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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Vsx1_Uncx_Prrx2_Shox2_Noto

Z-value: 0.91

Motif logo

Transcription factors associated with Vsx1_Uncx_Prrx2_Shox2_Noto

Gene Symbol Gene ID Gene Info
ENSMUSG00000033080.10 Vsx1
ENSMUSG00000029546.13 Uncx
ENSMUSG00000039476.14 Prrx2
ENSMUSG00000027833.17 Shox2
ENSMUSG00000068302.9 Noto

Activity-expression correlation:

Activity profile of Vsx1_Uncx_Prrx2_Shox2_Noto motif

Sorted Z-values of Vsx1_Uncx_Prrx2_Shox2_Noto motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Vsx1_Uncx_Prrx2_Shox2_Noto

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr14_+_33662976 9.53 ENSMUST00000100720.2
growth differentiation factor 2
chr11_+_67090878 9.01 ENSMUST00000124516.8
ENSMUST00000018637.15
ENSMUST00000129018.8
myosin, heavy polypeptide 1, skeletal muscle, adult
chr10_-_107321938 6.69 ENSMUST00000000445.2
myogenic factor 5
chr4_+_98919183 5.83 ENSMUST00000030280.7
angiopoietin-like 3
chr11_+_114741948 5.70 ENSMUST00000133245.2
ENSMUST00000122967.3
G protein-coupled receptor, family C, group 5, member C
chr11_-_99213769 5.54 ENSMUST00000038004.3
keratin 25
chr9_-_71070506 5.48 ENSMUST00000074465.9
aquaporin 9
chr6_-_138056914 5.31 ENSMUST00000171804.4
solute carrier family 15, member 5
chrX_+_132751729 5.20 ENSMUST00000033602.9
tenomodulin
chr6_-_50631418 5.12 ENSMUST00000031853.8
neuropeptide VF precursor
chr11_+_114742331 4.99 ENSMUST00000177952.8
G protein-coupled receptor, family C, group 5, member C
chr4_-_35845204 4.94 ENSMUST00000164772.8
ENSMUST00000065173.9
leucine rich repeat and Ig domain containing 2
chr3_+_82915031 4.53 ENSMUST00000048486.13
ENSMUST00000194175.2
fibrinogen gamma chain
chr18_-_43610829 4.51 ENSMUST00000057110.11
eukaryotic translation initiation factor 3, subunit J2
chr7_+_114344920 4.00 ENSMUST00000136645.8
ENSMUST00000169913.8
INSC spindle orientation adaptor protein
chr13_-_113800172 3.97 ENSMUST00000054650.5
heat shock protein 3
chr1_-_163552693 3.76 ENSMUST00000159679.8
methyltransferase like 11B
chr10_-_107330580 3.67 ENSMUST00000044210.5
myogenic factor 6
chrX_+_149330371 3.63 ENSMUST00000066337.13
ENSMUST00000112715.2
aminolevulinic acid synthase 2, erythroid
chr7_+_51528788 3.42 ENSMUST00000107591.9
growth arrest specific 2
chr5_+_135135735 3.32 ENSMUST00000201977.4
ENSMUST00000005507.10
MLX interacting protein-like
chr6_-_41752111 3.24 ENSMUST00000214976.3
olfactory receptor 459
chr10_+_50770836 3.21 ENSMUST00000219436.2
single-minded family bHLH transcription factor 1
chr1_+_53100796 3.18 ENSMUST00000027269.7
ENSMUST00000191197.2
myostatin
chr2_-_168608949 3.06 ENSMUST00000075044.10
spalt like transcription factor 4
chrM_+_10167 3.01 ENSMUST00000082414.1
mitochondrially encoded NADH dehydrogenase 4
chr3_+_55689921 3.00 ENSMUST00000075422.6
mab-21-like 1
chr11_-_100653754 2.96 ENSMUST00000107360.3
ENSMUST00000055083.4
hypocretin
chr1_-_72323464 2.90 ENSMUST00000027381.13
peroxisomal trans-2-enoyl-CoA reductase
chr10_-_76276278 2.80 ENSMUST00000235907.2
novel protein
chr6_-_138404076 2.72 ENSMUST00000203435.3
LIM domain only 3
chr2_-_34990689 2.72 ENSMUST00000226631.2
ENSMUST00000045776.5
ENSMUST00000226972.2
expressed sequence AI182371
chr1_-_72323407 2.70 ENSMUST00000097698.5
peroxisomal trans-2-enoyl-CoA reductase
chr7_-_4909515 2.67 ENSMUST00000210663.2
predicted gene, 36210
chr2_+_124978612 2.67 ENSMUST00000099452.3
ENSMUST00000238377.2
cortexin 2
chr2_+_124978518 2.66 ENSMUST00000238754.2
cortexin 2
chr14_-_64654397 2.64 ENSMUST00000210428.2
methionine sulfoxide reductase A
chr11_+_67689094 2.62 ENSMUST00000168612.8
dehydrogenase/reductase (SDR family) member 7C
chr9_+_118307250 2.61 ENSMUST00000111763.8
eomesodermin
chr19_-_7943365 2.57 ENSMUST00000182102.8
ENSMUST00000075619.5
solute carrier family 22, member 27
chr17_-_84154173 2.53 ENSMUST00000000687.9
3-hydroxyanthranilate 3,4-dioxygenase
chr11_-_99441687 2.52 ENSMUST00000092700.5
keratin associated protein 3-3
chr3_+_59989282 2.52 ENSMUST00000029326.6
succinate receptor 1
chr16_+_22737227 2.48 ENSMUST00000231880.2
fetuin beta
chr15_-_34356567 2.45 ENSMUST00000179647.2
RIKEN cDNA 9430069I07 gene
chr5_+_104350475 2.44 ENSMUST00000066708.7
dentin matrix protein 1
chr6_-_30936013 2.43 ENSMUST00000101589.5
Kruppel-like factor 14
chr14_-_64654592 2.41 ENSMUST00000210363.2
methionine sulfoxide reductase A
chr16_+_22737128 2.36 ENSMUST00000170805.9
fetuin beta
chr17_-_84154196 2.35 ENSMUST00000234214.2
3-hydroxyanthranilate 3,4-dioxygenase
chr5_+_88603847 2.34 ENSMUST00000198265.5
ENSMUST00000031226.9
ameloblastin
chr16_+_22737050 2.34 ENSMUST00000231768.2
fetuin beta
chr2_+_67935015 2.34 ENSMUST00000042456.4
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1
chr15_+_92495007 2.33 ENSMUST00000035399.10
PDZ domain containing RING finger 4
chr9_+_118307412 2.25 ENSMUST00000035020.15
eomesodermin
chr2_+_9887427 2.21 ENSMUST00000114919.2
RIKEN cDNA 4930412O13 gene
chr7_-_115423934 2.20 ENSMUST00000169129.8
SRY (sex determining region Y)-box 6
chr4_+_109835224 2.17 ENSMUST00000061187.4
doublesex and mab-3 related transcription factor like family A2
chr9_+_72714156 2.16 ENSMUST00000055535.9
protogenin
chr11_+_67061908 2.13 ENSMUST00000018641.8
myosin, heavy polypeptide 2, skeletal muscle, adult
chr7_-_115459082 2.12 ENSMUST00000206123.2
SRY (sex determining region Y)-box 6
chr7_-_101765915 2.11 ENSMUST00000084830.2
cholinergic receptor, nicotinic, alpha polypeptide 10
chr9_+_44309727 2.10 ENSMUST00000213268.2
solute carrier family 37 (glucose-6-phosphate transporter), member 4
chr7_+_49559859 2.05 ENSMUST00000056442.12
solute carrier family 6 (neurotransmitter transporter, glycine), member 5
chr8_-_3674993 2.05 ENSMUST00000142431.8
Purkinje cell protein 2 (L7)
chr7_-_44752508 2.05 ENSMUST00000209830.2
Fc fragment of IgG receptor and transporter
chr11_+_67061837 2.02 ENSMUST00000170159.8
myosin, heavy polypeptide 2, skeletal muscle, adult
chr7_-_84339156 1.99 ENSMUST00000209117.2
ENSMUST00000207975.2
zinc finger, AN1-type domain 6
chr14_-_118289557 1.97 ENSMUST00000022725.4
dopachrome tautomerase
chr11_-_99265721 1.92 ENSMUST00000006963.3
keratin 28
chr11_-_99494134 1.91 ENSMUST00000072306.4
predicted gene 11938
chr11_-_59466995 1.85 ENSMUST00000215339.2
ENSMUST00000214351.2
olfactory receptor 222
chr11_-_43792013 1.85 ENSMUST00000067258.9
ENSMUST00000139906.2
adrenergic receptor, alpha 1b
chr8_+_46080746 1.82 ENSMUST00000145458.9
ENSMUST00000134321.8
sorbin and SH3 domain containing 2
chr7_-_49286594 1.81 ENSMUST00000032717.7
developing brain homeobox 1
chr6_+_63232955 1.81 ENSMUST00000095852.5
glutamate receptor, ionotropic, delta 2
chr2_-_168607166 1.80 ENSMUST00000137536.2
spalt like transcription factor 4
chrX_-_142716085 1.76 ENSMUST00000087313.10
doublecortin
chrM_+_9870 1.76 ENSMUST00000084013.1
mitochondrially encoded NADH dehydrogenase 4L
chrX_+_99019176 1.75 ENSMUST00000113781.8
ENSMUST00000113783.8
ENSMUST00000113779.8
ENSMUST00000113776.8
ENSMUST00000113775.8
ENSMUST00000113780.8
ENSMUST00000113778.8
ENSMUST00000113777.8
ENSMUST00000071453.3
ectodysplasin-A
chr9_+_24194729 1.74 ENSMUST00000154644.2
neuropeptide S receptor 1
chr2_-_168609110 1.72 ENSMUST00000029061.12
ENSMUST00000103074.2
spalt like transcription factor 4
chr8_-_49008305 1.72 ENSMUST00000110346.9
ENSMUST00000211976.2
teneurin transmembrane protein 3
chr16_+_42727926 1.71 ENSMUST00000151244.8
ENSMUST00000114694.9
zinc finger and BTB domain containing 20
chr11_+_70410009 1.71 ENSMUST00000057685.3
glycolipid transfer protein domain containing 2
chr13_+_8252957 1.70 ENSMUST00000123187.2
adenosine deaminase, RNA-specific, B2
chr11_+_70410445 1.70 ENSMUST00000179000.2
glycolipid transfer protein domain containing 2
chr12_-_11258973 1.70 ENSMUST00000049877.3
mesogenin 1
chr1_-_9369463 1.69 ENSMUST00000140295.8
syntrophin, gamma 1
chr7_-_12829100 1.69 ENSMUST00000209822.3
ENSMUST00000235753.2
vomeronasal 1 receptor 85
chr13_+_22563988 1.68 ENSMUST00000227685.2
ENSMUST00000227689.2
ENSMUST00000227846.2
vomeronasal 1 receptor 199
chr14_-_109151590 1.67 ENSMUST00000100322.4
SLIT and NTRK-like family, member 1
chr7_-_44753168 1.66 ENSMUST00000211085.2
ENSMUST00000210642.2
ENSMUST00000003512.9
Fc fragment of IgG receptor and transporter
chr1_-_9369045 1.65 ENSMUST00000191683.6
syntrophin, gamma 1
chr8_+_84262409 1.64 ENSMUST00000214156.2
ENSMUST00000209408.4
olfactory receptor 370
chr2_-_27365633 1.64 ENSMUST00000138693.8
ENSMUST00000113941.9
ENSMUST00000077737.13
bromodomain containing 3
chr19_+_39980868 1.63 ENSMUST00000049178.3
cytochrome P450, family 2. subfamily c, polypeptide 37
chr5_+_108842294 1.63 ENSMUST00000013633.12
fibroblast growth factor receptor-like 1
chr13_-_23041731 1.63 ENSMUST00000228645.2
vomeronasal 1 receptor 211
chr13_+_8252895 1.60 ENSMUST00000064473.13
adenosine deaminase, RNA-specific, B2
chrX_+_149372903 1.59 ENSMUST00000080884.11
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr10_+_85763545 1.58 ENSMUST00000170396.3
achaete-scute family bHLH transcription factor 4
chr1_+_132155922 1.58 ENSMUST00000191418.2
LEM domain containing 1
chr4_-_43823866 1.57 ENSMUST00000215406.2
ENSMUST00000079234.6
ENSMUST00000214843.2
olfactory receptor 156
chr1_-_9368721 1.53 ENSMUST00000132064.8
syntrophin, gamma 1
chr4_-_97666279 1.52 ENSMUST00000146447.8
RIKEN cDNA E130114P18 gene
chr18_-_39000056 1.52 ENSMUST00000236630.2
ENSMUST00000237356.2
fibroblast growth factor 1
chr13_+_75855695 1.51 ENSMUST00000222194.2
ENSMUST00000223535.2
ENSMUST00000222853.2
elongation factor for RNA polymerase II 2
chr8_+_22996233 1.50 ENSMUST00000210854.2
solute carrier family 20, member 2
chr11_-_99228756 1.50 ENSMUST00000100482.3
keratin 26
chr19_-_13828056 1.50 ENSMUST00000208493.3
olfactory receptor 1501
chr7_+_126550009 1.49 ENSMUST00000106332.3
seizure related 6 homolog like 2
chr15_-_34495329 1.48 ENSMUST00000022946.6
reactive intermediate imine deaminase A homolog
chr13_+_22454692 1.48 ENSMUST00000228711.2
vomeronasal 1 receptor 195
chr2_+_61634797 1.47 ENSMUST00000048934.15
T-box brain transcription factor 1
chr13_+_27241551 1.47 ENSMUST00000110369.10
ENSMUST00000224228.2
ENSMUST00000018061.7
prolactin
chr1_+_104696235 1.46 ENSMUST00000062528.9
cadherin 20
chr15_+_55171138 1.46 ENSMUST00000023053.12
ENSMUST00000110217.10
collagen, type XIV, alpha 1
chr15_-_101710781 1.45 ENSMUST00000063292.8
keratin 73
chr19_-_13827773 1.45 ENSMUST00000215350.2
olfactory receptor 1501
chr1_+_88234454 1.44 ENSMUST00000040210.14
transient receptor potential cation channel, subfamily M, member 8
chr11_-_99979052 1.43 ENSMUST00000107419.2
keratin 32
chr3_-_154034271 1.43 ENSMUST00000204403.2
LIM homeobox protein 8
chr14_+_54436247 1.42 ENSMUST00000103720.2
T cell receptor alpha joining 21
chrX_-_142716200 1.41 ENSMUST00000112851.8
ENSMUST00000112856.3
ENSMUST00000033642.10
doublecortin
chr18_-_81029986 1.40 ENSMUST00000057950.9
spalt like transcription factor 3
chr9_-_103099262 1.39 ENSMUST00000170904.2
transferrin
chr8_+_121842902 1.39 ENSMUST00000054691.8
forkhead box C2
chr3_+_57332735 1.39 ENSMUST00000029377.8
transmembrane 4 superfamily member 4
chr8_-_3675274 1.37 ENSMUST00000004749.7
Purkinje cell protein 2 (L7)
chr4_+_114914880 1.36 ENSMUST00000161601.8
T cell acute lymphocytic leukemia 1
chr16_-_92196954 1.36 ENSMUST00000023672.10
regulator of calcineurin 1
chr13_+_111391544 1.36 ENSMUST00000054716.4
actin, beta-like 2
chr13_+_23991010 1.34 ENSMUST00000006786.11
ENSMUST00000099697.3
solute carrier family 17 (sodium phosphate), member 2
chr12_+_30934320 1.33 ENSMUST00000067087.7
ALK and LTK ligand 2
chr9_-_44714263 1.32 ENSMUST00000044694.8
tetratricopeptide repeat domain 36
chr7_+_126549859 1.32 ENSMUST00000106333.8
seizure related 6 homolog like 2
chr8_-_69541852 1.31 ENSMUST00000037478.13
ENSMUST00000148856.2
solute carrier family 18 (vesicular monoamine), member 1
chr8_-_32408864 1.29 ENSMUST00000073884.7
ENSMUST00000238812.2
neuregulin 1
chr8_+_46080840 1.28 ENSMUST00000135336.9
sorbin and SH3 domain containing 2
chr13_+_83723743 1.28 ENSMUST00000198217.5
ENSMUST00000199210.5
myocyte enhancer factor 2C
chr5_+_139529643 1.28 ENSMUST00000174792.2
UNC homeobox
chr7_-_101765970 1.27 ENSMUST00000211408.2
cholinergic receptor, nicotinic, alpha polypeptide 10
chr9_+_38755745 1.26 ENSMUST00000217350.2
olfactory receptor 924
chr12_+_38830812 1.25 ENSMUST00000160856.8
ets variant 1
chr8_-_3675024 1.24 ENSMUST00000133459.8
Purkinje cell protein 2 (L7)
chr6_+_37847721 1.23 ENSMUST00000031859.14
ENSMUST00000120428.8
tripartite motif-containing 24
chr9_+_37829844 1.23 ENSMUST00000212878.2
ENSMUST00000086061.4
olfactory receptor 878
chr7_+_126549692 1.22 ENSMUST00000106335.8
ENSMUST00000146017.3
seizure related 6 homolog like 2
chr5_+_115373895 1.22 ENSMUST00000081497.13
processing of precursor 5, ribonuclease P/MRP family (S. cerevisiae)
chr15_+_21111428 1.21 ENSMUST00000075132.8
cadherin 12
chr8_-_32408786 1.21 ENSMUST00000239000.2
neuregulin 1
chr3_-_92441809 1.21 ENSMUST00000193521.2
RIKEN cDNA 2310046K23 gene
chr9_-_37580478 1.20 ENSMUST00000011262.4
pannexin 3
chr2_+_87725306 1.19 ENSMUST00000217436.2
olfactory receptor 1153
chr1_-_189902868 1.18 ENSMUST00000177288.4
ENSMUST00000175916.8
prospero homeobox 1
chr19_-_45224251 1.17 ENSMUST00000099401.6
ladybird homeobox 1
chr2_+_69727563 1.16 ENSMUST00000055758.16
ENSMUST00000112251.9
ubiquitin protein ligase E3 component n-recognin 3
chr18_+_23548192 1.15 ENSMUST00000222515.2
dystrobrevin alpha
chr11_-_107228382 1.15 ENSMUST00000040380.13
phosphatidylinositol transfer protein, cytoplasmic 1
chr3_+_76500857 1.14 ENSMUST00000162471.2
follistatin-like 5
chr2_-_57942844 1.14 ENSMUST00000090940.6
ermin, ERM-like protein
chr7_-_84339045 1.13 ENSMUST00000209165.2
zinc finger, AN1-type domain 6
chr18_-_81029751 1.12 ENSMUST00000238808.2
spalt like transcription factor 3
chr15_+_39522905 1.11 ENSMUST00000226410.2
regulating synaptic membrane exocytosis 2
chr15_-_11038077 1.11 ENSMUST00000058007.7
relaxin family peptide receptor 3
chr19_-_11838430 1.11 ENSMUST00000214796.2
olfactory receptor 1418
chr13_+_83723255 1.10 ENSMUST00000199167.5
ENSMUST00000195904.5
myocyte enhancer factor 2C
chr2_-_63014514 1.08 ENSMUST00000112452.2
potassium voltage-gated channel, subfamily H (eag-related), member 7
chr13_-_53627110 1.07 ENSMUST00000021922.10
msh homeobox 2
chr2_+_22959452 1.07 ENSMUST00000155602.4
acyl-Coenzyme A binding domain containing 5
chr14_-_48902555 1.07 ENSMUST00000118578.9
orthodenticle homeobox 2
chr2_-_34951443 1.06 ENSMUST00000028233.7
hemolytic complement
chr1_-_150341911 1.05 ENSMUST00000162367.8
ENSMUST00000161611.8
ENSMUST00000161320.8
ENSMUST00000159035.2
proteoglycan 4 (megakaryocyte stimulating factor, articular superficial zone protein)
chr16_+_43574389 1.03 ENSMUST00000229953.2
dopamine receptor D3
chr11_+_116734104 1.03 ENSMUST00000106370.10
methyltransferase like 23
chr13_-_23302396 1.02 ENSMUST00000227110.2
vomeronasal 1 receptor 217
chr4_+_34893772 1.02 ENSMUST00000029975.10
ENSMUST00000135871.8
ENSMUST00000108130.2
glycoprotein hormones, alpha subunit
chr2_-_86857424 1.00 ENSMUST00000214857.2
ENSMUST00000215972.2
olfactory receptor 1104
chr15_+_101371353 1.00 ENSMUST00000088049.5
keratin 86
chr1_-_14380418 1.00 ENSMUST00000027066.13
ENSMUST00000168081.9
EYA transcriptional coactivator and phosphatase 1
chr2_+_71359000 1.00 ENSMUST00000126400.2
distal-less homeobox 1
chr13_+_23214588 1.00 ENSMUST00000227652.2
ENSMUST00000227236.2
vomeronasal 1 receptor 214
chr7_-_108774367 0.99 ENSMUST00000207178.2
LIM domain only 1
chr10_+_127734384 0.99 ENSMUST00000047134.8
4short chain dehydrogenase/reductase family 9C, member 7
chr14_+_111912529 0.99 ENSMUST00000042767.9
SLIT and NTRK-like family, member 5
chrX_+_151909893 0.98 ENSMUST00000163801.2
forkhead box R2
chr9_-_76120939 0.97 ENSMUST00000074880.6
GDNF family receptor alpha like
chr7_+_43418404 0.97 ENSMUST00000014063.6
kallikrein related-peptidase 12
chr18_-_3281089 0.97 ENSMUST00000139537.2
ENSMUST00000124747.8
cAMP responsive element modulator
chr17_+_38104420 0.96 ENSMUST00000216051.3
olfactory receptor 123
chr1_-_92446383 0.96 ENSMUST00000062353.12
olfactory receptor 1414
chr13_-_23302027 0.95 ENSMUST00000228656.2
vomeronasal 1 receptor 217
chr12_+_108145802 0.95 ENSMUST00000221167.2
cyclin K
chr17_+_93506590 0.94 ENSMUST00000064775.8
adenylate cyclase activating polypeptide 1
chr7_-_45480200 0.92 ENSMUST00000107723.9
ENSMUST00000131384.3
glutamate-rich WD repeat containing 1
chr3_-_92031247 0.92 ENSMUST00000070284.4
proline rich 9
chr1_-_14380327 0.92 ENSMUST00000080664.14
EYA transcriptional coactivator and phosphatase 1
chr2_+_69727599 0.91 ENSMUST00000131553.2
ubiquitin protein ligase E3 component n-recognin 3
chr13_+_22474090 0.91 ENSMUST00000228382.2
ENSMUST00000228557.2
ENSMUST00000226245.2
ENSMUST00000227516.2
vomeronasal 1 receptor 196

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 5.6 GO:0033306 phytol metabolic process(GO:0033306) fatty alcohol metabolic process(GO:1903173)
1.4 5.5 GO:0015855 nucleobase transport(GO:0015851) pyrimidine nucleobase transport(GO:0015855)
1.3 10.4 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
1.2 4.9 GO:0002302 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302)
1.1 3.2 GO:0014732 skeletal muscle atrophy(GO:0014732)
1.0 5.8 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.9 1.7 GO:2000293 regulation of defecation(GO:2000292) negative regulation of defecation(GO:2000293)
0.8 3.3 GO:0090324 negative regulation of oxidative phosphorylation(GO:0090324)
0.7 2.0 GO:0006583 melanin biosynthetic process from tyrosine(GO:0006583)
0.6 3.1 GO:0070173 regulation of enamel mineralization(GO:0070173)
0.6 1.8 GO:0001982 baroreceptor response to decreased systemic arterial blood pressure(GO:0001982)
0.5 4.9 GO:0046874 quinolinate metabolic process(GO:0046874)
0.5 2.1 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.5 2.1 GO:0036233 glycine import(GO:0036233)
0.5 5.1 GO:0032277 negative regulation of gonadotropin secretion(GO:0032277)
0.5 1.4 GO:0033189 response to vitamin A(GO:0033189)
0.5 1.4 GO:0060217 hemangioblast cell differentiation(GO:0060217)
0.4 1.3 GO:0070376 regulation of ERK5 cascade(GO:0070376)
0.4 4.8 GO:2000741 positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.4 1.7 GO:0061152 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.4 0.9 GO:1903860 negative regulation of dendrite extension(GO:1903860)
0.4 1.7 GO:0050973 detection of mechanical stimulus involved in equilibrioception(GO:0050973)
0.4 1.2 GO:0046619 optic placode formation involved in camera-type eye formation(GO:0046619)
0.4 3.0 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.4 1.1 GO:2001055 positive regulation of mesenchymal cell apoptotic process(GO:2001055)
0.4 1.8 GO:0071651 positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651)
0.3 1.4 GO:0003275 apoptotic process involved in outflow tract morphogenesis(GO:0003275) regulation of apoptotic process involved in outflow tract morphogenesis(GO:1902256)
0.3 1.0 GO:0032416 negative regulation of sodium:proton antiporter activity(GO:0032416)
0.3 1.0 GO:0021893 cerebral cortex GABAergic interneuron fate commitment(GO:0021893) positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868) positive regulation of amacrine cell differentiation(GO:1902871)
0.3 4.5 GO:0072378 blood coagulation, fibrin clot formation(GO:0072378)
0.3 3.2 GO:0021842 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.3 2.0 GO:1901509 regulation of endothelial tube morphogenesis(GO:1901509)
0.3 0.9 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.3 3.4 GO:0016056 rhodopsin mediated signaling pathway(GO:0016056)
0.3 2.3 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.3 14.7 GO:0001937 negative regulation of endothelial cell proliferation(GO:0001937)
0.3 6.6 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.2 2.7 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.2 1.5 GO:0001661 conditioned taste aversion(GO:0001661) amygdala development(GO:0021764)
0.2 2.4 GO:0090520 sphingolipid mediated signaling pathway(GO:0090520)
0.2 2.1 GO:0035166 post-embryonic hemopoiesis(GO:0035166)
0.2 4.1 GO:0001778 plasma membrane repair(GO:0001778)
0.2 1.3 GO:0051365 cellular response to potassium ion starvation(GO:0051365)
0.2 2.0 GO:0051611 regulation of serotonin uptake(GO:0051611)
0.2 3.4 GO:0048664 neuron fate determination(GO:0048664)
0.2 1.1 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
0.2 1.5 GO:0007262 STAT protein import into nucleus(GO:0007262)
0.2 0.6 GO:0021934 hindbrain tangential cell migration(GO:0021934)
0.2 1.6 GO:0044828 negative regulation by host of viral genome replication(GO:0044828)
0.2 2.4 GO:0003172 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.2 2.0 GO:0030242 pexophagy(GO:0030242)
0.2 3.2 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.2 1.4 GO:0070447 positive regulation of oligodendrocyte progenitor proliferation(GO:0070447)
0.2 2.6 GO:0015747 urate transport(GO:0015747)
0.2 1.5 GO:0042795 snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.2 0.5 GO:2000328 regulation of T-helper 17 cell lineage commitment(GO:2000328)
0.2 1.6 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.2 3.0 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.2 1.1 GO:0051697 protein delipidation(GO:0051697)
0.2 1.3 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.2 3.4 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.2 1.8 GO:0021521 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.1 1.0 GO:0045409 negative regulation of interleukin-6 biosynthetic process(GO:0045409)
0.1 2.5 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.1 1.4 GO:0050955 thermoception(GO:0050955)
0.1 0.7 GO:0010587 miRNA catabolic process(GO:0010587)
0.1 1.3 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.1 1.0 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.1 3.7 GO:0050910 detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.1 1.2 GO:0009249 protein lipoylation(GO:0009249)
0.1 4.4 GO:0045109 intermediate filament organization(GO:0045109)
0.1 0.4 GO:1903538 meiotic cell cycle process involved in oocyte maturation(GO:1903537) regulation of meiotic cell cycle process involved in oocyte maturation(GO:1903538)
0.1 0.5 GO:0042536 negative regulation of tumor necrosis factor biosynthetic process(GO:0042536)
0.1 0.8 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.1 1.2 GO:0046884 follicle-stimulating hormone secretion(GO:0046884)
0.1 0.4 GO:0002396 MHC protein complex assembly(GO:0002396) peptide antigen assembly with MHC protein complex(GO:0002501)
0.1 7.0 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
0.1 0.6 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.1 0.4 GO:0018065 protein-cofactor linkage(GO:0018065)
0.1 0.5 GO:1902811 tongue muscle cell differentiation(GO:0035981) positive regulation of skeletal muscle fiber differentiation(GO:1902811) regulation of tongue muscle cell differentiation(GO:2001035) positive regulation of tongue muscle cell differentiation(GO:2001037)
0.1 0.3 GO:0003166 thigmotaxis(GO:0001966) bundle of His development(GO:0003166)
0.1 1.7 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.1 4.0 GO:0090036 regulation of protein kinase C signaling(GO:0090036)
0.1 3.1 GO:0072662 protein targeting to peroxisome(GO:0006625) peroxisomal transport(GO:0043574) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
0.1 0.8 GO:0051964 negative regulation of synapse assembly(GO:0051964)
0.1 0.3 GO:0030221 basophil differentiation(GO:0030221)
0.1 0.6 GO:0099527 postsynapse to nucleus signaling pathway(GO:0099527)
0.1 1.8 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.1 3.4 GO:0006783 heme biosynthetic process(GO:0006783)
0.1 13.2 GO:0019236 response to pheromone(GO:0019236)
0.1 0.7 GO:0000270 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.1 0.8 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.1 1.7 GO:0097264 self proteolysis(GO:0097264)
0.1 1.1 GO:0061669 spontaneous neurotransmitter secretion(GO:0061669) positive regulation of inhibitory postsynaptic potential(GO:0097151) spontaneous synaptic transmission(GO:0098814)
0.1 5.5 GO:0061049 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.1 3.8 GO:0031365 N-terminal protein amino acid modification(GO:0031365)
0.1 0.3 GO:0023016 signal transduction by trans-phosphorylation(GO:0023016)
0.1 1.7 GO:0007379 segment specification(GO:0007379)
0.1 0.3 GO:0098582 innate vocalization behavior(GO:0098582)
0.1 1.7 GO:0060539 diaphragm development(GO:0060539)
0.1 0.7 GO:0019243 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.1 0.6 GO:0005513 detection of calcium ion(GO:0005513)
0.1 0.8 GO:0018298 protein-chromophore linkage(GO:0018298)
0.1 0.2 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.1 0.3 GO:0051684 maintenance of Golgi location(GO:0051684)
0.1 0.3 GO:0051799 negative regulation of hair follicle development(GO:0051799)
0.1 0.2 GO:0052422 modulation by symbiont of host molecular function(GO:0052055) modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422)
0.1 1.4 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.1 0.5 GO:0009642 response to light intensity(GO:0009642)
0.1 0.1 GO:0060355 positive regulation of cell adhesion molecule production(GO:0060355)
0.1 7.3 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.1 0.3 GO:0035553 oxidative single-stranded RNA demethylation(GO:0035553)
0.1 2.5 GO:0045879 negative regulation of smoothened signaling pathway(GO:0045879)
0.1 1.2 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.1 1.4 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.1 9.0 GO:0007601 visual perception(GO:0007601)
0.1 2.7 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.1 1.5 GO:0010880 regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum(GO:0010880)
0.1 0.7 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1 0.6 GO:0051177 meiotic sister chromatid cohesion(GO:0051177)
0.0 1.6 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.0 0.6 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.1 GO:0060468 prevention of polyspermy(GO:0060468)
0.0 0.9 GO:0006337 nucleosome disassembly(GO:0006337)
0.0 0.4 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.0 0.7 GO:0045199 maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.0 0.4 GO:0030916 otic vesicle formation(GO:0030916)
0.0 0.2 GO:0048165 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.0 0.2 GO:0061743 motor learning(GO:0061743)
0.0 0.4 GO:0051798 positive regulation of hair follicle development(GO:0051798)
0.0 1.4 GO:0000132 establishment of mitotic spindle orientation(GO:0000132)
0.0 0.3 GO:0090521 glomerular visceral epithelial cell migration(GO:0090521)
0.0 0.3 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
0.0 0.1 GO:0000966 RNA 5'-end processing(GO:0000966)
0.0 0.6 GO:0010944 negative regulation of transcription by competitive promoter binding(GO:0010944)
0.0 0.2 GO:0035660 MyD88-dependent toll-like receptor 4 signaling pathway(GO:0035660)
0.0 0.1 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.0 0.6 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.0 0.2 GO:0002729 positive regulation of natural killer cell cytokine production(GO:0002729)
0.0 37.0 GO:0007608 sensory perception of smell(GO:0007608)
0.0 0.6 GO:0032516 positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.0 0.2 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.0 0.2 GO:1903817 negative regulation of delayed rectifier potassium channel activity(GO:1902260) negative regulation of voltage-gated potassium channel activity(GO:1903817)
0.0 0.4 GO:0045332 phospholipid translocation(GO:0045332)
0.0 1.8 GO:0006687 glycosphingolipid metabolic process(GO:0006687)
0.0 0.7 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 0.5 GO:0030049 muscle filament sliding(GO:0030049)
0.0 0.2 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.4 GO:0060484 lung-associated mesenchyme development(GO:0060484)
0.0 1.5 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.0 5.0 GO:0007568 aging(GO:0007568)
0.0 0.8 GO:1903963 arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.0 0.6 GO:0035115 embryonic forelimb morphogenesis(GO:0035115)
0.0 0.2 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.0 0.4 GO:0042474 middle ear morphogenesis(GO:0042474)
0.0 0.0 GO:0010288 response to lead ion(GO:0010288)
0.0 0.9 GO:1901099 negative regulation of signal transduction in absence of ligand(GO:1901099) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.0 0.8 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.1 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
0.0 0.0 GO:0021524 visceral motor neuron differentiation(GO:0021524)
0.0 0.8 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 3.3 GO:0007606 sensory perception of chemical stimulus(GO:0007606)
0.0 0.2 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.0 0.6 GO:0030502 negative regulation of bone mineralization(GO:0030502)
0.0 0.1 GO:0090273 regulation of somatostatin secretion(GO:0090273)
0.0 0.2 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.0 0.3 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.0 3.0 GO:0007050 cell cycle arrest(GO:0007050)
0.0 1.4 GO:0035725 sodium ion transmembrane transport(GO:0035725)
0.0 0.1 GO:0001712 ectodermal cell fate commitment(GO:0001712)
0.0 0.1 GO:0033152 immunoglobulin V(D)J recombination(GO:0033152)
0.0 0.3 GO:0016048 detection of temperature stimulus(GO:0016048)
0.0 0.3 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.0 0.4 GO:0035066 positive regulation of histone acetylation(GO:0035066) positive regulation of peptidyl-lysine acetylation(GO:2000758)
0.0 0.1 GO:0009826 unidimensional cell growth(GO:0009826)
0.0 0.3 GO:1903859 regulation of dendrite extension(GO:1903859)
0.0 0.7 GO:0042982 amyloid precursor protein metabolic process(GO:0042982)
0.0 0.8 GO:0033120 positive regulation of RNA splicing(GO:0033120)
0.0 0.3 GO:0006817 phosphate ion transport(GO:0006817)
0.0 0.4 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.0 4.8 GO:0015833 peptide transport(GO:0015833)
0.0 0.7 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.0 4.0 GO:0006936 muscle contraction(GO:0006936)
0.0 0.0 GO:2000318 positive regulation of T-helper 17 type immune response(GO:2000318)
0.0 0.2 GO:0006744 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744)
0.0 0.3 GO:0031069 hair follicle morphogenesis(GO:0031069)
0.0 0.2 GO:0010592 positive regulation of lamellipodium assembly(GO:0010592)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.6 GO:0014801 longitudinal sarcoplasmic reticulum(GO:0014801)
0.5 1.6 GO:0002944 cyclin K-CDK12 complex(GO:0002944) cyclin K-CDK13 complex(GO:0002945)
0.5 1.6 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.5 4.1 GO:0005826 actomyosin contractile ring(GO:0005826)
0.5 4.5 GO:0005577 fibrinogen complex(GO:0005577)
0.5 1.4 GO:0033193 Lsd1/2 complex(GO:0033193)
0.4 9.3 GO:0032982 myosin filament(GO:0032982)
0.2 4.5 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.2 1.1 GO:0035841 new growing cell tip(GO:0035841)
0.2 1.0 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.2 3.4 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.2 1.2 GO:0005726 perichromatin fibrils(GO:0005726)
0.1 1.1 GO:0033269 internode region of axon(GO:0033269)
0.1 0.5 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.1 1.4 GO:0001674 female germ cell nucleus(GO:0001674)
0.1 1.4 GO:0097433 dense body(GO:0097433)
0.1 16.9 GO:0005882 intermediate filament(GO:0005882)
0.1 1.1 GO:0005579 membrane attack complex(GO:0005579)
0.1 2.1 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.1 0.4 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.1 5.6 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.1 2.0 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.1 2.6 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 1.5 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.1 GO:0043512 inhibin A complex(GO:0043512)
0.0 0.3 GO:0070695 FHF complex(GO:0070695)
0.0 0.4 GO:0042824 MHC class I peptide loading complex(GO:0042824)
0.0 0.3 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 0.2 GO:0098574 cytoplasmic side of lysosomal membrane(GO:0098574)
0.0 0.6 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.5 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 1.7 GO:0032809 neuronal cell body membrane(GO:0032809)
0.0 1.1 GO:0060077 inhibitory synapse(GO:0060077)
0.0 3.8 GO:0032587 ruffle membrane(GO:0032587)
0.0 3.5 GO:0044291 cell-cell contact zone(GO:0044291)
0.0 2.0 GO:0098878 ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)
0.0 0.9 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.9 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 3.6 GO:0000792 heterochromatin(GO:0000792)
0.0 8.0 GO:0043235 receptor complex(GO:0043235)
0.0 0.4 GO:0030914 STAGA complex(GO:0030914)
0.0 0.6 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 1.9 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.6 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 1.1 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 1.7 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 1.4 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.9 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.7 GO:0070469 respiratory chain(GO:0070469)
0.0 4.8 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 0.4 GO:0048786 presynaptic active zone(GO:0048786)
0.0 1.1 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.2 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.1 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.3 GO:0071565 nBAF complex(GO:0071565)
0.0 5.1 GO:0016607 nuclear speck(GO:0016607)
0.0 0.5 GO:0034707 chloride channel complex(GO:0034707)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.7 10.7 GO:0005118 sevenless binding(GO:0005118)
1.4 5.6 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
1.3 5.0 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
1.2 3.6 GO:0003870 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
1.1 5.5 GO:0005345 purine nucleobase transmembrane transporter activity(GO:0005345) pyrimidine nucleobase transmembrane transporter activity(GO:0005350) nucleobase transmembrane transporter activity(GO:0015205) glycerol channel activity(GO:0015254)
0.8 2.3 GO:0030021 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.7 2.1 GO:0015152 glucose-6-phosphate transmembrane transporter activity(GO:0015152)
0.6 2.3 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.5 1.6 GO:0001571 non-tyrosine kinase fibroblast growth factor receptor activity(GO:0001571)
0.5 5.8 GO:0004859 phospholipase inhibitor activity(GO:0004859)
0.5 3.7 GO:0019770 IgG receptor activity(GO:0019770)
0.5 1.5 GO:0005148 prolactin receptor binding(GO:0005148)
0.5 1.8 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.4 1.3 GO:0030298 receptor signaling protein tyrosine kinase activator activity(GO:0030298)
0.3 1.0 GO:0000171 ribonuclease MRP activity(GO:0000171)
0.3 1.3 GO:0015222 serotonin transmembrane transporter activity(GO:0015222)
0.3 7.2 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.3 1.5 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.3 0.9 GO:0004613 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
0.2 3.3 GO:0004000 adenosine deaminase activity(GO:0004000)
0.2 3.2 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.2 1.4 GO:0015091 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.2 0.6 GO:0071820 N-box binding(GO:0071820)
0.2 4.9 GO:0019825 oxygen binding(GO:0019825)
0.2 5.6 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.2 1.6 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.2 1.2 GO:0034056 estrogen response element binding(GO:0034056)
0.2 1.7 GO:0005000 vasopressin receptor activity(GO:0005000)
0.2 1.0 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.2 1.5 GO:0016892 endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892)
0.2 3.4 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.2 1.1 GO:0004966 galanin receptor activity(GO:0004966)
0.2 1.4 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.2 2.6 GO:1901702 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.2 1.4 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.1 2.1 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.1 3.3 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.1 9.0 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.1 0.8 GO:0070699 type II activin receptor binding(GO:0070699)
0.1 0.5 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.1 1.2 GO:0050692 DBD domain binding(GO:0050692)
0.1 2.0 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.1 0.7 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.1 0.6 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.1 13.2 GO:0005550 pheromone binding(GO:0005550)
0.1 1.1 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.1 2.0 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.1 1.1 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.1 0.7 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.1 1.8 GO:0044548 S100 protein binding(GO:0044548)
0.1 3.9 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.1 2.7 GO:0005234 extracellular-glutamate-gated ion channel activity(GO:0005234)
0.1 0.7 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.1 2.4 GO:0003680 AT DNA binding(GO:0003680)
0.1 0.6 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.1 0.5 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.1 0.7 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.1 2.0 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.1 0.3 GO:0008311 double-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008311)
0.1 1.6 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.1 0.8 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.1 4.5 GO:0003743 translation initiation factor activity(GO:0003743)
0.1 1.6 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.1 0.3 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
0.1 1.4 GO:0050811 GABA receptor binding(GO:0050811)
0.1 1.4 GO:0017081 chloride channel regulator activity(GO:0017081)
0.1 0.2 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.1 2.2 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.1 0.9 GO:0003688 DNA replication origin binding(GO:0003688)
0.1 2.0 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.1 0.7 GO:0097109 neuroligin family protein binding(GO:0097109)
0.0 8.5 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 16.6 GO:0005549 odorant binding(GO:0005549)
0.0 0.2 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.0 1.6 GO:0008392 arachidonic acid epoxygenase activity(GO:0008392) aromatase activity(GO:0070330)
0.0 2.4 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.7 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 2.2 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 9.7 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.4 GO:0004768 stearoyl-CoA 9-desaturase activity(GO:0004768)
0.0 3.1 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 6.0 GO:0001191 transcriptional repressor activity, RNA polymerase II transcription factor binding(GO:0001191)
0.0 0.7 GO:0003796 lysozyme activity(GO:0003796)
0.0 1.2 GO:0022829 wide pore channel activity(GO:0022829)
0.0 1.2 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.5 GO:0004908 interleukin-1 receptor activity(GO:0004908)
0.0 3.8 GO:0008276 protein methyltransferase activity(GO:0008276)
0.0 0.5 GO:0043495 protein anchor(GO:0043495)
0.0 0.7 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 6.4 GO:0003774 motor activity(GO:0003774)
0.0 0.1 GO:0043532 angiostatin binding(GO:0043532)
0.0 0.8 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.4 GO:0048185 activin binding(GO:0048185)
0.0 26.6 GO:0005198 structural molecule activity(GO:0005198)
0.0 0.2 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.0 0.6 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.1 GO:0033142 progesterone receptor binding(GO:0033142)
0.0 1.1 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 1.2 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 21.2 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 2.2 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 1.6 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 1.2 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.4 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 2.0 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 0.2 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
0.0 3.0 GO:0016779 nucleotidyltransferase activity(GO:0016779)
0.0 0.6 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.9 GO:0030507 spectrin binding(GO:0030507)
0.0 0.3 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 0.4 GO:0070402 NADPH binding(GO:0070402)
0.0 0.2 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 3.9 GO:0008236 serine-type peptidase activity(GO:0008236)
0.0 0.1 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.3 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.3 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.0 0.5 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.3 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 1.9 GO:0015293 symporter activity(GO:0015293)
0.0 0.2 GO:0005521 lamin binding(GO:0005521)
0.0 0.3 GO:0043274 phospholipase binding(GO:0043274)
0.0 1.0 GO:0031072 heat shock protein binding(GO:0031072)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 9.7 PID ALK1 PATHWAY ALK1 signaling events
0.1 4.5 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.1 3.2 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.1 3.0 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 12.4 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.1 4.1 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.1 3.0 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.1 4.9 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.1 0.2 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 2.4 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 3.4 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 2.1 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 0.8 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 3.1 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.0 1.8 PID FGF PATHWAY FGF signaling pathway
0.0 1.1 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.3 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 1.2 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.5 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.6 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.0 0.6 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 1.5 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 1.8 PID CMYB PATHWAY C-MYB transcription factor network
0.0 1.3 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.3 ST GA12 PATHWAY G alpha 12 Pathway
0.0 0.5 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.5 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 0.6 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.4 PID INSULIN PATHWAY Insulin Pathway
0.0 0.6 PID REG GR PATHWAY Glucocorticoid receptor regulatory network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 5.5 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.3 4.9 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.3 4.5 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.2 3.7 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.2 3.6 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.1 8.8 REACTOME MYOGENESIS Genes involved in Myogenesis
0.1 3.2 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.1 1.1 REACTOME OPSINS Genes involved in Opsins
0.1 3.4 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1 1.8 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.1 0.9 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.1 2.2 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 1.2 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.1 2.9 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.1 0.7 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.1 1.9 REACTOME AMYLOIDS Genes involved in Amyloids
0.1 1.4 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.1 0.9 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.1 0.6 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 2.9 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 2.2 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.4 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 2.2 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.0 0.5 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.0 0.7 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 1.9 REACTOME GLUCAGON TYPE LIGAND RECEPTORS Genes involved in Glucagon-type ligand receptors
0.0 0.5 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.7 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.9 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.0 0.6 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.5 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 1.7 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.7 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.9 REACTOME L1CAM INTERACTIONS Genes involved in L1CAM interactions
0.0 2.6 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.4 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.5 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.4 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.6 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression