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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for cdc5l

Z-value: 0.61

Motif logo

Transcription factors associated with cdc5l

Gene Symbol Gene ID Gene Info
ENSDARG00000043797 CDC5 cell division cycle 5-like (S. pombe)

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
cdc5ldr11_v1_chr17_+_5061135_5061135-0.243.3e-01Click!

Activity profile of cdc5l motif

Sorted Z-values of cdc5l motif

Promoter Log-likelihood Transcript Gene Gene Info
chr5_+_42308955 1.56 ENSDART00000136683
Pim proto-oncogene, serine/threonine kinase, related 201
chr10_+_439692 1.12 ENSDART00000147740
zinc finger, DHHC-type containing 8a
chr16_-_29557338 1.05 ENSDART00000058888
HORMA domain containing 1
chr24_-_2959091 0.97 ENSDART00000170525
ENSDART00000162143
cell death-inducing DFFA-like effector a
chr22_+_3223489 0.96 ENSDART00000082011
lens intrinsic membrane protein 2.2
chr5_-_41494831 0.95 ENSDART00000051081
eukaryotic translation elongation factor 2, like 2
chr14_-_33360344 0.91 ENSDART00000181291
Pim proto-oncogene, serine/threonine kinase, related 117
chr2_-_38000276 0.90 ENSDART00000034790
Purkinje cell protein 4 like 1
chr25_-_19585010 0.88 ENSDART00000021340
synaptonemal complex protein 3
chr24_+_22022109 0.85 ENSDART00000133686
rhophilin associated tail protein 1-like
chr24_+_13277573 0.85 ENSDART00000137886
si:ch211-171b20.3
chr2_-_45691128 0.84 ENSDART00000125406
family with sequence similarity 102, member B, a
chr14_-_33387288 0.82 ENSDART00000171388
Pim proto-oncogene, serine/threonine kinase, related 119
chr15_+_1148074 0.81 ENSDART00000152638
ENSDART00000152466
ENSDART00000188011
myeloid leukemia factor 1
chr21_-_29990574 0.78 ENSDART00000185800
si:ch73-190f9.4
chr8_+_17933475 0.77 ENSDART00000100651
glutamate-rich 3
chr1_-_10806625 0.77 ENSDART00000139749
si:ch73-222h13.1
chr24_+_22021675 0.76 ENSDART00000081234
rhophilin associated tail protein 1-like
chr22_-_15562933 0.75 ENSDART00000141528
ankyrin repeat and MYND domain containing 1
chr3_+_62126981 0.74 ENSDART00000060527
dynein regulatory complex subunit 3
chr4_+_912563 0.73 ENSDART00000103631
ripply transcriptional repressor 2
chr19_+_34274504 0.72 ENSDART00000132046
si:ch211-9n13.3
chr16_-_35579200 0.72 ENSDART00000162172
Scm polycomb group protein homolog 1
chr24_+_39443874 0.72 ENSDART00000142998
dynein axonemal heavy chain 3
chr23_+_27352072 0.72 ENSDART00000144762
si:dkey-9p24.5
chr14_-_33407997 0.72 ENSDART00000163296
Pim proto-oncogene, serine/threonine kinase, related 118
chr5_-_29671586 0.69 ENSDART00000098336
sperm acrosome associated 9
chr24_-_26310854 0.66 ENSDART00000080113
apolipoprotein Db
chr20_+_35438300 0.66 ENSDART00000102504
ENSDART00000153249
tudor domain containing 6
chr25_-_19584735 0.66 ENSDART00000137930
synaptonemal complex protein 3
chr21_-_29477624 0.66 ENSDART00000180110

chr21_-_29940453 0.65 ENSDART00000182862

chr21_-_41870029 0.65 ENSDART00000182035
endonuclease, polyU-specific 2
chr6_+_12968101 0.64 ENSDART00000013781
minichromosome maintenance complex component 6
chr21_-_29735366 0.63 ENSDART00000181668

chr21_-_29689141 0.61 ENSDART00000100876

chr4_-_13567387 0.60 ENSDART00000132971
ENSDART00000102010
Mdm1 nuclear protein homolog (mouse)
chr17_-_52521002 0.60 ENSDART00000114931
prospero homeobox 2
chr3_+_62161184 0.60 ENSDART00000090370
ENSDART00000192665
NADPH oxidase organizer 1a
chr19_+_636886 0.59 ENSDART00000149192
telomerase reverse transcriptase
chr25_-_4192637 0.59 ENSDART00000153832
protein phosphatase 1, regulatory subunit 32
chr5_+_29671681 0.58 ENSDART00000043096
adenylate kinase 8
chr16_+_4838808 0.58 ENSDART00000179363
inhibitor of Bruton agammaglobulinemia tyrosine kinase
chr25_+_5035343 0.57 ENSDART00000011751
parvin, beta
chr14_-_33396934 0.57 ENSDART00000158606
Pim proto-oncogene, serine/threonine kinase, related 111
chr25_-_4482449 0.57 ENSDART00000056278
ENSDART00000149425
solute carrier family 25 member 22a
chr24_+_24064562 0.55 ENSDART00000144394
zgc:112408
chr23_+_45512825 0.55 ENSDART00000064846
PRELI domain containing 1b
chr4_-_56068511 0.55 ENSDART00000168345
zinc finger protein 1133
chr24_+_12945803 0.55 ENSDART00000005105
proteasome activator subunit 1
chr21_+_13577227 0.55 ENSDART00000146283
si:dkey-248f6.3
chr8_-_11546175 0.55 ENSDART00000081909
si:ch211-248e11.2
chr2_+_22531185 0.54 ENSDART00000171959
HFM1, ATP-dependent DNA helicase homolog (S. cerevisiae)
chr1_+_57269441 0.54 ENSDART00000149688
mycbp associated protein
chr1_+_50538839 0.54 ENSDART00000020412
polycystic kidney disease 2
chr21_+_20771082 0.53 ENSDART00000079732
3-oxoacid CoA transferase 1b
chr21_-_29533723 0.52 ENSDART00000193554

chr25_-_15245475 0.51 ENSDART00000142943
coiled-coil domain containing 73
chr17_+_27545183 0.51 ENSDART00000129392
PARK2 co-regulated
chr7_-_59311165 0.50 ENSDART00000171105
meiosis 1 associated protein
chr13_+_36764715 0.50 ENSDART00000111832
ENSDART00000085230
atlastin GTPase 1
chr8_-_4431971 0.49 ENSDART00000141728
ENSDART00000133519
RAD9 checkpoint clamp component B
chr17_+_25414033 0.49 ENSDART00000001691
L-threonine dehydrogenase 2
chr19_-_3127271 0.49 ENSDART00000146928
ENSDART00000134197
si:ch211-80h18.1
chr8_-_29719393 0.49 ENSDART00000077635
si:ch211-103n10.5
chr18_+_1145571 0.48 ENSDART00000135055
REC114 meiotic recombination protein
chr3_-_2593859 0.48 ENSDART00000143826
si:dkey-217f16.5
chr12_+_20641102 0.47 ENSDART00000152964
calcium binding and coiled-coil domain 2
chr17_-_36936856 0.46 ENSDART00000010274
ENSDART00000188887
dihydropyrimidinase-like 5a
chr23_-_3409140 0.46 ENSDART00000002309
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog Ba
chr24_+_26345427 0.46 ENSDART00000089756
leucine rich repeat containing 34
chr14_-_33370378 0.46 ENSDART00000180068
Pim proto-oncogene, serine/threonine kinase, related 120
chr25_-_7764083 0.46 ENSDART00000179800
ENSDART00000181858
PHD finger protein 21Ab
chr5_+_53824959 0.45 ENSDART00000169565
spermidine/spermine N1-acetyltransferase family member 2b
chr14_+_6991142 0.45 ENSDART00000157635
ENSDART00000059918
heterogeneous nuclear ribonucleoprotein H1
chr4_+_14900042 0.45 ENSDART00000018261
aldo-keto reductase family 1, member B1 (aldose reductase)
chr24_-_26399623 0.45 ENSDART00000112317
zgc:194621
chr3_-_16537441 0.45 ENSDART00000080749
ENSDART00000133824
eps8-like1
chr14_-_28432699 0.44 ENSDART00000054062
NIMA-related kinase 12
chr16_-_25085327 0.43 ENSDART00000077661
protease, serine 1
chr25_-_9013963 0.43 ENSDART00000073912
recombination activating gene 2
chr17_-_31695217 0.43 ENSDART00000104332
ENSDART00000143090
lin-52 DREAM MuvB core complex component
chr1_+_2129164 0.43 ENSDART00000074923
ENSDART00000124534
muscleblind-like splicing regulator 2
chr19_-_19339285 0.43 ENSDART00000158413
ENSDART00000170479
chondroitin sulfate proteoglycan 5b
chr4_-_11580948 0.43 ENSDART00000049066
neuroepithelial cell transforming 1
chr22_-_20309283 0.42 ENSDART00000182125
ENSDART00000048775
si:dkey-110c1.10
chr11_+_1533097 0.42 ENSDART00000066191
intraflagellar transport 52 homolog (Chlamydomonas)
chr16_-_12809873 0.42 ENSDART00000146997
ENSDART00000178291
ENSDART00000007842
isochorismatase domain containing 2
chr21_-_32301109 0.42 ENSDART00000139890
CDC-like kinase 4b
chr4_-_17642168 0.41 ENSDART00000007030
kelch-like family, member 42
chr2_+_6181383 0.41 ENSDART00000153307
si:ch73-344o19.1
chr16_-_1757521 0.41 ENSDART00000124660
activating signal cointegrator 1 complex subunit 3
chr19_-_20163197 0.40 ENSDART00000148179
ENSDART00000151646
family with sequence similarity 221, member A
chr10_+_6625785 0.40 ENSDART00000148433
si:ch211-57m13.3
chr19_+_25497541 0.40 ENSDART00000144300
collagen, type XXVIII, alpha 1a
chr18_+_21122818 0.40 ENSDART00000060015
ENSDART00000060184
choline kinase alpha
chr24_-_3426620 0.40 ENSDART00000184346
NCK adaptor protein 1b
chr20_-_1174266 0.39 ENSDART00000023304
gamma-aminobutyric acid (GABA) A receptor, rho 2b
chr18_+_36914221 0.39 ENSDART00000147656
si:ch211-238g23.1
chr1_-_44701313 0.38 ENSDART00000193926
si:dkey-28b4.8
chr10_-_44026369 0.38 ENSDART00000185456
crystallin, beta B1
chr21_+_27382893 0.38 ENSDART00000005682
actinin alpha 3a
chr17_-_26926577 0.38 ENSDART00000050202
regulator of calcineurin 3
chr7_-_52388090 0.38 ENSDART00000174104
WD repeat domain 93
chr23_-_19558556 0.38 ENSDART00000134012
dynein, axonemal, heavy chain 12
chr14_-_41285392 0.38 ENSDART00000147389
transmembrane protein 35
chr23_+_32011768 0.37 ENSDART00000053509
pleiomorphic adenoma gene X
chr6_+_46259950 0.37 ENSDART00000032326
zgc:162324
chr10_-_5844915 0.36 ENSDART00000185929
ankyrin repeat domain 55
chr1_+_12009673 0.36 ENSDART00000080100
solute carrier family 24 (sodium/potassium/calcium exchanger), member 2
chr8_-_12403077 0.36 ENSDART00000142150
PHD finger protein 19
chr1_-_51734524 0.35 ENSDART00000109640
ENSDART00000122628
JunB proto-oncogene, AP-1 transcription factor subunit a
chr10_+_31222433 0.35 ENSDART00000185080
transmembrane protein 218
chr22_-_10580194 0.35 ENSDART00000105848
si:dkey-42i9.7
chr24_+_40860320 0.35 ENSDART00000161351
golgi reassembly stacking protein 1b
chr22_-_31059670 0.34 ENSDART00000022445
cullin-associated and neddylation-dissociated 2 (putative)
chr7_-_16598212 0.34 ENSDART00000128488
E2F transcription factor 8
chr13_+_4409294 0.34 ENSDART00000146437
si:ch211-130h14.4
chr7_+_20467549 0.34 ENSDART00000173724
si:dkey-33c9.8
chr4_-_71110826 0.34 ENSDART00000167431
si:dkeyp-80d11.1
chr5_-_69425224 0.33 ENSDART00000158096

chr6_-_49063085 0.33 ENSDART00000156124
si:ch211-105j21.9
chr20_-_29787192 0.33 ENSDART00000125348
ENSDART00000048759
inhibitor of DNA binding 2b
chr24_-_38657683 0.32 ENSDART00000154843
si:ch1073-164k15.3
chr22_+_1911269 0.32 ENSDART00000164158
ENSDART00000168205
zinc finger protein 1156
chr7_-_24994722 0.32 ENSDART00000131671
REST corepressor 2
chr24_+_26345609 0.32 ENSDART00000186844
leucine rich repeat containing 34
chr17_+_6563307 0.32 ENSDART00000156454
adhesion G protein-coupled receptor F3a
chr13_-_6218248 0.32 ENSDART00000159052
si:zfos-1056e6.1
chr8_-_6918290 0.32 ENSDART00000138259
ENSDART00000142496
ankyrin repeat and SOCS box containing 6
chr11_+_16152316 0.32 ENSDART00000081054
transcriptional adaptor 3 (NGG1 homolog, yeast)-like
chr1_+_25178106 0.32 ENSDART00000054265
ENSDART00000141648
meiotic nuclear divisions 1 homolog (S. cerevisiae)
chr19_+_5604241 0.31 ENSDART00000011025
WAS/WASL interacting protein family, member 2b
chr21_+_18925318 0.31 ENSDART00000136182
si:ch211-222n4.2
chr20_+_263056 0.31 ENSDART00000132669
tubulin, epsilon 1
chr24_+_12989727 0.31 ENSDART00000126842
ENSDART00000129309
hypothetical protein FLJ11011-like (H. sapiens)
chr2_-_42958619 0.31 ENSDART00000144317
otoconin 90
chr22_+_15898221 0.31 ENSDART00000062587
Kruppel-like factor 2a
chr18_+_20838786 0.31 ENSDART00000138692
tetratricopeptide repeat domain 23
chr3_+_28831450 0.31 ENSDART00000055422
fleer
chr4_+_35553514 0.31 ENSDART00000182938

chr1_+_49651016 0.31 ENSDART00000074380
ENSDART00000101017
testis specific, 10
chr24_+_23742690 0.31 ENSDART00000130162
transcription factor 24
chr15_-_20024205 0.31 ENSDART00000161379
autism susceptibility candidate 2b
chr1_-_36151377 0.30 ENSDART00000037516
zinc finger protein 827
chr7_-_51757085 0.30 ENSDART00000167747
liver-expressed antimicrobial peptide 2
chr7_-_22956889 0.30 ENSDART00000101447
TNF superfamily member 10, like
chr23_+_37086159 0.30 ENSDART00000074407
ceramide-1-phosphate transfer protein
chr16_-_21540077 0.30 ENSDART00000078790
serine/threonine kinase 31
chr24_-_20369604 0.30 ENSDART00000143174
deleted in lung and esophageal cancer 1
chr1_-_7570181 0.30 ENSDART00000103588
myxovirus (influenza) resistance A
chr12_+_48220584 0.29 ENSDART00000164392
leucine rich repeat containing 20
chr6_-_49526510 0.29 ENSDART00000128025
ribosomal protein S26, like
chr6_+_9893554 0.29 ENSDART00000064979
Pim proto-oncogene, serine/threonine kinase, related 74
chr15_+_19293744 0.29 ENSDART00000184994
ENSDART00000123815
junctional adhesion molecule 3a
chr11_-_16395956 0.29 ENSDART00000115085
leucine-rich repeats and immunoglobulin-like domains 1
chr14_+_15622817 0.29 ENSDART00000158624
si:dkey-203a12.9
chr2_-_42960353 0.29 ENSDART00000098303
otoconin 90
chr5_+_70155935 0.29 ENSDART00000165570
regulator of G protein signaling 3a
chr4_+_686157 0.29 ENSDART00000169748
F-box protein 7
chr25_+_31267268 0.28 ENSDART00000181239
troponin I type 2a (skeletal, fast), tandem duplicate 3
chr16_-_25699554 0.28 ENSDART00000155899
ENSDART00000114495
DEAD (Asp-Glu-Ala-Asp) box helicase 61
chr7_+_25053331 0.28 ENSDART00000173998
si:dkey-23i12.7
chr13_-_37620091 0.28 ENSDART00000135875
ENSDART00000193270
ENSDART00000018064
zgc:152791
chr5_-_26834511 0.28 ENSDART00000136713
ENSDART00000192932
ENSDART00000113246
si:ch211-102c2.4
chr4_+_3358383 0.27 ENSDART00000075320
nicotinamide phosphoribosyltransferase a
chr22_-_15593824 0.27 ENSDART00000123125
tropomyosin 4a
chr1_+_34224360 0.27 ENSDART00000192938
ADP-ribosylation factor-like 6
chr12_+_16452575 0.27 ENSDART00000058665
kinesin family member 20Bb
chr7_+_31838320 0.27 ENSDART00000144679
ENSDART00000174217
ENSDART00000122506
myosin binding protein C, cardiac
chr23_-_25798099 0.27 ENSDART00000041833
fat storage-inducing transmembrane protein 2
chr15_+_15390882 0.27 ENSDART00000062024
carbonic anhydrase IV b
chr15_-_5815006 0.26 ENSDART00000102459
retinol binding protein 2a, cellular
chr17_-_24439672 0.26 ENSDART00000155020
WD repeat containing planar cell polarity effector
chr1_+_2190714 0.26 ENSDART00000132126
muscleblind-like splicing regulator 2
chr3_-_42125655 0.26 ENSDART00000040753
nudix (nucleoside diphosphate linked moiety X)-type motif 1
chr6_+_55174744 0.26 ENSDART00000023562
synaptotagmin 2
chr1_-_7894255 0.26 ENSDART00000167126
ENSDART00000145460
Ras association and DIL domains
chr12_+_16284086 0.25 ENSDART00000013360
ENSDART00000141169
protein phosphatase 1, regulatory subunit 3Cb
chr15_+_28096152 0.25 ENSDART00000100293
ENSDART00000140092
crystallin, beta B1, like 3
chr14_+_8475007 0.25 ENSDART00000148210
DnaJ (Hsp40) homolog, subfamily C, member 4
chr10_+_24627683 0.25 ENSDART00000112652
solute carrier family 46, member 3
chr23_+_44497701 0.25 ENSDART00000149903
si:ch73-375g18.1
chr21_+_10076203 0.25 ENSDART00000190383

chr21_-_5393125 0.25 ENSDART00000146061
proteasome 26S subunit, non-ATPase 5
chr16_+_23398369 0.25 ENSDART00000037694
S100 calcium binding protein A10b
chr4_-_779796 0.25 ENSDART00000128743
transmembrane protein 214
chr24_-_22756508 0.25 ENSDART00000035409
ENSDART00000146247
zinc finger, C2HC-type containing 1A
chr5_+_45918680 0.25 ENSDART00000036242
ankyrin repeat and death domain containing 1B
chr16_+_8668519 0.24 ENSDART00000172893
chemokine (C-C motif) receptor 2
chr17_-_14700889 0.24 ENSDART00000179975
protein tyrosine phosphatase type IVA, member 2a
chr8_+_45003659 0.24 ENSDART00000132663
si:ch211-163b2.4
chr25_-_15040369 0.24 ENSDART00000159342
ENSDART00000166490
paired box 6a
chr3_-_40202607 0.24 ENSDART00000074757
zinc finger protein 598
chr11_-_8269227 0.24 ENSDART00000127202
ENSDART00000158079
ENSDART00000158748
si:cabz01021067.1
Pim proto-oncogene, serine/threonine kinase, related 202
chr3_-_45308394 0.24 ENSDART00000155324
3-phosphoinositide dependent protein kinase 1a
chr4_+_5205265 0.24 ENSDART00000067382
polypeptide N-acetylgalactosaminyltransferase 8b, tandem duplicate 1
chr6_-_12456077 0.24 ENSDART00000190107
glycerol-3-phosphate dehydrogenase 2 (mitochondrial)
chr2_+_28453338 0.24 ENSDART00000020456
matrix metallopeptidase 15b
chr10_+_26634472 0.24 ENSDART00000143655
adhesion G protein-coupled receptor G4b

Network of associatons between targets according to the STRING database.

First level regulatory network of cdc5l

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0060631 regulation of meiosis I(GO:0060631)
0.2 0.6 GO:0007571 age-dependent general metabolic decline(GO:0007571)
0.2 0.5 GO:0071498 cellular response to fluid shear stress(GO:0071498)
0.2 1.3 GO:0048240 sperm capacitation(GO:0048240)
0.1 1.1 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.1 0.4 GO:0060292 long term synaptic depression(GO:0060292)
0.1 0.6 GO:0033152 immunoglobulin V(D)J recombination(GO:0033152)
0.1 0.3 GO:0010265 SCF complex assembly(GO:0010265)
0.1 0.5 GO:0021742 abducens nucleus development(GO:0021742)
0.1 0.5 GO:0046952 ketone body catabolic process(GO:0046952)
0.1 1.1 GO:0030719 P granule organization(GO:0030719)
0.1 0.3 GO:0003223 ventricular compact myocardium morphogenesis(GO:0003223)
0.1 0.5 GO:0007060 male meiosis chromosome segregation(GO:0007060)
0.1 0.6 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.1 0.3 GO:0033301 cell cycle comprising mitosis without cytokinesis(GO:0033301)
0.1 0.2 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.1 1.5 GO:0007286 spermatid development(GO:0007286)
0.1 0.3 GO:1902883 negative regulation of cellular response to oxidative stress(GO:1900408) negative regulation of response to oxidative stress(GO:1902883) regulation of oxidative stress-induced cell death(GO:1903201) negative regulation of oxidative stress-induced cell death(GO:1903202)
0.1 0.2 GO:2000434 regulation of protein neddylation(GO:2000434)
0.1 0.5 GO:0032917 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.1 0.5 GO:0036372 opsin transport(GO:0036372)
0.1 0.2 GO:0042117 monocyte activation(GO:0042117)
0.1 0.6 GO:0006267 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.1 0.3 GO:0008591 regulation of Wnt signaling pathway, calcium modulating pathway(GO:0008591) negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.1 0.5 GO:0006566 threonine metabolic process(GO:0006566) threonine catabolic process(GO:0006567)
0.1 0.3 GO:0003210 cardiac atrium formation(GO:0003210)
0.1 0.5 GO:0015800 acidic amino acid transport(GO:0015800) aspartate transport(GO:0015810) L-glutamate transport(GO:0015813) malate-aspartate shuttle(GO:0043490)
0.1 0.4 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.0 0.2 GO:0098529 neuromuscular junction development, skeletal muscle fiber(GO:0098529)
0.0 0.2 GO:2000171 negative regulation of dendrite development(GO:2000171)
0.0 0.7 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.0 0.5 GO:0071479 cellular response to ionizing radiation(GO:0071479)
0.0 0.2 GO:0015677 copper ion import(GO:0015677)
0.0 0.3 GO:0035627 ceramide transport(GO:0035627)
0.0 0.4 GO:0099550 trans-synaptic signalling, modulating synaptic transmission(GO:0099550)
0.0 0.3 GO:0071459 protein localization to kinetochore(GO:0034501) protein localization to chromosome, centromeric region(GO:0071459)
0.0 0.3 GO:0034389 lipid particle organization(GO:0034389)
0.0 0.3 GO:0046685 response to arsenic-containing substance(GO:0046685)
0.0 0.4 GO:2001238 positive regulation of extrinsic apoptotic signaling pathway(GO:2001238)
0.0 0.1 GO:2000257 regulation of protein activation cascade(GO:2000257)
0.0 0.1 GO:0044803 virion assembly(GO:0019068) virus maturation(GO:0019075) multi-organism membrane organization(GO:0044803) viral budding(GO:0046755) multi-organism organelle organization(GO:1902590) multi-organism membrane budding(GO:1902592)
0.0 0.1 GO:0065001 specification of axis polarity(GO:0065001)
0.0 0.1 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.0 0.5 GO:0050482 icosanoid secretion(GO:0032309) arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.0 0.3 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.2 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.2 GO:0060221 retinal rod cell differentiation(GO:0060221)
0.0 1.0 GO:0019915 lipid storage(GO:0019915)
0.0 0.2 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.0 0.1 GO:0000338 protein deneddylation(GO:0000338)
0.0 0.2 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.2 GO:1902267 polyamine transport(GO:0015846) polyamine transmembrane transport(GO:1902047) regulation of polyamine transmembrane transport(GO:1902267) positive regulation of polyamine transmembrane transport(GO:1902269)
0.0 0.2 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.0 0.5 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.6 GO:0060324 face development(GO:0060324)
0.0 0.7 GO:0006801 superoxide metabolic process(GO:0006801)
0.0 0.5 GO:0006208 pyrimidine nucleobase catabolic process(GO:0006208)
0.0 0.2 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.0 0.1 GO:0010633 negative regulation of epithelial cell migration(GO:0010633)
0.0 0.2 GO:0099517 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.0 0.6 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.4 GO:1900107 regulation of nodal signaling pathway(GO:1900107)
0.0 0.2 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.0 0.2 GO:1903426 regulation of reactive oxygen species biosynthetic process(GO:1903426)
0.0 0.1 GO:0071881 adenylate cyclase-inhibiting adrenergic receptor signaling pathway(GO:0071881)
0.0 0.7 GO:0007568 aging(GO:0007568)
0.0 0.1 GO:1902410 mitotic cytokinetic process(GO:1902410) mitotic cleavage furrow formation(GO:1903673)
0.0 0.5 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.0 0.8 GO:0033500 carbohydrate homeostasis(GO:0033500) glucose homeostasis(GO:0042593)
0.0 0.2 GO:0006283 transcription-coupled nucleotide-excision repair(GO:0006283)
0.0 0.1 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.0 0.1 GO:0021519 optic cup formation involved in camera-type eye development(GO:0003408) spinal cord association neuron specification(GO:0021519)
0.0 0.3 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.0 7.3 GO:0046777 protein autophosphorylation(GO:0046777)
0.0 0.6 GO:0048263 determination of dorsal identity(GO:0048263)
0.0 0.5 GO:0042073 intraciliary transport(GO:0042073)
0.0 1.9 GO:0003341 cilium movement(GO:0003341)
0.0 0.1 GO:1903358 regulation of Golgi organization(GO:1903358)
0.0 0.1 GO:0007624 ultradian rhythm(GO:0007624)
0.0 0.2 GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein(GO:0042531)
0.0 0.1 GO:0046654 tetrahydrofolate biosynthetic process(GO:0046654)
0.0 0.4 GO:0007622 rhythmic behavior(GO:0007622) circadian behavior(GO:0048512)
0.0 0.1 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.0 0.1 GO:0070291 N-acylethanolamine metabolic process(GO:0070291)
0.0 0.1 GO:0007508 larval development(GO:0002164) larval heart development(GO:0007508) angiogenesis involved in wound healing(GO:0060055)
0.0 0.2 GO:0060386 synapse assembly involved in innervation(GO:0060386)
0.0 0.1 GO:1901825 tetraterpenoid metabolic process(GO:0016108) tetraterpenoid biosynthetic process(GO:0016109) carotenoid metabolic process(GO:0016116) carotenoid biosynthetic process(GO:0016117) xanthophyll metabolic process(GO:0016122) xanthophyll biosynthetic process(GO:0016123) zeaxanthin metabolic process(GO:1901825) zeaxanthin biosynthetic process(GO:1901827)
0.0 0.1 GO:0046546 development of primary male sexual characteristics(GO:0046546)
0.0 0.2 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.0 0.2 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.0 0.2 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.5 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.1 GO:0032367 intracellular cholesterol transport(GO:0032367) positive regulation of lipid transport(GO:0032370)
0.0 0.1 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.0 0.2 GO:0001964 startle response(GO:0001964)
0.0 0.4 GO:2000045 regulation of G1/S transition of mitotic cell cycle(GO:2000045)
0.0 0.1 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.0 0.1 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.1 GO:0048339 paraxial mesoderm development(GO:0048339)
0.0 0.2 GO:0035999 tetrahydrofolate interconversion(GO:0035999)
0.0 0.1 GO:0051823 regulation of synapse structural plasticity(GO:0051823)
0.0 0.3 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.0 GO:0046653 tetrahydrofolate metabolic process(GO:0046653)
0.0 0.2 GO:0030325 adrenal gland development(GO:0030325)
0.0 0.1 GO:0043435 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.0 0.2 GO:0002115 store-operated calcium entry(GO:0002115)
0.0 0.0 GO:1904353 positive regulation of telomere maintenance(GO:0032206) regulation of telomere capping(GO:1904353) positive regulation of telomere capping(GO:1904355)
0.0 0.1 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0033391 chromatoid body(GO:0033391)
0.2 0.6 GO:0000333 telomerase catalytic core complex(GO:0000333)
0.2 1.1 GO:0036156 inner dynein arm(GO:0036156)
0.1 0.5 GO:0008537 proteasome activator complex(GO:0008537)
0.1 0.5 GO:0030896 checkpoint clamp complex(GO:0030896)
0.1 0.4 GO:0097519 DNA recombinase complex(GO:0097519)
0.1 0.5 GO:0005879 axonemal microtubule(GO:0005879)
0.1 0.3 GO:0097541 axonemal basal plate(GO:0097541)
0.1 0.7 GO:0001669 acrosomal vesicle(GO:0001669)
0.1 1.5 GO:0000795 synaptonemal complex(GO:0000795)
0.1 0.2 GO:0097255 R2TP complex(GO:0097255)
0.1 0.2 GO:0098556 cytoplasmic side of rough endoplasmic reticulum membrane(GO:0098556)
0.1 0.2 GO:0098574 cytoplasmic side of lysosomal membrane(GO:0098574)
0.0 0.1 GO:0043614 multi-eIF complex(GO:0043614)
0.0 1.1 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.1 GO:0005775 vacuolar lumen(GO:0005775) lysosomal lumen(GO:0043202)
0.0 0.2 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.6 GO:0042555 MCM complex(GO:0042555)
0.0 0.3 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.1 GO:0033186 CAF-1 complex(GO:0033186)
0.0 0.3 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.2 GO:0016234 inclusion body(GO:0016234)
0.0 0.3 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.4 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 1.9 GO:0031514 motile cilium(GO:0031514)
0.0 1.1 GO:0005811 lipid particle(GO:0005811)
0.0 0.1 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 0.1 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.1 GO:0090443 FAR/SIN/STRIPAK complex(GO:0090443)
0.0 0.7 GO:0031970 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.0 0.1 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.3 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.2 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.0 0.0 GO:0000126 transcription factor TFIIIB complex(GO:0000126)
0.0 0.3 GO:0098844 postsynaptic endocytic zone membrane(GO:0098844)
0.0 0.9 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.2 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.3 GO:0060170 ciliary membrane(GO:0060170)
0.0 0.2 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 0.2 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 0.1 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 0.2 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0 0.4 GO:1902711 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.0 0.1 GO:0033181 plasma membrane proton-transporting V-type ATPase complex(GO:0033181)
0.0 0.2 GO:0090568 nuclear transcriptional repressor complex(GO:0090568)
0.0 0.2 GO:0005869 dynactin complex(GO:0005869)
0.0 0.0 GO:0030689 Noc complex(GO:0030689)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0003721 telomerase RNA reverse transcriptase activity(GO:0003721)
0.2 0.5 GO:0070735 protein-glycine ligase activity(GO:0070735) tubulin-glycine ligase activity(GO:0070738)
0.1 0.4 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.1 0.6 GO:0043140 ATP-dependent 3'-5' DNA helicase activity(GO:0043140) single-stranded DNA-dependent ATP-dependent 3'-5' DNA helicase activity(GO:1990518)
0.1 0.6 GO:0004127 cytidylate kinase activity(GO:0004127)
0.1 0.5 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
0.1 0.5 GO:0008743 L-threonine 3-dehydrogenase activity(GO:0008743)
0.1 0.5 GO:0061133 endopeptidase activator activity(GO:0061133)
0.1 0.6 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.1 1.1 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.1 0.6 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.1 0.5 GO:0019809 polyamine binding(GO:0019808) spermidine binding(GO:0019809)
0.1 0.3 GO:1902387 ceramide transporter activity(GO:0035620) ceramide 1-phosphate binding(GO:1902387) ceramide 1-phosphate transporter activity(GO:1902388)
0.1 0.2 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.1 0.3 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.1 0.3 GO:0019992 diacylglycerol binding(GO:0019992)
0.1 0.2 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.1 0.2 GO:0016822 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.0 0.2 GO:0004134 glycogen debranching enzyme activity(GO:0004133) 4-alpha-glucanotransferase activity(GO:0004134) amylo-alpha-1,6-glucosidase activity(GO:0004135)
0.0 0.1 GO:0080132 fatty acid alpha-hydroxylase activity(GO:0080132)
0.0 0.2 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
0.0 0.2 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0 0.3 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.0 0.2 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.0 0.5 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.0 0.1 GO:1903136 cuprous ion binding(GO:1903136)
0.0 0.3 GO:0001217 bacterial-type RNA polymerase transcription factor activity, sequence-specific DNA binding(GO:0001130) bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding(GO:0001217)
0.0 0.1 GO:0033897 ribonuclease T2 activity(GO:0033897)
0.0 0.4 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 0.6 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.2 GO:0046592 polyamine oxidase activity(GO:0046592)
0.0 0.5 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.0 0.2 GO:0004475 mannose-1-phosphate guanylyltransferase activity(GO:0004475) mannose-phosphate guanylyltransferase activity(GO:0008905)
0.0 0.5 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 1.1 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.0 0.3 GO:0016933 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 0.2 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.0 0.2 GO:0004619 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619)
0.0 0.6 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.0 0.2 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.0 0.1 GO:0008459 chondroitin 6-sulfotransferase activity(GO:0008459)
0.0 0.1 GO:2001070 starch binding(GO:2001070)
0.0 0.1 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 1.3 GO:0043022 ribosome binding(GO:0043022)
0.0 0.1 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.0 0.3 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 0.4 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.5 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.2 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.1 GO:0008097 5S rRNA binding(GO:0008097)
0.0 0.2 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.5 GO:0004623 phospholipase A2 activity(GO:0004623)
0.0 0.1 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.0 0.1 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
0.0 0.1 GO:0052885 retinol isomerase activity(GO:0050251) all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity(GO:0052885)
0.0 0.1 GO:0031705 bombesin receptor binding(GO:0031705)
0.0 0.2 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
0.0 0.1 GO:0042834 peptidoglycan binding(GO:0042834)
0.0 0.1 GO:0019238 cyclohydrolase activity(GO:0019238)
0.0 0.1 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.1 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.0 0.1 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.0 0.1 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 1.1 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.0 GO:0016155 formyltetrahydrofolate dehydrogenase activity(GO:0016155)
0.0 0.1 GO:0003977 UDP-N-acetylglucosamine diphosphorylase activity(GO:0003977)
0.0 0.1 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.0 0.8 GO:0003678 DNA helicase activity(GO:0003678)
0.0 0.4 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.1 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.4 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.1 GO:0016312 inositol bisphosphate phosphatase activity(GO:0016312)
0.0 0.4 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.1 GO:0003691 double-stranded telomeric DNA binding(GO:0003691) single-stranded telomeric DNA binding(GO:0043047) sequence-specific single stranded DNA binding(GO:0098847)
0.0 0.2 GO:0033613 activating transcription factor binding(GO:0033613)
0.0 0.1 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.1 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.2 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.1 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 0.7 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.1 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 0.5 PID ERBB4 PATHWAY ErbB4 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.2 REACTOME DEFENSINS Genes involved in Defensins
0.0 0.6 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.6 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.4 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.2 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 1.0 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 0.1 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.1 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.7 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.6 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.0 0.5 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 0.1 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.2 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.4 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.3 REACTOME BOTULINUM NEUROTOXICITY Genes involved in Botulinum neurotoxicity
0.0 0.2 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.4 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0 0.2 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.1 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 0.2 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.1 REACTOME DOUBLE STRAND BREAK REPAIR Genes involved in Double-Strand Break Repair
0.0 0.1 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.3 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.1 REACTOME COMMON PATHWAY Genes involved in Common Pathway