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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Trp53

Z-value: 1.69

Motif logo

Transcription factors associated with Trp53

Gene Symbol Gene ID Gene Info
ENSMUSG00000059552.14 Trp53

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Trp53mm39_v1_chr11_+_69471219_694712480.361.9e-03Click!

Activity profile of Trp53 motif

Sorted Z-values of Trp53 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Trp53

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr17_+_28426752 11.86 ENSMUST00000002327.6
ENSMUST00000233560.2
ENSMUST00000233958.2
ENSMUST00000233170.2
differentially expressed in FDCP 6
chr17_+_35284315 11.75 ENSMUST00000173207.8
lymphocyte antigen 6 complex, locus G6C
chr5_+_36361360 11.66 ENSMUST00000052224.6
prosaposin-like 1
chr2_-_85349362 11.59 ENSMUST00000099923.2
fatty acid desaturase 2B
chr2_-_69036489 11.15 ENSMUST00000127243.8
ENSMUST00000149643.2
ENSMUST00000167875.9
ENSMUST00000005365.15
SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae)
chr1_+_106788873 10.31 ENSMUST00000086701.13
ENSMUST00000188745.3
ENSMUST00000112730.8
serine (or cysteine) peptidase inhibitor, clade B, member 5
chr3_-_132655804 10.11 ENSMUST00000117164.8
ENSMUST00000093971.5
ENSMUST00000042729.16
nephronectin
chr14_-_70412804 9.89 ENSMUST00000143393.2
PDZ and LIM domain 2
chr6_+_41098273 9.73 ENSMUST00000103270.4
T cell receptor beta, variable 13-2
chr3_+_90576285 9.66 ENSMUST00000069927.10
S100 calcium binding protein A8 (calgranulin A)
chr17_+_28426831 9.56 ENSMUST00000233264.2
differentially expressed in FDCP 6
chr8_-_106863521 9.06 ENSMUST00000115979.9
epithelial splicing regulatory protein 2
chr2_-_69036472 8.93 ENSMUST00000112320.8
SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae)
chrX_-_72478938 8.37 ENSMUST00000033738.8
three prime repair exonuclease 2
chr10_-_78554104 8.26 ENSMUST00000005488.9
caspase 14
chr9_-_76474374 8.02 ENSMUST00000183437.8
family with sequence similarity 83, member B
chr3_-_144804784 8.01 ENSMUST00000040465.11
ENSMUST00000198993.2
chloride channel accessory 2
chr8_-_22675773 7.78 ENSMUST00000046916.9
cytoskeleton associated protein 2
chr17_-_34109513 7.76 ENSMUST00000173386.2
ENSMUST00000114361.9
ENSMUST00000173492.9
kinesin family member C1
chr19_+_41017714 7.73 ENSMUST00000051806.12
ENSMUST00000112200.3
deoxynucleotidyltransferase, terminal
chr11_+_81948649 7.70 ENSMUST00000000342.3
chemokine (C-C motif) ligand 11
chr5_-_30278552 7.36 ENSMUST00000198095.2
ENSMUST00000196872.2
ENSMUST00000026846.11
thymidylate synthase
chr14_-_56181993 7.02 ENSMUST00000022834.7
ENSMUST00000226280.2
chymase 1, mast cell
chr7_-_24245419 6.88 ENSMUST00000011776.8
phospholipase A2 inhibitor and LY6/PLAUR domain containing
chr6_-_136918495 6.62 ENSMUST00000111892.8
Rho, GDP dissociation inhibitor (GDI) beta
chr6_-_124698805 6.52 ENSMUST00000173315.8
protein tyrosine phosphatase, non-receptor type 6
chr6_-_136918885 6.51 ENSMUST00000111891.4
Rho, GDP dissociation inhibitor (GDI) beta
chr19_-_57185808 6.47 ENSMUST00000111546.8
actin-binding LIM protein 1
chr4_-_111755892 6.43 ENSMUST00000102720.8
solute carrier family 5 (sodium/glucose cotransporter), member 9
chr4_-_135300934 6.27 ENSMUST00000105855.2
grainyhead like transcription factor 3
chr14_+_73475335 6.25 ENSMUST00000044405.8
lysophosphatidic acid receptor 6
chr2_-_122144125 6.15 ENSMUST00000147788.8
ENSMUST00000154412.2
ENSMUST00000110537.8
ENSMUST00000148417.8
dual oxidase maturation factor 1
chr15_+_79784365 6.14 ENSMUST00000230135.2
apolipoprotein B mRNA editing enzyme, catalytic polypeptide 3
chr1_+_172327569 5.94 ENSMUST00000111230.8
transgelin 2
chr2_-_132787790 5.93 ENSMUST00000038280.5
fermitin family member 1
chr16_+_38279289 5.93 ENSMUST00000099816.3
ENSMUST00000232409.2
CD80 antigen
chr9_-_100368841 5.88 ENSMUST00000098458.4
interleukin 20 receptor beta
chr11_-_3477916 5.61 ENSMUST00000020718.10
smoothelin
chr6_-_136918844 5.60 ENSMUST00000204934.2
Rho, GDP dissociation inhibitor (GDI) beta
chr7_+_140659038 5.56 ENSMUST00000159375.8
plakophilin 3
chr17_+_47747657 5.46 ENSMUST00000150819.3
expressed sequence AI661453
chr14_+_55998847 5.40 ENSMUST00000044554.5
leukotriene B4 receptor 2
chr2_-_163239865 5.36 ENSMUST00000017961.11
ENSMUST00000109425.3
junctophilin 2
chr3_+_59832635 5.31 ENSMUST00000049476.3
AADACL2 family member 1
chr5_+_144127102 5.27 ENSMUST00000060747.8
basic helix-loop-helix family, member a15
chr7_-_24459736 5.25 ENSMUST00000063956.7
CD177 antigen
chr6_-_136918671 5.18 ENSMUST00000032344.12
Rho, GDP dissociation inhibitor (GDI) beta
chr3_-_92481033 5.00 ENSMUST00000053107.6
involucrin
chr14_-_59602882 4.90 ENSMUST00000160425.8
ENSMUST00000095157.11
PHD finger protein 11D
chr17_+_47747540 4.85 ENSMUST00000037701.13
expressed sequence AI661453
chr15_-_102154874 4.83 ENSMUST00000063339.14
retinoic acid receptor, gamma
chr13_-_74956640 4.79 ENSMUST00000231578.2
calpastatin
chr2_-_17735847 4.77 ENSMUST00000028080.12
nebulette
chr6_-_128868068 4.61 ENSMUST00000178918.2
ENSMUST00000160290.8
cDNA sequence BC035044
chr13_+_24560052 4.60 ENSMUST00000110391.4
cytidine monophospho-N-acetylneuraminic acid hydroxylase
chr17_+_87590308 4.60 ENSMUST00000041110.12
ENSMUST00000125875.8
tetratricopeptide repeat domain 7
chr8_-_89362745 4.52 ENSMUST00000034087.9
sorting nexin 20
chr9_+_66853343 4.51 ENSMUST00000040917.14
ENSMUST00000127896.8
ribosomal protein S27-like
chr3_+_59914164 4.48 ENSMUST00000169794.2
arylacetamide deacetylase like 2
chr17_-_35285146 4.48 ENSMUST00000174190.2
ENSMUST00000097337.8
megakaryocyte and platelet inhibitory receptor G6b
chr12_-_78953703 4.40 ENSMUST00000021544.8
pleckstrin 2
chr7_+_75105282 4.40 ENSMUST00000207750.2
ENSMUST00000166315.7
A kinase (PRKA) anchor protein 13
chr18_+_66591604 4.39 ENSMUST00000025399.9
ENSMUST00000237161.2
ENSMUST00000236933.2
phorbol-12-myristate-13-acetate-induced protein 1
chr3_-_92528480 4.39 ENSMUST00000170676.3
late cornified envelope 6A
chr11_-_102815910 4.28 ENSMUST00000021311.10
kinesin family member 18B
chr18_-_35781422 4.24 ENSMUST00000237462.2
marginal zone B and B1 cell-specific protein 1
chr8_-_94006345 4.19 ENSMUST00000034178.9
carboxylesterase 1F
chr2_+_72115981 4.17 ENSMUST00000090824.12
ENSMUST00000135469.8
mitogen-activated protein kinase kinase kinase 20
chr7_+_24584197 4.11 ENSMUST00000156372.8
ENSMUST00000124035.2
ribosomal protein S19
chr4_+_114914880 4.09 ENSMUST00000161601.8
T cell acute lymphocytic leukemia 1
chr4_+_111830119 4.09 ENSMUST00000106568.8
ENSMUST00000055014.11
ENSMUST00000163281.2
selection and upkeep of intraepithelial T cells 7
chr1_+_133278248 4.08 ENSMUST00000094556.3
renin 1 structural
chr4_-_113144152 4.07 ENSMUST00000138966.9
selection and upkeep of intraepithelial T cells 6
chr6_+_67586695 4.03 ENSMUST00000103303.3
immunoglobulin kappa variable 1-135
chr4_+_155874896 4.03 ENSMUST00000165000.8
ankyrin repeat domain 65
chr13_+_94954202 3.98 ENSMUST00000220825.2
tubulin cofactor A
chr6_+_128991064 3.93 ENSMUST00000204981.2
C-type lectin domain family 2, member f
chr1_+_88030951 3.85 ENSMUST00000113135.6
ENSMUST00000113138.8
UDP glucuronosyltransferase 1 family, polypeptide A7C
UDP glucuronosyltransferase 1 family, polypeptide A6B
chr1_-_173810310 3.80 ENSMUST00000000266.9
interferon activated gene 202B
chr3_+_116653113 3.80 ENSMUST00000040260.11
ferric-chelate reductase 1
chr5_-_139805661 3.67 ENSMUST00000147328.2
transmembrane protein 184a
chr10_+_78410803 3.66 ENSMUST00000218763.2
ENSMUST00000220430.2
ENSMUST00000218885.2
ENSMUST00000218215.2
ENSMUST00000218271.2
ilvB (bacterial acetolactate synthase)-like
chr1_-_73967664 3.65 ENSMUST00000187691.7
tensin 1
chr3_-_75864195 3.59 ENSMUST00000038563.14
ENSMUST00000167078.8
ENSMUST00000117242.8
golgi integral membrane protein 4
chr1_+_171386752 3.59 ENSMUST00000004829.13
CD244 molecule A
chr15_+_85744147 3.52 ENSMUST00000231074.2
G two S phase expressed protein 1
chr7_+_24584076 3.45 ENSMUST00000153451.9
ENSMUST00000108429.8
ribosomal protein S19
chr10_+_110581293 3.44 ENSMUST00000174857.8
ENSMUST00000073781.12
ENSMUST00000173471.8
ENSMUST00000173634.2
E2F transcription factor 7
chr1_+_40364752 3.42 ENSMUST00000193388.2
interleukin 1 receptor-like 2
chr6_+_68414401 3.38 ENSMUST00000103324.3
immunoglobulin kappa chain variable 15-103
chr4_-_155141241 3.34 ENSMUST00000131173.3
phospholipase C, eta 2
chr9_+_61280501 3.34 ENSMUST00000162583.8
ENSMUST00000161993.8
ENSMUST00000160882.8
ENSMUST00000160724.8
ENSMUST00000162973.8
ENSMUST00000159050.8
transducin-like enhancer of split 3
chr15_+_85743887 3.25 ENSMUST00000170629.3
G two S phase expressed protein 1
chr1_+_60948149 3.23 ENSMUST00000027164.9
cytotoxic T-lymphocyte-associated protein 4
chr19_-_5399368 3.08 ENSMUST00000238111.2
cystatin E/M
chr7_-_28661751 3.03 ENSMUST00000068045.14
ENSMUST00000217157.2
actinin alpha 4
chr13_-_74956924 3.00 ENSMUST00000223206.2
calpastatin
chr6_-_116437985 2.94 ENSMUST00000164547.8
ENSMUST00000170186.2
arachidonate 5-lipoxygenase
chr15_+_79784543 2.93 ENSMUST00000230741.2
apolipoprotein B mRNA editing enzyme, catalytic polypeptide 3
chr9_+_45313913 2.92 ENSMUST00000214257.2
FXYD domain-containing ion transport regulator 2
chr12_-_70278188 2.82 ENSMUST00000161083.2
liver glycogen phosphorylase
chr7_+_24583994 2.82 ENSMUST00000108428.8
ribosomal protein S19
chr14_-_59602859 2.80 ENSMUST00000161031.2
PHD finger protein 11D
chr17_+_36132567 2.80 ENSMUST00000003635.7
immediate early response 3
chr11_-_115968373 2.80 ENSMUST00000174822.8
unc-13 homolog D
chr6_-_116438116 2.77 ENSMUST00000026795.13
arachidonate 5-lipoxygenase
chr7_-_141023199 2.77 ENSMUST00000106005.9
p53 induced death domain protein 1
chr17_+_27136065 2.76 ENSMUST00000078961.6
kinesin family member C5B
chr9_-_114811807 2.75 ENSMUST00000053150.8
ribosomal protein S27, retrogene
chr10_+_75399920 2.74 ENSMUST00000141062.8
ENSMUST00000152657.8
gamma-glutamyltransferase 1
chr1_+_51328265 2.72 ENSMUST00000051572.8
caveolae associated 2
chr14_+_74973081 2.68 ENSMUST00000177283.8
esterase D/formylglutathione hydrolase
chr4_+_114914607 2.52 ENSMUST00000136946.8
T cell acute lymphocytic leukemia 1
chr12_-_55539372 2.45 ENSMUST00000021413.9
nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha
chr13_-_98951890 2.43 ENSMUST00000040340.16
ENSMUST00000179563.8
ENSMUST00000109403.2
FCH domain only 2
chr1_-_131204422 2.39 ENSMUST00000159195.2
inhibitor of kappaB kinase epsilon
chr17_-_35077089 2.38 ENSMUST00000153400.8
complement factor B
chr11_+_73831074 2.38 ENSMUST00000092917.4
olfactory receptor 23
chrX_+_73298388 2.38 ENSMUST00000119197.8
ENSMUST00000088313.5
emerin
chr5_-_138270995 2.31 ENSMUST00000161665.2
ENSMUST00000100530.8
ENSMUST00000161279.8
ENSMUST00000161647.8
galactose-3-O-sulfotransferase 4
chr9_+_121946321 2.30 ENSMUST00000119215.9
ENSMUST00000146832.8
ENSMUST00000118886.9
ENSMUST00000120173.9
ENSMUST00000139181.2
SNF related kinase
chr14_+_53797089 2.30 ENSMUST00000200101.2
ENSMUST00000103653.3
T cell receptor alpha variable 15-1-DV6-1
chr5_+_92540444 2.25 ENSMUST00000126281.8
ADP-ribosyltransferase 3
chr19_+_36325683 2.23 ENSMUST00000225920.2
polycomb group ring finger 5
chr11_+_17161912 2.22 ENSMUST00000046955.7
WD repeat domain 92
chr10_-_81186025 2.19 ENSMUST00000122993.8
high mobility group 20B
chr1_-_65225617 2.13 ENSMUST00000186222.7
ENSMUST00000169032.8
ENSMUST00000191459.2
ENSMUST00000188876.7
isocitrate dehydrogenase 1 (NADP+), soluble
chr7_-_28661648 2.12 ENSMUST00000127210.8
actinin alpha 4
chr2_-_164699462 2.12 ENSMUST00000109316.8
ENSMUST00000156255.8
ENSMUST00000128110.2
ENSMUST00000109317.10
ENSMUST00000059954.14
phospholipid transfer protein
chr10_-_81186137 2.11 ENSMUST00000167481.8
high mobility group 20B
chr17_+_32725420 2.09 ENSMUST00000235238.2
ENSMUST00000165999.2
cytochrome P450, family 4, subfamily f, polypeptide 17
chr2_-_155434487 2.07 ENSMUST00000155347.2
ENSMUST00000130881.8
ENSMUST00000079691.13
glutathione synthetase
chr9_+_107957621 2.03 ENSMUST00000035211.14
macrophage stimulating 1 (hepatocyte growth factor-like)
chr6_-_131224305 1.99 ENSMUST00000032306.15
ENSMUST00000088867.7
killer cell lectin-like receptor, subfamily A, member 2
chr9_+_72892850 1.99 ENSMUST00000150826.9
ENSMUST00000085350.11
ENSMUST00000140675.8
cell cycle progression 1
chr5_-_116560916 1.99 ENSMUST00000036991.5
heat shock protein 8
chr5_-_66238313 1.98 ENSMUST00000202700.4
ENSMUST00000094757.9
ENSMUST00000113724.6
RNA binding motif protein 47
chr4_+_116414855 1.93 ENSMUST00000030460.15
GC-rich promoter binding protein 1-like 1
chr11_+_55360502 1.85 ENSMUST00000018727.4
GTPase activating protein (SH3 domain) binding protein 1
chr12_+_59142439 1.83 ENSMUST00000219140.3
MIA SH3 domain ER export factor 2
chr11_+_118367651 1.80 ENSMUST00000135383.9
endo-beta-N-acetylglucosaminidase
chr5_-_38659449 1.73 ENSMUST00000005238.13
solute carrier family 2 (facilitated glucose transporter), member 9
chr8_+_70735477 1.73 ENSMUST00000087467.12
ENSMUST00000140212.8
ENSMUST00000110124.9
homer scaffolding protein 3
chr2_+_152360167 1.71 ENSMUST00000121912.2
defensin beta 28
chr11_+_73244561 1.66 ENSMUST00000108465.4
olfactory receptor 20
chr8_-_93806593 1.64 ENSMUST00000109582.3
carboxylesterase 1B
chr11_-_40646090 1.63 ENSMUST00000020576.8
cyclin G1
chr14_-_73563212 1.63 ENSMUST00000022701.7
RB transcriptional corepressor 1
chr7_+_89780785 1.63 ENSMUST00000208684.2
phosphatidylinositol binding clathrin assembly protein
chr9_+_107957640 1.62 ENSMUST00000162886.2
macrophage stimulating 1 (hepatocyte growth factor-like)
chr12_+_59176506 1.62 ENSMUST00000175912.8
ENSMUST00000176892.8
MIA SH3 domain ER export factor 2
chr8_+_84748073 1.60 ENSMUST00000055077.7
paralemmin 3
chr9_-_110886576 1.58 ENSMUST00000199839.5
chemokine (C-C motif) receptor-like 2
chrX_+_73298342 1.56 ENSMUST00000096424.11
emerin
chr5_+_52521133 1.56 ENSMUST00000101208.6
superoxide dismutase 3, extracellular
chr15_-_102259158 1.56 ENSMUST00000231061.2
ENSMUST00000041208.9
achalasia, adrenocortical insufficiency, alacrimia
chr7_+_141047416 1.53 ENSMUST00000209988.2
CD151 antigen
chr8_-_69541852 1.53 ENSMUST00000037478.13
ENSMUST00000148856.2
solute carrier family 18 (vesicular monoamine), member 1
chr12_-_114330574 1.52 ENSMUST00000103485.3
immunoglobulin heavy variable V12-3
chr1_+_78794475 1.49 ENSMUST00000057262.8
ENSMUST00000187432.2
potassium voltage-gated channel, Isk-related subfamily, gene 4
chr9_+_32305259 1.48 ENSMUST00000172015.3
potassium inwardly-rectifying channel, subfamily J, member 1
chr9_+_5298669 1.46 ENSMUST00000238505.2
caspase 1
chr17_-_35081129 1.45 ENSMUST00000154526.8
complement factor B
chr6_-_29212295 1.44 ENSMUST00000078155.12
inosine monophosphate dehydrogenase 1
chrX_+_73298285 1.41 ENSMUST00000002029.13
emerin
chr12_-_113236868 1.41 ENSMUST00000223335.2
ENSMUST00000137336.3
Immunoglobulin heavy constant epsilon
chr6_+_68547717 1.39 ENSMUST00000196839.5
ENSMUST00000103327.3
immunoglobulin kappa variable 12-98
chr8_-_65471175 1.39 ENSMUST00000078409.5
ENSMUST00000048565.9
tripartite motif-containing 61
tripartite motif-containing 60
chr4_+_155875629 1.38 ENSMUST00000105593.2
ankyrin repeat domain 65
chr7_-_3828640 1.37 ENSMUST00000189095.7
ENSMUST00000094911.5
ENSMUST00000153846.8
ENSMUST00000108619.8
ENSMUST00000108620.8
predicted gene 15448
chr3_+_20043315 1.35 ENSMUST00000173779.2
ceruloplasmin
chr12_+_59176543 1.33 ENSMUST00000069430.15
ENSMUST00000177370.8
MIA SH3 domain ER export factor 2
chr17_+_8463886 1.31 ENSMUST00000231545.2
chemokine (C-C motif) receptor 6
chr1_-_131441962 1.30 ENSMUST00000185445.3
SLIT-ROBO Rho GTPase activating protein 2
chrX_-_100777806 1.26 ENSMUST00000056614.7
chemokine (C-X-C motif) receptor 3
chr16_+_20536415 1.21 ENSMUST00000021405.8
polymerase (RNA) II (DNA directed) polypeptide H
chr1_-_65225572 1.20 ENSMUST00000188109.7
isocitrate dehydrogenase 1 (NADP+), soluble
chr4_-_135112956 1.19 ENSMUST00000105857.8
ENSMUST00000105858.8
ENSMUST00000064481.15
ENSMUST00000123632.2
noncompact myelin associated protein
chr9_+_72892693 1.19 ENSMUST00000037977.15
cell cycle progression 1
chr9_+_107454114 1.19 ENSMUST00000112387.9
ENSMUST00000123005.8
ENSMUST00000010195.14
ENSMUST00000144392.2
hyaluronoglucosaminidase 1
chr14_+_53505374 1.18 ENSMUST00000199112.2
T cell receptor alpha variable 15N-2
chr18_+_80296508 1.18 ENSMUST00000157056.8
solute carrier family 66 member 2
chr5_-_38637474 1.17 ENSMUST00000143758.8
ENSMUST00000156272.8
solute carrier family 2 (facilitated glucose transporter), member 9
chr19_-_47126719 1.16 ENSMUST00000140512.8
ENSMUST00000035822.2
calcium homeostasis modulator family member 2
chr2_+_163662752 1.16 ENSMUST00000029188.8
cellular communication network factor 5
chr11_+_66802807 1.14 ENSMUST00000123434.3
phosphoinositide-interacting regulator of transient receptor potential channels
chr7_+_16043502 1.04 ENSMUST00000002152.13
BCL2 binding component 3
chr9_-_75448979 1.02 ENSMUST00000214171.2
tropomodulin 3
chr1_+_174218612 1.02 ENSMUST00000075329.3
olfactory receptor 248
chr3_+_29136172 1.01 ENSMUST00000124809.8
EGF-like and EMI domain containing 1
chr8_+_10027707 1.01 ENSMUST00000139793.8
ENSMUST00000048216.6
abhydrolase domain containing 13
chr9_-_72892617 1.00 ENSMUST00000124565.3
cell cycle progression 1, opposite strand
chr9_+_72892786 0.97 ENSMUST00000156879.8
cell cycle progression 1
chr14_+_53411782 0.97 ENSMUST00000197433.5
ENSMUST00000103590.4
T cell receptor alpha variable 15N-1
chr16_+_20536545 0.97 ENSMUST00000231656.2
polymerase (RNA) II (DNA directed) polypeptide H
chr14_+_75879689 0.96 ENSMUST00000238633.2
ENSMUST00000022579.2
glutamate rich 6B
chr14_-_49303826 0.95 ENSMUST00000161504.8
exocyst complex component 5
chr18_+_80296488 0.93 ENSMUST00000131780.8
solute carrier family 66 member 2
chr11_-_106192627 0.93 ENSMUST00000103071.4
growth hormone
chr5_-_38659422 0.90 ENSMUST00000147664.8
solute carrier family 2 (facilitated glucose transporter), member 9

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.7 23.9 GO:1901164 negative regulation of trophoblast cell migration(GO:1901164)
2.6 10.4 GO:0060265 positive regulation of respiratory burst involved in inflammatory response(GO:0060265)
2.4 9.7 GO:0070488 neutrophil aggregation(GO:0070488)
2.2 6.6 GO:0060217 hemangioblast cell differentiation(GO:0060217)
2.0 10.1 GO:2000721 pilomotor reflex(GO:0097195) positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000721)
2.0 5.9 GO:0048817 negative regulation of hair follicle maturation(GO:0048817)
2.0 5.9 GO:0001807 regulation of type IV hypersensitivity(GO:0001807)
1.9 7.8 GO:0072385 minus-end-directed organelle transport along microtubule(GO:0072385)
1.8 7.0 GO:0042222 interleukin-1 biosynthetic process(GO:0042222)
1.5 7.4 GO:0046073 dTMP biosynthetic process(GO:0006231) dTMP metabolic process(GO:0046073)
1.4 4.2 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
1.3 5.1 GO:1902396 protein localization to bicellular tight junction(GO:1902396)
1.3 3.9 GO:0006711 estrogen catabolic process(GO:0006711)
1.3 5.1 GO:0071930 negative regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071930)
1.3 11.3 GO:0060763 mammary duct terminal end bud growth(GO:0060763)
1.1 4.6 GO:0046381 CMP-N-acetylneuraminate metabolic process(GO:0046381)
1.0 8.3 GO:0070268 cornification(GO:0070268)
1.0 6.1 GO:2000609 regulation of thyroid hormone generation(GO:2000609)
1.0 4.8 GO:0003430 growth plate cartilage chondrocyte growth(GO:0003430)
1.0 5.7 GO:0002540 leukotriene production involved in inflammatory response(GO:0002540)
0.9 5.6 GO:0002159 desmosome assembly(GO:0002159)
0.9 2.7 GO:0046294 formaldehyde catabolic process(GO:0046294)
0.8 4.2 GO:0002378 immunoglobulin biosynthetic process(GO:0002378) negative regulation of glucose import in response to insulin stimulus(GO:2001274)
0.8 3.3 GO:0006097 glyoxylate cycle(GO:0006097)
0.8 6.5 GO:0033277 abortive mitotic cell cycle(GO:0033277)
0.8 4.0 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.7 2.8 GO:0006015 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.7 4.1 GO:0002018 renin-angiotensin regulation of aldosterone production(GO:0002018)
0.7 5.4 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.6 4.5 GO:1900740 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.6 3.7 GO:0018992 germ-line sex determination(GO:0018992)
0.6 2.8 GO:0002432 granuloma formation(GO:0002432)
0.6 4.4 GO:0071883 activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.5 3.2 GO:0045590 negative regulation of regulatory T cell differentiation(GO:0045590)
0.5 2.1 GO:0042360 vitamin E metabolic process(GO:0042360)
0.5 4.2 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.5 6.4 GO:1904659 glucose transmembrane transport(GO:1904659)
0.4 1.3 GO:1904156 DN2 thymocyte differentiation(GO:1904155) DN3 thymocyte differentiation(GO:1904156)
0.4 9.1 GO:0010528 regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529)
0.4 11.7 GO:0060742 epithelial cell differentiation involved in prostate gland development(GO:0060742)
0.4 7.8 GO:2000675 egg activation(GO:0007343) negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.4 2.4 GO:0070427 nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.4 1.2 GO:1900104 hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.4 6.3 GO:0090179 planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.4 1.5 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.4 5.4 GO:0051546 keratinocyte migration(GO:0051546)
0.4 10.3 GO:0060512 prostate gland morphogenesis(GO:0060512)
0.3 2.7 GO:1901748 peptide modification(GO:0031179) leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.3 2.8 GO:1901029 negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
0.3 5.4 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.3 5.3 GO:0006851 mitochondrial calcium ion transport(GO:0006851)
0.3 1.6 GO:1902962 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.3 5.9 GO:0046641 positive regulation of alpha-beta T cell proliferation(GO:0046641)
0.3 0.8 GO:0035425 autocrine signaling(GO:0035425)
0.2 1.2 GO:0038032 termination of G-protein coupled receptor signaling pathway(GO:0038032)
0.2 9.1 GO:0060445 epithelial tube branching involved in lung morphogenesis(GO:0060441) branching involved in salivary gland morphogenesis(GO:0060445)
0.2 3.8 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.2 1.5 GO:0015842 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842)
0.2 4.3 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.2 0.6 GO:1904211 membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211)
0.2 7.5 GO:0033198 response to ATP(GO:0033198)
0.2 1.4 GO:0006177 GMP biosynthetic process(GO:0006177)
0.2 0.8 GO:0000105 histidine biosynthetic process(GO:0000105) 10-formyltetrahydrofolate biosynthetic process(GO:0009257)
0.2 1.2 GO:0032290 peripheral nervous system myelin formation(GO:0032290)
0.2 1.5 GO:0070294 renal sodium ion transport(GO:0003096) renal sodium ion absorption(GO:0070294)
0.2 3.3 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977)
0.2 6.3 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.2 4.5 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.2 0.7 GO:1902044 regulation of Fas signaling pathway(GO:1902044) negative regulation of Fas signaling pathway(GO:1902045)
0.2 1.6 GO:0008063 Toll signaling pathway(GO:0008063)
0.2 2.0 GO:0016554 cytidine to uridine editing(GO:0016554)
0.1 1.3 GO:0021815 cell motility involved in cerebral cortex radial glia guided migration(GO:0021814) modulation of microtubule cytoskeleton involved in cerebral cortex radial glia guided migration(GO:0021815)
0.1 11.0 GO:0007019 microtubule depolymerization(GO:0007019)
0.1 18.8 GO:0007052 mitotic spindle organization(GO:0007052)
0.1 2.7 GO:0046415 urate metabolic process(GO:0046415)
0.1 1.8 GO:0006517 protein deglycosylation(GO:0006517)
0.1 0.7 GO:0016266 O-glycan processing(GO:0016266)
0.1 0.3 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.1 1.3 GO:1900118 negative regulation of execution phase of apoptosis(GO:1900118)
0.1 6.2 GO:0035456 response to interferon-beta(GO:0035456)
0.1 4.2 GO:0000186 activation of MAPKK activity(GO:0000186)
0.1 4.8 GO:0070328 acylglycerol homeostasis(GO:0055090) triglyceride homeostasis(GO:0070328)
0.1 0.2 GO:0046491 L-methylmalonyl-CoA metabolic process(GO:0046491)
0.1 1.0 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.1 5.9 GO:0006879 cellular iron ion homeostasis(GO:0006879)
0.1 1.7 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.1 1.6 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.1 0.7 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.1 3.7 GO:0010761 fibroblast migration(GO:0010761)
0.1 2.1 GO:0046686 response to cadmium ion(GO:0046686)
0.1 6.5 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.9 GO:0090031 positive regulation of steroid hormone biosynthetic process(GO:0090031)
0.0 0.2 GO:0014045 establishment of endothelial blood-brain barrier(GO:0014045)
0.0 0.9 GO:0001675 acrosome assembly(GO:0001675)
0.0 0.9 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.0 8.6 GO:0002377 immunoglobulin production(GO:0002377)
0.0 4.4 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.0 3.4 GO:0045582 positive regulation of T cell differentiation(GO:0045582)
0.0 0.2 GO:0034224 cellular response to zinc ion starvation(GO:0034224)
0.0 0.7 GO:0034389 lipid particle organization(GO:0034389)
0.0 0.4 GO:0071073 positive regulation of phospholipid biosynthetic process(GO:0071073)
0.0 1.1 GO:0048266 behavioral response to pain(GO:0048266)
0.0 0.4 GO:0034501 protein localization to kinetochore(GO:0034501)
0.0 5.4 GO:0010324 membrane invagination(GO:0010324)
0.0 0.4 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.0 1.6 GO:0006801 superoxide metabolic process(GO:0006801)
0.0 0.1 GO:0042636 negative regulation of hair cycle(GO:0042636)
0.0 0.2 GO:0006183 GTP biosynthetic process(GO:0006183)
0.0 0.2 GO:0035455 response to interferon-alpha(GO:0035455)
0.0 2.7 GO:0006821 chloride transport(GO:0006821)
0.0 1.9 GO:0090090 negative regulation of canonical Wnt signaling pathway(GO:0090090)
0.0 2.8 GO:0046488 phosphatidylinositol metabolic process(GO:0046488)
0.0 0.0 GO:0060156 positive regulation of glomerular filtration(GO:0003104) vascular transport(GO:0010232) milk ejection(GO:0060156)
0.0 5.4 GO:0019221 cytokine-mediated signaling pathway(GO:0019221)
0.0 4.7 GO:0050907 detection of chemical stimulus involved in sensory perception(GO:0050907)
0.0 0.9 GO:0006893 Golgi to plasma membrane transport(GO:0006893)
0.0 0.5 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.0 0.2 GO:0097062 dendritic spine maintenance(GO:0097062)
0.0 0.6 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 1.5 GO:0042098 T cell proliferation(GO:0042098)
0.0 1.3 GO:0007173 epidermal growth factor receptor signaling pathway(GO:0007173)
0.0 0.9 GO:0002687 positive regulation of leukocyte migration(GO:0002687)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
3.3 20.1 GO:0031262 Ndc80 complex(GO:0031262)
2.2 6.6 GO:0033193 Lsd1/2 complex(GO:0033193)
1.1 10.1 GO:0030485 smooth muscle contractile fiber(GO:0030485)
1.1 5.6 GO:0005914 spot adherens junction(GO:0005914)
1.1 4.3 GO:0002111 BRCA2-BRAF35 complex(GO:0002111)
0.6 4.3 GO:0000235 astral microtubule(GO:0000235)
0.6 2.4 GO:0098835 presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835)
0.5 6.5 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.5 5.4 GO:0030314 junctional membrane complex(GO:0030314)
0.5 13.1 GO:0031616 spindle pole centrosome(GO:0031616)
0.4 1.5 GO:0097169 AIM2 inflammasome complex(GO:0097169)
0.3 5.7 GO:0005641 nuclear envelope lumen(GO:0005641)
0.3 1.6 GO:0035189 Rb-E2F complex(GO:0035189)
0.3 4.2 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.3 2.8 GO:0033093 Weibel-Palade body(GO:0033093)
0.2 5.1 GO:0031143 pseudopodium(GO:0031143)
0.2 14.9 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.2 1.6 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.2 10.0 GO:0098636 protein complex involved in cell adhesion(GO:0098636)
0.2 0.6 GO:0070557 PCNA-p21 complex(GO:0070557)
0.2 14.5 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.2 7.2 GO:0045095 keratin filament(GO:0045095)
0.1 8.1 GO:0001533 cornified envelope(GO:0001533)
0.1 4.8 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.1 8.2 GO:0031901 early endosome membrane(GO:0031901)
0.1 7.7 GO:0000791 euchromatin(GO:0000791)
0.1 1.5 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.1 1.3 GO:0097524 sperm plasma membrane(GO:0097524)
0.1 5.4 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.1 7.0 GO:0031941 filamentous actin(GO:0031941)
0.1 12.2 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.1 1.3 GO:0044327 dendritic spine head(GO:0044327)
0.1 20.6 GO:0031225 anchored component of membrane(GO:0031225)
0.1 0.9 GO:0097451 glial limiting end-foot(GO:0097451)
0.1 1.2 GO:0043220 Schmidt-Lanterman incisure(GO:0043220)
0.0 0.6 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 6.7 GO:0045111 intermediate filament cytoskeleton(GO:0045111)
0.0 0.9 GO:0000145 exocyst(GO:0000145)
0.0 4.2 GO:0005811 lipid particle(GO:0005811)
0.0 2.8 GO:0005871 kinesin complex(GO:0005871)
0.0 1.2 GO:0097440 apical dendrite(GO:0097440)
0.0 0.7 GO:0044292 dendrite terminus(GO:0044292)
0.0 2.2 GO:0031519 PcG protein complex(GO:0031519)
0.0 0.4 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 6.7 GO:0072562 blood microparticle(GO:0072562)
0.0 2.7 GO:0005901 caveola(GO:0005901)
0.0 41.6 GO:0005615 extracellular space(GO:0005615)
0.0 5.6 GO:0031012 extracellular matrix(GO:0031012)
0.0 1.5 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 9.5 GO:0005911 cell-cell junction(GO:0005911)
0.0 6.1 GO:0031965 nuclear membrane(GO:0031965)
0.0 5.3 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 2.7 GO:0005925 focal adhesion(GO:0005925)
0.0 35.9 GO:0070062 extracellular exosome(GO:0070062)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.7 23.9 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
2.6 7.7 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
2.0 8.0 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
2.0 5.9 GO:0042015 interleukin-20 binding(GO:0042015)
1.7 8.4 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
1.5 4.6 GO:0030338 CMP-N-acetylneuraminate monooxygenase activity(GO:0030338)
1.5 9.1 GO:0047844 deoxycytidine deaminase activity(GO:0047844)
1.2 9.7 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
1.1 5.7 GO:0004051 arachidonate 5-lipoxygenase activity(GO:0004051)
1.1 7.8 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
1.1 5.4 GO:0004974 leukotriene receptor activity(GO:0004974)
0.9 6.3 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.9 3.4 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
0.8 3.3 GO:0004450 isocitrate dehydrogenase (NADP+) activity(GO:0004450)
0.7 2.8 GO:0008184 glycogen phosphorylase activity(GO:0008184)
0.6 6.9 GO:0004859 phospholipase inhibitor activity(GO:0004859)
0.6 8.3 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.6 7.4 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.5 6.4 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.5 6.5 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.5 3.8 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.5 9.9 GO:0032036 myosin heavy chain binding(GO:0032036)
0.4 4.5 GO:0008494 translation activator activity(GO:0008494)
0.4 4.4 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.4 2.4 GO:0008384 IkappaB kinase activity(GO:0008384)
0.4 1.5 GO:0015222 serotonin transmembrane transporter activity(GO:0015222)
0.3 5.6 GO:0045294 alpha-catenin binding(GO:0045294)
0.3 2.3 GO:0050694 galactose 3-O-sulfotransferase activity(GO:0050694)
0.3 2.2 GO:0019958 C-X-C chemokine binding(GO:0019958)
0.3 3.7 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.3 1.2 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.3 1.5 GO:0097153 cysteine-type endopeptidase activity involved in apoptotic process(GO:0097153)
0.3 0.9 GO:0070051 fibrinogen binding(GO:0070051)
0.3 5.4 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.3 1.6 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.3 8.0 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.2 10.4 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.2 1.4 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.2 4.8 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.2 2.7 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.2 7.7 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.2 6.2 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.2 0.8 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.2 4.5 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.2 1.5 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.2 0.6 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.2 1.6 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.2 4.3 GO:0000400 four-way junction DNA binding(GO:0000400)
0.2 2.2 GO:0001055 RNA polymerase II activity(GO:0001055)
0.2 0.7 GO:0002046 opsin binding(GO:0002046)
0.2 2.3 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.2 2.6 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.2 2.9 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.1 4.1 GO:0004190 aspartic-type endopeptidase activity(GO:0004190)
0.1 3.3 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.1 4.2 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.1 1.3 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 1.6 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.1 0.7 GO:0016018 cyclosporin A binding(GO:0016018)
0.1 0.9 GO:0005131 growth hormone receptor binding(GO:0005131)
0.1 6.5 GO:0048487 beta-tubulin binding(GO:0048487)
0.1 5.1 GO:0001786 phosphatidylserine binding(GO:0001786)
0.1 3.9 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.1 6.6 GO:0070888 E-box binding(GO:0070888)
0.1 2.1 GO:0016594 glycine binding(GO:0016594)
0.1 11.4 GO:0031490 chromatin DNA binding(GO:0031490)
0.1 7.0 GO:0003777 microtubule motor activity(GO:0003777)
0.1 2.0 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.1 0.2 GO:0004493 methylmalonyl-CoA epimerase activity(GO:0004493)
0.1 1.7 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.1 0.7 GO:0048531 beta-1,3-galactosyltransferase activity(GO:0048531)
0.1 2.4 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.1 14.6 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 9.3 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 1.0 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 7.3 GO:0005178 integrin binding(GO:0005178)
0.0 7.6 GO:0052689 carboxylic ester hydrolase activity(GO:0052689)
0.0 0.7 GO:0005123 death receptor binding(GO:0005123)
0.0 0.9 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.2 GO:0019961 interferon binding(GO:0019961)
0.0 0.5 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.2 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.0 2.9 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 1.1 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 13.2 GO:0008047 enzyme activator activity(GO:0008047)
0.0 0.2 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 12.4 GO:0003779 actin binding(GO:0003779)
0.0 0.9 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 4.8 GO:0044822 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 1.8 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds(GO:0004553)
0.0 0.3 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
0.0 3.3 GO:0045296 cadherin binding(GO:0045296)
0.0 3.4 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 50.2 PID RHOA REG PATHWAY Regulation of RhoA activity
0.3 7.7 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.3 9.7 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.3 21.7 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.2 10.1 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.2 2.4 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.1 15.6 PID IL4 2PATHWAY IL4-mediated signaling events
0.1 5.1 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1 3.8 ST G ALPHA S PATHWAY G alpha s Pathway
0.1 5.9 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.1 12.4 PID E2F PATHWAY E2F transcription factor network
0.1 4.8 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.1 3.6 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.1 7.6 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 3.2 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.0 0.9 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 3.7 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 0.9 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.0 0.9 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.0 1.3 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.0 0.9 PID INSULIN PATHWAY Insulin Pathway
0.0 1.3 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.4 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 6.3 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.4 6.5 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.4 5.4 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.3 5.9 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.3 7.4 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.3 1.6 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.3 3.8 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.2 0.7 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.2 7.8 REACTOME KINESINS Genes involved in Kinesins
0.2 7.0 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.2 11.2 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.2 3.2 REACTOME CTLA4 INHIBITORY SIGNALING Genes involved in CTLA4 inhibitory signaling
0.2 4.0 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.2 1.5 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.2 4.5 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.2 20.5 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.2 2.4 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.2 2.7 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.2 9.9 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.1 5.1 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.1 2.8 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.1 2.4 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.1 30.1 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.1 2.1 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.1 2.2 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.1 2.1 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.1 1.2 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 4.8 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.1 1.5 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.1 3.3 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.1 1.4 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1 0.9 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.1 1.6 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.1 2.9 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 4.8 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 3.3 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.9 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.6 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.8 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 4.3 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 1.3 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.0 1.6 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.2 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.8 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors