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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Zfhx3

Z-value: 0.97

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Transcription factors associated with Zfhx3

Gene Symbol Gene ID Gene Info
Zfhx3
ENSMUSG00000038872.11 Zfhx3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Zfhx3mm39_v1_chr8_+_108669276_108669276-0.132.9e-01Click!

Activity profile of Zfhx3 motif

Sorted Z-values of Zfhx3 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Zfhx3

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr4_+_98919183 29.70 ENSMUST00000030280.7
Angptl3
angiopoietin-like 3
chr19_+_30210320 13.14 ENSMUST00000025797.7
Mbl2
mannose-binding lectin (protein C) 2
chr3_+_82933383 12.80 ENSMUST00000029630.15
ENSMUST00000166581.4
Fga
fibrinogen alpha chain
chr2_-_34951443 12.68 ENSMUST00000028233.7
Hc
hemolytic complement
chr15_-_96929086 12.23 ENSMUST00000230086.2
Slc38a4
solute carrier family 38, member 4
chr17_+_12597490 12.11 ENSMUST00000014578.7
Plg
plasminogen
chr2_-_34990689 11.66 ENSMUST00000226631.2
ENSMUST00000045776.5
ENSMUST00000226972.2
AI182371
expressed sequence AI182371
chr13_-_56696222 10.03 ENSMUST00000225183.2
Lect2
leukocyte cell-derived chemotaxin 2
chr1_+_172525613 9.91 ENSMUST00000038495.5
Crp
C-reactive protein, pentraxin-related
chr15_-_60793115 9.87 ENSMUST00000096418.5
A1bg
alpha-1-B glycoprotein
chr6_-_141892517 9.78 ENSMUST00000168119.8
Slco1a1
solute carrier organic anion transporter family, member 1a1
chr1_-_172722589 9.13 ENSMUST00000027824.7
Apcs
serum amyloid P-component
chr7_+_30193047 8.54 ENSMUST00000058280.13
ENSMUST00000133318.8
ENSMUST00000142575.8
ENSMUST00000131040.2
Prodh2
proline dehydrogenase (oxidase) 2
chr9_-_70841881 8.52 ENSMUST00000214995.2
Lipc
lipase, hepatic
chr9_-_70842090 7.87 ENSMUST00000034731.10
Lipc
lipase, hepatic
chr4_-_6275629 7.66 ENSMUST00000029905.2
Cyp7a1
cytochrome P450, family 7, subfamily a, polypeptide 1
chr11_+_101258368 7.57 ENSMUST00000019469.3
G6pc
glucose-6-phosphatase, catalytic
chr1_+_88093726 7.49 ENSMUST00000097659.5
Ugt1a5
UDP glucuronosyltransferase 1 family, polypeptide A5
chr13_-_56696310 7.15 ENSMUST00000062806.6
Lect2
leukocyte cell-derived chemotaxin 2
chr3_+_137923521 6.54 ENSMUST00000090171.7
Adh7
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr13_+_24023428 5.65 ENSMUST00000091698.12
ENSMUST00000110422.3
ENSMUST00000166467.9
Slc17a3
solute carrier family 17 (sodium phosphate), member 3
chr11_+_70410445 4.98 ENSMUST00000179000.2
Gltpd2
glycolipid transfer protein domain containing 2
chr13_-_24098981 4.68 ENSMUST00000110407.4
Slc17a4
solute carrier family 17 (sodium phosphate), member 4
chr11_+_70410009 4.35 ENSMUST00000057685.3
Gltpd2
glycolipid transfer protein domain containing 2
chr2_-_25517945 4.34 ENSMUST00000028307.9
Fcna
ficolin A
chr13_-_24098951 4.33 ENSMUST00000021769.16
Slc17a4
solute carrier family 17 (sodium phosphate), member 4
chr5_+_35198853 4.15 ENSMUST00000030985.10
ENSMUST00000202573.2
Hgfac
hepatocyte growth factor activator
chr2_-_134396268 3.91 ENSMUST00000028704.3
Hao1
hydroxyacid oxidase 1, liver
chr3_-_137837117 3.88 ENSMUST00000029805.13
Mttp
microsomal triglyceride transfer protein
chr13_+_24023386 3.78 ENSMUST00000039721.14
Slc17a3
solute carrier family 17 (sodium phosphate), member 3
chrM_+_9870 3.70 ENSMUST00000084013.1
mt-Nd4l
mitochondrially encoded NADH dehydrogenase 4L
chr17_-_79292856 3.57 ENSMUST00000118991.2
Prkd3
protein kinase D3
chr7_+_51537645 3.53 ENSMUST00000208711.2
Gas2
growth arrest specific 2
chr2_+_162829250 3.38 ENSMUST00000018012.14
Sgk2
serum/glucocorticoid regulated kinase 2
chr5_-_38649291 3.38 ENSMUST00000129099.8
Slc2a9
solute carrier family 2 (facilitated glucose transporter), member 9
chr17_+_79919267 3.10 ENSMUST00000223924.2
Rmdn2
regulator of microtubule dynamics 2
chr2_+_162829422 2.90 ENSMUST00000117123.2
Sgk2
serum/glucocorticoid regulated kinase 2
chr11_+_78356523 2.76 ENSMUST00000001126.4
Slc46a1
solute carrier family 46, member 1
chr19_-_46661321 2.60 ENSMUST00000026012.8
Cyp17a1
cytochrome P450, family 17, subfamily a, polypeptide 1
chr4_+_150938376 2.48 ENSMUST00000073600.9
Errfi1
ERBB receptor feedback inhibitor 1
chr15_+_99291455 2.37 ENSMUST00000162624.8
Tmbim6
transmembrane BAX inhibitor motif containing 6
chr12_+_59142439 2.34 ENSMUST00000219140.3
Mia2
MIA SH3 domain ER export factor 2
chr15_+_99291491 2.33 ENSMUST00000159531.3
Tmbim6
transmembrane BAX inhibitor motif containing 6
chr15_+_31224616 2.27 ENSMUST00000186547.7
Dap
death-associated protein
chr19_-_46661501 2.23 ENSMUST00000236174.2
Cyp17a1
cytochrome P450, family 17, subfamily a, polypeptide 1
chr15_+_31225302 2.20 ENSMUST00000186425.7
Dap
death-associated protein
chr18_-_66155651 2.14 ENSMUST00000143990.2
Lman1
lectin, mannose-binding, 1
chr15_+_31224460 2.13 ENSMUST00000044524.16
Dap
death-associated protein
chrM_+_9459 1.99 ENSMUST00000082411.1
mt-Nd3
mitochondrially encoded NADH dehydrogenase 3
chr18_+_36414122 1.95 ENSMUST00000051301.6
Pura
purine rich element binding protein A
chr4_+_138694422 1.87 ENSMUST00000116094.5
ENSMUST00000239443.2
Rnf186
ring finger protein 186
chr11_+_114566257 1.84 ENSMUST00000045779.6
Ttyh2
tweety family member 2
chr15_+_31224555 1.73 ENSMUST00000186109.2
Dap
death-associated protein
chr2_+_152873772 1.69 ENSMUST00000037235.7
Xkr7
X-linked Kx blood group related 7
chr5_-_28672091 1.67 ENSMUST00000002708.5
Shh
sonic hedgehog
chr6_+_113460258 1.63 ENSMUST00000032422.6
Creld1
cysteine-rich with EGF-like domains 1
chr14_+_26722319 1.56 ENSMUST00000035433.10
Hesx1
homeobox gene expressed in ES cells
chr7_-_99629637 1.52 ENSMUST00000080817.6
Rnf169
ring finger protein 169
chr2_+_120807498 1.36 ENSMUST00000067582.14
Tmem62
transmembrane protein 62
chr3_+_85946145 1.18 ENSMUST00000238331.2
Sh3d19
SH3 domain protein D19
chrM_+_14138 1.16 ENSMUST00000082421.1
mt-Cytb
mitochondrially encoded cytochrome b
chr1_-_80439165 1.14 ENSMUST00000211023.2
Gm45261
predicted gene 45261
chr2_-_63014514 1.11 ENSMUST00000112452.2
Kcnh7
potassium voltage-gated channel, subfamily H (eag-related), member 7
chrX_-_142716085 1.09 ENSMUST00000087313.10
Dcx
doublecortin
chr2_+_85868891 1.09 ENSMUST00000218397.2
Olfr1033
olfactory receptor 1033
chr2_+_152907875 1.05 ENSMUST00000238488.2
ENSMUST00000129377.8
ENSMUST00000109800.2
Ccm2l
cerebral cavernous malformation 2-like
chr17_-_37611375 1.04 ENSMUST00000058046.6
Olfr101
olfactory receptor 101
chr2_-_140513382 1.02 ENSMUST00000110057.3
Flrt3
fibronectin leucine rich transmembrane protein 3
chrM_+_7006 1.02 ENSMUST00000082405.1
mt-Co2
mitochondrially encoded cytochrome c oxidase II
chr2_+_81883566 1.00 ENSMUST00000047527.8
Zfp804a
zinc finger protein 804A
chr4_-_42168603 1.00 ENSMUST00000098121.4
Gm13305
predicted gene 13305
chr4_-_42665763 1.00 ENSMUST00000238770.2
Il11ra2
interleukin 11 receptor, alpha chain 2
chr6_-_93769426 0.90 ENSMUST00000204788.2
Magi1
membrane associated guanylate kinase, WW and PDZ domain containing 1
chr1_-_126758520 0.86 ENSMUST00000162646.8
Nckap5
NCK-associated protein 5
chr3_-_98364359 0.84 ENSMUST00000188356.3
ENSMUST00000167753.8
Gm4450
predicted gene 4450
chr14_+_75368939 0.83 ENSMUST00000125833.8
ENSMUST00000124499.8
Lcp1
lymphocyte cytosolic protein 1
chr18_+_36661198 0.81 ENSMUST00000237174.2
ENSMUST00000236124.2
ENSMUST00000236779.2
ENSMUST00000235181.2
ENSMUST00000074298.13
ENSMUST00000115694.3
ENSMUST00000236126.2
Slc4a9
solute carrier family 4, sodium bicarbonate cotransporter, member 9
chr8_-_68270936 0.80 ENSMUST00000120071.8
Psd3
pleckstrin and Sec7 domain containing 3
chr7_-_12829100 0.79 ENSMUST00000209822.3
ENSMUST00000235753.2
Vmn1r85
vomeronasal 1 receptor 85
chr7_-_101486983 0.79 ENSMUST00000185929.2
ENSMUST00000165052.8
Inppl1
inositol polyphosphate phosphatase-like 1
chr15_+_39255185 0.78 ENSMUST00000228839.2
Rims2
regulating synaptic membrane exocytosis 2
chr2_-_63014622 0.76 ENSMUST00000075052.10
ENSMUST00000112454.8
Kcnh7
potassium voltage-gated channel, subfamily H (eag-related), member 7
chr14_-_30973164 0.75 ENSMUST00000226565.2
ENSMUST00000022459.5
Phf7
PHD finger protein 7
chrX_-_105647282 0.74 ENSMUST00000113480.2
Cysltr1
cysteinyl leukotriene receptor 1
chr2_-_140513320 0.74 ENSMUST00000056760.4
Flrt3
fibronectin leucine rich transmembrane protein 3
chr1_-_126758369 0.73 ENSMUST00000112583.8
ENSMUST00000094609.10
Nckap5
NCK-associated protein 5
chr17_+_38143840 0.71 ENSMUST00000213857.2
Olfr125
olfactory receptor 125
chr13_-_18556626 0.70 ENSMUST00000139064.10
ENSMUST00000175703.9
Pou6f2
POU domain, class 6, transcription factor 2
chr11_-_99482165 0.69 ENSMUST00000104930.2
Krtap1-3
keratin associated protein 1-3
chr9_+_7571397 0.67 ENSMUST00000120900.8
ENSMUST00000151853.8
ENSMUST00000152878.3
Mmp27
matrix metallopeptidase 27
chrX_+_111150171 0.66 ENSMUST00000164272.3
ENSMUST00000132037.2
4933403O08Rik
RIKEN cDNA 4933403O08 gene
chr14_+_33073249 0.64 ENSMUST00000140711.3
Arhgap22
Rho GTPase activating protein 22
chr7_+_18853778 0.59 ENSMUST00000053109.5
Fbxo46
F-box protein 46
chr2_-_165210622 0.58 ENSMUST00000141140.2
ENSMUST00000103085.8
Zfp663
zinc finger protein 663
chr2_+_69727599 0.58 ENSMUST00000131553.2
Ubr3
ubiquitin protein ligase E3 component n-recognin 3
chr2_+_69727563 0.57 ENSMUST00000055758.16
ENSMUST00000112251.9
Ubr3
ubiquitin protein ligase E3 component n-recognin 3
chr16_+_16688692 0.57 ENSMUST00000232547.2
Top3b
topoisomerase (DNA) III beta
chrX_+_159551171 0.55 ENSMUST00000112368.3
Rs1
retinoschisis (X-linked, juvenile) 1 (human)
chr16_-_56748424 0.53 ENSMUST00000210579.2
Lnp1
leukemia NUP98 fusion partner 1
chr14_+_75368532 0.53 ENSMUST00000143539.8
ENSMUST00000134114.8
Lcp1
lymphocyte cytosolic protein 1
chr2_-_86218905 0.51 ENSMUST00000213998.2
Olfr1058
olfactory receptor 1058
chr5_+_117378510 0.51 ENSMUST00000111975.3
Taok3
TAO kinase 3
chr2_+_87725306 0.50 ENSMUST00000217436.2
Olfr1153
olfactory receptor 1153
chr4_+_109092829 0.48 ENSMUST00000030285.8
Calr4
calreticulin 4
chr7_-_107633196 0.48 ENSMUST00000210173.3
Olfr478
olfactory receptor 478
chrX_+_159551009 0.46 ENSMUST00000033650.14
Rs1
retinoschisis (X-linked, juvenile) 1 (human)
chr7_+_102420428 0.46 ENSMUST00000213432.2
Olfr561
olfactory receptor 561
chr10_-_129593612 0.46 ENSMUST00000213379.2
ENSMUST00000217106.2
Olfr807
olfactory receptor 807
chrX_-_110446022 0.44 ENSMUST00000156639.2
Rps6ka6
ribosomal protein S6 kinase polypeptide 6
chr10_-_56104732 0.43 ENSMUST00000099739.5
Tbc1d32
TBC1 domain family, member 32
chr1_+_179788037 0.42 ENSMUST00000097453.9
ENSMUST00000111117.8
Cdc42bpa
CDC42 binding protein kinase alpha
chr6_+_48906825 0.42 ENSMUST00000031837.8
Doxl1
diamine oxidase-like protein 1
chr4_+_109092610 0.39 ENSMUST00000106628.8
Calr4
calreticulin 4
chr10_-_129591354 0.37 ENSMUST00000059038.3
Olfr807
olfactory receptor 807
chr14_-_50476340 0.36 ENSMUST00000059565.2
Olfr731
olfactory receptor 731
chr7_-_10011933 0.36 ENSMUST00000227719.2
ENSMUST00000228622.2
ENSMUST00000228086.2
Vmn1r66
vomeronasal 1 receptor 66
chr7_+_102834996 0.36 ENSMUST00000218618.2
Olfr592
olfactory receptor 592
chr6_+_21986445 0.31 ENSMUST00000115382.8
Cped1
cadherin-like and PC-esterase domain containing 1
chr5_-_66672158 0.28 ENSMUST00000161879.8
ENSMUST00000159357.8
Apbb2
amyloid beta (A4) precursor protein-binding, family B, member 2
chr11_-_70560110 0.28 ENSMUST00000129434.2
ENSMUST00000018431.13
Spag7
sperm associated antigen 7
chr7_-_139953579 0.27 ENSMUST00000074177.3
Olfr530
olfactory receptor 530
chr4_+_109092459 0.25 ENSMUST00000106631.9
Calr4
calreticulin 4
chr5_-_87638728 0.23 ENSMUST00000147854.6
Ugt2a1
UDP glucuronosyltransferase 2 family, polypeptide A1
chr8_+_34006758 0.23 ENSMUST00000149399.8
Tex15
testis expressed gene 15
chr5_-_86521273 0.23 ENSMUST00000031175.12
Tmprss11d
transmembrane protease, serine 11d
chr3_+_108479015 0.22 ENSMUST00000143054.2
Taf13
TATA-box binding protein associated factor 13
chr10_-_107747995 0.21 ENSMUST00000165341.5
Otogl
otogelin-like
chr1_-_4430481 0.20 ENSMUST00000027032.6
Rp1
retinitis pigmentosa 1 (human)
chr2_-_72817060 0.20 ENSMUST00000112062.2
Gm11084
predicted gene 11084
chrX_-_142716200 0.19 ENSMUST00000112851.8
ENSMUST00000112856.3
ENSMUST00000033642.10
Dcx
doublecortin
chr1_-_157084252 0.17 ENSMUST00000134543.8
Rasal2
RAS protein activator like 2
chr7_+_105017437 0.17 ENSMUST00000098152.3
ENSMUST00000217827.2
Olfr692
olfactory receptor 692
chr2_-_111880531 0.17 ENSMUST00000213582.2
ENSMUST00000213961.3
ENSMUST00000215531.2
Olfr1312
olfactory receptor 1312
chr4_+_115741581 0.16 ENSMUST00000097918.3
Kncn
kinocilin
chrX_+_71016592 0.15 ENSMUST00000066116.8
Fate1
fetal and adult testis expressed 1
chr6_+_132886614 0.15 ENSMUST00000076119.6
Tas2r125
taste receptor, type 2, member 125
chrM_-_14061 0.14 ENSMUST00000082419.1
mt-Nd6
mitochondrially encoded NADH dehydrogenase 6
chr18_+_56695515 0.14 ENSMUST00000130163.8
ENSMUST00000132628.8
Phax
phosphorylated adaptor for RNA export
chr7_+_104274001 0.13 ENSMUST00000215454.3
ENSMUST00000213297.2
Olfr657
olfactory receptor 657
chr9_-_48876290 0.12 ENSMUST00000008734.5
Htr3b
5-hydroxytryptamine (serotonin) receptor 3B
chr3_-_103553347 0.12 ENSMUST00000117271.3
Atg4a-ps
autophagy related 4A, pseudogene
chr7_-_28661751 0.12 ENSMUST00000068045.14
ENSMUST00000217157.2
Actn4
actinin alpha 4
chr3_+_125197722 0.09 ENSMUST00000173932.8
Ndst4
N-deacetylase/N-sulfotransferase (heparin glucosaminyl) 4
chr19_+_48194464 0.09 ENSMUST00000078880.6
Sorcs3
sortilin-related VPS10 domain containing receptor 3
chr5_-_137784912 0.07 ENSMUST00000031740.16
Mepce
methylphosphate capping enzyme
chr7_+_4340708 0.05 ENSMUST00000006792.6
ENSMUST00000126417.3
Ncr1
natural cytotoxicity triggering receptor 1
chr2_-_89195205 0.03 ENSMUST00000111543.2
ENSMUST00000137692.3
Olfr1234
olfactory receptor 1234
chr19_+_58500411 0.02 ENSMUST00000235305.2
ENSMUST00000069419.8
Ccdc172
coiled-coil domain containing 172
chr10_+_90412114 0.01 ENSMUST00000182427.8
ENSMUST00000182053.8
ENSMUST00000182113.8
Anks1b
ankyrin repeat and sterile alpha motif domain containing 1B

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
5.0 29.7 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
3.3 16.4 GO:0034371 chylomicron remodeling(GO:0034371)
3.2 12.8 GO:0043152 induction of bacterial agglutination(GO:0043152)
3.0 9.1 GO:0052203 modulation by symbiont of host molecular function(GO:0052055) modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422)
2.8 8.5 GO:0010133 proline catabolic process to glutamate(GO:0010133)
2.5 12.7 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
2.4 12.1 GO:0051919 positive regulation of fibrinolysis(GO:0051919)
1.6 6.5 GO:0006069 ethanol oxidation(GO:0006069)
1.5 7.7 GO:0070859 positive regulation of bile acid biosynthetic process(GO:0070859) positive regulation of bile acid metabolic process(GO:1904253)
1.3 17.5 GO:0001867 complement activation, lectin pathway(GO:0001867)
1.2 9.9 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.9 4.7 GO:1904720 regulation of mRNA cleavage(GO:0031437) negative regulation of mRNA cleavage(GO:0031438) regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904720) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
0.9 20.4 GO:0046415 urate metabolic process(GO:0046415)
0.8 3.9 GO:0009441 glycolate metabolic process(GO:0009441)
0.6 7.5 GO:0052696 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.6 1.7 GO:1904339 intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908) kidney smooth muscle tissue development(GO:0072194) negative regulation of dopaminergic neuron differentiation(GO:1904339) positive regulation of mesenchymal cell proliferation involved in ureter development(GO:2000729)
0.5 3.6 GO:0089700 protein kinase D signaling(GO:0089700)
0.4 3.9 GO:0034197 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.4 2.5 GO:1903243 negative regulation of cardiac muscle adaptation(GO:0010616) negative regulation of cardiac muscle hypertrophy in response to stress(GO:1903243)
0.4 2.8 GO:0015886 heme transport(GO:0015886) methotrexate transport(GO:0051958)
0.3 9.8 GO:0035634 response to stilbenoid(GO:0035634)
0.3 1.2 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.3 1.0 GO:0016062 adaptation of rhodopsin mediated signaling(GO:0016062) light adaption(GO:0036367)
0.2 12.2 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.2 4.8 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)
0.2 1.1 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.2 1.9 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.2 1.8 GO:0003344 pericardium morphogenesis(GO:0003344)
0.1 1.2 GO:0033762 response to glucagon(GO:0033762)
0.1 1.6 GO:0030916 otic vesicle formation(GO:0030916)
0.1 8.3 GO:0034198 cellular response to amino acid starvation(GO:0034198)
0.1 0.8 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.1 1.5 GO:2000780 negative regulation of double-strand break repair(GO:2000780)
0.1 0.6 GO:0006265 DNA topological change(GO:0006265)
0.1 0.8 GO:0098814 spontaneous neurotransmitter secretion(GO:0061669) positive regulation of inhibitory postsynaptic potential(GO:0097151) spontaneous synaptic transmission(GO:0098814)
0.1 4.0 GO:0042773 ATP synthesis coupled electron transport(GO:0042773)
0.1 1.4 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.1 0.2 GO:0052695 cellular glucuronidation(GO:0052695)
0.1 9.0 GO:0035725 sodium ion transmembrane transport(GO:0035725)
0.1 1.3 GO:0021860 pyramidal neuron development(GO:0021860)
0.1 2.3 GO:0055090 acylglycerol homeostasis(GO:0055090) triglyceride homeostasis(GO:0070328)
0.1 1.2 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 11.1 GO:0030178 negative regulation of Wnt signaling pathway(GO:0030178)
0.0 0.4 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.0 5.7 GO:0032411 positive regulation of transporter activity(GO:0032411)
0.0 0.1 GO:0051030 snRNA transport(GO:0051030)
0.0 0.4 GO:2000381 negative regulation of mesoderm development(GO:2000381)
0.0 2.0 GO:0071385 cellular response to glucocorticoid stimulus(GO:0071385)
0.0 0.1 GO:1902396 protein localization to bicellular tight junction(GO:1902396)
0.0 0.5 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 3.8 GO:0007050 cell cycle arrest(GO:0007050)
0.0 0.6 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.2 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.0 1.8 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.0 0.2 GO:0019321 pentose metabolic process(GO:0019321)
0.0 0.7 GO:0045907 positive regulation of vasoconstriction(GO:0045907)
0.0 0.2 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.0 0.1 GO:0009597 detection of virus(GO:0009597)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 12.1 GO:0044279 other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
1.6 12.7 GO:0005579 membrane attack complex(GO:0005579)
1.4 12.8 GO:0005577 fibrinogen complex(GO:0005577)
0.4 16.4 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.1 15.9 GO:0005581 collagen trimer(GO:0005581)
0.1 1.9 GO:0005662 DNA replication factor A complex(GO:0005662)
0.1 5.7 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.1 2.1 GO:0030430 host cell cytoplasm(GO:0030430) host cell cytoplasm part(GO:0033655)
0.1 1.2 GO:0045275 respiratory chain complex III(GO:0045275)
0.1 0.7 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.1 8.0 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.1 28.0 GO:0005769 early endosome(GO:0005769)
0.1 19.0 GO:0072562 blood microparticle(GO:0072562)
0.1 1.0 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.1 2.3 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.1 1.4 GO:0001891 phagocytic cup(GO:0001891)
0.0 7.6 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 0.1 GO:1904602 serotonin-activated cation-selective channel complex(GO:1904602)
0.0 1.5 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.1 GO:0070469 respiratory chain(GO:0070469)
0.0 10.7 GO:0030426 growth cone(GO:0030426)
0.0 10.5 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 2.6 GO:0031526 brush border membrane(GO:0031526)
0.0 0.2 GO:0060091 kinocilium(GO:0060091)
0.0 0.2 GO:0097542 ciliary tip(GO:0097542)
0.0 0.8 GO:0048786 presynaptic active zone(GO:0048786)
0.0 3.0 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 6.5 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 0.6 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.1 GO:0031143 pseudopodium(GO:0031143)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
3.3 16.4 GO:0035478 chylomicron binding(GO:0035478)
2.7 29.7 GO:0004859 phospholipase inhibitor activity(GO:0004859)
2.4 19.0 GO:0001849 complement component C1q binding(GO:0001849)
2.2 6.5 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
1.9 7.6 GO:0050309 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
1.6 13.1 GO:0005534 galactose binding(GO:0005534)
1.2 18.4 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
1.0 3.9 GO:0016899 oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.8 4.7 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.8 12.1 GO:1990405 protein antigen binding(GO:1990405)
0.5 1.9 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.5 2.8 GO:0015232 heme transporter activity(GO:0015232)
0.4 8.3 GO:0070513 death domain binding(GO:0070513)
0.2 6.3 GO:0017081 chloride channel regulator activity(GO:0017081)
0.2 8.5 GO:0071949 FAD binding(GO:0071949)
0.2 4.8 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.2 3.4 GO:1901702 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.2 1.7 GO:0043237 laminin-1 binding(GO:0043237)
0.2 7.7 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.2 5.8 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.2 7.7 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.2 6.6 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.2 3.9 GO:0034185 apolipoprotein binding(GO:0034185)
0.1 0.7 GO:0004974 leukotriene receptor activity(GO:0004974)
0.1 1.2 GO:0016679 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.1 3.6 GO:0004697 protein kinase C activity(GO:0004697)
0.1 0.6 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.1 1.0 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.1 2.1 GO:0005537 mannose binding(GO:0005537)
0.1 1.8 GO:0045499 chemorepellent activity(GO:0045499)
0.1 9.4 GO:0015171 amino acid transmembrane transporter activity(GO:0015171)
0.1 1.5 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.8 GO:0004445 inositol-polyphosphate 5-phosphatase activity(GO:0004445) inositol trisphosphate phosphatase activity(GO:0046030)
0.0 1.9 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 0.8 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 7.4 GO:0030674 protein binding, bridging(GO:0030674)
0.0 1.2 GO:0070064 proline-rich region binding(GO:0070064)
0.0 7.2 GO:0004866 endopeptidase inhibitor activity(GO:0004866)
0.0 0.1 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.0 0.6 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 4.4 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.5 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.6 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 24.9 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.2 29.7 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.2 9.9 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.1 9.9 PID IL6 7 PATHWAY IL6-mediated signaling events
0.1 17.2 PID CMYB PATHWAY C-MYB transcription factor network
0.1 7.6 PID FOXO PATHWAY FoxO family signaling
0.1 0.8 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.1 12.6 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 1.7 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 3.5 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.5 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
2.9 23.0 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.8 12.8 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.7 7.7 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.7 20.3 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.7 12.5 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.6 6.5 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.4 8.8 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.3 8.2 REACTOME AMYLOIDS Genes involved in Amyloids
0.2 3.4 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.2 12.2 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.1 7.6 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.1 3.5 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.7 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.0 2.6 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.0 2.1 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 1.9 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.8 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 3.9 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 1.7 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)