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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for alx4a+alx4b

Z-value: 0.42

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Transcription factors associated with alx4a+alx4b

Gene Symbol Gene ID Gene Info
alx4b
ENSDARG00000074442 ALX homeobox 4b
alx4a
ENSDARG00000088332 ALX homeobox 4a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
alx4bdr11_v1_chr18_+_38321039_38321039-0.932.8e-08Click!
alx4adr11_v1_chr7_-_26924903_26924903-0.312.1e-01Click!

Activity profile of alx4a+alx4b motif

Sorted Z-values of alx4a+alx4b motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr6_+_28208973 1.44 ENSDART00000171216
ENSDART00000171377
ENSDART00000167389
ENSDART00000166988
LSM2 (1 of many)
si:ch73-14h10.2
chr25_+_22320738 1.23 ENSDART00000073566
cyp11a1
cytochrome P450, family 11, subfamily A, polypeptide 1
chr10_-_34002185 1.23 ENSDART00000046599
zar1l
zygote arrest 1-like
chr12_-_4243268 1.21 ENSDART00000131275
zgc:92313
zgc:92313
chr9_+_54039006 1.18 ENSDART00000112441
tlr7
toll-like receptor 7
chr21_+_25777425 1.17 ENSDART00000021620
cldnd
claudin d
chr15_-_2519640 1.16 ENSDART00000047013
srprb
signal recognition particle receptor, B subunit
chr5_+_37903790 1.13 ENSDART00000162470
tmprss4b
transmembrane protease, serine 4b
chr8_+_45334255 1.07 ENSDART00000126848
ENSDART00000134161
ENSDART00000142322
ENSDART00000145011
ENSDART00000183560
pabpc1l
poly(A) binding protein, cytoplasmic 1-like
chr25_+_36292057 0.95 ENSDART00000152329
bmb
brambleberry
chr12_-_18578218 0.92 ENSDART00000125803
zdhhc4
zinc finger, DHHC-type containing 4
chr9_+_44994214 0.91 ENSDART00000141434
retsatl
retinol saturase (all-trans-retinol 13,14-reductase) like
chr10_+_11261576 0.89 ENSDART00000155333
hsdl2
hydroxysteroid dehydrogenase like 2
chr12_-_18578432 0.85 ENSDART00000122858
zdhhc4
zinc finger, DHHC-type containing 4
chr11_+_12811906 0.82 ENSDART00000123445
rtel1
regulator of telomere elongation helicase 1
chr1_-_55248496 0.80 ENSDART00000098615
nanos3
nanos homolog 3
chr10_-_34916208 0.79 ENSDART00000187371
ccna1
cyclin A1
chr20_-_49889111 0.76 ENSDART00000058858
kif13bb
kinesin family member 13Bb
chr12_-_33357655 0.75 ENSDART00000066233
ENSDART00000148165
slc16a3
solute carrier family 16 (monocarboxylate transporter), member 3
chr8_-_25034411 0.74 ENSDART00000135973
nfyal
nuclear transcription factor Y, alpha, like
chr9_-_23807032 0.74 ENSDART00000027443
esyt3
extended synaptotagmin-like protein 3
chr24_-_16980337 0.73 ENSDART00000183812
klhl15
kelch-like family member 15
chr17_-_40956035 0.70 ENSDART00000124715
si:dkey-16j16.4
si:dkey-16j16.4
chr20_+_29209926 0.68 ENSDART00000152949
ENSDART00000153016
katnbl1
katanin p80 subunit B-like 1
chr19_-_25149598 0.68 ENSDART00000162917
ptp4a3
protein tyrosine phosphatase type IVA, member 3
chr18_+_14619544 0.67 ENSDART00000010821
utp4
UTP4, small subunit processome component
chr21_+_21195487 0.67 ENSDART00000181746
ENSDART00000184832
rictorb
RPTOR independent companion of MTOR, complex 2b
chr8_+_11425048 0.66 ENSDART00000018739
tjp2b
tight junction protein 2b (zona occludens 2)
chr11_+_42474694 0.66 ENSDART00000056048
ENSDART00000184710
si:ch1073-165f9.2
si:ch1073-165f9.2
chr8_-_53044300 0.65 ENSDART00000191653
nr6a1a
nuclear receptor subfamily 6, group A, member 1a
chr10_+_33393829 0.64 ENSDART00000163458
ENSDART00000115379
zgc:153345
zgc:153345
chr8_+_23826985 0.64 ENSDART00000187430
mapk14a
mitogen-activated protein kinase 14a
chr19_-_18127808 0.63 ENSDART00000108627
snx10a
sorting nexin 10a
chr24_-_2450597 0.63 ENSDART00000188080
ENSDART00000093331
rreb1a
ras responsive element binding protein 1a
chr17_+_24318753 0.61 ENSDART00000064083
otx1
orthodenticle homeobox 1
chr21_+_27513859 0.61 ENSDART00000065420
pacs1a
phosphofurin acidic cluster sorting protein 1a
chr25_-_12902242 0.61 ENSDART00000164733
sept15
septin 15
chr14_-_1200854 0.61 ENSDART00000106672
arl9
ADP-ribosylation factor-like 9
chr9_+_48123224 0.61 ENSDART00000141610
klhl23
kelch-like family member 23
chr3_-_47128096 0.61 ENSDART00000063287
qtrt1
queuine tRNA-ribosyltransferase 1
chr7_+_57088920 0.61 ENSDART00000024076
scamp2l
secretory carrier membrane protein 2, like
chr11_+_5468629 0.60 ENSDART00000013203
cse1l
CSE1 chromosome segregation 1-like (yeast)
chr3_+_13848226 0.60 ENSDART00000184342
ilf3b
interleukin enhancer binding factor 3b
chr17_+_22577472 0.59 ENSDART00000045099
yipf4
Yip1 domain family, member 4
chr11_-_39118882 0.59 ENSDART00000113185
ENSDART00000156526
ap5b1
adaptor-related protein complex 5, beta 1 subunit
chr9_-_27398369 0.58 ENSDART00000186499
tex30
testis expressed 30
chr19_-_18127629 0.58 ENSDART00000187722
snx10a
sorting nexin 10a
chr1_+_31658011 0.58 ENSDART00000192203
poll
polymerase (DNA directed), lambda
chr22_-_10541712 0.57 ENSDART00000013933
si:dkey-42i9.4
si:dkey-42i9.4
chr16_+_54209504 0.57 ENSDART00000020033
xrcc1
X-ray repair complementing defective repair in Chinese hamster cells 1
chr3_-_61494840 0.56 ENSDART00000101957
baiap2l1b
BAI1-associated protein 2-like 1b
chr23_-_36303216 0.56 ENSDART00000188720
cbx5
chromobox homolog 5 (HP1 alpha homolog, Drosophila)
chr2_-_17392799 0.55 ENSDART00000136470
ENSDART00000141188
st3gal3b
ST3 beta-galactoside alpha-2,3-sialyltransferase 3b
chr24_-_32173754 0.55 ENSDART00000048633
trdmt1
tRNA aspartic acid methyltransferase 1
chr18_-_15551360 0.55 ENSDART00000159915
ENSDART00000172690
ppfibp1b
PTPRF interacting protein, binding protein 1b (liprin beta 1)
chr15_+_12429206 0.55 ENSDART00000168997
tmprss4a
transmembrane protease, serine 4a
chr14_+_8940326 0.54 ENSDART00000159920
rps6kal
ribosomal protein S6 kinase a, like
chr13_-_48161568 0.54 ENSDART00000109469
ENSDART00000188052
ENSDART00000193446
ENSDART00000189509
ENSDART00000184810
golga4
golgin A4
chr24_-_25166720 0.53 ENSDART00000141601
phldb2b
pleckstrin homology-like domain, family B, member 2b
chr10_-_2788668 0.53 ENSDART00000131749
ENSDART00000124356
ENSDART00000085031
ash2l
ash2 (absent, small, or homeotic)-like (Drosophila)
chr10_+_15255198 0.52 ENSDART00000139047
ENSDART00000172107
ENSDART00000183413
ENSDART00000185314
vldlr
very low density lipoprotein receptor
chr21_+_43172506 0.52 ENSDART00000121725
zcchc10
zinc finger, CCHC domain containing 10
chr6_+_36821621 0.52 ENSDART00000104157
tmem45a
transmembrane protein 45a
chr6_-_55399214 0.52 ENSDART00000168367
ctsa
cathepsin A
chr13_-_18695289 0.52 ENSDART00000176809
sfxn3
sideroflexin 3
chr19_+_27858866 0.51 ENSDART00000140336
nsun2
NOP2/Sun RNA methyltransferase family, member 2
chr5_+_1624359 0.50 ENSDART00000165431
PPP1CC
protein phosphatase 1 catalytic subunit gamma
chr3_-_26806032 0.50 ENSDART00000143710
pigq
phosphatidylinositol glycan anchor biosynthesis, class Q
chr7_+_24023653 0.49 ENSDART00000141165
tinf2
TERF1 (TRF1)-interacting nuclear factor 2
chr18_+_39487486 0.48 ENSDART00000126978
acadl
acyl-CoA dehydrogenase long chain
chr21_+_13387965 0.48 ENSDART00000134347
zgc:113162
zgc:113162
chr6_+_3717613 0.48 ENSDART00000184330
ssb
Sjogren syndrome antigen B (autoantigen La)
chr22_-_10541372 0.48 ENSDART00000179708
si:dkey-42i9.4
si:dkey-42i9.4
chr20_-_51831816 0.48 ENSDART00000060505
mia3
melanoma inhibitory activity family, member 3
chr12_-_18577983 0.47 ENSDART00000193262
zdhhc4
zinc finger, DHHC-type containing 4
chr20_+_29209767 0.47 ENSDART00000141252
katnbl1
katanin p80 subunit B-like 1
chr9_-_11676491 0.47 ENSDART00000022358
zc3h15
zinc finger CCCH-type containing 15
chr1_+_45663727 0.47 ENSDART00000038574
ENSDART00000141144
ENSDART00000149565
trappc5
trafficking protein particle complex 5
chr7_-_41746427 0.47 ENSDART00000174232
arl8
ADP-ribosylation factor-like 8
chr25_-_25058508 0.46 ENSDART00000087570
ENSDART00000178891
FQ311928.1

chr25_-_21031007 0.46 ENSDART00000138985
gnaia
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide a
chr13_+_33268657 0.46 ENSDART00000002095
tmem39b
transmembrane protein 39B
chr3_+_26288981 0.46 ENSDART00000163500
rhot1a
ras homolog family member T1a
chr22_+_17828267 0.46 ENSDART00000136016
hapln4
hyaluronan and proteoglycan link protein 4
chr11_-_26832685 0.45 ENSDART00000153519
iqsec1b
IQ motif and Sec7 domain 1b
chr11_+_31609481 0.45 ENSDART00000124830
ENSDART00000162768
zgc:162816
zgc:162816
chr3_-_34136368 0.45 ENSDART00000136900
ENSDART00000186125
clpp
caseinolytic mitochondrial matrix peptidase proteolytic subunit
chr14_-_48765262 0.45 ENSDART00000166463
cnot6b
CCR4-NOT transcription complex, subunit 6b
chr2_+_6253246 0.45 ENSDART00000058256
ENSDART00000076700
zp3b
zona pellucida glycoprotein 3b
chr21_+_15592426 0.45 ENSDART00000138207
smarcb1b
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1b
chr23_+_4709607 0.45 ENSDART00000166503
ENSDART00000158752
ENSDART00000163860
ENSDART00000172739
raf1a
raf1a
Raf-1 proto-oncogene, serine/threonine kinase a
Raf-1 proto-oncogene, serine/threonine kinase a
chr6_-_8597735 0.45 ENSDART00000151294
fopnl
fgfr1op N-terminal like
chr14_+_16287968 0.45 ENSDART00000106593
prpf19
pre-mRNA processing factor 19
chr5_+_872299 0.44 ENSDART00000130042
fubp3
far upstream element (FUSE) binding protein 3
chr12_+_47081783 0.44 ENSDART00000158568
mtr
5-methyltetrahydrofolate-homocysteine methyltransferase
chr24_+_19415124 0.44 ENSDART00000186931
sulf1
sulfatase 1
chr6_-_26080384 0.43 ENSDART00000157181
ENSDART00000154568
hs2st1b
heparan sulfate 2-O-sulfotransferase 1b
chr2_-_57110477 0.43 ENSDART00000181132
slc25a42
solute carrier family 25, member 42
chr9_+_28140089 0.43 ENSDART00000046880
plekhm3
pleckstrin homology domain containing, family M, member 3
chr12_-_31726748 0.43 ENSDART00000153174
srsf2a
serine/arginine-rich splicing factor 2a
chr12_+_5358409 0.43 ENSDART00000152632
plce1
phospholipase C, epsilon 1
chr20_+_29209615 0.43 ENSDART00000062350
katnbl1
katanin p80 subunit B-like 1
chr3_-_30488063 0.42 ENSDART00000055393
ENSDART00000151367
med25
mediator complex subunit 25
chr5_-_15283509 0.42 ENSDART00000052712
gnb1l
guanine nucleotide binding protein (G protein), beta polypeptide 1-like
chr7_-_8712148 0.42 ENSDART00000065488
tex261
testis expressed 261
chr1_-_6085750 0.42 ENSDART00000138891
si:ch1073-345a8.1
si:ch1073-345a8.1
chr7_-_31922432 0.42 ENSDART00000188398
lin7c
lin-7 homolog C (C. elegans)
chr2_-_58183499 0.42 ENSDART00000172281
ENSDART00000186262
si:ch1073-185p12.2
si:ch1073-185p12.2
chr16_-_22544047 0.42 ENSDART00000131657
cgna
cingulin a
chr3_-_34136778 0.42 ENSDART00000131951
clpp
caseinolytic mitochondrial matrix peptidase proteolytic subunit
chr20_+_36812368 0.41 ENSDART00000062931
abracl
ABRA C-terminal like
chr6_-_12912606 0.41 ENSDART00000164640
ical1
islet cell autoantigen 1-like
chr16_-_42965192 0.41 ENSDART00000113714
mtx1a
metaxin 1a
chr6_-_34838397 0.41 ENSDART00000060169
ENSDART00000169605
mier1a
mesoderm induction early response 1a, transcriptional regulator
chr5_+_25733774 0.41 ENSDART00000137088
ENSDART00000098467
abhd17b
abhydrolase domain containing 17B
chr8_-_11324143 0.40 ENSDART00000008215
pip5k1bb
phosphatidylinositol-4-phosphate 5-kinase, type I, beta b
chr2_-_17393216 0.40 ENSDART00000123137
st3gal3b
ST3 beta-galactoside alpha-2,3-sialyltransferase 3b
chr4_-_3353595 0.40 ENSDART00000009076
pik3cg
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
chr13_-_36798204 0.39 ENSDART00000012357
sav1
salvador family WW domain containing protein 1
chr6_-_10034145 0.39 ENSDART00000185999
nudt15
nudix (nucleoside diphosphate linked moiety X)-type motif 15
chr3_+_13850163 0.39 ENSDART00000164872
ilf3b
interleukin enhancer binding factor 3b
chr15_-_43284021 0.39 ENSDART00000041677
serpine2
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
chr20_+_715739 0.38 ENSDART00000136768
myo6a
myosin VIa
chr9_+_38588081 0.38 ENSDART00000031127
ENSDART00000131784
snx4
sorting nexin 4
chr3_-_26787430 0.38 ENSDART00000087047
rab40c
RAB40c, member RAS oncogene family
chr23_-_16692312 0.38 ENSDART00000046784
fkbp1ab
FK506 binding protein 1Ab
chr16_+_33992418 0.38 ENSDART00000101885
ENSDART00000130540
zdhhc18a
zinc finger, DHHC-type containing 18a
chr11_-_669558 0.38 ENSDART00000173450
pparg
peroxisome proliferator-activated receptor gamma
chr19_-_82504 0.38 ENSDART00000027864
ENSDART00000160560
hnrnpr
heterogeneous nuclear ribonucleoprotein R
chr1_-_51038885 0.37 ENSDART00000035150
spast
spastin
chr21_-_4793686 0.37 ENSDART00000158232
notch1a
notch 1a
chr14_+_989733 0.37 ENSDART00000161487
ENSDART00000127317
si:ch73-308l14.2
si:ch73-308l14.2
chr22_-_20812822 0.37 ENSDART00000193778
dot1l
DOT1-like histone H3K79 methyltransferase
chr1_+_418869 0.37 ENSDART00000152173
tpp2
tripeptidyl peptidase 2
chr3_-_14498295 0.36 ENSDART00000172102
elof1
ELF1 homolog, elongation factor 1
chr16_-_25368048 0.36 ENSDART00000132445
rbfa
ribosome binding factor A
chr5_+_6672870 0.36 ENSDART00000126598
pxna
paxillin a
chr9_-_34509997 0.36 ENSDART00000169114
ppp2r3b
protein phosphatase 2, regulatory subunit B'', beta
chr25_+_7241084 0.36 ENSDART00000190501
ENSDART00000190588
hmg20a
high mobility group 20A
chr8_-_49728590 0.36 ENSDART00000135714
ENSDART00000138810
ENSDART00000098319
gkap1
G kinase anchoring protein 1
chr18_+_16750080 0.36 ENSDART00000136320
rnf141
ring finger protein 141
chr10_-_13343831 0.35 ENSDART00000135941
il11ra
interleukin 11 receptor, alpha
chr20_+_39250673 0.35 ENSDART00000153003
reps1
RALBP1 associated Eps domain containing 1
chr9_+_24065855 0.35 ENSDART00000161468
ENSDART00000171577
ENSDART00000172743
ENSDART00000159324
ENSDART00000079689
ENSDART00000023196
ENSDART00000101577
lrrfip1a
leucine rich repeat (in FLII) interacting protein 1a
chr23_-_2901167 0.35 ENSDART00000165955
ENSDART00000190616
zhx3
zinc fingers and homeoboxes 3
chr17_-_27048537 0.34 ENSDART00000050018
ENSDART00000193861
cnksr1
connector enhancer of kinase suppressor of Ras 1
chr5_-_11809710 0.34 ENSDART00000186998
ENSDART00000181363
ENSDART00000180681
nf2a
neurofibromin 2a (merlin)
chr20_+_32552912 0.34 ENSDART00000009691
scml4
Scm polycomb group protein like 4
chr9_+_16241656 0.34 ENSDART00000154326
si:ch211-261p9.4
si:ch211-261p9.4
chr21_+_25236297 0.33 ENSDART00000112783
tmem45b
transmembrane protein 45B
chr21_-_44081540 0.33 ENSDART00000130833
FO704810.1

chr11_+_45388126 0.33 ENSDART00000167826
ENSDART00000171274
srsf11
serine/arginine-rich splicing factor 11
chr23_-_20051369 0.33 ENSDART00000049836
bgnb
biglycan b
chr2_+_47708853 0.33 ENSDART00000124307
mbnl1
muscleblind-like splicing regulator 1
chr6_-_46053300 0.33 ENSDART00000169722
ca16b
carbonic anhydrase XVI b
chr16_-_28658341 0.33 ENSDART00000148456
abcb4
ATP-binding cassette, sub-family B (MDR/TAP), member 4
chr13_-_35808904 0.32 ENSDART00000171667
map3k4
mitogen-activated protein kinase kinase kinase 4
chr17_+_30369396 0.32 ENSDART00000076611
greb1
growth regulation by estrogen in breast cancer 1
chr24_-_36238054 0.32 ENSDART00000155725
tmem241
transmembrane protein 241
chr15_-_41310340 0.32 ENSDART00000192112
si:dkey-75b17.1
si:dkey-75b17.1
chr22_+_9522971 0.32 ENSDART00000110048
strip1
striatin interacting protein 1
chr6_-_50730749 0.31 ENSDART00000157153
ENSDART00000110441
pigu
phosphatidylinositol glycan anchor biosynthesis, class U
chr20_+_22799857 0.31 ENSDART00000058527
scfd2
sec1 family domain containing 2
chr9_-_34937025 0.31 ENSDART00000137888
cdc16
cell division cycle 16 homolog (S. cerevisiae)
chr22_+_2769236 0.31 ENSDART00000141836
si:dkey-20i20.10
si:dkey-20i20.10
chr22_+_737211 0.31 ENSDART00000017305
znf76
zinc finger protein 76
chr3_+_39579393 0.31 ENSDART00000055170
cln3
ceroid-lipofuscinosis, neuronal 3
chr19_-_3724605 0.31 ENSDART00000123757
smim13
small integral membrane protein 13
chr22_+_23359369 0.31 ENSDART00000170886
dennd1b
DENN/MADD domain containing 1B
chr16_-_27677930 0.30 ENSDART00000145991
tbrg4
transforming growth factor beta regulator 4
chr24_-_11076400 0.30 ENSDART00000003195
chmp4c
charged multivesicular body protein 4C
chr6_+_40922572 0.30 ENSDART00000133599
ENSDART00000002728
ENSDART00000145153
eif4enif1
eukaryotic translation initiation factor 4E nuclear import factor 1
chr5_-_32396929 0.29 ENSDART00000023977
fbxw2
F-box and WD repeat domain containing 2
chr1_+_35985813 0.29 ENSDART00000179634
ENSDART00000139636
ENSDART00000175902
zgc:152968
zgc:152968
chr5_-_66397688 0.29 ENSDART00000161483
hip1rb
huntingtin interacting protein 1 related b
chr12_+_3571770 0.29 ENSDART00000164707
ENSDART00000189819
coa3a
cytochrome C oxidase assembly factor 3a
chr20_-_2290529 0.29 ENSDART00000134695
EPB41L2
si:ch73-18b11.1
chr7_+_6941583 0.29 ENSDART00000160709
ENSDART00000157634
rbm14b
RNA binding motif protein 14b
chr19_+_46158078 0.29 ENSDART00000183933
ENSDART00000164055
cap2
CAP, adenylate cyclase-associated protein, 2 (yeast)
chr9_+_29643036 0.29 ENSDART00000023210
ENSDART00000175160
trim13
tripartite motif containing 13
chr4_-_2975461 0.29 ENSDART00000150794
plekha5
pleckstrin homology domain containing, family A member 5
chr12_-_3773869 0.29 ENSDART00000092983
si:ch211-166g5.4
si:ch211-166g5.4
chr3_+_12593558 0.29 ENSDART00000186891
ENSDART00000159252
abca3b
ATP-binding cassette, sub-family A (ABC1), member 3b
chr10_-_105100 0.29 ENSDART00000145716
ttc3
tetratricopeptide repeat domain 3
chr12_-_26153101 0.29 ENSDART00000076051
opn4b
opsin 4b
chr23_+_1029450 0.29 ENSDART00000189196
si:zfos-905g2.1
si:zfos-905g2.1
chr19_+_26923274 0.28 ENSDART00000148439
ENSDART00000148877
nelfe
negative elongation factor complex member E
chr13_-_4018888 0.28 ENSDART00000058238
tjap1
tight junction associated protein 1 (peripheral)
chr8_+_48942470 0.28 ENSDART00000005464
ENSDART00000132035
rer1
retention in endoplasmic reticulum sorting receptor 1
chr24_+_39641991 0.28 ENSDART00000142182
luc7l
LUC7-like (S. cerevisiae)
chr1_+_52792439 0.27 ENSDART00000123972
smarca5
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
chr19_-_7441686 0.27 ENSDART00000168194
gabpb2a
GA binding protein transcription factor, beta subunit 2a
chr20_-_24182689 0.27 ENSDART00000171184
map3k7
mitogen-activated protein kinase kinase kinase 7
chr1_-_55118745 0.27 ENSDART00000133915
sertad2a
SERTA domain containing 2a
chr17_-_49412313 0.27 ENSDART00000152100
mthfd1b
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1b
chr13_+_38817871 0.27 ENSDART00000187708
col19a1
collagen, type XIX, alpha 1
chr12_-_19119176 0.27 ENSDART00000149180
aco2
aconitase 2, mitochondrial
chr5_+_60590796 0.27 ENSDART00000159859
tmem132e
transmembrane protein 132E
chr2_+_25315591 0.27 ENSDART00000161386
fndc3ba
fibronectin type III domain containing 3Ba
chr3_+_26813058 0.27 ENSDART00000055537
socs1a
suppressor of cytokine signaling 1a

Network of associatons between targets according to the STRING database.

First level regulatory network of alx4a+alx4b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0034154 toll-like receptor 7 signaling pathway(GO:0034154)
0.2 1.2 GO:0006700 C21-steroid hormone biosynthetic process(GO:0006700)
0.2 1.2 GO:0070986 left/right axis specification(GO:0070986)
0.2 1.2 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.2 0.9 GO:0000741 karyogamy(GO:0000741) pronuclear fusion(GO:0007344)
0.2 0.7 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.2 0.6 GO:0040016 embryonic cleavage(GO:0040016)
0.1 0.4 GO:0051228 protein hexamerization(GO:0034214) mitotic spindle disassembly(GO:0051228) spindle disassembly(GO:0051230)
0.1 0.4 GO:0021531 spinal cord radial glial cell differentiation(GO:0021531)
0.1 0.6 GO:0000012 single strand break repair(GO:0000012)
0.1 0.5 GO:1903292 protein localization to Golgi membrane(GO:1903292)
0.1 0.4 GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518)
0.1 0.5 GO:0042772 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978) DNA damage response, signal transduction resulting in transcription(GO:0042772)
0.1 0.5 GO:0019254 carnitine metabolic process, CoA-linked(GO:0019254)
0.1 1.0 GO:0072386 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.1 0.4 GO:0034729 histone H3-K79 methylation(GO:0034729) regulation of transcription regulatory region DNA binding(GO:2000677)
0.1 0.8 GO:0032205 negative regulation of telomere maintenance(GO:0032205)
0.1 0.6 GO:0007589 body fluid secretion(GO:0007589)
0.1 0.5 GO:0060334 regulation of response to interferon-gamma(GO:0060330) regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.1 0.4 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.1 0.5 GO:1904356 regulation of telomere maintenance via telomere lengthening(GO:1904356)
0.1 0.4 GO:0036088 D-amino acid catabolic process(GO:0019478) D-serine catabolic process(GO:0036088) D-amino acid metabolic process(GO:0046416) D-serine metabolic process(GO:0070178)
0.1 0.4 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.1 0.2 GO:1904478 regulation of intestinal absorption(GO:1904478) regulation of intestinal lipid absorption(GO:1904729)
0.1 0.3 GO:0070131 regulation of mitochondrial translation(GO:0070129) positive regulation of mitochondrial translation(GO:0070131)
0.1 2.6 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.1 0.2 GO:1901006 ubiquinone-6 metabolic process(GO:1901004) ubiquinone-6 biosynthetic process(GO:1901006)
0.1 0.2 GO:0016446 somatic diversification of immune receptors via somatic mutation(GO:0002566) pyrimidine dimer repair(GO:0006290) somatic hypermutation of immunoglobulin genes(GO:0016446)
0.1 0.2 GO:0018872 arsonoacetate metabolic process(GO:0018872)
0.1 0.6 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.1 0.2 GO:0044406 virion attachment to host cell(GO:0019062) adhesion of symbiont to host(GO:0044406) adhesion of symbiont to host cell(GO:0044650)
0.1 0.2 GO:1903334 regulation of protein folding(GO:1903332) positive regulation of protein folding(GO:1903334) regulation of chaperone-mediated protein folding(GO:1903644) positive regulation of chaperone-mediated protein folding(GO:1903646)
0.1 0.7 GO:0038203 TORC2 signaling(GO:0038203)
0.1 0.2 GO:0002369 T cell cytokine production(GO:0002369)
0.1 1.3 GO:0045047 protein targeting to ER(GO:0045047) establishment of protein localization to endoplasmic reticulum(GO:0072599)
0.1 0.4 GO:0006203 dGTP catabolic process(GO:0006203) purine nucleoside triphosphate catabolic process(GO:0009146) purine deoxyribonucleoside triphosphate catabolic process(GO:0009217) dGTP metabolic process(GO:0046070)
0.1 0.4 GO:2000290 smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021910) regulation of myotome development(GO:2000290)
0.1 0.4 GO:0061055 myotome development(GO:0061055)
0.1 0.5 GO:0097345 mitochondrial outer membrane permeabilization(GO:0097345)
0.1 0.2 GO:0010142 farnesyl diphosphate biosynthetic process, mevalonate pathway(GO:0010142) isoprenoid biosynthetic process via mevalonate(GO:1902767)
0.0 0.2 GO:0036306 embryonic heart tube elongation(GO:0036306)
0.0 0.4 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.2 GO:0090155 regulation of sphingolipid biosynthetic process(GO:0090153) negative regulation of sphingolipid biosynthetic process(GO:0090155) negative regulation of ceramide biosynthetic process(GO:1900060) regulation of membrane lipid metabolic process(GO:1905038) regulation of ceramide biosynthetic process(GO:2000303)
0.0 0.2 GO:0090140 regulation of mitochondrial fission(GO:0090140)
0.0 0.3 GO:0015809 arginine transport(GO:0015809)
0.0 0.6 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.3 GO:1902038 positive regulation of hematopoietic stem cell differentiation(GO:1902038)
0.0 0.2 GO:0097250 mitochondrial respiratory chain supercomplex assembly(GO:0097250)
0.0 0.3 GO:0006621 protein retention in ER lumen(GO:0006621)
0.0 0.6 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.0 0.3 GO:0044528 regulation of mitochondrial mRNA stability(GO:0044528)
0.0 0.9 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 0.4 GO:0035479 angioblast cell migration from lateral mesoderm to midline(GO:0035479)
0.0 0.1 GO:0071236 cellular response to antibiotic(GO:0071236) cellular response to toxic substance(GO:0097237)
0.0 0.4 GO:1904263 positive regulation of TORC1 signaling(GO:1904263)
0.0 0.2 GO:1901906 diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.0 0.4 GO:0002084 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.0 0.2 GO:0051659 maintenance of mitochondrion location(GO:0051659)
0.0 0.2 GO:0000455 enzyme-directed rRNA pseudouridine synthesis(GO:0000455)
0.0 0.4 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 0.1 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
0.0 0.4 GO:0009086 methionine biosynthetic process(GO:0009086)
0.0 0.1 GO:1990575 mitochondrial ornithine transport(GO:0000066) ornithine transport(GO:0015822) L-ornithine transmembrane transport(GO:1903352) mitochondrial L-ornithine transmembrane transport(GO:1990575)
0.0 0.7 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.0 0.3 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.0 0.2 GO:0046149 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.0 0.2 GO:0010269 response to selenium ion(GO:0010269)
0.0 0.1 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.0 0.4 GO:0055090 acylglycerol homeostasis(GO:0055090) triglyceride homeostasis(GO:0070328)
0.0 0.1 GO:1900182 positive regulation of protein localization to nucleus(GO:1900182) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871)
0.0 0.5 GO:2000344 binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.0 0.5 GO:0035459 cargo loading into vesicle(GO:0035459)
0.0 0.3 GO:1901970 positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of chromosome segregation(GO:0051984) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.0 0.1 GO:0032782 canalicular bile acid transport(GO:0015722) bile acid secretion(GO:0032782)
0.0 0.3 GO:0035677 posterior lateral line neuromast hair cell development(GO:0035677)
0.0 0.6 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.0 0.2 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.6 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.0 0.4 GO:0051865 protein autoubiquitination(GO:0051865)
0.0 0.4 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0 0.2 GO:0015886 heme transport(GO:0015886) iron coordination entity transport(GO:1901678)
0.0 0.1 GO:0051292 nuclear pore complex assembly(GO:0051292)
0.0 0.5 GO:0006515 misfolded or incompletely synthesized protein catabolic process(GO:0006515)
0.0 0.3 GO:0035999 tetrahydrofolate interconversion(GO:0035999)
0.0 0.4 GO:0060021 palate development(GO:0060021)
0.0 0.6 GO:0006303 double-strand break repair via nonhomologous end joining(GO:0006303)
0.0 0.1 GO:0036336 dendritic cell chemotaxis(GO:0002407) dendritic cell migration(GO:0036336)
0.0 0.1 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.4 GO:0032836 glomerular basement membrane development(GO:0032836)
0.0 0.2 GO:0060754 mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.0 0.1 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350)
0.0 0.1 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 1.0 GO:0051607 defense response to virus(GO:0051607)
0.0 0.2 GO:0055117 regulation of cardiac muscle contraction(GO:0055117)
0.0 0.2 GO:0045670 regulation of osteoclast differentiation(GO:0045670)
0.0 0.3 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.1 GO:0006526 arginine biosynthetic process(GO:0006526)
0.0 0.5 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.2 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.0 0.3 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
0.0 0.0 GO:0048903 anterior lateral line neuromast hair cell differentiation(GO:0048903)
0.0 0.9 GO:0030917 midbrain-hindbrain boundary development(GO:0030917)
0.0 0.6 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 0.4 GO:0051014 actin filament severing(GO:0051014)
0.0 0.6 GO:0006400 tRNA modification(GO:0006400)
0.0 0.5 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 0.1 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.0 0.6 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.0 0.2 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.1 GO:0060836 lymphatic endothelial cell differentiation(GO:0060836) venous endothelial cell migration involved in lymph vessel development(GO:0060855)
0.0 0.4 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 0.0 GO:0045922 negative regulation of fatty acid metabolic process(GO:0045922)
0.0 0.4 GO:0007006 mitochondrial membrane organization(GO:0007006)
0.0 0.3 GO:0046838 phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855) inositol phosphate catabolic process(GO:0071545)
0.0 0.3 GO:0019933 cAMP-mediated signaling(GO:0019933)
0.0 0.8 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 1.3 GO:0045930 negative regulation of mitotic cell cycle(GO:0045930)
0.0 0.5 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.2 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0097124 cyclin A2-CDK2 complex(GO:0097124)
0.2 0.5 GO:1990072 TRAPPIII protein complex(GO:1990072)
0.1 0.7 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.1 0.4 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.1 0.6 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006) catalytic step 1 spliceosome(GO:0071012)
0.1 0.7 GO:0035060 brahma complex(GO:0035060)
0.1 0.4 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.1 0.2 GO:0032301 MutSalpha complex(GO:0032301)
0.1 0.7 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.1 0.2 GO:0072380 TRC complex(GO:0072380)
0.1 0.2 GO:0089701 U2AF(GO:0089701)
0.1 0.4 GO:0001401 mitochondrial sorting and assembly machinery complex(GO:0001401)
0.1 1.2 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 0.2 GO:0035339 SPOTS complex(GO:0035339)
0.0 0.3 GO:0016589 NURF complex(GO:0016589)
0.0 0.6 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.4 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.0 0.2 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.5 GO:0034361 very-low-density lipoprotein particle(GO:0034361)
0.0 0.1 GO:0034457 Mpp10 complex(GO:0034457)
0.0 0.5 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.6 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.3 GO:0032021 NELF complex(GO:0032021)
0.0 0.6 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.2 GO:0005674 transcription factor TFIIF complex(GO:0005674)
0.0 0.7 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.7 GO:0071004 U2-type prespliceosome(GO:0071004) prespliceosome(GO:0071010)
0.0 0.9 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.8 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.0 0.7 GO:0030686 90S preribosome(GO:0030686)
0.0 0.5 GO:0045180 basal cortex(GO:0045180)
0.0 0.7 GO:0043186 P granule(GO:0043186)
0.0 0.3 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.1 GO:1902636 kinociliary basal body(GO:1902636)
0.0 0.5 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.1 GO:0042584 chromaffin granule membrane(GO:0042584)
0.0 0.5 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 0.6 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 2.1 GO:0070160 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 0.3 GO:0005682 U5 snRNP(GO:0005682)
0.0 0.1 GO:0071797 LUBAC complex(GO:0071797)
0.0 0.7 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 0.1 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.1 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.2 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.7 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.2 GO:0033202 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 1.0 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 0.4 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.3 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.4 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.5 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.1 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.0 0.3 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0016713 cholesterol monooxygenase (side-chain-cleaving) activity(GO:0008386) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.2 0.8 GO:0070182 DNA polymerase binding(GO:0070182)
0.2 0.5 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.1 0.4 GO:0004394 heparan sulfate 2-O-sulfotransferase activity(GO:0004394)
0.1 0.4 GO:0071077 coenzyme A transmembrane transporter activity(GO:0015228) adenosine 3',5'-bisphosphate transmembrane transporter activity(GO:0071077) AMP transmembrane transporter activity(GO:0080122)
0.1 1.0 GO:0008118 N-acetyllactosaminide alpha-2,3-sialyltransferase activity(GO:0008118)
0.1 0.5 GO:0030228 lipoprotein particle receptor activity(GO:0030228)
0.1 0.5 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
0.1 0.3 GO:0015462 protein-transmembrane transporting ATPase activity(GO:0015462) efflux transmembrane transporter activity(GO:0015562)
0.1 0.7 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.1 0.4 GO:0097016 L27 domain binding(GO:0097016)
0.1 0.5 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.1 1.0 GO:0035925 AU-rich element binding(GO:0017091) mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.1 0.3 GO:0008179 adenylate cyclase binding(GO:0008179)
0.1 0.9 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.1 0.4 GO:0048487 beta-tubulin binding(GO:0048487)
0.1 0.4 GO:0031151 histone methyltransferase activity (H3-K79 specific)(GO:0031151)
0.1 0.5 GO:0016841 ammonia-lyase activity(GO:0016841)
0.1 0.3 GO:0003994 aconitate hydratase activity(GO:0003994)
0.1 0.5 GO:0022889 serine transmembrane transporter activity(GO:0022889)
0.1 0.9 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.1 0.2 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.1 1.1 GO:0008266 poly(U) RNA binding(GO:0008266)
0.1 0.4 GO:0070644 vitamin D response element binding(GO:0070644)
0.1 0.2 GO:0032138 guanine/thymine mispair binding(GO:0032137) single base insertion or deletion binding(GO:0032138) single thymine insertion binding(GO:0032143) oxidized DNA binding(GO:0032356) oxidized purine DNA binding(GO:0032357) mismatch repair complex binding(GO:0032404) MutLalpha complex binding(GO:0032405)
0.1 0.2 GO:0030791 arsenite methyltransferase activity(GO:0030791) methylarsonite methyltransferase activity(GO:0030792)
0.1 0.7 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.1 0.4 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.1 0.3 GO:0003958 NADPH-hemoprotein reductase activity(GO:0003958)
0.1 0.7 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.1 2.6 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1 0.4 GO:0031419 cobalamin binding(GO:0031419)
0.1 0.2 GO:0019145 aminobutyraldehyde dehydrogenase activity(GO:0019145) 4-trimethylammoniobutyraldehyde dehydrogenase activity(GO:0047105)
0.1 0.2 GO:0004421 hydroxymethylglutaryl-CoA synthase activity(GO:0004421)
0.0 0.2 GO:0061656 SUMO conjugating enzyme activity(GO:0061656)
0.0 0.2 GO:0001096 TFIIF-class transcription factor binding(GO:0001096)
0.0 0.5 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.0 0.2 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.5 GO:0035804 structural constituent of egg coat(GO:0035804)
0.0 2.0 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 0.3 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.0 0.3 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.4 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812)
0.0 0.2 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.5 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.2 GO:0000298 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.0 0.5 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.3 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.2 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.0 1.8 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.1 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.0 0.6 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.2 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.0 0.1 GO:0015432 canalicular bile acid transmembrane transporter activity(GO:0015126) bile acid-exporting ATPase activity(GO:0015432)
0.0 0.2 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.6 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.2 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.0 0.9 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.1 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.0 0.5 GO:0031267 small GTPase binding(GO:0031267)
0.0 0.1 GO:0034618 arginine binding(GO:0034618)
0.0 0.4 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.6 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.6 GO:0003684 damaged DNA binding(GO:0003684)
0.0 0.3 GO:0070403 NAD+ binding(GO:0070403)
0.0 0.1 GO:0070259 tyrosyl-DNA phosphodiesterase activity(GO:0070259)
0.0 0.5 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 0.2 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 0.4 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.4 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.5 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.4 GO:0016307 phosphatidylinositol phosphate kinase activity(GO:0016307)
0.0 0.2 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 0.1 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.0 0.1 GO:0033192 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.1 GO:0001607 neuromedin U receptor activity(GO:0001607)
0.0 0.5 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.1 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.3 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.3 GO:0008252 nucleotidase activity(GO:0008252)
0.0 2.4 GO:0035091 phosphatidylinositol binding(GO:0035091)
0.0 0.6 GO:0044325 ion channel binding(GO:0044325)
0.0 0.4 GO:0004629 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.0 2.3 GO:0042802 identical protein binding(GO:0042802)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 1.6 PID AURORA B PATHWAY Aurora B signaling
0.0 0.3 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.6 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.5 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.7 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.6 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.3 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.4 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.3 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.2 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.5 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.5 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 0.3 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.3 PID IL3 PATHWAY IL3-mediated signaling events
0.0 0.5 PID P53 REGULATION PATHWAY p53 pathway
0.0 0.4 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 0.5 PID TELOMERASE PATHWAY Regulation of Telomerase

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.1 1.2 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.1 0.2 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.1 0.3 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.1 0.9 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.8 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.4 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.8 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.4 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0 0.6 REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.0 0.5 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.5 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 1.2 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.3 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 0.4 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.4 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation
0.0 0.4 REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.0 0.4 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.2 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 0.7 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.2 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 1.6 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.3 REACTOME PHOSPHORYLATION OF THE APC C Genes involved in Phosphorylation of the APC/C
0.0 0.5 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.0 0.1 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.3 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing