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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Twist1

Z-value: 0.93

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Transcription factors associated with Twist1

Gene Symbol Gene ID Gene Info
Twist1
ENSMUSG00000035799.7 Twist1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Twist1mm39_v1_chr12_+_34007645_340076700.301.1e-02Click!

Activity profile of Twist1 motif

Sorted Z-values of Twist1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Twist1

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr6_-_41012435 5.51 ENSMUST00000031931.6
2210010C04Rik
RIKEN cDNA 2210010C04 gene
chr6_+_30639217 4.84 ENSMUST00000031806.10
Cpa1
carboxypeptidase A1, pancreatic
chr17_+_34029484 4.49 ENSMUST00000048560.11
ENSMUST00000172649.8
ENSMUST00000173789.2
Kank3
KN motif and ankyrin repeat domains 3
chr2_+_71811526 4.04 ENSMUST00000090826.12
ENSMUST00000102698.10
Rapgef4
Rap guanine nucleotide exchange factor (GEF) 4
chr11_-_46203047 3.72 ENSMUST00000129474.2
ENSMUST00000093166.11
ENSMUST00000165599.9
Cyfip2
cytoplasmic FMR1 interacting protein 2
chr9_-_54569128 3.52 ENSMUST00000034822.12
Acsbg1
acyl-CoA synthetase bubblegum family member 1
chr8_+_55024446 3.43 ENSMUST00000239166.2
ENSMUST00000239106.2
ENSMUST00000239152.2
Asb5
ankyrin repeat and SOCs box-containing 5
chr19_-_11243530 3.30 ENSMUST00000169159.3
Ms4a1
membrane-spanning 4-domains, subfamily A, member 1
chr5_+_8943943 3.22 ENSMUST00000196067.2
Abcb4
ATP-binding cassette, sub-family B (MDR/TAP), member 4
chr4_+_155553571 3.21 ENSMUST00000178188.8
ENSMUST00000178238.8
ENSMUST00000023920.3
Tmem52
transmembrane protein 52
chr8_-_106660470 3.11 ENSMUST00000034368.8
Ctrl
chymotrypsin-like
chr8_+_93084253 2.58 ENSMUST00000210246.2
ENSMUST00000034184.12
Irx5
Iroquois homeobox 5
chr5_+_24569802 2.54 ENSMUST00000115090.6
ENSMUST00000030834.7
Nos3
nitric oxide synthase 3, endothelial cell
chr19_+_5790918 2.41 ENSMUST00000081496.6
Ltbp3
latent transforming growth factor beta binding protein 3
chrX_-_56371953 2.36 ENSMUST00000176986.8
Arhgef6
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr17_+_75772475 2.34 ENSMUST00000095204.6
Rasgrp3
RAS, guanyl releasing protein 3
chr7_-_44174065 2.33 ENSMUST00000165208.4
Mybpc2
myosin binding protein C, fast-type
chr9_-_54568950 2.30 ENSMUST00000128624.2
Acsbg1
acyl-CoA synthetase bubblegum family member 1
chr11_-_113600346 2.25 ENSMUST00000173655.8
ENSMUST00000100248.6
Cpsf4l
cleavage and polyadenylation specific factor 4-like
chr10_+_70080913 2.23 ENSMUST00000046807.7
Slc16a9
solute carrier family 16 (monocarboxylic acid transporters), member 9
chr11_+_109541400 2.22 ENSMUST00000106676.8
Prkar1a
protein kinase, cAMP dependent regulatory, type I, alpha
chr8_-_78337297 2.16 ENSMUST00000141202.2
ENSMUST00000152168.8
Tmem184c
transmembrane protein 184C
chr4_-_152122891 2.10 ENSMUST00000030792.2
Tas1r1
taste receptor, type 1, member 1
chr13_-_58261406 2.09 ENSMUST00000160860.9
Klhl3
kelch-like 3
chr4_-_123458465 2.03 ENSMUST00000238731.2
Macf1
microtubule-actin crosslinking factor 1
chr15_-_100497863 2.01 ENSMUST00000073837.13
Pou6f1
POU domain, class 6, transcription factor 1
chrX_-_100310959 2.00 ENSMUST00000135038.2
Il2rg
interleukin 2 receptor, gamma chain
chr9_-_14815228 1.99 ENSMUST00000034409.14
ENSMUST00000117620.8
Izumo1r
IZUMO1 receptor, JUNO
chr16_-_59421342 1.89 ENSMUST00000172910.3
Crybg3
beta-gamma crystallin domain containing 3
chr2_+_31777273 1.81 ENSMUST00000138325.8
ENSMUST00000028187.7
Lamc3
laminin gamma 3
chr18_-_16942289 1.74 ENSMUST00000025166.14
Cdh2
cadherin 2
chr9_+_65172455 1.69 ENSMUST00000048762.8
Cilp
cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
chr18_+_61044830 1.62 ENSMUST00000040359.6
Arsi
arylsulfatase i
chr5_-_23880939 1.62 ENSMUST00000196388.5
Srpk2
serine/arginine-rich protein specific kinase 2
chr4_-_152561896 1.61 ENSMUST00000238738.2
ENSMUST00000162017.3
ENSMUST00000030768.10
Kcnab2
potassium voltage-gated channel, shaker-related subfamily, beta member 2
chr4_-_59915035 1.58 ENSMUST00000030081.2
Slc46a2
solute carrier family 46, member 2
chr9_-_14815050 1.56 ENSMUST00000148155.2
ENSMUST00000121116.8
Izumo1r
IZUMO1 receptor, JUNO
chr7_-_126817639 1.53 ENSMUST00000152267.8
ENSMUST00000106314.8
Septin1
septin 1
chr7_+_45067747 1.52 ENSMUST00000238638.2
Lhb
luteinizing hormone beta
chr7_-_30814652 1.50 ENSMUST00000168884.8
ENSMUST00000108102.9
Hpn
hepsin
chr5_-_35886605 1.48 ENSMUST00000070203.14
Sh3tc1
SH3 domain and tetratricopeptide repeats 1
chr10_+_61010983 1.47 ENSMUST00000143207.8
ENSMUST00000148181.8
ENSMUST00000151886.8
Tbata
thymus, brain and testes associated
chr10_-_126866682 1.46 ENSMUST00000040560.11
Tsfm
Ts translation elongation factor, mitochondrial
chr6_-_29164981 1.44 ENSMUST00000007993.16
Rbm28
RNA binding motif protein 28
chr9_+_57037974 1.40 ENSMUST00000160147.8
ENSMUST00000161663.8
ENSMUST00000034836.16
ENSMUST00000161182.8
Man2c1
mannosidase, alpha, class 2C, member 1
chr5_+_31454787 1.40 ENSMUST00000201166.4
ENSMUST00000072228.9
Gckr
glucokinase regulatory protein
chr19_-_28941264 1.37 ENSMUST00000161813.2
Spata6l
spermatogenesis associated 6 like
chr7_-_126817475 1.34 ENSMUST00000106313.8
ENSMUST00000142356.3
Septin1
septin 1
chr13_+_73775001 1.34 ENSMUST00000022104.9
Tert
telomerase reverse transcriptase
chr10_+_12936248 1.34 ENSMUST00000193426.6
Plagl1
pleiomorphic adenoma gene-like 1
chr6_-_124410452 1.30 ENSMUST00000124998.2
ENSMUST00000238807.2
Clstn3
calsyntenin 3
chr8_+_107237483 1.30 ENSMUST00000080797.8
Cdh3
cadherin 3
chr8_+_123148759 1.30 ENSMUST00000050963.4
Il17c
interleukin 17C
chr2_+_29509704 1.28 ENSMUST00000095087.11
ENSMUST00000091146.12
ENSMUST00000102872.11
ENSMUST00000147755.10
Rapgef1
Rap guanine nucleotide exchange factor (GEF) 1
chr18_+_4920513 1.27 ENSMUST00000126977.8
Svil
supervillin
chr9_-_44253630 1.27 ENSMUST00000097558.5
Hmbs
hydroxymethylbilane synthase
chr12_+_4642987 1.27 ENSMUST00000062580.8
ENSMUST00000220311.2
Itsn2
intersectin 2
chr2_-_45007407 1.26 ENSMUST00000176438.9
Zeb2
zinc finger E-box binding homeobox 2
chr10_-_126866658 1.26 ENSMUST00000120547.2
ENSMUST00000152054.8
Tsfm
Ts translation elongation factor, mitochondrial
chr9_-_114673158 1.21 ENSMUST00000047013.4
Cmtm8
CKLF-like MARVEL transmembrane domain containing 8
chr15_-_72932853 1.19 ENSMUST00000170633.9
ENSMUST00000228960.2
Trappc9
trafficking protein particle complex 9
chr9_-_44253588 1.17 ENSMUST00000215091.2
Hmbs
hydroxymethylbilane synthase
chr11_-_68817875 1.16 ENSMUST00000038932.14
ENSMUST00000125134.2
Odf4
outer dense fiber of sperm tails 4
chr16_+_18630522 1.16 ENSMUST00000115578.10
Ufd1
ubiquitin recognition factor in ER-associated degradation 1
chr11_-_113600838 1.15 ENSMUST00000018871.8
Cpsf4l
cleavage and polyadenylation specific factor 4-like
chr15_-_89007290 1.14 ENSMUST00000109353.9
Tubgcp6
tubulin, gamma complex associated protein 6
chr11_+_87628356 1.14 ENSMUST00000093955.12
Supt4a
SPT4A, DSIF elongation factor subunit
chr2_-_65068917 1.13 ENSMUST00000090896.10
ENSMUST00000155082.2
Cobll1
Cobl-like 1
chr5_+_105667254 1.10 ENSMUST00000067924.13
ENSMUST00000150981.2
Lrrc8c
leucine rich repeat containing 8 family, member C
chr2_+_139520098 1.09 ENSMUST00000184404.8
ENSMUST00000099307.4
Ism1
isthmin 1, angiogenesis inhibitor
chr13_+_55612050 1.08 ENSMUST00000046533.9
Prr7
proline rich 7 (synaptic)
chr7_+_30121776 1.08 ENSMUST00000108175.8
Nfkbid
nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, delta
chr11_+_53410552 1.06 ENSMUST00000108987.8
ENSMUST00000121334.8
ENSMUST00000117061.8
Septin8
septin 8
chr5_-_23881353 1.04 ENSMUST00000198661.5
Srpk2
serine/arginine-rich protein specific kinase 2
chr4_-_129452180 1.03 ENSMUST00000067240.11
Lck
lymphocyte protein tyrosine kinase
chr4_-_129452148 1.03 ENSMUST00000167288.8
ENSMUST00000134336.3
Lck
lymphocyte protein tyrosine kinase
chr5_+_149335214 1.02 ENSMUST00000093110.12
Medag
mesenteric estrogen dependent adipogenesis
chr8_+_72889073 1.02 ENSMUST00000003575.11
Tpm4
tropomyosin 4
chr11_-_94440025 1.01 ENSMUST00000040487.4
Rsad1
radical S-adenosyl methionine domain containing 1
chr9_-_108444561 1.00 ENSMUST00000074208.6
Ndufaf3
NADH:ubiquinone oxidoreductase complex assembly factor 3
chr17_+_34258411 0.97 ENSMUST00000087497.11
ENSMUST00000131134.9
ENSMUST00000235819.2
ENSMUST00000114255.9
ENSMUST00000114252.9
ENSMUST00000237989.2
Col11a2
collagen, type XI, alpha 2
chr2_+_163867370 0.96 ENSMUST00000067715.5
Pabpc1l
poly(A) binding protein, cytoplasmic 1-like
chr6_-_83808717 0.91 ENSMUST00000058383.9
Paip2b
poly(A) binding protein interacting protein 2B
chr8_+_122996308 0.91 ENSMUST00000055537.3
Zfp469
zinc finger protein 469
chr11_+_109541747 0.91 ENSMUST00000049527.7
Prkar1a
protein kinase, cAMP dependent regulatory, type I, alpha
chr7_-_139616538 0.91 ENSMUST00000211638.2
Tubgcp2
tubulin, gamma complex associated protein 2
chr7_+_82516491 0.90 ENSMUST00000082237.7
Mex3b
mex3 RNA binding family member B
chr7_+_130179063 0.89 ENSMUST00000207918.2
ENSMUST00000215492.2
ENSMUST00000084513.12
ENSMUST00000059145.14
Tacc2
transforming, acidic coiled-coil containing protein 2
chrX_-_18327610 0.88 ENSMUST00000044188.5
Dipk2b
divergent protein kinase domain 2B
chr7_-_140596811 0.88 ENSMUST00000081924.5
Ifitm6
interferon induced transmembrane protein 6
chr14_-_70414236 0.87 ENSMUST00000153735.8
Pdlim2
PDZ and LIM domain 2
chr4_+_155875629 0.87 ENSMUST00000105593.2
Ankrd65
ankyrin repeat domain 65
chr13_+_97208069 0.85 ENSMUST00000042517.8
Fam169a
family with sequence similarity 169, member A
chr8_+_53964721 0.82 ENSMUST00000211424.2
ENSMUST00000033920.6
Aga
aspartylglucosaminidase
chr7_+_139616298 0.81 ENSMUST00000168194.3
ENSMUST00000210882.2
Zfp511
zinc finger protein 511
chr9_-_14815163 0.77 ENSMUST00000069408.10
Izumo1r
IZUMO1 receptor, JUNO
chr2_+_155593030 0.73 ENSMUST00000029140.12
ENSMUST00000132608.2
Procr
protein C receptor, endothelial
chrX_+_56098908 0.67 ENSMUST00000114751.9
ENSMUST00000088652.6
Htatsf1
HIV TAT specific factor 1
chr2_+_127183838 0.66 ENSMUST00000156747.2
Astl
astacin-like metalloendopeptidase (M12 family)
chr7_-_84339156 0.65 ENSMUST00000209117.2
ENSMUST00000207975.2
Zfand6
zinc finger, AN1-type domain 6
chr7_-_84339045 0.64 ENSMUST00000209165.2
Zfand6
zinc finger, AN1-type domain 6
chr17_-_35978438 0.64 ENSMUST00000043674.15
Vars2
valyl-tRNA synthetase 2, mitochondrial
chr5_+_31454939 0.60 ENSMUST00000201675.3
Gckr
glucokinase regulatory protein
chrX_+_85235370 0.60 ENSMUST00000026036.5
Nr0b1
nuclear receptor subfamily 0, group B, member 1
chr16_+_18245134 0.60 ENSMUST00000205679.3
Txnrd2
thioredoxin reductase 2
chr16_+_31482745 0.57 ENSMUST00000100001.10
ENSMUST00000064477.14
Dlg1
discs large MAGUK scaffold protein 1
chr14_+_101891416 0.57 ENSMUST00000002289.8
Uchl3
ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)
chr3_+_107008343 0.54 ENSMUST00000197470.5
Kcna2
potassium voltage-gated channel, shaker-related subfamily, member 2
chr2_-_142743438 0.53 ENSMUST00000230763.2
ENSMUST00000043589.8
Kif16b
kinesin family member 16B
chr15_+_100202642 0.52 ENSMUST00000067752.5
ENSMUST00000229588.2
Mettl7a1
methyltransferase like 7A1
chr4_-_126362372 0.51 ENSMUST00000097888.10
ENSMUST00000239399.2
Ago1
argonaute RISC catalytic subunit 1
chr2_-_180562718 0.47 ENSMUST00000037299.15
ENSMUST00000108876.9
Ythdf1
YTH N6-methyladenosine RNA binding protein 1
chr2_+_173952123 0.39 ENSMUST00000044415.16
Npepl1
aminopeptidase-like 1
chr2_+_130116357 0.38 ENSMUST00000136621.9
ENSMUST00000141872.2
Nop56
NOP56 ribonucleoprotein
chr3_+_89958940 0.37 ENSMUST00000159064.8
4933434E20Rik
RIKEN cDNA 4933434E20 gene
chr2_-_32674435 0.36 ENSMUST00000102813.2
Cfap157
cilia and flagella associated protein 157
chr11_-_109188947 0.35 ENSMUST00000020920.10
Rgs9
regulator of G-protein signaling 9
chr14_-_70855980 0.34 ENSMUST00000228001.2
Dmtn
dematin actin binding protein
chr10_-_23226034 0.34 ENSMUST00000219315.2
Eya4
EYA transcriptional coactivator and phosphatase 4
chr7_+_24310171 0.34 ENSMUST00000206422.2
Phldb3
pleckstrin homology like domain, family B, member 3
chr16_+_31482658 0.32 ENSMUST00000115201.8
Dlg1
discs large MAGUK scaffold protein 1
chr17_+_8559539 0.32 ENSMUST00000163887.2
Prr18
proline rich 18
chr3_+_65435825 0.30 ENSMUST00000047906.10
Tiparp
TCDD-inducible poly(ADP-ribose) polymerase
chr9_-_44920899 0.30 ENSMUST00000102832.3
Cd3e
CD3 antigen, epsilon polypeptide
chr7_-_80051455 0.29 ENSMUST00000120753.3
Furin
furin (paired basic amino acid cleaving enzyme)
chr2_-_172782089 0.29 ENSMUST00000009143.8
Bmp7
bone morphogenetic protein 7
chr1_+_90926443 0.28 ENSMUST00000189505.7
ENSMUST00000185531.7
ENSMUST00000068116.13
Lrrfip1
leucine rich repeat (in FLII) interacting protein 1
chr1_+_174329361 0.27 ENSMUST00000030039.13
Fmn2
formin 2
chr4_+_132495636 0.26 ENSMUST00000102561.11
Rpa2
replication protein A2
chr14_+_53061814 0.26 ENSMUST00000103648.4
Trav11d
T cell receptor alpha variable 11D
chr8_-_117809188 0.24 ENSMUST00000109093.9
ENSMUST00000098375.6
Pkd1l2
polycystic kidney disease 1 like 2
chr19_-_24257904 0.24 ENSMUST00000081333.11
Fxn
frataxin
chr7_-_142233270 0.24 ENSMUST00000162317.2
ENSMUST00000125933.2
ENSMUST00000105931.8
ENSMUST00000105930.8
ENSMUST00000105933.8
ENSMUST00000105932.2
ENSMUST00000000220.3
Ins2
insulin II
chr11_-_109188917 0.24 ENSMUST00000106704.3
Rgs9
regulator of G-protein signaling 9
chr7_+_127400016 0.22 ENSMUST00000106271.2
ENSMUST00000138432.2
Hsd3b7
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7
chr3_-_104869237 0.16 ENSMUST00000029429.6
Wnt2b
wingless-type MMTV integration site family, member 2B
chr14_+_58313964 0.15 ENSMUST00000166770.2
Fgf9
fibroblast growth factor 9
chr2_-_168607166 0.13 ENSMUST00000137536.2
Sall4
spalt like transcription factor 4
chr6_-_119940694 0.13 ENSMUST00000161512.3
Wnk1
WNK lysine deficient protein kinase 1
chr17_+_74645936 0.12 ENSMUST00000224711.2
ENSMUST00000024869.8
ENSMUST00000233611.2
Spast
spastin
chr8_-_32499513 0.11 ENSMUST00000208205.3
Nrg1
neuregulin 1
chr11_-_82761954 0.09 ENSMUST00000108173.10
ENSMUST00000071152.14
Rffl
ring finger and FYVE like domain containing protein
chr11_-_109188892 0.09 ENSMUST00000106706.8
Rgs9
regulator of G-protein signaling 9
chr2_+_29855572 0.08 ENSMUST00000113719.9
ENSMUST00000113717.8
ENSMUST00000113741.8
ENSMUST00000100225.9
ENSMUST00000095083.11
ENSMUST00000046257.14
Sptan1
spectrin alpha, non-erythrocytic 1
chr11_+_69826603 0.07 ENSMUST00000018698.12
Ybx2
Y box protein 2
chr9_+_118307918 0.07 ENSMUST00000150633.2
Eomes
eomesodermin
chr10_+_69369854 0.06 ENSMUST00000182557.8
Ank3
ankyrin 3, epithelial
chr15_-_57755753 0.05 ENSMUST00000022993.7
Derl1
Der1-like domain family, member 1
chr11_+_69826719 0.04 ENSMUST00000149194.8
Ybx2
Y box protein 2
chr13_+_104246259 0.03 ENSMUST00000160322.8
ENSMUST00000159574.2
Sgtb
small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta
chr18_+_40390013 0.02 ENSMUST00000096572.2
ENSMUST00000236889.2
Kctd16
potassium channel tetramerisation domain containing 16
chr3_-_141874955 0.00 ENSMUST00000098568.8
Bmpr1b
bone morphogenetic protein receptor, type 1B

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.2 GO:1903412 response to bile acid(GO:1903412) cellular response to bile acid(GO:1903413)
0.8 2.5 GO:0014805 smooth muscle adaptation(GO:0014805)
0.8 2.4 GO:0018160 peptidyl-pyrromethane cofactor linkage(GO:0018160)
0.8 4.0 GO:1904457 positive regulation of neuronal action potential(GO:1904457)
0.8 2.4 GO:1902462 transforming growth factor beta activation(GO:0036363) regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
0.7 2.7 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.5 1.5 GO:0034769 basement membrane disassembly(GO:0034769)
0.4 1.3 GO:1900369 negative regulation of RNA interference(GO:1900369)
0.4 2.7 GO:0035063 nuclear speck organization(GO:0035063)
0.4 1.3 GO:0048817 negative regulation of hair follicle maturation(GO:0048817)
0.4 3.7 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.4 2.1 GO:0050917 sensory perception of umami taste(GO:0050917)
0.3 2.0 GO:0032831 positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032831)
0.3 3.4 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.3 2.0 GO:0009750 response to fructose(GO:0009750)
0.3 2.1 GO:0070294 renal sodium ion absorption(GO:0070294)
0.2 1.7 GO:1902897 regulation of postsynaptic density protein 95 clustering(GO:1902897)
0.2 4.3 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.2 0.9 GO:1903760 regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903760)
0.2 2.6 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.2 3.1 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.2 1.7 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.2 1.3 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.2 2.0 GO:0051418 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.2 2.1 GO:0070474 positive regulation of uterine smooth muscle contraction(GO:0070474)
0.1 2.2 GO:0006517 protein deglycosylation(GO:0006517)
0.1 1.0 GO:0060023 soft palate development(GO:0060023)
0.1 2.3 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.1 0.7 GO:2000360 prevention of polyspermy(GO:0060468) negative regulation of binding of sperm to zona pellucida(GO:2000360)
0.1 1.2 GO:0001766 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.1 1.2 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
0.1 2.2 GO:0046415 urate metabolic process(GO:0046415)
0.1 0.6 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
0.1 5.5 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)
0.1 1.3 GO:1902474 positive regulation of protein localization to synapse(GO:1902474)
0.1 1.3 GO:0030223 neutrophil differentiation(GO:0030223)
0.1 0.3 GO:1900104 neural fold elevation formation(GO:0021502) hyaluranon cable assembly(GO:0036118) nephrogenic mesenchyme development(GO:0072076) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.1 1.1 GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.1 2.0 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.1 1.1 GO:0070245 positive regulation of thymocyte apoptotic process(GO:0070245)
0.1 0.5 GO:0021633 optic nerve structural organization(GO:0021633)
0.1 4.5 GO:0051497 negative regulation of stress fiber assembly(GO:0051497)
0.1 1.6 GO:0070995 NADPH oxidation(GO:0070995)
0.1 0.2 GO:1990535 neuron projection maintenance(GO:1990535)
0.1 0.2 GO:0060423 foregut regionalization(GO:0060423) lung field specification(GO:0060424) lung induction(GO:0060492)
0.1 1.3 GO:0032486 Rap protein signal transduction(GO:0032486)
0.1 0.3 GO:0090472 dibasic protein processing(GO:0090472)
0.1 0.6 GO:0035902 response to immobilization stress(GO:0035902)
0.1 0.3 GO:0070649 formin-nucleated actin cable assembly(GO:0070649)
0.1 0.5 GO:0035280 miRNA loading onto RISC involved in gene silencing by miRNA(GO:0035280)
0.1 0.2 GO:0019230 proprioception(GO:0019230)
0.1 0.3 GO:0035585 calcium-mediated signaling using extracellular calcium source(GO:0035585)
0.1 0.9 GO:0072697 protein localization to cell cortex(GO:0072697)
0.1 1.6 GO:0070233 negative regulation of T cell apoptotic process(GO:0070233)
0.0 1.3 GO:0072663 protein targeting to peroxisome(GO:0006625) peroxisomal transport(GO:0043574) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
0.0 1.5 GO:0030728 ovulation(GO:0030728)
0.0 1.8 GO:0014002 astrocyte development(GO:0014002)
0.0 0.9 GO:0030953 astral microtubule organization(GO:0030953)
0.0 1.1 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.3 GO:0002669 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.0 0.9 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.0 1.0 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 1.3 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.0 0.1 GO:0023016 signal transduction by trans-phosphorylation(GO:0023016)
0.0 1.0 GO:0006779 porphyrin-containing compound biosynthetic process(GO:0006779)
0.0 0.1 GO:0002302 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302) mesodermal to mesenchymal transition involved in gastrulation(GO:0060809)
0.0 0.3 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 0.1 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0 1.0 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 2.4 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.2 GO:0035754 B cell chemotaxis(GO:0035754)
0.0 0.4 GO:0007288 sperm axoneme assembly(GO:0007288)
0.0 0.5 GO:0045948 positive regulation of translational initiation(GO:0045948)
0.0 0.1 GO:0051013 microtubule severing(GO:0051013)
0.0 1.6 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.0 0.6 GO:0000305 response to oxygen radical(GO:0000305)
0.0 0.3 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.0 0.7 GO:0050819 negative regulation of coagulation(GO:0050819)
0.0 0.3 GO:0008210 estrogen metabolic process(GO:0008210)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 4.0 GO:0044316 cone cell pedicle(GO:0044316)
0.5 1.6 GO:1990031 pinceau fiber(GO:1990031)
0.4 1.2 GO:0036501 UFD1-NPL4 complex(GO:0036501)
0.2 0.9 GO:0008275 gamma-tubulin small complex(GO:0008275)
0.2 0.7 GO:0060473 cortical granule(GO:0060473)
0.2 3.1 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.2 3.2 GO:0046581 intercellular canaliculus(GO:0046581)
0.2 1.1 GO:0000931 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.2 3.4 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.1 2.3 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.1 0.9 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.1 1.3 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.1 1.7 GO:0016342 catenin complex(GO:0016342)
0.1 2.3 GO:0005859 muscle myosin complex(GO:0005859) myosin filament(GO:0032982)
0.1 1.2 GO:0001520 outer dense fiber(GO:0001520)
0.1 2.1 GO:0000242 pericentriolar material(GO:0000242)
0.1 1.0 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 1.2 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.3 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.0 1.3 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.5 GO:0070578 micro-ribonucleoprotein complex(GO:0035068) RISC-loading complex(GO:0070578)
0.0 0.4 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.0 0.6 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.7 GO:0005686 U2 snRNP(GO:0005686)
0.0 0.3 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 5.8 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 1.3 GO:0043034 costamere(GO:0043034)
0.0 2.1 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.2 GO:0005732 small nucleolar ribonucleoprotein complex(GO:0005732)
0.0 1.1 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.3 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.5 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.3 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.0 3.3 GO:0031225 anchored component of membrane(GO:0031225)
0.0 7.0 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 1.9 GO:0005901 caveola(GO:0005901)
0.0 0.1 GO:0032437 cuticular plate(GO:0032437)
0.0 0.7 GO:0001917 photoreceptor inner segment(GO:0001917)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.4 GO:0004418 hydroxymethylbilane synthase activity(GO:0004418)
0.6 2.5 GO:0034617 tetrahydrobiopterin binding(GO:0034617)
0.5 3.2 GO:0090554 phosphatidylcholine-translocating ATPase activity(GO:0090554)
0.4 2.1 GO:0042610 CD8 receptor binding(GO:0042610)
0.4 2.0 GO:0019976 interleukin-2 binding(GO:0019976)
0.4 5.8 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.2 3.1 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.2 0.7 GO:0070002 glutamic-type peptidase activity(GO:0070002)
0.2 2.0 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.2 4.8 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.2 1.5 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.1 1.3 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.1 4.3 GO:0005542 folic acid binding(GO:0005542)
0.1 1.3 GO:0003964 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.1 0.9 GO:0097016 L27 domain binding(GO:0097016)
0.1 2.3 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.1 1.7 GO:0045294 alpha-catenin binding(GO:0045294)
0.1 0.6 GO:0004832 valine-tRNA ligase activity(GO:0004832)
0.1 2.7 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 2.0 GO:0051011 microtubule minus-end binding(GO:0051011)
0.1 2.7 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.1 4.0 GO:0030552 cAMP binding(GO:0030552)
0.1 1.2 GO:0036435 K48-linked polyubiquitin binding(GO:0036435)
0.1 1.6 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.1 1.2 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.1 1.1 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.1 2.1 GO:0008527 taste receptor activity(GO:0008527)
0.1 2.4 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.1 1.4 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.1 1.0 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.1 0.9 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.1 1.9 GO:0008143 poly(A) binding(GO:0008143)
0.1 1.6 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.1 0.2 GO:0047016 cholest-5-ene-3-beta,7-alpha-diol 3-beta-dehydrogenase activity(GO:0047016)
0.1 2.7 GO:0071889 14-3-3 protein binding(GO:0071889)
0.1 3.4 GO:0004521 endoribonuclease activity(GO:0004521)
0.0 1.6 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.5 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 0.9 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.6 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.0 8.8 GO:0008236 serine-type peptidase activity(GO:0008236)
0.0 1.3 GO:0070412 R-SMAD binding(GO:0070412)
0.0 2.2 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 0.4 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 0.3 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.0 0.5 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 6.0 GO:0005088 Ras guanyl-nucleotide exchange factor activity(GO:0005088)
0.0 1.1 GO:0003785 actin monomer binding(GO:0003785)
0.0 1.1 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 0.3 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.2 GO:0016530 metallochaperone activity(GO:0016530)
0.0 0.1 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 1.0 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.6 GO:0000217 DNA secondary structure binding(GO:0000217)
0.0 1.3 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.8 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 1.8 GO:0005179 hormone activity(GO:0005179)
0.0 1.2 GO:0043621 protein self-association(GO:0043621)
0.0 0.3 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.1 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.1 5.9 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.1 3.1 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.1 2.5 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.1 3.3 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.1 3.6 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.1 1.7 PID NCADHERIN PATHWAY N-cadherin signaling events
0.1 2.3 PID RAS PATHWAY Regulation of Ras family activation
0.0 1.8 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.6 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 1.0 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.3 PID ALK2 PATHWAY ALK2 signaling events
0.0 4.1 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.7 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 1.3 PID AR PATHWAY Coregulation of Androgen receptor activity

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.4 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.2 1.6 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.1 1.5 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.1 3.1 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.1 2.0 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.1 2.5 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.1 2.4 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.1 4.0 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.1 2.1 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1 3.0 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 2.0 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.1 2.4 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 1.3 REACTOME ARMS MEDIATED ACTIVATION Genes involved in ARMS-mediated activation
0.1 0.9 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.1 3.3 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 2.0 REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0 1.6 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.0 0.6 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 1.8 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.3 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 3.2 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 2.3 REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)
0.0 0.2 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 3.4 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 1.0 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation