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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Zbtb12

Z-value: 1.19

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Transcription factors associated with Zbtb12

Gene Symbol Gene ID Gene Info
Zbtb12
ENSMUSG00000049823.10 Zbtb12

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Zbtb12mm39_v1_chr17_+_35113490_35113554-0.218.1e-02Click!

Activity profile of Zbtb12 motif

Sorted Z-values of Zbtb12 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Zbtb12

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr9_+_36604516 17.50 ENSMUST00000034620.5
Acrv1
acrosomal vesicle protein 1
chr15_-_76419131 17.18 ENSMUST00000230604.2
Tmem249
transmembrane protein 249
chr5_-_142515792 16.75 ENSMUST00000099400.3
Papolb
poly (A) polymerase beta (testis specific)
chr11_+_100332709 15.41 ENSMUST00000001599.4
ENSMUST00000107395.3
Klhl10
kelch-like 10
chr7_-_126574959 12.42 ENSMUST00000206296.2
ENSMUST00000205437.3
Cdiptos
CDIP transferase, opposite strand
chr7_+_140427711 12.31 ENSMUST00000026555.12
Odf3
outer dense fiber of sperm tails 3
chr8_+_41128099 11.94 ENSMUST00000051614.5
Adam24
a disintegrin and metallopeptidase domain 24 (testase 1)
chr9_+_110673565 10.81 ENSMUST00000176403.8
Prss46
protease, serine 46
chr18_+_70605722 10.69 ENSMUST00000174118.8
Stard6
StAR-related lipid transfer (START) domain containing 6
chr7_+_140427729 10.65 ENSMUST00000106049.2
Odf3
outer dense fiber of sperm tails 3
chr18_+_70605691 10.55 ENSMUST00000164223.8
Stard6
StAR-related lipid transfer (START) domain containing 6
chr18_+_70605630 10.03 ENSMUST00000168249.9
Stard6
StAR-related lipid transfer (START) domain containing 6
chr5_+_96989853 9.71 ENSMUST00000196126.2
Anxa3
annexin A3
chr8_-_44029744 9.70 ENSMUST00000049577.3
Adam26a
a disintegrin and metallopeptidase domain 26A (testase 3)
chr18_+_70605476 9.42 ENSMUST00000114959.9
Stard6
StAR-related lipid transfer (START) domain containing 6
chr11_+_104983022 9.25 ENSMUST00000021029.6
Efcab3
EF-hand calcium binding domain 3
chr5_-_121641461 9.12 ENSMUST00000079368.5
Adam1b
a disintegrin and metallopeptidase domain 1b
chr14_+_26414422 8.99 ENSMUST00000022433.12
Dnah12
dynein, axonemal, heavy chain 12
chr8_+_41246310 8.97 ENSMUST00000056331.8
Adam20
a disintegrin and metallopeptidase domain 20
chr10_-_75658355 8.71 ENSMUST00000160211.2
Gstt4
glutathione S-transferase, theta 4
chr4_-_43669141 8.70 ENSMUST00000056474.7
Fam221b
family with sequence similarity 221, member B
chr7_-_25239229 8.61 ENSMUST00000044547.10
ENSMUST00000066503.14
ENSMUST00000064862.13
Ceacam2
carcinoembryonic antigen-related cell adhesion molecule 2
chr11_+_102775991 8.47 ENSMUST00000100369.4
Fam187a
family with sequence similarity 187, member A
chr3_-_131138541 8.38 ENSMUST00000090246.5
ENSMUST00000126569.2
Sgms2
sphingomyelin synthase 2
chr17_+_27248233 8.34 ENSMUST00000053683.7
ENSMUST00000236222.2
Ggnbp1
gametogenetin binding protein 1
chr1_-_161807205 8.33 ENSMUST00000162676.2
4930558K02Rik
RIKEN cDNA 4930558K02 gene
chr18_+_4165832 7.99 ENSMUST00000025076.10
Lyzl1
lysozyme-like 1
chr6_+_29398919 7.70 ENSMUST00000181464.8
ENSMUST00000180829.8
Ccdc136
coiled-coil domain containing 136
chr8_+_41205245 7.53 ENSMUST00000096663.5
Adam25
a disintegrin and metallopeptidase domain 25 (testase 2)
chr8_+_71156071 7.50 ENSMUST00000212436.2
Iqcn
IQ motif containing N
chr6_-_83504756 7.30 ENSMUST00000152029.2
Actg2
actin, gamma 2, smooth muscle, enteric
chr11_-_118021460 7.19 ENSMUST00000132685.9
Dnah17
dynein, axonemal, heavy chain 17
chr1_+_69866145 7.16 ENSMUST00000065425.12
ENSMUST00000113940.4
Spag16
sperm associated antigen 16
chr15_-_88838605 7.07 ENSMUST00000109371.8
Ttll8
tubulin tyrosine ligase-like family, member 8
chr17_-_57181420 7.05 ENSMUST00000043062.5
Acsbg2
acyl-CoA synthetase bubblegum family member 2
chr18_+_4165856 6.84 ENSMUST00000120837.2
Lyzl1
lysozyme-like 1
chr11_-_70590923 6.72 ENSMUST00000108543.4
ENSMUST00000108542.8
ENSMUST00000108541.9
ENSMUST00000126114.9
ENSMUST00000073625.8
Inca1
inhibitor of CDK, cyclin A1 interacting protein 1
chr19_+_6130059 6.66 ENSMUST00000149347.8
ENSMUST00000143303.2
Tmem262
transmembrane protein 262
chr8_+_41276027 6.47 ENSMUST00000066814.7
Adam39
a disintegrin and metallopeptidase domain 39
chr15_-_76259126 6.40 ENSMUST00000071119.8
Tssk5
testis-specific serine kinase 5
chr6_+_24528143 6.39 ENSMUST00000031696.10
Asb15
ankyrin repeat and SOCS box-containing 15
chr8_-_43981143 6.10 ENSMUST00000080135.5
Adam26b
a disintegrin and metallopeptidase domain 26B
chrX_+_106836189 6.01 ENSMUST00000101292.9
Tent5d
terminal nucleotidyltransferase 5D
chr7_+_99825886 5.80 ENSMUST00000178946.9
Kcne3
potassium voltage-gated channel, Isk-related subfamily, gene 3
chr17_+_79934096 5.48 ENSMUST00000224618.2
Rmdn2
regulator of microtubule dynamics 2
chr15_-_98796373 5.14 ENSMUST00000229775.2
ENSMUST00000023737.6
Dhh
desert hedgehog
chr10_+_63293284 5.05 ENSMUST00000105440.8
Ctnna3
catenin (cadherin associated protein), alpha 3
chr2_+_148623929 4.96 ENSMUST00000028933.3
Cstdc1
cystatin domain containing 1
chr6_-_143892814 4.78 ENSMUST00000124233.7
ENSMUST00000144289.4
ENSMUST00000111748.8
Sox5
SRY (sex determining region Y)-box 5
chr5_+_11234174 4.53 ENSMUST00000168407.3
Gm5861
predicted gene 5861
chr6_+_103674695 4.21 ENSMUST00000205098.2
Chl1
cell adhesion molecule L1-like
chr7_+_24476597 4.15 ENSMUST00000038069.9
ENSMUST00000206847.2
Ceacam10
carcinoembryonic antigen-related cell adhesion molecule 10
chr11_+_87684299 4.11 ENSMUST00000020779.11
Mpo
myeloperoxidase
chr12_-_81615248 3.90 ENSMUST00000008582.4
Adam21
a disintegrin and metallopeptidase domain 21
chr11_+_108271990 3.45 ENSMUST00000146050.2
ENSMUST00000152958.8
Apoh
apolipoprotein H
chr3_-_153610368 3.44 ENSMUST00000188338.7
Msh4
mutS homolog 4
chr1_-_75208734 3.34 ENSMUST00000180101.3
A630095N17Rik
RIKEN cDNA A630095N17 gene
chr3_-_153610528 3.28 ENSMUST00000190449.2
Msh4
mutS homolog 4
chr7_+_106413336 3.28 ENSMUST00000166880.3
ENSMUST00000075414.8
Olfr701
olfactory receptor 701
chrX_+_71265623 3.13 ENSMUST00000048675.2
Magea4
MAGE family member A4
chr4_-_138351313 2.84 ENSMUST00000030533.12
Vwa5b1
von Willebrand factor A domain containing 5B1
chr10_-_70428611 2.67 ENSMUST00000162251.8
Phyhipl
phytanoyl-CoA hydroxylase interacting protein-like
chr13_+_104365880 2.67 ENSMUST00000022227.8
Cenpk
centromere protein K
chr16_-_94657531 2.56 ENSMUST00000232562.2
ENSMUST00000165538.3
Kcnj6
potassium inwardly-rectifying channel, subfamily J, member 6
chr5_+_30486375 2.53 ENSMUST00000101448.5
Drc1
dynein regulatory complex subunit 1
chr15_+_82225380 2.37 ENSMUST00000050349.3
Pheta2
PH domain containing endocytic trafficking adaptor 2
chr9_-_122673080 2.37 ENSMUST00000203176.3
ENSMUST00000203656.3
ENSMUST00000204619.2
Gm35549
predicted gene, 35549
chr3_-_84063067 2.23 ENSMUST00000047368.8
Mnd1
meiotic nuclear divisions 1
chr14_-_79718890 2.17 ENSMUST00000022601.7
Wbp4
WW domain binding protein 4
chr2_-_28806639 1.97 ENSMUST00000113847.3
Barhl1
BarH like homeobox 1
chr18_-_70605538 1.94 ENSMUST00000067556.4
4930503L19Rik
RIKEN cDNA 4930503L19 gene
chr7_+_100966289 1.87 ENSMUST00000163799.9
ENSMUST00000164479.9
Stard10
START domain containing 10
chr1_+_170472092 1.85 ENSMUST00000046792.9
Olfml2b
olfactomedin-like 2B
chr13_-_64645606 1.71 ENSMUST00000180282.2
Fam240b
family with sequence similarity 240 member B
chr19_-_46561532 1.59 ENSMUST00000026009.10
ENSMUST00000236255.2
Arl3
ADP-ribosylation factor-like 3
chr14_+_67470884 1.47 ENSMUST00000176161.8
Ebf2
early B cell factor 2
chr7_-_48493388 1.39 ENSMUST00000167786.4
Csrp3
cysteine and glycine-rich protein 3
chr4_+_119396913 1.37 ENSMUST00000137560.8
Foxj3
forkhead box J3
chr19_+_6919691 1.36 ENSMUST00000113426.8
ENSMUST00000238184.2
ENSMUST00000113423.10
ENSMUST00000237334.2
ENSMUST00000235240.2
Bad
BCL2-associated agonist of cell death
chr4_-_151142351 1.35 ENSMUST00000030797.4
Vamp3
vesicle-associated membrane protein 3
chr17_+_28128307 1.30 ENSMUST00000233525.2
ENSMUST00000025058.15
ENSMUST00000233866.2
Anks1
ankyrin repeat and SAM domain containing 1
chr5_-_35836761 1.30 ENSMUST00000114233.3
Htra3
HtrA serine peptidase 3
chr2_+_129854256 1.29 ENSMUST00000110299.3
Tgm3
transglutaminase 3, E polypeptide
chr7_+_24596806 1.27 ENSMUST00000003469.8
Cd79a
CD79A antigen (immunoglobulin-associated alpha)
chr7_-_35285001 1.26 ENSMUST00000069912.6
Rgs9bp
regulator of G-protein signalling 9 binding protein
chr17_+_18051266 1.25 ENSMUST00000172097.9
Spaca6
sperm acrosome associated 6
chr14_-_70449438 1.24 ENSMUST00000227929.2
Sorbs3
sorbin and SH3 domain containing 3
chr9_+_123902143 1.18 ENSMUST00000168841.3
ENSMUST00000055918.7
Ccr2
chemokine (C-C motif) receptor 2
chr4_-_119031050 1.08 ENSMUST00000052715.10
ENSMUST00000179290.8
ENSMUST00000154226.2
Zfp691
zinc finger protein 691
chr14_+_79718604 1.06 ENSMUST00000040131.13
Elf1
E74-like factor 1
chr1_-_155627430 0.96 ENSMUST00000195275.2
Lhx4
LIM homeobox protein 4
chr12_-_101924407 0.84 ENSMUST00000159883.2
ENSMUST00000160251.8
ENSMUST00000161011.8
ENSMUST00000021606.12
Atxn3
ataxin 3
chr14_+_26789345 0.76 ENSMUST00000226105.2
Il17rd
interleukin 17 receptor D
chr11_-_100332619 0.74 ENSMUST00000107398.8
Nt5c3b
5'-nucleotidase, cytosolic IIIB
chr17_+_37253916 0.74 ENSMUST00000173072.2
Rnf39
ring finger protein 39
chr3_+_87989278 0.71 ENSMUST00000071812.11
Iqgap3
IQ motif containing GTPase activating protein 3
chr14_+_54406112 0.68 ENSMUST00000103694.3
ENSMUST00000199452.2
Traj49
T cell receptor alpha joining 49
chr17_-_28128180 0.64 ENSMUST00000114848.8
Taf11
TATA-box binding protein associated factor 11
chr2_-_150531280 0.63 ENSMUST00000046095.10
Vsx1
visual system homeobox 1
chr6_+_37877413 0.61 ENSMUST00000120238.2
Trim24
tripartite motif-containing 24
chr9_+_22322802 0.57 ENSMUST00000058868.9
9530077C05Rik
RIKEN cDNA 9530077C05 gene
chr4_+_43669266 0.57 ENSMUST00000107864.8
Tmem8b
transmembrane protein 8B
chr9_-_62895197 0.53 ENSMUST00000216209.2
Pias1
protein inhibitor of activated STAT 1
chr5_+_92750898 0.49 ENSMUST00000200941.2
ENSMUST00000050952.4
Stbd1
starch binding domain 1
chr15_-_60793115 0.47 ENSMUST00000096418.5
A1bg
alpha-1-B glycoprotein
chr3_+_5283577 0.45 ENSMUST00000175866.8
Zfhx4
zinc finger homeodomain 4
chr17_-_28779678 0.40 ENSMUST00000114785.3
ENSMUST00000025062.5
Clps
colipase, pancreatic
chr3_+_5283606 0.37 ENSMUST00000026284.13
Zfhx4
zinc finger homeodomain 4
chr4_-_149994176 0.37 ENSMUST00000105685.2
Spsb1
splA/ryanodine receptor domain and SOCS box containing 1
chr16_-_89368059 0.28 ENSMUST00000171542.2
Krtap11-1
keratin associated protein 11-1
chr11_+_69881885 0.25 ENSMUST00000018711.15
Gabarap
gamma-aminobutyric acid receptor associated protein
chr12_+_111540920 0.24 ENSMUST00000075281.8
ENSMUST00000084953.13
Mark3
MAP/microtubule affinity regulating kinase 3
chr7_+_35285657 0.14 ENSMUST00000040844.16
ENSMUST00000188906.7
ENSMUST00000186245.7
ENSMUST00000190503.7
Ankrd27
ankyrin repeat domain 27 (VPS9 domain)
chr17_+_48607405 0.12 ENSMUST00000170941.3
Treml2
triggering receptor expressed on myeloid cells-like 2
chr8_-_70411054 0.09 ENSMUST00000211960.2
Gatad2a
GATA zinc finger domain containing 2A
chr9_+_22322875 0.04 ENSMUST00000214436.2
9530077C05Rik
RIKEN cDNA 9530077C05 gene
chr17_+_83658354 0.03 ENSMUST00000096766.12
ENSMUST00000049503.10
ENSMUST00000112363.10
ENSMUST00000234460.2
Eml4
echinoderm microtubule associated protein like 4
chr1_+_38037086 0.01 ENSMUST00000027252.8
Eif5b
eukaryotic translation initiation factor 5B
chr7_+_102420428 0.00 ENSMUST00000213432.2
Olfr561
olfactory receptor 561

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.6 15.4 GO:0048808 male genitalia morphogenesis(GO:0048808) male anatomical structure morphogenesis(GO:0090598)
2.6 5.1 GO:0030908 intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908)
1.7 11.9 GO:0060468 prevention of polyspermy(GO:0060468)
1.4 5.8 GO:1902303 negative regulation of potassium ion export(GO:1902303)
1.4 4.1 GO:0002148 hypochlorous acid metabolic process(GO:0002148) hypochlorous acid biosynthetic process(GO:0002149)
1.2 7.1 GO:0018094 protein polyglycylation(GO:0018094)
1.0 7.2 GO:0051012 microtubule sliding(GO:0051012)
0.8 8.4 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.8 14.8 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.8 8.6 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.7 4.8 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.6 5.0 GO:0086073 bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.5 9.0 GO:0036159 inner dynein arm assembly(GO:0036159)
0.5 9.7 GO:0043312 neutrophil degranulation(GO:0043312)
0.5 1.4 GO:1903920 positive regulation of actin filament severing(GO:1903920)
0.5 1.4 GO:1902220 positive regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902220)
0.4 3.4 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.4 6.7 GO:0051026 chiasma assembly(GO:0051026)
0.4 1.2 GO:2000451 immune complex clearance by monocytes and macrophages(GO:0002436) regulation of immune complex clearance by monocytes and macrophages(GO:0090264) positive regulation of immune complex clearance by monocytes and macrophages(GO:0090265) negative regulation of eosinophil activation(GO:1902567) positive regulation of CD8-positive, alpha-beta T cell extravasation(GO:2000451)
0.4 7.7 GO:0001675 acrosome assembly(GO:0001675)
0.3 16.7 GO:0006378 mRNA polyadenylation(GO:0006378) RNA polyadenylation(GO:0043631)
0.2 1.0 GO:0021526 medial motor column neuron differentiation(GO:0021526)
0.2 2.5 GO:0070286 axonemal dynein complex assembly(GO:0070286)
0.2 1.9 GO:0035360 positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360)
0.2 6.7 GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
0.2 0.5 GO:0061723 glycophagy(GO:0061723)
0.1 7.2 GO:0003341 cilium movement(GO:0003341)
0.1 8.3 GO:0000266 mitochondrial fission(GO:0000266)
0.1 2.2 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.1 4.1 GO:0030317 sperm motility(GO:0030317)
0.1 1.1 GO:1901187 regulation of ephrin receptor signaling pathway(GO:1901187)
0.1 1.2 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.1 40.7 GO:0006869 lipid transport(GO:0006869)
0.1 0.6 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.1 58.9 GO:0007283 spermatogenesis(GO:0007283)
0.1 2.6 GO:0042403 thyroid hormone metabolic process(GO:0042403)
0.1 2.2 GO:0035825 reciprocal meiotic recombination(GO:0007131) reciprocal DNA recombination(GO:0035825)
0.1 1.5 GO:0035493 SNARE complex assembly(GO:0035493)
0.1 0.8 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520) positive regulation of ERAD pathway(GO:1904294)
0.1 1.5 GO:0035563 positive regulation of chromatin binding(GO:0035563)
0.1 1.3 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.1 0.6 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.0 0.7 GO:0033601 positive regulation of mammary gland epithelial cell proliferation(GO:0033601)
0.0 0.5 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0 0.2 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 1.3 GO:0031424 keratinization(GO:0031424)
0.0 2.9 GO:0006749 glutathione metabolic process(GO:0006749)
0.0 0.6 GO:0043923 positive regulation by host of viral transcription(GO:0043923)
0.0 1.6 GO:0035640 exploration behavior(GO:0035640)
0.0 2.0 GO:0030901 midbrain development(GO:0030901)
0.0 1.1 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 1.6 GO:0042073 intraciliary transport(GO:0042073)
0.0 1.2 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
0.0 1.2 GO:0051496 positive regulation of stress fiber assembly(GO:0051496)
0.0 0.3 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.4 GO:0032094 response to food(GO:0032094)
0.0 1.3 GO:0051289 protein homotetramerization(GO:0051289)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 7.2 GO:1990716 axonemal central apparatus(GO:1990716)
1.6 23.0 GO:0001520 outer dense fiber(GO:0001520)
1.1 6.7 GO:0005713 recombination nodule(GO:0005713)
0.7 9.7 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.7 7.2 GO:0036157 outer dynein arm(GO:0036157)
0.7 9.0 GO:0005858 axonemal dynein complex(GO:0005858) inner dynein arm(GO:0036156)
0.2 4.1 GO:0005766 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.2 5.0 GO:0005916 fascia adherens(GO:0005916)
0.2 7.7 GO:0002080 acrosomal membrane(GO:0002080)
0.2 6.6 GO:0042101 T cell receptor complex(GO:0042101)
0.2 1.3 GO:0019815 B cell receptor complex(GO:0019815)
0.2 15.4 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.2 8.4 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.1 3.4 GO:0042627 chylomicron(GO:0042627)
0.1 8.4 GO:0032809 neuronal cell body membrane(GO:0032809)
0.1 17.5 GO:0001669 acrosomal vesicle(GO:0001669)
0.1 1.9 GO:0046581 intercellular canaliculus(GO:0046581)
0.1 8.3 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.1 0.6 GO:0005726 perichromatin fibrils(GO:0005726)
0.1 7.3 GO:0005930 axoneme(GO:0005930)
0.0 1.6 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.8 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 1.4 GO:0030665 clathrin-coated vesicle membrane(GO:0030665)
0.0 1.3 GO:0001533 cornified envelope(GO:0001533)
0.0 5.4 GO:0044798 nuclear transcription factor complex(GO:0044798)
0.0 0.1 GO:0097422 tubular endosome(GO:0097422)
0.0 5.2 GO:0000151 ubiquitin ligase complex(GO:0000151)
0.0 1.3 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 33.2 GO:0005739 mitochondrion(GO:0005739)
0.0 3.1 GO:0072562 blood microparticle(GO:0072562)
0.0 6.1 GO:0005578 proteinaceous extracellular matrix(GO:0005578)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
3.3 16.7 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
1.8 7.1 GO:0070736 protein-glycine ligase activity, initiating(GO:0070736)
1.4 8.4 GO:0047493 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
1.1 9.7 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.9 5.1 GO:0005113 patched binding(GO:0005113)
0.8 14.8 GO:0003796 lysozyme activity(GO:0003796)
0.6 3.4 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.5 16.2 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.5 40.7 GO:0015485 cholesterol binding(GO:0015485)
0.5 6.7 GO:0030983 mismatched DNA binding(GO:0030983)
0.5 5.0 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.4 1.2 GO:0035717 chemokine (C-C motif) ligand 7 binding(GO:0035717)
0.4 7.1 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.3 6.7 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.3 7.6 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.3 42.2 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.3 2.6 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.2 1.4 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.2 8.7 GO:0004364 glutathione transferase activity(GO:0004364)
0.1 1.3 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.1 0.8 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.1 0.7 GO:0032027 myosin light chain binding(GO:0032027)
0.1 0.5 GO:2001070 glycogen binding(GO:2001069) starch binding(GO:2001070)
0.1 1.4 GO:0030346 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656) protein phosphatase 2B binding(GO:0030346)
0.1 0.6 GO:0034056 estrogen response element binding(GO:0034056)
0.1 0.8 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.1 0.5 GO:0061665 SUMO ligase activity(GO:0061665)
0.1 5.8 GO:0015459 potassium channel regulator activity(GO:0015459)
0.1 2.1 GO:0070064 proline-rich region binding(GO:0070064)
0.1 11.9 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 1.4 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.6 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 1.2 GO:0017166 vinculin binding(GO:0017166)
0.0 0.7 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 19.8 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 4.1 GO:0020037 heme binding(GO:0020037)
0.0 1.8 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 1.1 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 2.5 GO:0002020 protease binding(GO:0002020)
0.0 0.3 GO:0050811 GABA receptor binding(GO:0050811)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 5.1 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.1 7.3 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.1 4.1 PID IL23 PATHWAY IL23-mediated signaling events
0.1 1.4 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.1 15.5 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 9.7 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.5 ST JAK STAT PATHWAY Jak-STAT Pathway
0.0 1.3 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 1.1 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 1.3 PID BCR 5PATHWAY BCR signaling pathway
0.0 2.8 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.8 PID FGF PATHWAY FGF signaling pathway
0.0 0.5 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 0.7 PID RAC1 PATHWAY RAC1 signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 40.7 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.2 8.9 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.2 8.4 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.2 8.5 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 1.2 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.1 2.7 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.1 0.4 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0 5.1 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 1.4 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 2.6 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 1.3 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.5 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.6 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 4.8 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.6 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening