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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Zfp128

Z-value: 0.73

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Transcription factors associated with Zfp128

Gene Symbol Gene ID Gene Info
Zfp128
ENSMUSG00000060397.7 Zfp128

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Zfp128mm39_v1_chr7_+_12615091_126151320.701.1e-11Click!

Activity profile of Zfp128 motif

Sorted Z-values of Zfp128 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Zfp128

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr4_+_15881256 6.62 ENSMUST00000029876.2
Calb1
calbindin 1
chr2_-_30014538 5.90 ENSMUST00000113677.3
Zer1
zyg-11 related, cell cycle regulator
chr11_+_104441489 5.61 ENSMUST00000018800.9
Myl4
myosin, light polypeptide 4
chr15_-_83949528 5.03 ENSMUST00000156187.8
Efcab6
EF-hand calcium binding domain 6
chr11_+_83599841 4.93 ENSMUST00000001009.14
Wfdc18
WAP four-disulfide core domain 18
chr5_+_144482693 4.65 ENSMUST00000071782.8
Nptx2
neuronal pentraxin 2
chr2_-_30014466 4.56 ENSMUST00000044751.14
Zer1
zyg-11 related, cell cycle regulator
chr9_-_59260713 4.43 ENSMUST00000026265.8
Bbs4
Bardet-Biedl syndrome 4 (human)
chr7_-_79036691 4.12 ENSMUST00000053718.15
ENSMUST00000179243.3
Rlbp1
retinaldehyde binding protein 1
chr8_-_46428277 3.46 ENSMUST00000095323.8
ENSMUST00000098786.3
1700029J07Rik
RIKEN cDNA 1700029J07 gene
chr1_-_194774549 3.36 ENSMUST00000162650.8
Cd46
CD46 antigen, complement regulatory protein
chr17_-_82045800 3.33 ENSMUST00000235015.2
ENSMUST00000163123.3
Slc8a1
solute carrier family 8 (sodium/calcium exchanger), member 1
chr7_-_79036222 2.83 ENSMUST00000205638.2
ENSMUST00000206320.3
ENSMUST00000205442.2
Rlbp1
retinaldehyde binding protein 1
chr12_-_75596441 2.83 ENSMUST00000218716.2
Ppp2r5e
protein phosphatase 2, regulatory subunit B', epsilon
chr14_-_106134253 2.58 ENSMUST00000022709.6
Spry2
sprouty RTK signaling antagonist 2
chr11_-_11920540 2.54 ENSMUST00000109653.8
Grb10
growth factor receptor bound protein 10
chr13_-_59917569 2.27 ENSMUST00000057115.7
Isca1
iron-sulfur cluster assembly 1
chr3_+_97565528 2.26 ENSMUST00000045743.13
Prkab2
protein kinase, AMP-activated, beta 2 non-catalytic subunit
chr19_-_47525437 2.19 ENSMUST00000182808.8
ENSMUST00000182714.2
ENSMUST00000049369.16
Stn1
STN1, CST complex subunit
chr1_+_118409769 2.15 ENSMUST00000191823.6
Clasp1
CLIP associating protein 1
chr7_-_79036654 2.06 ENSMUST00000206695.2
Rlbp1
retinaldehyde binding protein 1
chr7_+_45084257 1.96 ENSMUST00000003964.17
Gys1
glycogen synthase 1, muscle
chr6_-_145156517 1.92 ENSMUST00000111728.8
ENSMUST00000204105.2
ENSMUST00000060797.10
Casc1
cancer susceptibility candidate 1
chr8_-_127672590 1.78 ENSMUST00000179857.3
ENSMUST00000212771.2
Tomm20
translocase of outer mitochondrial membrane 20
chr6_-_118539187 1.75 ENSMUST00000112830.3
Ankrd26
ankyrin repeat domain 26
chr6_-_113478779 1.73 ENSMUST00000101059.4
ENSMUST00000204268.3
ENSMUST00000205170.2
ENSMUST00000205075.2
ENSMUST00000204134.3
Prrt3
proline-rich transmembrane protein 3
chr15_-_96540760 1.66 ENSMUST00000088452.11
Slc38a1
solute carrier family 38, member 1
chr9_+_3335135 1.50 ENSMUST00000212294.2
Alkbh8
alkB homolog 8, tRNA methyltransferase
chr3_+_135053762 1.49 ENSMUST00000159658.8
ENSMUST00000078568.12
Slc9b1
solute carrier family 9, subfamily B (NHA1, cation proton antiporter 1), member 1
chr7_+_45084300 1.48 ENSMUST00000211150.2
Gys1
glycogen synthase 1, muscle
chr7_+_45175754 1.48 ENSMUST00000211227.2
ENSMUST00000051810.15
Plekha4
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4
chr7_+_23811739 1.44 ENSMUST00000120006.8
ENSMUST00000005413.4
Zfp112
zinc finger protein 112
chr9_+_3335469 1.37 ENSMUST00000053407.13
ENSMUST00000211933.2
ENSMUST00000212666.2
Alkbh8
alkB homolog 8, tRNA methyltransferase
chr4_+_126450728 1.34 ENSMUST00000048391.15
Clspn
claspin
chr6_+_17281184 1.32 ENSMUST00000000058.7
Cav2
caveolin 2
chr5_-_138169253 1.26 ENSMUST00000139983.8
Mcm7
minichromosome maintenance complex component 7
chr9_+_111268131 1.22 ENSMUST00000111879.5
Dclk3
doublecortin-like kinase 3
chr17_+_34062059 1.17 ENSMUST00000002379.15
Cd320
CD320 antigen
chr7_-_44578834 1.16 ENSMUST00000107857.11
ENSMUST00000167930.8
ENSMUST00000085399.13
ENSMUST00000166972.9
Ap2a1
adaptor-related protein complex 2, alpha 1 subunit
chr5_-_138169509 1.04 ENSMUST00000153867.8
Mcm7
minichromosome maintenance complex component 7
chr4_+_138960687 1.03 ENSMUST00000042675.9
Capzb
capping protein (actin filament) muscle Z-line, beta
chr3_+_37474422 0.95 ENSMUST00000029277.13
ENSMUST00000198968.2
Spata5
spermatogenesis associated 5
chr5_-_138169476 0.93 ENSMUST00000147920.2
Mcm7
minichromosome maintenance complex component 7
chr7_-_45084012 0.89 ENSMUST00000107771.12
ENSMUST00000211666.2
Ruvbl2
RuvB-like protein 2
chr9_+_3335507 0.88 ENSMUST00000212154.2
Alkbh8
alkB homolog 8, tRNA methyltransferase
chr5_+_137759934 0.88 ENSMUST00000110983.3
ENSMUST00000031738.5
Tsc22d4
TSC22 domain family, member 4
chr18_-_37777238 0.83 ENSMUST00000066272.6
Taf7
TATA-box binding protein associated factor 7
chr2_-_70885877 0.77 ENSMUST00000090849.6
ENSMUST00000100037.9
ENSMUST00000112186.9
Mettl8
methyltransferase like 8
chr7_-_45175570 0.61 ENSMUST00000167273.2
ENSMUST00000042105.11
Ppp1r15a
protein phosphatase 1, regulatory subunit 15A
chr16_+_8500694 0.56 ENSMUST00000202157.2
Gm5767
predicted gene 5767
chr9_+_21323120 0.53 ENSMUST00000002902.8
Qtrt1
queuine tRNA-ribosyltransferase catalytic subunit 1
chr6_-_54969928 0.53 ENSMUST00000131475.2
Ggct
gamma-glutamyl cyclotransferase
chr4_+_126450762 0.45 ENSMUST00000147675.2
Clspn
claspin
chr15_+_76763431 0.44 ENSMUST00000023179.7
Zfp7
zinc finger protein 7
chr6_-_128339775 0.40 ENSMUST00000112152.8
ENSMUST00000057421.15
ENSMUST00000112151.2
Rhno1
RAD9-HUS1-RAD1 interacting nuclear orphan 1
chr6_-_128339458 0.39 ENSMUST00000155573.3
Rhno1
RAD9-HUS1-RAD1 interacting nuclear orphan 1
chr5_-_121329385 0.36 ENSMUST00000054547.9
ENSMUST00000100770.9
Ptpn11
protein tyrosine phosphatase, non-receptor type 11
chr15_+_76211597 0.23 ENSMUST00000059045.8
Exosc4
exosome component 4
chr6_-_54969843 0.22 ENSMUST00000203208.2
Ggct
gamma-glutamyl cyclotransferase
chr6_+_128339882 0.22 ENSMUST00000073316.13
Foxm1
forkhead box M1
chr11_-_116164928 0.21 ENSMUST00000106425.4
Srp68
signal recognition particle 68
chr13_+_67080864 0.16 ENSMUST00000021990.4
Ptdss1
phosphatidylserine synthase 1
chr11_-_116165024 0.15 ENSMUST00000021133.16
Srp68
signal recognition particle 68
chr11_+_9141934 0.12 ENSMUST00000042740.13
Abca13
ATP-binding cassette, sub-family A (ABC1), member 13
chr15_-_76554065 0.10 ENSMUST00000037824.6
Foxh1
forkhead box H1
chr3_+_145926709 0.09 ENSMUST00000039164.4
Lpar3
lysophosphatidic acid receptor 3

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 6.6 GO:0035502 metanephric part of ureteric bud development(GO:0035502)
1.1 3.4 GO:0043382 positive regulation of memory T cell differentiation(GO:0043382)
1.1 4.4 GO:0038108 negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108)
0.4 2.6 GO:0051387 negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.4 1.2 GO:1900126 negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.4 3.7 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.4 3.3 GO:0098735 cellular response to caffeine(GO:0071313) positive regulation of the force of heart contraction(GO:0098735)
0.4 1.8 GO:0035927 RNA import into mitochondrion(GO:0035927)
0.3 2.3 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.3 3.2 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.3 2.5 GO:0045719 negative regulation of glycogen biosynthetic process(GO:0045719)
0.2 1.7 GO:0006868 glutamine transport(GO:0006868)
0.2 2.1 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.2 0.6 GO:0060734 regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:0060734)
0.2 1.8 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.2 1.2 GO:0015889 cobalamin transport(GO:0015889)
0.2 1.3 GO:0060161 positive regulation of dopamine receptor signaling pathway(GO:0060161)
0.1 0.9 GO:0071898 regulation of estrogen receptor binding(GO:0071898) negative regulation of estrogen receptor binding(GO:0071899)
0.1 10.5 GO:0051438 regulation of ubiquitin-protein transferase activity(GO:0051438)
0.1 5.6 GO:0002026 regulation of the force of heart contraction(GO:0002026)
0.1 0.4 GO:2000850 negative regulation of corticosteroid hormone secretion(GO:2000847) negative regulation of glucocorticoid secretion(GO:2000850)
0.1 0.9 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.1 2.2 GO:0032211 negative regulation of telomere maintenance via telomerase(GO:0032211)
0.1 1.0 GO:0051490 negative regulation of filopodium assembly(GO:0051490)
0.1 0.8 GO:0080009 mRNA methylation(GO:0080009)
0.1 1.8 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 0.2 GO:0071051 polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.0 8.2 GO:0007601 visual perception(GO:0007601)
0.0 2.8 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0 4.7 GO:0008306 associative learning(GO:0008306)
0.0 0.8 GO:0035067 negative regulation of histone acetylation(GO:0035067)
0.0 0.1 GO:2000823 regulation of androgen receptor activity(GO:2000823)
0.0 0.4 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 0.2 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.0 0.2 GO:0090344 negative regulation of cell aging(GO:0090344)
0.0 4.9 GO:0010466 negative regulation of peptidase activity(GO:0010466)
0.0 1.5 GO:0030317 sperm motility(GO:0030317)
0.0 2.3 GO:0006633 fatty acid biosynthetic process(GO:0006633)
0.0 1.2 GO:1900181 negative regulation of protein localization to nucleus(GO:1900181)
0.0 0.8 GO:0001836 release of cytochrome c from mitochondria(GO:0001836)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.2 GO:1990879 CST complex(GO:1990879)
0.7 3.4 GO:0002079 inner acrosomal membrane(GO:0002079)
0.7 10.5 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.3 4.4 GO:0034464 BBSome(GO:0034464)
0.3 2.1 GO:0005828 kinetochore microtubule(GO:0005828)
0.2 3.2 GO:0042555 MCM complex(GO:0042555)
0.1 1.8 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.1 2.3 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 0.9 GO:0097255 R2TP complex(GO:0097255)
0.1 2.8 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 1.0 GO:0071203 WASH complex(GO:0071203)
0.1 0.8 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.1 5.2 GO:0031672 A band(GO:0031672)
0.0 1.3 GO:0002080 acrosomal membrane(GO:0002080)
0.0 1.2 GO:0032433 filopodium tip(GO:0032433)
0.0 0.6 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.4 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.0 6.6 GO:0043195 terminal bouton(GO:0043195)
0.0 1.5 GO:0097228 sperm principal piece(GO:0097228)
0.0 3.3 GO:0014704 intercalated disc(GO:0014704)
0.0 3.4 GO:0016234 inclusion body(GO:0016234)
0.0 0.2 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.1 GO:0032444 activin responsive factor complex(GO:0032444)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 9.0 GO:0005502 11-cis retinal binding(GO:0005502)
1.1 3.4 GO:0004373 glycogen (starch) synthase activity(GO:0004373)
1.1 3.3 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.8 6.6 GO:0005499 vitamin D binding(GO:0005499)
0.6 3.7 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.6 1.8 GO:0030943 mitochondrion targeting sequence binding(GO:0030943)
0.5 4.4 GO:0034452 dynactin binding(GO:0034452)
0.3 2.1 GO:0043515 kinetochore binding(GO:0043515)
0.3 1.8 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.2 1.7 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.2 0.8 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
0.1 2.2 GO:0043047 single-stranded telomeric DNA binding(GO:0043047)
0.1 0.8 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.1 3.4 GO:0001848 complement binding(GO:0001848)
0.1 5.6 GO:0003785 actin monomer binding(GO:0003785)
0.1 0.9 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.1 1.2 GO:0031419 cobalamin binding(GO:0031419)
0.1 2.3 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.1 3.2 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.1 1.5 GO:0015299 solute:proton antiporter activity(GO:0015299)
0.1 2.3 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.1 0.8 GO:0008174 mRNA methyltransferase activity(GO:0008174)
0.1 0.4 GO:0005047 signal recognition particle binding(GO:0005047) endoplasmic reticulum signal peptide binding(GO:0030942)
0.1 0.5 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.1 2.6 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.1 1.7 GO:0031748 D1 dopamine receptor binding(GO:0031748)
0.0 2.5 GO:0005158 insulin receptor binding(GO:0005158)
0.0 2.9 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 3.4 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 1.5 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 1.2 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.0 4.9 GO:0030414 peptidase inhibitor activity(GO:0030414)
0.0 9.8 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 4.7 GO:0030246 carbohydrate binding(GO:0030246)
0.0 0.1 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 5.0 PID ATR PATHWAY ATR signaling pathway
0.1 2.8 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 2.9 PID IGF1 PATHWAY IGF1 pathway
0.0 1.2 PID ARF 3PATHWAY Arf1 pathway
0.0 2.6 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 1.3 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 0.9 PID MYC PATHWAY C-MYC pathway
0.0 0.6 PID BMP PATHWAY BMP receptor signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.4 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.2 3.2 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.2 2.3 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.2 2.5 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.1 3.3 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.1 2.8 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.1 2.6 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.1 5.6 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 1.2 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 2.1 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 3.4 REACTOME GLUCOSE METABOLISM Genes involved in Glucose metabolism
0.0 1.8 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 1.7 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.9 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.0 0.6 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.8 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation