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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Zbtb49

Z-value: 0.49

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Transcription factors associated with Zbtb49

Gene Symbol Gene ID Gene Info
Zbtb49
ENSMUSG00000029127.16 Zbtb49

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Zbtb49mm39_v1_chr5_-_38377746_38377801-0.371.4e-03Click!

Activity profile of Zbtb49 motif

Sorted Z-values of Zbtb49 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Zbtb49

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr6_+_71176811 10.55 ENSMUST00000067492.8
Fabp1
fatty acid binding protein 1, liver
chr19_-_39637489 7.44 ENSMUST00000067328.7
Cyp2c67
cytochrome P450, family 2, subfamily c, polypeptide 67
chr15_-_34495329 6.13 ENSMUST00000022946.6
Rida
reactive intermediate imine deaminase A homolog
chr7_-_139734637 3.57 ENSMUST00000059241.8
Sprn
shadow of prion protein
chr17_+_24955613 3.10 ENSMUST00000115262.9
Msrb1
methionine sulfoxide reductase B1
chr17_+_24955647 3.01 ENSMUST00000101800.7
Msrb1
methionine sulfoxide reductase B1
chr18_-_62044871 2.96 ENSMUST00000166783.3
ENSMUST00000049378.15
Ablim3
actin binding LIM protein family, member 3
chr7_-_34914675 2.19 ENSMUST00000118444.3
ENSMUST00000122409.8
Lrp3
low density lipoprotein receptor-related protein 3
chr3_+_154302989 1.67 ENSMUST00000140644.8
ENSMUST00000144764.8
ENSMUST00000155232.2
Cryz
crystallin, zeta
chr12_+_89779237 1.62 ENSMUST00000110133.9
ENSMUST00000110130.4
Nrxn3
neurexin III
chr9_+_40180497 1.47 ENSMUST00000049941.12
Scn3b
sodium channel, voltage-gated, type III, beta
chr9_+_40180569 1.45 ENSMUST00000176185.8
Scn3b
sodium channel, voltage-gated, type III, beta
chr9_+_40180726 1.40 ENSMUST00000171835.9
Scn3b
sodium channel, voltage-gated, type III, beta
chr12_+_89779178 1.31 ENSMUST00000238943.2
Nrxn3
neurexin III
chr2_-_80411724 1.25 ENSMUST00000111760.3
Nckap1
NCK-associated protein 1
chr2_-_80411578 1.02 ENSMUST00000028386.12
Nckap1
NCK-associated protein 1
chr5_+_35971697 0.99 ENSMUST00000130233.8
Ablim2
actin-binding LIM protein 2
chr5_-_108777578 0.90 ENSMUST00000046603.15
Gak
cyclin G associated kinase
chr15_-_100320872 0.80 ENSMUST00000138843.8
Slc11a2
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
chr2_+_131048998 0.75 ENSMUST00000153097.3
Ap5s1
adaptor-related protein 5 complex, sigma 1 subunit
chr7_-_97848688 0.65 ENSMUST00000098278.4
B3gnt6
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6 (core 3 synthase)
chr15_-_3333003 0.63 ENSMUST00000165386.2
Ccdc152
coiled-coil domain containing 152
chr1_+_32211792 0.57 ENSMUST00000027226.12
ENSMUST00000189878.2
ENSMUST00000188257.7
ENSMUST00000185666.2
Khdrbs2
KH domain containing, RNA binding, signal transduction associated 2
chrX_+_20714782 0.54 ENSMUST00000001155.11
ENSMUST00000122312.8
ENSMUST00000120356.8
ENSMUST00000122850.2
Araf
Araf proto-oncogene, serine/threonine kinase
chr8_+_105727456 0.53 ENSMUST00000172032.4
Ces2h
carboxylesterase 2H
chr15_+_100321074 0.51 ENSMUST00000148928.2
Gm5475
predicted gene 5475
chr18_+_23886765 0.40 ENSMUST00000115830.8
Mapre2
microtubule-associated protein, RP/EB family, member 2
chr9_+_45341589 0.38 ENSMUST00000239471.2
ENSMUST00000034592.11
ENSMUST00000239429.2
Dscaml1
DS cell adhesion molecule like 1
chr14_+_53279810 0.26 ENSMUST00000198439.5
ENSMUST00000103605.3
Trav8d-2
T cell receptor alpha variable 8D-2
chr15_+_34495441 0.02 ENSMUST00000052290.14
ENSMUST00000079028.6
Pop1
processing of precursor 1, ribonuclease P/MRP family, (S. cerevisiae)

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 6.1 GO:0030091 protein repair(GO:0030091)
0.7 10.6 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.4 4.3 GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.3 2.3 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.3 0.9 GO:0035622 intrahepatic bile duct development(GO:0035622)
0.2 7.4 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.1 2.9 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.1 0.5 GO:0015676 vanadium ion transport(GO:0015676) lead ion transport(GO:0015692)
0.1 1.7 GO:0042178 xenobiotic catabolic process(GO:0042178)
0.0 0.4 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 6.1 GO:0050680 negative regulation of epithelial cell proliferation(GO:0050680)
0.0 3.0 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 10.6 GO:0045179 apical cortex(GO:0045179)
0.2 4.3 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.2 2.3 GO:0031209 SCAR complex(GO:0031209)
0.1 0.5 GO:0070826 paraferritin complex(GO:0070826)
0.0 6.1 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 2.9 GO:0042734 presynaptic membrane(GO:0042734)
0.0 3.0 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.8 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.0 7.1 GO:0015629 actin cytoskeleton(GO:0015629)
0.0 0.4 GO:0035371 microtubule plus-end(GO:0035371)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 10.6 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
1.0 6.1 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.7 6.1 GO:0016892 endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892)
0.5 4.3 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.3 1.7 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.2 7.4 GO:0008392 arachidonic acid epoxygenase activity(GO:0008392)
0.1 0.5 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086) lead ion transmembrane transporter activity(GO:0015094) vanadium ion transmembrane transporter activity(GO:0015100) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.0 2.9 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 2.3 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 0.6 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.9 GO:0030332 cyclin binding(GO:0030332)
0.0 0.5 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.7 GO:0008378 galactosyltransferase activity(GO:0008378)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.3 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 4.3 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.0 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.1 4.3 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 10.6 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.4 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 0.9 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis