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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for barhl1a+barhl1b

Z-value: 1.16

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Transcription factors associated with barhl1a+barhl1b

Gene Symbol Gene ID Gene Info
ENSDARG00000019013 BarH-like homeobox 1b
ENSDARG00000035508 BarH-like homeobox 1a
ENSDARG00000110061 BarH-like homeobox 1a
ENSDARG00000112355 BarH-like homeobox 1a
ENSDARG00000113145 BarH-like homeobox 1b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
barhl1bdr11_v1_chr21_-_17482465_17482465-0.571.3e-02Click!
barhl1adr11_v1_chr5_-_29750377_29750377-0.513.1e-02Click!

Activity profile of barhl1a+barhl1b motif

Sorted Z-values of barhl1a+barhl1b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr6_-_8362419 3.65 ENSDART00000142752
ENSDART00000135810
acid phosphatase 5a, tartrate resistant
chr2_-_17115256 2.95 ENSDART00000190488
PIF1 5'-to-3' DNA helicase homolog (S. cerevisiae)
chr20_-_49889111 2.67 ENSDART00000058858
kinesin family member 13Bb
chr14_+_32918172 2.64 ENSDART00000182867
ligand of numb-protein X 2b
chr23_-_44577885 2.42 ENSDART00000166654
si:ch73-160p18.4
chr14_+_32918484 2.31 ENSDART00000105721
ligand of numb-protein X 2b
chr19_-_874888 2.19 ENSDART00000007206
eomesodermin homolog a
chr16_-_34195002 2.15 ENSDART00000054026
regulator of chromosome condensation 1
chr3_+_43373867 1.86 ENSDART00000159455
ENSDART00000172425
zinc finger, AN1-type domain 2A
chr24_-_41797681 1.82 ENSDART00000169643
Rho GTPase activating protein 28
chr16_+_20055878 1.82 ENSDART00000146436
ankyrin repeat domain 28b
chr7_+_34236238 1.80 ENSDART00000052474
timeless interacting protein
chr1_+_19433004 1.79 ENSDART00000133959
clock circadian regulator b
chr12_+_22404108 1.76 ENSDART00000153055
high density lipoprotein binding protein b
chr4_+_20051478 1.75 ENSDART00000143642
late endosomal/lysosomal adaptor, MAPK and MTOR activator 4
chr14_-_46198373 1.74 ENSDART00000031640
ENSDART00000132966
zgc:113425
chr6_+_19948043 1.73 ENSDART00000182636
phosphoinositide-3-kinase, regulatory subunit 5
chr20_-_32148901 1.72 ENSDART00000153405
ENSDART00000048537
ENSDART00000152984
centrosomal protein 57, like 1
chr5_-_42180205 1.71 ENSDART00000145247
family with sequence similarity 222, member Ba
chr4_-_12477224 1.69 ENSDART00000027756
ENSDART00000182706
ENSDART00000127150
Rho guanine nucleotide exchange factor (GEF) 39
chr1_-_55116453 1.68 ENSDART00000142348
SERTA domain containing 2a
chr1_-_45320126 1.65 ENSDART00000133572
si:ch73-90k17.1
chr10_+_7703251 1.62 ENSDART00000165134
gamma-glutamyl carboxylase
chr19_-_5380770 1.62 ENSDART00000000221
keratin 91
chr2_-_32387441 1.61 ENSDART00000148202
upstream binding transcription factor, like
chr23_+_20431388 1.59 ENSDART00000132920
ENSDART00000102963
ENSDART00000109899
ENSDART00000140219
solute carrier family 35 (GDP-fucose transporter), member C2
chr1_+_52481332 1.58 ENSDART00000074231
claudin domain containing 1b
chr7_+_38260434 1.58 ENSDART00000052351
CTD nuclear envelope phosphatase 1 regulatory subunit 1
chr10_+_10386435 1.56 ENSDART00000179214
ENSDART00000189799
ENSDART00000193875
sarcosine dehydrogenase
chr12_+_14149686 1.54 ENSDART00000123741
kelch repeat and BTB (POZ) domain containing 2
chr20_-_38827623 1.54 ENSDART00000153310
carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
chr19_-_11315224 1.54 ENSDART00000104933
endonuclease/exonuclease/phosphatase family domain containing 1
chr13_+_22717939 1.51 ENSDART00000188288
nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
chr16_+_20056030 1.47 ENSDART00000027020
ankyrin repeat domain 28b
chr22_-_10541372 1.45 ENSDART00000179708
si:dkey-42i9.4
chr5_+_52596850 1.45 ENSDART00000162022
protein prenyltransferase alpha subunit repeat containing 1
chr23_-_17509656 1.43 ENSDART00000148423
DnaJ (Hsp40) homolog, subfamily C, member 5ab
chr7_+_36467796 1.43 ENSDART00000146202
akt interacting protein
chr13_+_6189203 1.42 ENSDART00000109665
protein phosphatase, Mg2+/Mn2+ dependent, 1G
chr20_-_30938184 1.41 ENSDART00000147359
ENSDART00000062552
WT1 associated protein
chr19_-_47571456 1.37 ENSDART00000158071
ENSDART00000165841
ribonucleotide reductase M2 polypeptide
chr14_+_8947282 1.37 ENSDART00000047993
ribosomal protein S6 kinase a, like
chr8_+_3431671 1.36 ENSDART00000017850
cytosolic thiouridylase subunit 1 homolog (S. pombe)
chr10_-_35257458 1.35 ENSDART00000143890
ENSDART00000139107
ENSDART00000082445
proline rich 11
chr25_+_753364 1.35 ENSDART00000183804
twinfilin actin binding protein 1
chr13_+_9368621 1.34 ENSDART00000109126
Alstrom syndrome protein 1
chr3_+_35005730 1.33 ENSDART00000029451
protein kinase C, beta b
chr9_+_500052 1.33 ENSDART00000166707

chr25_-_24202576 1.32 ENSDART00000048507
UEV and lactate/malate dehyrogenase domains
chr6_-_42336987 1.31 ENSDART00000128777
ENSDART00000075601
Fanconi anemia, complementation group D2
chr24_+_24726956 1.30 ENSDART00000144574
ENSDART00000066628
mitochondrial fission regulator 1
chr22_+_11756040 1.30 ENSDART00000105808
keratin 97
chr7_+_24645186 1.30 ENSDART00000150118
ENSDART00000150233
ENSDART00000087691
glucosidase, beta (bile acid) 2
chr14_+_50937757 1.29 ENSDART00000163865
ring finger protein 44
chr12_-_20409794 1.28 ENSDART00000077936
leucine carboxyl methyltransferase 1
chr20_-_34801181 1.27 ENSDART00000048375
ENSDART00000132426
stathmin-like 4
chr1_+_44173506 1.26 ENSDART00000170512
catenin (cadherin-associated protein), delta 1
chr3_+_22035863 1.25 ENSDART00000177169
cell division cycle 27
chr8_-_16674584 1.25 ENSDART00000100727
oxysterol binding protein-like 9
chr7_-_24112484 1.24 ENSDART00000111923
ajuba LIM protein
chr17_-_31819837 1.23 ENSDART00000160281
abraxas 2b, BRISC complex subunit
chr17_+_22311413 1.22 ENSDART00000151929
solute carrier family 8 (sodium/calcium exchanger), member 1b
chr1_-_24349759 1.21 ENSDART00000142740
ENSDART00000177989
LPS-responsive vesicle trafficking, beach and anchor containing
chr2_-_40890264 1.20 ENSDART00000123886
UDP-glucose glycoprotein glucosyltransferase 1
chr2_-_40890004 1.20 ENSDART00000191746
UDP-glucose glycoprotein glucosyltransferase 1
chr5_+_24087035 1.20 ENSDART00000183644
tumor protein p53
chr3_-_36210344 1.19 ENSDART00000025326
casein kinase 1, delta a
chr7_-_31921687 1.19 ENSDART00000146720
lin-7 homolog C (C. elegans)
chr17_-_33414781 1.18 ENSDART00000142203
ENSDART00000034638
coiled-coil domain containing 28A
chr23_-_10722664 1.18 ENSDART00000146526
ENSDART00000129022
ENSDART00000104985
forkhead box P1a
chr7_+_32901658 1.17 ENSDART00000115420
anoctamin 9b
chr19_+_29808471 1.16 ENSDART00000186428
histone deacetylase 1
chr3_+_22036113 1.15 ENSDART00000132190
cell division cycle 27
chr3_+_32791786 1.15 ENSDART00000180174
TBC1 domain family, member 10b
chr25_-_7918526 1.12 ENSDART00000104686
ENSDART00000156761
autophagy/beclin-1 regulator 1b
chr13_-_35907768 1.10 ENSDART00000147522
MYCL proto-oncogene, bHLH transcription factor a
chr18_+_45666489 1.10 ENSDART00000180147
ENSDART00000151351
proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
chr15_+_24756860 1.10 ENSDART00000156424
ENSDART00000078035
carboxypeptidase D, a
chr5_-_35252761 1.10 ENSDART00000051278
transportin 1
chr13_+_6188759 1.09 ENSDART00000161062
protein phosphatase, Mg2+/Mn2+ dependent, 1G
chr3_+_22036391 1.08 ENSDART00000147721
cell division cycle 27
chr1_+_53321878 1.08 ENSDART00000143909
TBC1 domain family, member 9 (with GRAM domain)
chr11_+_11719575 1.07 ENSDART00000003891
junction plakoglobin a
chr17_+_30591287 1.07 ENSDART00000154243
si:dkey-190l8.2
chr4_+_73051901 1.06 ENSDART00000174219
zgc:152938
chr2_+_49457449 1.06 ENSDART00000185470
SH3-domain GRB2-like 1a
chr6_+_296130 1.05 ENSDART00000073985
RNA binding fox-1 homolog 2
chr2_-_29923403 1.04 ENSDART00000144672
PAX interacting (with transcription-activation domain) protein 1
chr13_+_46718518 1.04 ENSDART00000160401
ENSDART00000182884
transmembrane protein 63Ba
chr8_-_25761544 1.03 ENSDART00000078152
suppressor of variegation 3-9 homolog 1b
chr2_-_40889465 1.03 ENSDART00000192631
ENSDART00000180824
UDP-glucose glycoprotein glucosyltransferase 1
chr13_-_33227411 1.02 ENSDART00000057386
golgin A5
chr14_+_26247319 1.02 ENSDART00000192793
coiled-coil domain containing 69
chr7_+_25000060 1.02 ENSDART00000039265
ENSDART00000141814
N(alpha)-acetyltransferase 40, NatD catalytic subunit, homolog (S. cerevisiae)
chr13_-_35908275 1.00 ENSDART00000013961
MYCL proto-oncogene, bHLH transcription factor a
chr22_+_34701848 0.99 ENSDART00000082066
ATPase H+ transporting V0 subunit e2
chr7_-_55633475 0.99 ENSDART00000149478
galactosamine (N-acetyl)-6-sulfatase
chr5_-_26247973 0.99 ENSDART00000098527
endoplasmic reticulum aminopeptidase 1b
chr4_-_75172216 0.99 ENSDART00000127522
N(alpha)-acetyltransferase 40, NatD catalytic subunit, homolog (S. cerevisiae)
chr18_-_38271298 0.99 ENSDART00000143016
cell cycle associated protein 1b
chr11_+_25693395 0.98 ENSDART00000110224
MON1 secretory trafficking family member Bb
chr22_+_28236737 0.97 ENSDART00000086868
SUMO1/sentrin specific peptidase 7b
chr5_+_53580846 0.96 ENSDART00000184967
ENSDART00000161751
TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr4_-_9350585 0.96 ENSDART00000148155
si:ch211-125a15.1
chr12_+_16087077 0.96 ENSDART00000141898
zinc finger protein 281b
chr17_+_33415319 0.95 ENSDART00000140805
ENSDART00000025501
ENSDART00000146447
synaptosomal-associated protein 23.1
chr5_+_57480014 0.95 ENSDART00000135520
si:ch211-202f5.3
chr23_-_17859619 0.95 ENSDART00000178248
tuftelin interacting protein 11
chr7_+_25126629 0.95 ENSDART00000077217
zgc:101765
chr25_-_3745393 0.95 ENSDART00000037973
MORC family CW-type zinc finger 2
chr15_-_17138640 0.95 ENSDART00000080777
mitochondrial ribosomal protein L28
chr15_-_14193659 0.94 ENSDART00000171197
polynucleotide kinase 3'-phosphatase
chr15_-_14193926 0.93 ENSDART00000162707
polynucleotide kinase 3'-phosphatase
chr17_+_24445818 0.93 ENSDART00000139963
UDP-glucose pyrophosphorylase 2b
chr9_+_8968702 0.92 ENSDART00000008490
ubiquitin conjugating enzyme E2 A, like
chr13_+_7387822 0.92 ENSDART00000148240
exocyst complex component 3-like 4
chr19_+_2685779 0.92 ENSDART00000160533
ENSDART00000097531
translocase of outer mitochondrial membrane 7 homolog (yeast)
chr5_-_26247671 0.92 ENSDART00000145187
endoplasmic reticulum aminopeptidase 1b
chr11_-_25461336 0.91 ENSDART00000014945
host cell factor C1a
chr11_-_34232906 0.91 ENSDART00000162150
large 60S subunit nuclear export GTPase 1
chr1_-_31516091 0.91 ENSDART00000139828
ENSDART00000146567
centromere protein K
chr10_+_34001444 0.90 ENSDART00000149934
klotho
chr17_+_24446353 0.90 ENSDART00000140467
UDP-glucose pyrophosphorylase 2b
chr10_+_15967341 0.90 ENSDART00000115130
ENSDART00000189687
amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
chr2_-_37103622 0.89 ENSDART00000137849
zgc:101744
chr21_-_30181268 0.89 ENSDART00000167867
heterogeneous nuclear ribonucleoprotein H1, like
chr16_-_31824525 0.89 ENSDART00000058737
cell division cycle 42, like
chr5_-_32505276 0.89 ENSDART00000034705
ENSDART00000187597
N-terminal Xaa-Pro-Lys N-methyltransferase 1
chr13_-_35808904 0.86 ENSDART00000171667
mitogen-activated protein kinase kinase kinase 4
chr2_-_32826108 0.86 ENSDART00000098834
pre-mRNA processing factor 4Ba
chr1_-_31515746 0.85 ENSDART00000190886
centromere protein K
chr21_-_30181732 0.85 ENSDART00000015636
heterogeneous nuclear ribonucleoprotein H1, like
chr19_-_12967986 0.85 ENSDART00000151064
solute carrier family 25 (mitochondrial folate carrier), member 32a
chr5_-_69620722 0.85 ENSDART00000097248
aldehyde dehydrogenase 2 family (mitochondrial), tandem duplicate 2
chr17_+_30843881 0.84 ENSDART00000149600
ENSDART00000148547
tripeptidyl peptidase I
chr5_+_51833132 0.84 ENSDART00000167491
PAP associated domain containing 4
chr14_+_5835134 0.84 ENSDART00000054867
ancient ubiquitous protein 1
chr3_+_27642081 0.83 ENSDART00000055500
pentraxin 4, long
chr5_+_8196264 0.82 ENSDART00000174564
ENSDART00000161261
LMBR1 domain containing 2a
chr25_-_20666328 0.82 ENSDART00000098076
C-terminal Src kinase
chr10_+_8847033 0.82 ENSDART00000140894
integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor), tandem duplicate 1
chr15_-_19128705 0.81 ENSDART00000152428
Rho GTPase activating protein 32a
chr17_+_24446533 0.81 ENSDART00000131417
UDP-glucose pyrophosphorylase 2b
chr2_-_32825917 0.81 ENSDART00000180409
pre-mRNA processing factor 4Ba
chr5_+_20255568 0.81 ENSDART00000153643
slingshot protein phosphatase 1a
chr3_-_15352303 0.80 ENSDART00000104338
ENSDART00000145919
ENSDART00000132135
phosphatidylinositol transfer protein, beta, like
chr19_-_20777351 0.80 ENSDART00000019206
N-glycanase 1
chr7_-_7764287 0.80 ENSDART00000173021
ENSDART00000113131
inturned planar cell polarity protein
chr14_+_21820034 0.79 ENSDART00000122739
C-terminal binding protein 1
chr15_-_23721618 0.78 ENSDART00000109318
zinc finger CCCH-type containing 4
chr16_-_20870143 0.78 ENSDART00000169541
ENSDART00000040727
Tax1 (human T-cell leukemia virus type I) binding protein 1b
chr22_+_786556 0.78 ENSDART00000125347
cryptochrome circadian clock 1bb
chr3_+_24050043 0.78 ENSDART00000151788
chromobox homolog 1a (HP1 beta homolog Drosophila)
chr14_+_1170968 0.77 ENSDART00000125203
ENSDART00000193575
HOP homeobox
chr21_+_37090795 0.76 ENSDART00000085786
zinc finger protein 346
chr5_-_28915130 0.76 ENSDART00000078592
neural proliferation, differentiation and control, 1b
chr3_+_31093455 0.76 ENSDART00000153074
si:dkey-66i24.9
chr4_-_73488406 0.76 ENSDART00000115002
si:ch73-266f23.1
chr21_-_33478164 0.76 ENSDART00000191542
si:ch73-42p12.2
chr17_+_24597001 0.75 ENSDART00000191834
rearranged L-myc fusion
chr8_-_44223899 0.75 ENSDART00000143020
syntaxin 2b
chr19_+_46237665 0.75 ENSDART00000159391
vacuolar protein sorting 28 (yeast)
chr16_+_26732086 0.75 ENSDART00000138496
RAD54 homolog B (S. cerevisiae)
chr19_+_15444210 0.74 ENSDART00000142509
lin-28 homolog A (C. elegans)
chr21_-_2162850 0.74 ENSDART00000159731
expressed sequence AI877918
chr4_+_15006217 0.74 ENSDART00000090837
zinc finger, C3HC-type containing 1
chr17_+_50657509 0.72 ENSDART00000179957
DDHD domain containing 1a
chr14_-_14705335 0.71 ENSDART00000157392
ENSDART00000159456
O-linked N-acetylglucosamine (GlcNAc) transferase, tandem duplicate 1
chr14_+_21755469 0.70 ENSDART00000186326
lysine (K)-specific demethylase 2Ab
chr16_-_31475904 0.70 ENSDART00000145691
si:ch211-251p5.5
chr4_-_18841071 0.70 ENSDART00000140722
Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase
chr3_-_20106233 0.70 ENSDART00000145285
selenoprotein W, 2b
chr3_-_147368 0.69 ENSDART00000159073

chr15_-_41689684 0.69 ENSDART00000143447
splA/ryanodine receptor domain and SOCS box containing 4b
chr3_+_13842554 0.69 ENSDART00000162317
ENSDART00000158068
interleukin enhancer binding factor 3b
chr2_+_307665 0.69 ENSDART00000082083
zgc:113452
chr7_-_49637278 0.69 ENSDART00000011456
tumor susceptibility 101b
chr10_-_25543227 0.69 ENSDART00000007778
glutamate receptor, ionotropic, kainate 1a
chr15_-_34878388 0.68 ENSDART00000154094
mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase a
chr5_-_22082918 0.68 ENSDART00000020908
zinc finger, C4H2 domain containing
chr3_-_27868183 0.67 ENSDART00000185812
4-aminobutyrate aminotransferase
chr21_+_27302752 0.67 ENSDART00000012855
SART1, U4/U6.U5 tri-snRNP-associated protein 1
chr17_+_43926523 0.67 ENSDART00000121550
ENSDART00000041447
kinectin 1
chr13_+_15656042 0.67 ENSDART00000134240
MAP/microtubule affinity-regulating kinase 3a
chr8_-_44223473 0.66 ENSDART00000098525
syntaxin 2b
chr5_-_32505109 0.65 ENSDART00000188219
N-terminal Xaa-Pro-Lys N-methyltransferase 1
chr25_+_17590095 0.63 ENSDART00000009767
vac14 homolog (S. cerevisiae)
chr10_-_8956973 0.63 ENSDART00000189564
molybdenum cofactor synthesis 2
chr17_-_17759138 0.62 ENSDART00000157128
ENSDART00000123845
aarF domain containing kinase 1
chr18_+_29898955 0.61 ENSDART00000064080
centromere protein N
chr23_-_25779995 0.61 ENSDART00000110670
si:dkey-21c19.3
chr12_-_19119176 0.61 ENSDART00000149180
aconitase 2, mitochondrial
chr16_+_53387085 0.61 ENSDART00000154223
ENSDART00000101404
kinesin family member 13A
chr3_+_45364849 0.60 ENSDART00000153974
ubiquitin-conjugating enzyme E2Ia
chr24_-_20599781 0.59 ENSDART00000179664
ENSDART00000141823
zinc finger and BTB domain containing 47b
chr4_-_4751981 0.59 ENSDART00000147436
ENSDART00000092984
ENSDART00000158466
cAMP responsive element binding protein 3-like 2
chr21_+_25801345 0.58 ENSDART00000035062
neurofibromin 2b (merlin)
chr6_-_55309190 0.58 ENSDART00000162117
ubiquitin-conjugating enzyme E2C
chr12_-_13318944 0.58 ENSDART00000152201
ENSDART00000041394
ER membrane protein complex subunit 9
chr20_-_54924593 0.58 ENSDART00000151522
si:dkey-15f23.1

Network of associatons between targets according to the STRING database.

First level regulatory network of barhl1a+barhl1b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.2 GO:0055109 invagination involved in gastrulation with mouth forming second(GO:0055109) morphogenesis of an epithelial fold(GO:0060571)
0.5 2.6 GO:0006011 UDP-glucose metabolic process(GO:0006011)
0.5 1.6 GO:1901052 sarcosine metabolic process(GO:1901052)
0.5 2.6 GO:0006978 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978) DNA damage response, signal transduction resulting in transcription(GO:0042772)
0.5 1.5 GO:0021563 glossopharyngeal nerve development(GO:0021563)
0.5 1.5 GO:0006480 N-terminal protein amino acid methylation(GO:0006480)
0.4 1.3 GO:0006678 glucosylceramide metabolic process(GO:0006678)
0.4 1.2 GO:2000637 negative regulation of hippo signaling(GO:0035331) positive regulation of posttranscriptional gene silencing(GO:0060148) positive regulation of gene silencing by miRNA(GO:2000637)
0.4 1.8 GO:0043111 replication fork arrest(GO:0043111)
0.3 3.7 GO:0045453 bone resorption(GO:0045453)
0.3 3.3 GO:0072386 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.3 1.0 GO:0000390 spliceosomal complex disassembly(GO:0000390)
0.3 1.6 GO:0010867 regulation of triglyceride biosynthetic process(GO:0010866) positive regulation of triglyceride biosynthetic process(GO:0010867)
0.3 2.1 GO:1901673 regulation of mitotic spindle assembly(GO:1901673)
0.3 3.5 GO:1902101 positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.3 1.6 GO:0018214 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.3 1.3 GO:0044342 type B pancreatic cell proliferation(GO:0044342)
0.3 4.3 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.3 1.1 GO:0036306 embryonic heart tube elongation(GO:0036306)
0.3 3.2 GO:0000002 mitochondrial genome maintenance(GO:0000002)
0.3 1.3 GO:1990918 double-strand break repair involved in meiotic recombination(GO:1990918)
0.2 1.2 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.2 1.4 GO:0080009 mRNA methylation(GO:0080009)
0.2 1.4 GO:0002143 tRNA wobble position uridine thiolation(GO:0002143) protein urmylation(GO:0032447)
0.2 1.1 GO:0097272 ammonia homeostasis(GO:0097272)
0.2 1.1 GO:0002159 desmosome assembly(GO:0002159)
0.2 0.6 GO:0070278 extracellular matrix constituent secretion(GO:0070278)
0.2 0.6 GO:0030521 androgen receptor signaling pathway(GO:0030521) regulation of androgen receptor signaling pathway(GO:0060765)
0.2 0.6 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.2 1.9 GO:0019883 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous antigen(GO:0019883) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.2 1.2 GO:0033687 osteoblast proliferation(GO:0033687)
0.2 0.8 GO:0060368 regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060368)
0.1 2.4 GO:0051382 kinetochore assembly(GO:0051382)
0.1 2.0 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.1 4.9 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.1 0.7 GO:0009450 gamma-aminobutyric acid catabolic process(GO:0009450)
0.1 1.6 GO:0016926 protein desumoylation(GO:0016926)
0.1 1.3 GO:0018342 protein prenylation(GO:0018342) prenylation(GO:0097354)
0.1 1.2 GO:0061588 calcium activated phospholipid scrambling(GO:0061588)
0.1 0.4 GO:0044205 'de novo' UMP biosynthetic process(GO:0044205)
0.1 1.4 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.1 0.4 GO:0090266 regulation of spindle checkpoint(GO:0090231) regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.1 0.7 GO:0010269 response to selenium ion(GO:0010269)
0.1 1.3 GO:0018410 C-terminal protein amino acid modification(GO:0018410)
0.1 0.3 GO:2000009 regulation of protein localization to cell surface(GO:2000008) negative regulation of protein localization to cell surface(GO:2000009)
0.1 1.7 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.1 0.1 GO:0042144 vacuole fusion, non-autophagic(GO:0042144)
0.1 0.5 GO:2000389 neutrophil extravasation(GO:0072672) regulation of neutrophil extravasation(GO:2000389) positive regulation of neutrophil extravasation(GO:2000391)
0.1 1.8 GO:0051098 regulation of binding(GO:0051098)
0.1 0.4 GO:0006272 leading strand elongation(GO:0006272)
0.1 0.3 GO:0071514 genetic imprinting(GO:0071514)
0.1 1.4 GO:0045022 early endosome to late endosome transport(GO:0045022) vesicle-mediated transport between endosomal compartments(GO:0098927)
0.1 0.9 GO:0051601 exocyst localization(GO:0051601)
0.1 0.3 GO:0006404 RNA import into nucleus(GO:0006404) snRNA import into nucleus(GO:0061015)
0.1 0.7 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.1 0.7 GO:0032488 Cdc42 protein signal transduction(GO:0032488)
0.1 0.8 GO:0006517 protein deglycosylation(GO:0006517)
0.1 0.5 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.1 2.7 GO:0061462 protein localization to lysosome(GO:0061462)
0.1 0.6 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.1 0.6 GO:0043545 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.1 0.2 GO:0042256 mature ribosome assembly(GO:0042256) assembly of large subunit precursor of preribosome(GO:1902626)
0.1 2.4 GO:0031629 synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.1 2.2 GO:0009648 photoperiodism(GO:0009648)
0.1 1.2 GO:0098703 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.1 1.3 GO:0008078 mesodermal cell migration(GO:0008078)
0.1 0.2 GO:0034433 steroid esterification(GO:0034433) sterol esterification(GO:0034434) cholesterol esterification(GO:0034435)
0.1 0.9 GO:0000054 ribosomal subunit export from nucleus(GO:0000054) ribosome localization(GO:0033750) establishment of ribosome localization(GO:0033753) rRNA-containing ribonucleoprotein complex export from nucleus(GO:0071428)
0.1 0.5 GO:1901099 histone dephosphorylation(GO:0016576) negative regulation of signal transduction in absence of ligand(GO:1901099) regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001239) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.1 0.8 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.1 0.2 GO:0006297 nucleotide-excision repair, DNA gap filling(GO:0006297)
0.1 1.2 GO:0042752 regulation of circadian rhythm(GO:0042752)
0.1 0.9 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 1.5 GO:0042632 cholesterol homeostasis(GO:0042632) sterol homeostasis(GO:0055092)
0.0 0.2 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.2 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.0 0.4 GO:0021521 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573) embryonic skeletal joint development(GO:0072498)
0.0 1.6 GO:0000266 mitochondrial fission(GO:0000266)
0.0 0.7 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 1.0 GO:0006623 protein targeting to vacuole(GO:0006623)
0.0 1.1 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.2 GO:0031571 mitotic G1 DNA damage checkpoint(GO:0031571)
0.0 0.9 GO:0007568 aging(GO:0007568)
0.0 0.8 GO:0060173 limb development(GO:0060173)
0.0 1.4 GO:0007050 cell cycle arrest(GO:0007050)
0.0 0.3 GO:0031274 pseudopodium organization(GO:0031268) pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.7 GO:0048665 neuron fate specification(GO:0048665)
0.0 1.3 GO:0007019 microtubule depolymerization(GO:0007019)
0.0 0.1 GO:0090646 mitochondrial tRNA processing(GO:0090646)
0.0 1.3 GO:0050853 B cell receptor signaling pathway(GO:0050853)
0.0 0.5 GO:0048263 determination of dorsal identity(GO:0048263)
0.0 1.7 GO:0043406 positive regulation of MAP kinase activity(GO:0043406)
0.0 0.1 GO:0018171 peptidyl-cysteine oxidation(GO:0018171)
0.0 0.4 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.0 0.7 GO:0006493 protein O-linked glycosylation(GO:0006493)
0.0 0.2 GO:0071459 protein localization to kinetochore(GO:0034501) protein localization to chromosome, centromeric region(GO:0071459)
0.0 0.1 GO:0071405 response to methanol(GO:0033986) cellular response to methanol(GO:0071405)
0.0 1.0 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0 1.9 GO:0046939 nucleotide phosphorylation(GO:0046939)
0.0 0.7 GO:0006482 protein demethylation(GO:0006482) protein dealkylation(GO:0008214)
0.0 0.2 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.0 0.8 GO:0071875 adrenergic receptor signaling pathway(GO:0071875)
0.0 1.6 GO:0048741 myotube cell development(GO:0014904) skeletal muscle fiber development(GO:0048741)
0.0 2.5 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 0.2 GO:0070189 kynurenine metabolic process(GO:0070189)
0.0 0.3 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.0 0.4 GO:0038034 signal transduction in absence of ligand(GO:0038034) extrinsic apoptotic signaling pathway in absence of ligand(GO:0097192)
0.0 0.6 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.0 1.0 GO:0034968 histone lysine methylation(GO:0034968)
0.0 0.2 GO:0006450 regulation of translational fidelity(GO:0006450)
0.0 0.2 GO:0060753 mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.0 0.1 GO:0048532 anatomical structure arrangement(GO:0048532)
0.0 0.5 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.0 0.1 GO:0046457 prostaglandin biosynthetic process(GO:0001516) prostanoid biosynthetic process(GO:0046457)
0.0 0.6 GO:0055088 lipid homeostasis(GO:0055088)
0.0 0.5 GO:0043966 histone H3 acetylation(GO:0043966)
0.0 1.5 GO:0008285 negative regulation of cell proliferation(GO:0008285)
0.0 0.8 GO:0015914 phospholipid transport(GO:0015914)
0.0 0.8 GO:0006661 phosphatidylinositol biosynthetic process(GO:0006661)
0.0 2.1 GO:0043484 regulation of RNA splicing(GO:0043484)
0.0 0.2 GO:0051897 positive regulation of protein kinase B signaling(GO:0051897)
0.0 0.8 GO:0042493 response to drug(GO:0042493)
0.0 0.1 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.0 2.0 GO:0000209 protein polyubiquitination(GO:0000209)
0.0 0.8 GO:0018210 peptidyl-threonine phosphorylation(GO:0018107) peptidyl-threonine modification(GO:0018210)
0.0 0.3 GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage(GO:0008630)
0.0 0.4 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 0.6 GO:0035304 regulation of protein dephosphorylation(GO:0035304)
0.0 0.2 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 1.0 GO:0034249 negative regulation of translation(GO:0017148) negative regulation of cellular amide metabolic process(GO:0034249)
0.0 0.3 GO:0043631 mRNA polyadenylation(GO:0006378) RNA polyadenylation(GO:0043631)
0.0 0.7 GO:0051607 defense response to virus(GO:0051607)
0.0 1.1 GO:0030335 positive regulation of cell migration(GO:0030335)
0.0 0.5 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.8 GO:0000941 condensed nuclear chromosome inner kinetochore(GO:0000941)
0.4 2.2 GO:1990513 CLOCK-BMAL transcription complex(GO:1990513)
0.4 1.8 GO:0031298 replication fork protection complex(GO:0031298)
0.4 1.4 GO:0045293 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.3 1.6 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.3 1.2 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.3 1.7 GO:0071986 Ragulator complex(GO:0071986)
0.3 1.0 GO:0046695 SLIK (SAGA-like) complex(GO:0046695)
0.2 1.4 GO:0070695 FHF complex(GO:0070695)
0.2 0.6 GO:0033065 Rad51C-XRCC3 complex(GO:0033065)
0.2 0.9 GO:0033503 HULC complex(GO:0033503)
0.2 0.8 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.1 1.9 GO:0097651 phosphatidylinositol 3-kinase complex, class IB(GO:0005944) phosphatidylinositol 3-kinase complex, class I(GO:0097651)
0.1 0.5 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.1 0.8 GO:0001650 fibrillar center(GO:0001650)
0.1 0.6 GO:0019008 molybdopterin synthase complex(GO:0019008)
0.1 2.9 GO:0005680 anaphase-promoting complex(GO:0005680)
0.1 0.4 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.1 0.9 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.1 1.5 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.1 0.6 GO:0000306 extrinsic component of vacuolar membrane(GO:0000306) phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.1 0.4 GO:0033061 DNA recombinase mediator complex(GO:0033061)
0.1 2.7 GO:0005657 replication fork(GO:0005657)
0.1 1.0 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.1 0.2 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.1 1.4 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.1 1.1 GO:0030057 desmosome(GO:0030057)
0.1 3.1 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.1 0.6 GO:0072546 ER membrane protein complex(GO:0072546)
0.1 0.2 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.1 0.9 GO:0015030 Cajal body(GO:0015030)
0.1 0.2 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.0 0.7 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.5 GO:0000124 SAGA complex(GO:0000124)
0.0 3.3 GO:0005871 kinesin complex(GO:0005871)
0.0 0.9 GO:0000145 exocyst(GO:0000145)
0.0 0.4 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.0 0.2 GO:0005784 Sec61 translocon complex(GO:0005784)
0.0 1.2 GO:0005876 spindle microtubule(GO:0005876)
0.0 0.7 GO:0046540 U4/U6 x U5 tri-snRNP complex(GO:0046540)
0.0 2.9 GO:0005882 intermediate filament(GO:0005882)
0.0 0.2 GO:0071546 pi-body(GO:0071546)
0.0 0.4 GO:0000815 ESCRT III complex(GO:0000815)
0.0 1.0 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.1 GO:0033263 CORVET complex(GO:0033263)
0.0 0.4 GO:0071010 U2-type prespliceosome(GO:0071004) prespliceosome(GO:0071010)
0.0 0.3 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 1.3 GO:0000793 condensed chromosome(GO:0000793)
0.0 0.5 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.9 GO:0030496 midbody(GO:0030496)
0.0 1.6 GO:0000775 chromosome, centromeric region(GO:0000775)
0.0 1.0 GO:0031985 Golgi cisterna(GO:0031985)
0.0 0.8 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.6 GO:0005901 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.0 0.2 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 3.4 GO:0003980 UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980)
0.6 1.9 GO:0046403 polynucleotide 3'-phosphatase activity(GO:0046403)
0.6 2.9 GO:0043139 5'-3' DNA helicase activity(GO:0043139)
0.5 2.6 GO:0004088 carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.5 2.6 GO:0003983 UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
0.5 1.5 GO:0071885 N-terminal protein N-methyltransferase activity(GO:0071885)
0.5 2.0 GO:0043998 H2A histone acetyltransferase activity(GO:0043998)
0.5 3.7 GO:0003993 acid phosphatase activity(GO:0003993)
0.4 1.6 GO:0008488 gamma-glutamyl carboxylase activity(GO:0008488)
0.4 1.6 GO:0046997 oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor(GO:0046997)
0.3 1.3 GO:0070182 DNA polymerase binding(GO:0070182)
0.3 2.3 GO:0070888 E-box binding(GO:0070888)
0.3 1.2 GO:0097016 L27 domain binding(GO:0097016)
0.3 0.8 GO:0008517 folic acid transporter activity(GO:0008517)
0.3 1.1 GO:0061656 SUMO conjugating enzyme activity(GO:0061656)
0.2 0.6 GO:0003994 aconitate hydratase activity(GO:0003994)
0.2 1.4 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.2 1.3 GO:0035173 histone kinase activity(GO:0035173)
0.2 2.2 GO:0008422 beta-glucosidase activity(GO:0008422)
0.2 0.7 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.2 0.6 GO:0030366 molybdopterin synthase activity(GO:0030366)
0.2 2.5 GO:0004724 magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
0.1 0.4 GO:0047804 cysteine-S-conjugate beta-lyase activity(GO:0047804)
0.1 1.3 GO:0010340 carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
0.1 1.3 GO:0008318 protein prenyltransferase activity(GO:0008318)
0.1 0.4 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.1 0.5 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1 1.0 GO:0070137 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.1 1.1 GO:0045294 alpha-catenin binding(GO:0045294)
0.1 0.7 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262) protein O-GlcNAc transferase activity(GO:0097363)
0.1 0.6 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.1 1.4 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.1 1.0 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.1 0.8 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.1 0.6 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.1 1.7 GO:0043015 gamma-tubulin binding(GO:0043015)
0.1 1.2 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.1 0.4 GO:0017020 myosin phosphatase regulator activity(GO:0017020)
0.1 0.4 GO:0016635 oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.1 1.2 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.1 0.5 GO:0015616 DNA translocase activity(GO:0015616)
0.1 1.2 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.1 0.6 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.1 0.3 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.1 1.4 GO:0016251 obsolete general RNA polymerase II transcription factor activity(GO:0016251)
0.1 1.2 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.1 0.7 GO:0017091 AU-rich element binding(GO:0017091) mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.1 1.1 GO:0061608 nuclear import signal receptor activity(GO:0061608)
0.1 0.2 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.1 0.8 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.1 1.9 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.1 1.6 GO:0015248 sterol transporter activity(GO:0015248)
0.1 0.2 GO:0034736 sterol O-acyltransferase activity(GO:0004772) cholesterol O-acyltransferase activity(GO:0034736)
0.1 1.2 GO:0050321 tau-protein kinase activity(GO:0050321)
0.1 1.7 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.3 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0 0.4 GO:0043035 chromatin insulator sequence binding(GO:0043035)
0.0 0.1 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.0 0.1 GO:0071568 UFM1 transferase activity(GO:0071568)
0.0 0.6 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 0.9 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.2 GO:0043295 glutathione binding(GO:0043295)
0.0 0.1 GO:0052905 tRNA (guanine(9)-N(1))-methyltransferase activity(GO:0052905)
0.0 1.7 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.2 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.6 GO:0035497 cAMP response element binding(GO:0035497)
0.0 1.3 GO:0000049 tRNA binding(GO:0000049)
0.0 0.6 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.7 GO:0019894 kinesin binding(GO:0019894)
0.0 0.9 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.0 0.2 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.0 0.6 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.7 GO:1904315 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0 1.4 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 2.0 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.2 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 0.2 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 0.8 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 0.9 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 0.4 GO:0031267 small GTPase binding(GO:0031267)
0.0 2.1 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor(GO:0016616)
0.0 0.4 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 4.8 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 0.1 GO:0016972 thiol oxidase activity(GO:0016972)
0.0 4.3 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.3 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.0 0.2 GO:0022884 protein transmembrane transporter activity(GO:0008320) macromolecule transmembrane transporter activity(GO:0022884)
0.0 1.0 GO:0045296 cadherin binding(GO:0045296)
0.0 0.8 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 2.7 GO:0003682 chromatin binding(GO:0003682)
0.0 1.3 GO:0003713 transcription coactivator activity(GO:0003713)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.4 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.1 1.5 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.1 2.0 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.1 3.4 PID ATR PATHWAY ATR signaling pathway
0.1 4.5 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.1 1.9 PID EPHA FWDPATHWAY EPHA forward signaling
0.1 0.8 PID ATM PATHWAY ATM pathway
0.1 2.8 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.1 2.9 PID TELOMERASE PATHWAY Regulation of Telomerase
0.1 2.3 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.0 0.2 ST JAK STAT PATHWAY Jak-STAT Pathway
0.0 0.9 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.6 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 0.9 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.1 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.2 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.5 PID REG GR PATHWAY Glucocorticoid receptor regulatory network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.4 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.2 1.6 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.2 4.1 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.2 1.6 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.2 0.8 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.1 1.2 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.1 2.3 REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.1 2.4 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.1 1.8 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.1 1.5 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.1 1.1 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.1 0.7 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.1 1.4 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.1 1.2 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.1 0.6 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.7 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 0.6 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.9 REACTOME FGFR LIGAND BINDING AND ACTIVATION Genes involved in FGFR ligand binding and activation
0.0 1.0 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 1.7 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.4 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.1 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.0 0.2 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.0 0.6 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 2.5 REACTOME LATE PHASE OF HIV LIFE CYCLE Genes involved in Late Phase of HIV Life Cycle
0.0 1.1 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.2 REACTOME ER PHAGOSOME PATHWAY Genes involved in ER-Phagosome pathway
0.0 2.3 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.8 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.2 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.2 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.6 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.4 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism