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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Zfp423

Z-value: 0.40

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Transcription factors associated with Zfp423

Gene Symbol Gene ID Gene Info
Zfp423
ENSMUSG00000045333.16 Zfp423

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Zfp423mm39_v1_chr8_-_88686188_886862230.262.7e-02Click!

Activity profile of Zfp423 motif

Sorted Z-values of Zfp423 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Zfp423

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr2_-_29142965 2.78 ENSMUST00000155949.2
ENSMUST00000154682.8
ENSMUST00000028141.6
ENSMUST00000071201.5
6530402F18Rik
Ntng2
RIKEN cDNA 6530402F18 gene
netrin G2
chr9_-_37464200 2.64 ENSMUST00000065668.12
Nrgn
neurogranin
chr16_+_17307503 2.28 ENSMUST00000023448.15
Aifm3
apoptosis-inducing factor, mitochondrion-associated 3
chr15_-_66158445 1.93 ENSMUST00000070256.9
Kcnq3
potassium voltage-gated channel, subfamily Q, member 3
chr11_+_87469211 1.69 ENSMUST00000107962.8
ENSMUST00000122067.8
Septin4
septin 4
chr3_+_114697710 1.60 ENSMUST00000081752.13
Olfm3
olfactomedin 3
chr4_+_42917228 1.56 ENSMUST00000107976.9
ENSMUST00000069184.9
Phf24
PHD finger protein 24
chr12_+_102915102 1.50 ENSMUST00000101099.12
Unc79
unc-79 homolog
chr19_-_10847121 1.37 ENSMUST00000120524.2
ENSMUST00000025645.14
Tmem132a
transmembrane protein 132A
chr18_+_40390013 1.32 ENSMUST00000096572.2
ENSMUST00000236889.2
Kctd16
potassium channel tetramerisation domain containing 16
chr6_+_110622533 1.27 ENSMUST00000071076.13
ENSMUST00000172951.2
Grm7
glutamate receptor, metabotropic 7
chr17_+_69463786 1.27 ENSMUST00000112680.8
ENSMUST00000080208.7
ENSMUST00000225977.2
Epb41l3
erythrocyte membrane protein band 4.1 like 3
chr2_+_38229270 1.24 ENSMUST00000143783.9
Lhx2
LIM homeobox protein 2
chr8_+_59365291 1.16 ENSMUST00000160055.2
BC030500
cDNA sequence BC030500
chr15_-_78602313 1.07 ENSMUST00000229441.2
Elfn2
leucine rich repeat and fibronectin type III, extracellular 2
chr10_+_60185093 0.96 ENSMUST00000105459.2
Vsir
V-set immunoregulatory receptor
chr19_+_6451667 0.91 ENSMUST00000113471.3
ENSMUST00000113469.3
Rasgrp2
RAS, guanyl releasing protein 2
chr2_+_106523532 0.87 ENSMUST00000111063.8
Mpped2
metallophosphoesterase domain containing 2
chr19_-_10079091 0.86 ENSMUST00000025567.9
Fads2
fatty acid desaturase 2
chr7_+_29007349 0.86 ENSMUST00000108230.8
ENSMUST00000065181.12
Dpf1
D4, zinc and double PHD fingers family 1
chrX_-_74174608 0.85 ENSMUST00000033775.9
Mpp1
membrane protein, palmitoylated
chr11_+_54793569 0.83 ENSMUST00000082430.11
Gpx3
glutathione peroxidase 3
chr7_+_30121147 0.78 ENSMUST00000108176.9
Nfkbid
nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, delta
chr4_+_129407374 0.73 ENSMUST00000062356.7
Marcksl1
MARCKS-like 1
chr9_+_120321557 0.72 ENSMUST00000007139.6
Eif1b
eukaryotic translation initiation factor 1B
chr17_+_69463846 0.72 ENSMUST00000238898.2
Epb41l3
erythrocyte membrane protein band 4.1 like 3
chr2_+_180141686 0.68 ENSMUST00000029084.9
Ntsr1
neurotensin receptor 1
chr5_+_88712840 0.66 ENSMUST00000196894.5
ENSMUST00000198965.5
Rufy3
RUN and FYVE domain containing 3
chr17_-_11059172 0.62 ENSMUST00000041463.7
Pacrg
PARK2 co-regulated
chr19_+_7245591 0.62 ENSMUST00000066646.12
Rcor2
REST corepressor 2
chrX_-_74174450 0.58 ENSMUST00000114092.8
ENSMUST00000132501.8
ENSMUST00000153318.8
ENSMUST00000155742.2
Mpp1
membrane protein, palmitoylated
chr11_+_11065782 0.57 ENSMUST00000056344.5
Vwc2
von Willebrand factor C domain containing 2
chr12_+_109425769 0.57 ENSMUST00000173812.2
Dlk1
delta like non-canonical Notch ligand 1
chr5_-_24628514 0.52 ENSMUST00000030814.11
Cdk5
cyclin-dependent kinase 5
chrX_-_74174524 0.52 ENSMUST00000114091.8
Mpp1
membrane protein, palmitoylated
chr17_-_23864237 0.51 ENSMUST00000024696.9
Mmp25
matrix metallopeptidase 25
chr11_+_54793743 0.50 ENSMUST00000149324.3
Gpx3
glutathione peroxidase 3
chr10_+_14581325 0.50 ENSMUST00000191238.7
ENSMUST00000190114.2
Nmbr
neuromedin B receptor
chr19_+_10019023 0.49 ENSMUST00000237672.2
Fads3
fatty acid desaturase 3
chr15_-_103242697 0.47 ENSMUST00000229373.2
Zfp385a
zinc finger protein 385A
chr2_-_30249202 0.44 ENSMUST00000100215.11
ENSMUST00000113620.10
ENSMUST00000163668.3
ENSMUST00000028214.15
ENSMUST00000113621.10
Sh3glb2
SH3-domain GRB2-like endophilin B2
chr15_+_78128990 0.43 ENSMUST00000096357.12
Ncf4
neutrophil cytosolic factor 4
chrX_+_7688528 0.41 ENSMUST00000009875.5
Kcnd1
potassium voltage-gated channel, Shal-related family, member 1
chr5_-_24628483 0.40 ENSMUST00000198990.2
Cdk5
cyclin-dependent kinase 5
chr10_+_80972089 0.40 ENSMUST00000048128.15
Zbtb7a
zinc finger and BTB domain containing 7a
chr10_-_61946724 0.39 ENSMUST00000142821.8
ENSMUST00000124615.8
ENSMUST00000064050.5
ENSMUST00000125704.8
ENSMUST00000142796.8
Fam241b
family with sequence similarity 241, member B
chr16_+_49675969 0.37 ENSMUST00000229101.2
ENSMUST00000230836.2
ENSMUST00000229206.2
ENSMUST00000084838.14
ENSMUST00000230281.2
Cd47
CD47 antigen (Rh-related antigen, integrin-associated signal transducer)
chr8_-_84425724 0.37 ENSMUST00000005616.16
Pkn1
protein kinase N1
chr12_-_14202041 0.36 ENSMUST00000020926.8
Lratd1
LRAT domain containing 1
chr15_+_78129040 0.35 ENSMUST00000133618.3
Ncf4
neutrophil cytosolic factor 4
chr7_-_45519853 0.32 ENSMUST00000211713.2
Grin2d
glutamate receptor, ionotropic, NMDA2D (epsilon 4)
chr2_+_93017887 0.31 ENSMUST00000150462.8
ENSMUST00000111266.8
Trp53i11
transformation related protein 53 inducible protein 11
chr2_+_93017916 0.30 ENSMUST00000090554.11
Trp53i11
transformation related protein 53 inducible protein 11
chr7_+_127084283 0.29 ENSMUST00000048896.8
Fbrs
fibrosin
chr19_-_5781503 0.29 ENSMUST00000162976.2
Znrd2
zinc ribbon domain containing 2
chr9_+_57037974 0.28 ENSMUST00000160147.8
ENSMUST00000161663.8
ENSMUST00000034836.16
ENSMUST00000161182.8
Man2c1
mannosidase, alpha, class 2C, member 1
chr10_-_14581203 0.28 ENSMUST00000149485.2
ENSMUST00000154132.8
Vta1
vesicle (multivesicular body) trafficking 1
chr5_-_135963408 0.26 ENSMUST00000198270.2
ENSMUST00000055808.6
Ywhag
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide
chr4_+_126915104 0.25 ENSMUST00000030623.8
Sfpq
splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated)
chr18_+_34892599 0.25 ENSMUST00000097622.4
Fam53c
family with sequence similarity 53, member C
chr1_+_156386414 0.24 ENSMUST00000166172.9
ENSMUST00000027888.13
Abl2
v-abl Abelson murine leukemia viral oncogene 2 (arg, Abelson-related gene)
chr17_-_23939700 0.24 ENSMUST00000201734.4
1520401A03Rik
RIKEN cDNA 1520401A03 gene
chr5_+_67418137 0.21 ENSMUST00000161369.3
Tmem33
transmembrane protein 33
chr4_-_148711453 0.21 ENSMUST00000165113.8
ENSMUST00000172073.8
ENSMUST00000105702.9
ENSMUST00000084125.10
Tardbp
TAR DNA binding protein
chr11_-_99228756 0.21 ENSMUST00000100482.3
Krt26
keratin 26
chr19_+_10018914 0.21 ENSMUST00000115995.4
Fads3
fatty acid desaturase 3
chr7_-_19192672 0.20 ENSMUST00000239292.2
ENSMUST00000085715.7
Mark4
MAP/microtubule affinity regulating kinase 4
chr4_-_116982804 0.20 ENSMUST00000183310.2
Btbd19
BTB (POZ) domain containing 19
chr8_-_120904179 0.18 ENSMUST00000048786.13
Cibar2
CBY1 interacting BAR domain containing 2
chr7_-_128062916 0.18 ENSMUST00000205835.2
Tial1
Tia1 cytotoxic granule-associated RNA binding protein-like 1
chr2_+_164627913 0.16 ENSMUST00000152471.2
Snx21
sorting nexin family member 21
chr2_+_164627743 0.16 ENSMUST00000174070.8
ENSMUST00000172577.8
ENSMUST00000056181.7
Snx21
sorting nexin family member 21
chr19_+_41818409 0.14 ENSMUST00000087155.5
Frat1
frequently rearranged in advanced T cell lymphomas
chr13_+_41403317 0.14 ENSMUST00000165561.4
Smim13
small integral membrane protein 13
chr17_+_11059248 0.12 ENSMUST00000191124.7
Prkn
parkin RBR E3 ubiquitin protein ligase
chr11_+_102727122 0.10 ENSMUST00000021302.15
ENSMUST00000107072.2
Higd1b
HIG1 domain family, member 1B
chr6_-_124391994 0.10 ENSMUST00000035861.6
ENSMUST00000112532.8
ENSMUST00000080557.12
Pex5
peroxisomal biogenesis factor 5
chr4_-_148711211 0.10 ENSMUST00000186947.7
ENSMUST00000105699.8
Tardbp
TAR DNA binding protein
chr3_+_94882038 0.08 ENSMUST00000072287.12
Pi4kb
phosphatidylinositol 4-kinase beta
chr7_+_18737944 0.08 ENSMUST00000053713.5
Irf2bp1
interferon regulatory factor 2 binding protein 1
chr17_-_25652750 0.07 ENSMUST00000159610.8
ENSMUST00000159048.8
ENSMUST00000078496.12
Cacna1h
calcium channel, voltage-dependent, T type, alpha 1H subunit
chr7_-_79443536 0.05 ENSMUST00000032760.6
Mesp1
mesoderm posterior 1
chr7_-_25454177 0.05 ENSMUST00000206832.2
Hnrnpul1
heterogeneous nuclear ribonucleoprotein U-like 1
chr9_-_99758200 0.03 ENSMUST00000054819.10
Sox14
SRY (sex determining region Y)-box 14
chrX_+_57076359 0.01 ENSMUST00000088631.11
ENSMUST00000088629.4
Zic3
zinc finger protein of the cerebellum 3
chr15_-_98676007 0.00 ENSMUST00000226655.2
ENSMUST00000228546.2
ENSMUST00000023732.12
ENSMUST00000226610.2
Wnt10b
wingless-type MMTV integration site family, member 10B

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.3 GO:0001661 conditioned taste aversion(GO:0001661)
0.2 2.0 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.1 1.0 GO:2000562 negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562)
0.1 0.5 GO:0010609 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.1 0.7 GO:0070777 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779) positive regulation of arachidonic acid secretion(GO:0090238)
0.1 0.9 GO:0046826 negative regulation of protein export from nucleus(GO:0046826)
0.1 1.9 GO:0060081 membrane hyperpolarization(GO:0060081)
0.1 1.5 GO:0048149 behavioral response to ethanol(GO:0048149)
0.1 0.2 GO:1903896 positive regulation of IRE1-mediated unfolded protein response(GO:1903896)
0.1 1.2 GO:0045199 maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.1 0.8 GO:0070245 positive regulation of thymocyte apoptotic process(GO:0070245)
0.1 0.5 GO:0060022 hard palate development(GO:0060022)
0.1 2.2 GO:1900273 positive regulation of long-term synaptic potentiation(GO:1900273)
0.1 1.9 GO:0050966 detection of mechanical stimulus involved in sensory perception of pain(GO:0050966)
0.0 2.0 GO:0090022 regulation of neutrophil chemotaxis(GO:0090022)
0.0 0.4 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.0 0.3 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.0 1.3 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.0 0.1 GO:0016561 protein import into peroxisome matrix, translocation(GO:0016561)
0.0 0.4 GO:0008228 opsonization(GO:0008228)
0.0 0.3 GO:1902177 positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902177)
0.0 0.3 GO:0071763 nuclear membrane organization(GO:0071763)
0.0 0.3 GO:0006013 mannose metabolic process(GO:0006013)
0.0 0.8 GO:0045730 respiratory burst(GO:0045730)
0.0 0.7 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.0 2.3 GO:0097194 execution phase of apoptosis(GO:0097194)
0.0 1.3 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.0 0.1 GO:0090081 regulation of heart induction by regulation of canonical Wnt signaling pathway(GO:0090081)
0.0 0.2 GO:0006930 substrate-dependent cell migration, cell extension(GO:0006930)
0.0 0.6 GO:0045780 positive regulation of bone resorption(GO:0045780) positive regulation of bone remodeling(GO:0046852)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.2 2.6 GO:0044327 dendritic spine head(GO:0044327)
0.2 0.7 GO:0032280 symmetric synapse(GO:0032280)
0.1 1.3 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.1 2.0 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.1 2.2 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.8 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 1.9 GO:0033268 node of Ranvier(GO:0033268)
0.0 2.8 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.7 GO:0071437 invadopodium(GO:0071437)
0.0 0.9 GO:0071565 nBAF complex(GO:0071565)
0.0 0.3 GO:0042382 paraspeckles(GO:0042382)
0.0 0.6 GO:0097225 sperm midpiece(GO:0097225)
0.0 1.3 GO:0042734 presynaptic membrane(GO:0042734)
0.0 0.3 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:0070905 serine binding(GO:0070905)
0.2 0.7 GO:0016492 G-protein coupled neurotensin receptor activity(GO:0016492)
0.2 0.5 GO:0004946 bombesin receptor activity(GO:0004946)
0.1 0.9 GO:0030549 acetylcholine receptor activator activity(GO:0030549)
0.1 0.9 GO:0004768 stearoyl-CoA 9-desaturase activity(GO:0004768)
0.1 0.4 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.1 2.6 GO:0070300 phosphatidic acid binding(GO:0070300)
0.1 0.4 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.1 1.3 GO:0008430 selenium binding(GO:0008430)
0.1 2.3 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.1 0.8 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.4 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.0 0.3 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 1.1 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.1 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.0 0.1 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 0.8 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 1.9 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.0 0.3 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.0 2.0 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.2 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.6 GO:0043014 alpha-tubulin binding(GO:0043014)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.8 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.4 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.9 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 0.9 PID RAS PATHWAY Regulation of Ras family activation

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.9 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 1.9 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.9 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.9 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.5 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.8 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 0.6 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.4 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions