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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for arxa

Z-value: 0.80

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Transcription factors associated with arxa

Gene Symbol Gene ID Gene Info
arxa
ENSDARG00000058011 aristaless related homeobox a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
arxadr11_v1_chr24_-_23942722_23942722-0.911.6e-07Click!

Activity profile of arxa motif

Sorted Z-values of arxa motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr5_+_37903790 3.43 ENSDART00000162470
tmprss4b
transmembrane protease, serine 4b
chr25_+_22320738 2.59 ENSDART00000073566
cyp11a1
cytochrome P450, family 11, subfamily A, polypeptide 1
chr11_-_39118882 1.94 ENSDART00000113185
ENSDART00000156526
ap5b1
adaptor-related protein complex 5, beta 1 subunit
chr8_-_53044300 1.88 ENSDART00000191653
nr6a1a
nuclear receptor subfamily 6, group A, member 1a
chr3_+_7808459 1.79 ENSDART00000162374
hook2
hook microtubule-tethering protein 2
chr12_-_33357655 1.71 ENSDART00000066233
ENSDART00000148165
slc16a3
solute carrier family 16 (monocarboxylate transporter), member 3
chr20_+_29209767 1.71 ENSDART00000141252
katnbl1
katanin p80 subunit B-like 1
chr7_-_51727760 1.68 ENSDART00000174180
hdac8
histone deacetylase 8
chr6_+_36839509 1.62 ENSDART00000190605
ENSDART00000104160
zgc:110788
zgc:110788
chr20_+_29209926 1.60 ENSDART00000152949
ENSDART00000153016
katnbl1
katanin p80 subunit B-like 1
chr9_+_45493341 1.57 ENSDART00000145616
adarb1b
adenosine deaminase, RNA-specific, B1b
chr20_+_29209615 1.54 ENSDART00000062350
katnbl1
katanin p80 subunit B-like 1
chr14_-_33481428 1.52 ENSDART00000147059
ENSDART00000140001
ENSDART00000124242
ENSDART00000164836
ENSDART00000190104
ENSDART00000186833
ENSDART00000180873
lamp2
lysosomal-associated membrane protein 2
chr18_-_40708537 1.51 ENSDART00000077577
si:ch211-132b12.8
si:ch211-132b12.8
chr21_+_13387965 1.48 ENSDART00000134347
zgc:113162
zgc:113162
chr10_-_2788668 1.45 ENSDART00000131749
ENSDART00000124356
ENSDART00000085031
ash2l
ash2 (absent, small, or homeotic)-like (Drosophila)
chr9_+_54039006 1.39 ENSDART00000112441
tlr7
toll-like receptor 7
chr21_-_30082414 1.39 ENSDART00000157307
ENSDART00000155188
ccnjl
cyclin J-like
chr23_-_36303216 1.39 ENSDART00000188720
cbx5
chromobox homolog 5 (HP1 alpha homolog, Drosophila)
chr21_+_43172506 1.37 ENSDART00000121725
zcchc10
zinc finger, CCHC domain containing 10
chr18_+_39106722 1.33 ENSDART00000122377
bcl2l10
BCL2 like 10
chr20_-_51831816 1.31 ENSDART00000060505
mia3
melanoma inhibitory activity family, member 3
chr16_-_7793457 1.26 ENSDART00000113483
trim71
tripartite motif containing 71, E3 ubiquitin protein ligase
chr4_+_2482046 1.25 ENSDART00000103371
zdhhc17
zinc finger, DHHC-type containing 17
chr24_+_29912509 1.25 ENSDART00000168422
frrs1b
ferric-chelate reductase 1b
chr23_+_36460239 1.19 ENSDART00000172441
lima1a
LIM domain and actin binding 1a
chr17_-_40956035 1.18 ENSDART00000124715
si:dkey-16j16.4
si:dkey-16j16.4
chr18_+_35128685 1.15 ENSDART00000151579
si:ch211-195m9.3
si:ch211-195m9.3
chr2_-_26596794 1.15 ENSDART00000134685
ENSDART00000056787
zgc:113691
zgc:113691
chr4_-_5108844 1.13 ENSDART00000132666
ENSDART00000136096
tmem209
transmembrane protein 209
chr1_+_47499888 1.13 ENSDART00000027624
stn1
STN1, CST complex subunit
chr16_+_54209504 1.12 ENSDART00000020033
xrcc1
X-ray repair complementing defective repair in Chinese hamster cells 1
chr11_-_44979281 1.12 ENSDART00000190972
ldb1b
LIM-domain binding 1b
chr2_-_1622641 1.11 ENSDART00000082143
prkacbb
protein kinase, cAMP-dependent, catalytic, beta b
chr4_-_3353595 1.11 ENSDART00000009076
pik3cg
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
chr24_+_19415124 1.08 ENSDART00000186931
sulf1
sulfatase 1
chr9_+_24065855 1.06 ENSDART00000161468
ENSDART00000171577
ENSDART00000172743
ENSDART00000159324
ENSDART00000079689
ENSDART00000023196
ENSDART00000101577
lrrfip1a
leucine rich repeat (in FLII) interacting protein 1a
chr1_+_19433004 1.06 ENSDART00000133959
clockb
clock circadian regulator b
chr25_-_21031007 1.05 ENSDART00000138985
gnaia
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide a
chr7_-_5375214 1.04 ENSDART00000033316
vangl2
VANGL planar cell polarity protein 2
chr16_-_31351419 1.03 ENSDART00000178298
ENSDART00000018091
mroh1
maestro heat-like repeat family member 1
chr8_-_53044089 1.02 ENSDART00000135982
nr6a1a
nuclear receptor subfamily 6, group A, member 1a
chr8_-_50888806 1.02 ENSDART00000053750
acsl2
acyl-CoA synthetase long chain family member 2
chr2_-_17392799 1.01 ENSDART00000136470
ENSDART00000141188
st3gal3b
ST3 beta-galactoside alpha-2,3-sialyltransferase 3b
chr6_+_12527725 1.01 ENSDART00000149328
stk24b
serine/threonine kinase 24b (STE20 homolog, yeast)
chr21_-_2814709 1.00 ENSDART00000097664
SEMA4D
semaphorin 4D
chr1_+_47165842 0.99 ENSDART00000053152
ENSDART00000167051
cbr1
carbonyl reductase 1
chr4_-_5019113 0.98 ENSDART00000189321
ENSDART00000081990
strip2
striatin interacting protein 2
chr10_+_11261576 0.98 ENSDART00000155333
hsdl2
hydroxysteroid dehydrogenase like 2
chr6_-_55399214 0.96 ENSDART00000168367
ctsa
cathepsin A
chr11_+_11152214 0.96 ENSDART00000148030
ly75
lymphocyte antigen 75
chr14_-_7045009 0.96 ENSDART00000112082
rufy1
RUN and FYVE domain containing 1
chr21_-_4793686 0.94 ENSDART00000158232
notch1a
notch 1a
chr2_-_38284648 0.94 ENSDART00000148281
ENSDART00000132621
si:ch211-14a17.7
si:ch211-14a17.7
chr11_+_31323746 0.94 ENSDART00000180220
ENSDART00000189937
sipa1l2
signal-induced proliferation-associated 1 like 2
chr16_-_27677930 0.92 ENSDART00000145991
tbrg4
transforming growth factor beta regulator 4
chr6_+_40922572 0.92 ENSDART00000133599
ENSDART00000002728
ENSDART00000145153
eif4enif1
eukaryotic translation initiation factor 4E nuclear import factor 1
chr12_-_48188928 0.91 ENSDART00000184384
pald1a
phosphatase domain containing, paladin 1a
chr8_-_39822917 0.90 ENSDART00000067843
zgc:162025
zgc:162025
chr23_+_4709607 0.88 ENSDART00000166503
ENSDART00000158752
ENSDART00000163860
ENSDART00000172739
raf1a
raf1a
Raf-1 proto-oncogene, serine/threonine kinase a
Raf-1 proto-oncogene, serine/threonine kinase a
chr7_+_24023653 0.87 ENSDART00000141165
tinf2
TERF1 (TRF1)-interacting nuclear factor 2
chr17_-_9950911 0.87 ENSDART00000105117
sptssa
serine palmitoyltransferase, small subunit A
chr21_+_21195487 0.86 ENSDART00000181746
ENSDART00000184832
rictorb
RPTOR independent companion of MTOR, complex 2b
chr9_-_34937025 0.86 ENSDART00000137888
cdc16
cell division cycle 16 homolog (S. cerevisiae)
chr20_+_22799857 0.86 ENSDART00000058527
scfd2
sec1 family domain containing 2
chr14_+_10954345 0.85 ENSDART00000106658
zdhhc15b
zinc finger, DHHC-type containing 15b
chr9_-_11676491 0.84 ENSDART00000022358
zc3h15
zinc finger CCCH-type containing 15
chr7_-_50410524 0.84 ENSDART00000083346
hypk
huntingtin interacting protein K
chr14_-_48765262 0.84 ENSDART00000166463
cnot6b
CCR4-NOT transcription complex, subunit 6b
chr5_-_52010122 0.83 ENSDART00000073627
ENSDART00000163898
ENSDART00000051003
cdk7
cyclin-dependent kinase 7
chr22_-_20812822 0.82 ENSDART00000193778
dot1l
DOT1-like histone H3K79 methyltransferase
chr11_+_31324335 0.82 ENSDART00000088093
sipa1l2
signal-induced proliferation-associated 1 like 2
chr1_+_27977297 0.81 ENSDART00000180692
ENSDART00000166819
sugt1
SGT1 homolog, MIS12 kinetochore complex assembly cochaperone
chr20_+_20731052 0.79 ENSDART00000047662
ppp1r13bb
protein phosphatase 1, regulatory subunit 13Bb
chr5_-_11809710 0.79 ENSDART00000186998
ENSDART00000181363
ENSDART00000180681
nf2a
neurofibromin 2a (merlin)
chr1_+_35985813 0.78 ENSDART00000179634
ENSDART00000139636
ENSDART00000175902
zgc:152968
zgc:152968
chr22_+_11775269 0.78 ENSDART00000140272
krt96
keratin 96
chr7_-_8712148 0.77 ENSDART00000065488
tex261
testis expressed 261
chr2_-_17393216 0.77 ENSDART00000123137
st3gal3b
ST3 beta-galactoside alpha-2,3-sialyltransferase 3b
chr20_+_22799641 0.77 ENSDART00000131132
scfd2
sec1 family domain containing 2
chr22_+_23359369 0.76 ENSDART00000170886
dennd1b
DENN/MADD domain containing 1B
chr16_-_28658341 0.76 ENSDART00000148456
abcb4
ATP-binding cassette, sub-family B (MDR/TAP), member 4
chr14_+_34558480 0.75 ENSDART00000075170
pttg1
pituitary tumor-transforming 1
chr2_+_1988036 0.74 ENSDART00000155956
ssx2ipa
synovial sarcoma, X breakpoint 2 interacting protein a
chr9_+_29643036 0.74 ENSDART00000023210
ENSDART00000175160
trim13
tripartite motif containing 13
chr2_-_10877765 0.74 ENSDART00000100607
cdc7
cell division cycle 7 homolog (S. cerevisiae)
chr25_+_30131055 0.73 ENSDART00000152705
api5
apoptosis inhibitor 5
chr13_-_31017960 0.73 ENSDART00000145287
wdfy4
WDFY family member 4
chr13_-_35808904 0.73 ENSDART00000171667
map3k4
mitogen-activated protein kinase kinase kinase 4
chr23_+_1029450 0.71 ENSDART00000189196
si:zfos-905g2.1
si:zfos-905g2.1
chr21_-_44081540 0.71 ENSDART00000130833
FO704810.1

chr22_+_737211 0.71 ENSDART00000017305
znf76
zinc finger protein 76
chr6_-_40922971 0.70 ENSDART00000155363
sfi1
SFI1 centrin binding protein
chr20_+_20731633 0.70 ENSDART00000191952
ENSDART00000165224
ppp1r13bb
protein phosphatase 1, regulatory subunit 13Bb
chr20_-_40360571 0.68 ENSDART00000144768
smpdl3a
sphingomyelin phosphodiesterase, acid-like 3A
chr13_-_36798204 0.68 ENSDART00000012357
sav1
salvador family WW domain containing protein 1
chr12_-_314899 0.67 ENSDART00000066579
pts
6-pyruvoyltetrahydropterin synthase
chr4_-_2975461 0.66 ENSDART00000150794
plekha5
pleckstrin homology domain containing, family A member 5
chr24_-_29586082 0.65 ENSDART00000136763
vav3a
vav 3 guanine nucleotide exchange factor a
chr13_+_15656042 0.64 ENSDART00000134240
mark3a
MAP/microtubule affinity-regulating kinase 3a
chr13_+_38817871 0.63 ENSDART00000187708
col19a1
collagen, type XIX, alpha 1
chr14_+_30795559 0.63 ENSDART00000006132
cfl1
cofilin 1
chr24_-_18809433 0.62 ENSDART00000152009
arfgef1
ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited)
chr9_+_43799829 0.62 ENSDART00000186240
ube2e3
ubiquitin-conjugating enzyme E2E 3 (UBC4/5 homolog, yeast)
chr3_-_26787430 0.61 ENSDART00000087047
rab40c
RAB40c, member RAS oncogene family
chr4_-_1801519 0.60 ENSDART00000188604
ENSDART00000135749
nudt4b
nudix (nucleoside diphosphate linked moiety X)-type motif 4b
chr20_+_38458084 0.60 ENSDART00000020153
ENSDART00000135912
coq8a
coenzyme Q8A
chr7_+_6941583 0.59 ENSDART00000160709
ENSDART00000157634
rbm14b
RNA binding motif protein 14b
chr17_+_50076501 0.56 ENSDART00000156303
vps39
vacuolar protein sorting 39 homolog (S. cerevisiae)
chr2_+_2169337 0.55 ENSDART00000179939
higd1a
HIG1 hypoxia inducible domain family, member 1A
chr16_+_13818500 0.55 ENSDART00000135245
flcn
folliculin
chr15_+_31590224 0.54 ENSDART00000159634
b3glcta
beta 3-glucosyltransferase a
chr12_+_1139690 0.54 ENSDART00000160442
CABZ01072885.1

chr4_+_5255041 0.51 ENSDART00000137966
ccdc167
coiled-coil domain containing 167
chr16_+_13818743 0.49 ENSDART00000090191
flcn
folliculin
chr23_-_31969786 0.46 ENSDART00000134550
ormdl2
ORMDL sphingolipid biosynthesis regulator 2
chr3_+_40164129 0.46 ENSDART00000102526
gfer
growth factor, augmenter of liver regeneration (ERV1 homolog, S. cerevisiae)
chr7_+_7019911 0.45 ENSDART00000172421
rbm14b
RNA binding motif protein 14b
chr22_+_30137374 0.44 ENSDART00000187808
add3a
adducin 3 (gamma) a
chr8_+_25079470 0.43 ENSDART00000000744
sypl2b
synaptophysin-like 2b
chr3_-_21280373 0.42 ENSDART00000003939
syngr1a
synaptogyrin 1a
chr6_+_7533601 0.40 ENSDART00000057823
pa2g4a
proliferation-associated 2G4, a
chr10_-_3138859 0.39 ENSDART00000190606
ube2l3a
ubiquitin-conjugating enzyme E2L 3a
chr14_+_14806692 0.39 ENSDART00000193050
fhdc2
FH2 domain containing 2
chr21_+_6394929 0.39 ENSDART00000138600
si:ch211-225g23.1
si:ch211-225g23.1
chr2_+_35806672 0.37 ENSDART00000137384
rasal2
RAS protein activator like 2
chr25_+_7241084 0.37 ENSDART00000190501
ENSDART00000190588
hmg20a
high mobility group 20A
chr7_-_7692723 0.36 ENSDART00000183352
aadat
aminoadipate aminotransferase
chr4_+_21129752 0.36 ENSDART00000169764
syt1a
synaptotagmin Ia
chr15_-_47115787 0.35 ENSDART00000192601
CABZ01079081.1

chr2_+_10878406 0.35 ENSDART00000091497
tceanc2
transcription elongation factor A (SII) N-terminal and central domain containing 2
chr7_-_7692992 0.34 ENSDART00000192619
aadat
aminoadipate aminotransferase
chr9_+_2574122 0.34 ENSDART00000166326
ENSDART00000191822
CIR1
si:ch73-167c12.2
chr22_-_16443199 0.34 ENSDART00000006290
ENSDART00000193335
plekhb2
pleckstrin homology domain containing, family B (evectins) member 2
chr3_+_431208 0.33 ENSDART00000154296
ENSDART00000048733
si:ch73-308m11.1
si:dkey-167k11.5
si:ch73-308m11.1
si:dkey-167k11.5
chr10_-_3138403 0.33 ENSDART00000183365
ube2l3a
ubiquitin-conjugating enzyme E2L 3a
chr8_+_17167876 0.33 ENSDART00000134665
cenph
centromere protein H
chr12_+_22580579 0.32 ENSDART00000171725
ENSDART00000192290
capgb
capping protein (actin filament), gelsolin-like b
chr2_+_56657804 0.31 ENSDART00000113964
POLR2E (1 of many)
RNA polymerase II subunit E
chr5_+_24156170 0.31 ENSDART00000136570
slc25a15b
solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15b
chr7_-_51368681 0.31 ENSDART00000146385
arhgap36
Rho GTPase activating protein 36
chr10_+_42521943 0.30 ENSDART00000010420
ENSDART00000075303
actr1
ARP1 actin related protein 1, centractin
chr10_+_35358675 0.30 ENSDART00000193263
si:dkey-259j3.5
si:dkey-259j3.5
chr12_+_2381213 0.29 ENSDART00000188007
LO018238.1

chr2_+_11923615 0.27 ENSDART00000126118
trove2
TROVE domain family, member 2
chr13_+_24756486 0.27 ENSDART00000137074
col17a1b
collagen, type XVII, alpha 1b
chr9_-_394088 0.27 ENSDART00000169014
si:dkey-11f4.7
si:dkey-11f4.7
chr19_+_2631565 0.27 ENSDART00000171487
fam126a
family with sequence similarity 126, member A
chr5_+_66312359 0.26 ENSDART00000137534
malt1
MALT paracaspase 1
chr8_-_51930826 0.26 ENSDART00000109785
cabin1
calcineurin binding protein 1
chr21_-_15200556 0.25 ENSDART00000141809
sfswap
splicing factor SWAP
chr16_-_31622777 0.25 ENSDART00000137311
ENSDART00000002930
phf20l1
PHD finger protein 20 like 1
chr8_+_7801060 0.24 ENSDART00000161618
tfe3a
transcription factor binding to IGHM enhancer 3a
chr18_+_13275735 0.23 ENSDART00000148127
plcg2
phospholipase C, gamma 2
chr7_-_24520866 0.23 ENSDART00000077039
faah2b
fatty acid amide hydrolase 2b
chr22_+_15633013 0.22 ENSDART00000188095
ENSDART00000048763
CABZ01090041.1

chr23_-_33350990 0.22 ENSDART00000144831
si:ch211-226m16.2
si:ch211-226m16.2
chr7_+_24573721 0.20 ENSDART00000173938
ENSDART00000173681
si:dkeyp-75h12.7
si:dkeyp-75h12.7
chr17_+_44697604 0.20 ENSDART00000156625
pgfb
placental growth factor b
chr20_-_37813863 0.20 ENSDART00000147529
batf3
basic leucine zipper transcription factor, ATF-like 3
chr16_+_19029297 0.20 ENSDART00000115263
ENSDART00000114954
rapgef5b
Rap guanine nucleotide exchange factor (GEF) 5b
chr20_-_29864390 0.18 ENSDART00000161834
ENSDART00000132278
rnf144ab
ring finger protein 144ab
chr15_-_38129845 0.18 ENSDART00000057095
si:dkey-24p1.1
si:dkey-24p1.1
chr17_+_20589553 0.18 ENSDART00000154447
si:ch73-288o11.4
si:ch73-288o11.4
chr2_-_9989919 0.18 ENSDART00000180213
ENSDART00000184369
imp3
IMP3, U3 small nucleolar ribonucleoprotein, homolog (yeast)
chr14_+_36521005 0.17 ENSDART00000192286
TENM3
si:dkey-237h12.3
chr16_-_32837806 0.17 ENSDART00000003997
MCHR2
si:dkey-165n16.5
chr17_+_16564921 0.16 ENSDART00000151904
foxn3
forkhead box N3
chr19_+_12237945 0.16 ENSDART00000190034
grhl2b
grainyhead-like transcription factor 2b
chr10_+_34010494 0.15 ENSDART00000186836
ENSDART00000114703
kl
klotho
chr23_-_333457 0.15 ENSDART00000114486
uhrf1bp1
UHRF1 binding protein 1
chr13_+_7049823 0.14 ENSDART00000178997
ENSDART00000161443
rnaset2
ribonuclease T2
chr7_+_54642005 0.13 ENSDART00000171864
fgf19
fibroblast growth factor 19
chr14_-_41388178 0.13 ENSDART00000124532
ENSDART00000125016
ENSDART00000169247
cstf2
cleavage stimulation factor, 3' pre-RNA, subunit 2
chr15_+_41932069 0.13 ENSDART00000143007
si:ch211-191a16.2
si:ch211-191a16.2
chr5_+_32076109 0.12 ENSDART00000051357
ENSDART00000144510
zmat5
zinc finger, matrin-type 5
chr7_-_66868543 0.11 ENSDART00000149680
ampd3a
adenosine monophosphate deaminase 3a
chr13_-_4707018 0.11 ENSDART00000128422
oit3
oncoprotein induced transcript 3
chr25_+_13620555 0.10 ENSDART00000163642
si:ch211-172l8.4
si:ch211-172l8.4
chr8_+_18011522 0.10 ENSDART00000136756
ssbp3b
single stranded DNA binding protein 3b
chr3_-_29941357 0.10 ENSDART00000147732
ENSDART00000137973
ENSDART00000103523
grna
granulin a
chr14_-_470505 0.10 ENSDART00000067147
ANKRD50
ankyrin repeat domain 50
chr7_+_22543963 0.09 ENSDART00000101528
chrnb1
cholinergic receptor, nicotinic, beta 1 (muscle)
chr20_+_19176959 0.09 ENSDART00000163276
ENSDART00000020099
blk
BLK proto-oncogene, Src family tyrosine kinase
chr10_+_31248036 0.09 ENSDART00000193574
robo4
roundabout, axon guidance receptor, homolog 4 (Drosophila)
chr11_+_2506516 0.09 ENSDART00000130886
ENSDART00000189767
NABP2
si:ch73-190f16.2
chr6_-_52788213 0.09 ENSDART00000179880
rbpjl
recombination signal binding protein for immunoglobulin kappa J region-like
chr16_-_30434279 0.09 ENSDART00000018504
zgc:77086
zgc:77086
chr22_-_14739491 0.09 ENSDART00000133385
lrp1ba
low density lipoprotein receptor-related protein 1Ba
chr5_-_68074592 0.08 ENSDART00000165052
ENSDART00000018792
spag7
sperm associated antigen 7
chr4_+_9400012 0.08 ENSDART00000191960
tmtc1
transmembrane and tetratricopeptide repeat containing 1
chr2_+_20605925 0.07 ENSDART00000191510
olfml2bb
olfactomedin-like 2Bb
chr13_-_14487524 0.07 ENSDART00000141103
gfra4a
GDNF family receptor alpha 4a
chr8_+_26059677 0.07 ENSDART00000009178
impdh2
IMP (inosine 5'-monophosphate) dehydrogenase 2
chr20_+_3108597 0.07 ENSDART00000133435
CEP170B (1 of many)
si:ch73-212j7.1
chr25_-_28674739 0.07 ENSDART00000067073
lrrc10
leucine rich repeat containing 10
chr9_-_43538328 0.07 ENSDART00000140526
znf385b
zinc finger protein 385B
chr5_-_42082730 0.07 ENSDART00000135625
cxcl11.5
chemokine (C-X-C motif) ligand 11, duplicate 5
chr2_-_48512450 0.07 ENSDART00000160132
CR391991.1

chr4_+_59845617 0.06 ENSDART00000167626
ENSDART00000123157
si:dkey-196n19.2
si:dkey-196n19.2

Network of associatons between targets according to the STRING database.

First level regulatory network of arxa

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.6 GO:0006700 C21-steroid hormone biosynthetic process(GO:0006700)
0.5 1.4 GO:0034154 toll-like receptor 7 signaling pathway(GO:0034154)
0.3 0.9 GO:0021531 spinal cord radial glial cell differentiation(GO:0021531)
0.3 1.3 GO:0010586 miRNA metabolic process(GO:0010586)
0.2 1.2 GO:0000012 single strand break repair(GO:0000012)
0.2 0.6 GO:0030043 actin filament fragmentation(GO:0030043)
0.2 1.7 GO:0070933 histone H4 deacetylation(GO:0070933)
0.2 1.0 GO:0008591 regulation of Wnt signaling pathway, calcium modulating pathway(GO:0008591)
0.2 1.3 GO:0048011 neurotrophin TRK receptor signaling pathway(GO:0048011)
0.2 0.8 GO:0034729 histone H3-K79 methylation(GO:0034729) regulation of transcription regulatory region DNA binding(GO:2000677)
0.2 0.9 GO:0097065 anterior head development(GO:0097065)
0.1 1.0 GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.1 1.5 GO:0006622 protein targeting to lysosome(GO:0006622)
0.1 1.1 GO:0021910 smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021910) regulation of myotome development(GO:2000290)
0.1 1.3 GO:0051279 regulation of calcium ion transport into cytosol(GO:0010522) regulation of release of sequestered calcium ion into cytosol(GO:0051279)
0.1 1.6 GO:0006382 adenosine to inosine editing(GO:0006382)
0.1 0.6 GO:1901909 diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.1 0.5 GO:1905038 regulation of sphingolipid biosynthetic process(GO:0090153) negative regulation of sphingolipid biosynthetic process(GO:0090155) negative regulation of ceramide biosynthetic process(GO:1900060) regulation of membrane lipid metabolic process(GO:1905038) regulation of ceramide biosynthetic process(GO:2000303)
0.1 0.9 GO:0044528 regulation of mitochondrial mRNA stability(GO:0044528)
0.1 0.3 GO:1990575 mitochondrial ornithine transport(GO:0000066) mitochondrial L-ornithine transmembrane transport(GO:1990575)
0.1 0.6 GO:0097250 mitochondrial respiratory chain supercomplex assembly(GO:0097250)
0.1 2.0 GO:0016233 telomere capping(GO:0016233)
0.1 0.9 GO:0038203 TORC2 signaling(GO:0038203)
0.1 1.3 GO:0035459 cargo loading into vesicle(GO:0035459)
0.1 0.9 GO:0045842 positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.1 0.8 GO:0016188 synaptic vesicle maturation(GO:0016188)
0.1 0.6 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.1 1.0 GO:0055117 regulation of cardiac muscle contraction(GO:0055117)
0.1 0.6 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.1 0.7 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.1 0.7 GO:0046146 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.1 0.9 GO:0000186 activation of MAPKK activity(GO:0000186)
0.1 1.1 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.1 1.5 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.1 0.8 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.1 0.9 GO:0007339 binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.1 1.2 GO:0010737 protein kinase A signaling(GO:0010737)
0.0 1.6 GO:0050821 protein stabilization(GO:0050821)
0.0 0.1 GO:0070228 B cell apoptotic process(GO:0001783) regulation of B cell apoptotic process(GO:0002902) regulation of lymphocyte apoptotic process(GO:0070228)
0.0 0.7 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.0 3.1 GO:0030917 midbrain-hindbrain boundary development(GO:0030917)
0.0 0.3 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 1.0 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0 1.3 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 0.7 GO:2000816 regulation of mitotic sister chromatid separation(GO:0010965) negative regulation of sister chromatid segregation(GO:0033046) negative regulation of mitotic sister chromatid segregation(GO:0033048) negative regulation of mitotic sister chromatid separation(GO:2000816)
0.0 1.1 GO:0009648 photoperiodism(GO:0009648)
0.0 0.1 GO:0001954 positive regulation of cell-matrix adhesion(GO:0001954)
0.0 0.3 GO:0071260 cellular response to mechanical stimulus(GO:0071260)
0.0 1.8 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.0 1.4 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.0 0.8 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 0.2 GO:0060753 mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.0 0.3 GO:0006336 DNA replication-independent nucleosome assembly(GO:0006336)
0.0 0.3 GO:0051382 kinetochore assembly(GO:0051382)
0.0 0.2 GO:0006032 chitin catabolic process(GO:0006032)
0.0 0.2 GO:0045670 regulation of osteoclast differentiation(GO:0045670)
0.0 1.6 GO:0015718 monocarboxylic acid transport(GO:0015718)
0.0 0.8 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.8 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 0.4 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.9 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.0 0.1 GO:0098787 mRNA cleavage involved in mRNA processing(GO:0098787) pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.0 0.6 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 1.2 GO:0051017 actin filament bundle assembly(GO:0051017)
0.0 1.8 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 0.4 GO:0009636 response to toxic substance(GO:0009636)
0.0 0.1 GO:0071340 skeletal muscle acetylcholine-gated channel clustering(GO:0071340)
0.0 1.0 GO:0030100 regulation of endocytosis(GO:0030100)
0.0 0.9 GO:0017148 negative regulation of translation(GO:0017148)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0031310 integral component of vacuolar membrane(GO:0031166) intrinsic component of vacuolar membrane(GO:0031310)
0.4 1.1 GO:1990879 CST complex(GO:1990879)
0.2 1.1 GO:1990513 CLOCK-BMAL transcription complex(GO:1990513)
0.1 1.3 GO:0031211 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.1 1.1 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.1 1.5 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.1 0.8 GO:0005675 holo TFIIH complex(GO:0005675)
0.1 0.4 GO:0042584 chromaffin granule membrane(GO:0042584)
0.1 0.2 GO:0034457 Mpp10 complex(GO:0034457)
0.1 0.9 GO:0070187 telosome(GO:0070187)
0.0 1.8 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.0 1.3 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 0.1 GO:0043202 vacuolar lumen(GO:0005775) lysosomal lumen(GO:0043202)
0.0 0.8 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.9 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.9 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 1.4 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 1.7 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 1.7 GO:0030141 secretory granule(GO:0030141)
0.0 0.3 GO:0044545 NSL complex(GO:0044545)
0.0 0.4 GO:0031594 neuromuscular junction(GO:0031594)
0.0 1.3 GO:0042734 presynaptic membrane(GO:0042734)
0.0 5.1 GO:0005730 nucleolus(GO:0005730)
0.0 1.0 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 1.0 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 1.2 GO:0030173 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.0 1.3 GO:0005741 mitochondrial outer membrane(GO:0005741)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.6 GO:0008386 cholesterol monooxygenase (side-chain-cleaving) activity(GO:0008386) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.3 1.8 GO:0008118 N-acetyllactosaminide alpha-2,3-sialyltransferase activity(GO:0008118)
0.3 0.8 GO:0015562 protein-transmembrane transporting ATPase activity(GO:0015462) efflux transmembrane transporter activity(GO:0015562)
0.2 1.1 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.2 0.8 GO:0031151 histone methyltransferase activity (H3-K79 specific)(GO:0031151)
0.2 1.0 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.2 1.1 GO:0030274 LIM domain binding(GO:0030274)
0.2 0.5 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.2 1.1 GO:0070888 E-box binding(GO:0070888)
0.1 1.6 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.1 1.7 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.1 1.3 GO:0035198 miRNA binding(GO:0035198)
0.1 0.9 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1 0.6 GO:0008486 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.1 1.7 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.1 1.1 GO:0043047 single-stranded telomeric DNA binding(GO:0043047) sequence-specific single stranded DNA binding(GO:0098847)
0.1 1.1 GO:0052812 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812)
0.1 0.7 GO:0036137 kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.1 1.0 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.1 0.7 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.1 1.0 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.1 0.7 GO:0016838 carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.1 1.2 GO:0002039 p53 binding(GO:0002039)
0.1 1.3 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 0.8 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.1 0.9 GO:0032190 acrosin binding(GO:0032190)
0.1 3.4 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.8 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.7 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.1 GO:0033897 ribonuclease T2 activity(GO:0033897)
0.0 1.8 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 0.9 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 0.3 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.3 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.0 4.2 GO:0042803 protein homodimerization activity(GO:0042803)
0.0 0.8 GO:0005112 Notch binding(GO:0005112)
0.0 1.1 GO:0003684 damaged DNA binding(GO:0003684)
0.0 0.6 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 1.4 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 1.4 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.9 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 2.4 GO:0019905 syntaxin binding(GO:0019905)
0.0 0.2 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 1.4 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 0.2 GO:0004568 chitinase activity(GO:0004568)
0.0 0.8 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.1 GO:0070259 tyrosyl-DNA phosphodiesterase activity(GO:0070259)
0.0 0.2 GO:0008422 beta-glucosidase activity(GO:0008422)
0.0 0.1 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.0 0.8 GO:0004527 exonuclease activity(GO:0004527)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1 1.1 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.1 0.4 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.5 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 1.4 PID AURORA B PATHWAY Aurora B signaling
0.0 0.7 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 1.1 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 1.4 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 0.9 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 0.6 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.3 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 2.0 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.0 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.2 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.6 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.1 1.4 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.1 1.7 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 0.7 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.1 1.1 REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.1 1.0 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1 0.6 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.1 0.9 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.1 0.7 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.1 1.1 REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.0 0.8 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.9 REACTOME PHOSPHORYLATION OF THE APC C Genes involved in Phosphorylation of the APC/C
0.0 1.7 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.7 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 1.0 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 1.5 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.3 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.7 REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX Genes involved in Activation of the pre-replicative complex
0.0 0.7 REACTOME APC C CDC20 MEDIATED DEGRADATION OF MITOTIC PROTEINS Genes involved in APC/C:Cdc20 mediated degradation of mitotic proteins
0.0 1.4 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.1 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.0 0.2 REACTOME FGFR LIGAND BINDING AND ACTIVATION Genes involved in FGFR ligand binding and activation
0.0 0.6 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.3 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells