ISMARA results: Zbtb12

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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Zbtb12

Z-value: 1.19

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Transcription factors associated with Zbtb12

Gene Symbol	Gene ID	Gene Info
Zbtb12 Ensembl NCBI MGI UniProt	ENSMUSG00000049823.10	Zbtb12

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
Zbtb12	mm39_v1_chr17_+_35113490_35113554	-0.21	8.1e-02	Click!

Activity profile of Zbtb12 motif

Sorted Z-values of Zbtb12 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Zbtb12

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Promoter	Score	Transcript	Gene	Gene Info
chr9_+_36604516 Show fit	17.50	ENSMUST00000034620.5	Acrv1 Ensembl NCBI MGI UniProt Show fit	acrosomal vesicle protein 1
chr15_-_76419131 Show fit	17.18	ENSMUST00000230604.2	Tmem249 Ensembl NCBI MGI UniProt Show fit	transmembrane protein 249
chr5_-_142515792 Show fit	16.75	ENSMUST00000099400.3	Papolb Ensembl NCBI MGI UniProt Show fit	poly (A) polymerase beta (testis specific)
chr11_+_100332709 Show fit	15.41	ENSMUST00000001599.4 ENSMUST00000107395.3	Klhl10 Ensembl NCBI MGI UniProt Show fit	kelch-like 10
chr7_-_126574959 Show fit	12.42	ENSMUST00000206296.2 ENSMUST00000205437.3	Cdiptos Ensembl NCBI MGI UniProt Show fit	CDIP transferase, opposite strand
chr7_+_140427711 Show fit	12.31	ENSMUST00000026555.12	Odf3 Ensembl NCBI MGI UniProt Show fit	outer dense fiber of sperm tails 3
chr8_+_41128099 Show fit	11.94	ENSMUST00000051614.5	Adam24 Ensembl NCBI MGI UniProt Show fit	a disintegrin and metallopeptidase domain 24 (testase 1)
chr9_+_110673565 Show fit	10.81	ENSMUST00000176403.8	Prss46 Ensembl NCBI MGI UniProt Show fit	protease, serine 46
chr18_+_70605722 Show fit	10.69	ENSMUST00000174118.8	Stard6 Ensembl NCBI MGI UniProt Show fit	StAR-related lipid transfer (START) domain containing 6
chr7_+_140427729 Show fit	10.65	ENSMUST00000106049.2	Odf3 Ensembl NCBI MGI UniProt Show fit	outer dense fiber of sperm tails 3

Showing 1 to 10 of 119 entries

Gene Ontology Analysis

Gene overrepresentation in biological process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	58.9	GO:0007283	spermatogenesis(GO:0007283)
0.1	40.7	GO:0006869	lipid transport(GO:0006869)
0.3	16.7	GO:0006378	mRNA polyadenylation(GO:0006378) RNA polyadenylation(GO:0043631)
2.6	15.4	GO:0048808	male genitalia morphogenesis(GO:0048808) male anatomical structure morphogenesis(GO:0090598)
0.8	14.8	GO:0016998	cell wall macromolecule catabolic process(GO:0016998)
1.7	11.9	GO:0060468	prevention of polyspermy(GO:0060468)
0.5	9.7	GO:0043312	neutrophil degranulation(GO:0043312)
0.5	9.0	GO:0036159	inner dynein arm assembly(GO:0036159)
0.8	8.6	GO:0070345	negative regulation of fat cell proliferation(GO:0070345)
0.8	8.4	GO:0006686	sphingomyelin biosynthetic process(GO:0006686)

Showing 1 to 10 of 57 entries

Gene overrepresentation in cellular component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	33.2	GO:0005739	mitochondrion(GO:0005739)
1.6	23.0	GO:0001520	outer dense fiber(GO:0001520)
0.1	17.5	GO:0001669	acrosomal vesicle(GO:0001669)
0.2	15.4	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)
0.7	9.7	GO:0030670	phagocytic vesicle membrane(GO:0030670)
0.7	9.0	GO:0005858	axonemal dynein complex(GO:0005858) inner dynein arm(GO:0036156)
0.2	8.4	GO:0030173	integral component of Golgi membrane(GO:0030173)
0.1	8.4	GO:0032809	neuronal cell body membrane(GO:0032809)
0.1	8.3	GO:0005758	mitochondrial intermembrane space(GO:0005758)
0.2	7.7	GO:0002080	acrosomal membrane(GO:0002080)

Showing 1 to 10 of 31 entries

Gene overrepresentation in molecular function category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.3	42.2	GO:0004222	metalloendopeptidase activity(GO:0004222)
0.5	40.7	GO:0015485	cholesterol binding(GO:0015485)
0.0	19.8	GO:0004842	ubiquitin-protein transferase activity(GO:0004842)
3.3	16.7	GO:0004652	polynucleotide adenylyltransferase activity(GO:0004652)
0.5	16.2	GO:0008569	ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.8	14.8	GO:0003796	lysozyme activity(GO:0003796)
0.1	11.9	GO:0004252	serine-type endopeptidase activity(GO:0004252)
1.1	9.7	GO:0019834	phospholipase A2 inhibitor activity(GO:0019834)
0.2	8.7	GO:0004364	glutathione transferase activity(GO:0004364)
1.4	8.4	GO:0047493	sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)

Showing 1 to 10 of 40 entries

Gene overrepresentation in curated gene sets: canonical pathways category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	15.5	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0	9.7	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1	7.3	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
0.1	5.1	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.1	4.1	PID IL23 PATHWAY	IL23-mediated signaling events
0.0	2.8	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.1	1.4	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0	1.3	PID RHODOPSIN PATHWAY	Visual signal transduction: Rods
0.0	1.3	PID BCR 5PATHWAY	BCR signaling pathway
0.0	1.1	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5

Showing 1 to 10 of 14 entries

Gene overrepresentation in curated gene sets: REACTOME pathways category:

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Log-likelihood per target	Total log-likelihood	Term	Description
1.0	40.7	REACTOME STEROID HORMONES	Genes involved in Steroid hormones
0.2	8.9	REACTOME MEIOTIC RECOMBINATION	Genes involved in Meiotic Recombination
0.2	8.5	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.2	8.4	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.0	5.1	REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS	Genes involved in Class B/2 (Secretin family receptors)
0.0	4.8	REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION	Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.1	2.7	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0	2.6	REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0	1.4	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.0	1.3	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers

Showing 1 to 10 of 15 entries

Results for Zbtb12

Z-value: 1.19

Motif logo

Transcription factors associated with Zbtb12

Activity-expression correlation:

Activity profile of Zbtb12 motif

Sorted Z-values of Zbtb12 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Zbtb12

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.

Top targets:

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: