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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Trp73

Z-value: 0.60

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Transcription factors associated with Trp73

Gene Symbol Gene ID Gene Info
Trp73
ENSMUSG00000029026.18 Trp73

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Trp73mm39_v1_chr4_-_154181562_154181630-0.218.0e-02Click!

Activity profile of Trp73 motif

Sorted Z-values of Trp73 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Trp73

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr7_+_30487322 3.50 ENSMUST00000189673.7
ENSMUST00000190990.7
ENSMUST00000189962.7
ENSMUST00000187493.7
ENSMUST00000098559.3
Krtdap
keratinocyte differentiation associated protein
chr5_+_64960705 3.12 ENSMUST00000165536.8
Klf3
Kruppel-like factor 3 (basic)
chr11_-_69838971 2.92 ENSMUST00000179298.3
ENSMUST00000018710.13
ENSMUST00000135437.3
ENSMUST00000141837.9
ENSMUST00000142500.8
Slc2a4
solute carrier family 2 (facilitated glucose transporter), member 4
chr7_-_19530714 2.80 ENSMUST00000108449.9
ENSMUST00000043822.8
Cblc
Casitas B-lineage lymphoma c
chr11_-_103235475 2.73 ENSMUST00000041385.14
Arhgap27
Rho GTPase activating protein 27
chr2_+_119068012 2.56 ENSMUST00000110817.3
Spint1
serine protease inhibitor, Kunitz type 1
chr2_+_119067832 2.53 ENSMUST00000028783.14
Spint1
serine protease inhibitor, Kunitz type 1
chr2_+_119067929 2.52 ENSMUST00000110816.8
Spint1
serine protease inhibitor, Kunitz type 1
chr4_-_49451134 2.44 ENSMUST00000107697.2
ENSMUST00000095086.3
Acnat1
acyl-coenzyme A amino acid N-acyltransferase 1
chr3_+_159545309 2.37 ENSMUST00000068952.10
ENSMUST00000198878.2
Wls
wntless WNT ligand secretion mediator
chr8_-_71112295 2.27 ENSMUST00000211715.2
ENSMUST00000210307.2
ENSMUST00000209768.2
ENSMUST00000070173.9
Pgpep1
pyroglutamyl-peptidase I
chr2_-_127383305 2.17 ENSMUST00000103214.3
Prom2
prominin 2
chr5_-_103777145 2.16 ENSMUST00000031263.2
Slc10a6
solute carrier family 10 (sodium/bile acid cotransporter family), member 6
chr2_-_127383332 2.11 ENSMUST00000028855.14
Prom2
prominin 2
chr17_+_28451674 2.11 ENSMUST00000002320.16
ENSMUST00000232879.2
ENSMUST00000166744.8
Ppard
peroxisome proliferator activator receptor delta
chr17_+_23883974 2.10 ENSMUST00000233541.2
Bicdl2
BICD family like cargo adaptor 2
chr15_+_98953044 1.82 ENSMUST00000230021.2
ENSMUST00000047104.15
ENSMUST00000024249.5
Prph
peripherin
chr18_-_32170012 1.81 ENSMUST00000134663.2
Myo7b
myosin VIIB
chr14_+_33807935 1.79 ENSMUST00000022519.15
Anxa8
annexin A8
chr14_+_33807964 1.76 ENSMUST00000120077.2
Anxa8
annexin A8
chr4_-_106662195 1.75 ENSMUST00000065253.13
Acot11
acyl-CoA thioesterase 11
chr14_+_70793340 1.74 ENSMUST00000163060.2
Hr
lysine demethylase and nuclear receptor corepressor
chr10_+_127478844 1.72 ENSMUST00000092074.12
ENSMUST00000120279.2
Stat6
signal transducer and activator of transcription 6
chr2_+_74522258 1.66 ENSMUST00000061745.5
Hoxd10
homeobox D10
chr15_-_98505508 1.58 ENSMUST00000096224.6
Adcy6
adenylate cyclase 6
chr1_+_134217727 1.54 ENSMUST00000027730.6
Myog
myogenin
chr2_-_164699462 1.53 ENSMUST00000109316.8
ENSMUST00000156255.8
ENSMUST00000128110.2
ENSMUST00000109317.10
ENSMUST00000059954.14
Pltp
phospholipid transfer protein
chr11_+_32246489 1.46 ENSMUST00000093207.4
Hba-a2
hemoglobin alpha, adult chain 2
chr10_+_69761597 1.38 ENSMUST00000182269.8
ENSMUST00000183261.8
ENSMUST00000183074.8
Ank3
ankyrin 3, epithelial
chr5_+_137286535 1.36 ENSMUST00000024099.11
ENSMUST00000196208.5
ENSMUST00000085934.4
Ache
acetylcholinesterase
chr19_-_34724689 1.35 ENSMUST00000009522.4
Slc16a12
solute carrier family 16 (monocarboxylic acid transporters), member 12
chr7_+_26819334 1.34 ENSMUST00000003100.10
Cyp2f2
cytochrome P450, family 2, subfamily f, polypeptide 2
chr4_-_87724533 1.31 ENSMUST00000126353.8
ENSMUST00000149357.8
Mllt3
myeloid/lymphoid or mixed-lineage leukemia; translocated to, 3
chr4_-_87724512 1.30 ENSMUST00000148059.2
Mllt3
myeloid/lymphoid or mixed-lineage leukemia; translocated to, 3
chr6_-_29212239 1.25 ENSMUST00000160878.8
Impdh1
inosine monophosphate dehydrogenase 1
chr10_+_75242745 1.25 ENSMUST00000039925.8
Upb1
ureidopropionase, beta
chr2_-_90735171 1.24 ENSMUST00000005647.4
Ndufs3
NADH:ubiquinone oxidoreductase core subunit S3
chr9_-_58065800 1.20 ENSMUST00000168864.4
Islr
immunoglobulin superfamily containing leucine-rich repeat
chr11_-_76359222 1.18 ENSMUST00000065028.14
Abr
active BCR-related gene
chr1_-_136188611 1.16 ENSMUST00000086395.7
Gpr25
G protein-coupled receptor 25
chr10_+_52267702 1.13 ENSMUST00000067085.7
Nepn
nephrocan
chr6_-_29212295 1.11 ENSMUST00000078155.12
Impdh1
inosine monophosphate dehydrogenase 1
chr11_+_32233511 1.11 ENSMUST00000093209.4
Hba-a1
hemoglobin alpha, adult chain 1
chr1_+_55127110 1.10 ENSMUST00000075242.7
Hspe1
heat shock protein 1 (chaperonin 10)
chr4_-_141125885 1.09 ENSMUST00000133676.3
ENSMUST00000042617.14
Clcnka
chloride channel, voltage-sensitive Ka
chr1_-_55127183 1.08 ENSMUST00000027123.15
Hspd1
heat shock protein 1 (chaperonin)
chr1_-_55127312 1.06 ENSMUST00000127861.8
ENSMUST00000144077.3
Hspd1
heat shock protein 1 (chaperonin)
chr4_-_49383576 1.03 ENSMUST00000107698.8
Acnat2
acyl-coenzyme A amino acid N-acyltransferase 2
chr10_+_69761630 0.99 ENSMUST00000182029.8
Ank3
ankyrin 3, epithelial
chr3_+_28752050 0.98 ENSMUST00000029240.14
Slc2a2
solute carrier family 2 (facilitated glucose transporter), member 2
chr11_-_89587671 0.98 ENSMUST00000128717.9
Ankfn1
ankyrin-repeat and fibronectin type III domain containing 1
chr10_+_69761314 0.95 ENSMUST00000182692.8
ENSMUST00000092433.12
Ank3
ankyrin 3, epithelial
chr11_+_97917746 0.93 ENSMUST00000017548.7
Rpl19
ribosomal protein L19
chr19_-_47146203 0.89 ENSMUST00000178630.2
Calhm3
calcium homeostasis modulator 3
chr8_+_27575611 0.88 ENSMUST00000178514.8
ENSMUST00000033876.14
Adgra2
adhesion G protein-coupled receptor A2
chr16_+_10297923 0.87 ENSMUST00000230395.2
Ciita
class II transactivator
chr3_+_89153258 0.87 ENSMUST00000040888.12
Krtcap2
keratinocyte associated protein 2
chr17_+_28910714 0.85 ENSMUST00000233250.2
Mapk14
mitogen-activated protein kinase 14
chr5_+_135698881 0.81 ENSMUST00000153500.8
Por
P450 (cytochrome) oxidoreductase
chr7_+_140462343 0.79 ENSMUST00000163610.9
ENSMUST00000164681.8
Psmd13
proteasome (prosome, macropain) 26S subunit, non-ATPase, 13
chr12_-_45120895 0.79 ENSMUST00000120531.8
ENSMUST00000143376.8
Stxbp6
syntaxin binding protein 6 (amisyn)
chr2_-_91854844 0.79 ENSMUST00000028663.5
Creb3l1
cAMP responsive element binding protein 3-like 1
chr17_+_29309942 0.78 ENSMUST00000119901.9
Cdkn1a
cyclin-dependent kinase inhibitor 1A (P21)
chr16_+_10298011 0.76 ENSMUST00000230450.2
Ciita
class II transactivator
chr5_-_31117617 0.75 ENSMUST00000202567.2
ENSMUST00000074840.12
Preb
prolactin regulatory element binding
chr19_+_46293160 0.75 ENSMUST00000073116.13
Nfkb2
nuclear factor of kappa light polypeptide gene enhancer in B cells 2, p49/p100
chr7_+_140461860 0.74 ENSMUST00000026560.14
Psmd13
proteasome (prosome, macropain) 26S subunit, non-ATPase, 13
chr9_+_108539296 0.74 ENSMUST00000035222.6
Slc25a20
solute carrier family 25 (mitochondrial carnitine/acylcarnitine translocase), member 20
chr9_-_44624496 0.73 ENSMUST00000144251.8
ENSMUST00000156918.8
Phldb1
pleckstrin homology like domain, family B, member 1
chr10_-_67384898 0.72 ENSMUST00000075686.7
Ado
2-aminoethanethiol (cysteamine) dioxygenase
chr19_+_46293210 0.71 ENSMUST00000236591.2
Nfkb2
nuclear factor of kappa light polypeptide gene enhancer in B cells 2, p49/p100
chr5_-_33940053 0.70 ENSMUST00000148451.2
ENSMUST00000005431.6
Letm1
leucine zipper-EF-hand containing transmembrane protein 1
chr4_+_32238712 0.69 ENSMUST00000108180.9
Bach2
BTB and CNC homology, basic leucine zipper transcription factor 2
chr9_+_121245036 0.68 ENSMUST00000211187.2
Trak1
trafficking protein, kinesin binding 1
chrX_-_108056995 0.67 ENSMUST00000033597.9
Hmgn5
high-mobility group nucleosome binding domain 5
chr11_-_33528933 0.66 ENSMUST00000020366.8
ENSMUST00000135350.2
Gabrp
gamma-aminobutyric acid (GABA) A receptor, pi
chr2_-_170339061 0.65 ENSMUST00000038824.6
Cyp24a1
cytochrome P450, family 24, subfamily a, polypeptide 1
chr9_-_32454157 0.65 ENSMUST00000183767.2
Fli1
Friend leukemia integration 1
chr18_-_36201664 0.60 ENSMUST00000239409.2
Nrg2
neuregulin 2
chr11_-_95037089 0.56 ENSMUST00000021241.8
Dlx4
distal-less homeobox 4
chr7_-_4517367 0.56 ENSMUST00000166161.8
Tnnt1
troponin T1, skeletal, slow
chr4_+_119396913 0.55 ENSMUST00000137560.8
Foxj3
forkhead box J3
chr16_+_4964849 0.52 ENSMUST00000165810.2
ENSMUST00000230616.2
Sec14l5
SEC14-like lipid binding 5
chr4_+_100926170 0.52 ENSMUST00000106955.2
ENSMUST00000038463.15
Raver2
ribonucleoprotein, PTB-binding 2
chr2_+_160573178 0.50 ENSMUST00000103115.8
Plcg1
phospholipase C, gamma 1
chr11_+_60030891 0.50 ENSMUST00000171108.8
ENSMUST00000090806.5
Rai1
retinoic acid induced 1
chr1_-_170042947 0.49 ENSMUST00000027979.14
ENSMUST00000123399.2
Uhmk1
U2AF homology motif (UHM) kinase 1
chr14_+_53607470 0.47 ENSMUST00000103652.5
Trav14n-3
T cell receptor alpha variable 14N-3
chr6_+_40548291 0.46 ENSMUST00000051540.5
Olfr460
olfactory receptor 460
chr19_-_7460550 0.45 ENSMUST00000088169.7
Rtn3
reticulon 3
chr2_+_160573604 0.44 ENSMUST00000174885.2
ENSMUST00000109462.8
Plcg1
phospholipase C, gamma 1
chr10_-_57408585 0.42 ENSMUST00000020027.11
Serinc1
serine incorporator 1
chr7_+_120411588 0.42 ENSMUST00000208668.2
Gm5737
predicted gene 5737
chr11_-_99869879 0.41 ENSMUST00000105051.2
Krtap29-1
keratin associated protein 29-1
chr10_+_115854118 0.40 ENSMUST00000063470.11
Ptprr
protein tyrosine phosphatase, receptor type, R
chr18_+_56565188 0.38 ENSMUST00000070166.6
Gramd3
GRAM domain containing 3
chr6_-_97464761 0.37 ENSMUST00000032146.14
Frmd4b
FERM domain containing 4B
chr11_+_69914746 0.37 ENSMUST00000124568.10
Dlg4
discs large MAGUK scaffold protein 4
chr2_+_127112127 0.34 ENSMUST00000110375.9
Stard7
START domain containing 7
chr19_-_7460600 0.34 ENSMUST00000235593.2
ENSMUST00000088171.12
ENSMUST00000065304.13
ENSMUST00000025667.14
Rtn3
reticulon 3
chr7_-_4517608 0.33 ENSMUST00000166959.8
Tnnt1
troponin T1, skeletal, slow
chr1_+_167445815 0.32 ENSMUST00000111380.2
Rxrg
retinoid X receptor gamma
chr19_+_41900360 0.30 ENSMUST00000011896.8
Pgam1
phosphoglycerate mutase 1
chr10_-_62486948 0.29 ENSMUST00000020270.6
Ddx50
DExD box helicase 50
chr10_+_105676925 0.27 ENSMUST00000020049.9
Ccdc59
coiled-coil domain containing 59
chr5_-_139805661 0.26 ENSMUST00000147328.2
Tmem184a
transmembrane protein 184a
chr6_-_97408367 0.25 ENSMUST00000124050.3
Frmd4b
FERM domain containing 4B
chrX_+_102365004 0.25 ENSMUST00000033689.3
Cdx4
caudal type homeobox 4
chr11_+_75546989 0.23 ENSMUST00000136935.2
Myo1c
myosin IC
chr6_+_41095752 0.22 ENSMUST00000103269.3
Trbv12-2
T cell receptor beta, variable 12-2
chr9_-_42383494 0.22 ENSMUST00000128959.8
ENSMUST00000066148.12
ENSMUST00000138506.8
Tbcel
tubulin folding cofactor E-like
chr10_-_57408512 0.17 ENSMUST00000169122.8
Serinc1
serine incorporator 1
chr7_-_4517559 0.14 ENSMUST00000163538.8
Tnnt1
troponin T1, skeletal, slow
chr17_-_46513499 0.14 ENSMUST00000024749.9
Polh
polymerase (DNA directed), eta (RAD 30 related)
chr9_+_101815680 0.13 ENSMUST00000112841.2
9630041A04Rik
RIKEN cDNA 9630041A04 gene
chr10_+_110581293 0.11 ENSMUST00000174857.8
ENSMUST00000073781.12
ENSMUST00000173471.8
ENSMUST00000173634.2
E2f7
E2F transcription factor 7
chr16_+_35891991 0.10 ENSMUST00000164916.9
Ccdc58
coiled-coil domain containing 58
chr7_-_141023199 0.10 ENSMUST00000106005.9
Pidd1
p53 induced death domain protein 1
chr14_-_52341426 0.08 ENSMUST00000227536.2
ENSMUST00000227195.2
ENSMUST00000228815.2
ENSMUST00000228198.2
ENSMUST00000227458.2
ENSMUST00000228232.2
ENSMUST00000227242.2
ENSMUST00000228748.2
Hnrnpc
heterogeneous nuclear ribonucleoprotein C
chr2_-_114031897 0.07 ENSMUST00000050668.4
Zfp770
zinc finger protein 770
chr12_+_111540920 0.06 ENSMUST00000075281.8
ENSMUST00000084953.13
Mark3
MAP/microtubule affinity regulating kinase 3
chr19_+_46292759 0.06 ENSMUST00000237330.2
Nfkb2
nuclear factor of kappa light polypeptide gene enhancer in B cells 2, p49/p100
chr14_+_52818032 0.06 ENSMUST00000103569.3
Trav3-1
T cell receptor alpha variable 3-1
chr19_+_53317844 0.05 ENSMUST00000111737.3
ENSMUST00000025998.15
ENSMUST00000237837.2
Mxi1
MAX interactor 1, dimerization protein
chr14_-_24295988 0.04 ENSMUST00000073687.13
ENSMUST00000090398.11
Dlg5
discs large MAGUK scaffold protein 5
chr16_-_56748424 0.04 ENSMUST00000210579.2
Lnp1
leukemia NUP98 fusion partner 1
chr3_+_53396120 0.03 ENSMUST00000029307.4
Stoml3
stomatin (Epb7.2)-like 3
chr12_+_3415107 0.03 ENSMUST00000220210.2
Kif3c
kinesin family member 3C
chr2_+_59442378 0.02 ENSMUST00000112568.8
ENSMUST00000037526.11
Tanc1
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1
chr1_+_185095232 0.00 ENSMUST00000046514.13
Eprs
glutamyl-prolyl-tRNA synthetase

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 4.3 GO:2001287 negative regulation of caveolin-mediated endocytosis(GO:2001287)
0.8 2.4 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.7 2.1 GO:0045041 protein import into mitochondrial intermembrane space(GO:0045041)
0.5 1.6 GO:1904117 response to vasopressin(GO:1904116) cellular response to vasopressin(GO:1904117)
0.5 1.5 GO:0014737 positive regulation of muscle atrophy(GO:0014737) response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
0.5 1.4 GO:0045212 neurotransmitter receptor biosynthetic process(GO:0045212)
0.4 1.3 GO:0015881 creatine transport(GO:0015881)
0.4 1.3 GO:0090420 naphthalene metabolic process(GO:0018931) naphthalene-containing compound metabolic process(GO:0090420)
0.4 1.7 GO:0035771 T-helper 1 cell lineage commitment(GO:0002296) interleukin-4-mediated signaling pathway(GO:0035771)
0.4 1.5 GO:0042360 vitamin E metabolic process(GO:0042360)
0.4 1.8 GO:1904970 brush border assembly(GO:1904970)
0.4 7.6 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.3 2.4 GO:0006177 GMP biosynthetic process(GO:0006177)
0.3 1.5 GO:0002266 follicular dendritic cell activation(GO:0002266) follicular dendritic cell differentiation(GO:0002268)
0.3 3.3 GO:0072658 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660)
0.3 1.3 GO:0019482 beta-alanine metabolic process(GO:0019482)
0.2 2.1 GO:0006776 vitamin A metabolic process(GO:0006776)
0.2 0.8 GO:0046210 nitrate catabolic process(GO:0043602) nitric oxide catabolic process(GO:0046210) cellular organohalogen metabolic process(GO:0090345) cellular organofluorine metabolic process(GO:0090346)
0.2 1.0 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.2 1.1 GO:0072053 renal inner medulla development(GO:0072053)
0.2 0.9 GO:0090210 regulation of establishment of blood-brain barrier(GO:0090210)
0.2 1.0 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.2 1.6 GO:0045348 positive regulation of MHC class II biosynthetic process(GO:0045348)
0.2 0.8 GO:0070278 extracellular matrix constituent secretion(GO:0070278)
0.1 1.2 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314) negative regulation of blood vessel remodeling(GO:0060313)
0.1 0.7 GO:0098957 anterograde axonal transport of mitochondrion(GO:0098957)
0.1 2.6 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.1 0.9 GO:0014835 myoblast differentiation involved in skeletal muscle regeneration(GO:0014835) positive regulation of interleukin-12 secretion(GO:2001184)
0.1 0.8 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.1 2.8 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.1 1.5 GO:0043248 proteasome assembly(GO:0043248)
0.1 2.9 GO:0044381 glucose import in response to insulin stimulus(GO:0044381)
0.1 0.8 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.1 0.6 GO:1904222 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.1 1.7 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.1 0.7 GO:0034214 protein hexamerization(GO:0034214)
0.1 1.0 GO:0050957 equilibrioception(GO:0050957)
0.1 0.8 GO:0048207 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.1 1.7 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.1 0.4 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.1 0.7 GO:0015879 carnitine transport(GO:0015879)
0.1 0.9 GO:1901339 regulation of store-operated calcium channel activity(GO:1901339)
0.1 1.1 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0 0.3 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.0 0.9 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977)
0.0 0.7 GO:1904259 regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
0.0 5.2 GO:0006637 acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.0 0.3 GO:0018992 germ-line sex determination(GO:0018992)
0.0 2.5 GO:0048821 erythrocyte development(GO:0048821)
0.0 0.1 GO:0032877 positive regulation of DNA endoreduplication(GO:0032877)
0.0 0.6 GO:0033280 response to vitamin D(GO:0033280)
0.0 0.9 GO:0018195 peptidyl-arginine modification(GO:0018195)
0.0 1.8 GO:0045104 intermediate filament cytoskeleton organization(GO:0045104)
0.0 0.2 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.0 0.1 GO:0090367 negative regulation of mRNA modification(GO:0090367)
0.0 0.4 GO:0098970 receptor diffusion trapping(GO:0098953) postsynaptic neurotransmitter receptor diffusion trapping(GO:0098970) neurotransmitter receptor diffusion trapping(GO:0099628)
0.0 0.6 GO:0035855 megakaryocyte development(GO:0035855)
0.0 0.1 GO:0006290 pyrimidine dimer repair(GO:0006290)
0.0 0.5 GO:0045948 positive regulation of translational initiation(GO:0045948)
0.0 3.6 GO:0007596 blood coagulation(GO:0007596)
0.0 1.1 GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512)
0.0 0.5 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 0.6 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.0 GO:0045186 zonula adherens assembly(GO:0045186)
0.0 0.1 GO:0035331 negative regulation of hippo signaling(GO:0035331)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 4.3 GO:0044393 microspike(GO:0044393)
0.5 2.6 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.3 1.5 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.3 2.1 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.3 0.8 GO:0070557 PCNA-p21 complex(GO:0070557)
0.2 1.8 GO:0044299 C-fiber(GO:0044299)
0.2 3.5 GO:0042599 lamellar body(GO:0042599)
0.2 2.9 GO:0032593 insulin-responsive compartment(GO:0032593)
0.1 1.5 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.1 3.3 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.1 1.4 GO:0043083 synaptic cleft(GO:0043083)
0.1 0.9 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.1 3.2 GO:0032839 dendrite cytoplasm(GO:0032839)
0.1 1.6 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.1 3.6 GO:0031902 late endosome membrane(GO:0031902)
0.1 1.0 GO:0005861 troponin complex(GO:0005861)
0.0 0.2 GO:0045160 myosin I complex(GO:0045160)
0.0 0.7 GO:0045180 basal cortex(GO:0045180)
0.0 2.2 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.8 GO:0000145 exocyst(GO:0000145)
0.0 0.7 GO:1904115 axon cytoplasm(GO:1904115)
0.0 1.2 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.7 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 0.8 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 0.9 GO:0008180 COP9 signalosome(GO:0008180)
0.0 1.8 GO:0016459 myosin complex(GO:0016459)
0.0 3.5 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 0.7 GO:0034707 chloride channel complex(GO:0034707)
0.0 1.6 GO:0016605 PML body(GO:0016605)
0.0 1.7 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.9 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.9 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.7 2.1 GO:0016501 prostacyclin receptor activity(GO:0016501)
0.6 2.6 GO:0031720 haptoglobin binding(GO:0031720)
0.5 1.4 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.4 1.3 GO:0005308 creatine transmembrane transporter activity(GO:0005308)
0.4 2.4 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.4 2.1 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.3 0.8 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.2 0.9 GO:1990932 5.8S rRNA binding(GO:1990932)
0.2 1.6 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.2 0.8 GO:0008941 nitric oxide dioxygenase activity(GO:0008941) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor(GO:0016708) iron-cytochrome-c reductase activity(GO:0047726)
0.2 5.2 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.2 2.4 GO:0031852 mu-type opioid receptor binding(GO:0031852)
0.2 0.6 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.1 2.3 GO:0008242 omega peptidase activity(GO:0008242)
0.1 0.7 GO:0015226 amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.1 1.7 GO:0042809 vitamin D receptor binding(GO:0042809)
0.1 0.3 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.1 1.0 GO:0031014 troponin T binding(GO:0031014)
0.1 0.3 GO:0004082 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.1 0.9 GO:0004576 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.1 3.6 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.1 0.9 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
0.1 1.3 GO:0019825 oxygen binding(GO:0019825)
0.1 2.8 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.1 0.9 GO:0051525 NFAT protein binding(GO:0051525)
0.1 4.3 GO:0015485 cholesterol binding(GO:0015485)
0.1 0.4 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.0 1.1 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.6 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 7.6 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.7 GO:0015368 calcium:cation antiporter activity(GO:0015368)
0.0 1.2 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.7 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.8 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.5 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 3.3 GO:0030507 spectrin binding(GO:0030507)
0.0 0.8 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.7 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.7 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.7 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 1.5 GO:0070888 E-box binding(GO:0070888)
0.0 0.7 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 1.6 GO:0033613 activating transcription factor binding(GO:0033613)
0.0 1.7 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 0.8 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.6 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.0 2.7 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.5 GO:0035326 enhancer binding(GO:0035326)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1 2.9 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.1 1.6 PID LPA4 PATHWAY LPA4-mediated signaling events
0.1 2.1 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 1.7 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.0 0.9 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 2.4 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 2.4 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 0.6 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 3.6 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.0 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 1.8 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.7 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 0.4 ST GA12 PATHWAY G alpha 12 Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.9 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.1 2.4 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1 2.2 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 1.6 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.1 1.5 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.1 0.9 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.1 3.3 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 1.3 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.1 1.5 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.1 0.9 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 1.4 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 2.1 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 2.3 REACTOME P53 DEPENDENT G1 DNA DAMAGE RESPONSE Genes involved in p53-Dependent G1 DNA Damage Response
0.0 0.7 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 1.5 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 2.4 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.6 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 1.6 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.6 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 1.2 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 1.0 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.8 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 1.7 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction