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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for cebpa

Z-value: 1.05

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Transcription factors associated with cebpa

Gene Symbol Gene ID Gene Info
ENSDARG00000036074 CCAAT enhancer binding protein alpha

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
cebpadr11_v1_chr7_-_38087865_380878650.896.0e-07Click!

Activity profile of cebpa motif

Sorted Z-values of cebpa motif

Promoter Log-likelihood Transcript Gene Gene Info
chr9_-_1702648 3.72 ENSDART00000102934
heterogeneous nuclear ribonucleoprotein A3
chr8_-_50147948 2.88 ENSDART00000149010
haptoglobin
chr23_-_28692581 2.67 ENSDART00000078141
RIB43A domain with coiled-coils 1
chr4_-_41209037 2.53 ENSDART00000151948
si:ch211-73m21.1
chr1_-_29139141 2.38 ENSDART00000075546
ENSDART00000133246
heat shock transcription factor 2 binding protein
chr7_-_10560964 2.14 ENSDART00000172761
ENSDART00000170476
5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase)
chr25_+_1732838 2.11 ENSDART00000159555
ENSDART00000168161
fibulin 1
chr4_-_5652030 2.10 ENSDART00000010903
radial spoke head 9 homolog
chr11_-_6265574 2.08 ENSDART00000181974
ENSDART00000104405
chemokine (C-C motif) ligand 25b
chr7_+_22616212 2.04 ENSDART00000052844
claudin 7a
chr19_+_8606883 1.95 ENSDART00000054469
ENSDART00000185264
S100 calcium binding protein A10a
chr20_+_23440632 1.93 ENSDART00000180685
ENSDART00000042820
si:dkey-90m5.4
chr17_+_14425219 1.90 ENSDART00000153994
coiled-coil domain containing 175
chr4_+_842010 1.87 ENSDART00000067461
si:ch211-152c2.3
chr25_-_16146851 1.84 ENSDART00000104043
dickkopf WNT signaling pathway inhibitor 3b
chr21_+_22423286 1.84 ENSDART00000133190
calcyphosine-like b
chr6_+_515181 1.83 ENSDART00000171374
si:ch73-379f7.5
chr16_-_21785261 1.81 ENSDART00000078858
si:ch73-86n18.1
chr24_+_2843268 1.77 ENSDART00000170529
si:ch211-152c8.2
chr7_-_30932094 1.75 ENSDART00000057677
telomere repeat binding bouquet formation protein 2
chr6_-_49510553 1.75 ENSDART00000166238
ribosomal protein, large P2
chr14_+_46313396 1.71 ENSDART00000047525
crystallin, beta A1, like 1
chr6_-_19683406 1.67 ENSDART00000158041
cilia and flagella associated protein 52
chr7_-_39738460 1.66 ENSDART00000052201
coiled-coil domain containing 96
chr2_-_32505091 1.64 ENSDART00000141884
ENSDART00000056639
Fas apoptotic inhibitory molecule 2a
chr14_+_31657412 1.63 ENSDART00000105767
four and a half LIM domains 1a
chr25_+_36411624 1.56 ENSDART00000124347
ankyrin repeat domain 27 (VPS9 domain)
chr23_-_40814080 1.56 ENSDART00000135713
si:dkeyp-27c8.1
chr23_-_28486893 1.55 ENSDART00000191348
transmembrane protein 107 like
chr9_-_48736388 1.49 ENSDART00000022074
dehydrogenase/reductase (SDR family) member 9
chr10_+_39091353 1.49 ENSDART00000125986
si:ch73-1a9.4
chr3_+_36313532 1.49 ENSDART00000151305
solute carrier family 16, member 6b
chr21_+_38002879 1.48 ENSDART00000065183
claudin 2
chr4_-_14915268 1.48 ENSDART00000067040
si:dkey-180p18.9
chr9_-_32847642 1.48 ENSDART00000121506
hemopexin
chr5_+_66353750 1.47 ENSDART00000143410
si:ch211-261c8.5
chr7_+_19903924 1.47 ENSDART00000159112
si:ch211-285j22.3
chr4_-_193762 1.46 ENSDART00000169667
protein tyrosine phosphatase, receptor type, O
chr1_-_46244523 1.45 ENSDART00000143908
si:ch211-138g9.3
chr25_-_31629095 1.44 ENSDART00000170673
ENSDART00000166930
laminin, beta 1a
chr19_-_9472893 1.44 ENSDART00000045565
ENSDART00000137505
vesicle-associated membrane protein 1
chr18_+_1145571 1.42 ENSDART00000135055
REC114 meiotic recombination protein
chr14_+_36885524 1.42 ENSDART00000032547
leukocyte cell-derived chemotaxin 2 like
chr11_-_12379541 1.40 ENSDART00000171717
zgc:174353
chr20_-_52271262 1.40 ENSDART00000135463
rhophilin, Rho GTPase binding protein 1
chr17_-_31695217 1.38 ENSDART00000104332
ENSDART00000143090
lin-52 DREAM MuvB core complex component
chr1_-_59141715 1.38 ENSDART00000164941
ENSDART00000138870
si:ch1073-110a20.1
chr11_-_12530304 1.37 ENSDART00000143061
zgc:174354
chr8_-_23684659 1.37 ENSDART00000136865
complement factor properdin
chr3_-_57666518 1.35 ENSDART00000102062
TIMP metallopeptidase inhibitor 2b
chr20_-_32007209 1.34 ENSDART00000021575
androglobin
chr7_-_7845540 1.33 ENSDART00000166280
chemokine (C-X-C motif) ligand 8b, duplicate 1
chr3_-_39180048 1.33 ENSDART00000049720
cyclin-dependent kinase 21
chr8_-_51578926 1.33 ENSDART00000190625
ankyrin repeat domain 39
chr10_+_453619 1.31 ENSDART00000135598
zinc finger, DHHC-type containing 8a
chr11_-_3959477 1.29 ENSDART00000045971
polybromo 1
chr17_+_6625717 1.26 ENSDART00000190753
ENSDART00000181298

chr9_+_32073606 1.26 ENSDART00000184170
ENSDART00000180355
ENSDART00000110204
ENSDART00000123278
phosphoinositide kinase, FYVE finger containing
chr7_+_19904136 1.26 ENSDART00000173452
si:ch211-285j22.3
chr11_-_25733910 1.25 ENSDART00000171935
bromodomain and PHD finger containing, 3a
chr8_-_13972626 1.24 ENSDART00000144296
serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
chr20_+_1121458 1.24 ENSDART00000064472
proline-rich nuclear receptor coactivator 1
chr21_-_22715297 1.23 ENSDART00000065548
complement component 1, q subcomponent, B chain
chr1_-_59139599 1.23 ENSDART00000152233
si:ch1073-110a20.3
chr25_+_14109626 1.21 ENSDART00000109883
actin, alpha, cardiac muscle 1c
chr4_-_11403811 1.21 ENSDART00000067272
ENSDART00000140018
Pim proto-oncogene, serine/threonine kinase, related 173
chr15_+_36309070 1.20 ENSDART00000157034
geminin coiled-coil domain containing
chr20_-_52271015 1.18 ENSDART00000074307
rhophilin, Rho GTPase binding protein 1
chr11_-_3959889 1.18 ENSDART00000159683
polybromo 1
chr17_+_1323699 1.14 ENSDART00000172540
adenylosuccinate synthase like 1
chr11_+_35364445 1.14 ENSDART00000125766
CaM kinase-like vesicle-associated b
chr1_+_34203817 1.12 ENSDART00000191432
ENSDART00000046094
ADP-ribosylation factor-like 6
chr19_-_44054930 1.11 ENSDART00000151084
ENSDART00000150991
ENSDART00000005191
ubiquinol-cytochrome c reductase binding protein
chr1_-_55270966 1.11 ENSDART00000152807
si:ch211-286b5.5
chr15_-_4969525 1.10 ENSDART00000157223
lipoyl(octanoyl) transferase 2
chr3_+_40809011 1.09 ENSDART00000033713
actin related protein 2/3 complex, subunit 1B
chr16_+_30575901 1.09 ENSDART00000077231
melanocortin 2 receptor
chr17_+_443264 1.08 ENSDART00000159086
zgc:195050
chr12_+_31616412 1.07 ENSDART00000124439
carboxypeptidase N, polypeptide 1
chr25_-_19443421 1.07 ENSDART00000067362
cocaine- and amphetamine-regulated transcript 2
chr23_-_28808480 1.06 ENSDART00000078167
DNA fragmentation factor, alpha polypeptide
chr22_+_26703026 1.06 ENSDART00000158756
CREB binding protein a
chr11_+_3959495 1.05 ENSDART00000122953
guanine nucleotide binding protein-like 3 (nucleolar)
chr21_+_45502621 1.05 ENSDART00000166719
si:dkey-223p19.2
chr3_-_40955780 1.05 ENSDART00000130130
cytochrome P450, family 3, subfamily c, polypeptide 3
chr3_-_13068189 1.04 ENSDART00000167180
protein kinase, cAMP-dependent, regulatory, type I, beta
chr22_+_1796057 1.04 ENSDART00000170834
zinc finger protein 1179
chr22_-_18491813 1.04 ENSDART00000105419
si:ch211-212d10.2
chr25_-_32751982 1.03 ENSDART00000012862
ISL LIM homeobox 2a
chr22_-_26236188 1.03 ENSDART00000162640
ENSDART00000167169
ENSDART00000138595
complement component c3b, tandem duplicate 1
chr16_+_40576679 1.03 ENSDART00000169412
ENSDART00000193464
cyclin E2
chr1_-_11075403 1.02 ENSDART00000102903
ENSDART00000170290
dystrophin
chr24_-_25184553 1.01 ENSDART00000166917
phosphatidylinositol-specific phospholipase C, X domain containing 2
chr3_-_16055432 1.00 ENSDART00000123621
ENSDART00000023859
ATPase H+ transporting V0 subunit ca
chr1_-_59116617 1.00 ENSDART00000137471
ENSDART00000140490
si:zfos-2330d3.7
chr4_-_12725513 1.00 ENSDART00000132286
microsomal glutathione S-transferase 1.2
chr10_-_42776344 0.98 ENSDART00000190653
ENSDART00000130229
WD repeat domain 45
chr23_-_4915118 0.97 ENSDART00000060714
ATPase H+ transporting accessory protein 1a
chr14_-_17576391 0.97 ENSDART00000161355
ENSDART00000168959
ring finger protein 4
chr20_+_25563105 0.97 ENSDART00000063100
cytochrome P450, family 2, subfamily P, polypeptide 6
chr1_+_52563298 0.96 ENSDART00000142465
ATP-binding cassette, sub-family A (ABC1), member 1A
chr1_+_34224360 0.96 ENSDART00000192938
ADP-ribosylation factor-like 6
chr14_+_21106444 0.96 ENSDART00000075744
ENSDART00000132363
aldolase b, fructose-bisphosphate
chr10_+_9159279 0.95 ENSDART00000064968
RasGEF domain family, member 1Bb
chr16_-_13789908 0.94 ENSDART00000138540
tweety family member 1
chr5_+_7989210 0.94 ENSDART00000168071
glial cell derived neurotrophic factor b
chr17_-_14613711 0.93 ENSDART00000157345
serine dehydratase-like
chr23_+_4373360 0.92 ENSDART00000144061
protein tyrosine phosphatase domain containing 1b
chr22_-_36875264 0.92 ENSDART00000137548
kininogen 1
chr20_+_7584211 0.92 ENSDART00000132481
ENSDART00000127975
ENSDART00000144551
biogenesis of lysosomal organelles complex-1, subunit 2
chr16_-_4640539 0.91 ENSDART00000076955
ENSDART00000131949
cytochrome P450, family 4, subfamily T, polypeptide 8
chr7_-_72352043 0.91 ENSDART00000163536
mucin 5f
chr14_-_25949713 0.91 ENSDART00000181455
secreted protein, acidic, cysteine-rich (osteonectin)
chr19_-_9662958 0.91 ENSDART00000041094
chloride channel, voltage-sensitive 1a
chr13_-_20540790 0.90 ENSDART00000131467
si:ch1073-126c3.2
chr7_-_7823662 0.89 ENSDART00000167652
chemokine (C-X-C motif) ligand 8b, duplicate 3
chr4_+_52347226 0.88 ENSDART00000171626
si:dkeyp-107f9.2
chr13_+_28495419 0.88 ENSDART00000025583
fibroblast growth factor 8a
chr16_-_27442344 0.88 ENSDART00000027545
endoplasmic reticulum protein 44
chr9_-_31741731 0.87 ENSDART00000135022
sodium leak channel, non-selective
chr8_+_471342 0.87 ENSDART00000167205
nudix (nucleoside diphosphate linked moiety X)-type motif 12
chr3_+_24556640 0.87 ENSDART00000159405
SP110 nuclear body protein, tandem duplicate 2
chr21_+_22846757 0.87 ENSDART00000185766
baculoviral IAP repeat containing 2
chr23_+_9220436 0.87 ENSDART00000033663
ENSDART00000139870
ribosomal protein S21
chr14_-_3268155 0.85 ENSDART00000177244
platelet-derived growth factor receptor, beta polypeptide
chr7_+_24496894 0.85 ENSDART00000149994
negative elongation factor complex member A
chr25_-_36361697 0.84 ENSDART00000152388
si:ch211-113a14.22
chr14_-_7137808 0.83 ENSDART00000054803
tRNA phosphotransferase 1
chr10_-_17103651 0.83 ENSDART00000108959
ring finger protein 208
chr1_+_10051763 0.82 ENSDART00000011701
fibrinogen beta chain
chr15_+_4969128 0.81 ENSDART00000062856
ring finger protein 169
chr12_-_15620090 0.81 ENSDART00000038032
acyl-CoA binding domain containing 4
chr10_-_16470648 0.81 ENSDART00000149104
fibrillin 2a
chr20_+_6659770 0.80 ENSDART00000192135
tensin 3, tandem duplicate 2
chr20_+_32118559 0.80 ENSDART00000026273
CD164 molecule, sialomucin
chr23_+_27675581 0.80 ENSDART00000127198
ribosomal protein S26
chr23_+_45282858 0.80 ENSDART00000162353

chr5_+_8919698 0.80 ENSDART00000046440
1-acylglycerol-3-phosphate O-acyltransferase 9, like
chr12_+_32073660 0.79 ENSDART00000153245
ENSDART00000153268
syntaxin binding protein 4
chr4_-_57572054 0.78 ENSDART00000158610
Pim proto-oncogene, serine/threonine kinase, related 168
chr4_+_71989418 0.77 ENSDART00000170996
poly(ADP-ribose) polymerase family member 11
chr13_-_46917098 0.77 ENSDART00000183453
solute carrier family 29 (equilibrative nucleoside transporter), member 1a
chr5_+_17727310 0.77 ENSDART00000147657
fibrosin-like 1
chr2_+_49864219 0.77 ENSDART00000187744
ribosomal protein L37
chr7_-_72277269 0.77 ENSDART00000161914
ENSDART00000183927
solute carrier family 35 (GDP-fucose transporter), member C1
chr16_+_44906324 0.77 ENSDART00000074960
cd22 molecule
chr9_+_3388099 0.76 ENSDART00000019910
distal-less homeobox 1a
chr11_-_44163164 0.76 ENSDART00000047126
chloride channel, voltage-sensitive 4
chr23_-_4925641 0.76 ENSDART00000140861
ENSDART00000060718
tafazzin
chr25_-_13320986 0.76 ENSDART00000169238
si:ch211-194m7.8
chr9_-_34915351 0.76 ENSDART00000100728
ENSDART00000139608
UPF3A, regulator of nonsense mediated mRNA decay
chr1_-_10071422 0.76 ENSDART00000135522
ENSDART00000033118
fibrinogen alpha chain
chr3_+_52475058 0.75 ENSDART00000035867
si:ch211-241f5.3
chr24_-_17049270 0.75 ENSDART00000175508
methionine sulfoxide reductase B2
chr10_+_2981090 0.74 ENSDART00000111830
zinc finger, FYVE domain containing 16
chr21_-_45077429 0.74 ENSDART00000187268
ENSDART00000191003
Rap guanine nucleotide exchange factor (GEF) 6
chr11_+_24900123 0.73 ENSDART00000044987
ENSDART00000148023
translocase of inner mitochondrial membrane 17 homolog A (yeast)
chr21_+_4540127 0.73 ENSDART00000043431
nucleoporin 188
chr19_+_5674907 0.73 ENSDART00000042189
pyruvate dehydrogenase kinase, isozyme 2b
chr23_-_45439903 0.73 ENSDART00000170729
nephronectin
chr17_+_30587333 0.73 ENSDART00000156500
NHS-like 1a
chr7_-_59564011 0.73 ENSDART00000186053
zgc:112271
chr13_+_46927350 0.73 ENSDART00000165041
ENSDART00000167931
mitochondrial translational release factor 1-like
chr12_-_46959990 0.72 ENSDART00000084557
phospholysine phosphohistidine inorganic pyrophosphate phosphatase
chr23_-_7755373 0.72 ENSDART00000162868
protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2
chr3_-_22212764 0.72 ENSDART00000155490
microtubule-associated protein tau b
chr21_+_18353703 0.71 ENSDART00000181396
ENSDART00000166359
si:ch73-287m6.1
chr17_-_23412705 0.71 ENSDART00000126995
si:ch211-149k12.3
chr1_-_56032619 0.71 ENSDART00000143793
complement component c3a, duplicate 4
chr6_+_2093206 0.71 ENSDART00000114314
transglutaminase 2b
chr14_-_25949951 0.71 ENSDART00000141304
secreted protein, acidic, cysteine-rich (osteonectin)
chr9_+_2522797 0.71 ENSDART00000186786
ENSDART00000147034
G protein-coupled receptor 155a
chr6_-_13200585 0.71 ENSDART00000185321
eukaryotic translation elongation factor 1 beta 2
chr25_+_24616717 0.71 ENSDART00000089113
ankyrin repeat and BTB (POZ) domain containing 2b
chr12_+_46960579 0.71 ENSDART00000149032
ornithine aminotransferase
chr12_+_15002757 0.70 ENSDART00000135036
myosin light chain, phosphorylatable, fast skeletal muscle b
chr2_+_6127593 0.70 ENSDART00000184007
fizzy/cell division cycle 20 related 1b
chr11_-_42980535 0.70 ENSDART00000181160
ENSDART00000192064

chr11_+_3281899 0.70 ENSDART00000181012
matrix metallopeptidase 19
chr4_-_12723585 0.70 ENSDART00000185639
microsomal glutathione S-transferase 1.2
chr24_-_26485098 0.70 ENSDART00000135496
ENSDART00000009609
ENSDART00000133782
ENSDART00000141029
ENSDART00000113739
eukaryotic translation initiation factor 5A
chr12_+_15008582 0.69 ENSDART00000003847
myosin light chain, phosphorylatable, fast skeletal muscle b
chr22_-_26865181 0.69 ENSDART00000138311
heme oxygenase 2a
chr22_+_16320076 0.68 ENSDART00000164161
oxysterol binding protein-like 1A
chr1_-_35916247 0.68 ENSDART00000181541
SMAD family member 1
chr25_-_32311048 0.68 ENSDART00000181806
ENSDART00000086334

chr21_-_22928214 0.68 ENSDART00000182760
duboraya
chr13_-_25842074 0.67 ENSDART00000015154
poly(A) polymerase gamma
chr15_+_28202170 0.67 ENSDART00000077736
vitronectin a
chr7_+_42935126 0.67 ENSDART00000157747

chr22_-_26865361 0.66 ENSDART00000182504
heme oxygenase 2a
chr15_-_30832897 0.66 ENSDART00000152330
musashi RNA-binding protein 2b
chr11_-_38914265 0.65 ENSDART00000141229
si:ch211-122l14.4
chr6_-_41021571 0.65 ENSDART00000103776
haloacid dehalogenase-like hydrolase domain containing 3
chr17_+_10318071 0.65 ENSDART00000161844
forkhead box A1
chr14_+_21107032 0.64 ENSDART00000138319
ENSDART00000139103
ENSDART00000184735
aldolase b, fructose-bisphosphate
chr3_-_29925482 0.64 ENSDART00000151525
granulin a
chr25_+_31323978 0.64 ENSDART00000067030
lymphocyte-specific protein 1
chr17_-_6519423 0.63 ENSDART00000175626

chr15_-_23814330 0.62 ENSDART00000153843
si:ch211-167j9.5

Network of associatons between targets according to the STRING database.

First level regulatory network of cebpa

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.1 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.7 2.1 GO:2000471 regulation of hematopoietic stem cell migration(GO:2000471)
0.6 1.8 GO:0070197 telomere localization(GO:0034397) telomere tethering at nuclear periphery(GO:0034398) meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic telomere clustering(GO:0045141) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome localization to nuclear envelope involved in homologous chromosome segregation(GO:0090220) chromosome attachment to the nuclear envelope(GO:0097240)
0.4 1.2 GO:2000257 regulation of protein activation cascade(GO:2000257)
0.4 1.1 GO:2000374 oxygen metabolic process(GO:0072592) regulation of oxygen metabolic process(GO:2000374) positive regulation of oxygen metabolic process(GO:2000376)
0.3 1.3 GO:0032206 positive regulation of telomere maintenance(GO:0032206) regulation of telomere capping(GO:1904353) positive regulation of telomere capping(GO:1904355)
0.3 1.3 GO:0030091 protein repair(GO:0030091)
0.3 0.9 GO:0061217 regulation of morphogenesis of a branching structure(GO:0060688) positive regulation of mesonephros development(GO:0061213) regulation of mesonephros development(GO:0061217) regulation of kidney development(GO:0090183) positive regulation of kidney development(GO:0090184) regulation of branching involved in ureteric bud morphogenesis(GO:0090189) positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.3 2.1 GO:0009396 folic acid-containing compound biosynthetic process(GO:0009396)
0.3 0.9 GO:0019364 pyridine nucleotide catabolic process(GO:0019364) NAD catabolic process(GO:0019677) pyridine-containing compound catabolic process(GO:0072526)
0.3 1.7 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.2 0.7 GO:0070126 mitochondrial translational termination(GO:0070126)
0.2 1.0 GO:0010874 regulation of cholesterol efflux(GO:0010874)
0.2 1.4 GO:0055016 hypochord development(GO:0055016)
0.2 1.2 GO:1903251 multi-ciliated epithelial cell differentiation(GO:1903251)
0.2 0.9 GO:0009097 isoleucine metabolic process(GO:0006549) isoleucine biosynthetic process(GO:0009097)
0.2 0.7 GO:0061341 non-canonical Wnt signaling pathway involved in heart development(GO:0061341)
0.2 1.3 GO:0006788 heme oxidation(GO:0006788)
0.2 1.3 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.2 0.9 GO:0010882 regulation of cardiac muscle contraction by calcium ion signaling(GO:0010882)
0.2 0.9 GO:0060546 negative regulation of necroptotic process(GO:0060546) negative regulation of necrotic cell death(GO:0060547)
0.2 0.9 GO:0014909 smooth muscle cell migration(GO:0014909)
0.2 1.4 GO:0030262 apoptotic DNA fragmentation(GO:0006309) cellular component disassembly involved in execution phase of apoptosis(GO:0006921) apoptotic nuclear changes(GO:0030262)
0.2 0.6 GO:0006145 purine nucleobase catabolic process(GO:0006145)
0.2 1.9 GO:0031125 rRNA 3'-end processing(GO:0031125)
0.2 2.5 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.2 1.4 GO:0055011 atrial cardiac muscle cell differentiation(GO:0055011)
0.2 0.8 GO:0072530 purine-containing compound transmembrane transport(GO:0072530)
0.1 0.4 GO:0034138 chemokine production(GO:0032602) toll-like receptor 3 signaling pathway(GO:0034138)
0.1 1.6 GO:0003209 cardiac atrium morphogenesis(GO:0003209)
0.1 1.3 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.1 0.7 GO:2001293 malonyl-CoA metabolic process(GO:2001293)
0.1 0.8 GO:0034244 negative regulation of DNA-templated transcription, elongation(GO:0032785) negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.1 1.5 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.1 1.1 GO:0008343 adult feeding behavior(GO:0008343)
0.1 0.9 GO:1900047 negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.1 1.0 GO:0048845 venous blood vessel morphogenesis(GO:0048845)
0.1 0.8 GO:0015862 uridine transport(GO:0015862) pyrimidine nucleoside transport(GO:0015864)
0.1 0.8 GO:0035881 amacrine cell differentiation(GO:0035881)
0.1 1.2 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.1 1.6 GO:0072378 blood coagulation, fibrin clot formation(GO:0072378)
0.1 0.7 GO:1904668 positive regulation of ubiquitin protein ligase activity(GO:1904668)
0.1 1.5 GO:0042572 retinol metabolic process(GO:0042572)
0.1 1.6 GO:0098927 early endosome to late endosome transport(GO:0045022) vesicle-mediated transport between endosomal compartments(GO:0098927)
0.1 0.5 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.1 0.4 GO:0086005 ventricular cardiac muscle cell action potential(GO:0086005)
0.1 1.0 GO:0071941 nitrogen cycle metabolic process(GO:0071941)
0.1 0.5 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.1 0.5 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.1 0.9 GO:1902038 positive regulation of hematopoietic stem cell differentiation(GO:1902038)
0.1 0.7 GO:0045905 positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
0.1 0.4 GO:0010561 negative regulation of glycoprotein biosynthetic process(GO:0010561) negative regulation of amyloid precursor protein biosynthetic process(GO:0042985) negative regulation of glycoprotein metabolic process(GO:1903019)
0.1 0.4 GO:0003418 chondrocyte differentiation involved in endochondral bone morphogenesis(GO:0003413) growth plate cartilage chondrocyte differentiation(GO:0003418)
0.1 1.2 GO:0044154 histone H3-K14 acetylation(GO:0044154)
0.1 0.4 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.1 0.8 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024) CDP-diacylglycerol metabolic process(GO:0046341)
0.1 1.6 GO:0016203 muscle attachment(GO:0016203)
0.1 0.5 GO:0006574 valine catabolic process(GO:0006574)
0.1 0.8 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.1 1.2 GO:0035493 SNARE complex assembly(GO:0035493)
0.1 0.6 GO:0071340 skeletal muscle acetylcholine-gated channel clustering(GO:0071340)
0.1 0.6 GO:0043982 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.1 0.6 GO:0009253 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.1 0.6 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.1 0.7 GO:0055129 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.1 1.3 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.1 0.3 GO:0051876 pigment granule dispersal(GO:0051876)
0.1 0.5 GO:0032367 intracellular cholesterol transport(GO:0032367)
0.1 0.8 GO:0032048 cardiolipin metabolic process(GO:0032048) phosphatidylglycerol metabolic process(GO:0046471)
0.1 1.3 GO:0018149 peptide cross-linking(GO:0018149)
0.1 0.4 GO:2000580 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.1 0.2 GO:0035751 regulation of lysosomal lumen pH(GO:0035751)
0.1 3.5 GO:0070830 apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830)
0.1 0.9 GO:0042119 granulocyte activation(GO:0036230) neutrophil activation(GO:0042119)
0.1 0.5 GO:0032889 regulation of vacuole fusion, non-autophagic(GO:0032889)
0.1 1.6 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.1 1.0 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.1 1.6 GO:0048752 semicircular canal morphogenesis(GO:0048752)
0.1 0.4 GO:0097241 hematopoietic stem cell migration to bone marrow(GO:0097241)
0.1 0.8 GO:0045738 negative regulation of DNA repair(GO:0045738) negative regulation of double-strand break repair(GO:2000780)
0.1 0.3 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.1 0.4 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.1 0.4 GO:1903426 regulation of reactive oxygen species biosynthetic process(GO:1903426)
0.1 0.6 GO:0048319 axial mesoderm morphogenesis(GO:0048319)
0.1 0.5 GO:0034205 beta-amyloid formation(GO:0034205) amyloid precursor protein catabolic process(GO:0042987)
0.1 0.5 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.1 0.3 GO:0045745 positive regulation of G-protein coupled receptor protein signaling pathway(GO:0045745)
0.1 0.6 GO:0000710 meiotic mismatch repair(GO:0000710)
0.1 0.2 GO:0006560 proline metabolic process(GO:0006560) proline catabolic process(GO:0006562)
0.1 2.1 GO:0051904 melanosome transport(GO:0032402) pigment granule transport(GO:0051904)
0.1 0.5 GO:2001238 positive regulation of extrinsic apoptotic signaling pathway(GO:2001238)
0.1 0.4 GO:0044211 CTP salvage(GO:0044211)
0.1 0.7 GO:0021988 olfactory bulb development(GO:0021772) olfactory lobe development(GO:0021988)
0.1 0.9 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.0 0.1 GO:0006824 cobalt ion transport(GO:0006824) cobalamin transport(GO:0015889)
0.0 1.0 GO:0002574 thrombocyte differentiation(GO:0002574)
0.0 0.3 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 1.1 GO:0033555 multicellular organismal response to stress(GO:0033555)
0.0 0.5 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.0 0.1 GO:0036462 TRAIL-activated apoptotic signaling pathway(GO:0036462)
0.0 1.5 GO:0021587 cerebellum morphogenesis(GO:0021587)
0.0 0.2 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.0 0.5 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.5 GO:0001541 ovarian follicle development(GO:0001541) ovulation cycle process(GO:0022602) ovulation cycle(GO:0042698)
0.0 0.8 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.4 GO:0048659 smooth muscle cell proliferation(GO:0048659)
0.0 0.4 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.0 0.4 GO:0050962 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.4 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 0.5 GO:0033198 response to ATP(GO:0033198)
0.0 0.2 GO:0061577 calcium ion transmembrane transport via high voltage-gated calcium channel(GO:0061577) regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1902514)
0.0 0.5 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.0 0.6 GO:1903288 positive regulation of sodium ion transport(GO:0010765) positive regulation of potassium ion transport(GO:0043268) positive regulation of potassium ion transmembrane transport(GO:1901381) positive regulation of sodium ion transmembrane transport(GO:1902307) regulation of potassium ion import(GO:1903286) positive regulation of potassium ion import(GO:1903288) positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.0 0.3 GO:0032088 negative regulation of NF-kappaB transcription factor activity(GO:0032088)
0.0 0.5 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.0 0.7 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.6 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.5 GO:0050994 regulation of lipid catabolic process(GO:0050994)
0.0 0.9 GO:0006879 cellular iron ion homeostasis(GO:0006879)
0.0 0.8 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.0 0.3 GO:0048635 negative regulation of muscle organ development(GO:0048635)
0.0 1.6 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.0 0.2 GO:0051454 pH elevation(GO:0045852) intracellular pH elevation(GO:0051454)
0.0 0.2 GO:0006833 water transport(GO:0006833)
0.0 0.1 GO:0006370 7-methylguanosine mRNA capping(GO:0006370)
0.0 0.3 GO:0010889 regulation of sequestering of triglyceride(GO:0010889) positive regulation of sequestering of triglyceride(GO:0010890) sequestering of triglyceride(GO:0030730)
0.0 0.6 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
0.0 1.3 GO:0042738 drug metabolic process(GO:0017144) drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738)
0.0 0.7 GO:0006378 mRNA polyadenylation(GO:0006378) RNA polyadenylation(GO:0043631)
0.0 0.2 GO:0045955 negative regulation of calcium ion-dependent exocytosis(GO:0045955) negative regulation of regulated secretory pathway(GO:1903306)
0.0 0.3 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.0 1.8 GO:0090090 negative regulation of canonical Wnt signaling pathway(GO:0090090)
0.0 1.1 GO:0071391 cellular response to estrogen stimulus(GO:0071391)
0.0 0.2 GO:0032098 regulation of appetite(GO:0032098)
0.0 0.4 GO:0043507 activation of JUN kinase activity(GO:0007257) positive regulation of JUN kinase activity(GO:0043507)
0.0 1.4 GO:0072376 protein activation cascade(GO:0072376)
0.0 3.0 GO:0006821 chloride transport(GO:0006821)
0.0 0.6 GO:0070831 basement membrane assembly(GO:0070831)
0.0 0.1 GO:0030326 embryonic limb morphogenesis(GO:0030326)
0.0 0.6 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.0 0.7 GO:0030574 collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
0.0 0.7 GO:0045727 positive regulation of translation(GO:0045727)
0.0 0.1 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.0 0.4 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.4 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.7 GO:0001878 response to yeast(GO:0001878)
0.0 0.4 GO:0046330 positive regulation of JNK cascade(GO:0046330)
0.0 0.3 GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625)
0.0 0.7 GO:0010906 regulation of glucose metabolic process(GO:0010906)
0.0 0.1 GO:0006537 glutamate biosynthetic process(GO:0006537) glutamine catabolic process(GO:0006543)
0.0 0.8 GO:0003014 renal system process(GO:0003014)
0.0 0.3 GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.0 0.1 GO:1901998 toxin transport(GO:1901998)
0.0 0.1 GO:0001909 leukocyte mediated cytotoxicity(GO:0001909)
0.0 1.3 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 1.8 GO:0002088 lens development in camera-type eye(GO:0002088)
0.0 0.7 GO:0006414 translational elongation(GO:0006414)
0.0 0.5 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.0 1.0 GO:0015718 monocarboxylic acid transport(GO:0015718)
0.0 0.6 GO:0042129 regulation of T cell proliferation(GO:0042129)
0.0 0.2 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.5 GO:0030851 granulocyte differentiation(GO:0030851)
0.0 0.1 GO:0099525 synaptic vesicle docking(GO:0016081) presynaptic dense core granule exocytosis(GO:0099525)
0.0 0.1 GO:0046677 response to antibiotic(GO:0046677)
0.0 0.1 GO:0032656 interleukin-13 production(GO:0032616) regulation of interleukin-13 production(GO:0032656)
0.0 0.4 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 0.7 GO:0060215 primitive hemopoiesis(GO:0060215)
0.0 0.3 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.0 0.7 GO:0060395 SMAD protein signal transduction(GO:0060395)
0.0 0.1 GO:0072422 signal transduction involved in DNA integrity checkpoint(GO:0072401) signal transduction involved in DNA damage checkpoint(GO:0072422) signal transduction involved in G2 DNA damage checkpoint(GO:0072425)
0.0 0.5 GO:0001707 mesoderm formation(GO:0001707)
0.0 0.1 GO:0048680 positive regulation of axon regeneration(GO:0048680) positive regulation of neuron projection regeneration(GO:0070572)
0.0 0.4 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.2 GO:0044872 lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
0.0 0.2 GO:0002027 regulation of heart rate(GO:0002027)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.1 GO:0001534 radial spoke(GO:0001534)
0.5 1.6 GO:0005577 fibrinogen complex(GO:0005577)
0.3 2.1 GO:0016586 RSC complex(GO:0016586)
0.2 0.7 GO:0044611 nuclear pore inner ring(GO:0044611)
0.2 1.0 GO:0033181 plasma membrane proton-transporting V-type ATPase complex(GO:0033181)
0.2 0.6 GO:0005880 nuclear microtubule(GO:0005880)
0.1 0.4 GO:0098556 cytoplasmic side of rough endoplasmic reticulum membrane(GO:0098556)
0.1 0.4 GO:0031417 NatC complex(GO:0031417)
0.1 0.9 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.1 0.5 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.1 1.2 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.1 0.6 GO:1990923 PET complex(GO:1990923)
0.1 1.3 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.1 1.0 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 0.3 GO:0043202 vacuolar lumen(GO:0005775) lysosomal lumen(GO:0043202)
0.1 0.9 GO:0042788 polysomal ribosome(GO:0042788)
0.1 0.5 GO:0018444 translation release factor complex(GO:0018444)
0.1 0.7 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.1 1.5 GO:0036038 MKS complex(GO:0036038)
0.1 0.8 GO:0032021 NELF complex(GO:0032021)
0.1 2.0 GO:0005605 basal lamina(GO:0005605) laminin complex(GO:0043256)
0.1 0.6 GO:0016012 sarcoglycan complex(GO:0016012)
0.1 0.9 GO:0000930 gamma-tubulin complex(GO:0000930)
0.1 1.4 GO:0060170 ciliary membrane(GO:0060170)
0.1 0.4 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.1 1.0 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.1 1.2 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.1 0.5 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 1.4 GO:0090568 nuclear transcriptional repressor complex(GO:0090568)
0.1 1.1 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.1 1.0 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1 1.1 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.1 0.8 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.1 0.8 GO:0044545 NSL complex(GO:0044545)
0.1 2.2 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 0.3 GO:0005663 DNA replication factor C complex(GO:0005663)
0.0 0.2 GO:0097268 cytoophidium(GO:0097268)
0.0 0.3 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.5 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.7 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.5 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 0.7 GO:0005844 polysome(GO:0005844)
0.0 0.3 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.1 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.0 0.3 GO:0071914 prominosome(GO:0071914)
0.0 0.2 GO:0071203 WASH complex(GO:0071203)
0.0 0.4 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.1 GO:0061702 inflammasome complex(GO:0061702)
0.0 0.8 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.6 GO:0016282 eukaryotic 43S preinitiation complex(GO:0016282)
0.0 0.2 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.6 GO:0005771 multivesicular body(GO:0005771)
0.0 0.7 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.6 GO:0000795 synaptonemal complex(GO:0000795)
0.0 0.2 GO:0036156 inner dynein arm(GO:0036156)
0.0 1.7 GO:0097014 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.0 0.4 GO:0005869 dynactin complex(GO:0005869)
0.0 1.1 GO:0016592 mediator complex(GO:0016592)
0.0 0.6 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 0.2 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.0 23.9 GO:0005615 extracellular space(GO:0005615)
0.0 0.8 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.4 GO:0001518 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.0 1.6 GO:0030018 Z disc(GO:0030018)
0.0 0.2 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.8 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.0 1.3 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 1.6 GO:0005770 late endosome(GO:0005770)
0.0 0.1 GO:0032420 stereocilium(GO:0032420)
0.0 0.7 GO:0005643 nuclear pore(GO:0005643)
0.0 0.4 GO:0031012 extracellular matrix(GO:0031012)
0.0 0.1 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.1 GO:0090533 sodium:potassium-exchanging ATPase complex(GO:0005890) cation-transporting ATPase complex(GO:0090533)
0.0 0.7 GO:0000123 histone acetyltransferase complex(GO:0000123)
0.0 0.1 GO:0005845 mRNA cap binding complex(GO:0005845)
0.0 0.1 GO:0070552 BRISC complex(GO:0070552)
0.0 6.7 GO:0005576 extracellular region(GO:0005576)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.2 GO:0005153 interleukin-8 receptor binding(GO:0005153)
0.4 1.8 GO:0039706 co-receptor binding(GO:0039706)
0.4 1.1 GO:0033819 lipoyl(octanoyl) transferase activity(GO:0033819)
0.2 0.9 GO:0030116 glial cell-derived neurotrophic factor receptor binding(GO:0030116)
0.2 0.9 GO:0004579 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.2 1.3 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.2 1.3 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.2 0.9 GO:0048407 platelet-derived growth factor-activated receptor activity(GO:0005017) platelet-derived growth factor binding(GO:0048407)
0.2 0.8 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.2 0.6 GO:0016920 pyroglutamyl-peptidase activity(GO:0016920)
0.2 1.6 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.2 1.0 GO:0090554 phospholipid-translocating ATPase activity(GO:0004012) phosphatidylcholine-translocating ATPase activity(GO:0090554) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.2 0.6 GO:0004485 methylcrotonoyl-CoA carboxylase activity(GO:0004485)
0.2 1.5 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.2 0.9 GO:0016841 ammonia-lyase activity(GO:0016841)
0.2 0.7 GO:0004427 inorganic diphosphatase activity(GO:0004427) protein histidine phosphatase activity(GO:0101006)
0.2 0.9 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.2 0.7 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.2 0.8 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.1 1.0 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.1 1.0 GO:0098809 nitrite reductase activity(GO:0098809)
0.1 0.4 GO:0005499 vitamin D binding(GO:0005499)
0.1 0.7 GO:1990757 anaphase-promoting complex binding(GO:0010997) ubiquitin ligase activator activity(GO:1990757)
0.1 0.6 GO:0008745 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
0.1 1.7 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 0.5 GO:0097016 L27 domain binding(GO:0097016)
0.1 0.5 GO:0008442 3-hydroxyisobutyrate dehydrogenase activity(GO:0008442)
0.1 1.2 GO:0008079 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.1 1.1 GO:0004977 melanocortin receptor activity(GO:0004977)
0.1 0.7 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.1 0.3 GO:0033897 ribonuclease T2 activity(GO:0033897)
0.1 2.0 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.1 0.9 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.1 0.9 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.1 0.4 GO:0070052 collagen V binding(GO:0070052)
0.1 0.8 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.1 1.4 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.1 1.2 GO:0043994 H3 histone acetyltransferase activity(GO:0010484) histone acetyltransferase activity (H3-K23 specific)(GO:0043994)
0.1 0.5 GO:0004966 galanin receptor activity(GO:0004966)
0.1 0.7 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.1 1.3 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.1 0.4 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.1 0.3 GO:0030228 lipoprotein particle receptor activity(GO:0030228)
0.1 0.4 GO:0050218 propionate-CoA ligase activity(GO:0050218)
0.1 0.3 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.1 2.0 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.1 1.0 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.1 0.9 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) cysteine-type endopeptidase regulator activity involved in apoptotic process(GO:0043028)
0.1 0.5 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 3.1 GO:0003823 antigen binding(GO:0003823)
0.1 1.3 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.1 0.3 GO:0097108 hedgehog family protein binding(GO:0097108)
0.1 0.3 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
0.1 0.9 GO:0051879 Hsp90 protein binding(GO:0051879)
0.1 0.5 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.1 0.9 GO:0043015 gamma-tubulin binding(GO:0043015)
0.1 0.7 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.1 1.1 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.1 0.2 GO:0003884 D-amino-acid oxidase activity(GO:0003884)
0.1 0.3 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.1 2.7 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 0.4 GO:0004849 uridine kinase activity(GO:0004849)
0.1 1.4 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.1 1.8 GO:0005518 collagen binding(GO:0005518)
0.1 0.3 GO:0031769 glucagon receptor binding(GO:0031769)
0.1 2.1 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 0.4 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 1.3 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.5 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.0 0.2 GO:0002151 G-quadruplex RNA binding(GO:0002151)
0.0 0.2 GO:0070891 peptidoglycan binding(GO:0042834) lipoteichoic acid binding(GO:0070891)
0.0 0.2 GO:0004362 glutathione-disulfide reductase activity(GO:0004362)
0.0 0.2 GO:0003883 CTP synthase activity(GO:0003883)
0.0 1.3 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.4 GO:0031994 insulin-like growth factor I binding(GO:0031994) insulin-like growth factor II binding(GO:0031995)
0.0 4.6 GO:0004866 endopeptidase inhibitor activity(GO:0004866)
0.0 1.6 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.5 GO:0004931 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 0.4 GO:0016889 endodeoxyribonuclease activity, producing 3'-phosphomonoesters(GO:0016889)
0.0 0.6 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 1.0 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 1.8 GO:0044325 ion channel binding(GO:0044325)
0.0 0.6 GO:0019869 chloride channel inhibitor activity(GO:0019869) potassium channel inhibitor activity(GO:0019870)
0.0 0.8 GO:0005338 nucleotide-sugar transmembrane transporter activity(GO:0005338)
0.0 0.3 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.6 GO:0030983 mismatched DNA binding(GO:0030983)
0.0 0.7 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.3 GO:0004438 phosphatidylinositol-3-phosphatase activity(GO:0004438)
0.0 0.1 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.0 0.5 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0 0.2 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 2.4 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 0.3 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.7 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 1.4 GO:0005178 integrin binding(GO:0005178)
0.0 0.3 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.2 GO:0015250 water channel activity(GO:0015250)
0.0 0.3 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 0.7 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.7 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.3 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.2 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.0 1.1 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 4.9 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.2 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 1.1 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 1.8 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.4 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.7 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 1.7 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.6 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.0 0.2 GO:0030552 cAMP binding(GO:0030552)
0.0 0.6 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.7 GO:0043022 ribosome binding(GO:0043022)
0.0 0.1 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.0 GO:1990715 mRNA CDS binding(GO:1990715)
0.0 0.1 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.0 2.0 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.3 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.2 GO:0031628 opioid receptor binding(GO:0031628)
0.0 0.1 GO:0004359 glutaminase activity(GO:0004359)
0.0 1.1 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 0.2 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.2 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.4 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 0.8 GO:0009055 electron carrier activity(GO:0009055)
0.0 0.2 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.2 GO:0016502 purinergic nucleotide receptor activity(GO:0001614) nucleotide receptor activity(GO:0016502)
0.0 0.1 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 0.1 GO:0016838 carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.0 0.5 GO:0019239 deaminase activity(GO:0019239)
0.0 0.1 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 0.3 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 0.4 GO:0005109 frizzled binding(GO:0005109)
0.0 0.1 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.1 GO:0016408 C-acyltransferase activity(GO:0016408)
0.0 2.1 GO:0046982 protein heterodimerization activity(GO:0046982)
0.0 3.9 GO:0005198 structural molecule activity(GO:0005198)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.5 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.1 2.0 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.1 0.9 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 1.0 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.6 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.7 PID ALK2 PATHWAY ALK2 signaling events
0.0 2.0 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.8 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.8 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway
0.0 0.4 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.7 PID BMP PATHWAY BMP receptor signaling
0.0 4.2 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 2.1 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.4 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 1.1 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 3.0 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.2 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.3 PID RHOA PATHWAY RhoA signaling pathway
0.0 0.3 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.3 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 0.2 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 0.6 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.3 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.3 PID INSULIN PATHWAY Insulin Pathway
0.0 0.3 PID ATR PATHWAY ATR signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.1 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.2 1.4 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.2 1.6 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.1 2.2 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.1 1.2 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.1 0.6 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.1 1.4 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.1 1.3 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.1 1.4 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1 1.1 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1 0.2 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 1.0 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.1 1.6 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.1 0.4 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.1 0.4 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.1 2.7 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.4 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 3.3 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 1.0 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.9 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.5 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.4 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 0.9 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.4 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.6 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.3 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.4 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.0 3.2 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 0.8 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0 1.9 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.7 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 1.5 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 1.3 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.6 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.3 REACTOME FATTY ACYL COA BIOSYNTHESIS Genes involved in Fatty Acyl-CoA Biosynthesis
0.0 1.2 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 0.3 REACTOME POL SWITCHING Genes involved in Polymerase switching
0.0 0.3 REACTOME MUSCLE CONTRACTION Genes involved in Muscle contraction
0.0 0.2 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.4 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.3 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.4 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.1 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.6 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 0.1 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.2 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.8 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis
0.0 0.2 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.1 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.1 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters