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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for CABZ01087224.1+hlfb

Z-value: 0.69

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Transcription factors associated with CABZ01087224.1+hlfb

Gene Symbol Gene ID Gene Info
hlfb
ENSDARG00000061011 HLF transcription factor, PAR bZIP family member b
CABZ01087224.1
ENSDARG00000111269 ENSDARG00000111269

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
CABZ01087224.1dr11_v1_chr3_+_11568523_115685230.155.4e-01Click!
hlfbdr11_v1_chr12_+_32159272_321592720.087.6e-01Click!

Activity profile of CABZ01087224.1+hlfb motif

Sorted Z-values of CABZ01087224.1+hlfb motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr5_+_22974019 3.56 ENSDART00000147157
ENSDART00000020434
brwd3
bromodomain and WD repeat domain containing 3
chr25_+_36292465 2.24 ENSDART00000152649
bmb
brambleberry
chr3_+_7763114 1.93 ENSDART00000057434
hook2
hook microtubule-tethering protein 2
chr3_-_26184018 1.87 ENSDART00000191604
si:ch211-11k18.4
si:ch211-11k18.4
chr7_+_46020508 1.84 ENSDART00000170294
ccne1
cyclin E1
chr16_-_29387215 1.77 ENSDART00000148787
s100a1
S100 calcium binding protein A1
chr2_+_35603637 1.75 ENSDART00000147278
plk3
polo-like kinase 3 (Drosophila)
chr19_+_7549854 1.67 ENSDART00000138866
ENSDART00000151758
pbxip1a
pre-B-cell leukemia homeobox interacting protein 1a
chr2_-_17115256 1.65 ENSDART00000190488
pif1
PIF1 5'-to-3' DNA helicase homolog (S. cerevisiae)
chr7_+_46019780 1.54 ENSDART00000163991
ccne1
cyclin E1
chr14_+_3507326 1.49 ENSDART00000159326
gstp1
glutathione S-transferase pi 1
chr1_+_16600690 1.48 ENSDART00000162164
mtus1b
microtubule associated tumor suppressor 1b
chr3_-_26183699 1.46 ENSDART00000147517
ENSDART00000140731
si:ch211-11k18.4
si:ch211-11k18.4
chr1_+_12394205 1.46 ENSDART00000138622
ENSDART00000136421
ENSDART00000139440
ENSDART00000184296
ENSDART00000008127
zgc:77739
zgc:77739
chr14_+_21699129 1.40 ENSDART00000073707
stx3a
syntaxin 3A
chr22_-_817479 1.40 ENSDART00000123487
zgc:153675
zgc:153675
chr7_+_38380135 1.37 ENSDART00000174005
rhpn2
rhophilin, Rho GTPase binding protein 2
chr13_+_25396896 1.37 ENSDART00000041257
gsto2
glutathione S-transferase omega 2
chr6_+_10333920 1.36 ENSDART00000151667
ENSDART00000151477
cobll1a
cordon-bleu WH2 repeat protein-like 1a
chr6_-_4228640 1.33 ENSDART00000162497
ENSDART00000179923
trak2
trafficking protein, kinesin binding 2
chr13_+_25397098 1.33 ENSDART00000132953
gsto2
glutathione S-transferase omega 2
chr15_+_12435975 1.31 ENSDART00000168011
tmprss4a
transmembrane protease, serine 4a
chr3_+_43373867 1.30 ENSDART00000159455
ENSDART00000172425
zfand2a
zinc finger, AN1-type domain 2A
chr13_-_25408387 1.30 ENSDART00000002741
itprip
inositol 1,4,5-trisphosphate receptor interacting protein
chr8_-_25846188 1.30 ENSDART00000128829
efhd2
EF-hand domain family, member D2
chr23_-_12453700 1.29 ENSDART00000091140
snx21
sorting nexin family member 21
chr1_-_354115 1.28 ENSDART00000141590
ENSDART00000098627
pros1
protein S
chr6_+_23810529 1.27 ENSDART00000166921
glulb
glutamate-ammonia ligase (glutamine synthase) b
chr9_-_12888082 1.25 ENSDART00000133135
ENSDART00000134415
si:ch211-167j6.3
si:ch211-167j6.3
chr4_-_1757460 1.24 ENSDART00000144074
tm7sf3
transmembrane 7 superfamily member 3
chr17_+_25833947 1.23 ENSDART00000044328
ENSDART00000154604
acss1
acyl-CoA synthetase short chain family member 1
chr4_-_27099224 1.22 ENSDART00000048383
creld2
cysteine-rich with EGF-like domains 2
chr6_+_8314451 1.20 ENSDART00000147793
ENSDART00000183688
gcdha
glutaryl-CoA dehydrogenase a
chr17_-_43031763 1.19 ENSDART00000132754
ENSDART00000050399
npc2
Niemann-Pick disease, type C2
chr5_-_48070779 1.16 ENSDART00000078401
tmem161b
transmembrane protein 161B
chr16_+_47207691 1.15 ENSDART00000062507
ica1
islet cell autoantigen 1
chr2_+_44518636 1.15 ENSDART00000153733
pask
PAS domain containing serine/threonine kinase
chr3_-_30885250 1.14 ENSDART00000109104
kmt5c
lysine methyltransferase 5C
chr9_+_27720428 1.14 ENSDART00000112415
lcmt2
leucine carboxyl methyltransferase 2
chr13_-_25196758 1.13 ENSDART00000184722
adka
adenosine kinase a
chr4_+_5196469 1.13 ENSDART00000067386
rad51ap1
RAD51 associated protein 1
chr13_+_15816573 1.11 ENSDART00000137061
klc1a
kinesin light chain 1a
chr14_+_21699414 1.09 ENSDART00000169942
stx3a
syntaxin 3A
chr5_-_33236637 1.09 ENSDART00000085512
ENSDART00000144694
kank1b
KN motif and ankyrin repeat domains 1b
chr19_-_12965020 1.09 ENSDART00000128975
slc25a32a
solute carrier family 25 (mitochondrial folate carrier), member 32a
chr24_+_37338169 1.08 ENSDART00000141771
gnptg
N-acetylglucosamine-1-phosphate transferase, gamma subunit
chr20_-_48877458 1.08 ENSDART00000163271
xrn2
5'-3' exoribonuclease 2
chr22_+_786556 1.07 ENSDART00000125347
cry1bb
cryptochrome circadian clock 1bb
chr17_+_51744450 1.06 ENSDART00000190955
ENSDART00000149807
odc1
ornithine decarboxylase 1
chr1_+_19764995 1.06 ENSDART00000138276
si:ch211-42i9.8
si:ch211-42i9.8
chr2_+_16597011 1.06 ENSDART00000160641
ENSDART00000125413
xrn1
5'-3' exoribonuclease 1
chr5_-_69212184 1.04 ENSDART00000053963
mat2ab
methionine adenosyltransferase II, alpha b
chr4_+_5341592 1.02 ENSDART00000123375
ENSDART00000067371
zgc:113263
zgc:113263
chr17_-_17759138 1.01 ENSDART00000157128
ENSDART00000123845
adck1
aarF domain containing kinase 1
chr20_-_23876291 1.01 ENSDART00000043316
katna1
katanin p60 (ATPase containing) subunit A 1
chr9_-_21238159 1.00 ENSDART00000146764
ENSDART00000102143
cox17
COX17 cytochrome c oxidase copper chaperone
chr13_+_30035253 0.99 ENSDART00000181303
ENSDART00000057525
ENSDART00000136622
dnajb12a
DnaJ (Hsp40) homolog, subfamily B, member 12a
chr6_+_8315050 0.99 ENSDART00000189987
gcdha
glutaryl-CoA dehydrogenase a
chr23_-_35396845 0.99 ENSDART00000142038
ENSDART00000049373
ENSDART00000181978
ENSDART00000171357
cmtr1
cap methyltransferase 1
chr10_+_39283985 0.97 ENSDART00000016464
dcps
decapping enzyme, scavenger
chr5_+_27137473 0.97 ENSDART00000181833
unc5db
unc-5 netrin receptor Db
chr22_+_11756040 0.96 ENSDART00000105808
krt97
keratin 97
chr15_-_1885247 0.95 ENSDART00000149703
porb
P450 (cytochrome) oxidoreductase b
chr2_-_55779927 0.94 ENSDART00000168579
CABZ01066725.1

chr7_-_8961941 0.94 ENSDART00000111002
si:ch211-74f19.2
si:ch211-74f19.2
chr9_+_32178050 0.94 ENSDART00000169526
coq10b
coenzyme Q10B
chr18_-_15551360 0.93 ENSDART00000159915
ENSDART00000172690
ppfibp1b
PTPRF interacting protein, binding protein 1b (liprin beta 1)
chr17_+_17764979 0.93 ENSDART00000105013
alkbh1
alkB homolog 1, histone H2A dioxygenase
chr14_-_30905288 0.93 ENSDART00000173449
ENSDART00000173451
si:ch211-126c2.4
si:ch211-126c2.4
chr7_+_67733759 0.92 ENSDART00000172015
cyb5b
cytochrome b5 type B
chr23_-_33361425 0.92 ENSDART00000031638
slc48a1a
solute carrier family 48 (heme transporter), member 1a
chr3_+_24094581 0.92 ENSDART00000138270
ENSDART00000131509
copz2
coatomer protein complex, subunit zeta 2
chr24_-_37338162 0.91 ENSDART00000056303
tsr3
TSR3, 20S rRNA accumulation, homolog (S. cerevisiae)
chr2_-_4070850 0.91 ENSDART00000159990
yme1l1b
YME1-like 1b
chr8_-_21103522 0.91 ENSDART00000100283
aldh9a1a.1
aldehyde dehydrogenase 9 family, member A1a, tandem duplicate 1
chr17_+_26722904 0.89 ENSDART00000114927
nrde2
NRDE-2, necessary for RNA interference, domain containing
chr9_-_32300783 0.89 ENSDART00000078596
hspd1
heat shock 60 protein 1
chr8_-_21103041 0.88 ENSDART00000171771
ENSDART00000131322
ENSDART00000137838
aldh9a1a.1
aldehyde dehydrogenase 9 family, member A1a, tandem duplicate 1
chr20_-_35508805 0.87 ENSDART00000169538
adgrf3b
adhesion G protein-coupled receptor F3b
chr12_+_3571770 0.87 ENSDART00000164707
ENSDART00000189819
coa3a
cytochrome C oxidase assembly factor 3a
chr12_+_19199735 0.86 ENSDART00000066393
pdap1a
pdgfa associated protein 1a
chr2_-_19234329 0.86 ENSDART00000161106
ENSDART00000160060
ENSDART00000174552
cdc20
cell division cycle 20 homolog
chr20_+_38201644 0.84 ENSDART00000022694
ehd3
EH-domain containing 3
chr5_-_54395488 0.84 ENSDART00000160781
zmynd19
zinc finger, MYND-type containing 19
chr23_+_33963619 0.84 ENSDART00000140666
ENSDART00000084792
plpbp
pyridoxal phosphate binding protein
chr11_-_34572202 0.84 ENSDART00000077883
pfkfb4a
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4a
chr21_+_43178831 0.84 ENSDART00000151512
aff4
AF4/FMR2 family, member 4
chr8_-_11324143 0.84 ENSDART00000008215
pip5k1bb
phosphatidylinositol-4-phosphate 5-kinase, type I, beta b
chr25_+_3104959 0.83 ENSDART00000167130
rab3il1
RAB3A interacting protein (rabin3)-like 1
chr8_+_26874924 0.82 ENSDART00000141794
rimkla
ribosomal modification protein rimK-like family member A
chr12_+_46869271 0.82 ENSDART00000166560
hpdl
4-hydroxyphenylpyruvate dioxygenase-like
chr21_+_17051478 0.81 ENSDART00000047201
ENSDART00000161650
ENSDART00000167298
atp2a2a
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2a
chr24_-_17023392 0.80 ENSDART00000106058
ptgdsb.2
prostaglandin D2 synthase b, tandem duplicate 2
chr21_+_18907102 0.80 ENSDART00000160185
ENSDART00000190175
ENSDART00000017937
ENSDART00000191546
ENSDART00000130519
ENSDART00000137143
smpd4
sphingomyelin phosphodiesterase 4
chr6_+_3716666 0.79 ENSDART00000041627
ssb
Sjogren syndrome antigen B (autoantigen La)
chr15_-_20412286 0.79 ENSDART00000008589
chp2
calcineurin-like EF-hand protein 2
chr7_+_22792895 0.79 ENSDART00000184407
rbm4.3
RNA binding motif protein 4.3
chr15_+_24676905 0.79 ENSDART00000078014
ENSDART00000143137
poldip2
polymerase (DNA-directed), delta interacting protein 2
chr8_-_21110233 0.78 ENSDART00000127371
ENSDART00000100276
tmco1
transmembrane and coiled-coil domains 1
chr14_+_1170968 0.78 ENSDART00000125203
ENSDART00000193575
hopx
HOP homeobox
chr3_+_25907266 0.78 ENSDART00000170324
ENSDART00000192633
tom1
target of myb1 membrane trafficking protein
chr3_+_41731527 0.78 ENSDART00000049007
ENSDART00000187866
chst12a
carbohydrate (chondroitin 4) sulfotransferase 12a
chr23_+_9522781 0.77 ENSDART00000136486
osbpl2b
oxysterol binding protein-like 2b
chr1_+_49415281 0.76 ENSDART00000015007
taf5
TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr5_-_40292299 0.76 ENSDART00000097525
snx18a
sorting nexin 18a
chr2_-_54387550 0.76 ENSDART00000097388
napgb
N-ethylmaleimide-sensitive factor attachment protein, gamma b
chr18_+_25546227 0.76 ENSDART00000085824
pex11a
peroxisomal biogenesis factor 11 alpha
chr18_+_8917766 0.75 ENSDART00000145226
si:ch211-233h19.2
si:ch211-233h19.2
chr22_-_17677947 0.75 ENSDART00000139911
tjp3
tight junction protein 3
chr16_-_19568388 0.75 ENSDART00000141616
abcb5
ATP-binding cassette, sub-family B (MDR/TAP), member 5
chr7_+_73295890 0.75 ENSDART00000174331
ENSDART00000174250
CABZ01083442.1

chr20_-_30035326 0.74 ENSDART00000141068
sox11b
SRY (sex determining region Y)-box 11b
chr16_-_35427060 0.73 ENSDART00000172294
ctps1b
CTP synthase 1b
chr5_+_29831235 0.72 ENSDART00000109660
f11r.1
F11 receptor, tandem duplicate 1
chr19_+_26923110 0.72 ENSDART00000149988
nelfe
negative elongation factor complex member E
chr5_-_69716501 0.72 ENSDART00000158956
mob1a
MOB kinase activator 1A
chr25_-_34845302 0.71 ENSDART00000039485
gabarapl2
GABA(A) receptor-associated protein like 2
chr16_+_33143503 0.71 ENSDART00000058471
ENSDART00000179385
rhbdl2
rhomboid, veinlet-like 2 (Drosophila)
chr11_+_43751263 0.71 ENSDART00000163843
zgc:153431
zgc:153431
chr5_-_11809404 0.70 ENSDART00000132564
nf2a
neurofibromin 2a (merlin)
chr11_+_13176568 0.70 ENSDART00000125371
ENSDART00000123257
mknk1
MAP kinase interacting serine/threonine kinase 1
chr24_-_26854032 0.68 ENSDART00000087991
fndc3bb
fibronectin type III domain containing 3Bb
chr24_+_32525146 0.68 ENSDART00000132417
ENSDART00000110185
yme1l1a
YME1-like 1a
chr24_+_37338757 0.67 ENSDART00000182543
gnptg
N-acetylglucosamine-1-phosphate transferase, gamma subunit
chr18_-_14879135 0.67 ENSDART00000099701
selenoo1
selenoprotein O1
chr14_-_5642371 0.66 ENSDART00000183859
ENSDART00000054876
npm1b
nucleophosmin 1b
chr7_-_40959667 0.66 ENSDART00000084070
rbm33a
RNA binding motif protein 33a
chr15_+_21712328 0.66 ENSDART00000192553
NKAPD1
zgc:162339
chr23_-_29812667 0.65 ENSDART00000006120
pik3cd
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
chr8_-_53044300 0.65 ENSDART00000191653
nr6a1a
nuclear receptor subfamily 6, group A, member 1a
chr16_-_43139251 0.64 ENSDART00000021145
ENSDART00000165293
slc25a40
solute carrier family 25, member 40
chr10_-_39283883 0.64 ENSDART00000023831
cry5
cryptochrome circadian clock 5
chr17_-_22573311 0.63 ENSDART00000141523
ENSDART00000140022
ENSDART00000079390
ENSDART00000188644
exo1
exonuclease 1
chr18_+_17493859 0.63 ENSDART00000090754
si:dkey-102f14.5
si:dkey-102f14.5
chr24_-_37338739 0.62 ENSDART00000146844
tsr3
TSR3, 20S rRNA accumulation, homolog (S. cerevisiae)
chr22_+_11775269 0.62 ENSDART00000140272
krt96
keratin 96
chr12_+_13205955 0.61 ENSDART00000092906
ppp1cab
protein phosphatase 1, catalytic subunit, alpha isozyme b
chr3_+_19687217 0.61 ENSDART00000141937
tlk2
tousled-like kinase 2
chr13_+_26703922 0.60 ENSDART00000020946
fancl
Fanconi anemia, complementation group L
chr8_+_247163 0.60 ENSDART00000122378
cep120
centrosomal protein 120
chr3_+_30921246 0.60 ENSDART00000076850
cldni
claudin i
chr5_-_51998708 0.60 ENSDART00000097194
serinc5
serine incorporator 5
chr5_+_26921033 0.60 ENSDART00000051483
tm2d2
TM2 domain containing 2
chr13_-_15142280 0.58 ENSDART00000163132
rab11fip5a
RAB11 family interacting protein 5a (class I)
chr3_+_1107102 0.58 ENSDART00000092690
srebf2
sterol regulatory element binding transcription factor 2
chr2_-_37277626 0.58 ENSDART00000135340
nadkb
NAD kinase b
chr20_-_33675676 0.57 ENSDART00000147168
rock2b
rho-associated, coiled-coil containing protein kinase 2b
chr21_-_32781612 0.57 ENSDART00000031028
cnot6a
CCR4-NOT transcription complex, subunit 6a
chr24_+_11908833 0.57 ENSDART00000178622
fen1
flap structure-specific endonuclease 1
chr9_-_21268576 0.57 ENSDART00000080604
sap18
Sin3A-associated protein
chr12_-_23365737 0.57 ENSDART00000170376
mpp7a
membrane protein, palmitoylated 7a (MAGUK p55 subfamily member 7)
chr19_+_42227400 0.56 ENSDART00000131574
ENSDART00000135436
jtb
jumping translocation breakpoint
chr14_+_6962271 0.56 ENSDART00000148447
ENSDART00000149114
ENSDART00000149492
ENSDART00000148394
hnrnpaba
heterogeneous nuclear ribonucleoprotein A/Ba
chr8_-_28274251 0.56 ENSDART00000050671
rap1aa
RAP1A, member of RAS oncogene family a
chr8_-_28274552 0.56 ENSDART00000131580
rap1aa
RAP1A, member of RAS oncogene family a
chr9_+_38588081 0.55 ENSDART00000031127
ENSDART00000131784
snx4
sorting nexin 4
chr12_-_22400999 0.54 ENSDART00000153194
si:dkey-38p12.3
si:dkey-38p12.3
chr2_+_44348473 0.54 ENSDART00000155166
ENSDART00000098146
zgc:152670
zgc:152670
chr19_-_34970312 0.54 ENSDART00000102896
ndrg1a
N-myc downstream regulated 1a
chr6_-_26895750 0.54 ENSDART00000011863
hdlbpa
high density lipoprotein binding protein a
chr2_+_3044992 0.54 ENSDART00000020463
zgc:63882
zgc:63882
chr17_+_35243753 0.54 ENSDART00000016702
iah1
isoamyl acetate hydrolyzing esterase 1 (putative)
chr10_+_18877362 0.53 ENSDART00000138334
ppp2r2ab
protein phosphatase 2, regulatory subunit B, alpha b
chr3_-_52899394 0.53 ENSDART00000128223
CHCHD5
coiled-coil-helix-coiled-coil-helix domain containing 5
chr12_-_34258384 0.53 ENSDART00000109196
pgs1
phosphatidylglycerophosphate synthase 1
chr14_+_7377552 0.52 ENSDART00000142158
ENSDART00000141471
hars
histidyl-tRNA synthetase
chr19_+_15440841 0.52 ENSDART00000182329
lin28a
lin-28 homolog A (C. elegans)
chr16_+_41015781 0.52 ENSDART00000124543
dek
DEK proto-oncogene
chr19_+_26923274 0.52 ENSDART00000148439
ENSDART00000148877
nelfe
negative elongation factor complex member E
chr24_+_11908480 0.51 ENSDART00000024224
fen1
flap structure-specific endonuclease 1
chr13_-_10620652 0.51 ENSDART00000135000
ENSDART00000191587
si:ch73-54n14.2
camkmt
si:ch73-54n14.2
calmodulin-lysine N-methyltransferase
chr25_+_6122823 0.51 ENSDART00000191824
ENSDART00000067514
rbpms2a
RNA binding protein with multiple splicing 2a
chr2_+_30182431 0.51 ENSDART00000004903
rdh10b
retinol dehydrogenase 10b
chr7_-_21887104 0.51 ENSDART00000019699
mettl3
methyltransferase like 3
chr23_-_36441693 0.51 ENSDART00000024354
csad
cysteine sulfinic acid decarboxylase
chr8_-_53044089 0.51 ENSDART00000135982
nr6a1a
nuclear receptor subfamily 6, group A, member 1a
chr23_-_25686894 0.50 ENSDART00000181420
ENSDART00000088208
lrp1ab
low density lipoprotein receptor-related protein 1Ab
chr19_+_15441022 0.50 ENSDART00000098970
ENSDART00000140276
lin28a
lin-28 homolog A (C. elegans)
chr10_+_26990095 0.49 ENSDART00000064111
faub
Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed b
chr20_+_39250673 0.49 ENSDART00000153003
reps1
RALBP1 associated Eps domain containing 1
chr19_+_9032073 0.49 ENSDART00000127755
ash1l
ash1 (absent, small, or homeotic)-like (Drosophila)
chr5_+_56277866 0.49 ENSDART00000170610
ENSDART00000028854
ENSDART00000148749
aatf
apoptosis antagonizing transcription factor
chr8_+_26007988 0.49 ENSDART00000193948
ENSDART00000058100
xpc
xeroderma pigmentosum, complementation group C
chr7_+_38090515 0.49 ENSDART00000131387
cebpg
CCAAT/enhancer binding protein (C/EBP), gamma
chr5_+_43470544 0.48 ENSDART00000111587
rhobtb2a
Rho-related BTB domain containing 2a
chr9_-_13871935 0.47 ENSDART00000146597
raph1a
Ras association (RalGDS/AF-6) and pleckstrin homology domains 1a
chr9_-_9732212 0.47 ENSDART00000092884
lrrc58b
leucine rich repeat containing 58b
chr15_-_1765098 0.47 ENSDART00000149980
ENSDART00000093074
bud23
BUD23, rRNA methyltransferase and ribosome maturation factor
chr15_+_15232855 0.47 ENSDART00000033904
ENSDART00000139263
med29
mediator complex subunit 29
chr2_+_37837249 0.47 ENSDART00000113337
parp2
poly (ADP-ribose) polymerase 2
chr4_+_9178913 0.46 ENSDART00000168558
nfyba
nuclear transcription factor Y, beta a
chr17_+_26828027 0.45 ENSDART00000042060
jade1
jade family PHD finger 1
chr6_-_32411703 0.45 ENSDART00000151002
ENSDART00000078908
usp1
ubiquitin specific peptidase 1
chr9_-_32300611 0.45 ENSDART00000127938
hspd1
heat shock 60 protein 1
chr15_+_15771418 0.45 ENSDART00000153831
si:ch211-33e4.3
si:ch211-33e4.3
chr7_+_60396957 0.45 ENSDART00000121545
brms1
breast cancer metastasis suppressor 1
chr6_+_36381709 0.45 ENSDART00000004727
rhcgl1
Rh family, C glycoprotein, like 1
chr20_-_30900947 0.45 ENSDART00000153419
ENSDART00000062536
hebp2
heme binding protein 2
chr18_-_39288894 0.45 ENSDART00000186216
mapk6
mitogen-activated protein kinase 6
chr21_-_38618540 0.44 ENSDART00000036600
slc25a14
solute carrier family 25 (mitochondrial carrier, brain), member 14

Network of associatons between targets according to the STRING database.

First level regulatory network of CABZ01087224.1+hlfb

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.5 GO:0098967 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.4 2.2 GO:0007344 karyogamy(GO:0000741) pronuclear fusion(GO:0007344)
0.4 1.8 GO:0048308 organelle inheritance(GO:0048308) Golgi inheritance(GO:0048313)
0.4 1.3 GO:0042730 fibrinolysis(GO:0042730)
0.4 1.1 GO:0034773 histone H4-K20 methylation(GO:0034770) histone H4-K20 trimethylation(GO:0034773)
0.4 1.1 GO:0031591 wybutosine metabolic process(GO:0031590) wybutosine biosynthetic process(GO:0031591)
0.3 1.3 GO:0045041 positive regulation of interleukin-6 production(GO:0032755) protein import into mitochondrial intermembrane space(GO:0045041)
0.3 2.2 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.3 1.9 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.3 1.5 GO:0000455 enzyme-directed rRNA pseudouridine synthesis(GO:0000455)
0.2 1.5 GO:0080009 mRNA methylation(GO:0080009)
0.2 0.7 GO:0046689 response to mercury ion(GO:0046689) detoxification of mercury ion(GO:0050787)
0.2 1.7 GO:1905097 regulation of guanyl-nucleotide exchange factor activity(GO:1905097) regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.2 1.3 GO:0098957 anterograde axonal transport of mitochondrion(GO:0098957)
0.2 1.1 GO:0046929 negative regulation of neurotransmitter secretion(GO:0046929) response to cAMP(GO:0051591) cellular response to cAMP(GO:0071320) negative regulation of synaptic vesicle transport(GO:1902804) negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.2 0.9 GO:0070129 regulation of mitochondrial translation(GO:0070129) positive regulation of mitochondrial translation(GO:0070131)
0.2 1.2 GO:0019427 acetate metabolic process(GO:0006083) acetyl-CoA biosynthetic process from acetate(GO:0019427)
0.2 1.0 GO:0071218 response to misfolded protein(GO:0051788) cellular response to misfolded protein(GO:0071218)
0.2 1.2 GO:0032367 intracellular cholesterol transport(GO:0032367)
0.2 0.8 GO:0070987 error-free translesion synthesis(GO:0070987)
0.2 1.1 GO:0044209 AMP salvage(GO:0044209)
0.2 0.9 GO:0035513 oxidative RNA demethylation(GO:0035513)
0.2 1.3 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.2 1.1 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.2 0.6 GO:0010825 positive regulation of centrosome duplication(GO:0010825)
0.1 1.6 GO:0000002 mitochondrial genome maintenance(GO:0000002)
0.1 1.0 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.1 1.2 GO:0070874 negative regulation of glycogen biosynthetic process(GO:0045719) negative regulation of glycogen metabolic process(GO:0070874)
0.1 0.9 GO:1904668 positive regulation of ubiquitin protein ligase activity(GO:1904668)
0.1 0.4 GO:0050666 regulation of sulfur amino acid metabolic process(GO:0031335) regulation of homocysteine metabolic process(GO:0050666)
0.1 1.0 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.1 1.2 GO:1902038 positive regulation of hematopoietic stem cell differentiation(GO:1902038)
0.1 0.9 GO:0031048 chromatin silencing by small RNA(GO:0031048)
0.1 0.8 GO:0016559 peroxisome fission(GO:0016559)
0.1 1.0 GO:0051013 microtubule severing(GO:0051013)
0.1 0.4 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.1 0.5 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.1 1.1 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
0.1 0.5 GO:0036265 RNA (guanine-N7)-methylation(GO:0036265)
0.1 0.8 GO:0032469 endoplasmic reticulum calcium ion homeostasis(GO:0032469)
0.1 0.5 GO:0051145 smooth muscle cell differentiation(GO:0051145)
0.1 0.4 GO:0042754 negative regulation of circadian rhythm(GO:0042754)
0.1 0.9 GO:0015886 heme transport(GO:0015886) iron coordination entity transport(GO:1901678)
0.1 1.5 GO:0016075 rRNA catabolic process(GO:0016075)
0.1 0.4 GO:0071423 thiosulfate transport(GO:0015709) oxaloacetate transport(GO:0015729) malate transport(GO:0015743) succinate transport(GO:0015744) succinate transmembrane transport(GO:0071422) malate transmembrane transport(GO:0071423)
0.1 1.0 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.1 0.4 GO:0014005 microglia development(GO:0014005)
0.1 0.6 GO:0006741 NADP biosynthetic process(GO:0006741)
0.1 0.8 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.1 0.5 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.1 0.6 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.1 0.4 GO:0045822 negative regulation of heart contraction(GO:0045822) negative regulation of blood circulation(GO:1903523)
0.1 0.8 GO:0030104 water homeostasis(GO:0030104)
0.1 0.7 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.1 0.7 GO:0046548 retinal rod cell development(GO:0046548)
0.1 3.4 GO:1904029 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.1 0.5 GO:0032049 phosphatidylglycerol biosynthetic process(GO:0006655) cardiolipin biosynthetic process(GO:0032049)
0.1 0.2 GO:0070221 sulfide oxidation(GO:0019418) sulfide oxidation, using sulfide:quinone oxidoreductase(GO:0070221)
0.1 0.4 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.1 1.0 GO:0046688 response to copper ion(GO:0046688)
0.1 0.6 GO:0010884 positive regulation of lipid storage(GO:0010884)
0.1 1.2 GO:0050796 regulation of insulin secretion(GO:0050796)
0.1 0.8 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.1 0.7 GO:0050892 intestinal absorption(GO:0050892)
0.1 0.3 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.1 0.2 GO:1904871 positive regulation of protein localization to nucleus(GO:1900182) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871)
0.1 0.7 GO:1904356 regulation of telomere maintenance via telomere lengthening(GO:1904356)
0.0 0.3 GO:0050820 positive regulation of blood coagulation(GO:0030194) positive regulation of coagulation(GO:0050820) positive regulation of hemostasis(GO:1900048)
0.0 0.1 GO:1904983 transmembrane glycine transport from cytosol to mitochondrion(GO:1904983)
0.0 0.2 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 0.9 GO:1901663 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 0.3 GO:0030823 regulation of cGMP metabolic process(GO:0030823) positive regulation of cGMP metabolic process(GO:0030825) regulation of cGMP biosynthetic process(GO:0030826) positive regulation of cGMP biosynthetic process(GO:0030828) regulation of guanylate cyclase activity(GO:0031282) positive regulation of guanylate cyclase activity(GO:0031284)
0.0 1.2 GO:0006515 misfolded or incompletely synthesized protein catabolic process(GO:0006515)
0.0 0.7 GO:0048696 collateral sprouting in absence of injury(GO:0048669) regulation of collateral sprouting in absence of injury(GO:0048696)
0.0 0.6 GO:0006658 phosphatidylserine metabolic process(GO:0006658)
0.0 0.3 GO:0033015 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.0 0.4 GO:0031272 pseudopodium organization(GO:0031268) pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.2 GO:0003413 chondrocyte differentiation involved in endochondral bone morphogenesis(GO:0003413) growth plate cartilage chondrocyte differentiation(GO:0003418)
0.0 0.6 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 0.5 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.0 1.2 GO:0036297 interstrand cross-link repair(GO:0036297)
0.0 1.5 GO:0006749 glutathione metabolic process(GO:0006749)
0.0 0.6 GO:0043001 Golgi to plasma membrane protein transport(GO:0043001)
0.0 0.2 GO:0003232 bulbus arteriosus development(GO:0003232)
0.0 0.5 GO:0002138 retinoic acid biosynthetic process(GO:0002138)
0.0 0.8 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.0 3.7 GO:0008360 regulation of cell shape(GO:0008360)
0.0 0.5 GO:0061154 endothelial tube morphogenesis(GO:0061154) blood vessel lumenization(GO:0072554)
0.0 0.2 GO:0097010 eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.0 1.2 GO:0043966 histone H3 acetylation(GO:0043966)
0.0 0.2 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0 0.6 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 1.9 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.0 0.7 GO:0006298 mismatch repair(GO:0006298)
0.0 1.1 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 0.6 GO:1901888 regulation of cell junction assembly(GO:1901888)
0.0 0.1 GO:0015670 carbon dioxide transport(GO:0015670)
0.0 0.2 GO:0048245 eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.0 0.1 GO:0001120 DNA-templated transcriptional open complex formation(GO:0001112) transcriptional open complex formation at RNA polymerase II promoter(GO:0001113) protein-DNA complex remodeling(GO:0001120)
0.0 0.9 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.3 GO:0051877 pigment granule aggregation in cell center(GO:0051877)
0.0 1.2 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.5 GO:0019471 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471)
0.0 0.1 GO:0016322 neuron remodeling(GO:0016322)
0.0 0.1 GO:1902751 positive regulation of G2/M transition of mitotic cell cycle(GO:0010971) positive regulation of cell cycle G2/M phase transition(GO:1902751)
0.0 2.6 GO:0008016 regulation of heart contraction(GO:0008016)
0.0 0.1 GO:0043388 positive regulation of DNA binding(GO:0043388) positive regulation of binding(GO:0051099)
0.0 0.4 GO:0007004 RNA-dependent DNA biosynthetic process(GO:0006278) telomere maintenance via telomerase(GO:0007004)
0.0 0.3 GO:0006346 methylation-dependent chromatin silencing(GO:0006346) positive regulation of chromatin silencing(GO:0031937) regulation of methylation-dependent chromatin silencing(GO:0090308) positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.0 0.8 GO:0009072 aromatic amino acid family metabolic process(GO:0009072)
0.0 0.3 GO:0045670 regulation of osteoclast differentiation(GO:0045670)
0.0 1.3 GO:0000956 nuclear-transcribed mRNA catabolic process(GO:0000956)
0.0 0.1 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.3 GO:0002084 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.0 0.5 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
0.0 0.2 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.0 3.5 GO:0016197 endosomal transport(GO:0016197)
0.0 0.2 GO:0035306 positive regulation of dephosphorylation(GO:0035306) positive regulation of protein dephosphorylation(GO:0035307)
0.0 0.0 GO:0007585 respiratory gaseous exchange(GO:0007585) regulation of respiratory gaseous exchange(GO:0043576)
0.0 1.2 GO:0030917 midbrain-hindbrain boundary development(GO:0030917)
0.0 0.3 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0 0.1 GO:0097241 hematopoietic stem cell migration to bone marrow(GO:0097241)
0.0 0.2 GO:0052646 alditol phosphate metabolic process(GO:0052646)
0.0 1.3 GO:0032272 negative regulation of actin filament polymerization(GO:0030837) negative regulation of protein polymerization(GO:0032272)
0.0 0.3 GO:0031952 regulation of protein autophosphorylation(GO:0031952)
0.0 1.0 GO:0007528 neuromuscular junction development(GO:0007528)
0.0 0.8 GO:0030166 proteoglycan biosynthetic process(GO:0030166)
0.0 0.6 GO:0070830 apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830)
0.0 0.8 GO:0016575 histone deacetylation(GO:0016575)
0.0 0.2 GO:0008608 attachment of spindle microtubules to kinetochore(GO:0008608)
0.0 0.2 GO:0051897 positive regulation of protein kinase B signaling(GO:0051897)
0.0 0.0 GO:0006370 7-methylguanosine mRNA capping(GO:0006370)
0.0 0.1 GO:0002159 desmosome assembly(GO:0002159)
0.0 0.5 GO:0071391 cellular response to estrogen stimulus(GO:0071391)
0.0 0.5 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.0 0.5 GO:0000281 mitotic cytokinesis(GO:0000281)
0.0 0.6 GO:0044042 glycogen metabolic process(GO:0005977) cellular glucan metabolic process(GO:0006073) glucan metabolic process(GO:0044042)
0.0 0.1 GO:1904103 regulation of convergent extension involved in gastrulation(GO:1904103)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.4 GO:0097134 cyclin E1-CDK2 complex(GO:0097134)
0.3 1.0 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.2 0.8 GO:0070319 Golgi to plasma membrane transport vesicle(GO:0070319)
0.1 1.2 GO:0032021 NELF complex(GO:0032021)
0.1 0.5 GO:0036396 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.1 0.5 GO:0097268 cytoophidium(GO:0097268)
0.1 0.8 GO:0032783 ELL-EAF complex(GO:0032783)
0.1 2.5 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.1 0.8 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.1 0.3 GO:0070545 PeBoW complex(GO:0070545)
0.1 0.8 GO:0005779 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.1 0.3 GO:1990745 EARP complex(GO:1990745)
0.1 0.4 GO:0070209 ASTRA complex(GO:0070209)
0.1 1.0 GO:0097431 mitotic spindle pole(GO:0097431)
0.1 0.8 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.1 0.9 GO:0030126 COPI vesicle coat(GO:0030126)
0.1 1.3 GO:0005640 nuclear outer membrane(GO:0005640)
0.1 0.5 GO:0016586 RSC complex(GO:0016586)
0.1 1.2 GO:0030667 secretory granule membrane(GO:0030667)
0.0 0.3 GO:1902636 kinociliary basal body(GO:1902636)
0.0 0.2 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.2 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.0 0.5 GO:0000109 nucleotide-excision repair complex(GO:0000109)
0.0 0.1 GO:0043202 vacuolar lumen(GO:0005775) lysosomal lumen(GO:0043202)
0.0 0.8 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 0.8 GO:0070822 Sin3-type complex(GO:0070822)
0.0 0.8 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 1.6 GO:0005657 replication fork(GO:0005657)
0.0 0.8 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.9 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 1.9 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.6 GO:0045335 phagocytic vesicle(GO:0045335)
0.0 1.3 GO:0031901 early endosome membrane(GO:0031901)
0.0 1.0 GO:0005758 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.0 0.9 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.1 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.1 GO:0071065 alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065)
0.0 2.6 GO:0070160 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 1.5 GO:0000922 spindle pole(GO:0000922)
0.0 0.2 GO:0001772 immunological synapse(GO:0001772)
0.0 0.1 GO:0005673 transcription factor TFIIE complex(GO:0005673)
0.0 0.6 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.5 GO:0005844 polysome(GO:0005844)
0.0 0.6 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 1.0 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 1.3 GO:0005769 early endosome(GO:0005769)
0.0 0.3 GO:0015030 Cajal body(GO:0015030)
0.0 0.6 GO:0030496 midbody(GO:0030496)
0.0 0.1 GO:0032433 filopodium tip(GO:0032433)
0.0 0.4 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.1 GO:0016600 flotillin complex(GO:0016600)
0.0 1.1 GO:0005871 kinesin complex(GO:0005871)
0.0 1.4 GO:0005882 intermediate filament(GO:0005882)
0.0 0.8 GO:0042383 sarcolemma(GO:0042383)
0.0 0.2 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.5 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.7 GO:0032592 integral component of mitochondrial membrane(GO:0032592)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.1 GO:0045174 glutathione dehydrogenase (ascorbate) activity(GO:0045174)
0.7 2.0 GO:0043878 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity(GO:0043878)
0.5 2.2 GO:0004361 glutaryl-CoA dehydrogenase activity(GO:0004361)
0.5 2.1 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.4 1.1 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.4 1.1 GO:0008517 folic acid transporter activity(GO:0008517)
0.3 1.6 GO:0043139 5'-3' DNA helicase activity(GO:0043139)
0.3 0.8 GO:0072591 N-acetyl-L-aspartate-L-glutamate ligase activity(GO:0072590) citrate-L-glutamate ligase activity(GO:0072591)
0.3 0.8 GO:0003868 4-hydroxyphenylpyruvate dioxygenase activity(GO:0003868)
0.3 1.0 GO:0004478 methionine adenosyltransferase activity(GO:0004478)
0.2 1.0 GO:0003958 NADPH-hemoprotein reductase activity(GO:0003958)
0.2 0.9 GO:0035516 oxidative DNA demethylase activity(GO:0035516)
0.2 1.1 GO:0004001 adenosine kinase activity(GO:0004001)
0.2 1.5 GO:1904047 S-adenosyl-L-methionine binding(GO:1904047)
0.2 0.6 GO:0003913 DNA photolyase activity(GO:0003913)
0.2 0.6 GO:0045145 single-stranded DNA 5'-3' exodeoxyribonuclease activity(GO:0045145)
0.2 1.2 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.2 1.0 GO:0016531 copper chaperone activity(GO:0016531)
0.2 1.5 GO:0008174 mRNA methyltransferase activity(GO:0008174)
0.2 1.3 GO:0016880 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.2 1.6 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.2 0.9 GO:1990757 anaphase-promoting complex binding(GO:0010997) ubiquitin ligase activator activity(GO:1990757)
0.2 1.1 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.1 0.5 GO:0003883 CTP synthase activity(GO:0003883)
0.1 1.0 GO:0050072 m7G(5')pppN diphosphatase activity(GO:0050072)
0.1 1.1 GO:0004586 ornithine decarboxylase activity(GO:0004586)
0.1 0.9 GO:0015232 heme transporter activity(GO:0015232)
0.1 1.0 GO:0005042 netrin receptor activity(GO:0005042)
0.1 1.0 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.1 0.4 GO:0015140 thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131) malate transmembrane transporter activity(GO:0015140)
0.1 0.4 GO:0004122 cystathionine beta-synthase activity(GO:0004122)
0.1 0.4 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.1 0.6 GO:0072518 Rho-dependent protein serine/threonine kinase activity(GO:0072518)
0.1 1.3 GO:0050811 GABA receptor binding(GO:0050811)
0.1 1.0 GO:0030544 Hsp70 protein binding(GO:0030544)
0.1 0.5 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.1 0.2 GO:0070224 sulfide:quinone oxidoreductase activity(GO:0070224)
0.1 0.8 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.1 0.7 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812)
0.1 0.8 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 0.4 GO:0034338 short-chain carboxylesterase activity(GO:0034338)
0.1 1.1 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.1 3.4 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.1 0.3 GO:0035613 RNA stem-loop binding(GO:0035613)
0.0 0.3 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.0 0.8 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.4 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0 0.5 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656)
0.0 1.8 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 0.3 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.0 0.1 GO:0033897 ribonuclease T2 activity(GO:0033897)
0.0 0.5 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
0.0 2.1 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.6 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.3 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.0 0.4 GO:0005522 profilin binding(GO:0005522)
0.0 0.7 GO:0070566 adenylyltransferase activity(GO:0070566)
0.0 2.5 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.7 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.2 GO:0034057 RNA strand annealing activity(GO:0033592) RNA strand-exchange activity(GO:0034057)
0.0 0.3 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.0 0.3 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 1.0 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.2 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.0 1.1 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 0.8 GO:0016307 phosphatidylinositol phosphate kinase activity(GO:0016307)
0.0 0.5 GO:0008649 rRNA methyltransferase activity(GO:0008649)
0.0 1.1 GO:0008175 tRNA methyltransferase activity(GO:0008175)
0.0 0.2 GO:0019865 IgE binding(GO:0019863) immunoglobulin binding(GO:0019865)
0.0 0.4 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.1 GO:0008489 UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity(GO:0008489)
0.0 0.7 GO:0051087 chaperone binding(GO:0051087)
0.0 0.4 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.6 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.2 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316)
0.0 0.1 GO:0000104 succinate dehydrogenase activity(GO:0000104)
0.0 0.1 GO:0001605 adrenomedullin receptor activity(GO:0001605) calcitonin gene-related peptide receptor activity(GO:0001635)
0.0 1.6 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 0.5 GO:0016876 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.0 0.7 GO:0003951 NAD+ kinase activity(GO:0003951)
0.0 1.3 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.2 GO:0048039 ubiquinone binding(GO:0048039)
0.0 0.3 GO:0004017 adenylate kinase activity(GO:0004017)
0.0 0.2 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.0 0.4 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.0 0.2 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.6 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.4 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.3 GO:0019211 phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542)
0.0 0.9 GO:0009055 electron carrier activity(GO:0009055)
0.0 0.2 GO:0008173 RNA methyltransferase activity(GO:0008173)
0.0 0.1 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.6 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 0.3 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 1.7 GO:0042803 protein homodimerization activity(GO:0042803)
0.0 0.3 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.0 0.2 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 1.0 GO:0016278 lysine N-methyltransferase activity(GO:0016278) protein-lysine N-methyltransferase activity(GO:0016279)
0.0 0.6 GO:0005347 ATP transmembrane transporter activity(GO:0005347)
0.0 0.2 GO:0051393 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.0 0.1 GO:0004126 cytidine deaminase activity(GO:0004126)
0.0 0.5 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 0.2 GO:0005123 death receptor binding(GO:0005123)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.2 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 0.6 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.1 1.3 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 1.2 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 1.0 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 2.7 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 0.7 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 0.6 PID BARD1 PATHWAY BARD1 signaling events
0.0 0.8 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 1.9 PID P73PATHWAY p73 transcription factor network
0.0 1.0 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.7 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 0.3 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.3 PID IL1 PATHWAY IL1-mediated signaling events
0.0 0.2 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.8 PID CMYB PATHWAY C-MYB transcription factor network
0.0 0.5 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.4 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.1 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.3 1.1 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.3 3.6 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.2 1.2 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.1 3.4 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.1 1.1 REACTOME EARLY PHASE OF HIV LIFE CYCLE Genes involved in Early Phase of HIV Life Cycle
0.1 1.0 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.1 1.1 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.1 0.5 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.1 0.7 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.1 0.6 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.4 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 0.8 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.0 0.9 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.5 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.5 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.7 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.4 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.7 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 0.4 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.5 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.0 0.3 REACTOME REGULATORY RNA PATHWAYS Genes involved in Regulatory RNA pathways
0.0 0.8 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.3 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 1.1 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 1.3 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 2.1 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.8 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.2 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.9 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.5 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.2 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.3 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.2 REACTOME FATTY ACYL COA BIOSYNTHESIS Genes involved in Fatty Acyl-CoA Biosynthesis
0.0 0.1 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 0.5 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK