Interleukin 4 (IL-4) Pathway
0.2	10.3	PID UPA UPAR PATHWAY	Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.2	7.9	PID AMB2 NEUTROPHILS PATHWAY	amb2 Integrin signaling
0.2	24.8	PID E2F PATHWAY	E2F transcription factor network
0.2	1.2	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.2	8.8	PID CD40 PATHWAY	CD40/CD40L signaling
0.2	1.3	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.2	8.1	PID AURORA B PATHWAY	Aurora B signaling
0.2	1.4	PID LYMPH ANGIOGENESIS PATHWAY	VEGFR3 signaling in lymphatic endothelium
0.1	9.0	PID PI3KCI PATHWAY	Class I PI3K signaling events
0.1	3.8	PID IL27 PATHWAY	IL27-mediated signaling events
0.1	5.9	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.1	6.3	PID IL4 2PATHWAY	IL4-mediated signaling events
0.1	4.6	PID SYNDECAN 4 PATHWAY	Syndecan-4-mediated signaling events
0.1	6.5	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.1	1.2	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1	8.3	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.1	1.7	PID EPO PATHWAY	EPO signaling pathway
0.1	9.0	PID TELOMERASE PATHWAY	Regulation of Telomerase
0.1	3.1	ST GA12 PATHWAY	G alpha 12 Pathway
0.1	6.8	PID P53 REGULATION PATHWAY	p53 pathway
0.1	3.5	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1
0.1	7.1	PID RHOA REG PATHWAY	Regulation of RhoA activity
0.1	5.1	PID HES HEY PATHWAY	Notch-mediated HES/HEY network
0.1	1.6	PID TCR PATHWAY	TCR signaling in naïve CD4+ T cells
0.1	1.8	PID HDAC CLASSIII PATHWAY	Signaling events mediated by HDAC Class III
0.1	1.5	PID S1P S1P2 PATHWAY	S1P2 pathway
0.1	1.7	PID FOXO PATHWAY	FoxO family signaling
0.1	3.9	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.1	1.9	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1	1.8	PID ARF6 PATHWAY	Arf6 signaling events
0.1	1.7	PID EPHB FWD PATHWAY	EPHB forward signaling
0.1	1.2	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.1	2.6	SIG CHEMOTAXIS	Genes related to chemotaxis
0.1	2.3	PID CONE PATHWAY	Visual signal transduction: Cones
0.1	3.4	PID CASPASE PATHWAY	Caspase cascade in apoptosis
0.1	3.2	PID MTOR 4PATHWAY	mTOR signaling pathway
0.1	2.0	PID FANCONI PATHWAY	Fanconi anemia pathway
0.1	1.0	PID INTEGRIN A4B1 PATHWAY	Alpha4 beta1 integrin signaling events
0.1	4.7	PID BETA CATENIN NUC PATHWAY	Regulation of nuclear beta catenin signaling and target gene transcription
0.0	9.7	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0	4.6	PID AR PATHWAY	Coregulation of Androgen receptor activity
0.0	2.8	PID CMYB PATHWAY	C-MYB transcription factor network
0.0	2.2	PID HDAC CLASSI PATHWAY	Signaling events mediated by HDAC Class I
0.0	1.5	PID IL12 2PATHWAY	IL12-mediated signaling events
0.0	1.4	PID DELTA NP63 PATHWAY	Validated transcriptional targets of deltaNp63 isoforms
0.0	0.5	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events
0.0	1.6	PID SMAD2 3NUCLEAR PATHWAY	Regulation of nuclear SMAD2/3 signaling
0.0	0.8	PID NETRIN PATHWAY	Netrin-mediated signaling events
0.0	0.7	PID HEDGEHOG GLI PATHWAY	Hedgehog signaling events mediated by Gli proteins
0.0	0.7	ST DIFFERENTIATION PATHWAY IN PC12 CELLS	Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0	0.0	PID IL23 PATHWAY	IL23-mediated signaling events
0.0	0.3	PID HIF1A PATHWAY	Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0	3.7	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0	0.1	ST PHOSPHOINOSITIDE 3 KINASE PATHWAY	PI3K Pathway
0.0	0.3	PID VEGFR1 2 PATHWAY	Signaling events mediated by VEGFR1 and VEGFR2

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.4	12.8	REACTOME BETA DEFENSINS	Genes involved in Beta defensins
1.4	20.3	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.7	17.0	REACTOME G1 S SPECIFIC TRANSCRIPTION	Genes involved in G1/S-Specific Transcription
0.5	15.5	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.5	1.5	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.5	7.7	REACTOME CD28 DEPENDENT VAV1 PATHWAY	Genes involved in CD28 dependent Vav1 pathway
0.5	8.4	REACTOME P2Y RECEPTORS	Genes involved in P2Y receptors
0.5	18.4	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.4	5.4	REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS	Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.4	6.7	REACTOME ACYL CHAIN REMODELLING OF PS	Genes involved in Acyl chain remodelling of PS
0.3	8.7	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.3	8.1	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.3	5.3	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.3	3.2	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts
0.3	2.7	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
0.3	32.9	REACTOME PEPTIDE CHAIN ELONGATION	Genes involved in Peptide chain elongation
0.2	4.5	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
0.2	6.0	REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis
0.2	5.0	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis
0.2	12.4	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.2	2.8	REACTOME TRANSPORT OF ORGANIC ANIONS	Genes involved in Transport of organic anions
0.2	12.4	REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS	Genes involved in Phase 1 - Functionalization of compounds
0.2	5.1	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
0.2	4.8	REACTOME PIP3 ACTIVATES AKT SIGNALING	Genes involved in PIP3 activates AKT signaling
0.2	5.1	REACTOME TRAF6 MEDIATED NFKB ACTIVATION	Genes involved in TRAF6 mediated NF-kB activation
0.2	1.1	REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION	Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.2	2.8	REACTOME REGULATION OF IFNA SIGNALING	Genes involved in Regulation of IFNA signaling
0.2	6.1	REACTOME ADP SIGNALLING THROUGH P2RY12	Genes involved in ADP signalling through P2Y purinoceptor 12
0.2	3.4	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.1	3.3	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1	6.7	REACTOME COSTIMULATION BY THE CD28 FAMILY	Genes involved in Costimulation by the CD28 family
0.1	1.3	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.1	5.3	REACTOME METAL ION SLC TRANSPORTERS	Genes involved in Metal ion SLC transporters
0.1	1.4	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.1	1.3	REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.1	4.2	REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES	Genes involved in Transport of vitamins, nucleosides, and related molecules
0.1	3.5	REACTOME EGFR DOWNREGULATION	Genes involved in EGFR downregulation
0.1	19.3	REACTOME GASTRIN CREB SIGNALLING PATHWAY VIA PKC AND MAPK	Genes involved in Gastrin-CREB signalling pathway via PKC and MAPK
0.1	4.7	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.1	1.0	REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION	Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.1	1.9	REACTOME VIRAL MESSENGER RNA SYNTHESIS	Genes involved in Viral Messenger RNA Synthesis
0.1	8.5	REACTOME G ALPHA1213 SIGNALLING EVENTS	Genes involved in G alpha (12/13) signalling events
0.1	2.8	REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS	Genes involved in Activation of ATR in response to replication stress
0.1	2.5	REACTOME LYSOSOME VESICLE BIOGENESIS	Genes involved in Lysosome Vesicle Biogenesis
0.1	3.1	REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT	Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.1	10.3	REACTOME MRNA SPLICING	Genes involved in mRNA Splicing
0.1	1.4	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1	1.9	REACTOME INTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Intrinsic Pathway for Apoptosis
0.1	4.5	REACTOME NUCLEAR SIGNALING BY ERBB4	Genes involved in Nuclear signaling by ERBB4
0.1	0.9	REACTOME INITIAL TRIGGERING OF COMPLEMENT	Genes involved in Initial triggering of complement
0.1	1.2	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.1	4.1	REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS	Genes involved in Apoptotic cleavage of cellular proteins
0.1	0.8	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1	2.0	REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	Genes involved in Downregulation of TGF-beta receptor signaling
0.1	0.7	REACTOME PROLONGED ERK ACTIVATION EVENTS	Genes involved in Prolonged ERK activation events
0.1	0.8	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0	1.7	REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM	Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.0	1.7	REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN	Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0	0.7	REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS	Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0	6.3	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.0	0.5	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.0	1.6	REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis
0.0	1.0	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0	2.4	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
0.0	0.8	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.0	0.8	REACTOME ACTIVATED POINT MUTANTS OF FGFR2	Genes involved in Activated point mutants of FGFR2
0.0	0.5	REACTOME REGULATION OF BETA CELL DEVELOPMENT	Genes involved in Regulation of beta-cell development
0.0	0.3	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins
0.0	0.8	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.0	0.4	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1	Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.0	0.3	REACTOME HYALURONAN METABOLISM	Genes involved in Hyaluronan metabolism
0.0	0.8	REACTOME RIG I MDA5 MEDIATED INDUCTION OF IFN ALPHA BETA PATHWAYS	Genes involved in RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways
0.0	0.5	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.0	0.3	REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1	Genes involved in Regulation of AMPK activity via LKB1
0.0	0.4	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.0	0.5	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis

Results for Tlx2

Z-value: 1.67

Motif logo

Transcription factors associated with Tlx2

Activity-expression correlation:

Activity profile of Tlx2 motif

Sorted Z-values of Tlx2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Tlx2

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Top targets:

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: