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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for arid5a+arid6

Z-value: 0.44

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Transcription factors associated with arid5a+arid6

Gene Symbol Gene ID Gene Info
arid6
ENSDARG00000069988 AT-rich interaction domain 6
arid5a
ENSDARG00000077120 AT rich interactive domain 5A (MRF1-like)

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
arid6dr11_v1_chr21_+_11244068_11244068-0.474.8e-02Click!
arid5adr11_v1_chr8_+_52377516_52377516-0.048.7e-01Click!

Activity profile of arid5a+arid6 motif

Sorted Z-values of arid5a+arid6 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr22_+_25753972 1.22 ENSDART00000188417
AL929192.2

chr3_+_39566999 0.87 ENSDART00000146867
aldoaa
aldolase a, fructose-bisphosphate, a
chr22_+_25704430 0.78 ENSDART00000143776
si:dkeyp-98a7.3
si:dkeyp-98a7.3
chr20_+_54024559 0.74 ENSDART00000130767
si:dkey-241l7.4
si:dkey-241l7.4
chr22_+_25715925 0.73 ENSDART00000150650
si:dkeyp-98a7.7
si:dkeyp-98a7.7
chr22_+_25687525 0.70 ENSDART00000135717
si:dkeyp-98a7.3
si:dkeyp-98a7.3
chr22_+_25681911 0.69 ENSDART00000113381
si:dkeyp-98a7.3
si:dkeyp-98a7.3
chr22_+_25693295 0.69 ENSDART00000123888
ENSDART00000150783
si:dkeyp-98a7.4
si:dkeyp-98a7.3
si:dkeyp-98a7.4
si:dkeyp-98a7.3
chr19_-_1948236 0.68 ENSDART00000163344
znrf2a
zinc and ring finger 2a
chr21_-_2299002 0.61 ENSDART00000168712
si:ch73-299h12.6
si:ch73-299h12.6
chr5_+_25074648 0.52 ENSDART00000188951
mrpl41
mitochondrial ribosomal protein L41
chr10_+_44699734 0.51 ENSDART00000167952
ENSDART00000158681
ENSDART00000190188
ENSDART00000168276
scarb1
scavenger receptor class B, member 1
chr5_-_2721686 0.50 ENSDART00000169404
hspa5
heat shock protein 5
chr9_+_41040294 0.48 ENSDART00000000693
osgepl1
O-sialoglycoprotein endopeptidase-like 1
chr4_-_8043839 0.48 ENSDART00000190047
ENSDART00000057567
si:ch211-240l19.5
si:ch211-240l19.5
chr2_+_54389750 0.47 ENSDART00000189236
rab12
RAB12, member RAS oncogene family
chr22_-_557965 0.47 ENSDART00000001201
bysl
bystin-like
chr16_-_48400639 0.47 ENSDART00000159372
eif3ha
eukaryotic translation initiation factor 3, subunit H, a
chr24_+_7322116 0.45 ENSDART00000005804
XRCC2
X-ray repair cross complementing 2
chr6_+_52235441 0.45 ENSDART00000056319
cox6c
cytochrome c oxidase subunit VIc
chr11_-_11331052 0.44 ENSDART00000081765
ENSDART00000160247
mrpl4
mitochondrial ribosomal protein L4
chr3_+_24207243 0.44 ENSDART00000023454
ENSDART00000136400
adsl
adenylosuccinate lyase
chr1_+_16073887 0.44 ENSDART00000160270
tusc3
tumor suppressor candidate 3
chr22_-_18491813 0.43 ENSDART00000105419
si:ch211-212d10.2
si:ch211-212d10.2
chr19_-_1947403 0.42 ENSDART00000113951
ENSDART00000151293
ENSDART00000134074
znrf2a
zinc and ring finger 2a
chr10_+_39091353 0.41 ENSDART00000125986
si:ch73-1a9.4
si:ch73-1a9.4
chr10_-_17222083 0.41 ENSDART00000134059
depdc5
DEP domain containing 5
chr20_+_36628059 0.41 ENSDART00000062898
ephx1
epoxide hydrolase 1, microsomal (xenobiotic)
chr6_+_13787855 0.39 ENSDART00000182899
tmem198b
transmembrane protein 198b
chr19_+_11978209 0.38 ENSDART00000111568
polr2k
polymerase (RNA) II (DNA directed) polypeptide K
chr18_+_19456648 0.38 ENSDART00000079695
zwilch
zwilch kinetochore protein
chr19_+_816208 0.36 ENSDART00000093304
nrm
nurim
chr3_-_55104310 0.36 ENSDART00000101713
hbba1
hemoglobin, beta adult 1
chr12_+_48220584 0.36 ENSDART00000164392
lrrc20
leucine rich repeat containing 20
chr21_-_3422635 0.36 ENSDART00000150975
smad7
SMAD family member 7
chr22_+_15343953 0.35 ENSDART00000045682
rrp36
ribosomal RNA processing 36
chr3_+_31039923 0.35 ENSDART00000147706
cox6a2
cytochrome c oxidase subunit VIa polypeptide 2
chr18_-_19456269 0.34 ENSDART00000060363
rpl4
ribosomal protein L4
chr24_+_26328787 0.34 ENSDART00000003884
mynn
myoneurin
chr1_+_53714734 0.33 ENSDART00000114689
pus10
pseudouridylate synthase 10
chr20_+_14114258 0.33 ENSDART00000044937
kcns3b
potassium voltage-gated channel, delayed-rectifier, subfamily S, member 3b
chr1_-_54063520 0.33 ENSDART00000171722
smdt1b
single-pass membrane protein with aspartate-rich tail 1b
chr13_-_5064481 0.33 ENSDART00000091806
ENSDART00000032322
abcg2c
ATP-binding cassette, sub-family G (WHITE), member 2c
chr23_-_35483163 0.32 ENSDART00000138660
ENSDART00000113643
ENSDART00000189269
fbxo25
F-box protein 25
chr11_-_438294 0.32 ENSDART00000040812
nuf2
NUF2, NDC80 kinetochore complex component, homolog
chr16_+_9762261 0.32 ENSDART00000020654
psmd4b
proteasome 26S subunit, non-ATPase 4b
chr8_-_53535262 0.32 ENSDART00000167839
ENSDART00000157521
actr8
ARP8 actin related protein 8 homolog
chr25_-_1323623 0.31 ENSDART00000156532
ENSDART00000157163
ENSDART00000156062
ENSDART00000082447
ENSDART00000189175
calml4b
calmodulin-like 4b
chr1_-_53714885 0.30 ENSDART00000026409
cct4
chaperonin containing TCP1, subunit 4 (delta)
chr21_+_45502621 0.30 ENSDART00000166719
si:dkey-223p19.2
si:dkey-223p19.2
chr18_+_7594012 0.30 ENSDART00000062150
zgc:77752
zgc:77752
chr11_-_574423 0.30 ENSDART00000176364
ENSDART00000130504
mkrn2
makorin, ring finger protein, 2
chr7_-_12968689 0.29 ENSDART00000173115
ENSDART00000013690
rplp2l
ribosomal protein, large P2, like
chr16_-_46524842 0.29 ENSDART00000169477
tmem176l.1
transmembrane protein 176l.1
chr22_-_2959005 0.29 ENSDART00000040701
ing5a
inhibitor of growth family, member 5a
chr19_-_41405187 0.29 ENSDART00000038038
ENSDART00000172350
sem1
SEM1, 26S proteasome complex subunit
chr24_-_9991153 0.29 ENSDART00000137794
ENSDART00000106252
ENSDART00000188309
ENSDART00000188266
ENSDART00000188660
ENSDART00000185713
ENSDART00000179773
zgc:152652
zgc:152652
chr8_-_46321889 0.29 ENSDART00000075189
ENSDART00000122801
mtor
mechanistic target of rapamycin kinase
chr19_+_1465004 0.28 ENSDART00000159157
CABZ01073736.1

chr24_-_35561672 0.28 ENSDART00000058564
mcm4
minichromosome maintenance complex component 4
chr25_-_774350 0.28 ENSDART00000166321
ENSDART00000160386
IRAK4
interleukin 1 receptor associated kinase 4
chr11_-_44906703 0.28 ENSDART00000180591
zgc:171772
zgc:171772
chr16_+_52847079 0.28 ENSDART00000163151
cep72
centrosomal protein 72
chr23_+_19670085 0.28 ENSDART00000031872
kctd6b
potassium channel tetramerization domain containing 6b
chr24_-_36271352 0.27 ENSDART00000153682
ENSDART00000155892
si:ch211-40k21.5
si:ch211-40k21.5
chr19_-_1363759 0.27 ENSDART00000166088
zgc:63863
zgc:63863
chr12_-_47648538 0.26 ENSDART00000108477
fh
fumarate hydratase
chr17_-_4395373 0.26 ENSDART00000015923
klhl10a
kelch-like family member 10a
chr21_-_8003782 0.26 ENSDART00000126792
si:dkey-163m14.7
si:dkey-163m14.7
chr9_-_18911608 0.26 ENSDART00000138785
si:dkey-239h2.3
si:dkey-239h2.3
chr5_+_37837245 0.26 ENSDART00000171617
epd
ependymin
chr4_-_72609118 0.26 ENSDART00000174077
si:cabz01054396.2
si:cabz01054396.2
chr4_+_72723304 0.26 ENSDART00000186791
ENSDART00000158902
ENSDART00000191925
rab3ip
RAB3A interacting protein (rabin3)
chr21_+_45502773 0.25 ENSDART00000160059
ENSDART00000165704
si:dkey-223p19.2
si:dkey-223p19.2
chr25_+_34845115 0.25 ENSDART00000061996
tmem231
transmembrane protein 231
chr5_+_4366431 0.25 ENSDART00000168560
ENSDART00000149185
sat1a.2
spermidine/spermine N1-acetyltransferase 1a, duplicate 2
chr15_+_32387063 0.25 ENSDART00000154210
ENSDART00000156525
si:ch211-162k9.5
si:ch211-162k9.5
chr11_-_41853874 0.25 ENSDART00000002556
mrto4
MRT4 homolog, ribosome maturation factor
chr13_-_12021566 0.25 ENSDART00000125430
pprc1
peroxisome proliferator-activated receptor gamma, coactivator-related 1
chr24_-_7632187 0.25 ENSDART00000041714
atp6v0a1b
ATPase H+ transporting V0 subunit a1b
chr23_+_45512825 0.25 ENSDART00000064846
prelid1b
PRELI domain containing 1b
chr22_-_15562933 0.24 ENSDART00000141528
ankmy1
ankyrin repeat and MYND domain containing 1
chr5_+_22177033 0.24 ENSDART00000131223
fdx1b
ferredoxin 1b
chr2_-_3611960 0.24 ENSDART00000184579
pter
phosphotriesterase related
chr21_+_10577527 0.24 ENSDART00000165070
ENSDART00000127963
ccbe1
collagen and calcium binding EGF domains 1
chr25_+_32755485 0.24 ENSDART00000162188
etfa
electron-transfer-flavoprotein, alpha polypeptide
chr17_-_31579715 0.24 ENSDART00000110167
ENSDART00000191092
rpap1
RNA polymerase II associated protein 1
chr12_+_34891529 0.24 ENSDART00000015643
tbcc
tubulin folding cofactor C
chr10_+_45089820 0.23 ENSDART00000175481
camk2b2
calcium/calmodulin-dependent protein kinase (CaM kinase) II beta 2
chr16_-_32128345 0.23 ENSDART00000102100
ENSDART00000137699
cnot3a
CCR4-NOT transcription complex, subunit 3a
chr19_-_17210760 0.23 ENSDART00000007906
stmn1a
stathmin 1a
chr17_+_37227936 0.23 ENSDART00000076009
hadhab
hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha b
chr10_+_15777258 0.23 ENSDART00000140511
apba1b
amyloid beta (A4) precursor protein-binding, family A, member 1b
chr23_+_43638982 0.23 ENSDART00000168646
slc10a7
solute carrier family 10, member 7
chr10_+_31222433 0.23 ENSDART00000185080
tmem218
transmembrane protein 218
chr8_+_34434345 0.23 ENSDART00000190246
ENSDART00000189447
ENSDART00000185557
ENSDART00000189230
zgc:174461
zgc:174461
chr8_+_41229233 0.23 ENSDART00000131135
zgc:152830
zgc:152830
chr24_-_26328721 0.22 ENSDART00000125468
apodb
apolipoprotein Db
chr14_-_12822 0.22 ENSDART00000180650
ENSDART00000188819
msx1a
muscle segment homeobox 1a
chr21_+_20903244 0.22 ENSDART00000186193
c7b
complement component 7b
chr16_-_46525135 0.22 ENSDART00000169940
ENSDART00000163180
tmem176l.1
transmembrane protein 176l.1
chr2_+_9990491 0.22 ENSDART00000011906
slc35a3b
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3b
chr25_-_6223567 0.22 ENSDART00000067512
psma4
proteasome subunit alpha 4
chr6_-_33878665 0.22 ENSDART00000129916
tmem69
transmembrane protein 69
chr22_-_11623063 0.22 ENSDART00000145653
gcga
glucagon a
chr22_-_9889413 0.22 ENSDART00000081450
si:dkey-253d23.5
si:dkey-253d23.5
chr7_+_12931396 0.21 ENSDART00000184664
fth1a
ferritin, heavy polypeptide 1a
chr12_-_35977702 0.21 ENSDART00000165935
nploc4
NPL4 homolog, ubiquitin recognition factor
chr11_-_38083397 0.21 ENSDART00000086516
ENSDART00000184033
klhdc8a
kelch domain containing 8A
chr22_-_17611742 0.21 ENSDART00000144031
gpx4a
glutathione peroxidase 4a
chr23_-_45407631 0.21 ENSDART00000148484
ENSDART00000150186
zgc:101853
zgc:101853
chr20_-_26822522 0.21 ENSDART00000146326
ENSDART00000046764
ENSDART00000103234
ENSDART00000143267
gmds
GDP-mannose 4,6-dehydratase
chr20_-_48061351 0.21 ENSDART00000164962
prep
prolyl endopeptidase
chr22_+_31039091 0.20 ENSDART00000060005
rpl32
ribosomal protein L32
chr3_-_62403550 0.20 ENSDART00000055055
sox8b
SRY (sex determining region Y)-box 8b
chr16_+_2565433 0.20 ENSDART00000188014
ENSDART00000171378
preb
prolactin regulatory element binding
chr24_-_36270855 0.20 ENSDART00000154858
si:ch211-40k21.5
si:ch211-40k21.5
chr12_-_46959990 0.20 ENSDART00000084557
lhpp
phospholysine phosphohistidine inorganic pyrophosphate phosphatase
chr19_+_47405867 0.19 ENSDART00000041114
psmb2
proteasome subunit beta 2
chr7_+_21275152 0.19 ENSDART00000173612
serpinh2
serine (or cysteine) peptidase inhibitor, clade H, member 2
chr7_+_6879534 0.19 ENSDART00000157731
zgc:175248
zgc:175248
chr22_+_1421212 0.19 ENSDART00000161813
zgc:101130
zgc:101130
chr3_-_61205711 0.19 ENSDART00000055062
pvalb1
parvalbumin 1
chr8_-_22508055 0.19 ENSDART00000101616
si:ch211-261n11.5
si:ch211-261n11.5
chr7_-_30925798 0.19 ENSDART00000149303
sord
sorbitol dehydrogenase
chr7_-_30926030 0.19 ENSDART00000075421
sord
sorbitol dehydrogenase
chr8_+_49117518 0.19 ENSDART00000079631
rad21l1
RAD21 cohesin complex component like 1
chr18_+_44630415 0.19 ENSDART00000098540
bicra
BRD4 interacting chromatin remodeling complex associated protein
chr23_+_19655301 0.19 ENSDART00000104441
ENSDART00000135269
abhd6b
abhydrolase domain containing 6b
chr24_+_3328354 0.19 ENSDART00000147468
bdh1
3-hydroxybutyrate dehydrogenase, type 1
chr3_+_62356578 0.18 ENSDART00000157030
iqck
IQ motif containing K
chr7_-_18168493 0.18 ENSDART00000127428
peli3
pellino E3 ubiquitin protein ligase family member 3
chr21_-_15929041 0.18 ENSDART00000080693
lhx5
LIM homeobox 5
chr21_+_25533531 0.18 ENSDART00000134052
nlrc3l1
NLR family, CARD domain containing 3-like 1
chr11_-_3954691 0.18 ENSDART00000182041
pbrm1
polybromo 1
chr18_+_20468157 0.18 ENSDART00000100665
ENSDART00000147867
ENSDART00000060302
ENSDART00000180370
ddb2
damage-specific DNA binding protein 2
chr9_-_42696408 0.18 ENSDART00000144744
col5a2a
collagen, type V, alpha 2a
chr14_+_9581896 0.18 ENSDART00000114563
tmem129
transmembrane protein 129, E3 ubiquitin protein ligase
chr14_-_4121052 0.18 ENSDART00000167074
irf2
interferon regulatory factor 2
chr19_+_33139164 0.18 ENSDART00000043039
fam84b
family with sequence similarity 84, member B
chr11_+_6881001 0.17 ENSDART00000170331
klhl26
kelch-like family member 26
chr10_-_41940302 0.17 ENSDART00000033121
morn3
MORN repeat containing 3
chr2_-_20574193 0.17 ENSDART00000190448
si:ch211-267e7.3
si:ch211-267e7.3
chr8_+_7975745 0.17 ENSDART00000137920
si:ch211-169p10.1
si:ch211-169p10.1
chr25_+_7571920 0.17 ENSDART00000042928
fuk
fucokinase
chr14_+_5383060 0.17 ENSDART00000187825
lbx2
ladybird homeobox 2
chr23_+_38806861 0.17 ENSDART00000086879
zfp64
zinc finger protein 64 homolog (mouse)
chr3_-_13461056 0.17 ENSDART00000137678
fbxw9
F-box and WD repeat domain containing 9
chr13_-_22907260 0.17 ENSDART00000143097
rufy2
RUN and FYVE domain containing 2
chr16_-_46393154 0.17 ENSDART00000132154
si:ch73-59c19.1
si:ch73-59c19.1
chr15_-_23647078 0.17 ENSDART00000059366
ckmb
creatine kinase, muscle b
chr3_-_13461361 0.16 ENSDART00000080807
fbxw9
F-box and WD repeat domain containing 9
chr10_+_15777064 0.16 ENSDART00000114483
apba1b
amyloid beta (A4) precursor protein-binding, family A, member 1b
chr4_+_391297 0.16 ENSDART00000030215
rpl18a
ribosomal protein L18a
chr12_+_46696867 0.16 ENSDART00000152928
ENSDART00000153445
ENSDART00000123357
ENSDART00000152880
ENSDART00000123834
ENSDART00000174765
ENSDART00000189923
exoc7
exocyst complex component 7
chr14_+_8475007 0.16 ENSDART00000148210
dnajc4
DnaJ (Hsp40) homolog, subfamily C, member 4
chr14_+_31865099 0.16 ENSDART00000189124
tm9sf5
transmembrane 9 superfamily protein member 5
chr7_+_62248514 0.16 ENSDART00000025308
tbc1d19
TBC1 domain family, member 19
chr16_+_40576679 0.15 ENSDART00000169412
ENSDART00000193464
ccne2
cyclin E2
chr20_-_14114078 0.15 ENSDART00000168434
ENSDART00000104032
si:ch211-223m11.2
si:ch211-223m11.2
chr11_-_287670 0.15 ENSDART00000035737
slc11a2
solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
chr20_+_5985329 0.15 ENSDART00000165489
cep128
centrosomal protein 128
chr22_+_7439186 0.15 ENSDART00000190667
zgc:92041
zgc:92041
chr24_+_23716918 0.15 ENSDART00000080332
cops5
COP9 signalosome subunit 5
chr20_+_30578967 0.15 ENSDART00000010494
fgfr1op
FGFR1 oncogene partner
chr25_-_26753196 0.15 ENSDART00000155698
usp3
ubiquitin specific peptidase 3
chr25_+_37209619 0.15 ENSDART00000112192
si:dkey-234i14.3
si:dkey-234i14.3
chr25_-_8138122 0.15 ENSDART00000104659
sergef
secretion regulating guanine nucleotide exchange factor
chr18_+_25752592 0.15 ENSDART00000111767
si:ch211-39k3.2
si:ch211-39k3.2
chr16_-_12173554 0.15 ENSDART00000110567
ENSDART00000155935
clstn3
calsyntenin 3
chr11_+_30647545 0.14 ENSDART00000114792
gb:eh507706
expressed sequence EH507706
chr1_+_21731382 0.14 ENSDART00000054395
pax5
paired box 5
chr2_-_3045861 0.14 ENSDART00000105818
ENSDART00000187575
guk1a
guanylate kinase 1a
chr24_+_39695688 0.14 ENSDART00000109747
zgc:153659
zgc:153659
chr2_-_7605121 0.14 ENSDART00000182099
CABZ01021599.1

chr5_-_31716713 0.14 ENSDART00000131443
dpm2
dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit
chr19_+_43119014 0.14 ENSDART00000023156
eef1a1l1
eukaryotic translation elongation factor 1 alpha 1, like 1
chr9_+_37329036 0.14 ENSDART00000131756
slc15a2
solute carrier family 15 (oligopeptide transporter), member 2
chr23_+_383782 0.14 ENSDART00000055148
zgc:101663
zgc:101663
chr4_-_4834617 0.14 ENSDART00000141539
coa6
cytochrome c oxidase assembly factor 6
chr13_-_24018916 0.14 ENSDART00000026189
cog2
component of oligomeric golgi complex 2
chr10_-_39130839 0.14 ENSDART00000061274
ENSDART00000148648
rps25
ribosomal protein S25
chr23_+_17220986 0.14 ENSDART00000054761
nol4lb
nucleolar protein 4-like b
chr25_+_36325793 0.14 ENSDART00000186973
HIST1H4E
zgc:165555
chr15_-_35252522 0.14 ENSDART00000144153
ENSDART00000059195
mff
mitochondrial fission factor
chr18_+_36769758 0.14 ENSDART00000180375
ENSDART00000136463
ENSDART00000133487
ENSDART00000130206
fosb
FBJ murine osteosarcoma viral oncogene homolog B
chr4_-_9637398 0.14 ENSDART00000150253
dclre1c
DNA cross-link repair 1C, PSO2 homolog (S. cerevisiae)
chr24_-_22756508 0.13 ENSDART00000035409
ENSDART00000146247
zc2hc1a
zinc finger, C2HC-type containing 1A
chr25_-_17494364 0.13 ENSDART00000154134
lrrc29
leucine rich repeat containing 29
chr7_+_48806420 0.13 ENSDART00000083431
cpt1aa
carnitine palmitoyltransferase 1Aa (liver)
chr11_-_6989598 0.13 ENSDART00000102493
ENSDART00000173242
ENSDART00000172896
zgc:173548
zgc:173548
chr24_-_31306724 0.13 ENSDART00000165399
acp5b
acid phosphatase 5b, tartrate resistant
chr19_-_3973567 0.13 ENSDART00000167580
map7d1b
MAP7 domain containing 1b
chr1_-_49530615 0.13 ENSDART00000113315
si:ch211-281g13.5
si:ch211-281g13.5
chr14_+_45566074 0.13 ENSDART00000133477
ENSDART00000185899
zgc:92249
zgc:92249
chr9_+_13229585 0.13 ENSDART00000154879
ENSDART00000141705
carf
calcium responsive transcription factor
chr19_-_32600823 0.13 ENSDART00000134149
ENSDART00000187858
zgc:91944
zgc:91944
chr7_+_15659280 0.13 ENSDART00000173414
mef2ab
myocyte enhancer factor 2ab
chr25_+_35133404 0.13 ENSDART00000188505
hist1h2a2
histone cluster 1 H2A family member 2
chr25_+_10458990 0.13 ENSDART00000130354
ENSDART00000044738
ric8a
RIC8 guanine nucleotide exchange factor A

Network of associatons between targets according to the STRING database.

First level regulatory network of arid5a+arid6

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.1 0.4 GO:0098908 regulation of neuronal action potential(GO:0098908)
0.1 0.5 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.1 0.3 GO:0021564 vagus nerve development(GO:0021564)
0.1 0.3 GO:0009447 polyamine catabolic process(GO:0006598) putrescine catabolic process(GO:0009447)
0.1 0.3 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.1 0.2 GO:0003400 regulation of COPII vesicle coating(GO:0003400) regulation of ER to Golgi vesicle-mediated transport by GTP hydrolysis(GO:0090113)
0.0 0.4 GO:0006167 AMP biosynthetic process(GO:0006167)
0.0 0.4 GO:0019405 alditol catabolic process(GO:0019405)
0.0 0.1 GO:0061400 positive regulation of transcription from RNA polymerase II promoter in response to calcium ion(GO:0061400)
0.0 0.4 GO:0071941 nitrogen cycle metabolic process(GO:0071941)
0.0 0.4 GO:0072395 signal transduction involved in cell cycle checkpoint(GO:0072395)
0.0 0.6 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.3 GO:1902315 cell cycle DNA replication initiation(GO:1902292) nuclear cell cycle DNA replication initiation(GO:1902315) mitotic DNA replication initiation(GO:1902975)
0.0 0.2 GO:0000448 cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000448)
0.0 0.9 GO:0001966 thigmotaxis(GO:0001966)
0.0 0.1 GO:0010039 response to iron ion(GO:0010039)
0.0 0.4 GO:0031998 regulation of fatty acid beta-oxidation(GO:0031998)
0.0 0.1 GO:0000338 protein deneddylation(GO:0000338)
0.0 0.2 GO:0008592 regulation of Toll signaling pathway(GO:0008592)
0.0 0.3 GO:0051315 attachment of mitotic spindle microtubules to kinetochore(GO:0051315)
0.0 0.3 GO:0031643 positive regulation of myelination(GO:0031643)
0.0 0.2 GO:0034650 glucocorticoid biosynthetic process(GO:0006704) cortisol metabolic process(GO:0034650)
0.0 0.2 GO:0060855 venous endothelial cell migration involved in lymph vessel development(GO:0060855)
0.0 0.2 GO:1904105 positive regulation of convergent extension involved in gastrulation(GO:1904105)
0.0 0.5 GO:0042026 protein refolding(GO:0042026)
0.0 0.1 GO:0090183 regulation of morphogenesis of a branching structure(GO:0060688) positive regulation of mesonephros development(GO:0061213) regulation of mesonephros development(GO:0061217) regulation of kidney development(GO:0090183) positive regulation of kidney development(GO:0090184) regulation of branching involved in ureteric bud morphogenesis(GO:0090189) positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.0 0.1 GO:1904088 regulation of convergent extension involved in axis elongation(GO:1901232) positive regulation of epiboly involved in gastrulation with mouth forming second(GO:1904088)
0.0 0.2 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.0 0.1 GO:0032602 chemokine production(GO:0032602)
0.0 0.1 GO:0036363 transforming growth factor beta activation(GO:0036363)
0.0 0.3 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 0.1 GO:0010807 regulation of synaptic vesicle priming(GO:0010807)
0.0 0.3 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.3 GO:0006108 malate metabolic process(GO:0006108)
0.0 0.1 GO:0086005 ventricular cardiac muscle cell action potential(GO:0086005)
0.0 0.1 GO:0035739 negative regulation of interferon-gamma production(GO:0032689) CD4-positive, alpha-beta T cell proliferation(GO:0035739) regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000561) negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562)
0.0 0.4 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.0 0.1 GO:0010481 epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
0.0 0.1 GO:0060295 regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
0.0 0.1 GO:0034447 very-low-density lipoprotein particle clearance(GO:0034447)
0.0 0.1 GO:1904251 regulation of bile acid biosynthetic process(GO:0070857) regulation of bile acid metabolic process(GO:1904251)
0.0 0.2 GO:2000036 regulation of stem cell population maintenance(GO:2000036)
0.0 0.2 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 0.1 GO:0070086 ubiquitin-dependent endocytosis(GO:0070086)
0.0 0.1 GO:0002753 cytoplasmic pattern recognition receptor signaling pathway(GO:0002753)
0.0 0.1 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.3 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.2 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.0 0.1 GO:0045938 positive regulation of circadian sleep/wake cycle, sleep(GO:0045938)
0.0 0.1 GO:0060114 vestibular receptor cell differentiation(GO:0060114) vestibular receptor cell development(GO:0060118)
0.0 0.2 GO:0007035 vacuolar acidification(GO:0007035) pH reduction(GO:0045851) intracellular pH reduction(GO:0051452)
0.0 0.5 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.0 0.1 GO:0010693 regulation of alkaline phosphatase activity(GO:0010692) negative regulation of alkaline phosphatase activity(GO:0010693)
0.0 0.4 GO:0015671 oxygen transport(GO:0015671)
0.0 0.1 GO:0072047 proximal/distal pattern formation involved in nephron development(GO:0072047) proximal/distal pattern formation involved in pronephric nephron development(GO:0072196)
0.0 0.3 GO:0034629 cellular protein complex localization(GO:0034629)
0.0 0.0 GO:0003097 renal water homeostasis(GO:0003091) renal water transport(GO:0003097)
0.0 0.1 GO:0003322 pancreatic A cell development(GO:0003322)
0.0 0.1 GO:0003261 cardiac muscle progenitor cell migration to the midline involved in heart field formation(GO:0003261)
0.0 0.4 GO:0000469 cleavage involved in rRNA processing(GO:0000469)
0.0 0.5 GO:0032482 Rab protein signal transduction(GO:0032482)
0.0 0.1 GO:0033206 meiotic cytokinesis(GO:0033206) polar body extrusion after meiotic divisions(GO:0040038)
0.0 0.1 GO:0046952 ketone body catabolic process(GO:0046952)
0.0 0.1 GO:0006707 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.2 GO:0015781 pyrimidine nucleotide-sugar transport(GO:0015781) pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.0 0.1 GO:0006012 galactose metabolic process(GO:0006012)
0.0 0.1 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.0 0.1 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 0.1 GO:0043247 protection from non-homologous end joining at telomere(GO:0031848) telomere maintenance in response to DNA damage(GO:0043247)
0.0 0.4 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.2 GO:0006603 phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
0.0 0.0 GO:0046379 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.0 0.0 GO:0007638 mechanosensory behavior(GO:0007638)
0.0 0.1 GO:0045453 bone resorption(GO:0045453)
0.0 0.3 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.1 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.0 0.1 GO:0019348 dolichol metabolic process(GO:0019348)
0.0 0.2 GO:2001235 positive regulation of apoptotic signaling pathway(GO:2001235)
0.0 0.0 GO:0021611 facial nerve formation(GO:0021611)
0.0 0.0 GO:0099543 trans-synaptic signaling by soluble gas(GO:0099543) trans-synaptic signaling by nitric oxide(GO:0099548)
0.0 0.1 GO:2000316 regulation of T-helper 17 type immune response(GO:2000316) negative regulation of T-helper 17 type immune response(GO:2000317) regulation of T-helper 17 cell differentiation(GO:2000319) negative regulation of T-helper 17 cell differentiation(GO:2000320) regulation of T-helper 17 cell lineage commitment(GO:2000328) negative regulation of T-helper 17 cell lineage commitment(GO:2000329)
0.0 0.0 GO:0045987 positive regulation of smooth muscle contraction(GO:0045987)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 0.5 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.1 0.4 GO:1990130 Iml1 complex(GO:1990130)
0.1 0.3 GO:0031262 Ndc80 complex(GO:0031262)
0.0 0.5 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.5 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.2 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.5 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.1 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.0 0.2 GO:0097134 cyclin E1-CDK2 complex(GO:0097134)
0.0 0.1 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 0.4 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.1 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.4 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.1 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0 0.3 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 0.3 GO:1990246 uniplex complex(GO:1990246)
0.0 0.3 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.2 GO:0030892 nuclear cohesin complex(GO:0000798) mitotic cohesin complex(GO:0030892) nuclear mitotic cohesin complex(GO:0034990) nuclear meiotic cohesin complex(GO:0034991)
0.0 0.3 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.4 GO:0005833 hemoglobin complex(GO:0005833)
0.0 0.2 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 0.1 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.0 0.3 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 0.2 GO:0016586 RSC complex(GO:0016586)
0.0 0.2 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.3 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 0.1 GO:0035301 Hedgehog signaling complex(GO:0035301)
0.0 0.8 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.4 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.1 GO:0070419 nonhomologous end joining complex(GO:0070419)
0.0 0.1 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 0.1 GO:0030314 junctional membrane complex(GO:0030314)
0.0 0.2 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 0.3 GO:0042555 MCM complex(GO:0042555)
0.0 0.3 GO:0045239 tricarboxylic acid cycle enzyme complex(GO:0045239)
0.0 0.2 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.3 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.2 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.2 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.1 GO:0042824 MHC class I peptide loading complex(GO:0042824)
0.0 0.1 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.3 GO:0060170 ciliary membrane(GO:0060170)
0.0 0.4 GO:0030686 90S preribosome(GO:0030686)
0.0 0.1 GO:0005883 neurofilament(GO:0005883)
0.0 0.3 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.7 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.2 GO:0005839 proteasome core complex(GO:0005839)
0.0 0.1 GO:0045273 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0061711 N(6)-L-threonylcarbamoyladenine synthase(GO:0061711)
0.1 0.4 GO:0033961 cis-stilbene-oxide hydrolase activity(GO:0033961)
0.1 0.4 GO:0016842 amidine-lyase activity(GO:0016842)
0.1 0.5 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.1 0.8 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.1 0.2 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.1 0.3 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
0.1 0.4 GO:0098809 nitrite reductase activity(GO:0098809)
0.0 0.2 GO:0004427 inorganic diphosphatase activity(GO:0004427) protein histidine phosphatase activity(GO:0101006)
0.0 0.1 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086)
0.0 0.1 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.2 GO:0031769 glucagon receptor binding(GO:0031769)
0.0 0.2 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.0 0.5 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.2 GO:0042974 retinoic acid receptor binding(GO:0042974)
0.0 0.2 GO:0019808 polyamine binding(GO:0019808) spermidine binding(GO:0019809)
0.0 0.1 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 0.8 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.1 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.3 GO:0008199 ferric iron binding(GO:0008199)
0.0 0.1 GO:0030116 glial cell-derived neurotrophic factor receptor binding(GO:0030116)
0.0 0.1 GO:0070004 cysteine-type exopeptidase activity(GO:0070004)
0.0 0.5 GO:0030515 snoRNA binding(GO:0030515)
0.0 0.1 GO:0046978 TAP1 binding(GO:0046978)
0.0 0.1 GO:0016803 ether hydrolase activity(GO:0016803)
0.0 0.2 GO:0051731 polynucleotide 5'-hydroxyl-kinase activity(GO:0051731)
0.0 0.4 GO:0019825 oxygen transporter activity(GO:0005344) oxygen binding(GO:0019825)
0.0 0.2 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.0 0.4 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.1 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.1 GO:0071916 dipeptide transporter activity(GO:0042936) dipeptide transmembrane transporter activity(GO:0071916)
0.0 0.1 GO:0033781 cholesterol 24-hydroxylase activity(GO:0033781)
0.0 0.1 GO:0016416 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.0 0.1 GO:0000104 succinate dehydrogenase activity(GO:0000104)
0.0 0.1 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.0 0.1 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.0 0.4 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.1 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.1 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0 0.2 GO:0051117 ATPase binding(GO:0051117)
0.0 0.1 GO:0008743 L-threonine 3-dehydrogenase activity(GO:0008743)
0.0 0.1 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.0 0.1 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
0.0 0.1 GO:0031843 neuropeptide Y receptor binding(GO:0031841) type 2 neuropeptide Y receptor binding(GO:0031843)
0.0 0.1 GO:0071253 connexin binding(GO:0071253)
0.0 0.1 GO:0048019 receptor antagonist activity(GO:0048019)
0.0 0.1 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.0 0.1 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 3.6 GO:0030246 carbohydrate binding(GO:0030246)
0.0 0.1 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 0.2 GO:0016775 creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
0.0 0.2 GO:0008417 fucosyltransferase activity(GO:0008417)
0.0 0.1 GO:0004743 pyruvate kinase activity(GO:0004743)
0.0 0.1 GO:0003691 double-stranded telomeric DNA binding(GO:0003691)
0.0 0.3 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.1 GO:0019841 retinol binding(GO:0019841)
0.0 2.1 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.1 GO:0000700 mismatch base pair DNA N-glycosylase activity(GO:0000700) pyrimidine-specific mismatch base pair DNA N-glycosylase activity(GO:0008263)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 PID IFNG PATHWAY IFN-gamma pathway
0.0 0.3 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.1 PID REELIN PATHWAY Reelin signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.5 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.4 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.4 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.3 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 0.4 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.3 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 0.2 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 0.3 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.3 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.1 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 0.3 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.2 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.4 REACTOME PIP3 ACTIVATES AKT SIGNALING Genes involved in PIP3 activates AKT signaling
0.0 0.1 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.6 REACTOME P53 DEPENDENT G1 DNA DAMAGE RESPONSE Genes involved in p53-Dependent G1 DNA Damage Response
0.0 0.1 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.2 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0 0.6 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport