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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for arid3a+arid3b+arid3c

Z-value: 1.39

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Transcription factors associated with arid3a+arid3b+arid3c

Gene Symbol Gene ID Gene Info
arid3c
ENSDARG00000067729 AT rich interactive domain 3C (BRIGHT-like)
arid3a
ENSDARG00000070843 AT rich interactive domain 3A (BRIGHT-like)
arid3b
ENSDARG00000104034 AT rich interactive domain 3B (BRIGHT-like)
arid3c
ENSDARG00000114447 AT rich interactive domain 3C (BRIGHT-like)

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
arid3bdr11_v1_chr25_-_29074064_290740640.896.5e-07Click!
arid3cdr11_v1_chr5_+_41322783_41322783-0.772.0e-04Click!
arid3adr11_v1_chr11_+_5681762_56817620.718.8e-04Click!

Activity profile of arid3a+arid3b+arid3c motif

Sorted Z-values of arid3a+arid3b+arid3c motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr10_+_45031398 7.77 ENSDART00000160536
gnsb
glucosamine (N-acetyl)-6-sulfatase (Sanfilippo disease IIID), b
chr21_-_42831033 7.51 ENSDART00000160998
stk10
serine/threonine kinase 10
chr17_-_1174960 5.03 ENSDART00000161202
dnajc17
DnaJ (Hsp40) homolog, subfamily C, member 17
chr17_-_4245902 4.76 ENSDART00000151851
gdf3
growth differentiation factor 3
chr14_+_46342882 4.31 ENSDART00000193707
ENSDART00000060577
tmem33
transmembrane protein 33
chr15_-_31109760 3.47 ENSDART00000154254
ksr1b
kinase suppressor of ras 1b
chr5_+_69650148 3.41 ENSDART00000097244
gtf2h3
general transcription factor IIH, polypeptide 3
chr8_-_29930821 3.40 ENSDART00000125173
ercc6l2
excision repair cross-complementation group 6-like 2
chr12_+_1609563 3.03 ENSDART00000163559
SLC39A11
solute carrier family 39 member 11
chr21_+_43172506 2.98 ENSDART00000121725
zcchc10
zinc finger, CCHC domain containing 10
chr15_+_38308421 2.90 ENSDART00000129941
si:dkey-24p1.6
si:dkey-24p1.6
chr12_-_48188928 2.89 ENSDART00000184384
pald1a
phosphatase domain containing, paladin 1a
chr23_+_2666944 2.82 ENSDART00000192861
CABZ01057928.1

chr7_-_8712148 2.77 ENSDART00000065488
tex261
testis expressed 261
chr7_+_9189547 2.76 ENSDART00000169783
pcsk6
proprotein convertase subtilisin/kexin type 6
chr12_-_13650344 2.76 ENSDART00000124364
ENSDART00000124638
ENSDART00000171929
stat5b
signal transducer and activator of transcription 5b
chr4_-_5775507 2.69 ENSDART00000021753
ccnc
cyclin C
chr6_-_8360918 2.62 ENSDART00000004716
acp5a
acid phosphatase 5a, tartrate resistant
chr17_-_7060477 2.60 ENSDART00000081797
sash1b
SAM and SH3 domain containing 1b
chr7_+_36467315 2.52 ENSDART00000138893
aktip
akt interacting protein
chr10_+_16911951 2.49 ENSDART00000164933
UNC13B (1 of many)
unc-13 homolog B
chr18_+_11858397 2.48 ENSDART00000133762
tmtc2b
transmembrane and tetratricopeptide repeat containing 2b
chr5_+_44895949 2.48 ENSDART00000193822
kank1a
KN motif and ankyrin repeat domains 1a
chr3_+_7808459 2.41 ENSDART00000162374
hook2
hook microtubule-tethering protein 2
chr21_-_20322816 2.40 ENSDART00000135472
zgc:86764
zgc:86764
chr19_+_4139065 2.31 ENSDART00000172524
si:dkey-218f9.10
si:dkey-218f9.10
chr14_+_30340251 2.26 ENSDART00000148448
mtus1a
microtubule associated tumor suppressor 1a
chr5_-_42180205 2.21 ENSDART00000145247
fam222ba
family with sequence similarity 222, member Ba
chr5_+_22579975 2.20 ENSDART00000080877
tnfsf10l4
tumor necrosis factor (ligand) superfamily, member 10 like 4
chr18_+_39416357 2.09 ENSDART00000183174
ENSDART00000127955
ENSDART00000171303
lysmd2
LysM, putative peptidoglycan-binding, domain containing 2
chr12_-_18961289 2.09 ENSDART00000168405
ep300a
E1A binding protein p300 a
chr20_+_35208020 2.05 ENSDART00000153315
ENSDART00000045135
fbxo16
F-box protein 16
chr1_-_52790724 2.02 ENSDART00000139577
ENSDART00000100937
patl1
protein associated with topoisomerase II homolog 1 (yeast)
chr9_-_27398369 1.97 ENSDART00000186499
tex30
testis expressed 30
chr19_+_25971000 1.95 ENSDART00000089836
jarid2b
jumonji, AT rich interactive domain 2b
chr14_+_16287968 1.92 ENSDART00000106593
prpf19
pre-mRNA processing factor 19
chr7_+_57088920 1.86 ENSDART00000024076
scamp2l
secretory carrier membrane protein 2, like
chr18_-_48296793 1.85 ENSDART00000032184
ENSDART00000193076
CABZ01069595.1

chr24_-_15208414 1.83 ENSDART00000145978
rttn
rotatin
chr16_-_42461263 1.80 ENSDART00000109259
smarcc1a
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1a
chr17_-_29213710 1.79 ENSDART00000076481
ehd4
EH-domain containing 4
chr4_-_25911609 1.78 ENSDART00000186958
ENSDART00000175487
fgd6
FYVE, RhoGEF and PH domain containing 6
chr2_-_57916317 1.75 ENSDART00000183930
si:dkeyp-68b7.7
si:dkeyp-68b7.7
chr5_+_5398966 1.73 ENSDART00000139553
mapkap1
mitogen-activated protein kinase associated protein 1
chr17_+_16046314 1.71 ENSDART00000154554
ENSDART00000154338
ENSDART00000155336
si:ch73-204p21.2
si:ch73-204p21.2
chr15_+_20530649 1.70 ENSDART00000186312
tnfaip1
tumor necrosis factor, alpha-induced protein 1 (endothelial)
chr7_-_51749683 1.70 ENSDART00000083190
hdac8
histone deacetylase 8
chr24_+_37484661 1.70 ENSDART00000165125
ENSDART00000109221
wdr90
WD repeat domain 90
chr22_+_2751887 1.63 ENSDART00000133652
si:dkey-20i20.11
si:dkey-20i20.11
chr23_-_24343363 1.59 ENSDART00000166392
fam131c
family with sequence similarity 131, member C
chr17_+_22311413 1.58 ENSDART00000151929
slc8a1b
solute carrier family 8 (sodium/calcium exchanger), member 1b
chr2_+_25657958 1.58 ENSDART00000161407
tnika
TRAF2 and NCK interacting kinase a
chr7_-_51749895 1.58 ENSDART00000175523
ENSDART00000189639
hdac8
histone deacetylase 8
chr3_-_34136368 1.54 ENSDART00000136900
ENSDART00000186125
clpp
caseinolytic mitochondrial matrix peptidase proteolytic subunit
chr14_+_35428152 1.54 ENSDART00000172597
sytl4
synaptotagmin-like 4
chr14_-_16082806 1.54 ENSDART00000165656
mxd3
MAX dimerization protein 3
chr22_-_10752471 1.51 ENSDART00000081191
sass6
SAS-6 centriolar assembly protein
chr4_-_13931508 1.50 ENSDART00000067174
zcrb1
zinc finger CCHC-type and RNA binding motif 1
chr24_-_32173754 1.49 ENSDART00000048633
trdmt1
tRNA aspartic acid methyltransferase 1
chr5_+_27404946 1.48 ENSDART00000121886
ENSDART00000005025
hdr
hematopoietic death receptor
chr19_-_7406933 1.48 ENSDART00000151137
oxr1b
oxidation resistance 1b
chr8_+_3820134 1.48 ENSDART00000122454
citb
citron rho-interacting serine/threonine kinase b
chr22_+_30047245 1.47 ENSDART00000142857
ENSDART00000141247
ENSDART00000140015
ENSDART00000040538
add3a
adducin 3 (gamma) a
chr11_-_2504750 1.45 ENSDART00000173149
dgkab
diacylglycerol kinase, alpha b
chr5_-_25576462 1.45 ENSDART00000165147
si:dkey-229d2.4
si:dkey-229d2.4
chr12_+_38774860 1.43 ENSDART00000130371
kif19
kinesin family member 19
chr11_-_43200994 1.42 ENSDART00000164700
sptbn1
spectrin, beta, non-erythrocytic 1
chr11_+_2687395 1.42 ENSDART00000082510
b3galt6
UDP-Gal:betaGal beta 1,3-galactosyltransferase polypeptide 6
chr19_-_46018152 1.40 ENSDART00000159206
krit1
KRIT1, ankyrin repeat containing
chr2_-_10877765 1.39 ENSDART00000100607
cdc7
cell division cycle 7 homolog (S. cerevisiae)
chr5_-_67349916 1.37 ENSDART00000144092
mlxip
MLX interacting protein
chr4_-_13931293 1.37 ENSDART00000067172
zcrb1
zinc finger CCHC-type and RNA binding motif 1
chr10_+_10313024 1.37 ENSDART00000142895
ENSDART00000129952
urm1
ubiquitin related modifier 1
chr4_+_17671164 1.34 ENSDART00000040445
gnptab
N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
chr9_+_33158191 1.32 ENSDART00000180786
dopey2
dopey family member 2
chr13_+_24671481 1.31 ENSDART00000001678
adam8a
ADAM metallopeptidase domain 8a
chr4_+_25912308 1.31 ENSDART00000167845
ENSDART00000136927
vezt
vezatin, adherens junctions transmembrane protein
chr19_-_34063567 1.30 ENSDART00000157815
ENSDART00000183907
elmo1
engulfment and cell motility 1 (ced-12 homolog, C. elegans)
chr20_+_46741074 1.30 ENSDART00000145294
si:ch211-57i17.1
si:ch211-57i17.1
chr13_+_25199849 1.29 ENSDART00000139209
ENSDART00000130876
ap3m1
adaptor-related protein complex 3, mu 1 subunit
chr3_-_25377163 1.29 ENSDART00000055490
kpna2
karyopherin alpha 2 (RAG cohort 1, importin alpha 1)
chr10_-_16868211 1.28 ENSDART00000171755
stoml2
stomatin (EPB72)-like 2
chr19_-_11208782 1.25 ENSDART00000044426
ENSDART00000189754
si:dkey-240h12.4
si:dkey-240h12.4
chr8_+_28358161 1.24 ENSDART00000062682
adipor1b
adiponectin receptor 1b
chr14_+_45028062 1.24 ENSDART00000184717
ENSDART00000185481
ATP8A1
ATPase phospholipid transporting 8A1
chr5_+_6672870 1.23 ENSDART00000126598
pxna
paxillin a
chr3_+_60828813 1.23 ENSDART00000128260
CABZ01087514.1

chr16_+_22345513 1.21 ENSDART00000078000
zgc:123238
zgc:123238
chr2_+_34967022 1.21 ENSDART00000134926
astn1
astrotactin 1
chr19_-_8798178 1.21 ENSDART00000188232
cers2a
ceramide synthase 2a
chr10_-_14943281 1.21 ENSDART00000143608
smad2
SMAD family member 2
chr16_+_26747766 1.21 ENSDART00000183257
rad54b
RAD54 homolog B (S. cerevisiae)
chr4_+_13931578 1.20 ENSDART00000142466
pphln1
periphilin 1
chr16_-_4610255 1.20 ENSDART00000081852
ENSDART00000123253
ENSDART00000127554
ENSDART00000029485
arnt
aryl hydrocarbon receptor nuclear translocator
chr13_+_25200105 1.20 ENSDART00000039640
ap3m1
adaptor-related protein complex 3, mu 1 subunit
chr19_+_32401278 1.19 ENSDART00000184353
atxn1a
ataxin 1a
chr9_+_33220342 1.19 ENSDART00000100893
ENSDART00000113451
si:ch211-125e6.13
si:ch211-125e6.13
chr3_-_5228841 1.18 ENSDART00000092373
ENSDART00000182438
myh9b
myosin, heavy chain 9b, non-muscle
chr11_-_26832685 1.13 ENSDART00000153519
iqsec1b
IQ motif and Sec7 domain 1b
chr1_-_29061285 1.12 ENSDART00000053933
ENSDART00000142350
ENSDART00000192615
gemin8
gem (nuclear organelle) associated protein 8
chr23_-_20051369 1.11 ENSDART00000049836
bgnb
biglycan b
chr12_+_2995887 1.11 ENSDART00000189499
ENSDART00000182597
ENSDART00000184918
ENSDART00000182292
lrrc45
leucine rich repeat containing 45
chr10_+_20392083 1.10 ENSDART00000166867
r3hcc1
R3H domain and coiled-coil containing 1
chr1_+_22654875 1.09 ENSDART00000019698
ENSDART00000161874
anxa5b
annexin A5b
chr7_-_25133783 1.09 ENSDART00000173781
ENSDART00000121943
ENSDART00000077219
badb
BCL2 associated agonist of cell death b
chr2_-_57837838 1.08 ENSDART00000010699
sf3a2
splicing factor 3a, subunit 2
chr18_+_6641542 1.07 ENSDART00000160379
c2cd5
C2 calcium-dependent domain containing 5
chr11_-_25461336 1.06 ENSDART00000014945
hcfc1a
host cell factor C1a
chr2_-_39558643 1.05 ENSDART00000139860
ENSDART00000145231
ENSDART00000141721
cbln7
cerebellin 7
chr14_-_7045009 1.05 ENSDART00000112082
rufy1
RUN and FYVE domain containing 1
chr15_-_34408777 1.05 ENSDART00000139934
agmo
alkylglycerol monooxygenase
chr14_+_30413758 1.04 ENSDART00000092953
cnot7
CCR4-NOT transcription complex, subunit 7
chr16_+_1100559 1.04 ENSDART00000092657
adamts16
ADAM metallopeptidase with thrombospondin type 1 motif, 16
chr21_-_11970199 1.04 ENSDART00000114524
nop56
NOP56 ribonucleoprotein homolog
chr20_+_35247410 1.04 ENSDART00000153098
ENSDART00000182470
fbxo16
F-box protein 16
chr1_-_51038885 1.03 ENSDART00000035150
spast
spastin
chr15_+_47362728 1.03 ENSDART00000180712
CABZ01099833.1

chr3_+_22036113 1.02 ENSDART00000132190
cdc27
cell division cycle 27
chr1_+_35956435 1.02 ENSDART00000085021
ENSDART00000148505
mmaa
methylmalonic aciduria (cobalamin deficiency) cblA type
chr9_+_34380299 1.01 ENSDART00000131705
lamp1
lysosomal-associated membrane protein 1
chr10_+_15967643 1.00 ENSDART00000136709
apbb1
amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
chr21_-_3606539 1.00 ENSDART00000062418
dym
dymeclin
chr23_-_37291793 1.00 ENSDART00000083281
ENSDART00000187108
mul1b
mitochondrial E3 ubiquitin protein ligase 1b
chr5_-_67365750 0.98 ENSDART00000062359
unga
uracil DNA glycosylase a
chr15_-_33807758 0.98 ENSDART00000158445
pds5b
PDS5 cohesin associated factor B
chr22_+_12366516 0.98 ENSDART00000157802
r3hdm1
R3H domain containing 1
chr12_-_17593030 0.97 ENSDART00000168758
usp42
ubiquitin specific peptidase 42
chr6_-_33871055 0.95 ENSDART00000115409
mast2
microtubule associated serine/threonine kinase 2
chr7_+_48297842 0.94 ENSDART00000052123
slc25a44b
solute carrier family 25, member 44 b
chr24_-_20152965 0.93 ENSDART00000147004
oxsr1b
oxidative stress responsive 1b
chr14_-_36763302 0.93 ENSDART00000074786
ctso
cathepsin O
chr4_+_13931733 0.93 ENSDART00000141742
ENSDART00000067175
pphln1
periphilin 1
chr13_-_17943135 0.91 ENSDART00000176027
march8
membrane-associated ring finger (C3HC4) 8
chr1_+_14020445 0.91 ENSDART00000079716
hpf1
histone PARylation factor 1
chr12_-_33659328 0.91 ENSDART00000153457
tmem94
transmembrane protein 94
chr16_+_32014552 0.91 ENSDART00000047570
mboat7
membrane bound O-acyltransferase domain containing 7
chr5_-_67365333 0.87 ENSDART00000133438
unga
uracil DNA glycosylase a
chr23_+_32101202 0.85 ENSDART00000000992
zgc:56699
zgc:56699
chr25_-_13549577 0.85 ENSDART00000166772
ano10b
anoctamin 10b
chr3_+_42999277 0.85 ENSDART00000163595
ints1
integrator complex subunit 1
chr8_+_9715010 0.85 ENSDART00000139414
gripap1
GRIP1 associated protein 1
chr22_-_3275888 0.84 ENSDART00000164743
si:zfos-943e10.1
si:zfos-943e10.1
chr3_+_15893039 0.83 ENSDART00000055780
jpt2
Jupiter microtubule associated homolog 2
chr18_-_16885362 0.83 ENSDART00000132778
swap70b
switching B cell complex subunit SWAP70b
chr6_-_3998199 0.82 ENSDART00000059212
unc50
unc-50 homolog (C. elegans)
chr25_-_21031007 0.81 ENSDART00000138985
gnaia
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide a
chr13_+_18371208 0.80 ENSDART00000138172
ccar1
cell division cycle and apoptosis regulator 1
chr2_-_50272077 0.79 ENSDART00000127623
cul1a
cullin 1a
chr19_-_24267823 0.79 ENSDART00000132430
s100v2
S100 calcium binding protein V2
chr23_-_32100106 0.78 ENSDART00000044658
letmd1
LETM1 domain containing 1
chr4_-_5019113 0.78 ENSDART00000189321
ENSDART00000081990
strip2
striatin interacting protein 2
chr9_+_2574122 0.78 ENSDART00000166326
ENSDART00000191822
CIR1
si:ch73-167c12.2
chr7_-_7692723 0.76 ENSDART00000183352
aadat
aminoadipate aminotransferase
chr24_-_36187094 0.76 ENSDART00000111891
esco1
establishment of sister chromatid cohesion N-acetyltransferase 1
chr5_-_33039670 0.76 ENSDART00000141361
glipr2
GLI pathogenesis-related 2
chr6_+_40951227 0.76 ENSDART00000156660
patz1
POZ (BTB) and AT hook containing zinc finger 1
chr3_-_52899394 0.75 ENSDART00000128223
CHCHD5
coiled-coil-helix-coiled-coil-helix domain containing 5
chr11_+_31323746 0.75 ENSDART00000180220
ENSDART00000189937
sipa1l2
signal-induced proliferation-associated 1 like 2
chr3_+_46271911 0.74 ENSDART00000186557
ENSDART00000113531
mkl2b
MKL/myocardin-like 2b
chr7_-_7692992 0.74 ENSDART00000192619
aadat
aminoadipate aminotransferase
chr5_+_66250856 0.74 ENSDART00000132789
secisbp2
SECIS binding protein 2
chr9_+_38502524 0.74 ENSDART00000087229
lmln
leishmanolysin-like (metallopeptidase M8 family)
chr14_+_3507326 0.74 ENSDART00000159326
gstp1
glutathione S-transferase pi 1
chr2_-_22530969 0.74 ENSDART00000159641
znf644a
zinc finger protein 644a
chr10_-_31104983 0.74 ENSDART00000186941
pknox2
pbx/knotted 1 homeobox 2
chr6_-_3978919 0.73 ENSDART00000167753
slc25a12
solute carrier family 25 (aspartate/glutamate carrier), member 12
chr20_+_54383838 0.72 ENSDART00000157737
lrfn5b
leucine rich repeat and fibronectin type III domain containing 5b
chr20_+_22799641 0.72 ENSDART00000131132
scfd2
sec1 family domain containing 2
chr7_+_1530024 0.71 ENSDART00000163082
tox4b
TOX high mobility group box family member 4 b
chr23_+_4777348 0.71 ENSDART00000171971
vgll4a
vestigial-like family member 4a
chr12_-_17199381 0.71 ENSDART00000193292
lipf
lipase, gastric
chr13_+_5978809 0.70 ENSDART00000102563
ENSDART00000121598
phf10
PHD finger protein 10
chr3_+_17634952 0.70 ENSDART00000191833
rab5c
RAB5C, member RAS oncogene family
chr7_+_16047863 0.69 ENSDART00000188750
immp1l
inner mitochondrial membrane peptidase subunit 1
chr6_-_16394528 0.68 ENSDART00000089445
agap1
ArfGAP with GTPase domain, ankyrin repeat and PH domain 1
chr20_-_27190393 0.68 ENSDART00000149024
btbd7
BTB (POZ) domain containing 7
chr6_-_55309190 0.67 ENSDART00000162117
ube2c
ubiquitin-conjugating enzyme E2C
chr6_-_57485411 0.67 ENSDART00000011663
snrpb
small nuclear ribonucleoprotein polypeptides B and B1
chr15_+_39096736 0.67 ENSDART00000129511
ENSDART00000014877
robo2
roundabout, axon guidance receptor, homolog 2 (Drosophila)
chr6_+_26948093 0.66 ENSDART00000153595
farp2
FERM, RhoGEF and pleckstrin domain protein 2
chr13_+_31550185 0.66 ENSDART00000127843
ppm1aa
protein phosphatase, Mg2+/Mn2+ dependent, 1Aa
chr10_-_2522588 0.66 ENSDART00000081926
CU856539.1

chr3_-_13509283 0.66 ENSDART00000166832
slc25a19
solute carrier family 25 (mitochondrial thiamine pyrophosphate carrier), member 19
chr20_-_894374 0.66 ENSDART00000104725
ENSDART00000142361
snx14
sorting nexin 14
chr2_+_10878406 0.65 ENSDART00000091497
tceanc2
transcription elongation factor A (SII) N-terminal and central domain containing 2
chr8_+_48965767 0.65 ENSDART00000008058
aak1a
AP2 associated kinase 1a
chr22_+_1170294 0.65 ENSDART00000159761
ENSDART00000169809
irf6
interferon regulatory factor 6
chr12_+_25223843 0.65 ENSDART00000077180
ENSDART00000127454
ENSDART00000122665
mta3
metastasis associated 1 family, member 3
chr12_-_34258384 0.65 ENSDART00000109196
pgs1
phosphatidylglycerophosphate synthase 1
chr11_+_31324335 0.64 ENSDART00000088093
sipa1l2
signal-induced proliferation-associated 1 like 2
chr23_+_4777612 0.64 ENSDART00000135933
vgll4a
vestigial-like family member 4a
chr17_+_24222190 0.64 ENSDART00000181698
ENSDART00000189411
ehbp1
EH domain binding protein 1
chr25_-_34973211 0.64 ENSDART00000045177
cdk10
cyclin-dependent kinase 10
chr16_-_36979592 0.63 ENSDART00000168443
snrnp48
small nuclear ribonucleoprotein 48 (U11/U12)
chr23_+_38976201 0.62 ENSDART00000188090
ATP9A
ATPase phospholipid transporting 9A (putative)
chr14_-_47391084 0.62 ENSDART00000159608
fstl5
follistatin-like 5
chr13_-_41546779 0.62 ENSDART00000163331
pcdh15a
protocadherin-related 15a
chr20_-_8024582 0.62 ENSDART00000083898
plpp3
phospholipid phosphatase 3
chr17_-_33412868 0.62 ENSDART00000187521
BX323819.1

chr20_+_18943406 0.60 ENSDART00000193590
mtmr9
myotubularin related protein 9

Network of associatons between targets according to the STRING database.

First level regulatory network of arid3a+arid3b+arid3c

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 4.5 GO:1900145 nodal signaling pathway involved in determination of left/right asymmetry(GO:0038107) regulation of nodal signaling pathway involved in determination of left/right asymmetry(GO:1900145)
0.6 1.9 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.6 2.4 GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518)
0.5 4.3 GO:1901339 regulation of store-operated calcium channel activity(GO:1901339)
0.5 1.4 GO:0045601 negative regulation of epithelial cell differentiation(GO:0030857) regulation of endothelial cell differentiation(GO:0045601)
0.5 2.8 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.4 1.3 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.4 2.1 GO:0097355 protein localization to heterochromatin(GO:0097355)
0.4 3.3 GO:0070933 histone H4 deacetylation(GO:0070933)
0.4 7.2 GO:2000401 regulation of lymphocyte migration(GO:2000401)
0.4 1.5 GO:0040016 embryonic cleavage(GO:0040016)
0.4 1.9 GO:0097510 base-excision repair, AP site formation via deaminated base removal(GO:0097510)
0.4 1.5 GO:0036462 TRAIL-activated apoptotic signaling pathway(GO:0036462)
0.3 1.0 GO:0051230 protein hexamerization(GO:0034214) mitotic spindle disassembly(GO:0051228) spindle disassembly(GO:0051230)
0.3 1.8 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.3 2.0 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.3 1.7 GO:0090133 establishment or maintenance of cytoskeleton polarity(GO:0030952) mesendoderm migration(GO:0090133) cell migration involved in mesendoderm migration(GO:0090134)
0.3 0.8 GO:0034421 post-translational protein acetylation(GO:0034421)
0.2 0.7 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.2 2.6 GO:0045453 bone resorption(GO:0045453)
0.2 0.9 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.2 1.4 GO:0032447 protein urmylation(GO:0032447)
0.2 3.4 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.2 0.9 GO:0036149 phosphatidylinositol acyl-chain remodeling(GO:0036149)
0.2 0.7 GO:0015695 organic cation transport(GO:0015695)
0.2 2.4 GO:0000022 mitotic spindle elongation(GO:0000022) spindle elongation(GO:0051231) mitotic spindle midzone assembly(GO:0051256)
0.2 0.6 GO:0006655 phosphatidylglycerol biosynthetic process(GO:0006655) cardiolipin biosynthetic process(GO:0032049)
0.2 1.1 GO:0010828 positive regulation of glucose transport(GO:0010828)
0.2 0.8 GO:0099563 modification of synaptic structure(GO:0099563)
0.2 1.0 GO:0046485 ether lipid metabolic process(GO:0046485)
0.2 1.2 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.2 0.6 GO:0048205 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.2 1.2 GO:0070650 actin filament bundle distribution(GO:0070650)
0.2 1.0 GO:0032655 interleukin-12 production(GO:0032615) regulation of interleukin-12 production(GO:0032655)
0.2 1.9 GO:0046835 carbohydrate phosphorylation(GO:0046835)
0.2 2.8 GO:0016486 peptide hormone processing(GO:0016486)
0.2 0.9 GO:0060049 regulation of protein glycosylation(GO:0060049)
0.2 2.5 GO:0098927 early endosome to late endosome transport(GO:0045022) vesicle-mediated transport between endosomal compartments(GO:0098927)
0.2 1.7 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.1 0.6 GO:0048308 organelle inheritance(GO:0048308) Golgi inheritance(GO:0048313)
0.1 0.4 GO:0015808 L-alanine transport(GO:0015808) proline transport(GO:0015824)
0.1 0.8 GO:0048714 positive regulation of gliogenesis(GO:0014015) positive regulation of glial cell differentiation(GO:0045687) positive regulation of oligodendrocyte differentiation(GO:0048714)
0.1 1.5 GO:0070301 cellular response to hydrogen peroxide(GO:0070301)
0.1 0.5 GO:0070272 proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.1 0.6 GO:0016572 histone phosphorylation(GO:0016572)
0.1 1.2 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.1 1.1 GO:0050819 negative regulation of coagulation(GO:0050819)
0.1 0.4 GO:0060829 negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060829)
0.1 1.3 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.1 0.3 GO:0071514 genetic imprinting(GO:0071514)
0.1 0.5 GO:0071423 thiosulfate transport(GO:0015709) oxaloacetate transport(GO:0015729) malate transport(GO:0015743) succinate transport(GO:0015744) succinate transmembrane transport(GO:0071422) malate transmembrane transport(GO:0071423)
0.1 1.1 GO:0071479 cellular response to ionizing radiation(GO:0071479)
0.1 0.3 GO:0031087 nuclear-transcribed mRNA catabolic process, deadenylation-independent decay(GO:0031086) deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.1 0.7 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.1 0.5 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.1 1.0 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.1 0.6 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.1 0.3 GO:0033512 L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512)
0.1 1.0 GO:1902101 positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.1 6.9 GO:0030203 glycosaminoglycan metabolic process(GO:0030203)
0.1 1.2 GO:0061055 myotome development(GO:0061055)
0.1 1.4 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.1 1.6 GO:0098703 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.1 0.3 GO:0072045 convergent extension involved in nephron morphogenesis(GO:0072045)
0.1 0.5 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.1 0.4 GO:1904036 negative regulation of epithelial cell apoptotic process(GO:1904036)
0.1 0.7 GO:0015800 acidic amino acid transport(GO:0015800) aspartate transport(GO:0015810) L-glutamate transport(GO:0015813) malate-aspartate shuttle(GO:0043490)
0.1 0.6 GO:0045719 negative regulation of peptidyl-serine phosphorylation(GO:0033137) negative regulation of glycogen biosynthetic process(GO:0045719) negative regulation of glycogen metabolic process(GO:0070874)
0.1 0.7 GO:0050975 sensory perception of touch(GO:0050975)
0.1 0.4 GO:0051561 positive regulation of mitochondrial calcium ion concentration(GO:0051561)
0.1 0.7 GO:0031579 membrane raft organization(GO:0031579)
0.1 1.5 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.1 1.5 GO:0006515 misfolded or incompletely synthesized protein catabolic process(GO:0006515)
0.1 0.4 GO:1904396 regulation of neuromuscular junction development(GO:1904396)
0.1 5.1 GO:0032272 negative regulation of actin filament polymerization(GO:0030837) negative regulation of protein polymerization(GO:0032272)
0.1 0.6 GO:0006611 protein export from nucleus(GO:0006611)
0.1 0.2 GO:1901890 positive regulation of cell junction assembly(GO:1901890)
0.1 0.8 GO:0055117 regulation of cardiac muscle contraction(GO:0055117)
0.0 0.8 GO:0050910 detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.0 0.3 GO:2000580 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 0.4 GO:0048730 epidermis morphogenesis(GO:0048730)
0.0 0.3 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.0 0.5 GO:0019730 antimicrobial humoral response(GO:0019730)
0.0 0.3 GO:0045299 otolith mineralization(GO:0045299)
0.0 2.4 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.0 0.7 GO:0021680 cerebellar Purkinje cell layer development(GO:0021680)
0.0 1.8 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.8 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.0 0.7 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.0 1.0 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 1.1 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 0.3 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.0 1.2 GO:0009636 response to toxic substance(GO:0009636)
0.0 0.6 GO:0098962 regulation of postsynaptic neurotransmitter receptor activity(GO:0098962)
0.0 0.3 GO:0006857 oligopeptide transport(GO:0006857)
0.0 1.1 GO:0072310 glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310)
0.0 0.7 GO:0048885 neuromast deposition(GO:0048885)
0.0 0.6 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.3 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.0 0.2 GO:1902514 calcium ion transmembrane transport via high voltage-gated calcium channel(GO:0061577) regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1902514)
0.0 0.4 GO:0051967 negative regulation of cytosolic calcium ion concentration(GO:0051481) negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 0.8 GO:0038061 NIK/NF-kappaB signaling(GO:0038061)
0.0 0.7 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0 0.1 GO:0021611 facial nerve formation(GO:0021611)
0.0 1.1 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.2 GO:0051043 regulation of membrane protein ectodomain proteolysis(GO:0051043) negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0 0.5 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.0 0.6 GO:0010507 negative regulation of autophagy(GO:0010507)
0.0 0.5 GO:0060021 palate development(GO:0060021)
0.0 1.8 GO:0030100 regulation of endocytosis(GO:0030100)
0.0 0.1 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.0 1.5 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.0 0.1 GO:0006013 mannose metabolic process(GO:0006013)
0.0 1.5 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.0 0.7 GO:0061138 morphogenesis of a branching epithelium(GO:0061138)
0.0 0.7 GO:0060219 camera-type eye photoreceptor cell differentiation(GO:0060219)
0.0 1.1 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.0 2.1 GO:0016573 histone acetylation(GO:0016573)
0.0 0.4 GO:0003094 glomerular filtration(GO:0003094)
0.0 0.2 GO:0006777 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.0 0.6 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 1.3 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.0 0.2 GO:0034724 DNA replication-independent nucleosome organization(GO:0034724)
0.0 0.8 GO:0061386 closure of optic fissure(GO:0061386)
0.0 0.7 GO:0006749 glutathione metabolic process(GO:0006749)
0.0 0.3 GO:0008354 germ cell migration(GO:0008354)
0.0 0.3 GO:1901663 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 1.8 GO:0032147 activation of protein kinase activity(GO:0032147)
0.0 0.3 GO:0048702 embryonic neurocranium morphogenesis(GO:0048702)
0.0 1.6 GO:1903706 regulation of hemopoiesis(GO:1903706)
0.0 0.7 GO:0045766 positive regulation of angiogenesis(GO:0045766)
0.0 0.3 GO:0042219 cellular modified amino acid catabolic process(GO:0042219)
0.0 0.2 GO:0006991 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.0 0.1 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.2 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.0 0.6 GO:0016575 histone deacetylation(GO:0016575)
0.0 1.7 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 0.1 GO:0031295 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.0 0.1 GO:0050732 negative regulation of peptidyl-tyrosine phosphorylation(GO:0050732) negative regulation of protein tyrosine kinase activity(GO:0061099)
0.0 0.3 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 0.3 GO:0060037 pharyngeal system development(GO:0060037)
0.0 2.5 GO:0007265 Ras protein signal transduction(GO:0007265)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0098536 deuterosome(GO:0098536)
0.5 3.4 GO:0000439 core TFIIH complex(GO:0000439)
0.4 1.3 GO:0071065 alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065)
0.4 2.5 GO:0070695 FHF complex(GO:0070695)
0.4 2.2 GO:0071012 U2-type catalytic step 1 spliceosome(GO:0071006) catalytic step 1 spliceosome(GO:0071012)
0.3 1.4 GO:0008091 spectrin(GO:0008091)
0.2 0.9 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.2 1.5 GO:0032797 SMN complex(GO:0032797)
0.2 2.4 GO:1990023 mitotic spindle midzone(GO:1990023)
0.2 0.7 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.2 1.0 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.2 2.5 GO:0071564 npBAF complex(GO:0071564)
0.1 1.3 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.1 0.8 GO:0098837 postsynaptic recycling endosome(GO:0098837)
0.1 1.9 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 0.7 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.1 1.1 GO:0035145 exon-exon junction complex(GO:0035145)
0.1 0.7 GO:0005687 U4 snRNP(GO:0005687)
0.1 3.1 GO:0030014 CCR4-NOT complex(GO:0030014)
0.1 0.6 GO:0031501 mannosyltransferase complex(GO:0031501)
0.1 1.1 GO:0005686 U2 snRNP(GO:0005686)
0.1 3.6 GO:0055038 recycling endosome membrane(GO:0055038)
0.1 2.5 GO:0030131 clathrin adaptor complex(GO:0030131)
0.1 1.2 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.1 1.9 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.1 0.5 GO:0019008 molybdopterin synthase complex(GO:0019008)
0.1 0.5 GO:0000974 Prp19 complex(GO:0000974)
0.1 1.7 GO:0031932 TORC2 complex(GO:0031932)
0.1 0.3 GO:0071439 clathrin complex(GO:0071439)
0.1 1.2 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.1 1.8 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 3.0 GO:0016592 mediator complex(GO:0016592)
0.1 0.7 GO:0016328 lateral plasma membrane(GO:0016328)
0.1 0.5 GO:0071797 LUBAC complex(GO:0071797)
0.1 1.1 GO:0044665 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 3.9 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 3.6 GO:0030173 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.0 0.8 GO:0032039 integrator complex(GO:0032039)
0.0 0.2 GO:0016600 flotillin complex(GO:0016600)
0.0 1.0 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 10.3 GO:0005764 lysosome(GO:0005764)
0.0 0.3 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.0 0.4 GO:1990246 uniplex complex(GO:1990246)
0.0 0.6 GO:0032420 stereocilium(GO:0032420)
0.0 0.3 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.0 2.1 GO:0042383 sarcolemma(GO:0042383)
0.0 2.1 GO:0000123 histone acetyltransferase complex(GO:0000123)
0.0 2.3 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.4 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.0 0.5 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.9 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.0 1.4 GO:0005871 kinesin complex(GO:0005871)
0.0 1.3 GO:0005814 centriole(GO:0005814)
0.0 0.2 GO:0035101 FACT complex(GO:0035101)
0.0 0.7 GO:0030139 endocytic vesicle(GO:0030139)
0.0 0.2 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.6 GO:0098978 glutamatergic synapse(GO:0098978)
0.0 0.1 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.6 GO:0031941 filamentous actin(GO:0031941)
0.0 0.6 GO:0005643 nuclear pore(GO:0005643)
0.0 1.2 GO:0005925 focal adhesion(GO:0005925)
0.0 1.0 GO:0031965 nuclear membrane(GO:0031965)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.9 GO:0043739 G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739)
0.5 7.8 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.3 2.6 GO:0003993 acid phosphatase activity(GO:0003993)
0.3 1.4 GO:0001223 transcription coactivator binding(GO:0001223)
0.3 1.0 GO:0048487 beta-tubulin binding(GO:0048487)
0.2 3.3 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.2 1.5 GO:0036137 kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.2 1.2 GO:0015616 DNA translocase activity(GO:0015616)
0.2 0.5 GO:0004061 arylformamidase activity(GO:0004061)
0.2 2.5 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.2 1.5 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.2 0.5 GO:0042806 fucose binding(GO:0042806)
0.1 1.3 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.1 0.5 GO:0071253 connexin binding(GO:0071253)
0.1 1.6 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.1 0.5 GO:0030366 molybdopterin synthase activity(GO:0030366)
0.1 0.4 GO:0008119 thiopurine S-methyltransferase activity(GO:0008119)
0.1 0.7 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.1 0.7 GO:0045118 azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.1 1.5 GO:0002020 protease binding(GO:0002020)
0.1 0.5 GO:0015140 thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131) malate transmembrane transporter activity(GO:0015140)
0.1 2.5 GO:0016780 phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.1 1.2 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.1 0.6 GO:0016312 inositol bisphosphate phosphatase activity(GO:0016312)
0.1 0.3 GO:0016748 succinyltransferase activity(GO:0016748)
0.1 1.4 GO:0031386 protein tag(GO:0031386)
0.1 0.4 GO:0022858 L-alanine transmembrane transporter activity(GO:0015180) L-proline transmembrane transporter activity(GO:0015193) alanine transmembrane transporter activity(GO:0022858)
0.1 1.2 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.1 0.3 GO:0008169 C-methyltransferase activity(GO:0008169)
0.1 1.3 GO:0061608 nuclear import signal receptor activity(GO:0061608)
0.1 0.7 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.1 1.0 GO:0035250 UDP-galactosyltransferase activity(GO:0035250)
0.1 0.6 GO:0004376 glycolipid mannosyltransferase activity(GO:0004376)
0.1 1.0 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.1 2.6 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.1 2.2 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 1.5 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.1 1.2 GO:0070411 I-SMAD binding(GO:0070411)
0.1 0.6 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.1 0.8 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.1 0.5 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.1 0.7 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.1 0.2 GO:2001070 starch binding(GO:2001070)
0.0 0.4 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.3 GO:0032051 clathrin light chain binding(GO:0032051)
0.0 6.5 GO:0042803 protein homodimerization activity(GO:0042803)
0.0 3.1 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 0.7 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 1.4 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.9 GO:0071617 lysophospholipid acyltransferase activity(GO:0071617)
0.0 1.0 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 2.8 GO:0030674 protein binding, bridging(GO:0030674)
0.0 1.0 GO:0097472 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.0 0.8 GO:0030515 snoRNA binding(GO:0030515)
0.0 0.3 GO:0042936 dipeptide transporter activity(GO:0042936) dipeptide transmembrane transporter activity(GO:0071916)
0.0 0.3 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 0.1 GO:0030251 cyclase inhibitor activity(GO:0010852) guanylate cyclase inhibitor activity(GO:0030251)
0.0 0.3 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.0 0.5 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.2 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.0 1.6 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.9 GO:0042287 MHC protein binding(GO:0042287)
0.0 1.5 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.8 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.9 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.4 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 1.3 GO:0031625 ubiquitin protein ligase binding(GO:0031625) ubiquitin-like protein ligase binding(GO:0044389)
0.0 1.3 GO:0017022 myosin binding(GO:0017022)
0.0 0.4 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.0 0.6 GO:0052744 phosphatidylinositol-3-phosphatase activity(GO:0004438) phosphatidylinositol monophosphate phosphatase activity(GO:0052744)
0.0 0.6 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.9 GO:0005347 ATP transmembrane transporter activity(GO:0005347)
0.0 0.6 GO:0042577 lipid phosphatase activity(GO:0042577)
0.0 0.8 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 4.2 GO:0005125 cytokine activity(GO:0005125)
0.0 1.3 GO:0017124 SH3 domain binding(GO:0017124)
0.0 4.9 GO:0017171 serine-type peptidase activity(GO:0008236) serine hydrolase activity(GO:0017171)
0.0 1.5 GO:0043021 ribonucleoprotein complex binding(GO:0043021)
0.0 0.2 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.3 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.0 0.7 GO:0030145 manganese ion binding(GO:0030145)
0.0 0.5 GO:0051018 protein kinase A binding(GO:0051018)
0.0 1.3 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 2.5 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.8 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.1 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 1.8 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 3.9 GO:0008017 microtubule binding(GO:0008017)
0.0 1.7 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.1 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.0 0.5 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 1.8 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.1 GO:0004488 methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NADP+) activity(GO:0004488)
0.0 0.4 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.3 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.8 PID IL5 PATHWAY IL5-mediated signaling events
0.2 2.5 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1 1.2 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.1 2.1 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.1 1.7 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.1 1.3 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.7 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 0.4 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 3.3 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 0.4 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 1.4 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 4.3 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.5 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 4.2 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 1.0 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.4 PID RHOA REG PATHWAY Regulation of RhoA activity

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 4.0 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.3 2.8 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.2 0.9 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.2 2.0 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.1 6.3 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.1 2.3 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.1 3.4 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.1 1.7 REACTOME CD28 DEPENDENT PI3K AKT SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.1 1.4 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.1 3.5 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.1 1.2 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.1 1.7 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.1 0.7 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1 1.0 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.1 0.7 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.1 0.3 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.1 0.7 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 1.3 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0 0.5 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.4 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.0 1.4 REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX Genes involved in Activation of the pre-replicative complex
0.0 1.9 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.6 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.7 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.7 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.4 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.0 1.3 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 0.4 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.0 0.1 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.7 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.4 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.9 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 0.7 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.2 REACTOME FORMATION OF RNA POL II ELONGATION COMPLEX Genes involved in Formation of RNA Pol II elongation complex
0.0 0.3 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 1.0 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis
0.0 0.1 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis