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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Zbtb7c

Z-value: 1.37

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Transcription factors associated with Zbtb7c

Gene Symbol Gene ID Gene Info
Zbtb7c
ENSMUSG00000044646.16 Zbtb7c

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Zbtb7cmm39_v1_chr18_+_75953244_759533080.113.6e-01Click!

Activity profile of Zbtb7c motif

Sorted Z-values of Zbtb7c motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Zbtb7c

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr10_-_127099183 34.39 ENSMUST00000099172.5
Kif5a
kinesin family member 5A
chr10_-_127098932 32.65 ENSMUST00000217895.2
Kif5a
kinesin family member 5A
chr18_+_33072194 16.23 ENSMUST00000042868.6
Camk4
calcium/calmodulin-dependent protein kinase IV
chr7_-_57159119 11.23 ENSMUST00000206382.2
Gabra5
gamma-aminobutyric acid (GABA) A receptor, subunit alpha 5
chr12_-_109034099 10.27 ENSMUST00000190647.3
Begain
brain-enriched guanylate kinase-associated
chr11_-_100084072 9.96 ENSMUST00000059707.3
Krt9
keratin 9
chr14_+_111912529 9.79 ENSMUST00000042767.9
Slitrk5
SLIT and NTRK-like family, member 5
chr19_-_46306506 8.91 ENSMUST00000224556.2
Psd
pleckstrin and Sec7 domain containing
chr12_-_4088905 8.39 ENSMUST00000111178.2
Efr3b
EFR3 homolog B
chr6_+_135174975 8.33 ENSMUST00000111915.8
ENSMUST00000111916.2
Fam234b
family with sequence similarity 234, member B
chrX_+_134739783 8.06 ENSMUST00000173804.8
ENSMUST00000113136.8
Gprasp2
G protein-coupled receptor associated sorting protein 2
chr15_-_101759212 7.78 ENSMUST00000023790.5
Krt1
keratin 1
chr16_+_11802445 7.44 ENSMUST00000170672.9
ENSMUST00000023138.8
Shisa9
shisa family member 9
chr7_+_44091822 7.43 ENSMUST00000058667.15
Lrrc4b
leucine rich repeat containing 4B
chr7_+_57240250 7.29 ENSMUST00000196198.5
Gabrb3
gamma-aminobutyric acid (GABA) A receptor, subunit beta 3
chr2_+_157401998 6.71 ENSMUST00000153739.9
ENSMUST00000173595.2
ENSMUST00000109526.2
ENSMUST00000173839.2
ENSMUST00000173041.8
ENSMUST00000173793.8
ENSMUST00000172487.2
ENSMUST00000088484.6
Nnat
neuronatin
chr16_-_48814437 6.67 ENSMUST00000121869.8
Dzip3
DAZ interacting protein 3, zinc finger
chr1_+_34840785 6.62 ENSMUST00000047664.16
ENSMUST00000211073.2
Arhgef4
SMIM39
Rho guanine nucleotide exchange factor (GEF) 4
novel protein
chr6_+_135175031 6.44 ENSMUST00000130612.2
Fam234b
family with sequence similarity 234, member B
chr11_+_53410697 6.28 ENSMUST00000120878.9
ENSMUST00000147912.2
Septin8
septin 8
chr16_-_48814294 6.23 ENSMUST00000114516.8
Dzip3
DAZ interacting protein 3, zinc finger
chr15_+_78783867 6.21 ENSMUST00000134703.8
ENSMUST00000061239.14
ENSMUST00000109698.9
Gm49510
Sh3bp1
predicted gene, 49510
SH3-domain binding protein 1
chr11_+_101066867 6.17 ENSMUST00000103109.4
Cntnap1
contactin associated protein-like 1
chr1_-_162305573 5.92 ENSMUST00000086074.12
ENSMUST00000070330.14
Dnm3
dynamin 3
chr7_-_19043955 5.90 ENSMUST00000207334.2
ENSMUST00000208505.2
ENSMUST00000207716.2
ENSMUST00000208326.2
ENSMUST00000003640.4
Fosb
FBJ osteosarcoma oncogene B
chr6_-_124888643 5.83 ENSMUST00000032217.2
Lag3
lymphocyte-activation gene 3
chr14_+_119092107 5.75 ENSMUST00000100314.4
Cldn10
claudin 10
chr3_+_106943472 5.51 ENSMUST00000052718.5
Kcna3
potassium voltage-gated channel, shaker-related subfamily, member 3
chr15_-_37734579 5.47 ENSMUST00000145909.9
ENSMUST00000153775.9
Gm49397
Ncald
predicted gene, 49397
neurocalcin delta
chr9_-_108067552 5.29 ENSMUST00000035208.14
Bsn
bassoon
chr11_+_53410552 5.13 ENSMUST00000108987.8
ENSMUST00000121334.8
ENSMUST00000117061.8
Septin8
septin 8
chr6_+_85164420 4.83 ENSMUST00000045942.9
Emx1
empty spiracles homeobox 1
chr7_+_5059703 4.81 ENSMUST00000208042.2
ENSMUST00000207974.2
Ccdc106
coiled-coil domain containing 106
chr7_+_57240894 4.62 ENSMUST00000039697.14
Gabrb3
gamma-aminobutyric acid (GABA) A receptor, subunit beta 3
chr5_+_33176160 4.60 ENSMUST00000019109.8
Ywhah
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide
chr19_-_7183596 4.47 ENSMUST00000123594.8
Otub1
OTU domain, ubiquitin aldehyde binding 1
chr6_+_6863269 4.24 ENSMUST00000171311.8
ENSMUST00000160937.9
Dlx6
distal-less homeobox 6
chr10_-_79710067 4.19 ENSMUST00000166023.2
ENSMUST00000167707.2
ENSMUST00000165601.8
Plppr3
phospholipid phosphatase related 3
chr19_-_7183626 4.05 ENSMUST00000025679.11
Otub1
OTU domain, ubiquitin aldehyde binding 1
chr9_+_66257747 3.98 ENSMUST00000042824.13
Herc1
HECT and RLD domain containing E3 ubiquitin protein ligase family member 1
chr9_+_31191820 3.91 ENSMUST00000117389.8
ENSMUST00000215499.2
Prdm10
PR domain containing 10
chr5_+_136937035 3.86 ENSMUST00000199101.5
ENSMUST00000200153.5
Ift22
intraflagellar transport 22
chr7_+_5059855 3.79 ENSMUST00000208161.2
ENSMUST00000207215.2
Ccdc106
coiled-coil domain containing 106
chr10_-_79710044 3.75 ENSMUST00000167897.8
Plppr3
phospholipid phosphatase related 3
chr10_-_80382611 3.64 ENSMUST00000183233.9
ENSMUST00000182604.8
Rexo1
REX1, RNA exonuclease 1
chr7_+_5060159 3.56 ENSMUST00000045543.8
Ccdc106
coiled-coil domain containing 106
chr8_+_4216556 3.39 ENSMUST00000239400.2
ENSMUST00000177053.8
ENSMUST00000176149.9
ENSMUST00000176072.9
ENSMUST00000176825.3
Evi5l
ecotropic viral integration site 5 like
chr7_+_90125890 3.37 ENSMUST00000208919.2
Dlg2
discs large MAGUK scaffold protein 2
chr13_+_93441307 3.35 ENSMUST00000080127.12
Homer1
homer scaffolding protein 1
chr2_+_72306503 3.24 ENSMUST00000102691.11
ENSMUST00000157019.2
Cdca7
cell division cycle associated 7
chr11_-_102338473 3.22 ENSMUST00000049057.5
Fam171a2
family with sequence similarity 171, member A2
chr12_+_51640097 3.15 ENSMUST00000164782.10
ENSMUST00000085412.7
Coch
cochlin
chr8_+_26401698 2.92 ENSMUST00000120653.8
ENSMUST00000126226.2
Kcnu1
potassium channel, subfamily U, member 1
chr5_-_148865429 2.85 ENSMUST00000149169.3
ENSMUST00000047257.15
Katnal1
katanin p60 subunit A-like 1
chr15_+_78784043 2.84 ENSMUST00000001226.11
Sh3bp1
SH3-domain binding protein 1
chr12_+_102094977 2.81 ENSMUST00000159329.8
Slc24a4
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr11_+_79980210 2.79 ENSMUST00000017694.7
ENSMUST00000108239.7
Atad5
ATPase family, AAA domain containing 5
chr8_+_33876353 2.69 ENSMUST00000070340.6
ENSMUST00000078058.5
Purg
purine-rich element binding protein G
chr11_-_115405200 2.60 ENSMUST00000021083.7
Jpt1
Jupiter microtubule associated homolog 1
chr11_+_75422516 2.58 ENSMUST00000149727.8
ENSMUST00000108433.8
ENSMUST00000042561.14
ENSMUST00000143035.8
Slc43a2
solute carrier family 43, member 2
chr19_-_5323092 2.54 ENSMUST00000237463.2
ENSMUST00000025786.9
Pacs1
phosphofurin acidic cluster sorting protein 1
chr2_-_32271833 2.51 ENSMUST00000146423.2
1110008P14Rik
RIKEN cDNA 1110008P14 gene
chr5_+_30868908 2.51 ENSMUST00000114729.8
Dpysl5
dihydropyrimidinase-like 5
chr15_+_76130947 2.46 ENSMUST00000229772.2
ENSMUST00000230347.2
ENSMUST00000023225.8
Grina
glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)
chr9_+_67747668 2.35 ENSMUST00000077879.7
Vps13c
vacuolar protein sorting 13C
chrX_+_52001108 2.24 ENSMUST00000078944.13
ENSMUST00000101587.10
ENSMUST00000154864.4
Phf6
PHD finger protein 6
chr15_-_38518458 2.23 ENSMUST00000127848.2
Azin1
antizyme inhibitor 1
chr7_-_6334239 2.22 ENSMUST00000127658.2
ENSMUST00000062765.14
Zfp583
zinc finger protein 583
chr5_+_30869193 2.21 ENSMUST00000088081.11
ENSMUST00000101442.4
Dpysl5
dihydropyrimidinase-like 5
chr11_-_70578775 2.16 ENSMUST00000036299.14
ENSMUST00000119120.2
ENSMUST00000100933.10
Camta2
calmodulin binding transcription activator 2
chr7_+_135139542 2.15 ENSMUST00000073961.8
Ptpre
protein tyrosine phosphatase, receptor type, E
chr5_+_136937083 2.06 ENSMUST00000008131.10
Ift22
intraflagellar transport 22
chr6_+_6863769 2.02 ENSMUST00000031768.8
Dlx6
distal-less homeobox 6
chr19_+_41818409 2.02 ENSMUST00000087155.5
Frat1
frequently rearranged in advanced T cell lymphomas
chr7_-_141456092 1.92 ENSMUST00000055819.13
ENSMUST00000001950.12
Tollip
toll interacting protein
chr11_+_120612278 1.91 ENSMUST00000018156.12
Rac3
Rac family small GTPase 3
chr12_-_76756772 1.89 ENSMUST00000166101.2
Sptb
spectrin beta, erythrocytic
chr4_-_151946219 1.83 ENSMUST00000097774.9
Camta1
calmodulin binding transcription activator 1
chr2_-_118534444 1.79 ENSMUST00000104937.2
Ankrd63
ankyrin repeat domain 63
chr9_-_31824758 1.72 ENSMUST00000116615.5
Barx2
BarH-like homeobox 2
chr1_-_16727067 1.70 ENSMUST00000188641.7
Eloc
elongin C
chr7_-_141456045 1.67 ENSMUST00000130439.3
Tollip
toll interacting protein
chr11_+_75422925 1.65 ENSMUST00000169547.9
Slc43a2
solute carrier family 43, member 2
chr17_+_48037758 1.65 ENSMUST00000024782.12
ENSMUST00000144955.2
Pgc
progastricsin (pepsinogen C)
chr18_+_67266784 1.64 ENSMUST00000236918.2
Gnal
guanine nucleotide binding protein, alpha stimulating, olfactory type
chr6_+_142702403 1.61 ENSMUST00000032419.9
Cmas
cytidine monophospho-N-acetylneuraminic acid synthetase
chr2_+_158636727 1.61 ENSMUST00000029186.14
ENSMUST00000109478.9
ENSMUST00000156893.2
Dhx35
DEAH (Asp-Glu-Ala-His) box polypeptide 35
chr16_+_48814548 1.59 ENSMUST00000117994.8
ENSMUST00000048374.6
Cip2a
cell proliferation regulating inhibitor of protein phosphatase 2A
chr11_+_120612369 1.58 ENSMUST00000142229.2
Rac3
Rac family small GTPase 3
chr2_-_29142965 1.58 ENSMUST00000155949.2
ENSMUST00000154682.8
ENSMUST00000028141.6
ENSMUST00000071201.5
6530402F18Rik
Ntng2
RIKEN cDNA 6530402F18 gene
netrin G2
chr12_+_110245662 1.53 ENSMUST00000097228.5
Dio3
deiodinase, iodothyronine type III
chr11_-_70578905 1.52 ENSMUST00000108544.8
Camta2
calmodulin binding transcription activator 2
chr15_+_76131020 1.49 ENSMUST00000229380.2
Grina
glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)
chr11_+_75422953 1.46 ENSMUST00000127226.3
Slc43a2
solute carrier family 43, member 2
chr17_+_8529932 1.44 ENSMUST00000154553.2
ENSMUST00000140890.3
Sft2d1
Gm49987
SFT2 domain containing 1
predicted gene, 49987
chr12_-_110807330 1.42 ENSMUST00000177224.2
ENSMUST00000084974.11
ENSMUST00000070565.15
Mok
MOK protein kinase
chr19_+_8595369 1.41 ENSMUST00000010250.4
Slc22a6
solute carrier family 22 (organic anion transporter), member 6
chr5_-_92231517 1.40 ENSMUST00000202258.4
ENSMUST00000113127.7
G3bp2
GTPase activating protein (SH3 domain) binding protein 2
chr15_-_38518406 1.38 ENSMUST00000151319.8
Azin1
antizyme inhibitor 1
chr18_-_46345661 1.36 ENSMUST00000037011.6
Trim36
tripartite motif-containing 36
chr7_+_79939747 1.17 ENSMUST00000205864.2
Vps33b
vacuolar protein sorting 33B
chr18_-_35795233 1.16 ENSMUST00000025209.12
ENSMUST00000096573.4
Spata24
spermatogenesis associated 24
chr10_+_74896383 1.16 ENSMUST00000164107.3
Bcr
BCR activator of RhoGEF and GTPase
chr8_+_72993862 1.15 ENSMUST00000003117.15
ENSMUST00000212841.2
Ap1m1
adaptor-related protein complex AP-1, mu subunit 1
chr11_-_70578744 1.09 ENSMUST00000108545.9
ENSMUST00000120261.8
Camta2
calmodulin binding transcription activator 2
chr4_-_128856213 1.06 ENSMUST00000119354.8
ENSMUST00000106068.8
ENSMUST00000030581.10
Azin2
antizyme inhibitor 2
chr11_+_104122399 1.05 ENSMUST00000132977.8
ENSMUST00000132245.8
ENSMUST00000100347.11
Mapt
microtubule-associated protein tau
chr16_-_4867703 0.99 ENSMUST00000115844.3
ENSMUST00000023189.15
Glyr1
glyoxylate reductase 1 homolog (Arabidopsis)
chr2_+_121786892 0.96 ENSMUST00000110578.8
Ctdspl2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
chr10_-_93425553 0.92 ENSMUST00000020203.7
Snrpf
small nuclear ribonucleoprotein polypeptide F
chr3_+_133942244 0.83 ENSMUST00000181904.3
Cxxc4
CXXC finger 4
chr19_-_41836514 0.80 ENSMUST00000059231.4
Frat2
frequently rearranged in advanced T cell lymphomas 2
chr15_-_101588714 0.79 ENSMUST00000023786.7
Krt6b
keratin 6B
chr8_+_108162985 0.78 ENSMUST00000166615.3
ENSMUST00000213097.2
ENSMUST00000212205.2
Wwp2
WW domain containing E3 ubiquitin protein ligase 2
chr11_+_69792642 0.78 ENSMUST00000177138.8
ENSMUST00000108617.10
ENSMUST00000177476.8
ENSMUST00000061837.11
Neurl4
neuralized E3 ubiquitin protein ligase 4
chr11_+_104122341 0.77 ENSMUST00000106993.10
Mapt
microtubule-associated protein tau
chr2_+_121786444 0.75 ENSMUST00000036647.13
Ctdspl2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
chr2_-_84865831 0.74 ENSMUST00000028465.14
P2rx3
purinergic receptor P2X, ligand-gated ion channel, 3
chr18_-_35795175 0.73 ENSMUST00000236574.2
ENSMUST00000236971.2
Spata24
spermatogenesis associated 24
chr5_+_115417725 0.71 ENSMUST00000040421.11
Coq5
coenzyme Q5 methyltransferase
chr11_+_115455260 0.67 ENSMUST00000021085.11
Nup85
nucleoporin 85
chr11_-_100098333 0.66 ENSMUST00000007272.8
Krt14
keratin 14
chr11_+_69656725 0.65 ENSMUST00000108640.8
ENSMUST00000108639.8
Zbtb4
zinc finger and BTB domain containing 4
chr4_-_126150066 0.59 ENSMUST00000122129.8
ENSMUST00000061143.15
ENSMUST00000106132.3
Map7d1
MAP7 domain containing 1
chr1_-_16727242 0.49 ENSMUST00000186948.7
ENSMUST00000187910.7
ENSMUST00000115352.10
Eloc
elongin C
chr1_-_16727133 0.44 ENSMUST00000185771.7
Eloc
elongin C
chr10_+_84938452 0.40 ENSMUST00000095383.6
Tmem263
transmembrane protein 263
chr1_-_106641940 0.40 ENSMUST00000112751.2
Bcl2
B cell leukemia/lymphoma 2
chr11_+_68322945 0.39 ENSMUST00000021283.8
Pik3r5
phosphoinositide-3-kinase regulatory subunit 5
chr11_+_69656797 0.36 ENSMUST00000108642.8
ENSMUST00000156932.8
Zbtb4
zinc finger and BTB domain containing 4
chr5_-_134643805 0.35 ENSMUST00000202085.2
ENSMUST00000036362.13
ENSMUST00000077636.8
Lat2
linker for activation of T cells family, member 2
chr11_+_70453806 0.34 ENSMUST00000079244.12
ENSMUST00000102558.11
Mink1
misshapen-like kinase 1 (zebrafish)
chr1_-_171188302 0.23 ENSMUST00000061878.5
Klhdc9
kelch domain containing 9
chr2_+_174602574 0.23 ENSMUST00000140908.2
Edn3
endothelin 3
chr7_+_79992839 0.20 ENSMUST00000032747.7
ENSMUST00000206480.2
ENSMUST00000206074.2
ENSMUST00000206122.2
Hddc3
HD domain containing 3
chr16_-_22084700 0.19 ENSMUST00000161286.8
Tra2b
transformer 2 beta
chr7_+_35285657 0.19 ENSMUST00000040844.16
ENSMUST00000188906.7
ENSMUST00000186245.7
ENSMUST00000190503.7
Ankrd27
ankyrin repeat domain 27 (VPS9 domain)
chr5_+_108416763 0.16 ENSMUST00000031190.5
Dr1
down-regulator of transcription 1
chr2_+_119181703 0.16 ENSMUST00000028780.4
Chac1
ChaC, cation transport regulator 1
chr8_+_72993913 0.14 ENSMUST00000145213.8
Ap1m1
adaptor-related protein complex AP-1, mu subunit 1
chr2_-_121786573 0.12 ENSMUST00000104936.4
Mageb3
MAGE family member B3
chr15_-_101602734 0.05 ENSMUST00000023788.8
Krt6a
keratin 6A
chr11_-_70895213 0.02 ENSMUST00000124464.2
ENSMUST00000108527.8
Dhx33
DEAH (Asp-Glu-Ala-His) box polypeptide 33
chr13_-_30168374 0.01 ENSMUST00000221536.2
ENSMUST00000222730.2
E2f3
E2F transcription factor 3

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
13.4 67.0 GO:0098971 anterograde dendritic transport of neurotransmitter receptor complex(GO:0098971)
2.0 5.9 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
1.8 5.3 GO:0099526 presynaptic signal transduction(GO:0098928) presynapse to nucleus signaling pathway(GO:0099526)
1.5 4.6 GO:0006713 glucocorticoid catabolic process(GO:0006713)
1.2 4.7 GO:1902269 positive regulation of polyamine transmembrane transport(GO:1902269)
0.8 2.4 GO:1904924 negative regulation of mitophagy in response to mitochondrial depolarization(GO:1904924)
0.6 7.8 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.6 16.2 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.6 6.2 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.5 2.2 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.5 11.9 GO:0071420 cellular response to histamine(GO:0071420)
0.5 4.6 GO:0045085 negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.4 2.8 GO:0051013 microtubule severing(GO:0051013)
0.4 1.6 GO:0046381 CMP-N-acetylneuraminate metabolic process(GO:0046381)
0.4 9.8 GO:0021756 striatum development(GO:0021756)
0.3 3.5 GO:0021894 cerebral cortex GABAergic interneuron development(GO:0021894)
0.3 1.6 GO:0002225 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antibacterial peptide production(GO:0002803)
0.3 7.4 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.3 4.8 GO:0070445 oligodendrocyte progenitor proliferation(GO:0070444) regulation of oligodendrocyte progenitor proliferation(GO:0070445)
0.2 8.1 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.2 8.9 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.2 2.5 GO:0000042 protein targeting to Golgi(GO:0000042)
0.2 4.0 GO:0021702 cerebellar Purkinje cell differentiation(GO:0021702)
0.2 8.4 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.2 8.5 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.2 1.6 GO:0009405 pathogenesis(GO:0009405)
0.2 3.4 GO:0045161 neuronal ion channel clustering(GO:0045161)
0.2 2.8 GO:0048304 positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.2 3.4 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.2 1.2 GO:0070889 platelet alpha granule organization(GO:0070889)
0.2 12.1 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.2 1.5 GO:1900034 regulation of cellular response to heat(GO:1900034)
0.2 1.5 GO:0019336 phenol-containing compound catabolic process(GO:0019336)
0.1 0.7 GO:1904058 positive regulation of sensory perception of pain(GO:1904058)
0.1 3.9 GO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236)
0.1 1.2 GO:0060313 negative regulation of neutrophil degranulation(GO:0043314) negative regulation of blood vessel remodeling(GO:0060313)
0.1 3.6 GO:0036010 protein localization to endosome(GO:0036010)
0.1 7.2 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.1 1.7 GO:0042637 catagen(GO:0042637)
0.1 0.4 GO:0019740 regulation of nitrogen utilization(GO:0006808) positive regulation of neuron maturation(GO:0014042) nitrogen utilization(GO:0019740)
0.1 2.8 GO:0097186 amelogenesis(GO:0097186)
0.1 5.9 GO:0042073 intraciliary transport(GO:0042073)
0.1 0.7 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.1 1.4 GO:0015747 urate transport(GO:0015747)
0.1 7.4 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.1 1.4 GO:0048757 endosome to melanosome transport(GO:0035646) endosome to pigment granule transport(GO:0043485) pigment granule maturation(GO:0048757)
0.1 2.6 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.1 3.0 GO:0003299 muscle hypertrophy in response to stress(GO:0003299) cardiac muscle adaptation(GO:0014887) cardiac muscle hypertrophy in response to stress(GO:0014898)
0.1 5.7 GO:0015807 L-amino acid transport(GO:0015807)
0.1 1.4 GO:0034063 stress granule assembly(GO:0034063)
0.1 5.9 GO:0071277 cellular response to calcium ion(GO:0071277)
0.1 7.3 GO:0030032 lamellipodium assembly(GO:0030032)
0.1 6.7 GO:0032024 positive regulation of insulin secretion(GO:0032024)
0.1 1.5 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 1.9 GO:0006779 porphyrin-containing compound biosynthetic process(GO:0006779)
0.0 5.7 GO:0003073 regulation of systemic arterial blood pressure(GO:0003073)
0.0 3.4 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.0 0.8 GO:0045109 intermediate filament organization(GO:0045109)
0.0 9.2 GO:0071805 potassium ion transmembrane transport(GO:0071805)
0.0 2.0 GO:0006611 protein export from nucleus(GO:0006611)
0.0 0.7 GO:0006744 ubiquinone biosynthetic process(GO:0006744)
0.0 6.0 GO:0050679 positive regulation of epithelial cell proliferation(GO:0050679)
0.0 1.4 GO:0007340 acrosome reaction(GO:0007340)
0.0 0.9 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 0.2 GO:0006751 glutathione catabolic process(GO:0006751)
0.0 0.2 GO:1990403 embryonic brain development(GO:1990403)
0.0 9.7 GO:0007283 spermatogenesis(GO:0007283)
0.0 3.2 GO:0008360 regulation of cell shape(GO:0008360)
0.0 0.4 GO:0043551 regulation of phosphatidylinositol 3-kinase activity(GO:0043551)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.6 67.0 GO:0035253 ciliary rootlet(GO:0035253)
2.0 5.9 GO:0098843 postsynaptic endocytic zone(GO:0098843)
1.8 5.3 GO:1990257 piccolo-bassoon transport vesicle(GO:1990257)
1.6 12.9 GO:0000836 ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836)
0.8 23.1 GO:1902711 GABA-A receptor complex(GO:1902711)
0.6 7.4 GO:0032591 dendritic spine membrane(GO:0032591)
0.4 2.6 GO:0070449 elongin complex(GO:0070449)
0.4 18.5 GO:0045095 keratin filament(GO:0045095)
0.4 7.4 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.2 1.9 GO:0008091 spectrin(GO:0008091)
0.2 3.4 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.2 1.5 GO:0045298 tubulin complex(GO:0045298)
0.2 5.9 GO:0030992 intraciliary transport particle B(GO:0030992)
0.2 6.2 GO:0033270 paranode region of axon(GO:0033270)
0.2 0.9 GO:0005683 U7 snRNP(GO:0005683)
0.1 8.9 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.1 1.2 GO:0071439 clathrin complex(GO:0071439)
0.1 1.1 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.1 2.5 GO:0030137 COPI-coated vesicle(GO:0030137)
0.1 0.4 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.1 16.0 GO:0001650 fibrillar center(GO:0001650)
0.1 3.4 GO:0043034 costamere(GO:0043034)
0.1 8.4 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 0.7 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 4.6 GO:0014704 intercalated disc(GO:0014704)
0.0 3.5 GO:0031941 filamentous actin(GO:0031941)
0.0 1.2 GO:0097546 ciliary base(GO:0097546)
0.0 1.0 GO:0000786 nucleosome(GO:0000786)
0.0 1.2 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 1.6 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.2 GO:0097422 tubular endosome(GO:0097422)
0.0 1.6 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 10.5 GO:0043235 receptor complex(GO:0043235)
0.0 14.1 GO:0030425 dendrite(GO:0030425)
0.0 2.6 GO:0005923 bicellular tight junction(GO:0005923)
0.0 1.4 GO:0005901 caveola(GO:0005901)
0.0 2.2 GO:0000776 kinetochore(GO:0000776)
0.0 1.6 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.0 0.3 GO:0046930 pore complex(GO:0046930)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 67.0 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
2.0 5.9 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798)
1.3 7.8 GO:0030280 structural constituent of epidermis(GO:0030280)
1.2 8.5 GO:0019784 NEDD8-specific protease activity(GO:0019784)
1.2 11.9 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
1.2 4.7 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
1.0 16.2 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
1.0 5.8 GO:0042289 MHC class II protein binding(GO:0042289)
0.7 3.6 GO:0005150 interleukin-1, Type I receptor binding(GO:0005150)
0.7 12.9 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.5 7.9 GO:0042577 lipid phosphatase activity(GO:0042577)
0.5 11.2 GO:0050811 GABA receptor binding(GO:0050811)
0.5 2.8 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.5 2.8 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.4 1.5 GO:0099609 microtubule lateral binding(GO:0099609)
0.4 1.5 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.4 2.9 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.3 1.0 GO:0010428 methyl-CpNpG binding(GO:0010428)
0.3 1.0 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.3 3.4 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
0.3 5.5 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.2 8.9 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.2 5.2 GO:0001222 transcription corepressor binding(GO:0001222)
0.2 1.6 GO:0070567 cytidylyltransferase activity(GO:0070567)
0.2 6.6 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.2 0.7 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.1 3.4 GO:0004385 guanylate kinase activity(GO:0004385)
0.1 0.7 GO:1990254 keratin filament binding(GO:1990254)
0.1 5.5 GO:0043014 alpha-tubulin binding(GO:0043014)
0.1 8.1 GO:0001540 beta-amyloid binding(GO:0001540)
0.1 3.8 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.1 1.4 GO:0031404 chloride ion binding(GO:0031404)
0.1 5.7 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.1 15.2 GO:0017124 SH3 domain binding(GO:0017124)
0.1 0.2 GO:0031708 endothelin B receptor binding(GO:0031708)
0.1 1.6 GO:0004190 aspartic-type endopeptidase activity(GO:0004190)
0.1 8.3 GO:0030165 PDZ domain binding(GO:0030165)
0.1 7.4 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 1.6 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 1.9 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.4 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.4 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 3.6 GO:0004527 exonuclease activity(GO:0004527)
0.0 3.2 GO:0005518 collagen binding(GO:0005518)
0.0 3.5 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 6.5 GO:0044325 ion channel binding(GO:0044325)
0.0 5.8 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 4.7 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds(GO:0016810)
0.0 1.4 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 0.2 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.0 3.4 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 3.2 GO:0004721 phosphoprotein phosphatase activity(GO:0004721)
0.0 0.8 GO:0001190 transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.0 5.0 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 17.1 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.1 6.9 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.1 1.5 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 5.9 PID AP1 PATHWAY AP-1 transcription factor network
0.1 1.5 PID LPA4 PATHWAY LPA4-mediated signaling events
0.1 6.6 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.1 6.9 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.1 2.7 PID IL1 PATHWAY IL1-mediated signaling events
0.1 2.9 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.1 1.2 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 2.2 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 1.2 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.4 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.0 3.2 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.4 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 67.0 REACTOME KINESINS Genes involved in Kinesins
1.0 23.1 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.4 1.6 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.4 3.6 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.3 5.5 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.3 16.0 REACTOME CA DEPENDENT EVENTS Genes involved in Ca-dependent events
0.2 3.7 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.2 4.7 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.1 2.8 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.1 1.4 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.1 5.7 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.1 5.5 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.1 2.9 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.1 0.9 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.1 6.6 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.1 1.5 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.1 3.6 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 13.2 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 1.5 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 6.1 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 1.9 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 2.8 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.7 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0 0.4 REACTOME INFLAMMASOMES Genes involved in Inflammasomes