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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Zfp105

Z-value: 0.73

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Transcription factors associated with Zfp105

Gene Symbol Gene ID Gene Info
Zfp105
ENSMUSG00000057895.12 Zfp105

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Zfp105mm39_v1_chr9_+_122752116_1227521570.318.3e-03Click!

Activity profile of Zfp105 motif

Sorted Z-values of Zfp105 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Zfp105

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr9_+_75093177 5.29 ENSMUST00000129281.8
ENSMUST00000148144.8
ENSMUST00000130384.2
Myo5a
myosin VA
chr10_-_30647836 4.76 ENSMUST00000215926.2
ENSMUST00000213836.2
Ncoa7
nuclear receptor coactivator 7
chr6_-_142910094 4.50 ENSMUST00000032421.4
St8sia1
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
chr15_-_50753061 3.87 ENSMUST00000165201.9
ENSMUST00000184458.8
Trps1
transcriptional repressor GATA binding 1
chr5_+_86219593 3.64 ENSMUST00000198435.5
ENSMUST00000031171.9
Stap1
signal transducing adaptor family member 1
chr10_-_30647881 3.37 ENSMUST00000215740.2
Ncoa7
nuclear receptor coactivator 7
chr6_+_135339543 3.21 ENSMUST00000205156.3
Emp1
epithelial membrane protein 1
chr6_+_135339929 2.77 ENSMUST00000032330.16
Emp1
epithelial membrane protein 1
chr3_+_63203235 2.56 ENSMUST00000194134.6
Mme
membrane metallo endopeptidase
chr6_+_29859372 2.47 ENSMUST00000115238.10
Ahcyl2
S-adenosylhomocysteine hydrolase-like 2
chr6_-_53797748 2.40 ENSMUST00000127748.5
Tril
TLR4 interactor with leucine-rich repeats
chr2_+_103799873 2.36 ENSMUST00000123437.8
Lmo2
LIM domain only 2
chr15_+_6673167 2.34 ENSMUST00000163073.2
Fyb
FYN binding protein
chr11_+_44508137 2.32 ENSMUST00000109268.2
ENSMUST00000101326.10
ENSMUST00000081265.12
Ebf1
early B cell factor 1
chr10_-_111833138 2.16 ENSMUST00000074805.12
Glipr1
GLI pathogenesis-related 1 (glioma)
chr4_+_74160705 2.11 ENSMUST00000077851.10
Kdm4c
lysine (K)-specific demethylase 4C
chr4_+_101407608 2.04 ENSMUST00000094953.11
ENSMUST00000106933.2
Dnajc6
DnaJ heat shock protein family (Hsp40) member C6
chr3_+_31150982 1.88 ENSMUST00000118204.2
Skil
SKI-like
chr3_+_63203516 1.88 ENSMUST00000029400.7
Mme
membrane metallo endopeptidase
chr5_+_147456497 1.74 ENSMUST00000175807.8
Pan3
PAN3 poly(A) specific ribonuclease subunit
chr15_-_50752437 1.74 ENSMUST00000183997.8
ENSMUST00000183757.8
Trps1
transcriptional repressor GATA binding 1
chr8_+_94537910 1.65 ENSMUST00000138659.9
Gnao1
guanine nucleotide binding protein, alpha O
chr7_-_66915756 1.62 ENSMUST00000207715.2
Mef2a
myocyte enhancer factor 2A
chr10_-_78427721 1.50 ENSMUST00000040580.7
Syde1
synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
chr8_-_57940834 1.32 ENSMUST00000034022.4
Sap30
sin3 associated polypeptide
chr2_+_74534959 1.23 ENSMUST00000151380.2
Hoxd8
homeobox D8
chr5_+_17779273 1.22 ENSMUST00000030568.14
Sema3c
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr6_-_127128007 1.20 ENSMUST00000000188.12
Ccnd2
cyclin D2
chr12_+_3941728 1.20 ENSMUST00000172689.8
ENSMUST00000111186.8
Dnmt3a
DNA methyltransferase 3A
chr6_-_127127959 1.19 ENSMUST00000201637.2
Ccnd2
cyclin D2
chr7_-_15781838 1.19 ENSMUST00000210781.2
Bicra
BRD4 interacting chromatin remodeling complex associated protein
chr6_-_127127993 1.12 ENSMUST00000201066.2
Ccnd2
cyclin D2
chr7_-_79974166 1.09 ENSMUST00000047362.11
ENSMUST00000121882.8
Rccd1
RCC1 domain containing 1
chr18_+_69477541 1.03 ENSMUST00000114985.10
ENSMUST00000128706.8
ENSMUST00000201781.4
ENSMUST00000202674.4
Tcf4
transcription factor 4
chr5_+_146769700 0.98 ENSMUST00000035983.12
Rpl21
ribosomal protein L21
chr6_-_99412306 0.97 ENSMUST00000113322.9
ENSMUST00000176850.8
ENSMUST00000176632.8
Foxp1
forkhead box P1
chr6_+_97968737 0.97 ENSMUST00000043628.13
ENSMUST00000203938.2
Mitf
melanogenesis associated transcription factor
chr15_-_50753437 0.96 ENSMUST00000077935.6
Trps1
transcriptional repressor GATA binding 1
chr6_-_30390996 0.88 ENSMUST00000152391.9
ENSMUST00000115184.2
ENSMUST00000080812.14
ENSMUST00000102992.10
Zc3hc1
zinc finger, C3HC type 1
chr7_-_132724889 0.85 ENSMUST00000166439.8
Ctbp2
C-terminal binding protein 2
chr9_+_57444801 0.84 ENSMUST00000093833.6
ENSMUST00000114200.10
Fam219b
family with sequence similarity 219, member B
chr12_-_52018072 0.82 ENSMUST00000040583.7
Heatr5a
HEAT repeat containing 5A
chr9_+_7692087 0.78 ENSMUST00000018767.8
Mmp7
matrix metallopeptidase 7
chr9_+_108437485 0.73 ENSMUST00000081111.14
ENSMUST00000193421.2
Impdh2
inosine monophosphate dehydrogenase 2
chr5_+_76288524 0.72 ENSMUST00000152642.8
ENSMUST00000127278.8
Srd5a3
steroid 5 alpha-reductase 3
chrX_+_7656225 0.66 ENSMUST00000136930.8
ENSMUST00000115675.9
ENSMUST00000101694.10
Gripap1
GRIP1 associated protein 1
chr9_+_21867043 0.66 ENSMUST00000053583.7
Swsap1
SWIM type zinc finger 7 associated protein 1
chr10_-_23977810 0.64 ENSMUST00000170267.3
Taar8c
trace amine-associated receptor 8C
chr18_+_69633741 0.62 ENSMUST00000207214.2
ENSMUST00000201094.4
ENSMUST00000200703.4
ENSMUST00000202765.4
Tcf4
transcription factor 4
chr11_+_83742961 0.58 ENSMUST00000146786.8
Hnf1b
HNF1 homeobox B
chr5_-_143133260 0.54 ENSMUST00000215102.2
ENSMUST00000213631.2
ENSMUST00000164536.5
Olfr718-ps1
olfactory receptor 718, pseudogene 1
chr6_+_21949986 0.47 ENSMUST00000149728.7
Ing3
inhibitor of growth family, member 3
chr3_+_20043315 0.46 ENSMUST00000173779.2
Cp
ceruloplasmin
chr2_-_151586063 0.45 ENSMUST00000109869.2
Psmf1
proteasome (prosome, macropain) inhibitor subunit 1
chr9_-_117080869 0.44 ENSMUST00000172564.3
Rbms3
RNA binding motif, single stranded interacting protein
chr12_+_87921198 0.33 ENSMUST00000110145.12
ENSMUST00000181843.2
ENSMUST00000180706.8
ENSMUST00000181394.8
ENSMUST00000181326.8
ENSMUST00000181300.2
Gm2042
predicted gene 2042
chr2_-_65397850 0.33 ENSMUST00000238483.2
ENSMUST00000100069.9
Scn3a
sodium channel, voltage-gated, type III, alpha
chr5_+_129875821 0.27 ENSMUST00000171300.8
ENSMUST00000201874.4
Sumf2
sulfatase modifying factor 2
chr7_-_34012934 0.26 ENSMUST00000206399.2
Garre1
granule associated Rac and RHOG effector 1
chr11_+_101623836 0.26 ENSMUST00000129741.2
Dhx8
DEAH (Asp-Glu-Ala-His) box polypeptide 8
chr12_+_103564479 0.25 ENSMUST00000190151.2
Ppp4r4
protein phosphatase 4, regulatory subunit 4
chr11_+_108811168 0.22 ENSMUST00000052915.14
Axin2
axin 2
chr2_+_111329683 0.21 ENSMUST00000219064.3
Olfr1291-ps1
olfactory receptor 1291, pseudogene 1
chr5_+_20112704 0.14 ENSMUST00000115267.7
Magi2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr13_+_67052978 0.13 ENSMUST00000168767.9
Gm10767
predicted gene 10767
chr2_-_87985537 0.11 ENSMUST00000216951.2
Olfr1167
olfactory receptor 1167
chr12_+_87541491 0.06 ENSMUST00000220499.2
Eif1ad12
eukaryotic translation initiation factor 1A domain containing 12
chr14_-_101846551 0.05 ENSMUST00000100340.4
Tbc1d4
TBC1 domain family, member 4
chr11_-_99742434 0.05 ENSMUST00000107437.2
Krtap4-16
keratin associated protein 4-16
chr5_+_20112500 0.02 ENSMUST00000101558.10
Magi2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr16_-_55103598 0.01 ENSMUST00000036412.4
Zpld1
zona pellucida like domain containing 1
chr3_-_116388334 0.00 ENSMUST00000197190.5
ENSMUST00000198454.2
Trmt13
tRNA methyltransferase 13

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.6 GO:1902226 regulation of macrophage colony-stimulating factor signaling pathway(GO:1902226) regulation of response to macrophage colony-stimulating factor(GO:1903969) regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903972)
1.1 5.3 GO:0051643 endoplasmic reticulum localization(GO:0051643)
0.6 4.4 GO:0071492 cellular response to UV-A(GO:0071492)
0.4 8.1 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.3 2.0 GO:0072318 clathrin coat disassembly(GO:0072318)
0.3 1.6 GO:0055005 ventricular cardiac myofibril assembly(GO:0055005)
0.3 1.5 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.3 2.5 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.3 0.8 GO:0002780 antimicrobial peptide biosynthetic process(GO:0002777) antibacterial peptide biosynthetic process(GO:0002780)
0.3 8.4 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.2 3.5 GO:0071481 cellular response to X-ray(GO:0071481)
0.2 6.0 GO:0032060 bleb assembly(GO:0032060)
0.2 0.7 GO:0016095 polyprenol catabolic process(GO:0016095)
0.2 1.2 GO:0003350 pulmonary myocardium development(GO:0003350)
0.2 2.1 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.1 1.7 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.1 0.6 GO:0061296 regulation of pronephros size(GO:0035565) mesonephros morphogenesis(GO:0061206) mesonephric nephron development(GO:0061215) mesonephric nephron morphogenesis(GO:0061228) mesenchymal stem cell maintenance involved in mesonephric nephron morphogenesis(GO:0061235) regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:0061295) negative regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:0061296) mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:1901146)
0.1 2.4 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.1 0.7 GO:0006177 GMP biosynthetic process(GO:0006177)
0.1 1.2 GO:0044027 hypermethylation of CpG island(GO:0044027)
0.1 0.7 GO:1905244 regulation of modification of synaptic structure(GO:1905244)
0.1 0.3 GO:0046684 response to pyrethroid(GO:0046684)
0.1 0.6 GO:0072619 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.1 0.2 GO:0080163 regulation of protein serine/threonine phosphatase activity(GO:0080163)
0.1 1.6 GO:0042118 endothelial cell activation(GO:0042118)
0.1 1.0 GO:0044336 canonical Wnt signaling pathway involved in negative regulation of apoptotic process(GO:0044336)
0.1 4.5 GO:0034605 cellular response to heat(GO:0034605)
0.0 2.4 GO:0034142 toll-like receptor 4 signaling pathway(GO:0034142)
0.0 1.7 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.0 0.3 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.0 2.3 GO:0045576 mast cell activation(GO:0045576)
0.0 0.5 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.9 GO:2001240 negative regulation of signal transduction in absence of ligand(GO:1901099) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.0 0.5 GO:0046688 response to copper ion(GO:0046688)
0.0 0.2 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 5.3 GO:0042642 actomyosin, myosin complex part(GO:0042642)
0.4 3.5 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.3 1.7 GO:0031251 PAN complex(GO:0031251)
0.3 2.4 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.1 0.7 GO:0098837 postsynaptic recycling endosome(GO:0098837)
0.1 0.5 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.1 1.5 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.1 1.3 GO:0016580 Sin3 complex(GO:0016580)
0.1 2.1 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 1.2 GO:0001741 XY body(GO:0001741)
0.0 1.7 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 11.4 GO:0005667 transcription factor complex(GO:0005667)
0.0 4.4 GO:0005903 brush border(GO:0005903)
0.0 1.9 GO:0016605 PML body(GO:0016605)
0.0 0.3 GO:0097470 ribbon synapse(GO:0097470)
0.0 0.7 GO:1990391 DNA repair complex(GO:1990391)
0.0 0.3 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 1.0 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.6 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.7 4.5 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.4 2.5 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.2 4.7 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.2 1.7 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.2 0.7 GO:0047751 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) cholestenone 5-alpha-reductase activity(GO:0047751)
0.1 0.7 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.1 2.1 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.1 1.6 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 1.2 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.1 8.1 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.1 2.3 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.1 1.7 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.1 2.4 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.1 0.6 GO:0001594 trace-amine receptor activity(GO:0001594)
0.1 1.2 GO:0038191 neuropilin binding(GO:0038191)
0.1 3.3 GO:0070888 E-box binding(GO:0070888)
0.0 5.2 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 8.2 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 0.5 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 1.3 GO:0004407 histone deacetylase activity(GO:0004407)
0.0 0.3 GO:0030267 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.0 0.2 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 0.5 GO:0070628 proteasome binding(GO:0070628)
0.0 2.0 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.3 GO:0031402 sodium ion binding(GO:0031402)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.7 PID S1P S1P4 PATHWAY S1P4 pathway
0.1 7.6 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.1 4.6 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.1 3.5 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 3.8 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 2.3 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.0 3.2 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 1.3 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 1.2 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.8 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.2 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.1 2.3 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.1 2.0 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.1 3.5 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.7 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 3.3 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 1.9 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.7 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 1.7 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.0 0.3 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.8 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 2.3 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.5 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters