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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for BX548005.1+smarcc2

Z-value: 2.72

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Transcription factors associated with BX548005.1+smarcc2

Gene Symbol Gene ID Gene Info
smarcc2
ENSDARG00000077946 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2
BX548005.1
ENSDARG00000110907 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
smarcc2dr11_v1_chr6_+_39836474_39836474-0.427.9e-02Click!

Activity profile of BX548005.1+smarcc2 motif

Sorted Z-values of BX548005.1+smarcc2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr11_+_29537756 12.28 ENSDART00000103388
wu:fi42e03
wu:fi42e03
chr23_+_13528550 11.30 ENSDART00000099903
uckl1b
uridine-cytidine kinase 1-like 1b
chr11_-_16021424 9.14 ENSDART00000193291
ENSDART00000170731
ENSDART00000104107
zgc:173544
zgc:173544
chr7_+_41887429 7.76 ENSDART00000115090
gpt2
glutamic pyruvate transaminase (alanine aminotransferase) 2
chr5_-_43859148 7.42 ENSDART00000162746
ENSDART00000128763
si:ch211-204c21.1
si:ch211-204c21.1
chr5_+_3891485 7.34 ENSDART00000129329
ENSDART00000091711
rpain
RPA interacting protein
chr16_-_34285106 7.19 ENSDART00000044235
phactr4b
phosphatase and actin regulator 4b
chr8_-_36618073 6.83 ENSDART00000047912
gpkow
G patch domain and KOW motifs
chr6_+_59176470 6.78 ENSDART00000161720
shmt2
serine hydroxymethyltransferase 2 (mitochondrial)
chr5_-_23675222 6.66 ENSDART00000135153
TBC1D8B
si:dkey-110k5.6
chr12_-_13730501 6.29 ENSDART00000152370
foxh1
forkhead box H1
chr3_-_26184018 6.14 ENSDART00000191604
si:ch211-11k18.4
si:ch211-11k18.4
chr20_+_14789305 6.08 ENSDART00000002463
tmed5
transmembrane p24 trafficking protein 5
chr24_-_9989634 5.84 ENSDART00000115275
zgc:152652
zgc:152652
chr20_-_28842524 5.81 ENSDART00000046035
ENSDART00000139843
ENSDART00000129858
ENSDART00000137425
ENSDART00000135720
max
myc associated factor X
chr20_+_14789148 5.79 ENSDART00000164761
tmed5
transmembrane p24 trafficking protein 5
chr24_-_5932982 5.70 ENSDART00000138412
ENSDART00000135124
ENSDART00000007373
acbd5a
acyl-CoA binding domain containing 5a
chr8_+_26410197 5.58 ENSDART00000145836
ENSDART00000053447
ifrd2
interferon-related developmental regulator 2
chr17_-_16324565 5.35 ENSDART00000030835
hmbox1a
homeobox containing 1a
chr2_-_57110477 5.33 ENSDART00000181132
slc25a42
solute carrier family 25, member 42
chr3_-_26183699 5.16 ENSDART00000147517
ENSDART00000140731
si:ch211-11k18.4
si:ch211-11k18.4
chr23_-_4019928 5.13 ENSDART00000021062
slc9a8
solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
chr23_-_4019699 5.04 ENSDART00000159780
slc9a8
solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
chr22_+_25088999 5.00 ENSDART00000158225
rrbp1b
ribosome binding protein 1b
chr15_-_25435085 4.93 ENSDART00000112079
tlcd2
TLC domain containing 2
chr13_-_15929402 4.92 ENSDART00000090273
ttl
tubulin tyrosine ligase
chr15_-_31147301 4.91 ENSDART00000157145
ENSDART00000155473
ENSDART00000048103
ksr1b
kinase suppressor of ras 1b
chr11_+_37638873 4.84 ENSDART00000186384
ENSDART00000184291
ENSDART00000131782
ENSDART00000140502
sh2d5
SH2 domain containing 5
chr5_-_10082244 4.75 ENSDART00000036421
chek2
checkpoint kinase 2
chr18_+_46162204 4.73 ENSDART00000113545
ENSDART00000147556
zgc:113340
zgc:113340
chr3_+_27664864 4.72 ENSDART00000126533
ENSDART00000180848
clcn7
chloride channel 7
chr16_-_39267185 4.71 ENSDART00000058550
ENSDART00000133642
gpd1l
glycerol-3-phosphate dehydrogenase 1 like
chr17_+_53186347 4.68 ENSDART00000155981
dph6
diphthamine biosynthesis 6
chr8_+_26410539 4.62 ENSDART00000168780
ifrd2
interferon-related developmental regulator 2
chr3_+_27665160 4.60 ENSDART00000103660
clcn7
chloride channel 7
chr3_+_24060454 4.57 ENSDART00000143088
cbx1a
chromobox homolog 1a (HP1 beta homolog Drosophila)
chr13_-_33654931 4.56 ENSDART00000020350
snx5
sorting nexin 5
chr15_+_2857556 4.56 ENSDART00000157758
mre11a
MRE11 homolog A, double strand break repair nuclease
chr14_-_12106603 4.55 ENSDART00000054619
prps1b
phosphoribosyl pyrophosphate synthetase 1B
chr6_-_39700965 4.48 ENSDART00000156645
espl1
extra spindle pole bodies like 1, separase
chr13_-_31389661 4.45 ENSDART00000134630
zdhhc16a
zinc finger, DHHC-type containing 16a
chr23_-_26227805 4.41 ENSDART00000158082
BX927204.1

chr15_-_2857961 4.34 ENSDART00000033263
ankrd49
ankyrin repeat domain 49
chr8_+_12951155 4.33 ENSDART00000081601
cept1a
choline/ethanolamine phosphotransferase 1a
chr13_+_2861265 4.29 ENSDART00000170602
ENSDART00000171687
XPO5
si:ch211-233m11.2
chr16_+_23495600 4.24 ENSDART00000021092
snx27b
sorting nexin family member 27b
chr18_-_16953978 4.18 ENSDART00000100126
akip1
A kinase (PRKA) interacting protein 1
chr23_-_26228077 4.18 ENSDART00000162423
BX927204.1

chr18_+_21951551 4.16 ENSDART00000146261
ranbp10
RAN binding protein 10
chr4_+_25912308 4.15 ENSDART00000167845
ENSDART00000136927
vezt
vezatin, adherens junctions transmembrane protein
chr11_-_35171768 4.09 ENSDART00000192896
traip
TRAF-interacting protein
chr8_-_18613948 4.09 ENSDART00000089172
cpox
coproporphyrinogen oxidase
chr23_+_33947874 4.06 ENSDART00000136104
si:ch211-148l7.4
si:ch211-148l7.4
chr24_-_23716097 4.05 ENSDART00000084954
ENSDART00000129028
pign
phosphatidylinositol glycan anchor biosynthesis, class N
chr4_+_25912654 4.02 ENSDART00000109508
ENSDART00000134218
vezt
vezatin, adherens junctions transmembrane protein
chr16_-_2390931 3.98 ENSDART00000149463
hace1
HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1
chr21_+_8427059 3.95 ENSDART00000143151
dennd1a
DENN/MADD domain containing 1A
chr11_-_35171162 3.92 ENSDART00000017393
traip
TRAF-interacting protein
chr17_+_25187670 3.85 ENSDART00000190873
cln8
CLN8, transmembrane ER and ERGIC protein
chr8_-_16725959 3.84 ENSDART00000183593
depdc1a
DEP domain containing 1a
chr5_+_37379825 3.80 ENSDART00000171826
klhl13
kelch-like family member 13
chr9_+_37754845 3.72 ENSDART00000100592
pdia5
protein disulfide isomerase family A, member 5
chr7_+_33372680 3.69 ENSDART00000193436
ENSDART00000099988
glceb
glucuronic acid epimerase b
chr16_-_55259199 3.68 ENSDART00000161130
iqgap3
IQ motif containing GTPase activating protein 3
chr13_+_32454262 3.62 ENSDART00000057421
rdh14a
retinol dehydrogenase 14a
chr11_-_18283886 3.61 ENSDART00000019248
stimate
STIM activating enhance
chr18_-_27316599 3.61 ENSDART00000028294
zgc:56106
zgc:56106
chr1_+_9153141 3.60 ENSDART00000081343
plk1
polo-like kinase 1 (Drosophila)
chr23_+_13528053 3.58 ENSDART00000162217
uckl1b
uridine-cytidine kinase 1-like 1b
chr20_-_3997531 3.54 ENSDART00000092217
ttc13
tetratricopeptide repeat domain 13
chr3_+_35608385 3.53 ENSDART00000193219
ENSDART00000132703
traf7
TNF receptor-associated factor 7
chr1_+_49878000 3.51 ENSDART00000047876
lef1
lymphoid enhancer-binding factor 1
chr4_-_14954327 3.50 ENSDART00000182729
slc26a5
solute carrier family 26 (anion exchanger), member 5
chr12_+_8474868 3.44 ENSDART00000062858
adoa
2-aminoethanethiol (cysteamine) dioxygenase a
chr15_-_37589600 3.43 ENSDART00000154641
proser3
proline and serine rich 3
chr8_+_48942470 3.41 ENSDART00000005464
ENSDART00000132035
rer1
retention in endoplasmic reticulum sorting receptor 1
chr7_-_55633475 3.41 ENSDART00000149478
galns
galactosamine (N-acetyl)-6-sulfatase
chr15_+_25528290 3.41 ENSDART00000123143
npat
nuclear protein, ataxia-telangiectasia locus
chr18_+_49969568 3.40 ENSDART00000126916
mob2b
MOB kinase activator 2b
chr19_-_12648122 3.38 ENSDART00000151184
fam210aa
family with sequence similarity 210, member Aa
chr14_-_26411918 3.37 ENSDART00000020582
tmed9
transmembrane p24 trafficking protein 9
chr15_-_44052927 3.33 ENSDART00000166209
wu:fb44b02
wu:fb44b02
chr6_+_8652310 3.32 ENSDART00000105098
usp40
ubiquitin specific peptidase 40
chr16_-_41535690 3.28 ENSDART00000102662
rpp25l
ribonuclease P/MRP 25 subunit-like
chr8_+_26396552 3.28 ENSDART00000087151
amt
aminomethyltransferase
chr9_-_34945566 3.27 ENSDART00000131908
ENSDART00000059861
dcun1d2a
DCN1, defective in cullin neddylation 1, domain containing 2a
chr14_+_989733 3.26 ENSDART00000161487
ENSDART00000127317
si:ch73-308l14.2
si:ch73-308l14.2
chr12_-_314899 3.25 ENSDART00000066579
pts
6-pyruvoyltetrahydropterin synthase
chr20_+_3997684 3.24 ENSDART00000113184
arv1
ARV1 homolog, fatty acid homeostasis modulator
chr10_+_38663917 3.20 ENSDART00000170182
acat1
acetyl-CoA acetyltransferase 1
chr8_+_40275830 3.19 ENSDART00000164414
orai1a
ORAI calcium release-activated calcium modulator 1a
chr17_+_26803470 3.18 ENSDART00000023470
pgrmc2
progesterone receptor membrane component 2
chr2_+_36608387 3.16 ENSDART00000159541
pak2a
p21 protein (Cdc42/Rac)-activated kinase 2a
chr5_-_26795438 3.14 ENSDART00000146124
si:ch211-102c2.7
si:ch211-102c2.7
chr13_+_39315881 3.14 ENSDART00000135999
si:dkey-85a20.4
si:dkey-85a20.4
chr2_+_31942390 3.09 ENSDART00000138684
ENSDART00000146758
ENSDART00000137921
otulinb
OTU deubiquitinase with linear linkage specificity b
chr19_-_432083 3.08 ENSDART00000165371
dus3l
dihydrouridine synthase 3-like (S. cerevisiae)
chr13_+_28785814 3.08 ENSDART00000039028
nsmce4a
NSE4 homolog A, SMC5-SMC6 complex component
chr23_+_36306539 3.07 ENSDART00000053267
hnrnpa1b
heterogeneous nuclear ribonucleoprotein A1b
chr24_+_37709191 3.04 ENSDART00000066558
decr2
2,4-dienoyl CoA reductase 2, peroxisomal
chr24_-_36301072 3.01 ENSDART00000062736
coasy
CoA synthase
chr22_+_22302614 2.99 ENSDART00000049434
scamp4
secretory carrier membrane protein 4
chr19_-_23227582 2.97 ENSDART00000042172
grb10a
growth factor receptor-bound protein 10a
chr3_+_866044 2.96 ENSDART00000126857
FP102786.1

chr16_-_39195318 2.96 ENSDART00000058546
ebag9
estrogen receptor binding site associated, antigen, 9
chr11_-_44999858 2.94 ENSDART00000167759
ENSDART00000126845
ldb1b
LIM-domain binding 1b
chr22_-_506522 2.93 ENSDART00000106645
ENSDART00000067637
dstyk
dual serine/threonine and tyrosine protein kinase
chr10_+_37182626 2.90 ENSDART00000137636
ksr1a
kinase suppressor of ras 1a
chr19_-_12648408 2.88 ENSDART00000103692
fam210aa
family with sequence similarity 210, member Aa
chr19_+_26072624 2.87 ENSDART00000147627
jarid2b
jumonji, AT rich interactive domain 2b
chr25_-_3347418 2.85 ENSDART00000082385
golt1bb
golgi transport 1Bb
chr20_+_9474841 2.84 ENSDART00000053847
rad51b
RAD51 paralog B
chr11_+_34921492 2.81 ENSDART00000128070
gnai2a
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2a
chr23_+_43870886 2.76 ENSDART00000102658
ENSDART00000149088
nfxl1
nuclear transcription factor, X-box binding-like 1
chr8_+_16726386 2.75 ENSDART00000144621
smim15
small integral membrane protein 15
chr4_-_14954029 2.71 ENSDART00000038642
slc26a5
solute carrier family 26 (anion exchanger), member 5
chr7_-_36358303 2.70 ENSDART00000130028
fto
fat mass and obesity associated
chr6_-_3998199 2.69 ENSDART00000059212
unc50
unc-50 homolog (C. elegans)
chr6_+_36821621 2.67 ENSDART00000104157
tmem45a
transmembrane protein 45a
chr10_+_44699734 2.66 ENSDART00000167952
ENSDART00000158681
ENSDART00000190188
ENSDART00000168276
scarb1
scavenger receptor class B, member 1
chr21_+_13327527 2.66 ENSDART00000114294
snrpd3l
small nuclear ribonucleoprotein D3 polypeptide, like
chr17_-_8692722 2.65 ENSDART00000148931
ENSDART00000192891
ctbp2a
C-terminal binding protein 2a
chr16_-_30655980 2.61 ENSDART00000146508
ldlrad4b
low density lipoprotein receptor class A domain containing 4b
chr12_+_36109071 2.58 ENSDART00000171268
map2k6
mitogen-activated protein kinase kinase 6
chr7_+_32897723 2.57 ENSDART00000146789
ENSDART00000140775
ENSDART00000142049
ENSDART00000145523
ENSDART00000135237
ENSDART00000133584
ENSDART00000140800
ENSDART00000137956
ENSDART00000075263
tssc4
tumor suppressing subtransferable candidate 4
chr23_+_43668756 2.55 ENSDART00000112598
otud4
OTU deubiquitinase 4
chr13_-_33054847 2.55 ENSDART00000057379
ENSDART00000135955
vti1b
vesicle transport through interaction with t-SNAREs 1B
chr17_-_12764360 2.53 ENSDART00000003418
brms1la
breast cancer metastasis-suppressor 1-like a
chr9_-_3519717 2.52 ENSDART00000145043
dcaf17
ddb1 and cul4 associated factor 17
chr7_+_7696665 2.50 ENSDART00000091099
ino80b
INO80 complex subunit B
chr10_+_36037977 2.49 ENSDART00000164678
katnal1
katanin p60 subunit A-like 1
chr2_-_22659450 2.49 ENSDART00000115025
thap4
THAP domain containing 4
chr16_+_38240027 2.48 ENSDART00000111081
prune
prune exopolyphosphatase
chr8_-_39984593 2.46 ENSDART00000140127
asphd2
aspartate beta-hydroxylase domain containing 2
chr15_-_6966221 2.41 ENSDART00000165487
ENSDART00000027657
mrps22
mitochondrial ribosomal protein S22
chr7_+_29863548 2.39 ENSDART00000136555
ENSDART00000134068
tln2a
talin 2a
chr25_-_25646806 2.39 ENSDART00000089066
tbc1d2b
TBC1 domain family, member 2B
chr15_-_34878388 2.38 ENSDART00000154094
mgat1a
mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase a
chr6_-_58975010 2.38 ENSDART00000144911
ENSDART00000144514
mars
methionyl-tRNA synthetase
chr3_+_31058464 2.38 ENSDART00000153381
si:dkey-66i24.7
si:dkey-66i24.7
chr8_+_48943009 2.37 ENSDART00000180763
rer1
retention in endoplasmic reticulum sorting receptor 1
chr1_-_59243542 2.37 ENSDART00000163021
mvb12a
multivesicular body subunit 12A
chr5_+_15495351 2.37 ENSDART00000111646
ENSDART00000114446
suds3
SDS3 homolog, SIN3A corepressor complex component
chr19_-_3726768 2.36 ENSDART00000161738
smim13
small integral membrane protein 13
chr2_+_5841108 2.33 ENSDART00000136180
dis3l2
DIS3 like 3'-5' exoribonuclease 2
chr16_+_30604387 2.31 ENSDART00000058785
fam210ab
family with sequence similarity 210, member Ab
chr16_-_32662947 2.31 ENSDART00000034109
coq3
coenzyme Q3 methyltransferase
chr8_+_52284075 2.31 ENSDART00000098439
ube2d4
ubiquitin-conjugating enzyme E2D 4 (putative)
chr19_-_46058963 2.30 ENSDART00000170409
nup153
nucleoporin 153
chr21_-_11054605 2.30 ENSDART00000191378
ENSDART00000084061
nedd4l
neural precursor cell expressed, developmentally down-regulated 4-like
chr18_-_38244871 2.30 ENSDART00000076399
nat10
N-acetyltransferase 10
chr3_+_36646054 2.29 ENSDART00000170013
ENSDART00000159948
gspt1l
G1 to S phase transition 1, like
chr3_+_26905024 2.29 ENSDART00000077835
dexi
Dexi homolog (mouse)
chr21_+_43485512 2.28 ENSDART00000026666
atg4a
autophagy related 4A, cysteine peptidase
chr7_-_17712665 2.28 ENSDART00000149047
men1
multiple endocrine neoplasia I
chr8_-_31384607 2.26 ENSDART00000164134
ENSDART00000024872
creb3l3l
cAMP responsive element binding protein 3-like 3 like
chr21_+_3854414 2.24 ENSDART00000122699
miga2
mitoguardin 2
chr25_-_31763897 2.23 ENSDART00000041740
ubl7a
ubiquitin-like 7a (bone marrow stromal cell-derived)
chr5_-_67349916 2.21 ENSDART00000144092
mlxip
MLX interacting protein
chr10_+_36441124 2.21 ENSDART00000185626
uspl1
ubiquitin specific peptidase like 1
chr9_-_23242684 2.20 ENSDART00000053282
ENSDART00000179770
ccnt2a
cyclin T2a
chr14_+_30795559 2.18 ENSDART00000006132
cfl1
cofilin 1
chr14_-_30876708 2.17 ENSDART00000147597
ubl3b
ubiquitin-like 3b
chr5_+_8196264 2.16 ENSDART00000174564
ENSDART00000161261
lmbrd2a
LMBR1 domain containing 2a
chr14_+_30775066 2.16 ENSDART00000139975
ENSDART00000144921
atl3
atlastin 3
chr24_-_25788841 2.15 ENSDART00000132235
klhl24b
kelch-like family member 24b
chr3_-_31115601 2.15 ENSDART00000139090
arl6ip1
ADP-ribosylation factor-like 6 interacting protein 1
chr24_-_38131381 2.13 ENSDART00000105666
crp6
C-reactive protein 6
chr10_+_44700103 2.13 ENSDART00000165999
scarb1
scavenger receptor class B, member 1
chr16_+_25137483 2.10 ENSDART00000155666
znf576.1
zinc finger protein 576, tandem duplicate 1
chr14_+_30774515 2.07 ENSDART00000191666
atl3
atlastin 3
chr25_+_15273370 2.05 ENSDART00000045659
tcp11l1
t-complex 11, testis-specific-like 1
chr23_-_36305874 2.02 ENSDART00000147598
ENSDART00000146986
ENSDART00000086985
ENSDART00000133259
cbx5
chromobox homolog 5 (HP1 alpha homolog, Drosophila)
chr24_+_29352039 2.02 ENSDART00000101641
prmt6
protein arginine methyltransferase 6
chr5_+_61361815 2.01 ENSDART00000009507
gatsl2
GATS protein-like 2
chr16_-_34401412 2.01 ENSDART00000054020
hivep3b
human immunodeficiency virus type I enhancer binding protein 3b
chr23_+_20640484 2.01 ENSDART00000054691
uba1
ubiquitin-like modifier activating enzyme 1
chr2_+_31308587 2.01 ENSDART00000027090
clul1
clusterin-like 1 (retinal)
chr23_-_36306337 2.00 ENSDART00000142760
ENSDART00000136929
ENSDART00000143340
cbx5
chromobox homolog 5 (HP1 alpha homolog, Drosophila)
chr21_+_170038 1.98 ENSDART00000157614
klhl8
kelch-like family member 8
chr3_+_29179329 1.97 ENSDART00000085216
ENSDART00000190136
cacna1i
calcium channel, voltage-dependent, T type, alpha 1I subunit
chr1_+_35494837 1.97 ENSDART00000140724
gab1
GRB2-associated binding protein 1
chr18_-_38245062 1.96 ENSDART00000189092
nat10
N-acetyltransferase 10
chr14_+_41409697 1.95 ENSDART00000173335
bcorl1
BCL6 corepressor-like 1
chr20_-_4049862 1.93 ENSDART00000158057
sprtn
SprT-like N-terminal domain
chr14_-_30876299 1.92 ENSDART00000180305
ubl3b
ubiquitin-like 3b
chr16_-_27161410 1.91 ENSDART00000177503
LO017771.1

chr8_+_19624589 1.85 ENSDART00000185698
slc35a3a
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3a
chr1_+_24557414 1.85 ENSDART00000076519
dctpp1
dCTP pyrophosphatase 1
chr4_+_15605844 1.84 ENSDART00000101619
ENSDART00000021384
exoc4
exocyst complex component 4
chr19_+_9232676 1.84 ENSDART00000136957
kmt2ba
lysine (K)-specific methyltransferase 2Ba
chr21_-_11054876 1.83 ENSDART00000146576
nedd4l
neural precursor cell expressed, developmentally down-regulated 4-like
chr3_+_62140077 1.82 ENSDART00000108945
GID4
GID complex subunit 4 homolog
chr21_-_30284404 1.79 ENSDART00000066363
zgc:175066
zgc:175066
chr9_+_21146862 1.77 ENSDART00000136365
hao2
hydroxyacid oxidase 2 (long chain)
chr20_-_31743817 1.77 ENSDART00000137679
sash1a
SAM and SH3 domain containing 1a
chr13_-_26799244 1.73 ENSDART00000036419
vrk2
vaccinia related kinase 2
chr23_-_12158685 1.72 ENSDART00000135035
fam217b
family with sequence similarity 217, member B
chr16_+_25107344 1.71 ENSDART00000033211
zgc:66448
zgc:66448
chr22_+_8012532 1.71 ENSDART00000159439
CABZ01034698.1

Network of associatons between targets according to the STRING database.

First level regulatory network of BX548005.1+smarcc2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 6.8 GO:0019264 glycine biosynthetic process from serine(GO:0019264)
2.1 6.3 GO:0060063 Spemann organizer formation at the embryonic shield(GO:0060063)
1.7 13.4 GO:0044211 CTP salvage(GO:0044211)
1.6 4.8 GO:0043654 recognition of apoptotic cell(GO:0043654)
1.6 6.2 GO:0019532 oxalate transport(GO:0019532)
1.3 4.0 GO:2000378 negative regulation of reactive oxygen species metabolic process(GO:2000378)
1.3 4.0 GO:0042245 RNA repair(GO:0042245)
1.2 4.9 GO:0055091 phospholipid homeostasis(GO:0055091)
1.2 4.7 GO:0046168 NADH oxidation(GO:0006116) glycerol-3-phosphate catabolic process(GO:0046168)
1.1 4.5 GO:0046391 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
1.1 3.4 GO:0035964 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
1.0 7.2 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
1.0 2.9 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
1.0 5.7 GO:0030242 pexophagy(GO:0030242)
0.8 5.8 GO:0006621 protein retention in ER lumen(GO:0006621)
0.8 3.3 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.8 2.4 GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510)
0.8 4.7 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.7 4.5 GO:0021877 forebrain neuron fate commitment(GO:0021877)
0.7 2.2 GO:0030043 actin filament fragmentation(GO:0030043)
0.7 3.5 GO:0060784 regulation of cell proliferation involved in tissue homeostasis(GO:0060784)
0.6 2.6 GO:2000660 regulation of interleukin-1-mediated signaling pathway(GO:2000659) negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.6 1.9 GO:0009211 pyrimidine deoxyribonucleoside triphosphate metabolic process(GO:0009211)
0.6 4.6 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.5 3.1 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.5 3.6 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.5 4.1 GO:2000650 negative regulation of sodium ion transmembrane transporter activity(GO:2000650)
0.5 3.1 GO:1990108 protein linear deubiquitination(GO:1990108)
0.5 2.0 GO:0034969 histone arginine methylation(GO:0034969)
0.5 2.3 GO:0010586 miRNA metabolic process(GO:0010586)
0.5 2.8 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.5 3.2 GO:0032366 intracellular sterol transport(GO:0032366)
0.5 2.3 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.5 3.2 GO:0030728 ovulation(GO:0030728)
0.4 2.2 GO:0030575 nuclear body organization(GO:0030575) Cajal body organization(GO:0030576) protein localization to nuclear body(GO:1903405) protein localization to Cajal body(GO:1904867) protein localization to nucleoplasm(GO:1990173)
0.4 7.4 GO:0045807 positive regulation of endocytosis(GO:0045807)
0.4 2.7 GO:0070073 clustering of voltage-gated calcium channels(GO:0070073)
0.4 3.4 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.4 2.6 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.4 1.5 GO:0030220 platelet formation(GO:0030220) platelet morphogenesis(GO:0036344)
0.4 4.3 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.3 1.0 GO:0048682 axon extension involved in regeneration(GO:0048677) sprouting of injured axon(GO:0048682)
0.3 2.9 GO:0060036 notochord cell vacuolation(GO:0060036)
0.3 3.3 GO:0046146 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.3 4.7 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.3 2.8 GO:0035588 adenosine receptor signaling pathway(GO:0001973) purinergic receptor signaling pathway(GO:0035587) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.3 2.5 GO:0051013 microtubule severing(GO:0051013)
0.3 3.7 GO:0030202 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.3 2.7 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.3 1.2 GO:0006499 N-terminal protein myristoylation(GO:0006499) N-terminal peptidyl-glycine N-myristoylation(GO:0018008) protein myristoylation(GO:0018377)
0.3 1.5 GO:0035434 copper ion transmembrane transport(GO:0035434)
0.3 3.2 GO:0002115 store-operated calcium entry(GO:0002115)
0.3 4.3 GO:1901222 regulation of NIK/NF-kappaB signaling(GO:1901222)
0.3 2.5 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.3 1.1 GO:0002090 regulation of receptor internalization(GO:0002090)
0.3 1.1 GO:0042148 strand invasion(GO:0042148)
0.3 4.1 GO:0046501 protoporphyrinogen IX biosynthetic process(GO:0006782) protoporphyrinogen IX metabolic process(GO:0046501)
0.3 3.3 GO:0034244 negative regulation of DNA-templated transcription, elongation(GO:0032785) negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.3 1.0 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.3 1.5 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.2 1.2 GO:0019370 leukotriene metabolic process(GO:0006691) leukotriene biosynthetic process(GO:0019370)
0.2 1.8 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.2 0.9 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.2 2.5 GO:0006798 polyphosphate metabolic process(GO:0006797) polyphosphate catabolic process(GO:0006798)
0.2 3.0 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.2 3.0 GO:0046627 negative regulation of insulin receptor signaling pathway(GO:0046627) negative regulation of cellular response to insulin stimulus(GO:1900077)
0.2 3.0 GO:0045116 protein neddylation(GO:0045116) positive regulation of ubiquitin-protein transferase activity(GO:0051443)
0.2 1.4 GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.2 5.8 GO:0048264 determination of ventral identity(GO:0048264)
0.2 3.6 GO:0006613 cotranslational protein targeting to membrane(GO:0006613)
0.2 4.3 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.2 4.2 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.2 0.9 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.2 4.1 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.2 4.5 GO:0051307 meiotic chromosome separation(GO:0051307)
0.2 0.3 GO:0006296 nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296)
0.2 4.4 GO:0044773 mitotic DNA damage checkpoint(GO:0044773)
0.2 0.6 GO:0016267 O-glycan processing, core 1(GO:0016267)
0.2 0.8 GO:0036371 protein localization to T-tubule(GO:0036371)
0.1 1.3 GO:1901096 regulation of autophagosome maturation(GO:1901096)
0.1 8.4 GO:0051453 regulation of intracellular pH(GO:0051453)
0.1 1.8 GO:0006903 vesicle targeting(GO:0006903)
0.1 4.3 GO:0000154 rRNA modification(GO:0000154)
0.1 1.5 GO:0035677 posterior lateral line neuromast hair cell development(GO:0035677)
0.1 0.5 GO:0006272 leading strand elongation(GO:0006272)
0.1 0.9 GO:0061511 centriole elongation(GO:0061511)
0.1 1.9 GO:0090481 pyrimidine nucleotide-sugar transport(GO:0015781) pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.1 2.3 GO:1901663 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.1 1.7 GO:0008053 mitochondrial fusion(GO:0008053)
0.1 0.7 GO:0097010 eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.1 4.3 GO:0032456 endocytic recycling(GO:0032456)
0.1 7.2 GO:1902593 protein import into nucleus(GO:0006606) protein targeting to nucleus(GO:0044744) single-organism nuclear import(GO:1902593)
0.1 2.1 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.1 15.9 GO:0016197 endosomal transport(GO:0016197)
0.1 3.0 GO:0006513 protein monoubiquitination(GO:0006513)
0.1 1.3 GO:0006265 DNA topological change(GO:0006265)
0.1 0.9 GO:0006842 tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
0.1 0.3 GO:0043504 mitochondrial DNA repair(GO:0043504)
0.1 3.1 GO:0030488 tRNA methylation(GO:0030488)
0.1 1.1 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.1 2.7 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.1 2.2 GO:0032786 positive regulation of DNA-templated transcription, elongation(GO:0032786)
0.1 1.3 GO:0046549 retinal cone cell development(GO:0046549)
0.1 7.1 GO:0007030 Golgi organization(GO:0007030)
0.1 4.9 GO:0016575 histone deacetylation(GO:0016575)
0.1 3.2 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.1 1.1 GO:0051382 kinetochore assembly(GO:0051382)
0.1 3.5 GO:0000187 activation of MAPK activity(GO:0000187)
0.1 9.3 GO:0006821 chloride transport(GO:0006821)
0.1 1.0 GO:0060325 face morphogenesis(GO:0060325)
0.1 1.2 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.1 2.7 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.1 3.3 GO:0031647 regulation of protein stability(GO:0031647)
0.1 1.6 GO:0052646 alditol phosphate metabolic process(GO:0052646)
0.1 0.2 GO:0045724 positive regulation of cilium assembly(GO:0045724)
0.1 3.9 GO:0055088 lipid homeostasis(GO:0055088)
0.1 1.0 GO:0007020 microtubule nucleation(GO:0007020)
0.1 1.7 GO:0006094 gluconeogenesis(GO:0006094)
0.1 1.5 GO:0045332 phospholipid translocation(GO:0045332)
0.1 0.7 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.1 2.3 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.1 3.2 GO:0032147 activation of protein kinase activity(GO:0032147)
0.0 0.3 GO:0098935 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937) anterograde dendritic transport of neurotransmitter receptor complex(GO:0098971) axo-dendritic protein transport(GO:0099640)
0.0 0.8 GO:0072698 protein localization to microtubule cytoskeleton(GO:0072698)
0.0 2.5 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.0 0.3 GO:0071340 skeletal muscle acetylcholine-gated channel clustering(GO:0071340)
0.0 1.0 GO:0048168 regulation of neuronal synaptic plasticity(GO:0048168)
0.0 3.1 GO:0008033 tRNA processing(GO:0008033)
0.0 0.1 GO:1903966 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.0 1.1 GO:0007340 acrosome reaction(GO:0007340)
0.0 1.4 GO:0034111 negative regulation of homotypic cell-cell adhesion(GO:0034111) negative regulation of T cell activation(GO:0050868) negative regulation of leukocyte cell-cell adhesion(GO:1903038)
0.0 0.8 GO:0097192 signal transduction in absence of ligand(GO:0038034) extrinsic apoptotic signaling pathway in absence of ligand(GO:0097192)
0.0 0.3 GO:1905066 regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066)
0.0 3.4 GO:0060027 convergent extension involved in gastrulation(GO:0060027)
0.0 0.7 GO:0032482 Rab protein signal transduction(GO:0032482)
0.0 0.8 GO:1901264 carbohydrate derivative transport(GO:1901264)
0.0 2.0 GO:0090504 epiboly(GO:0090504)
0.0 7.8 GO:0007265 Ras protein signal transduction(GO:0007265)
0.0 1.5 GO:0007528 neuromuscular junction development(GO:0007528)
0.0 2.3 GO:0008285 negative regulation of cell proliferation(GO:0008285)
0.0 1.0 GO:0032465 regulation of cytokinesis(GO:0032465)
0.0 0.9 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.5 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 2.4 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 0.1 GO:0060055 angiogenesis involved in wound healing(GO:0060055)
0.0 1.3 GO:0045089 positive regulation of innate immune response(GO:0045089)
0.0 4.7 GO:0000377 RNA splicing, via transesterification reactions(GO:0000375) RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)
0.0 0.6 GO:0043491 protein kinase B signaling(GO:0043491)
0.0 2.2 GO:0007264 small GTPase mediated signal transduction(GO:0007264)
0.0 0.9 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 0.7 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 1.3 GO:1901653 cellular response to peptide hormone stimulus(GO:0071375) cellular response to peptide(GO:1901653)
0.0 8.9 GO:0098609 cell-cell adhesion(GO:0098609)
0.0 2.8 GO:0006631 fatty acid metabolic process(GO:0006631)
0.0 0.7 GO:0090090 negative regulation of canonical Wnt signaling pathway(GO:0090090)
0.0 0.8 GO:0060026 convergent extension(GO:0060026)
0.0 0.0 GO:0097510 base-excision repair, AP site formation via deaminated base removal(GO:0097510)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 4.5 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.9 1.8 GO:0032584 growth cone membrane(GO:0032584)
0.8 6.8 GO:0070552 BRISC complex(GO:0070552)
0.8 4.0 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.8 4.7 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.6 3.6 GO:0005784 Sec61 translocon complex(GO:0005784)
0.6 3.6 GO:0030870 Mre11 complex(GO:0030870)
0.5 6.9 GO:0071782 endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827)
0.5 1.5 GO:1990745 EARP complex(GO:1990745)
0.5 1.5 GO:0031166 integral component of vacuolar membrane(GO:0031166) intrinsic component of vacuolar membrane(GO:0031310)
0.5 2.8 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.5 2.3 GO:0018444 translation release factor complex(GO:0018444)
0.4 3.1 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.4 2.7 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.4 2.7 GO:0034715 pICln-Sm protein complex(GO:0034715)
0.4 1.5 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.4 3.3 GO:0032021 NELF complex(GO:0032021)
0.3 3.1 GO:0071797 LUBAC complex(GO:0071797)
0.3 7.1 GO:0044665 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.3 0.9 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.3 2.3 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.2 2.2 GO:0019908 cyclin/CDK positive transcription elongation factor complex(GO:0008024) nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908)
0.2 6.2 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.2 1.1 GO:1990131 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.2 4.9 GO:0070822 Sin3-type complex(GO:0070822)
0.2 1.1 GO:0071005 U2-type precatalytic spliceosome(GO:0071005)
0.2 2.5 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.2 2.9 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.2 7.3 GO:0016605 PML body(GO:0016605)
0.2 1.2 GO:0031371 ubiquitin conjugating enzyme complex(GO:0031371)
0.2 6.4 GO:0035097 histone methyltransferase complex(GO:0035097)
0.1 3.0 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 2.3 GO:0000178 exosome (RNase complex)(GO:0000178)
0.1 2.4 GO:0000813 ESCRT I complex(GO:0000813)
0.1 2.2 GO:0015030 Cajal body(GO:0015030)
0.1 0.5 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.1 4.5 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.1 4.8 GO:0005901 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.1 2.4 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.1 4.1 GO:0005758 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.1 5.7 GO:0000922 spindle pole(GO:0000922)
0.1 2.5 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.1 0.2 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.1 4.6 GO:0001726 ruffle(GO:0001726)
0.1 7.2 GO:0030027 lamellipodium(GO:0030027)
0.1 2.0 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 1.0 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1 2.7 GO:0005637 nuclear inner membrane(GO:0005637)
0.1 6.2 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.1 2.6 GO:0031902 late endosome membrane(GO:0031902)
0.1 8.7 GO:0005769 early endosome(GO:0005769)
0.1 0.3 GO:1990513 CLOCK-BMAL transcription complex(GO:1990513)
0.0 0.7 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.8 GO:0030315 T-tubule(GO:0030315)
0.0 2.8 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 3.1 GO:0072686 mitotic spindle(GO:0072686)
0.0 2.8 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.7 GO:0043189 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 1.0 GO:0005795 Golgi stack(GO:0005795)
0.0 1.0 GO:0031941 filamentous actin(GO:0031941)
0.0 4.6 GO:0014069 postsynaptic density(GO:0014069)
0.0 2.6 GO:0030136 clathrin-coated vesicle(GO:0030136)
0.0 0.8 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.0 1.4 GO:0098857 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 3.7 GO:0016607 nuclear speck(GO:0016607)
0.0 0.3 GO:0017119 Golgi transport complex(GO:0017119)
0.0 12.3 GO:0000139 Golgi membrane(GO:0000139)
0.0 11.9 GO:0005794 Golgi apparatus(GO:0005794)
0.0 7.4 GO:0005912 adherens junction(GO:0005912)
0.0 2.9 GO:0016324 apical plasma membrane(GO:0016324)
0.0 3.9 GO:0005681 spliceosomal complex(GO:0005681)
0.0 3.0 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 0.9 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 6.2 GO:0000785 chromatin(GO:0000785)
0.0 1.3 GO:0005770 late endosome(GO:0005770)
0.0 1.0 GO:0016592 mediator complex(GO:0016592)
0.0 0.4 GO:0071565 nBAF complex(GO:0071565)
0.0 4.3 GO:0005730 nucleolus(GO:0005730)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 6.8 GO:0070905 glycine hydroxymethyltransferase activity(GO:0004372) serine binding(GO:0070905)
1.8 5.3 GO:0080122 coenzyme A transmembrane transporter activity(GO:0015228) adenosine 3',5'-bisphosphate transmembrane transporter activity(GO:0071077) AMP transmembrane transporter activity(GO:0080122)
1.7 13.4 GO:0004849 uridine kinase activity(GO:0004849)
1.2 4.7 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
1.1 4.5 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
1.1 3.2 GO:0003985 acetyl-CoA C-acetyltransferase activity(GO:0003985)
1.0 4.0 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
1.0 4.0 GO:0043734 oxidative DNA demethylase activity(GO:0035516) DNA-N1-methyladenine dioxygenase activity(GO:0043734) RNA N6-methyladenosine dioxygenase activity(GO:1990931)
1.0 4.8 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.9 10.2 GO:0015385 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.9 3.7 GO:0047464 heparosan-N-sulfate-glucuronate 5-epimerase activity(GO:0047464)
0.9 4.3 GO:0004307 diacylglycerol cholinephosphotransferase activity(GO:0004142) ethanolaminephosphotransferase activity(GO:0004307)
0.8 3.3 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.8 4.6 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.6 2.3 GO:0008169 C-methyltransferase activity(GO:0008169)
0.6 6.2 GO:0000217 DNA secondary structure binding(GO:0000217)
0.6 1.7 GO:0004736 pyruvate carboxylase activity(GO:0004736)
0.5 2.6 GO:0070412 R-SMAD binding(GO:0070412)
0.5 9.3 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.5 4.1 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.5 3.1 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.5 4.1 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.4 2.2 GO:0032183 SUMO binding(GO:0032183)
0.4 3.9 GO:0097001 sphingolipid binding(GO:0046625) ceramide binding(GO:0097001)
0.4 2.9 GO:0030274 LIM domain binding(GO:0030274)
0.4 2.0 GO:0008469 histone-arginine N-methyltransferase activity(GO:0008469)
0.4 4.4 GO:0003691 double-stranded telomeric DNA binding(GO:0003691)
0.4 1.2 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.4 7.2 GO:0072542 phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542)
0.4 3.3 GO:0008483 transaminase activity(GO:0008483)
0.4 3.3 GO:0016838 carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.3 6.5 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.3 1.3 GO:0033149 FFAT motif binding(GO:0033149)
0.3 1.9 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.3 2.7 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.3 1.2 GO:0004379 glycylpeptide N-tetradecanoyltransferase activity(GO:0004379)
0.3 1.5 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.3 2.9 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.3 2.0 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.3 2.1 GO:0034452 dynactin binding(GO:0034452)
0.2 3.0 GO:0005158 insulin receptor binding(GO:0005158)
0.2 2.3 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.2 2.5 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.2 2.5 GO:0004309 exopolyphosphatase activity(GO:0004309)
0.2 1.1 GO:0030620 U2 snRNA binding(GO:0030620)
0.2 1.5 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.2 1.7 GO:0008410 CoA-transferase activity(GO:0008410)
0.2 4.6 GO:0004065 arylsulfatase activity(GO:0004065)
0.2 3.5 GO:0008301 DNA binding, bending(GO:0008301)
0.2 5.7 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.2 4.1 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.2 1.5 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.2 1.9 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.2 4.0 GO:0031267 small GTPase binding(GO:0031267)
0.2 4.1 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.2 8.2 GO:0017022 myosin binding(GO:0017022)
0.2 3.1 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.2 2.2 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.2 3.0 GO:0070566 adenylyltransferase activity(GO:0070566)
0.2 2.6 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.2 4.7 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.2 0.9 GO:0015142 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.2 0.6 GO:0048531 glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity(GO:0016263) beta-1,3-galactosyltransferase activity(GO:0048531)
0.2 3.0 GO:0097602 cullin family protein binding(GO:0097602)
0.1 1.1 GO:0048019 receptor antagonist activity(GO:0048019)
0.1 0.7 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.1 2.9 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.1 3.2 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.1 1.2 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.1 3.6 GO:0005246 calcium channel regulator activity(GO:0005246)
0.1 7.8 GO:0030170 pyridoxal phosphate binding(GO:0030170)
0.1 2.3 GO:0035497 cAMP response element binding(GO:0035497)
0.1 0.4 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.1 3.0 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.1 4.3 GO:0000049 tRNA binding(GO:0000049)
0.1 2.3 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.1 0.3 GO:0000703 oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity(GO:0000703)
0.1 6.3 GO:0046332 SMAD binding(GO:0046332)
0.1 5.2 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.1 1.1 GO:0052794 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.1 0.7 GO:0033592 RNA strand annealing activity(GO:0033592) RNA strand-exchange activity(GO:0034057)
0.1 4.9 GO:0042826 histone deacetylase binding(GO:0042826)
0.1 4.5 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1 2.8 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.1 1.8 GO:0010181 FMN binding(GO:0010181)
0.1 2.2 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.1 2.3 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.1 0.9 GO:0030544 Hsp70 protein binding(GO:0030544)
0.1 1.0 GO:0043015 gamma-tubulin binding(GO:0043015)
0.1 9.6 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.1 0.7 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.6 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.0 4.5 GO:1901981 phosphatidylinositol phosphate binding(GO:1901981)
0.0 2.3 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 2.4 GO:0005178 integrin binding(GO:0005178)
0.0 0.3 GO:0070888 E-box binding(GO:0070888)
0.0 0.8 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.8 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.3 GO:0008297 single-stranded DNA exodeoxyribonuclease activity(GO:0008297)
0.0 0.8 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 0.1 GO:0004768 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215) palmitoyl-CoA 9-desaturase activity(GO:0032896)
0.0 2.5 GO:0051213 dioxygenase activity(GO:0051213)
0.0 4.6 GO:0016874 ligase activity(GO:0016874)
0.0 0.5 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 1.9 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 0.7 GO:0035064 methylated histone binding(GO:0035064)
0.0 1.4 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.2 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 4.6 GO:0003729 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 6.8 GO:0046983 protein dimerization activity(GO:0046983)
0.0 7.3 GO:0005525 GTP binding(GO:0005525)
0.0 0.3 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 3.6 GO:0051015 actin filament binding(GO:0051015)
0.0 0.2 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors(GO:0016627)
0.0 0.9 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 4.1 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.3 2.2 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.2 8.3 PID ATM PATHWAY ATM pathway
0.2 7.8 PID AURORA B PATHWAY Aurora B signaling
0.2 5.8 PID MYC PATHWAY C-MYC pathway
0.2 2.3 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1 3.3 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.1 6.3 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.1 3.6 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 1.1 PID REELIN PATHWAY Reelin signaling pathway
0.1 6.1 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.1 3.7 PID RAC1 PATHWAY RAC1 signaling pathway
0.1 1.7 PID FANCONI PATHWAY Fanconi anemia pathway
0.1 1.4 PID SHP2 PATHWAY SHP2 signaling
0.1 1.8 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.1 2.1 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 3.5 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 1.1 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 0.4 PID RHOA REG PATHWAY Regulation of RhoA activity

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 7.8 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.6 6.3 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.5 3.8 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.4 4.8 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.4 4.8 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.3 1.7 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.3 3.6 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.3 4.1 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.3 4.3 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.3 3.0 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.2 7.1 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.2 2.2 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.2 11.2 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.2 4.7 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.2 1.4 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.2 4.1 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.2 3.6 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.2 3.2 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.1 11.2 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.1 2.7 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1 1.2 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.1 2.3 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.1 1.7 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.1 1.2 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.1 4.8 REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION Genes involved in Cyclin E associated events during G1/S transition
0.1 2.0 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.1 1.8 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.1 1.1 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.1 2.4 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.1 3.7 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.1 3.0 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.1 6.1 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.1 1.3 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.1 1.5 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 1.1 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 1.4 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 0.3 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 1.5 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.3 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 3.3 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.9 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 1.0 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.6 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.4 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 1.5 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases