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PRJNA375882: Comprehensive Mouse Transcriptomic BodyMap

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Results for Zkscan3

Z-value: 0.68

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Transcription factors associated with Zkscan3

Gene Symbol Gene ID Gene Info
Zkscan3
ENSMUSG00000021327.20 Zkscan3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Zkscan3mm39_v1_chr13_-_21586858_215869250.019.4e-01Click!

Activity profile of Zkscan3 motif

Sorted Z-values of Zkscan3 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of Zkscan3

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr5_-_100720063 7.12 ENSMUST00000031264.12
Plac8
placenta-specific 8
chr2_+_118603247 6.72 ENSMUST00000061360.4
ENSMUST00000130293.8
Phgr1
proline/histidine/glycine-rich 1
chr1_+_160806241 4.99 ENSMUST00000195760.2
Serpinc1
serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1
chr17_-_34694911 4.93 ENSMUST00000065841.5
Btnl4
butyrophilin-like 4
chr11_+_115802828 4.65 ENSMUST00000132961.2
Smim6
small integral membrane protein 6
chr6_+_71176811 4.56 ENSMUST00000067492.8
Fabp1
fatty acid binding protein 1, liver
chr17_-_34736326 4.09 ENSMUST00000075483.5
Btnl6
butyrophilin-like 6
chr2_-_30084124 3.69 ENSMUST00000113659.8
ENSMUST00000113660.2
Kyat1
kynurenine aminotransferase 1
chr1_+_160806194 3.31 ENSMUST00000064725.11
ENSMUST00000191936.2
Serpinc1
serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1
chr9_+_53212871 3.26 ENSMUST00000051014.2
Exph5
exophilin 5
chr16_+_32555015 3.22 ENSMUST00000239554.1
Muc4
mucin 4
chr2_+_154042291 3.10 ENSMUST00000028987.7
Bpifb1
BPI fold containing family B, member 1
chr6_+_125048230 2.93 ENSMUST00000140346.9
ENSMUST00000171989.3
Lpar5
lysophosphatidic acid receptor 5
chr6_-_113696809 2.89 ENSMUST00000203770.3
ENSMUST00000064993.8
Ghrl
ghrelin
chr7_+_3339059 2.81 ENSMUST00000096744.8
Myadm
myeloid-associated differentiation marker
chr1_+_58834621 2.80 ENSMUST00000191201.7
Casp8
caspase 8
chr6_-_43643093 2.78 ENSMUST00000114644.8
ENSMUST00000067888.14
Tpk1
thiamine pyrophosphokinase
chr7_+_3339077 2.72 ENSMUST00000203566.3
Myadm
myeloid-associated differentiation marker
chr1_+_58834532 2.66 ENSMUST00000027189.15
Casp8
caspase 8
chr19_+_10611574 2.58 ENSMUST00000055115.9
Vwce
von Willebrand factor C and EGF domains
chr1_+_180770016 2.29 ENSMUST00000027800.15
Tmem63a
transmembrane protein 63a
chr6_+_149041289 2.18 ENSMUST00000126406.8
Etfbkmt
electron transfer flavoprotein beta subunit lysine methyltransferase
chr1_+_180770064 2.15 ENSMUST00000159436.8
Tmem63a
transmembrane protein 63a
chr2_+_103926140 2.10 ENSMUST00000168176.8
ENSMUST00000040423.12
Cd59a
CD59a antigen
chr8_-_112417633 2.09 ENSMUST00000034435.7
Ctrb1
chymotrypsinogen B1
chr3_-_129518723 1.96 ENSMUST00000199615.5
ENSMUST00000197079.5
Egf
epidermal growth factor
chr6_-_142418801 1.90 ENSMUST00000032371.8
Gys2
glycogen synthase 2
chr16_+_17149235 1.80 ENSMUST00000023450.15
ENSMUST00000231884.2
Serpind1
serine (or cysteine) peptidase inhibitor, clade D, member 1
chr11_+_35660288 1.78 ENSMUST00000018990.8
Pank3
pantothenate kinase 3
chr3_+_146205864 1.77 ENSMUST00000119130.2
Gng5
guanine nucleotide binding protein (G protein), gamma 5
chr11_-_75313350 1.77 ENSMUST00000125982.2
ENSMUST00000137103.8
Serpinf1
serine (or cysteine) peptidase inhibitor, clade F, member 1
chr4_+_144340236 1.72 ENSMUST00000094510.4
Aadacl4
arylacetamide deacetylase like 4
chr16_-_56891711 1.71 ENSMUST00000067173.8
ENSMUST00000227043.2
Tmem45a2
transmembrane protein 45A2
chr7_-_97827461 1.66 ENSMUST00000040971.14
Capn5
calpain 5
chr11_-_75313412 1.61 ENSMUST00000138661.8
ENSMUST00000000769.14
Serpinf1
serine (or cysteine) peptidase inhibitor, clade F, member 1
chr10_+_75404482 1.59 ENSMUST00000134503.8
ENSMUST00000125770.8
ENSMUST00000128886.8
ENSMUST00000151212.8
Ggt1
gamma-glutamyltransferase 1
chr10_+_75404464 1.50 ENSMUST00000145928.8
ENSMUST00000131565.8
Ggt1
gamma-glutamyltransferase 1
chr6_-_97436223 1.43 ENSMUST00000113359.8
Frmd4b
FERM domain containing 4B
chr12_+_33004178 1.41 ENSMUST00000020885.13
Sypl
synaptophysin-like protein
chr3_-_95595157 1.35 ENSMUST00000015994.4
ENSMUST00000148854.2
ENSMUST00000117782.8
Adamtsl4
ADAMTS-like 4
chr6_-_122833109 1.34 ENSMUST00000042081.9
C3ar1
complement component 3a receptor 1
chr7_+_126358785 1.34 ENSMUST00000205657.2
Mapk3
mitogen-activated protein kinase 3
chr6_+_116327853 1.29 ENSMUST00000140884.8
ENSMUST00000129170.8
Marchf8
membrane associated ring-CH-type finger 8
chr13_-_104246084 1.25 ENSMUST00000224945.2
ENSMUST00000109315.5
Nln
neurolysin (metallopeptidase M3 family)
chrX_-_74918122 1.25 ENSMUST00000033547.14
Pls3
plastin 3 (T-isoform)
chr15_-_4008913 1.14 ENSMUST00000022791.9
Fbxo4
F-box protein 4
chr13_-_65260716 1.13 ENSMUST00000054730.10
ENSMUST00000155487.8
Mfsd14b
major facilitator superfamily domain containing 14B
chr7_+_126358771 1.12 ENSMUST00000050201.11
ENSMUST00000057669.16
Mapk3
mitogen-activated protein kinase 3
chr13_-_64514830 1.11 ENSMUST00000222971.2
Ctsl
cathepsin L
chr1_-_128256048 1.08 ENSMUST00000073490.7
Lct
lactase
chr8_-_71213535 1.04 ENSMUST00000038626.10
Mpv17l2
MPV17 mitochondrial membrane protein-like 2
chr19_+_6952580 1.01 ENSMUST00000237084.2
ENSMUST00000236218.2
ENSMUST00000237235.2
Ppp1r14b
protein phosphatase 1, regulatory inhibitor subunit 14B
chr11_-_33528933 1.00 ENSMUST00000020366.8
ENSMUST00000135350.2
Gabrp
gamma-aminobutyric acid (GABA) A receptor, pi
chr1_-_84262274 1.00 ENSMUST00000177458.2
ENSMUST00000168574.9
Pid1
phosphotyrosine interaction domain containing 1
chr1_-_40829801 0.95 ENSMUST00000039672.6
Mfsd9
major facilitator superfamily domain containing 9
chr7_-_80994933 0.95 ENSMUST00000080813.5
Rps17
ribosomal protein S17
chr4_-_62438122 0.91 ENSMUST00000107444.8
ENSMUST00000030090.4
Alad
aminolevulinate, delta-, dehydratase
chr7_-_141936355 0.89 ENSMUST00000133843.8
Gm49369
predicted gene, 49369
chrX_-_17438470 0.88 ENSMUST00000176638.8
Fundc1
FUN14 domain containing 1
chr8_+_84262409 0.84 ENSMUST00000214156.2
ENSMUST00000209408.4
Olfr370
olfactory receptor 370
chr2_+_32536594 0.80 ENSMUST00000113272.8
ENSMUST00000009705.14
ENSMUST00000167841.8
Eng
endoglin
chr2_-_121001577 0.76 ENSMUST00000163766.8
ENSMUST00000146243.2
Zscan29
zinc finger SCAN domains 29
chr10_+_81164552 0.74 ENSMUST00000105325.4
ENSMUST00000220312.2
Tbxa2r
thromboxane A2 receptor
chrX_+_162923474 0.65 ENSMUST00000073973.11
Ace2
angiotensin I converting enzyme (peptidyl-dipeptidase A) 2
chr6_-_135145129 0.63 ENSMUST00000045855.9
Hebp1
heme binding protein 1
chr11_-_102109748 0.60 ENSMUST00000131254.2
Hdac5
histone deacetylase 5
chr5_-_88823472 0.59 ENSMUST00000113234.8
ENSMUST00000153565.8
Grsf1
G-rich RNA sequence binding factor 1
chr8_-_13250535 0.58 ENSMUST00000165605.4
ENSMUST00000209691.2
ENSMUST00000211128.2
ENSMUST00000210317.2
Grtp1
GH regulated TBC protein 1
chr8_-_107620147 0.57 ENSMUST00000176090.2
Chtf8
CTF8, chromosome transmission fidelity factor 8
chr4_+_15957923 0.56 ENSMUST00000029879.15
ENSMUST00000149069.2
Nbn
nibrin
chr5_+_114141894 0.54 ENSMUST00000086599.11
Dao
D-amino acid oxidase
chr14_+_54413230 0.53 ENSMUST00000103700.2
Traj42
T cell receptor alpha joining 42
chr12_-_112640378 0.47 ENSMUST00000130342.2
Akt1
thymoma viral proto-oncogene 1
chr5_-_136003294 0.44 ENSMUST00000154181.2
ENSMUST00000111152.8
ENSMUST00000111153.8
Ssc4d
scavenger receptor cysteine rich family, 4 domains
chr5_+_24791796 0.41 ENSMUST00000197318.2
Chpf2
chondroitin polymerizing factor 2
chr1_-_185061525 0.37 ENSMUST00000027921.11
ENSMUST00000110975.8
ENSMUST00000110974.4
Iars2
isoleucine-tRNA synthetase 2, mitochondrial
chr2_+_31560725 0.36 ENSMUST00000038474.14
ENSMUST00000137156.2
Exosc2
exosome component 2
chr3_+_87458556 0.35 ENSMUST00000238853.2
Etv3l
ets variant 3-like
chr14_+_54412058 0.32 ENSMUST00000103699.2
Traj43
T cell receptor alpha joining 43
chrX_-_17437801 0.31 ENSMUST00000177213.8
Fundc1
FUN14 domain containing 1
chr14_+_54413727 0.30 ENSMUST00000103701.2
Traj41
T cell receptor alpha joining 41
chr2_-_103609703 0.29 ENSMUST00000143188.2
Caprin1
cell cycle associated protein 1
chr14_-_62718581 0.28 ENSMUST00000186010.8
Gm4131
predicted gene 4131
chr15_-_37004302 0.26 ENSMUST00000228275.2
Zfp706
zinc finger protein 706
chr4_-_155947819 0.24 ENSMUST00000030949.4
Tas1r3
taste receptor, type 1, member 3
chr1_+_38037086 0.24 ENSMUST00000027252.8
Eif5b
eukaryotic translation initiation factor 5B
chr3_-_97318495 0.23 ENSMUST00000060912.4
Olfr1402
olfactory receptor 1402
chr8_+_95537074 0.22 ENSMUST00000034232.3
Ccl17
chemokine (C-C motif) ligand 17
chr11_-_88742285 0.22 ENSMUST00000107903.8
Akap1
A kinase (PRKA) anchor protein 1
chrX_-_17438520 0.20 ENSMUST00000026016.13
Fundc1
FUN14 domain containing 1
chr6_-_43286488 0.19 ENSMUST00000031749.16
Nobox
NOBOX oogenesis homeobox
chr13_-_19579961 0.16 ENSMUST00000039694.13
Stard3nl
STARD3 N-terminal like
chr9_+_114517812 0.14 ENSMUST00000047404.7
Dync1li1
dynein cytoplasmic 1 light intermediate chain 1
chr8_-_107620210 0.12 ENSMUST00000177068.8
ENSMUST00000176515.2
ENSMUST00000169312.2
Chtf8
Derpc
CTF8, chromosome transmission fidelity factor 8
DERPC proline and glycine rich nuclear protein
chr3_-_63836796 0.09 ENSMUST00000061706.7
E130311K13Rik
RIKEN cDNA E130311K13 gene
chr5_+_53424471 0.09 ENSMUST00000147148.5
Smim20
small integral membrane protein 20
chr13_-_19579898 0.07 ENSMUST00000197565.3
ENSMUST00000221380.2
ENSMUST00000200323.3
ENSMUST00000199924.2
ENSMUST00000222869.2
Stard3nl
STARD3 N-terminal like
chr17_-_35984409 0.05 ENSMUST00000162266.8
ENSMUST00000160734.8
ENSMUST00000159852.2
ENSMUST00000160039.8
Gtf2h4
general transcription factor II H, polypeptide 4

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.7 GO:0097052 L-kynurenine metabolic process(GO:0097052)
1.0 8.3 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.7 2.2 GO:1904736 negative regulation of electron carrier activity(GO:1904733) regulation of fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:1904735) negative regulation of fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:1904736)
0.7 2.9 GO:2000506 regulation of gastric mucosal blood circulation(GO:1904344) positive regulation of gastric mucosal blood circulation(GO:1904346) gastric mucosal blood circulation(GO:1990768) negative regulation of energy homeostasis(GO:2000506)
0.7 2.8 GO:0006772 thiamine metabolic process(GO:0006772) thiamine-containing compound metabolic process(GO:0042723)
0.7 5.5 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.7 4.1 GO:0045062 extrathymic T cell selection(GO:0045062)
0.6 3.2 GO:0002835 negative regulation of response to tumor cell(GO:0002835) negative regulation of immune response to tumor cell(GO:0002838)
0.6 2.5 GO:2000657 regulation of apolipoprotein binding(GO:2000656) negative regulation of apolipoprotein binding(GO:2000657)
0.5 3.3 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.4 5.5 GO:0036462 TRAIL-activated apoptotic signaling pathway(GO:0036462)
0.4 3.1 GO:0031179 peptide modification(GO:0031179) leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.3 4.6 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.3 3.4 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.3 1.6 GO:0001905 activation of membrane attack complex(GO:0001905) regulation of activation of membrane attack complex(GO:0001969)
0.3 1.3 GO:0002461 tolerance induction dependent upon immune response(GO:0002461)
0.3 0.8 GO:0003032 detection of oxygen(GO:0003032) cardiac jelly development(GO:1905072)
0.3 3.1 GO:0034144 negative regulation of toll-like receptor 4 signaling pathway(GO:0034144)
0.2 2.0 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.2 1.1 GO:0010040 response to iron(II) ion(GO:0010040)
0.2 1.0 GO:2001274 positive regulation of fat cell proliferation(GO:0070346) negative regulation of ATP biosynthetic process(GO:2001170) negative regulation of glucose import in response to insulin stimulus(GO:2001274)
0.2 1.8 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.2 7.1 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.2 0.5 GO:0055130 D-serine catabolic process(GO:0036088) D-alanine family amino acid metabolic process(GO:0046144) D-alanine metabolic process(GO:0046436) D-alanine catabolic process(GO:0055130)
0.2 1.3 GO:1902809 regulation of skeletal muscle fiber differentiation(GO:1902809)
0.2 1.0 GO:0061668 mitochondrial ribosome assembly(GO:0061668)
0.2 0.7 GO:0015827 aromatic amino acid transport(GO:0015801) tryptophan transport(GO:0015827)
0.1 2.9 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.1 0.6 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.1 1.1 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.1 0.4 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
0.1 0.5 GO:0060709 glycogen cell differentiation involved in embryonic placenta development(GO:0060709)
0.1 1.8 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.1 0.4 GO:0071043 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.1 1.1 GO:0042637 catagen(GO:0042637)
0.1 0.7 GO:1900264 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.0 1.2 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.2 GO:0050917 sensory perception of sweet taste(GO:0050916) sensory perception of umami taste(GO:0050917)
0.0 0.6 GO:0048742 regulation of skeletal muscle fiber development(GO:0048742)
0.0 0.9 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 1.5 GO:0042168 heme metabolic process(GO:0042168)
0.0 0.2 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
0.0 1.4 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 1.9 GO:0009250 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0 0.3 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
0.0 0.7 GO:1900048 positive regulation of blood coagulation(GO:0030194) positive regulation of hemostasis(GO:1900048)
0.0 0.1 GO:0090267 positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267)
0.0 0.2 GO:0006968 cellular defense response(GO:0006968)
0.0 1.6 GO:0007586 digestion(GO:0007586)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 5.5 GO:0030690 Noc1p-Noc2p complex(GO:0030690)
0.4 1.8 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.4 4.6 GO:0045179 apical cortex(GO:0045179)
0.2 3.4 GO:0043203 axon hillock(GO:0043203)
0.1 2.5 GO:0031143 pseudopodium(GO:0031143)
0.1 3.2 GO:0031528 microvillus membrane(GO:0031528)
0.1 0.6 GO:0030870 Mre11 complex(GO:0030870)
0.1 0.7 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.1 7.4 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.1 0.6 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.1 1.4 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 1.4 GO:0005614 interstitial matrix(GO:0005614)
0.0 1.4 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 1.0 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 0.9 GO:0005839 proteasome core complex(GO:0005839)
0.0 0.4 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 6.9 GO:0072562 blood microparticle(GO:0072562)
0.0 6.6 GO:0005765 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 1.2 GO:0032420 stereocilium(GO:0032420)
0.0 1.0 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.2 GO:0030061 mitochondrial crista(GO:0030061)
0.0 1.3 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 1.1 GO:0005902 microvillus(GO:0005902)
0.0 1.1 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.6 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 5.5 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
1.2 3.7 GO:0047316 L-phenylalanine:pyruvate aminotransferase activity(GO:0047312) glutamine-phenylpyruvate transaminase activity(GO:0047316) L-glutamine:pyruvate aminotransferase activity(GO:0047945)
1.0 2.9 GO:0031768 ghrelin receptor binding(GO:0031768)
0.6 1.9 GO:0004373 glycogen (starch) synthase activity(GO:0004373)
0.6 2.8 GO:0016778 diphosphotransferase activity(GO:0016778)
0.5 4.6 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.3 1.8 GO:0004594 pantothenate kinase activity(GO:0004594)
0.3 3.1 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.3 1.3 GO:0070012 oligopeptidase activity(GO:0070012)
0.2 3.2 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.2 1.1 GO:0030984 kininogen binding(GO:0030984)
0.2 1.1 GO:0008422 beta-glucosidase activity(GO:0008422)
0.1 1.3 GO:0004875 complement receptor activity(GO:0004875)
0.1 0.5 GO:0003884 D-amino-acid oxidase activity(GO:0003884)
0.1 0.4 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
0.1 0.7 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.1 2.5 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.1 0.8 GO:0005534 galactose binding(GO:0005534)
0.1 0.6 GO:0001226 RNA polymerase II transcription corepressor binding(GO:0001226)
0.1 2.0 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 13.5 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 1.6 GO:0001848 complement binding(GO:0001848)
0.1 0.7 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.1 1.7 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.7 GO:0004954 prostanoid receptor activity(GO:0004954)
0.0 1.0 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 2.2 GO:0016279 lysine N-methyltransferase activity(GO:0016278) protein-lysine N-methyltransferase activity(GO:0016279)
0.0 0.5 GO:0030235 nitric-oxide synthase regulator activity(GO:0030235)
0.0 0.2 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.0 0.1 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 3.1 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 0.5 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.9 GO:0016836 hydro-lyase activity(GO:0016836)
0.0 1.8 GO:0030165 PDZ domain binding(GO:0030165)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 5.5 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.2 8.3 PID GLYPICAN 1PATHWAY Glypican 1 network
0.1 2.5 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.1 2.0 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 7.3 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.8 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.5 PID S1P S1P3 PATHWAY S1P3 pathway
0.0 3.2 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.6 PID ATM PATHWAY ATM pathway
0.0 0.7 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.0 1.0 PID ILK PATHWAY Integrin-linked kinase signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 8.3 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.3 5.5 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.3 1.1 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.2 2.5 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.1 2.9 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.1 1.8 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.1 2.0 REACTOME SHC1 EVENTS IN EGFR SIGNALING Genes involved in SHC1 events in EGFR signaling
0.1 0.7 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.1 1.9 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 3.1 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.1 1.7 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 2.8 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 1.8 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 0.8 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0 0.9 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.6 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 4.6 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 1.1 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 1.9 REACTOME GLUCOSE METABOLISM Genes involved in Glucose metabolism
0.0 0.4 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.9 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 2.2 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.2 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)