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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for barhl2

Z-value: 0.39

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Transcription factors associated with barhl2

Gene Symbol Gene ID Gene Info
barhl2
ENSDARG00000104361 BarH-like homeobox 2
barhl2
ENSDARG00000114681 BarH-like homeobox 2
barhl2
ENSDARG00000115723 BarH-like homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
barhl2dr11_v1_chr6_+_24817852_24817852-0.832.2e-05Click!

Activity profile of barhl2 motif

Sorted Z-values of barhl2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr2_-_17115256 1.67 ENSDART00000190488
pif1
PIF1 5'-to-3' DNA helicase homolog (S. cerevisiae)
chr6_-_8362419 1.59 ENSDART00000142752
ENSDART00000135810
acp5a
acid phosphatase 5a, tartrate resistant
chr21_+_25777425 1.28 ENSDART00000021620
cldnd
claudin d
chr1_-_33645967 1.19 ENSDART00000192758
cldng
claudin g
chr8_+_45334255 0.98 ENSDART00000126848
ENSDART00000134161
ENSDART00000142322
ENSDART00000145011
ENSDART00000183560
pabpc1l
poly(A) binding protein, cytoplasmic 1-like
chr21_-_19919020 0.89 ENSDART00000147396
ppp1r3b
protein phosphatase 1, regulatory subunit 3B
chr7_+_28724919 0.88 ENSDART00000011324
ccdc102a
coiled-coil domain containing 102A
chr5_+_29794058 0.87 ENSDART00000045410
thy1
Thy-1 cell surface antigen
chr11_-_6452444 0.85 ENSDART00000137879
ENSDART00000134957
ENSDART00000004483
larp6b
La ribonucleoprotein domain family, member 6b
chr24_-_10006158 0.85 ENSDART00000106244
zgc:171750
zgc:171750
chr3_+_43102010 0.80 ENSDART00000162096
micall2a
mical-like 2a
chr19_-_874888 0.77 ENSDART00000007206
eomesa
eomesodermin homolog a
chr1_-_55248496 0.71 ENSDART00000098615
nanos3
nanos homolog 3
chr6_+_21001264 0.71 ENSDART00000044519
ENSDART00000151278
cx44.2
connexin 44.2
chr17_+_16046314 0.70 ENSDART00000154554
ENSDART00000154338
ENSDART00000155336
si:ch73-204p21.2
si:ch73-204p21.2
chr20_-_49889111 0.69 ENSDART00000058858
kif13bb
kinesin family member 13Bb
chr16_+_47207691 0.68 ENSDART00000062507
ica1
islet cell autoantigen 1
chr12_-_11349899 0.68 ENSDART00000079645
zgc:174164
zgc:174164
chr17_+_16046132 0.68 ENSDART00000155005
si:ch73-204p21.2
si:ch73-204p21.2
chr17_+_43867889 0.68 ENSDART00000132673
ENSDART00000167214
zgc:66313
zgc:66313
chr9_-_35633827 0.68 ENSDART00000077745
zp2l1
zona pellucida glycoprotein 2, like 1
chr4_-_4259079 0.68 ENSDART00000135352
ENSDART00000026559
cd9b
CD9 molecule b
chr11_-_44801968 0.68 ENSDART00000161846
map1lc3c
microtubule-associated protein 1 light chain 3 gamma
chr20_+_27087539 0.67 ENSDART00000062094
tmem251
transmembrane protein 251
chr7_-_26270014 0.67 ENSDART00000079347
serpine1
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
chr5_-_29512538 0.67 ENSDART00000098364
ehmt1a
euchromatic histone-lysine N-methyltransferase 1a
chr17_+_21887823 0.66 ENSDART00000131929
ENSDART00000165192
plekha1a
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1a
chr22_-_22147375 0.65 ENSDART00000149304
cdc34a
cell division cycle 34 homolog (S. cerevisiae) a
chr7_+_34487833 0.64 ENSDART00000173854
cln6a
CLN6, transmembrane ER protein a
chr5_-_72390259 0.62 ENSDART00000172302
wbp1
WW domain binding protein 1
chr3_+_43373867 0.62 ENSDART00000159455
ENSDART00000172425
zfand2a
zinc finger, AN1-type domain 2A
chr9_+_500052 0.62 ENSDART00000166707
CU984600.1

chr15_+_22394074 0.62 ENSDART00000109931
oafa
OAF homolog a (Drosophila)
chr1_+_513986 0.60 ENSDART00000109083
ENSDART00000081945
txnl4b
thioredoxin-like 4B
chr11_+_11303458 0.60 ENSDART00000162486
ENSDART00000160703
si:dkey-23f9.4
si:dkey-23f9.4
chr11_+_18130300 0.59 ENSDART00000169146
zgc:175135
zgc:175135
chr17_-_30635298 0.58 ENSDART00000155478
sh3yl1
SH3 and SYLF domain containing 1
chr3_-_54607166 0.58 ENSDART00000021977
dnmt1
DNA (cytosine-5-)-methyltransferase 1
chr6_+_19948043 0.57 ENSDART00000182636
pik3r5
phosphoinositide-3-kinase, regulatory subunit 5
chr3_-_40232615 0.57 ENSDART00000155969
flii
flightless I actin binding protein
chr10_+_15024772 0.56 ENSDART00000135667
si:dkey-88l16.5
si:dkey-88l16.5
chr14_+_24845941 0.56 ENSDART00000187513
arhgef37
Rho guanine nucleotide exchange factor (GEF) 37
chr17_+_25849332 0.56 ENSDART00000191994
acss1
acyl-CoA synthetase short chain family member 1
chr5_+_6670945 0.56 ENSDART00000185686
pxna
paxillin a
chr22_-_20695237 0.55 ENSDART00000112722
org
oogenesis-related gene
chr19_-_25119443 0.55 ENSDART00000148953
ptp4a3
protein tyrosine phosphatase type IVA, member 3
chr19_-_25149034 0.55 ENSDART00000148432
ENSDART00000175266
ptp4a3
protein tyrosine phosphatase type IVA, member 3
chr20_+_14789305 0.55 ENSDART00000002463
tmed5
transmembrane p24 trafficking protein 5
chr22_-_14272699 0.53 ENSDART00000190121
si:ch211-246m6.5
si:ch211-246m6.5
chr1_+_2301961 0.52 ENSDART00000108919
ENSDART00000143361
ENSDART00000142944
farp1
FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
chr4_-_20081621 0.51 ENSDART00000024647
dennd6b
DENN/MADD domain containing 6B
chr15_+_24795473 0.51 ENSDART00000139689
ENSDART00000141033
ENSDART00000100746
ENSDART00000135677
gosr1
golgi SNAP receptor complex member 1
chr23_+_2666944 0.51 ENSDART00000192861
CABZ01057928.1

chr12_+_35203091 0.51 ENSDART00000153022
ndst2b
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2b
chr17_+_16429826 0.50 ENSDART00000136078
efcab11
EF-hand calcium binding domain 11
chr9_-_6991650 0.50 ENSDART00000081718
slc9a2
solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
chr18_+_8917766 0.50 ENSDART00000145226
si:ch211-233h19.2
si:ch211-233h19.2
chr11_+_18157260 0.50 ENSDART00000144659
zgc:173545
zgc:173545
chr17_-_14774117 0.50 ENSDART00000080401
si:ch211-266o15.1
si:ch211-266o15.1
chr11_-_35171768 0.50 ENSDART00000192896
traip
TRAF-interacting protein
chr12_+_14149686 0.48 ENSDART00000123741
kbtbd2
kelch repeat and BTB (POZ) domain containing 2
chr14_+_8940326 0.48 ENSDART00000159920
rps6kal
ribosomal protein S6 kinase a, like
chr3_+_18807006 0.47 ENSDART00000180091
tnpo2
transportin 2 (importin 3, karyopherin beta 2b)
chr1_+_21937201 0.47 ENSDART00000087729
kdm4c
lysine (K)-specific demethylase 4C
chr24_+_12835935 0.47 ENSDART00000114762
nanog
nanog homeobox
chr24_-_36238054 0.47 ENSDART00000155725
tmem241
transmembrane protein 241
chr21_+_34119759 0.47 ENSDART00000024750
ENSDART00000128242
hmgb3b
high mobility group box 3b
chr7_+_24528430 0.47 ENSDART00000133022
si:dkeyp-75h12.2
si:dkeyp-75h12.2
chr1_-_18811517 0.46 ENSDART00000142026
si:dkey-167i21.2
si:dkey-167i21.2
chr11_+_45286911 0.46 ENSDART00000181763
pycr1b
pyrroline-5-carboxylate reductase 1b
chr17_-_6613458 0.46 ENSDART00000175024
si:ch211-189e2.3
si:ch211-189e2.3
chr23_+_2917392 0.46 ENSDART00000150019
DHX35
zgc:158828
chr5_-_54554583 0.46 ENSDART00000158865
ENSDART00000158069
ssna1
Sjogren syndrome nuclear autoantigen 1
chr8_-_19467011 0.46 ENSDART00000162010
zgc:92140
zgc:92140
chr10_-_13343831 0.45 ENSDART00000135941
il11ra
interleukin 11 receptor, alpha
chr15_+_11644866 0.45 ENSDART00000188716
slc1a5
solute carrier family 1 (neutral amino acid transporter), member 5
chr15_-_30857350 0.44 ENSDART00000138988
akap1b
A kinase (PRKA) anchor protein 1b
chr5_-_42180205 0.44 ENSDART00000145247
fam222ba
family with sequence similarity 222, member Ba
chr7_+_38809241 0.43 ENSDART00000190979
harbi1
harbinger transposase derived 1
chr16_-_7793457 0.43 ENSDART00000113483
trim71
tripartite motif containing 71, E3 ubiquitin protein ligase
chr6_-_39631164 0.43 ENSDART00000104042
ENSDART00000136076
atf7b
activating transcription factor 7b
chr23_+_38171186 0.43 ENSDART00000148188
zgc:112994
zgc:112994
chr9_-_32300783 0.43 ENSDART00000078596
hspd1
heat shock 60 protein 1
chr17_+_1544903 0.42 ENSDART00000156244
ENSDART00000112183
cep170b
centrosomal protein 170B
chr5_-_69620722 0.42 ENSDART00000097248
aldh2.2
aldehyde dehydrogenase 2 family (mitochondrial), tandem duplicate 2
chr14_+_21820034 0.42 ENSDART00000122739
ctbp1
C-terminal binding protein 1
chr22_-_10541372 0.42 ENSDART00000179708
si:dkey-42i9.4
si:dkey-42i9.4
chr24_-_2450597 0.41 ENSDART00000188080
ENSDART00000093331
rreb1a
ras responsive element binding protein 1a
chr1_-_53407448 0.41 ENSDART00000160033
ENSDART00000172322
elmod2
ELMO/CED-12 domain containing 2
chr20_-_23426339 0.41 ENSDART00000004625
zar1
zygote arrest 1
chr22_+_16293071 0.41 ENSDART00000170960
dbt
dihydrolipoamide branched chain transacylase E2
chr2_-_32387441 0.41 ENSDART00000148202
ubtfl
upstream binding transcription factor, like
chr3_-_26244256 0.41 ENSDART00000103741
ppp4ca
protein phosphatase 4, catalytic subunit a
chr15_-_34408777 0.40 ENSDART00000139934
agmo
alkylglycerol monooxygenase
chr24_-_40901410 0.40 ENSDART00000170688
wdr48a
WD repeat domain 48a
chr16_+_38940758 0.40 ENSDART00000102482
ENSDART00000136215
eny2
enhancer of yellow 2 homolog (Drosophila)
chr24_-_25166720 0.40 ENSDART00000141601
phldb2b
pleckstrin homology-like domain, family B, member 2b
chr10_-_31805923 0.40 ENSDART00000077785
vps26bl
vacuolar protein sorting 26 homolog B, like
chr16_+_40340222 0.40 ENSDART00000190631
mettl6
methyltransferase like 6
chr5_-_54395488 0.40 ENSDART00000160781
zmynd19
zinc finger, MYND-type containing 19
chr17_+_46387086 0.39 ENSDART00000157079
si:dkey-206p8.1
si:dkey-206p8.1
chr13_-_31687925 0.39 ENSDART00000085989
trmt5
TRM5 tRNA methyltransferase 5 homolog (S. cerevisiae)
chr15_-_6966221 0.39 ENSDART00000165487
ENSDART00000027657
mrps22
mitochondrial ribosomal protein S22
chr2_-_57076687 0.39 ENSDART00000161523
slc25a42
solute carrier family 25, member 42
chr22_+_14117078 0.39 ENSDART00000013575
bzw1a
basic leucine zipper and W2 domains 1a
chr3_+_26244353 0.38 ENSDART00000103733
atad5a
ATPase family, AAA domain containing 5a
chr9_-_32300611 0.38 ENSDART00000127938
hspd1
heat shock 60 protein 1
chr23_-_36303216 0.38 ENSDART00000188720
cbx5
chromobox homolog 5 (HP1 alpha homolog, Drosophila)
chr15_-_25269028 0.38 ENSDART00000078230
ENSDART00000193872
mettl16
methyltransferase like 16
chr24_-_34680956 0.37 ENSDART00000171009
ctnna1
catenin (cadherin-associated protein), alpha 1
chr10_-_15854743 0.37 ENSDART00000092343
tjp2a
tight junction protein 2a (zona occludens 2)
chr19_+_29808471 0.37 ENSDART00000186428
hdac1
histone deacetylase 1
chr7_-_64971839 0.37 ENSDART00000164682
sinhcafl
SIN3-HDAC complex associated factor, like
chr9_-_14273652 0.37 ENSDART00000135458
abcb6b
ATP-binding cassette, sub-family B (MDR/TAP), member 6b
chr20_-_48700370 0.37 ENSDART00000185195
ENSDART00000184898
pax1b
paired box 1b
chr11_+_45287541 0.37 ENSDART00000165321
ENSDART00000173116
pycr1b
pyrroline-5-carboxylate reductase 1b
chr16_+_54209504 0.36 ENSDART00000020033
xrcc1
X-ray repair complementing defective repair in Chinese hamster cells 1
chr18_+_3579829 0.36 ENSDART00000158763
ENSDART00000182850
ENSDART00000162754
ENSDART00000178789
ENSDART00000172656
lrch3
leucine-rich repeats and calponin homology (CH) domain containing 3
chr7_+_61764040 0.36 ENSDART00000056745
acox3
acyl-CoA oxidase 3, pristanoyl
chr23_+_32029304 0.36 ENSDART00000185217
tpx2
TPX2, microtubule-associated, homolog (Xenopus laevis)
chr2_-_55779927 0.36 ENSDART00000168579
CABZ01066725.1

chr17_+_50701748 0.35 ENSDART00000191938
ENSDART00000183220
ENSDART00000049464
fermt2
fermitin family member 2
chr9_-_30385059 0.35 ENSDART00000060134
piga
phosphatidylinositol glycan anchor biosynthesis, class A
chr19_+_40069524 0.34 ENSDART00000151365
ENSDART00000140926
zmym4
zinc finger, MYM-type 4
chr16_+_40340523 0.34 ENSDART00000102571
mettl6
methyltransferase like 6
chr7_-_40959867 0.33 ENSDART00000174009
rbm33a
RNA binding motif protein 33a
chr5_+_29652513 0.33 ENSDART00000035400
tsc1a
TSC complex subunit 1a
chr11_+_19370717 0.33 ENSDART00000165906
prickle2b
prickle homolog 2b
chr22_+_34701848 0.33 ENSDART00000082066
atpv0e2
ATPase H+ transporting V0 subunit e2
chr9_+_29431763 0.33 ENSDART00000186095
ENSDART00000182640
uggt2
UDP-glucose glycoprotein glucosyltransferase 2
chr14_+_50937757 0.32 ENSDART00000163865
rnf44
ring finger protein 44
chr12_+_33395748 0.32 ENSDART00000129458
fasn
fatty acid synthase
chr3_+_22035863 0.32 ENSDART00000177169
cdc27
cell division cycle 27
chr2_+_6253246 0.32 ENSDART00000058256
ENSDART00000076700
zp3b
zona pellucida glycoprotein 3b
chr10_-_14929630 0.31 ENSDART00000121892
ENSDART00000044756
ENSDART00000128579
ENSDART00000147653
smad2
SMAD family member 2
chr14_+_26247319 0.31 ENSDART00000192793
CCDC69
coiled-coil domain containing 69
chr20_+_18703454 0.31 ENSDART00000152342
eif5
eukaryotic translation initiation factor 5
chr15_-_26931541 0.31 ENSDART00000027563
ccdc9
coiled-coil domain containing 9
chr11_+_19080400 0.31 ENSDART00000044423
magi1b
membrane associated guanylate kinase, WW and PDZ domain containing 1b
chr20_-_34801181 0.31 ENSDART00000048375
ENSDART00000132426
stmn4
stathmin-like 4
chr5_-_35252761 0.31 ENSDART00000051278
tnpo1
transportin 1
chr24_+_39227519 0.30 ENSDART00000184611
ENSDART00000193494
ENSDART00000190728
ENSDART00000168705
MPRIP
si:ch73-103b11.2
chr19_-_34873566 0.30 ENSDART00000016057
ctnnal1
catenin (cadherin-associated protein), alpha-like 1
chr19_+_15443540 0.30 ENSDART00000193355
lin28a
lin-28 homolog A (C. elegans)
chr14_-_46113321 0.30 ENSDART00000169040
ENSDART00000161475
ENSDART00000124925
si:ch211-235e9.8
si:ch211-235e9.8
chr5_+_53580846 0.30 ENSDART00000184967
ENSDART00000161751
taf6
TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr13_-_533243 0.30 ENSDART00000038315
nvl
nuclear VCP-like
chr19_+_20793237 0.30 ENSDART00000014774
txnl4a
thioredoxin-like 4A
chr13_-_4018888 0.30 ENSDART00000058238
tjap1
tight junction associated protein 1 (peripheral)
chr6_-_51771634 0.30 ENSDART00000073847
blcap
bladder cancer associated protein
chr7_-_51368681 0.30 ENSDART00000146385
arhgap36
Rho GTPase activating protein 36
chr23_+_24973773 0.30 ENSDART00000047020
casp9
caspase 9, apoptosis-related cysteine peptidase
chr25_-_32869794 0.29 ENSDART00000162784
tmem266
transmembrane protein 266
chr16_-_35427060 0.29 ENSDART00000172294
ctps1b
CTP synthase 1b
chr8_-_38201415 0.29 ENSDART00000155189
pdlim2
PDZ and LIM domain 2 (mystique)
chr23_-_24247672 0.29 ENSDART00000141552
zbtb17
zinc finger and BTB domain containing 17
chr6_-_10037207 0.29 ENSDART00000179701
nudt15
nudix (nucleoside diphosphate linked moiety X)-type motif 15
chr11_+_25693395 0.29 ENSDART00000110224
mon1bb
MON1 secretory trafficking family member Bb
chr15_+_24676905 0.29 ENSDART00000078014
ENSDART00000143137
poldip2
polymerase (DNA-directed), delta interacting protein 2
chr4_-_20108833 0.29 ENSDART00000100867
fam3c
family with sequence similarity 3, member C
chr19_-_19871211 0.29 ENSDART00000170980
evx1
even-skipped homeobox 1
chr15_+_1534644 0.29 ENSDART00000130413
smc4
structural maintenance of chromosomes 4
chr11_+_1522136 0.29 ENSDART00000002318
srsf6b
serine/arginine-rich splicing factor 6b
chr18_-_34549721 0.28 ENSDART00000137101
ENSDART00000021880
ssr3
signal sequence receptor, gamma
chr18_-_18942098 0.28 ENSDART00000100458
si:dkey-73n10.1
si:dkey-73n10.1
chr10_-_44560165 0.27 ENSDART00000181217
ENSDART00000076084
npm2b
nucleophosmin/nucleoplasmin, 2b
chr20_+_34671386 0.27 ENSDART00000152836
ENSDART00000138226
elp3
elongator acetyltransferase complex subunit 3
chr22_+_786556 0.27 ENSDART00000125347
cry1bb
cryptochrome circadian clock 1bb
chr10_+_17371356 0.27 ENSDART00000122663
sppl3
signal peptide peptidase 3
chr16_-_25680666 0.27 ENSDART00000132693
ENSDART00000140539
ENSDART00000015302
tomm40
translocase of outer mitochondrial membrane 40 homolog (yeast)
chr8_-_50888806 0.27 ENSDART00000053750
acsl2
acyl-CoA synthetase long chain family member 2
chr19_-_8768564 0.27 ENSDART00000170416
si:ch73-350k19.1
si:ch73-350k19.1
chr22_+_883678 0.27 ENSDART00000140588
stk38b
serine/threonine kinase 38b
chr6_-_42336987 0.26 ENSDART00000128777
ENSDART00000075601
fancd2
Fanconi anemia, complementation group D2
chr7_+_24153070 0.26 ENSDART00000076735
lrp10
low density lipoprotein receptor-related protein 10
chr11_-_25461336 0.26 ENSDART00000014945
hcfc1a
host cell factor C1a
chr21_+_43702016 0.26 ENSDART00000017176
dkc1
dyskeratosis congenita 1, dyskerin
chr23_-_15916316 0.26 ENSDART00000134096
ENSDART00000042469
ENSDART00000146605
mrgbp
MRG/MORF4L binding protein
chr16_-_13680692 0.26 ENSDART00000047452
ube2s
ubiquitin-conjugating enzyme E2S
chr19_+_29808699 0.25 ENSDART00000051799
ENSDART00000164205
hdac1
histone deacetylase 1
chr2_-_54039293 0.25 ENSDART00000166013
abhd8a
abhydrolase domain containing 8a
chr22_+_34784075 0.25 ENSDART00000167538
lcor
ligand dependent nuclear receptor corepressor
chr6_-_3982783 0.25 ENSDART00000171944
slc25a12
solute carrier family 25 (aspartate/glutamate carrier), member 12
chr6_+_40922572 0.24 ENSDART00000133599
ENSDART00000002728
ENSDART00000145153
eif4enif1
eukaryotic translation initiation factor 4E nuclear import factor 1
chr13_+_6188759 0.24 ENSDART00000161062
ppm1g
protein phosphatase, Mg2+/Mn2+ dependent, 1G
chr3_+_32791786 0.24 ENSDART00000180174
tbc1d10b
TBC1 domain family, member 10b
chr20_+_18703108 0.24 ENSDART00000181188
eif5
eukaryotic translation initiation factor 5
chr13_+_1100197 0.24 ENSDART00000139560
ppp3r1a
protein phosphatase 3, regulatory subunit B, alpha a
chr20_+_18703695 0.24 ENSDART00000137766
eif5
eukaryotic translation initiation factor 5
chr16_-_24642814 0.24 ENSDART00000153987
ENSDART00000154319
fxyd6l
FXYD domain containing ion transport regulator 6 like
chr20_-_54924593 0.24 ENSDART00000151522
si:dkey-15f23.1
si:dkey-15f23.1
chr8_-_10949847 0.24 ENSDART00000123209
pqlc2
PQ loop repeat containing 2
chr2_+_16652238 0.24 ENSDART00000091351
gk5
glycerol kinase 5 (putative)
chr10_-_33297864 0.23 ENSDART00000163360
PRDM15
PR/SET domain 15
chr21_+_27302752 0.23 ENSDART00000012855
sart1
SART1, U4/U6.U5 tri-snRNP-associated protein 1
chr25_+_17590095 0.23 ENSDART00000009767
vac14
vac14 homolog (S. cerevisiae)
chr2_-_38206034 0.23 ENSDART00000144518
ENSDART00000137395
acin1a
apoptotic chromatin condensation inducer 1a
chr10_+_43039947 0.23 ENSDART00000193434
atg10
ATG10 autophagy related 10 homolog (S. cerevisiae)
chr3_-_32873641 0.23 ENSDART00000075277
zgc:113090
zgc:113090
chr11_-_40457325 0.22 ENSDART00000128442
tnfrsf1b
tumor necrosis factor receptor superfamily, member 1B

Network of associatons between targets according to the STRING database.

First level regulatory network of barhl2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.5 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.3 0.9 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.3 0.8 GO:0055109 invagination involved in gastrulation with mouth forming second(GO:0055109) morphogenesis of an epithelial fold(GO:0060571)
0.2 0.8 GO:0045041 positive regulation of interleukin-6 production(GO:0032755) protein import into mitochondrial intermembrane space(GO:0045041)
0.2 0.7 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.1 1.7 GO:0000002 mitochondrial genome maintenance(GO:0000002)
0.1 1.6 GO:0045453 bone resorption(GO:0045453)
0.1 0.4 GO:1903003 positive regulation of protein deubiquitination(GO:1903003)
0.1 0.4 GO:0090004 positive regulation of Golgi to plasma membrane protein transport(GO:0042998) positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
0.1 0.5 GO:0032776 DNA methylation on cytosine(GO:0032776)
0.1 0.5 GO:0048209 regulation of vesicle targeting, to, from or within Golgi(GO:0048209)
0.1 0.3 GO:0051973 positive regulation of telomerase activity(GO:0051973)
0.1 0.4 GO:0070900 mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864)
0.1 0.5 GO:0006978 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978) DNA damage response, signal transduction resulting in transcription(GO:0042772)
0.1 0.6 GO:0006083 acetate metabolic process(GO:0006083) acetyl-CoA biosynthetic process from acetate(GO:0019427)
0.1 0.8 GO:0006561 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.1 0.3 GO:0002926 tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridine biosynthesis.(GO:0002926)
0.1 0.4 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.1 0.6 GO:0033687 osteoblast proliferation(GO:0033687)
0.1 0.4 GO:0010586 miRNA metabolic process(GO:0010586)
0.1 0.3 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.1 0.3 GO:0010755 regulation of plasminogen activation(GO:0010755)
0.1 0.4 GO:0046485 ether lipid metabolic process(GO:0046485)
0.1 0.3 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.1 0.4 GO:0000012 single strand break repair(GO:0000012)
0.1 0.3 GO:0070987 error-free translesion synthesis(GO:0070987)
0.1 0.7 GO:0072386 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.1 0.2 GO:0046099 guanine salvage(GO:0006178) GMP salvage(GO:0032263) guanine biosynthetic process(GO:0046099)
0.1 0.2 GO:0006041 glucosamine metabolic process(GO:0006041) glucosamine catabolic process(GO:0006043)
0.1 0.2 GO:0071042 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476) nuclear polyadenylation-dependent mRNA catabolic process(GO:0071042) polyadenylation-dependent mRNA catabolic process(GO:0071047)
0.1 0.5 GO:0006971 hypotonic response(GO:0006971) hypotonic salinity response(GO:0042539)
0.1 0.3 GO:0097272 ammonia homeostasis(GO:0097272)
0.1 0.4 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.1 0.3 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.1 0.3 GO:1990918 double-strand break repair involved in meiotic recombination(GO:1990918)
0.1 0.5 GO:0006465 signal peptide processing(GO:0006465)
0.1 0.2 GO:1903504 regulation of spindle checkpoint(GO:0090231) regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.1 0.4 GO:0016578 histone deubiquitination(GO:0016578)
0.0 0.3 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.0 0.9 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.0 0.5 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.2 GO:0042780 tRNA 3'-end processing(GO:0042780)
0.0 0.2 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.0 0.1 GO:0031335 regulation of sulfur amino acid metabolic process(GO:0031335) regulation of homocysteine metabolic process(GO:0050666)
0.0 0.2 GO:0019563 glycerol catabolic process(GO:0019563)
0.0 0.4 GO:1901678 heme transport(GO:0015886) iron coordination entity transport(GO:1901678)
0.0 0.6 GO:0061055 myotome development(GO:0061055)
0.0 0.3 GO:0006203 dGTP catabolic process(GO:0006203) purine nucleoside triphosphate catabolic process(GO:0009146) purine deoxyribonucleoside triphosphate catabolic process(GO:0009217) dGTP metabolic process(GO:0046070)
0.0 0.7 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.2 GO:0003173 ventriculo bulbo valve development(GO:0003173)
0.0 0.2 GO:0060368 regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060368)
0.0 0.1 GO:0036306 embryonic heart tube elongation(GO:0036306)
0.0 0.7 GO:0050796 regulation of insulin secretion(GO:0050796)
0.0 0.2 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.1 GO:2000008 regulation of protein localization to cell surface(GO:2000008) negative regulation of protein localization to cell surface(GO:2000009)
0.0 0.1 GO:0016267 O-glycan processing, core 1(GO:0016267)
0.0 0.3 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.5 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.3 GO:1902101 positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.0 0.3 GO:0060573 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.0 0.4 GO:0060236 regulation of mitotic spindle organization(GO:0060236)
0.0 0.2 GO:0048069 eye pigmentation(GO:0048069)
0.0 0.2 GO:0015810 acidic amino acid transport(GO:0015800) aspartate transport(GO:0015810) L-glutamate transport(GO:0015813) malate-aspartate shuttle(GO:0043490)
0.0 0.3 GO:0045740 positive regulation of DNA replication(GO:0045740)
0.0 0.4 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.0 0.1 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.0 0.3 GO:0046627 negative regulation of insulin receptor signaling pathway(GO:0046627) negative regulation of cellular response to insulin stimulus(GO:1900077)
0.0 0.2 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.0 0.3 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.0 0.3 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.0 0.1 GO:0040031 snRNA modification(GO:0040031) positive regulation of protein localization to nucleus(GO:1900182) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871)
0.0 0.1 GO:0090646 mitochondrial tRNA processing(GO:0090646)
0.0 0.4 GO:0009081 branched-chain amino acid metabolic process(GO:0009081)
0.0 0.8 GO:0097205 renal filtration(GO:0097205)
0.0 0.2 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.0 0.1 GO:0061635 regulation of protein complex stability(GO:0061635)
0.0 0.1 GO:0090177 establishment of planar polarity of embryonic epithelium(GO:0042249) establishment of planar polarity involved in neural tube closure(GO:0090177) regulation of establishment of planar polarity involved in neural tube closure(GO:0090178) planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.0 0.0 GO:0070169 positive regulation of bone mineralization(GO:0030501) positive regulation of ossification(GO:0045778) positive regulation of biomineral tissue development(GO:0070169)
0.0 0.1 GO:0044805 late nucleophagy(GO:0044805)
0.0 0.3 GO:0060046 binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.0 0.6 GO:0051014 actin filament severing(GO:0051014)
0.0 0.3 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0 0.1 GO:0019418 sulfide oxidation(GO:0019418) sulfide oxidation, using sulfide:quinone oxidoreductase(GO:0070221)
0.0 0.3 GO:0008089 anterograde axonal transport(GO:0008089)
0.0 0.2 GO:0002551 mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.0 0.6 GO:0007040 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.0 0.1 GO:0031571 mitotic G1 DNA damage checkpoint(GO:0031571)
0.0 0.1 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.3 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 0.4 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.0 0.6 GO:0051904 melanosome transport(GO:0032402) pigment granule transport(GO:0051904)
0.0 0.2 GO:0007004 RNA-dependent DNA biosynthetic process(GO:0006278) telomere maintenance via telomerase(GO:0007004)
0.0 0.1 GO:0046247 carotene metabolic process(GO:0016119) carotene catabolic process(GO:0016121) terpene metabolic process(GO:0042214) terpene catabolic process(GO:0046247)
0.0 0.9 GO:0034968 histone lysine methylation(GO:0034968)
0.0 0.2 GO:1901534 positive regulation of hematopoietic progenitor cell differentiation(GO:1901534)
0.0 0.4 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.0 0.1 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.0 0.2 GO:0035493 SNARE complex assembly(GO:0035493)
0.0 0.2 GO:0042026 protein refolding(GO:0042026)
0.0 0.6 GO:0007338 single fertilization(GO:0007338)
0.0 0.1 GO:1905066 regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066)
0.0 0.1 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.0 0.1 GO:0021627 olfactory nerve development(GO:0021553) olfactory nerve morphogenesis(GO:0021627) olfactory nerve formation(GO:0021628)
0.0 0.1 GO:0016322 neuron remodeling(GO:0016322)
0.0 0.2 GO:0051382 kinetochore assembly(GO:0051382)
0.0 0.5 GO:0060968 regulation of gene silencing(GO:0060968)
0.0 0.1 GO:0016926 protein desumoylation(GO:0016926)
0.0 0.0 GO:0015919 peroxisomal membrane transport(GO:0015919) protein import into peroxisome membrane(GO:0045046)
0.0 0.1 GO:0097341 inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341)
0.0 0.3 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0 0.1 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.0 0.2 GO:0006506 GPI anchor biosynthetic process(GO:0006506)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0005797 Golgi medial cisterna(GO:0005797)
0.1 0.4 GO:0005880 nuclear microtubule(GO:0005880)
0.1 0.4 GO:0070390 transcription export complex 2(GO:0070390)
0.1 0.3 GO:0046695 SLIK (SAGA-like) complex(GO:0046695)
0.1 0.3 GO:0097268 cytoophidium(GO:0097268)
0.1 0.3 GO:0098553 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.1 0.3 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.1 1.1 GO:0005682 U5 snRNP(GO:0005682)
0.1 0.3 GO:0072588 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.1 1.0 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 0.3 GO:0031258 lamellipodium membrane(GO:0031258)
0.1 0.3 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.2 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.4 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.6 GO:0097651 phosphatidylinositol 3-kinase complex, class IB(GO:0005944) phosphatidylinositol 3-kinase complex, class I(GO:0097651)
0.0 0.5 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.2 GO:0070209 ASTRA complex(GO:0070209)
0.0 0.4 GO:0030904 retromer complex(GO:0030904)
0.0 0.1 GO:0033065 Rad51C-XRCC3 complex(GO:0033065)
0.0 1.5 GO:0005657 replication fork(GO:0005657)
0.0 0.7 GO:0030667 secretory granule membrane(GO:0030667)
0.0 0.2 GO:0035032 extrinsic component of vacuolar membrane(GO:0000306) phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0 3.5 GO:0005923 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 0.7 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.3 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.3 GO:0000124 SAGA complex(GO:0000124)
0.0 0.2 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.0 0.9 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.2 GO:0000798 nuclear cohesin complex(GO:0000798) mitotic cohesin complex(GO:0030892) nuclear mitotic cohesin complex(GO:0034990) nuclear meiotic cohesin complex(GO:0034991)
0.0 0.1 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.0 0.4 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.1 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 0.3 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 0.4 GO:0030057 desmosome(GO:0030057)
0.0 0.7 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.5 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.4 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.4 GO:0045180 basal cortex(GO:0045180)
0.0 0.2 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 0.3 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.3 GO:0035267 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 0.6 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.2 GO:0046540 U4/U6 x U5 tri-snRNP complex(GO:0046540)
0.0 0.1 GO:0035517 PR-DUB complex(GO:0035517)
0.0 0.2 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.9 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.1 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 0.1 GO:0035145 exon-exon junction complex(GO:0035145)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.7 GO:0043139 5'-3' DNA helicase activity(GO:0043139)
0.2 1.6 GO:0003993 acid phosphatase activity(GO:0003993)
0.2 1.0 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.2 0.8 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.1 0.4 GO:0071077 coenzyme A transmembrane transporter activity(GO:0015228) adenosine 3',5'-bisphosphate transmembrane transporter activity(GO:0071077) AMP transmembrane transporter activity(GO:0080122)
0.1 0.4 GO:0001734 mRNA (N6-adenosine)-methyltransferase activity(GO:0001734)
0.1 0.4 GO:0071253 connexin binding(GO:0071253)
0.1 0.5 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.1 0.6 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.1 0.3 GO:0004087 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087)
0.1 0.2 GO:0019777 Atg12 transferase activity(GO:0019777)
0.1 0.3 GO:0003883 CTP synthase activity(GO:0003883)
0.1 0.4 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.1 1.0 GO:0008266 poly(U) RNA binding(GO:0008266)
0.1 1.0 GO:2001069 glycogen binding(GO:2001069)
0.1 0.3 GO:0003980 UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980)
0.1 0.3 GO:0070182 DNA polymerase binding(GO:0070182)
0.1 0.5 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.1 0.2 GO:0004422 hypoxanthine phosphoribosyltransferase activity(GO:0004422)
0.1 0.2 GO:0004342 glucosamine-6-phosphate deaminase activity(GO:0004342)
0.0 0.3 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.4 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.8 GO:0061608 nuclear import signal receptor activity(GO:0061608)
0.0 0.5 GO:0005451 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.0 0.4 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.0 0.6 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.6 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.8 GO:0002039 p53 binding(GO:0002039)
0.0 0.4 GO:0035198 miRNA binding(GO:0035198)
0.0 0.2 GO:0004419 hydroxymethylglutaryl-CoA lyase activity(GO:0004419)
0.0 0.6 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.5 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.0 0.2 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.4 GO:0005504 fatty acid binding(GO:0005504)
0.0 0.2 GO:0015616 DNA translocase activity(GO:0015616)
0.0 0.3 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.5 GO:0031729 CCR1 chemokine receptor binding(GO:0031726) CCR4 chemokine receptor binding(GO:0031729)
0.0 0.4 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.0 0.1 GO:0061656 SUMO conjugating enzyme activity(GO:0061656)
0.0 0.3 GO:0035804 structural constituent of egg coat(GO:0035804)
0.0 0.1 GO:0016263 glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity(GO:0016263) beta-1,3-galactosyltransferase activity(GO:0048531)
0.0 0.5 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.3 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.0 0.4 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.1 GO:0004122 cystathionine beta-synthase activity(GO:0004122)
0.0 0.4 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.4 GO:0016251 obsolete general RNA polymerase II transcription factor activity(GO:0016251)
0.0 0.7 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.1 GO:0003909 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0 1.2 GO:0005178 integrin binding(GO:0005178)
0.0 0.2 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.0 0.2 GO:0017091 AU-rich element binding(GO:0017091) mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 1.0 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.3 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0 0.1 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 0.3 GO:0008320 protein transmembrane transporter activity(GO:0008320)
0.0 0.1 GO:0070224 sulfide:quinone oxidoreductase activity(GO:0070224)
0.0 0.1 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.0 0.6 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.2 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 0.1 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.0 GO:0061650 ubiquitin-like protein conjugating enzyme activity(GO:0061650) UFM1 transferase activity(GO:0071568)
0.0 0.3 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.1 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0 0.1 GO:0003834 beta-carotene 15,15'-monooxygenase activity(GO:0003834) carotenoid dioxygenase activity(GO:0010436)
0.0 0.1 GO:0050699 WW domain binding(GO:0050699)
0.0 0.2 GO:0004724 magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
0.0 0.1 GO:0048763 ryanodine-sensitive calcium-release channel activity(GO:0005219) calcium-induced calcium release activity(GO:0048763)
0.0 0.3 GO:0051371 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.0 3.2 GO:0042802 identical protein binding(GO:0042802)
0.0 0.9 GO:0031625 ubiquitin protein ligase binding(GO:0031625)
0.0 0.1 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.0 0.5 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.5 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.1 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.1 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.0 0.6 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.1 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 0.1 GO:0072518 Rho-dependent protein serine/threonine kinase activity(GO:0072518)
0.0 0.5 GO:0000049 tRNA binding(GO:0000049)
0.0 0.1 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.0 0.1 GO:0015299 solute:proton antiporter activity(GO:0015299)
0.0 0.5 GO:0003727 single-stranded RNA binding(GO:0003727)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.7 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.8 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.6 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.3 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.7 PID ATM PATHWAY ATM pathway
0.0 1.0 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 2.0 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 0.4 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.2 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.6 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 0.4 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 0.4 PID AURORA A PATHWAY Aurora A signaling
0.0 0.3 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.7 PID AURORA B PATHWAY Aurora B signaling
0.0 0.5 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 0.6 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 0.4 PID MYC PATHWAY C-MYC pathway
0.0 0.5 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.6 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.2 PID HNF3A PATHWAY FOXA1 transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.1 1.6 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.5 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.3 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 0.5 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0 1.5 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.2 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.0 0.6 REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.0 0.3 REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.0 0.4 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.2 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.3 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.2 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.2 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 0.2 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.2 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.2 REACTOME FATTY ACYL COA BIOSYNTHESIS Genes involved in Fatty Acyl-CoA Biosynthesis
0.0 0.4 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.4 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.3 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.1 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.0 0.2 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.1 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0 0.3 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 0.1 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1