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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Zbtb6

Z-value: 1.31

Motif logo

Transcription factors associated with Zbtb6

Gene Symbol Gene ID Gene Info
ENSMUSG00000066798.4 Zbtb6

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Zbtb6mm39_v1_chr2_-_37333109_373332100.209.5e-02Click!

Activity profile of Zbtb6 motif

Sorted Z-values of Zbtb6 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Zbtb6

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr6_-_60806810 8.96 ENSMUST00000163779.8
synuclein, alpha
chr9_-_99599312 8.50 ENSMUST00000112882.9
ENSMUST00000131922.2
claudin 18
chr2_-_126460575 6.61 ENSMUST00000028838.5
histidine decarboxylase
chr15_+_78798116 5.83 ENSMUST00000089378.5
pyridoxal (pyridoxine, vitamin B6) phosphatase
chr11_-_29975916 5.17 ENSMUST00000058902.6
echinoderm microtubule associated protein like 6
chr11_-_102787950 5.15 ENSMUST00000067444.10
glial fibrillary acidic protein
chr1_+_75526225 4.95 ENSMUST00000154101.8
solute carrier family 4 (anion exchanger), member 3
chr15_+_82140224 4.92 ENSMUST00000143238.2
RIKEN cDNA 1500009C09 gene
chr1_+_78488499 4.90 ENSMUST00000012331.7
monoacylglycerol O-acyltransferase 1
chrX_+_135723531 4.55 ENSMUST00000113085.2
proteolipid protein (myelin) 1
chrX_+_135723420 4.34 ENSMUST00000033800.13
proteolipid protein (myelin) 1
chr11_-_65053710 4.32 ENSMUST00000093002.12
ENSMUST00000047463.15
Rho GTPase activating protein 44
chr6_-_113696390 4.31 ENSMUST00000203588.2
ENSMUST00000204163.3
ENSMUST00000203363.3
ghrelin
chr1_+_78488440 4.19 ENSMUST00000152111.2
monoacylglycerol O-acyltransferase 1
chr1_+_134110142 4.06 ENSMUST00000082060.10
ENSMUST00000153856.8
ENSMUST00000133701.8
ENSMUST00000132873.8
chitinase-like 1
chr5_+_73563418 3.97 ENSMUST00000031040.13
ENSMUST00000065543.8
cell wall biogenesis 43 C-terminal homolog
chr6_-_113696809 3.93 ENSMUST00000203770.3
ENSMUST00000064993.8
ghrelin
chr5_-_84565218 3.88 ENSMUST00000113401.4
Eph receptor A5
chr11_-_102787972 3.83 ENSMUST00000077902.5
glial fibrillary acidic protein
chr5_+_30745447 3.79 ENSMUST00000066295.5
potassium channel, subfamily K, member 3
chr14_-_55150547 3.79 ENSMUST00000228495.3
ENSMUST00000228119.3
ENSMUST00000050772.10
ENSMUST00000231305.2
solute carrier family 22 (organic cation transporter), member 17
chr6_+_86005663 3.68 ENSMUST00000204059.3
adducin 2 (beta)
chr7_-_144761806 3.67 ENSMUST00000208788.2
small integral membrane protein 38
chr2_-_113659360 3.55 ENSMUST00000024005.8
secretogranin V
chr15_+_103411461 3.39 ENSMUST00000023132.5
phosphodiesterase 1B, Ca2+-calmodulin dependent
chrX_-_20157966 3.38 ENSMUST00000115393.3
ENSMUST00000072451.11
solute carrier family 9 (sodium/hydrogen exchanger), member 7
chr6_+_29917004 3.37 ENSMUST00000151738.4
ENSMUST00000115224.8
ENSMUST00000046028.12
striatin interacting protein 2
chr17_+_37180437 3.36 ENSMUST00000060524.11
tripartite motif-containing 10
chr5_-_18565353 3.21 ENSMUST00000074694.7
guanine nucleotide binding protein (G protein), alpha inhibiting 1
chr9_+_102988940 3.21 ENSMUST00000189134.2
ENSMUST00000035155.8
RAB6B, member RAS oncogene family
chr15_-_101621332 3.16 ENSMUST00000023709.7
keratin 5
chr16_+_17716480 3.14 ENSMUST00000055374.8
testis-specific serine kinase 2
chr8_-_86091946 3.12 ENSMUST00000034133.14
myosin light chain kinase 3
chr15_+_39061612 2.94 ENSMUST00000082054.12
ENSMUST00000227243.2
ENSMUST00000042917.10
regulating synaptic membrane exocytosis 2
chr17_-_40519480 2.94 ENSMUST00000033585.7
phosphoglycerate kinase 2
chr1_+_134109888 2.94 ENSMUST00000156873.8
chitinase-like 1
chr9_-_62417780 2.84 ENSMUST00000164246.9
coronin, actin binding protein, 2B
chr6_+_86005729 2.79 ENSMUST00000203366.3
adducin 2 (beta)
chr6_+_123239076 2.72 ENSMUST00000032240.4
C-type lectin domain family 4, member d
chr5_+_137551774 2.71 ENSMUST00000136088.8
ENSMUST00000139395.8
actin-like 6B
chr2_+_90948481 2.71 ENSMUST00000137942.8
ENSMUST00000111430.10
ENSMUST00000169776.2
myosin binding protein C, cardiac
chr11_-_115158062 2.65 ENSMUST00000106554.2
glutamate receptor, ionotropic, NMDA2C (epsilon 3)
chr18_+_37637317 2.65 ENSMUST00000052179.8
protocadherin beta 20
chr14_-_55204054 2.60 ENSMUST00000226297.2
myosin, heavy polypeptide 6, cardiac muscle, alpha
chr8_+_106331866 2.55 ENSMUST00000043531.10
RHO family interacting cell polarization regulator 1
chr1_-_75240551 2.49 ENSMUST00000186178.7
ENSMUST00000189769.7
ENSMUST00000027404.12
protein tyrosine phosphatase, receptor type, N
chr5_-_71253107 2.46 ENSMUST00000197284.5
gamma-aminobutyric acid (GABA) A receptor, subunit alpha 2
chr14_-_55204092 2.44 ENSMUST00000081857.14
myosin, heavy polypeptide 6, cardiac muscle, alpha
chrX_-_165992311 2.41 ENSMUST00000112172.4
thymosin, beta 4, X chromosome
chr16_+_17095416 2.40 ENSMUST00000232364.2
transmembrane protein 191C
chr9_-_61883845 2.38 ENSMUST00000113990.2
progestin and adipoQ receptor family member V
chr12_-_116226565 2.37 ENSMUST00000039349.8
dynein 2 intermediate chain 1
chr6_+_124973644 2.35 ENSMUST00000032479.11
PILR alpha associated neural protein
chr17_-_46798566 2.34 ENSMUST00000047034.9
tau tubulin kinase 1
chr13_+_110531571 2.31 ENSMUST00000022212.9
polo like kinase 2
chr11_-_42073737 2.31 ENSMUST00000206085.2
ENSMUST00000020707.12
ENSMUST00000132971.3
gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1
chr6_+_124973752 2.31 ENSMUST00000162000.4
PILR alpha associated neural protein
chr8_-_86091970 2.30 ENSMUST00000121972.8
myosin light chain kinase 3
chr8_-_23295603 2.26 ENSMUST00000163739.3
ENSMUST00000210656.2
adaptor-related protein complex 3, mu 2 subunit
chr8_+_75820240 2.23 ENSMUST00000005548.8
heme oxygenase 1
chr17_-_25394445 2.21 ENSMUST00000224277.2
proline and glutamate rich with coiled coil 1
chr2_+_177834868 2.19 ENSMUST00000103065.2
phosphatase and actin regulator 3
chr7_+_118454957 2.18 ENSMUST00000208658.2
ENSMUST00000098087.9
ENSMUST00000106547.2
IQ motif containing K
chr3_+_92864693 2.17 ENSMUST00000059053.11
late cornified envelope 3D
chr14_+_56640038 2.17 ENSMUST00000095793.3
ENSMUST00000223627.2
ring finger protein 17
chr9_+_54606832 2.15 ENSMUST00000070070.8
DnaJ heat shock protein family (Hsp40) member A4
chr9_+_22322802 2.13 ENSMUST00000058868.9
RIKEN cDNA 9530077C05 gene
chr9_+_54606144 2.13 ENSMUST00000120452.8
DnaJ heat shock protein family (Hsp40) member A4
chr17_-_35069136 2.12 ENSMUST00000046022.16
superkiller viralicidic activity 2-like (S. cerevisiae)
chr16_+_17712061 2.07 ENSMUST00000046937.4
testis-specific serine kinase 1
chr2_+_21372338 2.06 ENSMUST00000055946.8
G protein-coupled receptor 158
chr14_-_55204023 2.05 ENSMUST00000124930.8
myosin, heavy polypeptide 6, cardiac muscle, alpha
chr14_-_55204383 2.04 ENSMUST00000111456.2
myosin, heavy polypeptide 6, cardiac muscle, alpha
chr9_+_54606798 2.03 ENSMUST00000154690.8
DnaJ heat shock protein family (Hsp40) member A4
chr13_+_55517545 2.03 ENSMUST00000063771.14
regulator of G-protein signaling 14
chr7_-_140402037 2.01 ENSMUST00000106052.2
ENSMUST00000080651.13
zinc finger protein 941
chr14_-_79718890 2.00 ENSMUST00000022601.7
WW domain binding protein 4
chr14_+_26959975 1.89 ENSMUST00000049206.6
Rho guanine nucleotide exchange factor (GEF) 3
chr7_-_30738471 1.88 ENSMUST00000162250.8
FXYD domain-containing ion transport regulator 5
chr5_-_31359559 1.88 ENSMUST00000202929.2
ENSMUST00000201231.2
ENSMUST00000114590.8
zinc finger protein 513
chr7_+_3439144 1.85 ENSMUST00000182222.8
calcium channel, voltage-dependent, gamma subunit 8
chr9_+_58395850 1.83 ENSMUST00000085658.5
inhibitory synaptic factor 1
chr5_+_137551790 1.83 ENSMUST00000136565.8
ENSMUST00000149292.8
ENSMUST00000125489.2
actin-like 6B
chr3_-_92594516 1.82 ENSMUST00000029524.4
late cornified envelope 1D
chr19_-_46561532 1.80 ENSMUST00000026009.10
ENSMUST00000236255.2
ADP-ribosylation factor-like 3
chr4_-_140780972 1.78 ENSMUST00000040222.14
ciliary rootlet coiled-coil, rootletin
chr4_-_140781015 1.76 ENSMUST00000102491.10
ciliary rootlet coiled-coil, rootletin
chr8_-_106434565 1.75 ENSMUST00000013299.11
enkurin domain containing 1
chrX_+_49930311 1.72 ENSMUST00000114887.9
serine/threonine kinase 26
chr17_+_25946644 1.69 ENSMUST00000237183.2
ENSMUST00000237785.2
ENSMUST00000047273.3
RNA pseudouridylate synthase domain containing 1
chr11_-_72252663 1.65 ENSMUST00000108503.9
tektin 1
chr4_+_124880223 1.64 ENSMUST00000030687.8
R-spondin 1
chr3_-_100396635 1.62 ENSMUST00000061455.9
terminal nucleotidyltransferase 5C
chr9_-_21982637 1.57 ENSMUST00000179605.9
ENSMUST00000043922.7
zinc finger protein 653
chr4_-_87724512 1.56 ENSMUST00000148059.2
myeloid/lymphoid or mixed-lineage leukemia; translocated to, 3
chr10_+_21469039 1.56 ENSMUST00000057341.6
RIKEN cDNA 1700020N01 gene
chr14_+_55131568 1.56 ENSMUST00000116476.9
ENSMUST00000022808.14
ENSMUST00000150975.8
poly(A) binding protein, nuclear 1
chr18_+_36098090 1.53 ENSMUST00000176873.8
ENSMUST00000177432.8
ENSMUST00000175734.2
pleckstrin and Sec7 domain containing 2
chr4_-_87724533 1.52 ENSMUST00000126353.8
ENSMUST00000149357.8
myeloid/lymphoid or mixed-lineage leukemia; translocated to, 3
chr11_+_3939924 1.50 ENSMUST00000109981.2
galactose-3-O-sulfotransferase 1
chr15_+_102234825 1.49 ENSMUST00000165671.8
ENSMUST00000165717.4
prefoldin 5
chr11_+_114656189 1.48 ENSMUST00000138804.8
ENSMUST00000084368.12
kinesin family member 19A
chr15_-_99355623 1.47 ENSMUST00000023747.14
NCK-associated protein 5-like
chr4_+_107659361 1.47 ENSMUST00000106731.4
low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
chr5_+_135835713 1.45 ENSMUST00000126232.8
serine/arginine repetitive matrix 3
chr10_-_116808514 1.44 ENSMUST00000092165.5
predicted gene 10271
chr15_-_73114855 1.43 ENSMUST00000227686.2
PTK2 protein tyrosine kinase 2
chr19_-_5507532 1.43 ENSMUST00000236881.2
coiled-coil domain containing 85B
chr11_-_102837514 1.43 ENSMUST00000057849.6
complement component 1, q subcomponent-like 1
chr7_-_24145107 1.42 ENSMUST00000205776.2
immunity-related GTPase family, cinema 1
chr7_+_28488380 1.41 ENSMUST00000209035.2
ENSMUST00000059857.8
Ras and Rab interactor-like
chr11_-_113956996 1.41 ENSMUST00000041627.14
sidekick cell adhesion molecule 2
chr6_+_124974009 1.40 ENSMUST00000159391.8
PILR alpha associated neural protein
chr1_-_78488795 1.38 ENSMUST00000170511.3
cDNA sequence BC035947
chr3_-_95214443 1.37 ENSMUST00000015846.9
annexin A9
chr16_-_18052937 1.37 ENSMUST00000076957.7
zinc finger, DHHC domain containing 8
chr13_+_12580772 1.36 ENSMUST00000220811.2
endoplasmic reticulum oxidoreductase 1 beta
chr15_+_102234551 1.34 ENSMUST00000166658.8
ENSMUST00000062492.11
prefoldin 5
chr7_+_105053775 1.34 ENSMUST00000033187.6
ENSMUST00000210344.2
cyclic nucleotide gated channel alpha 4
chr13_-_59879548 1.34 ENSMUST00000052978.6
spermatogenesis associated 31 subfamily D, member 1D
chr1_+_133965228 1.32 ENSMUST00000162779.2
fibromodulin
chr13_-_26954110 1.30 ENSMUST00000055915.6
HDGF like 1
chr4_-_42665763 1.29 ENSMUST00000238770.2
interleukin 11 receptor, alpha chain 2
chr7_-_24134919 1.29 ENSMUST00000080594.8
immunity-related GTPase family, cinema 1
chr4_-_42168603 1.27 ENSMUST00000098121.4
predicted gene 13305
chrX_+_47001264 1.26 ENSMUST00000001202.15
ENSMUST00000115020.8
OCRL, inositol polyphosphate-5-phosphatase
chr18_+_37580692 1.22 ENSMUST00000052387.5
protocadherin beta 14
chr14_-_52258158 1.22 ENSMUST00000228580.2
ENSMUST00000226554.2
ENSMUST00000067549.15
zinc finger protein 219
chr11_-_51153767 1.21 ENSMUST00000065950.10
cDNA sequence BC049762
chr3_-_95799242 1.21 ENSMUST00000171519.2
ENSMUST00000036360.13
ENSMUST00000090476.10
cDNA sequence BC028528
chr2_+_144441817 1.21 ENSMUST00000028917.7
D-tyrosyl-tRNA deacylase 1
chr7_-_44785709 1.18 ENSMUST00000211429.2
FMS-like tyrosine kinase 3 ligand
chr12_+_111373243 1.17 ENSMUST00000150384.3
LBH domain containing 2
chr17_-_56607250 1.17 ENSMUST00000233911.2
arrestin domain containing 5
chr2_-_164670452 1.16 ENSMUST00000017911.4
spermatogenesis associated 25
chr4_+_137720326 1.14 ENSMUST00000139759.8
ENSMUST00000058133.10
ENSMUST00000105830.9
ENSMUST00000084215.12
eukaryotic translation initiation factor 4 gamma, 3
chr16_-_44979013 1.13 ENSMUST00000023344.10
solute carrier family 35, member A5
chr8_+_94899292 1.13 ENSMUST00000034214.8
ENSMUST00000212806.2
metallothionein 2
chr14_+_56905698 1.12 ENSMUST00000116468.2
M-phase phosphoprotein 8
chr16_-_38370535 1.12 ENSMUST00000036210.7
protein O-glucosyltransferase 1
chr18_+_37575553 1.10 ENSMUST00000056915.3
protocadherin beta 13
chr9_+_22322875 1.10 ENSMUST00000214436.2
RIKEN cDNA 9530077C05 gene
chr15_+_102234589 1.09 ENSMUST00000170627.8
prefoldin 5
chr6_+_113600920 1.09 ENSMUST00000035673.8
von Hippel-Lindau tumor suppressor
chr4_+_117692583 1.08 ENSMUST00000169885.8
solute carrier family 6 (neurotransmitter transporter, glycine), member 9
chr15_+_99023775 1.06 ENSMUST00000230628.2
ENSMUST00000229073.2
ENSMUST00000229147.2
spermatogenesis associated, serine-rich 2
chr18_+_37488174 1.05 ENSMUST00000192867.2
ENSMUST00000051163.3
protocadherin beta 8
chr15_+_58004793 1.03 ENSMUST00000227142.2
ENSMUST00000226955.2
WDYHV motif containing 1
chr5_-_72325482 1.01 ENSMUST00000196241.2
ENSMUST00000013693.11
COMM domain containing 8
chr17_+_35069347 1.01 ENSMUST00000097343.11
ENSMUST00000173357.8
ENSMUST00000173065.8
ENSMUST00000165953.3
negative elongation factor complex member E, Rdbp
chr7_+_140427729 1.00 ENSMUST00000106049.2
outer dense fiber of sperm tails 3
chr6_+_113508636 1.00 ENSMUST00000036340.12
ENSMUST00000204827.3
Fanconi anemia, complementation group D2
chr10_+_70080913 0.99 ENSMUST00000046807.7
solute carrier family 16 (monocarboxylic acid transporters), member 9
chr16_-_56748424 0.98 ENSMUST00000210579.2
leukemia NUP98 fusion partner 1
chr2_+_52747855 0.97 ENSMUST00000155586.9
ENSMUST00000090952.11
ENSMUST00000127122.9
ENSMUST00000049483.14
ENSMUST00000050719.13
formin-like 2
chr11_-_51153870 0.97 ENSMUST00000054226.3
cDNA sequence BC049762
chr6_-_112466780 0.96 ENSMUST00000053306.8
oxytocin receptor
chr8_-_13940234 0.94 ENSMUST00000033839.9
coordinator of PRMT5, differentiation stimulator
chr15_+_103411689 0.94 ENSMUST00000226493.2
phosphodiesterase 1B, Ca2+-calmodulin dependent
chr7_+_140427711 0.93 ENSMUST00000026555.12
outer dense fiber of sperm tails 3
chr13_+_12580743 0.92 ENSMUST00000221560.2
ENSMUST00000071973.8
endoplasmic reticulum oxidoreductase 1 beta
chr15_+_58004753 0.90 ENSMUST00000067563.9
WDYHV motif containing 1
chr18_-_15196612 0.88 ENSMUST00000168989.9
potassium channel tetramerisation domain containing 1
chrX_-_151820545 0.88 ENSMUST00000051484.5
MAGE family member H1
chr15_-_48655329 0.87 ENSMUST00000160658.8
ENSMUST00000100670.10
ENSMUST00000162830.8
CUB and Sushi multiple domains 3
chr10_+_19588318 0.87 ENSMUST00000020185.5
interleukin 20 receptor, alpha
chr10_-_128505096 0.87 ENSMUST00000238610.2
ENSMUST00000238712.2
IKAROS family zinc finger 4
chr14_+_55132061 0.86 ENSMUST00000172557.2
poly(A) binding protein, nuclear 1
chr9_+_66257747 0.83 ENSMUST00000042824.13
HECT and RLD domain containing E3 ubiquitin protein ligase family member 1
chr7_-_44785815 0.83 ENSMUST00000146760.7
FMS-like tyrosine kinase 3 ligand
chr12_-_69629758 0.83 ENSMUST00000058639.11
valosin containing protein lysine (K) methyltransferase
chr9_+_108660989 0.82 ENSMUST00000192307.6
ENSMUST00000193560.6
ENSMUST00000194875.6
inositol hexaphosphate kinase 2
chr11_+_76563281 0.81 ENSMUST00000056184.2
basic helix-loop-helix family, member a9
chr16_-_44978816 0.79 ENSMUST00000181750.2
solute carrier family 35, member A5
chr15_+_102234802 0.79 ENSMUST00000169637.8
prefoldin 5
chr4_+_136013372 0.79 ENSMUST00000069195.5
ENSMUST00000130658.2
zinc finger protein 46
chr11_-_83320281 0.78 ENSMUST00000052521.9
growth arrest-specific 2 like 2
chr14_+_55132030 0.78 ENSMUST00000141446.8
ENSMUST00000139985.8
poly(A) binding protein, nuclear 1
chr13_-_98773862 0.78 ENSMUST00000050389.5
transmembrane protein 174
chr7_-_103792462 0.76 ENSMUST00000057254.6
ubiquilin 3
chr1_-_135358228 0.76 ENSMUST00000041023.14
importin 9
chr16_-_44978929 0.74 ENSMUST00000181177.2
solute carrier family 35, member A5
chr3_-_129548954 0.72 ENSMUST00000029653.7
epidermal growth factor
chr6_-_139478919 0.72 ENSMUST00000170650.3
RERG/RAS-like
chr19_-_23251179 0.72 ENSMUST00000087556.7
ENSMUST00000223934.2
structural maintenance of chromosomes 5
chr8_-_95564881 0.71 ENSMUST00000034233.15
ENSMUST00000162538.9
cytokine induced apoptosis inhibitor 1
chr17_-_25652750 0.71 ENSMUST00000159610.8
ENSMUST00000159048.8
ENSMUST00000078496.12
calcium channel, voltage-dependent, T type, alpha 1H subunit
chr11_-_17903861 0.71 ENSMUST00000076661.7
Ewing tumor-associated antigen 1
chr11_+_51153941 0.70 ENSMUST00000093132.13
ENSMUST00000109113.8
CDC like kinase 4
chr3_-_107424637 0.70 ENSMUST00000166892.2
solute carrier family 6 (neurotransmitter transporter), member 17
chr18_+_37646674 0.69 ENSMUST00000061405.6
protocadherin beta 21
chr2_+_32340459 0.68 ENSMUST00000048431.3
nuclear apoptosis inducing factor 1
chr17_-_56607286 0.66 ENSMUST00000097303.3
arrestin domain containing 5
chr15_+_99024394 0.66 ENSMUST00000063517.6
spermatogenesis associated, serine-rich 2
chr10_-_120815232 0.64 ENSMUST00000119944.8
ENSMUST00000119093.2
LEM domain containing 3
chrX_-_52328963 0.60 ENSMUST00000074861.9
placental specific protein 1
chr16_-_44978986 0.59 ENSMUST00000180636.8
solute carrier family 35, member A5
chr7_+_79939747 0.58 ENSMUST00000205864.2
vacuolar protein sorting 33B
chr8_+_120339440 0.58 ENSMUST00000098361.4
adenosine deaminase domain containing 2
chr17_+_29171386 0.58 ENSMUST00000118762.9
ENSMUST00000057174.16
ENSMUST00000232874.2
ENSMUST00000232772.2
ENSMUST00000233334.2
ENSMUST00000150858.2
ENSMUST00000233064.2
potassium channel tetramerisation domain containing 20

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.0 9.0 GO:2000295 regulation of hydrogen peroxide catabolic process(GO:2000295)
2.3 9.1 GO:0007522 visceral muscle development(GO:0007522)
2.1 8.2 GO:1990768 regulation of gastric mucosal blood circulation(GO:1904344) positive regulation of gastric mucosal blood circulation(GO:1904346) gastric mucosal blood circulation(GO:1990768) negative regulation of energy homeostasis(GO:2000506)
1.9 5.8 GO:0042822 pyridoxal phosphate metabolic process(GO:0042822)
1.5 9.1 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
1.5 9.0 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
1.3 6.6 GO:0001692 histamine metabolic process(GO:0001692) histidine catabolic process(GO:0006548)
1.3 3.8 GO:0015688 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
1.2 8.5 GO:2001205 negative regulation of osteoclast development(GO:2001205)
0.9 5.4 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.9 4.3 GO:0098886 modification of dendritic spine(GO:0098886)
0.8 3.2 GO:1904247 positive regulation of polynucleotide adenylyltransferase activity(GO:1904247)
0.7 2.2 GO:0006788 heme oxidation(GO:0006788)
0.6 2.5 GO:2001107 negative regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001107)
0.6 3.5 GO:1903566 ciliary basal body organization(GO:0032053) positive regulation of protein localization to cilium(GO:1903566)
0.5 2.5 GO:0090290 positive regulation of osteoclast proliferation(GO:0090290)
0.4 8.9 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.4 7.1 GO:1904322 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.4 6.3 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.4 1.1 GO:1902071 regulation of hypoxia-inducible factor-1alpha signaling pathway(GO:1902071)
0.4 1.1 GO:0061536 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.3 2.7 GO:0038094 Fc-gamma receptor signaling pathway(GO:0038094)
0.3 2.7 GO:0033058 directional locomotion(GO:0033058)
0.3 4.3 GO:0036005 response to macrophage colony-stimulating factor(GO:0036005) cellular response to macrophage colony-stimulating factor stimulus(GO:0036006)
0.3 7.0 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.3 1.4 GO:0099558 maintenance of synapse structure(GO:0099558)
0.3 3.4 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.2 1.4 GO:0007172 signal complex assembly(GO:0007172)
0.2 0.7 GO:0036500 ATF6-mediated unfolded protein response(GO:0036500)
0.2 2.9 GO:0098814 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.2 2.7 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.2 2.1 GO:0034427 nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'(GO:0034427)
0.2 4.1 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.2 3.8 GO:0030322 stabilization of membrane potential(GO:0030322)
0.2 1.1 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.2 1.7 GO:0031119 rRNA pseudouridine synthesis(GO:0031118) tRNA pseudouridine synthesis(GO:0031119)
0.2 2.0 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.2 1.5 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.2 1.5 GO:0038026 reelin-mediated signaling pathway(GO:0038026)
0.2 1.0 GO:0001992 regulation of systemic arterial blood pressure by vasopressin(GO:0001992)
0.2 6.5 GO:0050901 leukocyte tethering or rolling(GO:0050901)
0.2 1.2 GO:0006450 regulation of translational fidelity(GO:0006450)
0.1 1.6 GO:2000052 positive regulation of non-canonical Wnt signaling pathway(GO:2000052)
0.1 2.5 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.1 0.7 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.1 0.6 GO:2000049 positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
0.1 1.1 GO:0010273 detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169)
0.1 2.3 GO:0032486 Rap protein signal transduction(GO:0032486)
0.1 0.9 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.1 3.4 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.1 2.4 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.1 3.5 GO:0016486 peptide hormone processing(GO:0016486)
0.1 0.7 GO:0034184 positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184)
0.1 0.4 GO:1900158 negative regulation of bone mineralization involved in bone maturation(GO:1900158)
0.1 1.1 GO:0060903 positive regulation of meiosis I(GO:0060903)
0.1 0.3 GO:0070318 enucleate erythrocyte development(GO:0048822) positive regulation of G0 to G1 transition(GO:0070318)
0.1 2.0 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.1 0.5 GO:0061622 glycolytic process through glucose-1-phosphate(GO:0061622)
0.1 0.6 GO:0090214 spongiotrophoblast layer developmental growth(GO:0090214)
0.1 2.3 GO:0071420 cellular response to histamine(GO:0071420)
0.1 1.0 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.1 1.1 GO:0015824 proline transport(GO:0015824)
0.1 1.0 GO:1900364 negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244) negative regulation of mRNA polyadenylation(GO:1900364)
0.1 2.3 GO:0099517 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.1 0.6 GO:0070889 platelet alpha granule organization(GO:0070889)
0.1 1.6 GO:0060294 cilium movement involved in cell motility(GO:0060294)
0.1 0.5 GO:0016266 O-glycan processing(GO:0016266)
0.1 4.0 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.1 0.6 GO:0097240 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.1 0.7 GO:0034651 cortisol biosynthetic process(GO:0034651)
0.1 0.8 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.1 2.9 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.1 0.2 GO:0001579 medium-chain fatty acid transport(GO:0001579)
0.1 4.0 GO:0018149 peptide cross-linking(GO:0018149)
0.1 1.7 GO:0030033 microvillus assembly(GO:0030033)
0.0 3.7 GO:0007019 microtubule depolymerization(GO:0007019)
0.0 0.6 GO:0035655 interleukin-18-mediated signaling pathway(GO:0035655)
0.0 2.9 GO:0030317 sperm motility(GO:0030317)
0.0 1.0 GO:0046415 urate metabolic process(GO:0046415)
0.0 0.8 GO:0021702 cerebellar Purkinje cell differentiation(GO:0021702)
0.0 4.8 GO:0051453 regulation of intracellular pH(GO:0051453)
0.0 1.4 GO:0018345 protein palmitoylation(GO:0018345)
0.0 1.3 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 1.3 GO:0051290 protein heterotetramerization(GO:0051290)
0.0 1.5 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.8 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.0 1.8 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.0 1.0 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 7.4 GO:0007286 spermatid development(GO:0007286)
0.0 1.1 GO:0044030 regulation of DNA methylation(GO:0044030)
0.0 7.4 GO:0007416 synapse assembly(GO:0007416)
0.0 1.3 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 5.0 GO:0006333 chromatin assembly or disassembly(GO:0006333)
0.0 0.3 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.5 GO:0010825 positive regulation of centrosome duplication(GO:0010825)
0.0 2.0 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.0 0.4 GO:0070475 rRNA base methylation(GO:0070475)
0.0 4.7 GO:0090090 negative regulation of canonical Wnt signaling pathway(GO:0090090)
0.0 0.7 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 0.7 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.0 1.8 GO:0042073 intraciliary transport(GO:0042073)
0.0 0.3 GO:1904424 regulation of GTP binding(GO:1904424)
0.0 0.1 GO:0010836 negative regulation of protein ADP-ribosylation(GO:0010836)
0.0 0.8 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 0.1 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 5.5 GO:0008360 regulation of cell shape(GO:0008360)
0.0 0.3 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0 0.4 GO:0006661 phosphatidylinositol biosynthetic process(GO:0006661)
0.0 1.9 GO:2000649 regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.0 0.3 GO:0046520 sphingoid biosynthetic process(GO:0046520)
0.0 0.4 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.0 0.9 GO:0045124 regulation of bone resorption(GO:0045124)
0.0 0.6 GO:0071158 positive regulation of cell cycle arrest(GO:0071158)
0.0 0.1 GO:1904378 maintenance of unfolded protein(GO:0036506) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
0.0 0.7 GO:1902108 regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902108)
0.0 1.2 GO:0048477 oogenesis(GO:0048477)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 9.0 GO:0031092 platelet alpha granule membrane(GO:0031092)
1.1 9.0 GO:0098574 cytoplasmic side of lysosomal membrane(GO:0098574)
0.9 2.7 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.7 2.1 GO:0055087 Ski complex(GO:0055087)
0.4 4.7 GO:0016272 prefoldin complex(GO:0016272)
0.4 6.5 GO:0008290 F-actin capping protein complex(GO:0008290)
0.4 9.1 GO:0005859 muscle myosin complex(GO:0005859)
0.3 1.4 GO:0044301 climbing fiber(GO:0044301)
0.3 1.0 GO:0032021 NELF complex(GO:0032021)
0.2 5.8 GO:0070938 contractile ring(GO:0070938)
0.2 1.0 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.2 0.7 GO:0035061 interchromatin granule(GO:0035061)
0.2 4.5 GO:0016514 SWI/SNF complex(GO:0016514)
0.2 1.3 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.2 4.3 GO:1902711 GABA-A receptor complex(GO:1902711)
0.2 3.2 GO:0042405 nuclear inclusion body(GO:0042405)
0.1 1.9 GO:0001520 outer dense fiber(GO:0001520)
0.1 3.5 GO:0035253 ciliary rootlet(GO:0035253)
0.1 2.7 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 0.5 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.1 2.9 GO:0035686 sperm fibrous sheath(GO:0035686)
0.1 2.2 GO:1904115 axon cytoplasm(GO:1904115)
0.1 1.1 GO:0030891 VCB complex(GO:0030891)
0.1 1.1 GO:0000788 nuclear nucleosome(GO:0000788)
0.1 5.3 GO:0048786 presynaptic active zone(GO:0048786)
0.1 2.5 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.1 3.2 GO:0045095 keratin filament(GO:0045095)
0.1 3.4 GO:0055038 recycling endosome membrane(GO:0055038)
0.1 4.0 GO:0001533 cornified envelope(GO:0001533)
0.1 1.5 GO:0035371 microtubule plus-end(GO:0035371)
0.1 0.6 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.1 3.1 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 3.2 GO:0099738 cell cortex region(GO:0099738)
0.0 3.6 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 5.9 GO:0005814 centriole(GO:0005814)
0.0 0.3 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.6 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 1.8 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.3 GO:0000322 storage vacuole(GO:0000322)
0.0 3.9 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 0.3 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750)
0.0 0.6 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0 4.7 GO:0005901 caveola(GO:0005901)
0.0 1.5 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 7.9 GO:0043209 myelin sheath(GO:0043209)
0.0 11.1 GO:0005874 microtubule(GO:0005874)
0.0 0.4 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 1.1 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.6 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.1 GO:0070522 ERCC4-ERCC1 complex(GO:0070522)
0.0 0.2 GO:0031209 SCAR complex(GO:0031209)
0.0 1.3 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 6.7 GO:0030141 secretory granule(GO:0030141)
0.0 5.3 GO:0000139 Golgi membrane(GO:0000139)
0.0 1.1 GO:0014704 intercalated disc(GO:0014704)
0.0 0.7 GO:0043596 nuclear replication fork(GO:0043596)
0.0 0.1 GO:0072379 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0 0.3 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 7.7 GO:0005912 adherens junction(GO:0005912)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.7 8.2 GO:0031768 ghrelin receptor binding(GO:0031768)
1.5 9.1 GO:0003846 2-acylglycerol O-acyltransferase activity(GO:0003846) diacylglycerol O-acyltransferase activity(GO:0004144)
1.5 5.8 GO:0033883 pyridoxal phosphatase activity(GO:0033883)
1.3 9.1 GO:0030899 calcium-dependent ATPase activity(GO:0030899)
0.8 9.0 GO:1903136 cuprous ion binding(GO:1903136)
0.7 2.2 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.7 2.2 GO:0070773 protein-N-terminal glutamine amidohydrolase activity(GO:0070773)
0.6 5.4 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.6 8.9 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.6 2.9 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.6 7.0 GO:0008061 chitin binding(GO:0008061)
0.5 4.8 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.4 3.2 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.4 4.3 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.4 3.9 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.4 1.5 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733)
0.4 1.1 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.4 1.5 GO:0038025 reelin receptor activity(GO:0038025)
0.3 3.4 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.3 0.9 GO:0042015 interleukin-20 binding(GO:0042015)
0.2 4.9 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.2 1.3 GO:0005223 intracellular cAMP activated cation channel activity(GO:0005222) intracellular cGMP activated cation channel activity(GO:0005223)
0.2 0.8 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.2 2.7 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.2 1.3 GO:0047045 testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.2 3.8 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.2 0.7 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.2 0.5 GO:0035252 UDP-xylosyltransferase activity(GO:0035252)
0.1 0.6 GO:0042008 interleukin-18 receptor activity(GO:0042008)
0.1 0.8 GO:0052724 inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.1 2.3 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.1 2.7 GO:0032036 myosin heavy chain binding(GO:0032036) structural molecule activity conferring elasticity(GO:0097493)
0.1 0.5 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.1 3.3 GO:0005351 sugar:proton symporter activity(GO:0005351)
0.1 0.4 GO:0008988 rRNA (adenine-N6-)-methyltransferase activity(GO:0008988)
0.1 6.6 GO:0016831 carboxy-lyase activity(GO:0016831)
0.1 14.6 GO:0051082 unfolded protein binding(GO:0051082)
0.1 3.2 GO:0031489 myosin V binding(GO:0031489)
0.1 1.7 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.1 1.0 GO:0005000 vasopressin receptor activity(GO:0005000)
0.1 3.2 GO:0008143 poly(A) binding(GO:0008143)
0.1 0.5 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.1 9.0 GO:0030507 spectrin binding(GO:0030507)
0.1 1.3 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439)
0.1 1.7 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.1 0.3 GO:0036033 mediator complex binding(GO:0036033)
0.1 2.0 GO:0032794 GTPase activating protein binding(GO:0032794)
0.1 1.1 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.1 9.0 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 0.3 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1 0.4 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.1 1.0 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.1 2.5 GO:0071889 14-3-3 protein binding(GO:0071889)
0.1 2.4 GO:0003785 actin monomer binding(GO:0003785)
0.1 1.5 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1 3.5 GO:0019894 kinesin binding(GO:0019894)
0.1 2.0 GO:0070064 proline-rich region binding(GO:0070064)
0.0 4.3 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 2.1 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.4 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0 1.4 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.7 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.0 1.0 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 1.4 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.6 GO:0004000 adenosine deaminase activity(GO:0004000)
0.0 1.5 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 1.8 GO:0019003 GDP binding(GO:0019003)
0.0 0.7 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.0 0.7 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.4 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.0 2.1 GO:0003724 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004)
0.0 1.8 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.3 GO:1901612 cardiolipin binding(GO:1901612)
0.0 1.4 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 1.9 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.1 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.0 0.1 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 2.7 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.7 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.3 GO:0031386 protein tag(GO:0031386)
0.0 0.4 GO:0031005 filamin binding(GO:0031005)
0.0 5.2 GO:0000287 magnesium ion binding(GO:0000287)
0.0 1.9 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 2.1 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 2.9 GO:0044325 ion channel binding(GO:0044325)
0.0 0.7 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.7 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 1.0 GO:0017048 Rho GTPase binding(GO:0017048)
0.0 0.2 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 2.8 GO:0051015 actin filament binding(GO:0051015)
0.0 0.7 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.4 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.2 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 0.1 GO:0030375 thyroid hormone receptor coactivator activity(GO:0030375)
0.0 0.6 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.0 1.1 GO:0035064 methylated histone binding(GO:0035064)
0.0 3.4 GO:0008017 microtubule binding(GO:0008017)
0.0 0.9 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.0 0.8 GO:0016279 lysine N-methyltransferase activity(GO:0016278) protein-lysine N-methyltransferase activity(GO:0016279)
0.0 0.7 GO:0003743 translation initiation factor activity(GO:0003743)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.2 PID S1P S1P4 PATHWAY S1P4 pathway
0.1 9.0 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.1 3.9 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 1.6 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 1.4 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 2.2 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 1.1 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 3.2 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.7 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 4.7 PID P73PATHWAY p73 transcription factor network
0.0 1.4 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 1.0 PID ATM PATHWAY ATM pathway
0.0 1.3 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 5.5 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.4 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 1.9 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.6 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.6 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway
0.0 0.9 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 0.9 PID TGFBR PATHWAY TGF-beta receptor signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 8.2 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.3 9.0 REACTOME AMYLOIDS Genes involved in Amyloids
0.2 3.8 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.2 4.8 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.2 3.2 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.1 3.2 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.1 4.7 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.1 4.3 REACTOME CA DEPENDENT EVENTS Genes involved in Ca-dependent events
0.1 9.0 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.1 6.6 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 2.7 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.1 1.3 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.1 2.2 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.1 1.3 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.1 1.0 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.1 1.4 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.1 1.4 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 1.1 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.1 1.3 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.1 1.8 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.1 0.7 REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA Genes involved in Activation of Chaperones by ATF6-alpha
0.1 1.0 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 1.5 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 1.5 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 3.1 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 5.3 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.5 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 1.1 REACTOME PRE NOTCH EXPRESSION AND PROCESSING Genes involved in Pre-NOTCH Expression and Processing
0.0 1.1 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.4 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.5 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 1.1 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 1.9 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.7 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.3 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA