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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for cdx1a+cdx1b

Z-value: 0.87

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Transcription factors associated with cdx1a+cdx1b

Gene Symbol Gene ID Gene Info
cdx1a
ENSDARG00000114554 caudal type homeobox 1a
cdx1b
ENSDARG00000116139 caudal type homeobox 1 b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
cdx1adr11_v1_chr14_+_3287740_32877400.371.3e-01Click!
cdx1bdr11_v1_chr21_-_43992027_439920270.048.7e-01Click!

Activity profile of cdx1a+cdx1b motif

Sorted Z-values of cdx1a+cdx1b motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_53468160 2.04 ENSDART00000143349
zgc:66455
zgc:66455
chr3_-_53091946 2.04 ENSDART00000187297
lpar2a
lysophosphatidic acid receptor 2a
chr1_-_13989643 1.88 ENSDART00000191046
elf2b
E74-like factor 2b (ets domain transcription factor)
chr15_-_28596507 1.48 ENSDART00000156800
si:ch211-225b7.5
si:ch211-225b7.5
chr3_+_49074008 1.48 ENSDART00000168864
zgc:112146
zgc:112146
chr20_+_52546186 1.44 ENSDART00000110777
ENSDART00000153377
ENSDART00000153013
ENSDART00000042704
eef1db
eukaryotic translation elongation factor 1 delta b (guanine nucleotide exchange protein)
chr24_-_9997948 1.26 ENSDART00000136274
si:ch211-146l10.7
si:ch211-146l10.7
chr10_-_21545091 1.15 ENSDART00000029122
ENSDART00000132207
zgc:165539
zgc:165539
chr12_+_3871452 1.11 ENSDART00000066546
nif3l1
NIF3 NGG1 interacting factor 3-like 1 (S. cerevisiae)
chr9_-_710896 1.11 ENSDART00000180478
ndufb3
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3
chr11_+_25257022 1.09 ENSDART00000156052
tp53inp2
tumor protein p53 inducible nuclear protein 2
chr20_-_43741159 1.09 ENSDART00000192621
si:dkeyp-50f7.2
si:dkeyp-50f7.2
chr18_-_14691727 1.08 ENSDART00000010129
pdf
peptide deformylase, mitochondrial
chr21_-_11855828 1.03 ENSDART00000081666
ube2r2
ubiquitin-conjugating enzyme E2R 2
chr10_+_44700103 1.00 ENSDART00000165999
scarb1
scavenger receptor class B, member 1
chr15_+_32405959 0.95 ENSDART00000177269
si:ch211-162k9.6
si:ch211-162k9.6
chr9_+_3282369 0.95 ENSDART00000044128
hat1
histone acetyltransferase 1
chr10_+_40321067 0.93 ENSDART00000109816
gltpb
glycolipid transfer protein b
chr5_-_1963498 0.91 ENSDART00000073462
rplp0
ribosomal protein, large, P0
chr6_+_120181 0.86 ENSDART00000151209
ENSDART00000185930
cdkn2d
cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
chr19_+_3840955 0.86 ENSDART00000172305
lsm10
LSM10, U7 small nuclear RNA associated
chr20_+_26880668 0.86 ENSDART00000077769
serpinb1
serpin peptidase inhibitor, clade B (ovalbumin), member 1
chr5_+_58687541 0.85 ENSDART00000083015
ENSDART00000181902
ccdc84
coiled-coil domain containing 84
chr14_-_45604667 0.84 ENSDART00000167016
si:ch211-276i12.9
si:ch211-276i12.9
chr6_-_6976096 0.81 ENSDART00000151822
ENSDART00000039443
ENSDART00000177960
tuba8l4
tubulin, alpha 8 like 4
chr2_-_5728843 0.81 ENSDART00000014020
sst2
somatostatin 2
chr24_-_10006158 0.78 ENSDART00000106244
zgc:171750
zgc:171750
chr5_-_9073433 0.78 ENSDART00000099891
atp5meb
ATP synthase membrane subunit eb
chr10_+_44699734 0.78 ENSDART00000167952
ENSDART00000158681
ENSDART00000190188
ENSDART00000168276
scarb1
scavenger receptor class B, member 1
chr1_+_8508753 0.76 ENSDART00000091683
alkbh5
alkB homolog 5, RNA demethylase
chr9_+_51891 0.76 ENSDART00000163529
zgc:158316
zgc:158316
chr5_+_70155935 0.73 ENSDART00000165570
rgs3a
regulator of G protein signaling 3a
chr20_-_13140309 0.73 ENSDART00000020703
ENSDART00000188594
ints7
integrator complex subunit 7
chr25_+_16080181 0.73 ENSDART00000061753
far1
fatty acyl CoA reductase 1
chr12_+_27022517 0.72 ENSDART00000152975
msl1b
male-specific lethal 1 homolog b (Drosophila)
chr24_-_10014512 0.71 ENSDART00000124341
ENSDART00000191630
zgc:171474
zgc:171474
chr3_-_29910547 0.69 ENSDART00000151501
RUNDC1
si:dkey-151m15.5
chr22_+_2512154 0.69 ENSDART00000097363
zgc:173726
zgc:173726
chr23_+_7379728 0.67 ENSDART00000012194
gata5
GATA binding protein 5
chr16_+_43344475 0.67 ENSDART00000085282
mrpl32
mitochondrial ribosomal protein L32
chr24_-_24114217 0.67 ENSDART00000160578
zgc:112982
zgc:112982
chr15_-_4580763 0.66 ENSDART00000008170
rffl
ring finger and FYVE-like domain containing E3 ubiquitin protein ligase
chr7_-_48263516 0.65 ENSDART00000006619
ENSDART00000142370
ENSDART00000148273
ENSDART00000147968
rbpms2b
RNA binding protein with multiple splicing 2b
chr15_+_32423801 0.65 ENSDART00000165591
si:dkey-285b23.3
si:dkey-285b23.3
chr10_-_15340362 0.65 ENSDART00000148119
ENSDART00000127277
ENSDART00000154037
ENSDART00000189109
pum3
pumilio RNA-binding family member 3
chr2_-_27975530 0.64 ENSDART00000020367
zgc:56556
zgc:56556
chr3_-_15999501 0.62 ENSDART00000160668
nme3
NME/NM23 nucleoside diphosphate kinase 3
chr7_+_52154215 0.61 ENSDART00000098712
TMEM208
zgc:77041
chr21_-_15929041 0.61 ENSDART00000080693
lhx5
LIM homeobox 5
chr12_-_13205854 0.59 ENSDART00000077829
pelo
pelota mRNA surveillance and ribosome rescue factor
chr21_+_20396858 0.59 ENSDART00000003299
ENSDART00000146615
zgc:103482
zgc:103482
chr11_-_25538341 0.57 ENSDART00000171560
si:dkey-245f22.3
si:dkey-245f22.3
chr24_-_6158933 0.57 ENSDART00000021609
gad2
glutamate decarboxylase 2
chr5_+_64856666 0.56 ENSDART00000050863
zgc:101858
zgc:101858
chr21_-_41838284 0.56 ENSDART00000141067
cct6a
chaperonin containing TCP1, subunit 6A (zeta 1)
chr15_+_42285643 0.54 ENSDART00000152731
scaf4b
SR-related CTD-associated factor 4b
chr23_+_28092083 0.53 ENSDART00000053958
c1galt1a
core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1a
chr18_-_44908479 0.52 ENSDART00000169636
si:ch211-71n6.4
si:ch211-71n6.4
chr24_+_26134029 0.52 ENSDART00000185134
tmtopsb
teleost multiple tissue opsin b
chr1_+_41466011 0.52 ENSDART00000135280
paip2b
poly(A) binding protein interacting protein 2B
chr11_+_44622472 0.51 ENSDART00000159068
ENSDART00000166323
ENSDART00000187753
rbm34
RNA binding motif protein 34
chr1_+_34496855 0.50 ENSDART00000012873
klf12a
Kruppel-like factor 12a
chr1_-_9249943 0.49 ENSDART00000055011
zgc:136472
zgc:136472
chr14_-_9056066 0.49 ENSDART00000139669
ENSDART00000138758
ENSDART00000041099
sybl1
synaptobrevin-like 1
chr2_+_26682913 0.48 ENSDART00000010683
ENSDART00000131411
ENSDART00000137933
impa1
inositol monophosphatase 1
chr15_-_23908779 0.48 ENSDART00000088808
usp32
ubiquitin specific peptidase 32
chr1_+_41465771 0.48 ENSDART00000010211
paip2b
poly(A) binding protein interacting protein 2B
chr14_-_4121052 0.48 ENSDART00000167074
irf2
interferon regulatory factor 2
chr24_+_30392834 0.48 ENSDART00000162555
dpyda.1
dihydropyrimidine dehydrogenase a, tandem duplicate 1
chr5_-_69499486 0.48 ENSDART00000023983
ENSDART00000180293
psat1
phosphoserine aminotransferase 1
chr14_-_41272034 0.47 ENSDART00000191709
ENSDART00000074438
cenpi
centromere protein I
chr21_+_41837610 0.46 ENSDART00000157974
rnf14
ring finger protein 14
chr5_-_67750907 0.45 ENSDART00000172097
b4galt4
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4
chr25_-_35047838 0.45 ENSDART00000155060
CU302436.3

chr14_-_15171435 0.45 ENSDART00000159148
ENSDART00000166622
si:dkey-77g12.1
si:dkey-77g12.1
chr7_+_73827805 0.44 ENSDART00000109316
zgc:173587
zgc:173587
chr23_+_44349252 0.44 ENSDART00000097644
ephb4b
eph receptor B4b
chr24_+_39105051 0.42 ENSDART00000115297
mss51
MSS51 mitochondrial translational activator
chr3_-_33437796 0.41 ENSDART00000075499
si:dkey-283b1.7
si:dkey-283b1.7
chr10_+_27068251 0.41 ENSDART00000012717
ehd1b
EH-domain containing 1b
chr12_-_48467733 0.41 ENSDART00000153126
ENSDART00000152895
ENSDART00000014190
sec31b
SEC31 homolog B, COPII coat complex component
chr13_-_5252559 0.41 ENSDART00000181652
si:dkey-78p8.1
si:dkey-78p8.1
chr14_+_15495088 0.40 ENSDART00000165765
ENSDART00000188577
si:dkey-203a12.6
si:dkey-203a12.6
chr2_+_2223837 0.40 ENSDART00000101038
ENSDART00000129354
tmie
transmembrane inner ear
chr23_-_24699400 0.39 ENSDART00000104031
sdf4
stromal cell derived factor 4
chr19_+_19652439 0.39 ENSDART00000165934
hibadha
3-hydroxyisobutyrate dehydrogenase a
chr25_-_20258508 0.38 ENSDART00000133860
ENSDART00000006840
ENSDART00000173434
dnm1l
dynamin 1-like
chr2_+_52847049 0.37 ENSDART00000121980
creb3l3b
cAMP responsive element binding protein 3-like 3b
chr7_+_66822229 0.37 ENSDART00000112109
lyve1a
lymphatic vessel endothelial hyaluronic receptor 1a
chr13_-_15793585 0.36 ENSDART00000145914
ENSDART00000010286
bag5
BCL2 associated athanogene 5
chr13_-_36034582 0.36 ENSDART00000133565
si:dkey-157l19.2
si:dkey-157l19.2
chr1_-_43892349 0.34 ENSDART00000148416
tacr3a
tachykinin receptor 3a
chr14_+_35369979 0.32 ENSDART00000144702
ENSDART00000169712
clint1a
clathrin interactor 1a
chr15_-_23908605 0.32 ENSDART00000185578
usp32
ubiquitin specific peptidase 32
chr16_+_42481447 0.31 ENSDART00000037401
herpud2
HERPUD family member 2
chr16_-_1757521 0.31 ENSDART00000124660
ascc3
activating signal cointegrator 1 complex subunit 3
chr12_-_2993095 0.31 ENSDART00000152316
si:dkey-202c14.3
si:dkey-202c14.3
chr25_-_27633115 0.31 ENSDART00000131539
hyal6
hyaluronoglucosaminidase 6
chr22_+_34616151 0.31 ENSDART00000155399
ENSDART00000104705
si:ch1073-214b20.2
si:ch1073-214b20.2
chr14_-_4120636 0.31 ENSDART00000059230
irf2
interferon regulatory factor 2
chr21_+_26720803 0.31 ENSDART00000053797
slc3a2b
solute carrier family 3 (amino acid transporter heavy chain), member 2b
chr5_-_31856681 0.31 ENSDART00000187817
pkn3
protein kinase N3
chr12_-_45238759 0.31 ENSDART00000154859
trim65
tripartite motif containing 65
chr13_-_25719628 0.30 ENSDART00000135383
si:dkey-192p21.6
si:dkey-192p21.6
chr10_-_3332362 0.30 ENSDART00000007577
ENSDART00000055140
tor4aa
torsin family 4, member Aa
chr23_+_309099 0.30 ENSDART00000134556
ENSDART00000055152
taf11
TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr9_-_16853462 0.29 ENSDART00000160273
CT573248.2

chr10_+_26926654 0.29 ENSDART00000078980
ENSDART00000100289
rab1bb
RAB1B, member RAS oncogene family b
chr10_+_26612321 0.29 ENSDART00000134322
fhl1b
four and a half LIM domains 1b
chr23_-_39751234 0.28 ENSDART00000160853
minos1
mitochondrial inner membrane organizing system 1
chr19_+_1873059 0.28 ENSDART00000145246
snrpd1
small nuclear ribonucleoprotein D1 polypeptide
chr11_-_44622240 0.28 ENSDART00000172258
ENSDART00000173340
tbce
tubulin folding cofactor E
chr12_+_23912074 0.28 ENSDART00000152864
svila
supervillin a
chr2_+_42592572 0.27 ENSDART00000179722
march11
membrane-associated ring finger (C3HC4) 11
chr7_-_44672095 0.27 ENSDART00000073745
cmtm4
CKLF-like MARVEL transmembrane domain containing 4
chr10_-_43721530 0.27 ENSDART00000025366
cetn3
centrin 3
chr6_-_40697585 0.27 ENSDART00000113196
si:ch211-157b11.14
si:ch211-157b11.14
chr20_-_14924858 0.27 ENSDART00000047039
dnm3a
dynamin 3a
chr17_-_43666166 0.27 ENSDART00000077990
egr2a
early growth response 2a
chr8_+_37755099 0.26 ENSDART00000075708
ENSDART00000140966
got1l1
glutamic-oxaloacetic transaminase 1 like 1
chr24_+_17270129 0.26 ENSDART00000186729
spag6
sperm associated antigen 6
chr6_+_49551614 0.26 ENSDART00000022581
rab22a
RAB22A, member RAS oncogene family
chr8_+_30709685 0.26 ENSDART00000133989
upb1
ureidopropionase, beta
chr5_-_16351306 0.26 ENSDART00000168643
CABZ01088700.1

chr25_+_17847054 0.26 ENSDART00000067290
PYURF
zgc:162634
chr10_-_10864331 0.25 ENSDART00000122657
nrarpa
NOTCH regulated ankyrin repeat protein a
chr20_-_14925281 0.25 ENSDART00000152641
dnm3a
dynamin 3a
chr4_-_8795250 0.24 ENSDART00000169823
pnpla3
patatin-like phospholipase domain containing 3
chr3_-_35554809 0.24 ENSDART00000010944
dctn5
dynactin 5
chr1_+_30103297 0.24 ENSDART00000146783
vps8
vacuolar protein sorting 8 homolog (S. cerevisiae)
chr10_-_31563049 0.23 ENSDART00000023575
robo3
roundabout, axon guidance receptor, homolog 3 (Drosophila)
chr23_-_18030399 0.23 ENSDART00000136967
pm20d1.1
peptidase M20 domain containing 1, tandem duplicate 1
chr18_+_14684115 0.23 ENSDART00000108469
spata2l
spermatogenesis associated 2-like
chr5_-_8406192 0.22 ENSDART00000159718
spef2
sperm flagellar 2
chr10_-_24371312 0.22 ENSDART00000149362
pitpnab
phosphatidylinositol transfer protein, alpha b
chr16_+_42471455 0.22 ENSDART00000166640
si:ch211-215k15.5
si:ch211-215k15.5
chr11_-_44622478 0.21 ENSDART00000171837
tbce
tubulin folding cofactor E
chr24_+_32592748 0.21 ENSDART00000188256
si:ch211-282b22.1
si:ch211-282b22.1
chr3_-_19200571 0.21 ENSDART00000131503
ENSDART00000012335
rfx1a
regulatory factor X, 1a (influences HLA class II expression)
chr14_-_12020653 0.20 ENSDART00000106654
znf711
zinc finger protein 711
chr15_+_29276508 0.20 ENSDART00000170537
ENSDART00000126559
rap1gap2a
RAP1 GTPase activating protein 2a
chr7_-_41693004 0.20 ENSDART00000121509
malrd1
MAM and LDL receptor class A domain containing 1
chr7_+_18989241 0.20 ENSDART00000053213
zgc:194252
zgc:194252
chr5_-_12713920 0.19 ENSDART00000099749
CLDN22
si:dkey-98f17.3
chr6_+_40629066 0.19 ENSDART00000103757
slc6a11a
solute carrier family 6 (neurotransmitter transporter), member 11a
chr10_-_35410518 0.19 ENSDART00000048430
gabrr3a
gamma-aminobutyric acid (GABA) A receptor, rho 3a
chr8_-_38159805 0.18 ENSDART00000112331
ENSDART00000180006
adgra2
adhesion G protein-coupled receptor A2
chr5_-_9625459 0.18 ENSDART00000143347
sh2b3
SH2B adaptor protein 3
chr16_-_24561354 0.18 ENSDART00000193278
ENSDART00000126274
si:ch211-79k12.2
si:ch211-79k12.2
chr11_-_36051004 0.17 ENSDART00000025033
gpx1a
glutathione peroxidase 1a
chr11_-_18323059 0.17 ENSDART00000182590
SFMBT1
Scm like with four mbt domains 1
chr11_-_21303946 0.17 ENSDART00000185786
RASSF5
si:dkey-85p17.3
chr10_-_34889053 0.17 ENSDART00000136966
ccdc169
coiled-coil domain containing 169
chr7_+_22823889 0.17 ENSDART00000127467
ENSDART00000148576
ENSDART00000149993
pygmb
phosphorylase, glycogen, muscle b
chr8_-_53169445 0.16 ENSDART00000144493
rbsn
rabenosyn, RAB effector
chr24_+_26402110 0.16 ENSDART00000133684
si:ch211-230g15.5
si:ch211-230g15.5
chr10_-_31562695 0.16 ENSDART00000186456
robo3
roundabout, axon guidance receptor, homolog 3 (Drosophila)
chr13_+_4405282 0.16 ENSDART00000148280
prr18
proline rich 18
chr10_-_29903165 0.16 ENSDART00000078800
lim2.1
lens intrinsic membrane protein 2.1
chr25_-_19433244 0.16 ENSDART00000154778
map1ab
microtubule-associated protein 1Ab
chr22_+_34615591 0.16 ENSDART00000189563
si:ch1073-214b20.2
si:ch1073-214b20.2
chr11_+_12052791 0.16 ENSDART00000158479
si:ch211-156l18.8
si:ch211-156l18.8
chr6_-_12588044 0.16 ENSDART00000047896
slc15a1b
solute carrier family 15 (oligopeptide transporter), member 1b
chr11_+_6116503 0.16 ENSDART00000176170
nr2f6b
nuclear receptor subfamily 2, group F, member 6b
chr5_-_23715861 0.16 ENSDART00000019992
gbgt1l1
globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 1
chr15_-_3956906 0.16 ENSDART00000171202
clrn1
clarin 1
chr10_-_44924289 0.16 ENSDART00000171267
tuba7l
tubulin, alpha 7 like
chr12_+_18744610 0.16 ENSDART00000153456
mkl1b
megakaryoblastic leukemia (translocation) 1b
chr25_+_29161609 0.16 ENSDART00000180752
pkmb
pyruvate kinase M1/2b
chr25_+_4750972 0.16 ENSDART00000168903
si:zfos-2372e4.1
si:zfos-2372e4.1
chr5_-_31857345 0.15 ENSDART00000112546
pkn3
protein kinase N3
chr8_+_18615938 0.15 ENSDART00000089161
si:ch211-232d19.4
si:ch211-232d19.4
chr25_-_18953322 0.15 ENSDART00000155927
si:ch211-68a17.7
si:ch211-68a17.7
chr7_+_50766094 0.15 ENSDART00000165037
si:ch73-380l10.2
si:ch73-380l10.2
chr21_+_11969603 0.15 ENSDART00000142247
ENSDART00000140652
mlnl
motilin-like
chr24_-_40009446 0.15 ENSDART00000087422
aoc1
amine oxidase, copper containing 1
chr16_+_13993285 0.15 ENSDART00000139130
ENSDART00000130353
si:dkey-85k15.7
fdps
si:dkey-85k15.7
farnesyl diphosphate synthase (farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase)
chr2_+_5927255 0.15 ENSDART00000152866
si:ch211-168b3.2
si:ch211-168b3.2
chr23_-_39959784 0.14 ENSDART00000115046
xcr1a.1
chemokine (C motif) receptor 1a, duplicate 1
chr14_-_31060082 0.14 ENSDART00000111601
ENSDART00000161113
mbnl3
muscleblind-like splicing regulator 3
chr5_-_30984271 0.14 ENSDART00000051392
spns3
spinster homolog 3 (Drosophila)
chr23_-_39959173 0.14 ENSDART00000077122
xcr1a.1
chemokine (C motif) receptor 1a, duplicate 1
chr20_+_52458765 0.14 ENSDART00000057980
tsta3
tissue specific transplantation antigen P35B
chr9_+_9441453 0.14 ENSDART00000081859
ENSDART00000188567
ENSDART00000143101
maats1
MYCBP-associated, testis expressed 1
chr2_+_14992879 0.13 ENSDART00000137546
pimr55
Pim proto-oncogene, serine/threonine kinase, related 55
chr19_+_4916233 0.13 ENSDART00000159512
ppp1r1b
protein phosphatase 1, regulatory (inhibitor) subunit 1B
chr2_-_17235891 0.13 ENSDART00000144251
artnb
artemin b
chr1_-_7603734 0.13 ENSDART00000009315
mxb
myxovirus (influenza) resistance B
chr1_-_56213723 0.13 ENSDART00000142505
ENSDART00000137237
si:dkey-76b14.2
si:dkey-76b14.2
chr22_-_10605045 0.13 ENSDART00000184812
bap1
BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
chr1_+_46194333 0.13 ENSDART00000010894
sox1b
SRY (sex determining region Y)-box 1b
chr15_-_19677511 0.13 ENSDART00000043743
si:dkey-4p15.3
si:dkey-4p15.3
chr2_-_19520324 0.13 ENSDART00000079877
pimr52
Pim proto-oncogene, serine/threonine kinase, related 52
chr13_+_45431660 0.12 ENSDART00000099950
syf2
SYF2 pre-mRNA-splicing factor
chr2_-_19520690 0.12 ENSDART00000133559
pimr52
Pim proto-oncogene, serine/threonine kinase, related 52
chr21_-_8153165 0.12 ENSDART00000182580
CABZ01074363.1

chr22_+_2403068 0.12 ENSDART00000132925
ENSDART00000132569
zgc:112977
zgc:112977
chr16_+_20934353 0.12 ENSDART00000052660
skap2
src kinase associated phosphoprotein 2
chr7_+_18075504 0.12 ENSDART00000173689
si:ch73-40a2.1
si:ch73-40a2.1
chr14_+_15597049 0.12 ENSDART00000159732
si:dkey-203a12.8
si:dkey-203a12.8

Network of associatons between targets according to the STRING database.

First level regulatory network of cdx1a+cdx1b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.8 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.4 2.0 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.2 0.8 GO:0035553 oxidative single-stranded RNA demethylation(GO:0035553)
0.2 0.6 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.2 0.7 GO:0048618 post-embryonic foregut morphogenesis(GO:0048618)
0.2 0.5 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.1 0.6 GO:0032790 ribosome disassembly(GO:0032790)
0.1 0.7 GO:0008591 regulation of Wnt signaling pathway, calcium modulating pathway(GO:0008591) negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.1 1.1 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.1 0.9 GO:0035627 ceramide transport(GO:0035627)
0.1 0.5 GO:0016267 O-glycan processing, core 1(GO:0016267)
0.1 0.7 GO:0051148 smooth muscle cell differentiation(GO:0051145) negative regulation of muscle cell differentiation(GO:0051148)
0.1 0.3 GO:0019482 beta-alanine metabolic process(GO:0019482) beta-alanine biosynthetic process(GO:0019483)
0.1 0.9 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.1 2.0 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 0.5 GO:0006212 uracil catabolic process(GO:0006212) uracil metabolic process(GO:0019860)
0.1 0.7 GO:2001270 negative regulation of execution phase of apoptosis(GO:1900118) regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270) negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.1 0.9 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.1 0.4 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.1 0.4 GO:1903146 regulation of mitophagy(GO:1903146)
0.1 0.7 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.1 0.4 GO:0006574 valine catabolic process(GO:0006574)
0.1 0.3 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.1 0.2 GO:0022009 central nervous system vasculogenesis(GO:0022009)
0.1 0.2 GO:0010896 regulation of triglyceride catabolic process(GO:0010896) positive regulation of triglyceride catabolic process(GO:0010898)
0.1 0.6 GO:0045948 positive regulation of translational initiation(GO:0045948)
0.1 0.2 GO:2000275 regulation of oxidative phosphorylation uncoupler activity(GO:2000275)
0.1 0.2 GO:0052575 carbohydrate localization(GO:0052575) carbohydrate storage(GO:0052576)
0.1 1.1 GO:0032981 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.3 GO:1902093 positive regulation of sperm motility(GO:1902093)
0.0 0.5 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 1.1 GO:0010508 positive regulation of autophagy(GO:0010508)
0.0 0.6 GO:0046051 UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
0.0 0.9 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.5 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.2 GO:0071800 podosome assembly(GO:0071800)
0.0 0.6 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.0 0.1 GO:0090435 protein targeting to nuclear inner membrane(GO:0036228) protein localization to nuclear envelope(GO:0090435)
0.0 0.6 GO:0008354 germ cell migration(GO:0008354)
0.0 0.1 GO:0035522 monoubiquitinated protein deubiquitination(GO:0035520) monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.0 0.2 GO:0007288 sperm axoneme assembly(GO:0007288)
0.0 0.8 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.1 GO:0003249 cell proliferation involved in heart valve morphogenesis(GO:0003249) regulation of cell proliferation involved in heart valve morphogenesis(GO:0003250) endocardial cell development(GO:0060958) cell proliferation involved in heart valve development(GO:2000793)
0.0 0.4 GO:0071679 commissural neuron axon guidance(GO:0071679)
0.0 0.2 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.6 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.0 0.1 GO:0046677 response to antibiotic(GO:0046677)
0.0 0.2 GO:0010269 response to selenium ion(GO:0010269)
0.0 0.3 GO:0060142 regulation of syncytium formation by plasma membrane fusion(GO:0060142)
0.0 0.4 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.7 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.0 0.1 GO:0014707 branchiomeric skeletal muscle development(GO:0014707)
0.0 0.1 GO:0097033 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0 0.2 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.0 0.1 GO:0045337 farnesyl diphosphate biosynthetic process(GO:0045337)
0.0 0.3 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.0 0.1 GO:0002164 larval development(GO:0002164) larval heart development(GO:0007508)
0.0 0.3 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.0 0.3 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.0 1.4 GO:0006414 translational elongation(GO:0006414)
0.0 0.1 GO:0010481 ventriculo bulbo valve development(GO:0003173) epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
0.0 0.1 GO:0086005 ventricular cardiac muscle cell action potential(GO:0086005)
0.0 0.1 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.0 0.1 GO:0032964 collagen biosynthetic process(GO:0032964)
0.0 0.4 GO:0031397 negative regulation of protein ubiquitination(GO:0031397)
0.0 0.2 GO:0006857 oligopeptide transport(GO:0006857)
0.0 0.7 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.0 0.3 GO:0014823 response to activity(GO:0014823)
0.0 0.3 GO:1990798 pancreas regeneration(GO:1990798)
0.0 0.4 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 0.9 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.0 0.5 GO:0018298 protein-chromophore linkage(GO:0018298)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.4 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.1 0.7 GO:0072487 MSL complex(GO:0072487)
0.1 0.6 GO:0097225 sperm midpiece(GO:0097225)
0.1 0.4 GO:0034715 pICln-Sm protein complex(GO:0034715)
0.1 0.6 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 0.8 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.2 GO:1990909 Wnt signalosome(GO:1990909)
0.0 1.8 GO:0005901 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.0 0.7 GO:0032039 integrator complex(GO:0032039)
0.0 0.6 GO:0098844 postsynaptic endocytic zone membrane(GO:0098844)
0.0 0.2 GO:0030897 HOPS complex(GO:0030897)
0.0 0.2 GO:0001891 phagocytic cup(GO:0001891)
0.0 1.1 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.1 GO:0044611 nuclear pore inner ring(GO:0044611)
0.0 0.4 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.1 GO:0044609 DBIRD complex(GO:0044609)
0.0 0.7 GO:0016605 PML body(GO:0016605)
0.0 0.1 GO:0035517 PR-DUB complex(GO:0035517)
0.0 0.7 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.7 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.3 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 0.9 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.4 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.2 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.1 GO:0000974 Prp19 complex(GO:0000974)
0.0 0.0 GO:0089717 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.0 0.5 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.4 GO:0043596 nuclear replication fork(GO:0043596)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.8 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.2 0.8 GO:1990931 RNA N6-methyladenosine dioxygenase activity(GO:1990931)
0.2 0.6 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.2 0.9 GO:1902387 ceramide transporter activity(GO:0035620) ceramide 1-phosphate binding(GO:1902387) ceramide 1-phosphate transporter activity(GO:1902388)
0.2 0.5 GO:0052834 inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.2 0.9 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.1 2.0 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.1 0.5 GO:0016263 glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity(GO:0016263) beta-1,3-galactosyltransferase activity(GO:0048531)
0.1 0.7 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.1 0.5 GO:0002061 uracil binding(GO:0002058) pyrimidine nucleobase binding(GO:0002061) dihydropyrimidine dehydrogenase (NADP+) activity(GO:0017113)
0.1 0.4 GO:0008442 3-hydroxyisobutyrate dehydrogenase activity(GO:0008442)
0.1 0.9 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.1 1.0 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.1 GO:0004337 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.0 0.3 GO:0004995 tachykinin receptor activity(GO:0004995)
0.0 0.5 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.4 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.1 GO:0031834 neurokinin receptor binding(GO:0031834) substance P receptor binding(GO:0031835)
0.0 0.2 GO:0004645 phosphorylase activity(GO:0004645) glycogen phosphorylase activity(GO:0008184)
0.0 1.4 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.2 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.2 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.1 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 0.2 GO:0004743 pyruvate kinase activity(GO:0004743)
0.0 0.3 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.0 0.2 GO:0071916 dipeptide transporter activity(GO:0042936) dipeptide transmembrane transporter activity(GO:0071916)
0.0 0.6 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.2 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.4 GO:0035497 cAMP response element binding(GO:0035497)
0.0 1.0 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.4 GO:0005003 ephrin receptor activity(GO:0005003)
0.0 0.5 GO:0008378 galactosyltransferase activity(GO:0008378)
0.0 0.5 GO:0004697 protein kinase C activity(GO:0004697) calcium-dependent protein kinase C activity(GO:0004698)
0.0 1.3 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)
0.0 1.0 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.2 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0 0.1 GO:0004994 somatostatin receptor activity(GO:0004994)
0.0 0.3 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.0 0.4 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.0 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 0.4 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.0 0.1 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.0 0.1 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.0 0.1 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 0.4 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.5 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 PID TNF PATHWAY TNF receptor signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.8 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.6 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 0.8 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.6 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 0.7 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.3 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.5 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.3 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 0.2 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.9 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 1.1 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.5 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.0 0.1 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.1 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.2 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 0.4 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 0.4 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.4 REACTOME APOPTOTIC EXECUTION PHASE Genes involved in Apoptotic execution phase
0.0 0.3 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening