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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for SPDEF

Z-value: 1.24

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Transcription factors associated with SPDEF

Gene Symbol Gene ID Gene Info
SPDEF
ENSDARG00000029930 SAM pointed domain containing ETS transcription factor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SPDEFdr11_v1_chr6_-_54290227_54290227-0.726.8e-04Click!

Activity profile of SPDEF motif

Sorted Z-values of SPDEF motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr3_-_3398383 4.39 ENSDART00000047865
si:dkey-46g23.2
si:dkey-46g23.2
chr3_-_3413669 4.08 ENSDART00000113517
ENSDART00000179861
ENSDART00000115331
zgc:171446
zgc:171446
chr22_-_5171362 3.15 ENSDART00000124889
tnfaip8l1
tumor necrosis factor, alpha-induced protein 8-like 1
chr21_-_43636595 3.12 ENSDART00000151115
ENSDART00000151486
ENSDART00000151778
si:ch1073-263o8.2
si:ch1073-263o8.2
chr15_+_38299385 2.97 ENSDART00000142403
si:dkey-24p1.6
si:dkey-24p1.6
chr15_+_38299563 2.82 ENSDART00000099375
si:dkey-24p1.6
si:dkey-24p1.6
chr25_+_8921425 2.68 ENSDART00000128591
accs
1-aminocyclopropane-1-carboxylate synthase homolog (Arabidopsis)(non-functional)
chr20_-_23254876 2.65 ENSDART00000141510
ociad1
OCIA domain containing 1
chr21_-_30994577 2.42 ENSDART00000065503
pgap2
post-GPI attachment to proteins 2
chr3_-_36440705 2.39 ENSDART00000162875
rogdi
rogdi homolog (Drosophila)
chr24_+_15020402 2.39 ENSDART00000148102
dok6
docking protein 6
chr5_+_44806374 2.38 ENSDART00000184237
ctsla
cathepsin La
chr2_+_32846602 2.35 ENSDART00000056649
tmem53
transmembrane protein 53
chr20_+_13141408 2.34 ENSDART00000034098
dtl
denticleless E3 ubiquitin protein ligase homolog (Drosophila)
chr2_+_51818039 2.30 ENSDART00000170353
acvr2bb
activin A receptor type 2Bb
chr8_+_17143501 2.16 ENSDART00000061758
mier3b
mesoderm induction early response 1, family member 3 b
chr24_-_32522587 2.12 ENSDART00000048968
ENSDART00000143781
EIF1B
zgc:56676
chr20_-_23253630 2.11 ENSDART00000103365
ociad1
OCIA domain containing 1
chr20_+_27087539 2.09 ENSDART00000062094
tmem251
transmembrane protein 251
chr2_+_30182431 2.05 ENSDART00000004903
rdh10b
retinol dehydrogenase 10b
chr15_+_46313082 2.03 ENSDART00000153830
si:ch1073-190k2.1
si:ch1073-190k2.1
chr6_+_3334392 1.93 ENSDART00000133707
ENSDART00000130879
st3gal3a
ST3 beta-galactoside alpha-2,3-sialyltransferase 3a
chr8_-_1267247 1.92 ENSDART00000150064
cdc14b
cell division cycle 14B
chr20_-_10487951 1.90 ENSDART00000064112
glrx5
glutaredoxin 5 homolog (S. cerevisiae)
chr20_-_48898560 1.89 ENSDART00000163071
xrn2
5'-3' exoribonuclease 2
chr5_+_6854345 1.87 ENSDART00000066307
elac1
elaC ribonuclease Z 1
chr20_-_48898371 1.87 ENSDART00000170617
xrn2
5'-3' exoribonuclease 2
chr3_-_34136368 1.85 ENSDART00000136900
ENSDART00000186125
clpp
caseinolytic mitochondrial matrix peptidase proteolytic subunit
chr5_+_6854498 1.81 ENSDART00000148663
elac1
elaC ribonuclease Z 1
chr5_+_47863153 1.78 ENSDART00000051518
rasa1a
RAS p21 protein activator (GTPase activating protein) 1a
chr15_-_2519640 1.78 ENSDART00000047013
srprb
signal recognition particle receptor, B subunit
chr8_+_47683352 1.77 ENSDART00000187320
ENSDART00000192605
dpp9
dipeptidyl-peptidase 9
chr8_+_47683539 1.76 ENSDART00000190701
dpp9
dipeptidyl-peptidase 9
chr12_-_31724198 1.76 ENSDART00000153056
ENSDART00000165299
ENSDART00000137464
ENSDART00000080173
srsf2a
serine/arginine-rich splicing factor 2a
chr15_+_34933552 1.74 ENSDART00000155368
zgc:66024
zgc:66024
chr7_+_35191220 1.69 ENSDART00000110552
zdhhc1
zinc finger, DHHC-type containing 1
chr13_+_9559461 1.67 ENSDART00000047740
wdr32
WD repeat domain 32
chr23_+_4260458 1.66 ENSDART00000103747
srsf6a
serine/arginine-rich splicing factor 6a
chr14_-_5407555 1.65 ENSDART00000001424
pcgf1
polycomb group ring finger 1
chr8_+_48965767 1.61 ENSDART00000008058
aak1a
AP2 associated kinase 1a
chr9_-_28255029 1.59 ENSDART00000160387
ccnyl1
cyclin Y-like 1
chr5_-_52010122 1.59 ENSDART00000073627
ENSDART00000163898
ENSDART00000051003
cdk7
cyclin-dependent kinase 7
chr8_+_48966165 1.57 ENSDART00000165425
aak1a
AP2 associated kinase 1a
chr8_-_1266181 1.57 ENSDART00000148654
ENSDART00000149924
cdc14b
cell division cycle 14B
chr1_-_23294753 1.54 ENSDART00000013263
ugdh
UDP-glucose 6-dehydrogenase
chr3_-_34136778 1.54 ENSDART00000131951
clpp
caseinolytic mitochondrial matrix peptidase proteolytic subunit
chr5_+_41477954 1.54 ENSDART00000185871
pias2
protein inhibitor of activated STAT, 2
chr2_+_2772447 1.53 ENSDART00000124882
thoc1
THO complex 1
chr14_-_5407118 1.50 ENSDART00000168074
pcgf1
polycomb group ring finger 1
chr9_+_14023386 1.48 ENSDART00000140199
ENSDART00000124267
si:ch211-67e16.4
si:ch211-67e16.4
chr3_+_19665319 1.47 ENSDART00000007857
ENSDART00000193509
mettl2a
methyltransferase like 2A
chr21_+_38033226 1.45 ENSDART00000085728
klf8
Kruppel-like factor 8
chr1_+_49435017 1.44 ENSDART00000124833
pdcd11
programmed cell death 11
chr15_-_41311292 1.44 ENSDART00000133835
ENSDART00000085645
ENSDART00000134075
usp16
ubiquitin specific peptidase 16
chr9_-_41090048 1.43 ENSDART00000131681
ENSDART00000182552
asnsd1
asparagine synthetase domain containing 1
chr9_-_21238159 1.42 ENSDART00000146764
ENSDART00000102143
cox17
COX17 cytochrome c oxidase copper chaperone
chr1_-_40519340 1.39 ENSDART00000114659
maml3
mastermind-like transcriptional coactivator 3
chr1_-_28950366 1.38 ENSDART00000110270
pwp2h
PWP2 periodic tryptophan protein homolog (yeast)
chr13_-_33654931 1.35 ENSDART00000020350
snx5
sorting nexin 5
chr7_+_38809241 1.34 ENSDART00000190979
harbi1
harbinger transposase derived 1
chr18_+_6638726 1.34 ENSDART00000142755
ENSDART00000167781
c2cd5
C2 calcium-dependent domain containing 5
chr10_+_43037064 1.32 ENSDART00000160159
atg10
ATG10 autophagy related 10 homolog (S. cerevisiae)
chr18_+_3169579 1.32 ENSDART00000164724
ENSDART00000186340
ENSDART00000181247
ENSDART00000168056
pak1
p21 protein (Cdc42/Rac)-activated kinase 1
chr5_+_25084385 1.32 ENSDART00000134526
ENSDART00000111863
paxx
PAXX, non-homologous end joining factor
chr3_+_36617024 1.31 ENSDART00000189957
pdxdc1
pyridoxal-dependent decarboxylase domain containing 1
chr15_+_25528290 1.30 ENSDART00000123143
npat
nuclear protein, ataxia-telangiectasia locus
chr17_-_7351488 1.30 ENSDART00000098731
stxbp5b
syntaxin binding protein 5b (tomosyn)
chr5_-_32489796 1.29 ENSDART00000168870
gpr107
G protein-coupled receptor 107
chr22_-_10752471 1.29 ENSDART00000081191
sass6
SAS-6 centriolar assembly protein
chr7_-_32629458 1.29 ENSDART00000001376
arl14ep
ADP-ribosylation factor-like 14 effector protein
chr22_-_5171829 1.29 ENSDART00000140313
tnfaip8l1
tumor necrosis factor, alpha-induced protein 8-like 1
chr3_-_34528306 1.29 ENSDART00000023039
sept9a
septin 9a
chr18_+_6638974 1.28 ENSDART00000162398
c2cd5
C2 calcium-dependent domain containing 5
chr5_+_51833305 1.27 ENSDART00000165276
ENSDART00000166443
papd4
PAP associated domain containing 4
chr6_+_46406565 1.26 ENSDART00000168440
ENSDART00000131203
ENSDART00000138567
ENSDART00000132845
pbrm1l
polybromo 1, like
chr19_-_34742440 1.24 ENSDART00000122625
ENSDART00000175621
elp2
elongator acetyltransferase complex subunit 2
chr5_-_26795438 1.24 ENSDART00000146124
si:ch211-102c2.7
si:ch211-102c2.7
chr5_-_23596339 1.24 ENSDART00000024815
fam76b
family with sequence similarity 76, member B
chr13_+_24022963 1.22 ENSDART00000028285
pgbd5
piggyBac transposable element derived 5
chr14_-_45558490 1.20 ENSDART00000165060
ints5
integrator complex subunit 5
chr15_+_17343319 1.20 ENSDART00000018461
vmp1
vacuole membrane protein 1
chr1_+_12335816 1.20 ENSDART00000067086
nansa
N-acetylneuraminic acid synthase a
chr9_+_25853052 1.19 ENSDART00000127135
gtdc1
glycosyltransferase-like domain containing 1
chr13_+_31545530 1.18 ENSDART00000164590
ENSDART00000178460
ENSDART00000185503
ppm1aa
protein phosphatase, Mg2+/Mn2+ dependent, 1Aa
chr3_+_25166805 1.15 ENSDART00000077493
TST
zgc:162544
chr13_+_31545812 1.14 ENSDART00000076527
ppm1aa
protein phosphatase, Mg2+/Mn2+ dependent, 1Aa
chr19_+_34230108 1.14 ENSDART00000141950
galnt12
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 12
chr17_+_39790388 1.14 ENSDART00000149488
ubr1
ubiquitin protein ligase E3 component n-recognin 1
chr1_+_41596099 1.12 ENSDART00000111367
si:dkey-56e3.3
si:dkey-56e3.3
chr24_+_19522094 1.10 ENSDART00000191042
ENSDART00000184714
ENSDART00000180782
sulf1
sulfatase 1
chr15_-_34878388 1.10 ENSDART00000154094
mgat1a
mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase a
chr5_-_13086616 1.09 ENSDART00000051664
ypel1
yippee-like 1
chr20_-_39789036 1.08 ENSDART00000086405
ENSDART00000098253
rnf217
ring finger protein 217
chr14_-_23684814 1.07 ENSDART00000024604
mars2
methionyl-tRNA synthetase 2, mitochondrial
chr16_+_32184485 1.06 ENSDART00000084009
zufsp
zinc finger with UFM1-specific peptidase domain
chr10_+_15970 1.06 ENSDART00000040240
tiprl
TIP41, TOR signaling pathway regulator-like (S. cerevisiae)
chr13_-_33700461 1.04 ENSDART00000160520
mad2l1bp
MAD2L1 binding protein
chr11_+_25693395 1.03 ENSDART00000110224
mon1bb
MON1 secretory trafficking family member Bb
chr4_-_287425 1.00 ENSDART00000159128
echdc3
enoyl CoA hydratase domain containing 3
chr4_+_13931578 0.99 ENSDART00000142466
pphln1
periphilin 1
chr5_-_23117078 0.98 ENSDART00000051529
uprt
uracil phosphoribosyltransferase (FUR1) homolog (S. cerevisiae)
chr7_-_29356084 0.97 ENSDART00000075757
gtf2a2
general transcription factor IIA, 2
chr2_+_49457626 0.97 ENSDART00000129967
sh3gl1a
SH3-domain GRB2-like 1a
chr7_+_35193832 0.95 ENSDART00000189002
zdhhc1
zinc finger, DHHC-type containing 1
chr4_-_22749553 0.95 ENSDART00000040033
nup107
nucleoporin 107
chr17_+_37253706 0.95 ENSDART00000076004
tmem62
transmembrane protein 62
chr11_-_16975190 0.94 ENSDART00000122222
suclg2
succinate-CoA ligase, GDP-forming, beta subunit
chr25_-_3347418 0.91 ENSDART00000082385
golt1bb
golgi transport 1Bb
chr1_+_47165842 0.90 ENSDART00000053152
ENSDART00000167051
cbr1
carbonyl reductase 1
chr20_+_715739 0.90 ENSDART00000136768
myo6a
myosin VIa
chr2_+_16652238 0.90 ENSDART00000091351
gk5
glycerol kinase 5 (putative)
chr2_+_49457449 0.89 ENSDART00000185470
sh3gl1a
SH3-domain GRB2-like 1a
chr12_+_46543572 0.89 ENSDART00000167510
hid1b
HID1 domain containing b
chr17_+_33375469 0.88 ENSDART00000032827
zgc:162964
zgc:162964
chr3_-_3372259 0.87 ENSDART00000140482
si:dkey-46g23.1
si:dkey-46g23.1
chr5_+_51833132 0.87 ENSDART00000167491
papd4
PAP associated domain containing 4
chr12_-_9468618 0.87 ENSDART00000152737
ENSDART00000091519
pgap3
post-GPI attachment to proteins 3
chr5_+_44346691 0.87 ENSDART00000034523
tars
threonyl-tRNA synthetase
chr19_-_1871415 0.86 ENSDART00000004585
clptm1l
CLPTM1-like
chr6_+_12482599 0.86 ENSDART00000090316
stk24b
serine/threonine kinase 24b (STE20 homolog, yeast)
chr5_+_32490238 0.86 ENSDART00000191839
ndor1
NADPH dependent diflavin oxidoreductase 1
chr1_-_51720633 0.85 ENSDART00000045894
rnaseh2a
ribonuclease H2, subunit A
chr9_-_41090343 0.85 ENSDART00000187769
ENSDART00000180078
ENSDART00000166785
asnsd1
asparagine synthetase domain containing 1
chr10_+_36439293 0.84 ENSDART00000043802
uspl1
ubiquitin specific peptidase like 1
chr13_-_42673978 0.84 ENSDART00000133848
ENSDART00000099738
ENSDART00000099729
ENSDART00000169083
lrrfip2
leucine rich repeat (in FLII) interacting protein 2
chr24_+_31459715 0.83 ENSDART00000181102
ENSDART00000189950
ENSDART00000192321
ENSDART00000126380
cnbd1
cyclic nucleotide binding domain containing 1
chr6_+_4387150 0.83 ENSDART00000181283
rbm26
RNA binding motif protein 26
chr5_+_29715040 0.82 ENSDART00000192563
ddx31
DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
chr22_-_8306743 0.82 ENSDART00000123982
CABZ01077218.1

chr18_+_3634652 0.81 ENSDART00000159913
lrch3
leucine-rich repeats and calponin homology (CH) domain containing 3
chr8_+_30112655 0.81 ENSDART00000099027
fancc
Fanconi anemia, complementation group C
chr6_-_39080630 0.80 ENSDART00000021520
ENSDART00000128308
eif4bb
eukaryotic translation initiation factor 4Bb
chr17_-_27382826 0.79 ENSDART00000186657
ENSDART00000155986
ENSDART00000191060
ENSDART00000077608
si:ch1073-358c10.1
si:ch1073-358c10.1
chr17_+_8754020 0.79 ENSDART00000105322
edrf1
erythroid differentiation regulatory factor 1
chr4_-_20108833 0.79 ENSDART00000100867
fam3c
family with sequence similarity 3, member C
chr15_+_17100697 0.79 ENSDART00000183565
ENSDART00000123197
relb
v-rel avian reticuloendotheliosis viral oncogene homolog B
chr20_-_30938184 0.78 ENSDART00000147359
ENSDART00000062552
wtap
WT1 associated protein
chr16_-_44673851 0.77 ENSDART00000015139
dcaf13
ddb1 and cul4 associated factor 13
chr14_-_30876299 0.77 ENSDART00000180305
ubl3b
ubiquitin-like 3b
chr3_-_36419641 0.77 ENSDART00000173545
cog1
component of oligomeric golgi complex 1
chr12_+_29240124 0.76 ENSDART00000053761
ENSDART00000130172
bms1
BMS1 ribosome biogenesis factor
chr1_-_44581937 0.76 ENSDART00000009858
tmx2b
thioredoxin-related transmembrane protein 2b
chr3_-_24681404 0.75 ENSDART00000161612
BX569789.1

chr22_+_8753092 0.75 ENSDART00000140720
si:dkey-182g1.2
si:dkey-182g1.2
chr22_+_8753365 0.75 ENSDART00000106086
si:dkey-182g1.2
si:dkey-182g1.2
chr8_-_17184482 0.75 ENSDART00000025803
pola2
polymerase (DNA directed), alpha 2
chr6_-_54444929 0.74 ENSDART00000154121
sys1
Sys1 golgi trafficking protein
chr5_-_55933420 0.73 ENSDART00000050966
slc25a46
solute carrier family 25, member 46
chr15_-_25365319 0.73 ENSDART00000152651
cluha
clustered mitochondria (cluA/CLU1) homolog a
chr2_+_16798652 0.73 ENSDART00000145778
ENSDART00000087120
eif4g1a
eukaryotic translation initiation factor 4 gamma, 1a
chr19_-_43004356 0.73 ENSDART00000098101
zcchc17
zinc finger, CCHC domain containing 17
chr16_+_12812214 0.72 ENSDART00000124875
u2af2a
U2 small nuclear RNA auxiliary factor 2a
chr19_+_6904314 0.72 ENSDART00000151502
si:ch1073-127d16.1
si:ch1073-127d16.1
chr17_+_49281597 0.71 ENSDART00000155599
zgc:113176
zgc:113176
chr15_-_43625549 0.71 ENSDART00000168589
ctsc
cathepsin C
chr6_-_54433995 0.69 ENSDART00000017230
snrpc
small nuclear ribonucleoprotein polypeptide C
chr1_-_44048798 0.69 ENSDART00000073746
si:ch73-109d9.2
si:ch73-109d9.2
chr1_+_24557414 0.68 ENSDART00000076519
dctpp1
dCTP pyrophosphatase 1
chr16_-_17345377 0.68 ENSDART00000143056
zyx
zyxin
chr20_-_1191910 0.67 ENSDART00000043218
ube2j1
ubiquitin-conjugating enzyme E2, J1
chr6_+_3334710 0.66 ENSDART00000132848
st3gal3a
ST3 beta-galactoside alpha-2,3-sialyltransferase 3a
chr7_-_36358303 0.66 ENSDART00000130028
fto
fat mass and obesity associated
chr6_-_18531760 0.66 ENSDART00000167167
utp6
UTP6, small subunit (SSU) processome component, homolog (yeast)
chr12_-_14211293 0.65 ENSDART00000158399
avl9
AVL9 homolog (S. cerevisiase)
chr5_+_29714786 0.65 ENSDART00000148314
ddx31
DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
chr8_+_39770162 0.64 ENSDART00000190677
hps4
Hermansky-Pudlak syndrome 4
chr12_-_14211067 0.64 ENSDART00000077903
avl9
AVL9 homolog (S. cerevisiase)
chr7_-_36358735 0.64 ENSDART00000188392
fto
fat mass and obesity associated
chr4_-_12978925 0.64 ENSDART00000013839
tmbim4
transmembrane BAX inhibitor motif containing 4
chr22_-_5663354 0.63 ENSDART00000081774
ccdc51
coiled-coil domain containing 51
chr11_-_28050559 0.63 ENSDART00000136859
ece1
endothelin converting enzyme 1
chr13_+_14006118 0.63 ENSDART00000131875
ENSDART00000089528
atrn
attractin
chr4_+_13931733 0.62 ENSDART00000141742
ENSDART00000067175
pphln1
periphilin 1
chr17_+_24684778 0.62 ENSDART00000146309
ENSDART00000082237
znf593
zinc finger protein 593
chr15_-_25365570 0.61 ENSDART00000152754
cluha
clustered mitochondria (cluA/CLU1) homolog a
chr19_+_9212031 0.61 ENSDART00000052930
ndufv1
NADH dehydrogenase (ubiquinone) flavoprotein 1
chr24_-_7826489 0.61 ENSDART00000112777
si:dkey-197c15.6
si:dkey-197c15.6
chr24_+_37533728 0.61 ENSDART00000061203
rhot2
ras homolog family member T2
chr2_-_20052561 0.61 ENSDART00000100133
dpydb
dihydropyrimidine dehydrogenase b
chr19_-_19025998 0.60 ENSDART00000186156
ENSDART00000163359
ENSDART00000167951
dync1li1
dynein, cytoplasmic 1, light intermediate chain 1
chr18_-_18584839 0.60 ENSDART00000159274
sf3b3
splicing factor 3b, subunit 3
chr14_-_33521071 0.60 ENSDART00000052789
c1galt1c1
C1GALT1-specific chaperone 1
chr1_-_55008882 0.58 ENSDART00000083572
zgc:136864
zgc:136864
chr2_-_42173834 0.58 ENSDART00000098357
ENSDART00000144707
slc39a6
solute carrier family 39 (zinc transporter), member 6
chr3_-_40276057 0.58 ENSDART00000132225
ENSDART00000074737
shmt1
serine hydroxymethyltransferase 1 (soluble)
chr18_-_26797723 0.57 ENSDART00000008013
sec11a
SEC11 homolog A, signal peptidase complex subunit
chr25_-_10791437 0.54 ENSDART00000127054
BX572619.1

chr9_-_23824290 0.54 ENSDART00000059209
wdfy2
WD repeat and FYVE domain containing 2
chr7_-_71384391 0.54 ENSDART00000112841
ccdc149a
coiled-coil domain containing 149a
chr4_+_15605844 0.54 ENSDART00000101619
ENSDART00000021384
exoc4
exocyst complex component 4
chr5_+_42064144 0.54 ENSDART00000035235
si:ch211-202a12.4
si:ch211-202a12.4
chr25_+_22853718 0.54 ENSDART00000073588
kcnj11
potassium inwardly-rectifying channel, subfamily J, member 11
chr19_+_43004408 0.53 ENSDART00000038230
snrnp40
small nuclear ribonucleoprotein 40 (U5)
chr11_+_44236183 0.53 ENSDART00000193470
gnb4b
guanine nucleotide binding protein (G protein), beta polypeptide 4b
chr19_-_17658160 0.53 ENSDART00000151766
ENSDART00000170790
ENSDART00000186678
ENSDART00000188045
ENSDART00000176980
ENSDART00000166313
ENSDART00000188589
thrb
thyroid hormone receptor beta
chr9_-_24218367 0.53 ENSDART00000135356
nabp1a
nucleic acid binding protein 1a
chr5_-_26893310 0.53 ENSDART00000126669
lman2lb
lectin, mannose-binding 2-like b
chr6_-_18531349 0.52 ENSDART00000160693
ENSDART00000169780
utp6
UTP6, small subunit (SSU) processome component, homolog (yeast)
chr19_+_9455218 0.52 ENSDART00000139385
si:ch211-288g17.3
si:ch211-288g17.3
chr15_-_15230264 0.52 ENSDART00000155400
rrp8
ribosomal RNA processing 8, methyltransferase, homolog (yeast)

Network of associatons between targets according to the STRING database.

First level regulatory network of SPDEF

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 3.7 GO:0042779 tRNA 3'-trailer cleavage(GO:0042779)
0.6 2.3 GO:0006529 asparagine biosynthetic process(GO:0006529)
0.5 2.6 GO:0010828 positive regulation of glucose transport(GO:0010828)
0.5 1.4 GO:0070537 histone H2A K63-linked deubiquitination(GO:0070537)
0.4 1.3 GO:0042245 RNA repair(GO:0042245)
0.4 2.3 GO:0072422 signal transduction involved in DNA integrity checkpoint(GO:0072401) signal transduction involved in DNA damage checkpoint(GO:0072422) signal transduction involved in G2 DNA damage checkpoint(GO:0072425)
0.3 3.5 GO:0071850 mitotic cell cycle arrest(GO:0071850)
0.3 1.6 GO:0097355 protein localization to heterochromatin(GO:0097355)
0.3 1.6 GO:1904031 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.3 0.9 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.3 1.4 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.2 0.7 GO:0009211 pyrimidine deoxyribonucleoside triphosphate metabolic process(GO:0009211)
0.2 1.1 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.2 3.2 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.2 1.5 GO:0003190 heart valve formation(GO:0003188) atrioventricular valve formation(GO:0003190)
0.2 1.3 GO:0003232 bulbus arteriosus development(GO:0003232)
0.2 0.6 GO:0046125 deoxyribonucleoside metabolic process(GO:0009120) thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.2 0.6 GO:0019264 glycine biosynthetic process from serine(GO:0019264)
0.2 3.2 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747) regulation of clathrin-mediated endocytosis(GO:2000369)
0.2 1.3 GO:0040016 embryonic cleavage(GO:0040016)
0.2 0.8 GO:1904867 nuclear body organization(GO:0030575) Cajal body organization(GO:0030576) protein localization to nuclear body(GO:1903405) protein localization to Cajal body(GO:1904867) protein localization to nucleoplasm(GO:1990173)
0.2 0.5 GO:0010847 regulation of chromatin assembly(GO:0010847)
0.2 0.6 GO:1903232 melanosome assembly(GO:1903232)
0.2 2.1 GO:0042572 retinol metabolic process(GO:0042572)
0.2 0.6 GO:0016267 O-glycan processing, core 1(GO:0016267)
0.1 0.9 GO:0019563 glycerol catabolic process(GO:0019563)
0.1 0.4 GO:0008344 adult locomotory behavior(GO:0008344)
0.1 1.3 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.1 0.9 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.1 1.1 GO:0021910 smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021910) regulation of myotome development(GO:2000290)
0.1 0.4 GO:1990120 messenger ribonucleoprotein complex assembly(GO:1990120)
0.1 0.5 GO:0046552 retinal cone cell fate determination(GO:0042671) eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate determination(GO:0043703) retinal cone cell fate commitment(GO:0046551) photoreceptor cell fate commitment(GO:0046552) camera-type eye photoreceptor cell fate commitment(GO:0060220)
0.1 2.8 GO:0031163 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.1 0.8 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.1 1.4 GO:0021707 cerebellar granular layer development(GO:0021681) cerebellar granular layer morphogenesis(GO:0021683) cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.1 0.8 GO:0080009 mRNA methylation(GO:0080009)
0.1 0.8 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.1 4.1 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.1 3.4 GO:0006515 misfolded or incompletely synthesized protein catabolic process(GO:0006515)
0.1 0.6 GO:0045448 regulation of mitotic cell cycle, embryonic(GO:0009794) mitotic cell cycle, embryonic(GO:0045448)
0.1 0.7 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.1 0.3 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.1 0.8 GO:0097010 eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.1 1.3 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.1 1.2 GO:0032196 transposition(GO:0032196)
0.1 0.3 GO:0060043 regulation of cardiac muscle tissue growth(GO:0055021) regulation of cardiac muscle cell proliferation(GO:0060043)
0.1 1.2 GO:0044872 lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
0.1 1.6 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.1 0.5 GO:0030328 prenylated protein catabolic process(GO:0030327) prenylcysteine catabolic process(GO:0030328) prenylcysteine metabolic process(GO:0030329)
0.1 0.6 GO:0006465 signal peptide processing(GO:0006465)
0.1 0.7 GO:0006895 Golgi to endosome transport(GO:0006895)
0.1 4.1 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.1 0.4 GO:0090202 transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
0.1 0.5 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.1 0.3 GO:2000622 negative regulation of mRNA catabolic process(GO:1902373) regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.1 3.0 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.1 0.9 GO:0035479 angioblast cell migration from lateral mesoderm to midline(GO:0035479)
0.1 1.4 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617) response to copper ion(GO:0046688) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.1 1.8 GO:0072599 protein targeting to ER(GO:0045047) establishment of protein localization to endoplasmic reticulum(GO:0072599)
0.1 0.6 GO:0097345 mitochondrial outer membrane permeabilization(GO:0097345)
0.1 7.7 GO:0010466 negative regulation of peptidase activity(GO:0010466)
0.1 0.6 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.1 0.6 GO:0007096 regulation of exit from mitosis(GO:0007096)
0.1 1.8 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.1 0.6 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.1 0.1 GO:0061011 hepatic duct development(GO:0061011)
0.1 1.1 GO:0046660 female sex differentiation(GO:0046660)
0.1 0.9 GO:0035278 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.1 1.2 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.1 0.1 GO:0043504 mitochondrial DNA repair(GO:0043504)
0.1 1.5 GO:0016925 protein sumoylation(GO:0016925)
0.1 0.3 GO:0051972 regulation of telomerase activity(GO:0051972)
0.1 1.5 GO:0006303 double-strand break repair via nonhomologous end joining(GO:0006303)
0.1 0.5 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.0 0.1 GO:0015824 L-alanine transport(GO:0015808) proline transport(GO:0015824)
0.0 0.4 GO:0007220 Notch receptor processing(GO:0007220)
0.0 1.6 GO:0016180 snRNA processing(GO:0016180)
0.0 0.8 GO:0035196 production of miRNAs involved in gene silencing by miRNA(GO:0035196)
0.0 1.5 GO:0071427 mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.0 1.1 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0 1.2 GO:0038061 NIK/NF-kappaB signaling(GO:0038061)
0.0 0.6 GO:0016486 peptide hormone processing(GO:0016486)
0.0 1.0 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
0.0 0.8 GO:0008156 negative regulation of DNA replication(GO:0008156)
0.0 0.5 GO:0044818 mitotic G2/M transition checkpoint(GO:0044818)
0.0 0.5 GO:0006903 vesicle targeting(GO:0006903)
0.0 1.3 GO:0050708 regulation of protein secretion(GO:0050708)
0.0 1.3 GO:0046466 sphingolipid catabolic process(GO:0030149) membrane lipid catabolic process(GO:0046466)
0.0 0.5 GO:0031060 regulation of histone methylation(GO:0031060)
0.0 0.4 GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625)
0.0 1.4 GO:0032924 activin receptor signaling pathway(GO:0032924)
0.0 0.7 GO:0090148 membrane fission(GO:0090148)
0.0 0.7 GO:0043489 RNA stabilization(GO:0043489)
0.0 0.8 GO:0036297 interstrand cross-link repair(GO:0036297)
0.0 0.8 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.7 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0 0.2 GO:0016074 snoRNA metabolic process(GO:0016074)
0.0 0.2 GO:0046620 regulation of organ growth(GO:0046620)
0.0 0.3 GO:0009303 rRNA transcription(GO:0009303)
0.0 0.1 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.0 1.0 GO:0006623 protein targeting to vacuole(GO:0006623)
0.0 0.4 GO:0016233 telomere capping(GO:0016233)
0.0 0.5 GO:0045841 mitotic spindle assembly checkpoint(GO:0007094) spindle checkpoint(GO:0031577) negative regulation of mitotic metaphase/anaphase transition(GO:0045841) spindle assembly checkpoint(GO:0071173) mitotic spindle checkpoint(GO:0071174)
0.0 1.3 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.0 0.5 GO:0003323 type B pancreatic cell development(GO:0003323)
0.0 0.4 GO:0006513 protein monoubiquitination(GO:0006513)
0.0 0.7 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.3 GO:0042026 protein refolding(GO:0042026)
0.0 1.3 GO:0072583 clathrin-mediated endocytosis(GO:0072583)
0.0 0.2 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 1.6 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.3 GO:0045116 protein neddylation(GO:0045116)
0.0 5.6 GO:0070085 glycosylation(GO:0070085)
0.0 1.4 GO:0000956 nuclear-transcribed mRNA catabolic process(GO:0000956)
0.0 0.2 GO:0051382 kinetochore assembly(GO:0051382)
0.0 1.4 GO:0008033 tRNA processing(GO:0008033)
0.0 0.6 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.0 0.4 GO:0035987 endodermal cell differentiation(GO:0035987)
0.0 0.9 GO:0007179 transforming growth factor beta receptor signaling pathway(GO:0007179) response to transforming growth factor beta(GO:0071559) cellular response to transforming growth factor beta stimulus(GO:0071560)
0.0 1.3 GO:0016236 macroautophagy(GO:0016236)
0.0 0.6 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.0 0.1 GO:0032732 positive regulation of interleukin-1 production(GO:0032732)
0.0 1.3 GO:0007219 Notch signaling pathway(GO:0007219)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.3 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.6 2.4 GO:0043291 RAVE complex(GO:0043291)
0.4 1.3 GO:0098536 deuterosome(GO:0098536)
0.4 2.6 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.3 0.9 GO:0042709 succinate-CoA ligase complex(GO:0042709)
0.2 1.0 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.2 1.5 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.2 0.9 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.2 0.8 GO:0045293 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.2 0.9 GO:0005797 Golgi medial cisterna(GO:0005797)
0.2 1.3 GO:0070419 nonhomologous end joining complex(GO:0070419)
0.2 0.6 GO:0031085 BLOC-3 complex(GO:0031085)
0.2 1.3 GO:0016586 RSC complex(GO:0016586)
0.2 0.8 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.1 1.6 GO:0005675 holo TFIIH complex(GO:0005675)
0.1 0.6 GO:0005787 signal peptidase complex(GO:0005787)
0.1 0.4 GO:0042382 paraspeckles(GO:0042382)
0.1 0.5 GO:0032584 growth cone membrane(GO:0032584)
0.1 3.2 GO:0035102 PRC1 complex(GO:0035102)
0.1 1.8 GO:0000243 commitment complex(GO:0000243)
0.1 1.2 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.1 0.5 GO:0033553 rDNA heterochromatin(GO:0033553)
0.1 1.4 GO:0048179 activin receptor complex(GO:0048179)
0.1 2.3 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.1 0.5 GO:0070876 SOSS complex(GO:0070876)
0.1 0.9 GO:0031080 nuclear pore outer ring(GO:0031080)
0.1 1.6 GO:0032039 integrator complex(GO:0032039)
0.1 0.8 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.1 2.2 GO:0032040 small-subunit processome(GO:0032040)
0.1 1.5 GO:0000784 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783) nuclear chromosome, telomeric region(GO:0000784)
0.1 0.6 GO:0071005 U2-type precatalytic spliceosome(GO:0071005)
0.1 0.7 GO:0005682 U5 snRNP(GO:0005682)
0.1 0.8 GO:0017119 Golgi transport complex(GO:0017119)
0.1 0.8 GO:0030686 90S preribosome(GO:0030686)
0.1 0.2 GO:0000931 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.1 0.8 GO:0015030 Cajal body(GO:0015030)
0.1 0.4 GO:0070765 gamma-secretase complex(GO:0070765)
0.0 3.4 GO:0072686 mitotic spindle(GO:0072686)
0.0 0.6 GO:0046540 U4/U6 x U5 tri-snRNP complex(GO:0046540)
0.0 1.1 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.6 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 1.3 GO:0032156 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0 0.1 GO:0031251 PAN complex(GO:0031251)
0.0 3.4 GO:0016607 nuclear speck(GO:0016607)
0.0 1.2 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 0.6 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 1.9 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.3 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.7 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.9 GO:0032587 ruffle membrane(GO:0032587)
0.0 1.9 GO:0005769 early endosome(GO:0005769)
0.0 0.9 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.8 GO:0005758 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.0 1.3 GO:0055037 recycling endosome(GO:0055037)
0.0 1.3 GO:0031201 SNARE complex(GO:0031201)
0.0 0.9 GO:0005811 lipid particle(GO:0005811)
0.0 1.3 GO:0030136 clathrin-coated vesicle(GO:0030136)
0.0 0.9 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.7 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 1.1 GO:0005795 Golgi stack(GO:0005795)
0.0 9.3 GO:0005794 Golgi apparatus(GO:0005794)
0.0 0.2 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.6 GO:0016592 mediator complex(GO:0016592)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.7 GO:0042781 3'-tRNA processing endoribonuclease activity(GO:0042781)
0.9 3.8 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.6 2.3 GO:0004066 asparagine synthase (glutamine-hydrolyzing) activity(GO:0004066)
0.4 1.3 GO:0019777 Atg12 transferase activity(GO:0019777)
0.4 1.5 GO:0003979 UDP-glucose 6-dehydrogenase activity(GO:0003979)
0.4 3.4 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.4 2.6 GO:0008118 N-acetyllactosaminide alpha-2,3-sialyltransferase activity(GO:0008118)
0.4 1.5 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
0.3 1.3 GO:0008117 sphinganine-1-phosphate aldolase activity(GO:0008117)
0.3 1.3 GO:1990931 oxidative DNA demethylase activity(GO:0035516) DNA-N1-methyladenine dioxygenase activity(GO:0043734) RNA N6-methyladenosine dioxygenase activity(GO:1990931)
0.3 0.9 GO:0004775 succinate-CoA ligase activity(GO:0004774) succinate-CoA ligase (ADP-forming) activity(GO:0004775) succinate-CoA ligase (GDP-forming) activity(GO:0004776)
0.3 0.9 GO:0071532 ankyrin repeat binding(GO:0071532)
0.3 1.4 GO:0016531 copper chaperone activity(GO:0016531)
0.3 1.1 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.3 3.2 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.2 0.9 GO:0003958 NADPH-hemoprotein reductase activity(GO:0003958)
0.2 1.1 GO:0030620 U2 snRNA binding(GO:0030620)
0.2 2.1 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.2 3.5 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.2 0.6 GO:0070905 glycine hydroxymethyltransferase activity(GO:0004372) serine binding(GO:0070905)
0.2 0.8 GO:0034511 U3 snoRNA binding(GO:0034511)
0.2 1.3 GO:0034452 dynactin binding(GO:0034452)
0.2 0.8 GO:0032183 SUMO binding(GO:0032183)
0.2 0.6 GO:0016263 glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity(GO:0016263) beta-1,3-galactosyltransferase activity(GO:0048531)
0.1 1.9 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.1 0.5 GO:0070324 thyroid hormone binding(GO:0070324)
0.1 3.2 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.1 0.9 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.1 0.6 GO:0017113 uracil binding(GO:0002058) pyrimidine nucleobase binding(GO:0002061) dihydropyrimidine dehydrogenase (NADP+) activity(GO:0017113)
0.1 1.5 GO:0061665 SUMO ligase activity(GO:0061665)
0.1 0.7 GO:0030619 U1 snRNA binding(GO:0030619)
0.1 0.8 GO:0033592 RNA strand annealing activity(GO:0033592) RNA strand-exchange activity(GO:0034057)
0.1 0.7 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.1 0.3 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.1 1.1 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.1 0.5 GO:0001735 prenylcysteine oxidase activity(GO:0001735)
0.1 0.5 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.1 1.3 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.1 1.4 GO:0017002 activin-activated receptor activity(GO:0017002)
0.1 2.2 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.1 0.8 GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
0.1 1.3 GO:0045159 myosin II binding(GO:0045159)
0.1 2.7 GO:0015036 disulfide oxidoreductase activity(GO:0015036)
0.1 8.0 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 0.3 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.1 1.1 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 3.0 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1 0.2 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.1 0.2 GO:0004377 GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity(GO:0004377)
0.1 1.0 GO:0017025 TBP-class protein binding(GO:0017025)
0.1 0.2 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.1 0.6 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 4.2 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.4 GO:0017091 AU-rich element binding(GO:0017091) mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.5 GO:0005537 mannose binding(GO:0005537)
0.0 1.0 GO:0016875 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.0 0.5 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 0.5 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
0.0 0.6 GO:0010181 FMN binding(GO:0010181)
0.0 0.9 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.9 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 1.7 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 4.8 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.1 GO:0015193 L-alanine transmembrane transporter activity(GO:0015180) L-proline transmembrane transporter activity(GO:0015193) alanine transmembrane transporter activity(GO:0022858)
0.0 0.9 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.8 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 2.6 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 1.9 GO:0003724 RNA helicase activity(GO:0003724)
0.0 0.1 GO:0039706 co-receptor binding(GO:0039706)
0.0 0.2 GO:0004977 melanocortin receptor activity(GO:0004977)
0.0 0.5 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.3 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.2 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0 0.3 GO:0031386 protein tag(GO:0031386)
0.0 0.9 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 1.2 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.0 0.3 GO:0030515 snoRNA binding(GO:0030515)
0.0 0.1 GO:1990756 protein binding, bridging involved in substrate recognition for ubiquitination(GO:1990756)
0.0 0.1 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.0 2.8 GO:0060090 binding, bridging(GO:0060090)
0.0 0.1 GO:0008297 single-stranded DNA exodeoxyribonuclease activity(GO:0008297)
0.0 0.2 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.5 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.1 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.0 0.5 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.3 GO:0034062 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0 0.2 GO:0022851 benzodiazepine receptor activity(GO:0008503) GABA-gated chloride ion channel activity(GO:0022851)
0.0 0.9 GO:0003697 single-stranded DNA binding(GO:0003697)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.2 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.1 1.6 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1 4.8 PID PLK1 PATHWAY PLK1 signaling events
0.1 1.5 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.1 2.4 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 1.4 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.7 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.4 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 1.2 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 0.8 PID BARD1 PATHWAY BARD1 signaling events
0.0 0.5 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.5 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.7 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.8 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.8 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 0.1 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 0.4 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0 0.6 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 1.9 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.3 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.1 1.4 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.1 1.6 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.1 3.8 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.1 1.1 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.1 1.2 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.1 0.3 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.1 1.5 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation
0.1 0.8 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.1 0.8 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.1 0.6 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.0 1.8 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 1.0 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 1.8 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 1.9 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.4 REACTOME SIGNALING BY NOTCH3 Genes involved in Signaling by NOTCH3
0.0 0.6 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.9 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.2 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.5 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 1.6 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.3 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.3 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.0 0.9 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0 0.5 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.5 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.2 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 0.4 REACTOME PROCESSING OF CAPPED INTRONLESS PRE MRNA Genes involved in Processing of Capped Intronless Pre-mRNA
0.0 0.2 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.0 0.1 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 0.5 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.0 0.3 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 0.2 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.7 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.5 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.2 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.6 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.6 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.2 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo