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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Zic3

Z-value: 1.02

Motif logo

Transcription factors associated with Zic3

Gene Symbol Gene ID Gene Info
ENSMUSG00000067860.12 Zic3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Zic3mm39_v1_chrX_+_57076359_57076378-0.334.7e-03Click!

Activity profile of Zic3 motif

Sorted Z-values of Zic3 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Zic3

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr10_+_87357657 9.99 ENSMUST00000020241.17
phenylalanine hydroxylase
chr10_+_87357782 9.36 ENSMUST00000219813.2
phenylalanine hydroxylase
chr10_+_87357816 9.10 ENSMUST00000218573.2
phenylalanine hydroxylase
chr7_+_51528715 7.49 ENSMUST00000051912.13
growth arrest specific 2
chr7_+_51528788 6.44 ENSMUST00000107591.9
growth arrest specific 2
chr11_-_75329726 5.84 ENSMUST00000108437.8
serine (or cysteine) peptidase inhibitor, clade F, member 2
chr4_+_108022645 5.11 ENSMUST00000116309.10
ENSMUST00000116307.8
enoyl Coenzyme A hydratase domain containing 2
chr4_+_108022628 5.00 ENSMUST00000052999.13
enoyl Coenzyme A hydratase domain containing 2
chr12_-_103739847 4.75 ENSMUST00000078869.6
serine (or cysteine) peptidase inhibitor, clade A, member 1D
chr15_-_78687216 4.64 ENSMUST00000164826.8
caspase recruitment domain family, member 10
chr7_+_127399789 4.34 ENSMUST00000125188.8
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7
chr2_+_31840340 4.23 ENSMUST00000148056.4
allograft inflammatory factor 1-like
chr2_+_31840151 4.18 ENSMUST00000001920.13
ENSMUST00000151276.3
allograft inflammatory factor 1-like
chr7_+_127399776 4.04 ENSMUST00000046863.12
ENSMUST00000206674.2
ENSMUST00000106272.8
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7
chr8_+_127790772 3.93 ENSMUST00000079777.12
ENSMUST00000160272.8
ENSMUST00000162907.8
ENSMUST00000162536.8
ENSMUST00000026921.13
ENSMUST00000162665.8
ENSMUST00000162602.8
ENSMUST00000160581.8
ENSMUST00000161355.8
ENSMUST00000162531.8
ENSMUST00000160766.8
ENSMUST00000159537.8
par-3 family cell polarity regulator
chr3_+_14545751 3.85 ENSMUST00000037321.8
ENSMUST00000120484.8
ENSMUST00000120801.2
solute carrier family 7 (cationic amino acid transporter, y+ system), member 12
chr1_+_192835414 3.85 ENSMUST00000076521.7
interferon regulatory factor 6
chr7_+_127399848 3.84 ENSMUST00000139068.8
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7
chr14_-_31362909 3.51 ENSMUST00000022437.16
2-hydroxyacyl-CoA lyase 1
chr14_-_31362835 3.50 ENSMUST00000167066.8
ENSMUST00000127204.9
2-hydroxyacyl-CoA lyase 1
chr2_+_91087668 3.44 ENSMUST00000111349.9
ENSMUST00000131711.8
protein kinase C and casein kinase substrate in neurons 3
chr11_-_70120503 3.44 ENSMUST00000153449.2
ENSMUST00000000326.12
B cell CLL/lymphoma 6, member B
chr6_-_52211882 3.34 ENSMUST00000125581.2
homeobox A10
chr3_+_118355778 3.33 ENSMUST00000039177.12
dihydropyrimidine dehydrogenase
chr14_-_30665232 3.29 ENSMUST00000006704.17
ENSMUST00000163118.2
inter-alpha trypsin inhibitor, heavy chain 1
chr2_-_170339061 3.28 ENSMUST00000038824.6
cytochrome P450, family 24, subfamily a, polypeptide 1
chr4_-_106349480 3.03 ENSMUST00000054472.4
barttin CLCNK type accessory beta subunit
chr15_+_7159038 2.99 ENSMUST00000067190.12
ENSMUST00000164529.9
LIF receptor alpha
chr2_+_70305267 2.97 ENSMUST00000100043.3
trans-acting transcription factor 5
chr10_-_127358231 2.97 ENSMUST00000219239.2
serine hydroxymethyltransferase 2 (mitochondrial)
chr6_-_52168675 2.90 ENSMUST00000101395.3
homeobox A4
chr14_+_33662976 2.82 ENSMUST00000100720.2
growth differentiation factor 2
chr2_+_124994425 2.81 ENSMUST00000110494.9
ENSMUST00000110495.3
ENSMUST00000028630.9
solute carrier family 12, member 1
chr10_-_127358300 2.79 ENSMUST00000026470.6
serine hydroxymethyltransferase 2 (mitochondrial)
chr2_+_78699360 2.77 ENSMUST00000028398.14
ubiquitin-conjugating enzyme E2E 3
chr11_-_7163897 2.72 ENSMUST00000020702.11
ENSMUST00000135887.3
insulin-like growth factor binding protein 3
chr6_+_24597724 2.72 ENSMUST00000031694.8
leiomodin 2 (cardiac)
chr9_-_96900876 2.66 ENSMUST00000055433.5
splA/ryanodine receptor domain and SOCS box containing 4
chr8_+_120163857 2.63 ENSMUST00000152420.8
ENSMUST00000212112.2
ENSMUST00000098365.4
oxidative stress induced growth inhibitor 1
chr9_-_50663571 2.60 ENSMUST00000042790.5
heat shock protein 2
chr14_+_34097422 2.48 ENSMUST00000111908.3
multimerin 2
chr11_+_96920956 2.45 ENSMUST00000153482.2
secernin 2
chr19_+_56862681 2.43 ENSMUST00000026068.8
von Willebrand factor A domain containing 2
chr10_-_107321938 2.41 ENSMUST00000000445.2
myogenic factor 5
chr9_+_50663171 2.39 ENSMUST00000214609.2
crystallin, alpha B
chr11_+_96920751 2.39 ENSMUST00000021249.11
secernin 2
chr10_-_95159933 2.33 ENSMUST00000053594.7
CASP2 and RIPK1 domain containing adaptor with death domain
chr3_+_118355811 2.30 ENSMUST00000149101.3
dihydropyrimidine dehydrogenase
chr16_-_30086317 2.19 ENSMUST00000064856.9
carboxypeptidase N, polypeptide 2
chr12_-_69771604 2.19 ENSMUST00000021370.10
L-2-hydroxyglutarate dehydrogenase
chr14_-_64654397 2.12 ENSMUST00000210428.2
methionine sulfoxide reductase A
chr13_+_74269554 2.07 ENSMUST00000036208.7
ENSMUST00000225423.2
ENSMUST00000221703.2
solute carrier family 9 (sodium/hydrogen exchanger), member 3
chr6_+_82029288 2.05 ENSMUST00000149023.2
eva-1 homolog A (C. elegans)
chr14_+_31363004 2.04 ENSMUST00000090147.7
biotinidase
chr1_-_105284383 2.02 ENSMUST00000058688.7
ring finger protein 152
chr13_-_25121568 2.00 ENSMUST00000037615.7
aldhehyde dehydrogenase family 5, subfamily A1
chr11_+_69729340 1.98 ENSMUST00000133967.8
ENSMUST00000094065.5
transmembrane protein 256
chr7_+_28524627 1.97 ENSMUST00000066264.13
enoyl coenzyme A hydratase 1, peroxisomal
chr12_-_119202527 1.96 ENSMUST00000026360.9
integrin beta 8
chr7_+_100966289 1.96 ENSMUST00000163799.9
ENSMUST00000164479.9
START domain containing 10
chr11_+_3981769 1.95 ENSMUST00000019512.8
SEC14-like lipid binding 4
chr9_+_44584523 1.93 ENSMUST00000034609.11
ENSMUST00000071219.12
trehalase (brush-border membrane glycoprotein)
chr11_-_70590923 1.93 ENSMUST00000108543.4
ENSMUST00000108542.8
ENSMUST00000108541.9
ENSMUST00000126114.9
ENSMUST00000073625.8
inhibitor of CDK, cyclin A1 interacting protein 1
chr19_-_4889284 1.90 ENSMUST00000236451.2
ENSMUST00000236178.2
copper chaperone for superoxide dismutase
chr3_-_57483330 1.89 ENSMUST00000120977.2
WW domain containing transcription regulator 1
chr15_-_89310060 1.89 ENSMUST00000109313.9
carnitine palmitoyltransferase 1b, muscle
chr1_-_105284407 1.88 ENSMUST00000172299.2
ring finger protein 152
chr1_-_132067404 1.87 ENSMUST00000027697.12
cyclin-dependent kinase 18
chr19_-_4889314 1.85 ENSMUST00000235245.2
ENSMUST00000037246.7
copper chaperone for superoxide dismutase
chr9_+_21746785 1.85 ENSMUST00000058777.8
angiopoietin-like 8
chrX_+_72030945 1.85 ENSMUST00000164800.8
ENSMUST00000114546.9
zinc finger protein 185
chr3_+_19698631 1.80 ENSMUST00000029139.9
tripartite motif-containing 55
chr9_+_90045109 1.80 ENSMUST00000113059.8
ENSMUST00000167122.8
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 7
chr9_-_108141105 1.79 ENSMUST00000166905.8
ENSMUST00000191899.6
dystroglycan 1
chr16_-_85347305 1.78 ENSMUST00000175700.8
ENSMUST00000114174.3
cysteine and tyrosine-rich protein 1
chr3_-_57483175 1.77 ENSMUST00000029380.14
WW domain containing transcription regulator 1
chr11_+_106265645 1.76 ENSMUST00000106816.8
proline rich 29
chr18_+_24842493 1.76 ENSMUST00000037097.9
ENSMUST00000234526.2
ENSMUST00000234834.2
formin homology 2 domain containing 3
chr8_-_11528615 1.75 ENSMUST00000033900.7
RAB20, member RAS oncogene family
chr9_+_90045219 1.75 ENSMUST00000147250.8
ENSMUST00000113060.3
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 7
chr2_+_131075965 1.75 ENSMUST00000041362.12
ENSMUST00000110199.3
mitochondrial antiviral signaling protein
chr2_-_92201311 1.71 ENSMUST00000176774.8
LARGE xylosyl- and glucuronyltransferase 2
chr15_-_101833160 1.71 ENSMUST00000023797.8
keratin 4
chr2_+_172392911 1.69 ENSMUST00000170744.2
transcription factor AP-2, gamma
chr1_-_132067343 1.68 ENSMUST00000112362.3
cyclin-dependent kinase 18
chr13_-_34529157 1.68 ENSMUST00000040336.12
solute carrier family 22, member 23
chr15_+_78912642 1.68 ENSMUST00000180086.3
H1.0 linker histone
chr11_-_69696428 1.59 ENSMUST00000051025.5
transmembrane protein 102
chr19_+_44744484 1.59 ENSMUST00000174490.9
paired box 2
chr2_+_30061469 1.59 ENSMUST00000015481.6
endonuclease G
chr9_+_37439367 1.57 ENSMUST00000002011.14
endothelial cell-specific adhesion molecule
chr10_+_108168520 1.57 ENSMUST00000218332.2
PRKC, apoptosis, WT1, regulator
chr11_+_60428788 1.56 ENSMUST00000044250.4
alkB homolog 5, RNA demethylase
chr6_-_52195663 1.55 ENSMUST00000134367.4
homeobox A7
chr7_+_45522551 1.54 ENSMUST00000211234.2
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1
chr11_+_67689094 1.53 ENSMUST00000168612.8
dehydrogenase/reductase (SDR family) member 7C
chr5_-_98178811 1.50 ENSMUST00000031281.14
anthrax toxin receptor 2
chr8_-_117720198 1.49 ENSMUST00000040484.6
glycine cleavage system protein H (aminomethyl carrier)
chr15_-_7427815 1.47 ENSMUST00000096494.5
EGF-like, fibronectin type III and laminin G domains
chr15_-_7427759 1.47 ENSMUST00000058593.10
EGF-like, fibronectin type III and laminin G domains
chr16_-_3895642 1.46 ENSMUST00000006137.9
TNF receptor-associated protein 1
chr14_+_67470735 1.44 ENSMUST00000022637.14
early B cell factor 2
chr5_-_53370761 1.44 ENSMUST00000031090.8
sel-1 suppressor of lin-12-like 3 (C. elegans)
chr17_-_85097945 1.43 ENSMUST00000112308.9
leucine-rich PPR-motif containing
chr8_-_71964379 1.43 ENSMUST00000048452.6
plasmalemma vesicle associated protein
chr7_+_127400016 1.42 ENSMUST00000106271.2
ENSMUST00000138432.2
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7
chr3_+_121220146 1.42 ENSMUST00000029773.13
calponin 3, acidic
chr3_+_145694400 1.40 ENSMUST00000200546.2
synapse defective 1, Rho GTPase, homolog 2 (C. elegans)
chr2_-_33530492 1.40 ENSMUST00000176067.2
ENSMUST00000239476.2
ENSMUST00000041730.12
LIM homeobox transcription factor 1 beta
chr12_+_111780604 1.36 ENSMUST00000021714.9
ENSMUST00000223211.2
ENSMUST00000222843.2
ENSMUST00000221375.2
zinc finger, FYVE domain containing 21
chr14_+_55798517 1.34 ENSMUST00000117701.8
DDB1 and CUL4 associated factor 11
chr4_+_43631935 1.33 ENSMUST00000030191.15
natriuretic peptide receptor 2
chr9_-_44632680 1.33 ENSMUST00000148929.2
ENSMUST00000123406.8
pleckstrin homology like domain, family B, member 1
chr11_+_95010935 1.32 ENSMUST00000092768.7
distal-less homeobox 3
chr3_+_94249445 1.32 ENSMUST00000198083.2
thioesterase superfamily member 5
chr4_-_144190326 1.31 ENSMUST00000105749.2
arylacetamide deacetylase like 3
chr11_+_98337655 1.31 ENSMUST00000019456.5
growth factor receptor bound protein 7
chr17_-_56312555 1.29 ENSMUST00000043785.8
signal transducing adaptor family member 2
chr11_+_6241606 1.29 ENSMUST00000003461.15
oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
chr14_+_55797934 1.28 ENSMUST00000121622.8
ENSMUST00000143431.2
ENSMUST00000150481.8
DDB1 and CUL4 associated factor 11
chr5_-_66309244 1.27 ENSMUST00000167950.8
RNA binding motif protein 47
chr2_-_104647041 1.25 ENSMUST00000117237.2
ENSMUST00000231375.2
glutamine and serine rich 1
chr10_-_95159410 1.25 ENSMUST00000217809.2
CASP2 and RIPK1 domain containing adaptor with death domain
chr19_+_24853039 1.24 ENSMUST00000073080.7
predicted gene 10053
chr4_+_140688514 1.24 ENSMUST00000010007.9
succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
chr1_-_182109773 1.22 ENSMUST00000133052.2
delta(4)-desaturase, sphingolipid 1
chr2_+_172392678 1.21 ENSMUST00000099058.10
transcription factor AP-2, gamma
chr6_-_92920466 1.20 ENSMUST00000113438.8
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 9
chr14_+_55798362 1.18 ENSMUST00000072530.11
ENSMUST00000128490.9
DDB1 and CUL4 associated factor 11
chr1_+_135768409 1.17 ENSMUST00000189826.7
troponin T2, cardiac
chrX_+_19925772 1.16 ENSMUST00000044138.8
carbohydrate (N-acetylglucosamino) sulfotransferase 7
chr6_-_40521911 1.15 ENSMUST00000089490.3
olfactory receptor 461
chr11_-_113600838 1.14 ENSMUST00000018871.8
cleavage and polyadenylation specific factor 4-like
chr6_+_48819523 1.13 ENSMUST00000204309.2
transmembrane protein 176A
chr9_-_108140904 1.13 ENSMUST00000194698.2
dystroglycan 1
chr10_-_128237087 1.12 ENSMUST00000042666.13
solute carrier family 39 (metal ion transporter), member 5
chr7_-_111379170 1.12 ENSMUST00000049430.15
ENSMUST00000106663.2
polypeptide N-acetylgalactosaminyltransferase 18
chr17_+_29077385 1.11 ENSMUST00000056866.8
patatin-like phospholipase domain containing 1
chr5_+_135754568 1.11 ENSMUST00000127096.2
P450 (cytochrome) oxidoreductase
chr15_-_89309998 1.11 ENSMUST00000168376.2
carnitine palmitoyltransferase 1b, muscle
chr2_-_155772110 1.11 ENSMUST00000109636.11
ENSMUST00000109631.8
ubiquinol-cytochrome c reductase complex assembly factor 1
chr11_+_102727122 1.10 ENSMUST00000021302.15
ENSMUST00000107072.2
HIG1 domain family, member 1B
chr17_-_68311073 1.10 ENSMUST00000024840.12
Rho GTPase activating protein 28
chr6_+_73225616 1.10 ENSMUST00000203632.2
succinate-CoA ligase, GDP-forming, alpha subunit
chr18_-_84969601 1.09 ENSMUST00000025547.4
translocase of inner mitochondrial membrane 21
chr9_+_106331111 1.09 ENSMUST00000185779.7
poly(rC) binding protein 4
chr9_-_50663648 1.09 ENSMUST00000217159.2
heat shock protein 2
chr11_-_72380730 1.08 ENSMUST00000045303.10
spinster homolog 2
chr5_-_66308421 1.08 ENSMUST00000200775.4
ENSMUST00000094756.11
RNA binding motif protein 47
chr17_-_28736483 1.07 ENSMUST00000114792.8
ENSMUST00000177939.8
FK506 binding protein 5
chr13_-_3854307 1.07 ENSMUST00000077698.5
calmodulin-like 3
chr11_+_115790768 1.06 ENSMUST00000152171.8
small integral membrane protein 5
chr11_+_86375441 1.05 ENSMUST00000020827.7
ring finger protein, transmembrane 1
chr1_-_136876902 1.05 ENSMUST00000195428.2
nuclear receptor subfamily 5, group A, member 2
chr16_+_48662894 1.05 ENSMUST00000238847.2
ENSMUST00000023329.7
resistin like alpha
chr9_-_45817666 1.04 ENSMUST00000161187.8
ring finger protein 214
chr7_+_139695707 1.04 ENSMUST00000211757.2
polyamine oxidase (exo-N4-amino)
chr9_+_106331041 1.04 ENSMUST00000024260.14
ENSMUST00000216379.2
ENSMUST00000215656.2
ENSMUST00000214252.2
poly(rC) binding protein 4
chr8_-_65471175 1.02 ENSMUST00000078409.5
ENSMUST00000048565.9
tripartite motif-containing 61
tripartite motif-containing 60
chr5_-_31453206 1.02 ENSMUST00000041266.11
ENSMUST00000172435.8
ENSMUST00000201417.2
fibronectin type III domain containing 4
chr3_-_92393193 1.02 ENSMUST00000054599.8
small proline-rich protein 1A
chr2_-_155771938 1.01 ENSMUST00000152766.8
ENSMUST00000139232.8
ENSMUST00000109632.8
ENSMUST00000006036.13
ENSMUST00000142655.2
ENSMUST00000159238.2
ubiquinol-cytochrome c reductase complex assembly factor 1
chr2_-_35995283 0.98 ENSMUST00000112960.8
ENSMUST00000112967.12
ENSMUST00000112963.8
LIM homeobox protein 6
chr11_+_70431063 0.98 ENSMUST00000018429.12
ENSMUST00000108557.10
ENSMUST00000108556.2
phospholipase D2
chr2_+_90865958 0.98 ENSMUST00000111445.10
ENSMUST00000111446.10
ENSMUST00000050323.6
receptor-associated protein of the synapse
chr13_-_21257469 0.97 ENSMUST00000058168.2
olfactory receptor 1370
chr7_+_45522196 0.97 ENSMUST00000002855.14
ENSMUST00000211716.2
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1
chr5_-_37874461 0.97 ENSMUST00000094836.6
serine/threonine kinase 32B
chr17_-_74354844 0.94 ENSMUST00000043458.9
steroid 5 alpha-reductase 2
chr6_-_39702381 0.94 ENSMUST00000002487.15
Braf transforming gene
chr15_+_102178975 0.93 ENSMUST00000181801.2
predicted gene 9918
chr1_+_187341225 0.92 ENSMUST00000110939.8
estrogen-related receptor gamma
chr11_+_106265660 0.91 ENSMUST00000188561.7
ENSMUST00000190795.7
ENSMUST00000185986.7
ENSMUST00000190268.2
proline rich 29
chr7_-_89166781 0.91 ENSMUST00000041761.7
protease, serine 23
chr8_+_93687561 0.90 ENSMUST00000072939.8
solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2
chr14_-_104081119 0.90 ENSMUST00000227824.2
ENSMUST00000172237.2
endothelin receptor type B
chr3_+_138058139 0.89 ENSMUST00000090166.5
alcohol dehydrogenase 6B (class V)
chr8_-_71308229 0.89 ENSMUST00000212086.2
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1
chr2_-_102903680 0.88 ENSMUST00000132449.8
ENSMUST00000111183.2
ENSMUST00000011058.9
pyruvate dehydrogenase complex, component X
chr17_-_74017410 0.88 ENSMUST00000112591.3
ENSMUST00000024858.12
polypeptide N-acetylgalactosaminyltransferase 14
chr11_+_115790951 0.88 ENSMUST00000142089.2
ENSMUST00000131566.2
small integral membrane protein 5
chr3_+_63203235 0.88 ENSMUST00000194134.6
membrane metallo endopeptidase
chr14_+_30853010 0.88 ENSMUST00000227096.2
5'-nucleotidase domain containing 2
chr15_-_85466009 0.87 ENSMUST00000023015.15
wingless-type MMTV integration site family, member 7B
chr5_+_53748323 0.86 ENSMUST00000201883.4
recombination signal binding protein for immunoglobulin kappa J region
chr2_+_121287444 0.86 ENSMUST00000126764.2
huntingtin interacting protein K
chr1_+_187340952 0.86 ENSMUST00000127489.8
estrogen-related receptor gamma
chr7_+_44117475 0.85 ENSMUST00000118493.8
Josephin domain containing 2
chr4_+_106418224 0.85 ENSMUST00000047973.4
24-dehydrocholesterol reductase
chr10_+_106306122 0.84 ENSMUST00000029404.17
ENSMUST00000217854.2
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2
chr6_-_124790029 0.84 ENSMUST00000149610.3
triosephosphate isomerase 1
chrX_+_139857640 0.84 ENSMUST00000112971.2
autophagy related 4A, cysteine peptidase
chr2_+_102904014 0.83 ENSMUST00000011055.7
APAF1 interacting protein
chr11_+_102556397 0.83 ENSMUST00000100378.4
meiosis specific with coiled-coil domain
chr7_+_43079512 0.83 ENSMUST00000004732.7
lens intrinsic membrane protein 2
chr7_-_140530194 0.83 ENSMUST00000026562.6
interferon induced transmembrane protein 5
chr16_-_59459486 0.83 ENSMUST00000149797.3
ENSMUST00000023405.16
ADP-ribosylation factor-like 6
chr7_-_49286594 0.83 ENSMUST00000032717.7
developing brain homeobox 1
chr2_+_19450443 0.82 ENSMUST00000028068.3
pancreas specific transcription factor, 1a
chr4_+_156300325 0.81 ENSMUST00000105572.3
PPARGC1 and ESRR induced regulator, muscle 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
9.5 28.5 GO:0009095 tyrosine biosynthetic process(GO:0006571) aromatic amino acid family biosynthetic process(GO:0009073) aromatic amino acid family biosynthetic process, prephenate pathway(GO:0009095)
1.9 5.8 GO:0019264 glycine biosynthetic process from serine(GO:0019264)
1.9 5.6 GO:0006212 uracil catabolic process(GO:0006212) uracil metabolic process(GO:0019860)
1.2 13.6 GO:0035754 B cell chemotaxis(GO:0035754)
1.0 7.0 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
1.0 2.9 GO:0021682 nerve maturation(GO:0021682)
0.7 5.8 GO:0003072 regulation of blood vessel size by renin-angiotensin(GO:0002034) renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure(GO:0003072)
0.7 2.9 GO:0060598 dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis(GO:0060598)
0.7 4.3 GO:1902512 positive regulation of apoptotic DNA fragmentation(GO:1902512)
0.6 2.4 GO:0007161 calcium-independent cell-matrix adhesion(GO:0007161)
0.6 1.7 GO:1900063 regulation of peroxisome organization(GO:1900063)
0.6 3.9 GO:0003383 apical constriction(GO:0003383)
0.6 2.8 GO:0071475 cellular hyperosmotic salinity response(GO:0071475)
0.5 1.6 GO:0035566 optic nerve formation(GO:0021634) regulation of metanephros size(GO:0035566) optic chiasma development(GO:0061360) regulation of optic nerve formation(GO:2000595) positive regulation of optic nerve formation(GO:2000597)
0.5 3.7 GO:0072257 metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
0.5 1.6 GO:0060450 positive regulation of amyloid precursor protein biosynthetic process(GO:0042986) positive regulation of hindgut contraction(GO:0060450) regulation of relaxation of smooth muscle(GO:1901080) positive regulation of relaxation of smooth muscle(GO:1901082)
0.5 3.0 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.5 1.5 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.5 1.5 GO:1901856 negative regulation of cellular respiration(GO:1901856)
0.4 1.3 GO:0035965 cardiolipin acyl-chain remodeling(GO:0035965)
0.4 2.1 GO:1902163 negative regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902163)
0.4 2.0 GO:0006538 glutamate catabolic process(GO:0006538)
0.4 1.9 GO:0005984 disaccharide metabolic process(GO:0005984)
0.4 2.5 GO:0006621 protein retention in ER lumen(GO:0006621)
0.4 1.4 GO:0000960 mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
0.3 1.4 GO:0002930 trabecular meshwork development(GO:0002930)
0.3 1.0 GO:0046203 spermidine catabolic process(GO:0046203)
0.3 3.7 GO:0007525 somatic muscle development(GO:0007525)
0.3 1.3 GO:0071895 odontoblast differentiation(GO:0071895)
0.3 1.8 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.3 0.8 GO:0019405 alditol catabolic process(GO:0019405) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.3 1.1 GO:0043602 nitrate catabolic process(GO:0043602) nitric oxide catabolic process(GO:0046210) cellular organohalogen metabolic process(GO:0090345) cellular organofluorine metabolic process(GO:0090346)
0.3 1.1 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.3 1.6 GO:0035553 oxidative single-stranded RNA demethylation(GO:0035553)
0.3 1.8 GO:0090383 phagosome acidification(GO:0090383)
0.2 1.0 GO:0032972 regulation of muscle filament sliding speed(GO:0032972)
0.2 2.9 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.2 1.2 GO:1905068 positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.2 2.4 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
0.2 3.9 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.2 1.1 GO:0034224 cellular response to zinc ion starvation(GO:0034224)
0.2 1.6 GO:0051697 protein delipidation(GO:0051697)
0.2 1.8 GO:1904378 maintenance of unfolded protein(GO:0036506) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
0.2 2.9 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.2 0.9 GO:0016332 establishment or maintenance of polarity of embryonic epithelium(GO:0016332)
0.2 2.4 GO:0007021 tubulin complex assembly(GO:0007021)
0.2 4.6 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.2 0.8 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.2 2.7 GO:0016554 cytidine to uridine editing(GO:0016554)
0.2 2.7 GO:0070131 positive regulation of mitochondrial translation(GO:0070131)
0.2 0.6 GO:0071550 death-inducing signaling complex assembly(GO:0071550)
0.2 3.6 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977)
0.2 2.0 GO:0035360 positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360)
0.2 1.4 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.2 3.3 GO:0033280 response to vitamin D(GO:0033280)
0.2 0.5 GO:1903778 protein localization to vacuolar membrane(GO:1903778)
0.2 0.7 GO:0043418 homocysteine catabolic process(GO:0043418)
0.2 0.9 GO:0046449 creatinine metabolic process(GO:0046449) cellular lactam metabolic process(GO:0072338)
0.2 2.1 GO:0098719 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.2 3.0 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.2 0.5 GO:1903412 response to bile acid(GO:1903412) cellular response to bile acid(GO:1903413)
0.2 0.8 GO:1903445 intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445)
0.2 1.6 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.2 2.5 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.2 0.5 GO:0072076 nephrogenic mesenchyme development(GO:0072076)
0.1 0.9 GO:0014826 vein smooth muscle contraction(GO:0014826)
0.1 0.4 GO:1902167 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902167)
0.1 1.7 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.1 0.4 GO:0043181 vacuolar sequestering(GO:0043181)
0.1 1.1 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376)
0.1 1.3 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.1 1.6 GO:0006105 succinate metabolic process(GO:0006105)
0.1 1.2 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.1 0.2 GO:0046881 positive regulation of follicle-stimulating hormone secretion(GO:0046881)
0.1 1.0 GO:0021853 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.1 3.5 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)
0.1 0.6 GO:0021775 smoothened signaling pathway involved in ventral spinal cord interneuron specification(GO:0021775) smoothened signaling pathway involved in spinal cord motor neuron cell fate specification(GO:0021776)
0.1 1.2 GO:0010764 negative regulation of fibroblast migration(GO:0010764)
0.1 3.2 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.1 0.3 GO:0050883 negative regulation of sodium:proton antiporter activity(GO:0032416) musculoskeletal movement, spinal reflex action(GO:0050883)
0.1 1.3 GO:1904259 regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
0.1 1.5 GO:0010820 positive regulation of T cell chemotaxis(GO:0010820)
0.1 0.3 GO:1903401 mitochondrial ornithine transport(GO:0000066) L-lysine transport(GO:1902022) L-ornithine transmembrane transport(GO:1903352) L-arginine transmembrane transport(GO:1903400) L-lysine transmembrane transport(GO:1903401) arginine transmembrane transport(GO:1903826)
0.1 0.4 GO:1904046 negative regulation of vascular endothelial growth factor production(GO:1904046)
0.1 0.5 GO:0046668 regulation of retinal cell programmed cell death(GO:0046668)
0.1 1.4 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.1 3.3 GO:0060644 mammary gland epithelial cell differentiation(GO:0060644)
0.1 2.5 GO:0001573 ganglioside metabolic process(GO:0001573)
0.1 0.7 GO:0072602 interleukin-4 secretion(GO:0072602)
0.1 10.1 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.1 1.1 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.1 0.3 GO:0097402 neuroblast migration(GO:0097402)
0.1 0.8 GO:0061074 regulation of neural retina development(GO:0061074)
0.1 0.3 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
0.1 0.3 GO:0032877 positive regulation of DNA endoreduplication(GO:0032877)
0.1 3.9 GO:0060065 uterus development(GO:0060065)
0.1 0.4 GO:0061534 gamma-aminobutyric acid secretion, neurotransmission(GO:0061534)
0.1 0.6 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.1 0.9 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.1 1.5 GO:0045656 negative regulation of monocyte differentiation(GO:0045656)
0.1 0.6 GO:1900109 regulation of histone H3-K9 dimethylation(GO:1900109)
0.1 1.1 GO:0061113 pancreas morphogenesis(GO:0061113)
0.1 1.1 GO:2001199 negative regulation of dendritic cell differentiation(GO:2001199)
0.1 0.2 GO:0045627 positive regulation of T-helper 1 cell differentiation(GO:0045627)
0.1 0.8 GO:0007144 female meiosis I(GO:0007144)
0.1 0.7 GO:1901029 negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
0.1 0.4 GO:2000360 negative regulation of binding of sperm to zona pellucida(GO:2000360)
0.1 3.8 GO:0051353 positive regulation of oxidoreductase activity(GO:0051353)
0.1 1.4 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.1 2.8 GO:0061036 positive regulation of cartilage development(GO:0061036)
0.1 0.7 GO:0036309 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.1 0.9 GO:0061370 testosterone biosynthetic process(GO:0061370)
0.1 3.1 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.1 3.4 GO:0042092 type 2 immune response(GO:0042092)
0.1 2.2 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.1 1.0 GO:0071340 skeletal muscle acetylcholine-gated channel clustering(GO:0071340)
0.1 1.9 GO:0036342 post-anal tail morphogenesis(GO:0036342)
0.1 1.1 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617)
0.1 2.8 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.1 0.8 GO:0060573 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.1 0.4 GO:0035262 gonad morphogenesis(GO:0035262)
0.1 0.2 GO:0055099 response to high density lipoprotein particle(GO:0055099)
0.1 0.4 GO:0061525 hindgut development(GO:0061525)
0.1 1.4 GO:0002693 positive regulation of cellular extravasation(GO:0002693)
0.1 0.2 GO:0036228 protein targeting to nuclear inner membrane(GO:0036228)
0.1 2.0 GO:0006767 water-soluble vitamin metabolic process(GO:0006767)
0.1 1.0 GO:0002031 G-protein coupled receptor internalization(GO:0002031)
0.1 9.4 GO:0007050 cell cycle arrest(GO:0007050)
0.1 0.7 GO:0071361 cellular response to ethanol(GO:0071361)
0.1 0.3 GO:1902340 telomeric heterochromatin assembly(GO:0031509) negative regulation of chromosome condensation(GO:1902340)
0.1 1.3 GO:0034063 stress granule assembly(GO:0034063)
0.1 1.4 GO:0035563 positive regulation of chromatin binding(GO:0035563)
0.1 0.3 GO:0010796 regulation of multivesicular body size(GO:0010796)
0.1 1.6 GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
0.1 0.4 GO:1903011 negative regulation of bone development(GO:1903011) negative regulation of osteoclast development(GO:2001205)
0.0 1.5 GO:0010880 regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum(GO:0010880)
0.0 0.5 GO:0070814 homoserine metabolic process(GO:0009092) transsulfuration(GO:0019346) hydrogen sulfide biosynthetic process(GO:0070814)
0.0 0.1 GO:0014908 myotube differentiation involved in skeletal muscle regeneration(GO:0014908)
0.0 0.5 GO:0044829 positive regulation by host of viral genome replication(GO:0044829)
0.0 0.3 GO:1901314 negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315)
0.0 3.0 GO:0015909 long-chain fatty acid transport(GO:0015909)
0.0 1.2 GO:0044458 motile cilium assembly(GO:0044458)
0.0 0.2 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.0 0.9 GO:0015874 norepinephrine transport(GO:0015874)
0.0 0.6 GO:2000643 positive regulation of early endosome to late endosome transport(GO:2000643)
0.0 0.8 GO:0006656 phosphatidylcholine biosynthetic process(GO:0006656)
0.0 0.2 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.0 0.8 GO:0030539 male genitalia development(GO:0030539)
0.0 1.1 GO:0019433 triglyceride catabolic process(GO:0019433)
0.0 1.8 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 0.4 GO:0006013 mannose metabolic process(GO:0006013)
0.0 0.3 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.0 0.2 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.0 0.2 GO:0033326 cerebrospinal fluid secretion(GO:0033326)
0.0 1.0 GO:0031424 keratinization(GO:0031424)
0.0 0.6 GO:0048485 sympathetic nervous system development(GO:0048485)
0.0 0.2 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.0 0.5 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.0 1.5 GO:1901998 toxin transport(GO:1901998)
0.0 0.3 GO:0099515 actin filament-based transport(GO:0099515)
0.0 0.4 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.0 0.8 GO:0045669 positive regulation of osteoblast differentiation(GO:0045669)
0.0 0.1 GO:0051122 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.0 1.7 GO:0006334 nucleosome assembly(GO:0006334)
0.0 0.5 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.4 GO:0030157 pancreatic juice secretion(GO:0030157)
0.0 0.8 GO:0043171 peptide catabolic process(GO:0043171)
0.0 0.2 GO:0098914 membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
0.0 2.2 GO:0048704 embryonic skeletal system morphogenesis(GO:0048704)
0.0 0.2 GO:0045723 positive regulation of fatty acid biosynthetic process(GO:0045723)
0.0 0.1 GO:0042631 cellular response to water deprivation(GO:0042631) cellular response to water stimulus(GO:0071462)
0.0 0.5 GO:0010800 positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.0 1.0 GO:0030500 regulation of bone mineralization(GO:0030500)
0.0 2.6 GO:0030308 negative regulation of cell growth(GO:0030308)
0.0 1.4 GO:0050680 negative regulation of epithelial cell proliferation(GO:0050680)
0.0 0.6 GO:0010257 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.3 GO:0035428 hexose transmembrane transport(GO:0035428)
0.0 0.4 GO:0051290 protein heterotetramerization(GO:0051290)
0.0 0.3 GO:0006744 ubiquinone biosynthetic process(GO:0006744)
0.0 0.8 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.0 0.2 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.0 3.2 GO:0006631 fatty acid metabolic process(GO:0006631)
0.0 0.2 GO:0045060 negative thymic T cell selection(GO:0045060)
0.0 0.1 GO:1901897 regulation of relaxation of cardiac muscle(GO:1901897)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 5.8 GO:0005577 fibrinogen complex(GO:0005577)
0.6 5.8 GO:0070552 BRISC complex(GO:0070552)
0.5 1.5 GO:0014801 longitudinal sarcoplasmic reticulum(GO:0014801)
0.5 3.9 GO:0033269 internode region of axon(GO:0033269)
0.5 2.0 GO:0034686 integrin alphav-beta8 complex(GO:0034686)
0.3 6.1 GO:0097512 cardiac myofibril(GO:0097512)
0.3 1.2 GO:0045273 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.3 2.7 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.2 2.9 GO:0016011 dystroglycan complex(GO:0016011)
0.2 1.8 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.2 1.2 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.1 0.6 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559)
0.1 0.4 GO:0060473 cortical granule(GO:0060473)
0.1 1.3 GO:0045240 dihydrolipoyl dehydrogenase complex(GO:0045240) oxoglutarate dehydrogenase complex(GO:0045252)
0.1 0.7 GO:0071817 MMXD complex(GO:0071817)
0.1 1.1 GO:0030062 mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.1 1.1 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.1 0.9 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.1 2.9 GO:0005614 interstitial matrix(GO:0005614)
0.1 2.0 GO:0046581 intercellular canaliculus(GO:0046581)
0.1 3.8 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.1 0.4 GO:0097598 sperm cytoplasmic droplet(GO:0097598)
0.1 1.3 GO:0045180 basal cortex(GO:0045180)
0.1 2.9 GO:0045095 keratin filament(GO:0045095)
0.1 2.0 GO:0000786 nucleosome(GO:0000786)
0.1 0.7 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.1 1.1 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.1 0.9 GO:0070852 cell body fiber(GO:0070852)
0.1 1.3 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.2 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.0 0.4 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.0 1.6 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.3 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.6 GO:0016589 NURF complex(GO:0016589)
0.0 9.5 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 1.0 GO:0099634 postsynaptic specialization membrane(GO:0099634)
0.0 1.9 GO:0005865 striated muscle thin filament(GO:0005865)
0.0 2.4 GO:0005801 cis-Golgi network(GO:0005801)
0.0 4.6 GO:0005604 basement membrane(GO:0005604)
0.0 0.4 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.5 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.6 GO:0030008 TRAPP complex(GO:0030008)
0.0 5.3 GO:0005884 actin filament(GO:0005884)
0.0 1.4 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.5 GO:0042599 lamellar body(GO:0042599)
0.0 0.2 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 4.9 GO:0005903 brush border(GO:0005903)
0.0 2.1 GO:1990204 oxidoreductase complex(GO:1990204)
0.0 0.5 GO:0005771 multivesicular body(GO:0005771)
0.0 0.7 GO:0031430 M band(GO:0031430)
0.0 0.5 GO:0000421 autophagosome membrane(GO:0000421)
0.0 1.5 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 1.0 GO:0001533 cornified envelope(GO:0001533)
0.0 0.4 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 5.3 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 4.5 GO:0005765 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 0.2 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.0 0.2 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.9 GO:0045335 phagocytic vesicle(GO:0045335)
0.0 2.8 GO:0005923 bicellular tight junction(GO:0005923)
0.0 5.3 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 1.1 GO:0005811 lipid particle(GO:0005811)
0.0 0.6 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 7.3 GO:0005667 transcription factor complex(GO:0005667)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
4.7 28.5 GO:0004505 phenylalanine 4-monooxygenase activity(GO:0004505)
3.4 13.6 GO:0047016 cholest-5-ene-3-beta,7-alpha-diol 3-beta-dehydrogenase activity(GO:0047016)
1.9 5.8 GO:0004372 glycine hydroxymethyltransferase activity(GO:0004372)
1.9 5.6 GO:0002061 uracil binding(GO:0002058) pyrimidine nucleobase binding(GO:0002061)
0.8 10.1 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.7 2.8 GO:0035827 rubidium ion transmembrane transporter activity(GO:0035827)
0.7 8.3 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.6 3.8 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.6 3.0 GO:0004923 leukemia inhibitory factor receptor activity(GO:0004923)
0.5 2.1 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.5 2.0 GO:0008160 protein tyrosine phosphatase activator activity(GO:0008160)
0.5 2.5 GO:0046923 ER retention sequence binding(GO:0046923)
0.5 3.0 GO:0016416 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.4 1.2 GO:0051538 succinate dehydrogenase (ubiquinone) activity(GO:0008177) 3 iron, 4 sulfur cluster binding(GO:0051538)
0.4 1.1 GO:0004774 succinate-CoA ligase activity(GO:0004774)
0.4 2.9 GO:0043237 laminin-1 binding(GO:0043237)
0.3 1.2 GO:0042284 sphingolipid delta-4 desaturase activity(GO:0042284)
0.3 0.9 GO:0005333 norepinephrine transmembrane transporter activity(GO:0005333)
0.3 0.9 GO:0004962 endothelin receptor activity(GO:0004962)
0.3 1.1 GO:0016708 nitric oxide dioxygenase activity(GO:0008941) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor(GO:0016708) iron-cytochrome-c reductase activity(GO:0047726)
0.3 1.6 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
0.2 1.0 GO:0030172 troponin C binding(GO:0030172)
0.2 0.9 GO:0047751 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) cholestenone 5-alpha-reductase activity(GO:0047751)
0.2 0.7 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.2 1.3 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.2 0.9 GO:1902379 chemoattractant activity involved in axon guidance(GO:1902379)
0.2 3.4 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.2 4.8 GO:0016805 dipeptidase activity(GO:0016805)
0.2 1.0 GO:0052901 polyamine oxidase activity(GO:0046592) spermine:oxygen oxidoreductase (spermidine-forming) activity(GO:0052901)
0.2 2.1 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.2 1.7 GO:0042285 xylosyltransferase activity(GO:0042285)
0.2 1.1 GO:0030280 structural constituent of epidermis(GO:0030280)
0.2 1.1 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.2 1.2 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.2 0.5 GO:0016784 3-mercaptopyruvate sulfurtransferase activity(GO:0016784)
0.2 1.9 GO:0050700 CARD domain binding(GO:0050700)
0.2 0.6 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.1 0.6 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
0.1 0.9 GO:0034604 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.1 0.4 GO:0070002 glutamic-type peptidase activity(GO:0070002)
0.1 2.9 GO:0005523 tropomyosin binding(GO:0005523)
0.1 2.5 GO:0070513 death domain binding(GO:0070513)
0.1 3.0 GO:0017081 chloride channel regulator activity(GO:0017081)
0.1 1.2 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.1 1.6 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.1 3.6 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 0.3 GO:0005292 high-affinity basic amino acid transmembrane transporter activity(GO:0005287) high-affinity arginine transmembrane transporter activity(GO:0005289) high-affinity lysine transmembrane transporter activity(GO:0005292)
0.1 0.4 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.1 0.6 GO:0089720 death effector domain binding(GO:0035877) caspase binding(GO:0089720)
0.1 1.9 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.1 1.6 GO:0043522 leucine zipper domain binding(GO:0043522)
0.1 1.8 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.1 0.8 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.1 13.8 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 0.7 GO:0001849 complement component C1q binding(GO:0001849)
0.1 1.5 GO:0015643 toxic substance binding(GO:0015643)
0.1 3.5 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.1 0.5 GO:0071532 ankyrin repeat binding(GO:0071532)
0.1 1.3 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.1 0.4 GO:0005223 intracellular cAMP activated cation channel activity(GO:0005222) intracellular cGMP activated cation channel activity(GO:0005223)
0.1 0.7 GO:0005347 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.1 1.5 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.1 0.6 GO:0008046 axon guidance receptor activity(GO:0008046)
0.1 3.4 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.1 1.7 GO:0003680 AT DNA binding(GO:0003680)
0.1 0.2 GO:0034188 apolipoprotein receptor activity(GO:0030226) apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.1 1.4 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.1 0.3 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.1 0.4 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.1 0.7 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.1 3.4 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.1 1.0 GO:0043495 protein anchor(GO:0043495)
0.1 1.2 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 0.4 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.1 1.1 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1 0.5 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.1 1.1 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.3 GO:0032027 myosin light chain binding(GO:0032027)
0.0 1.4 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.0 0.4 GO:0008429 phosphatidylethanolamine binding(GO:0008429) syndecan binding(GO:0045545)
0.0 1.2 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.0 5.4 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.0 0.2 GO:0070815 peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.0 2.1 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 0.8 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.8 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.0 0.5 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.4 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.2 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.2 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.0 1.1 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 2.4 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 0.4 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 3.1 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.2 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.2 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.0 3.3 GO:0005179 hormone activity(GO:0005179)
0.0 1.9 GO:0051287 NAD binding(GO:0051287)
0.0 0.1 GO:0004052 arachidonate 12-lipoxygenase activity(GO:0004052)
0.0 1.9 GO:0015179 L-amino acid transmembrane transporter activity(GO:0015179)
0.0 0.4 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0 0.5 GO:0042171 lysophosphatidic acid acyltransferase activity(GO:0042171)
0.0 3.2 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 0.9 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 1.2 GO:0008237 metallopeptidase activity(GO:0008237)
0.0 1.1 GO:0004521 endoribonuclease activity(GO:0004521)
0.0 0.5 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 1.1 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 0.1 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.0 0.7 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.0 1.1 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.1 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.0 2.1 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds(GO:0004553)
0.0 1.6 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.2 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 1.5 GO:0051082 unfolded protein binding(GO:0051082)
0.0 1.5 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors(GO:0016614)
0.0 0.8 GO:0005504 fatty acid binding(GO:0005504)
0.0 0.7 GO:0016836 hydro-lyase activity(GO:0016836)
0.0 0.2 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.2 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.1 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 16.5 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.1 4.0 PID ARF 3PATHWAY Arf1 pathway
0.1 3.3 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.1 2.0 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 1.2 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.1 1.5 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.1 2.8 PID ALK1 PATHWAY ALK1 signaling events
0.1 4.8 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 2.9 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.1 14.3 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 3.4 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 3.9 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 3.0 PID ENDOTHELIN PATHWAY Endothelins
0.0 4.6 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 1.3 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.3 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.0 0.7 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 1.3 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 1.2 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.3 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.7 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 1.9 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 1.1 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 0.5 PID NOTCH PATHWAY Notch signaling pathway
0.0 0.5 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 13.6 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.5 1.9 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.3 5.6 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.3 9.1 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.2 1.7 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.1 3.9 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1 3.6 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.1 4.6 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.1 1.7 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.1 2.7 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 3.7 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.1 3.1 REACTOME PYRUVATE METABOLISM AND CITRIC ACID TCA CYCLE Genes involved in Pyruvate metabolism and Citric Acid (TCA) cycle
0.1 4.2 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.1 28.7 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.1 3.0 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.1 1.2 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.1 1.2 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.1 1.3 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 3.3 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 1.1 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.9 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 1.9 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 4.9 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.4 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.2 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 4.6 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 1.8 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.8 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.3 REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0 0.7 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.2 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.3 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 1.0 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 5.3 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 2.0 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 1.9 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.8 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.2 REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES Genes involved in p75NTR recruits signalling complexes
0.0 0.3 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.7 REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS Genes involved in Interactions of Vpr with host cellular proteins
0.0 0.5 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.3 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.2 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.4 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
0.0 0.4 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.7 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction