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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for cebpd

Z-value: 0.59

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Transcription factors associated with cebpd

Gene Symbol Gene ID Gene Info
cebpd
ENSDARG00000087303 CCAAT enhancer binding protein delta

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
cebpddr11_v1_chr24_+_35564668_35564668-0.302.3e-01Click!

Activity profile of cebpd motif

Sorted Z-values of cebpd motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr7_+_46020508 2.06 ENSDART00000170294
ccne1
cyclin E1
chr7_+_46019780 1.79 ENSDART00000163991
ccne1
cyclin E1
chr5_+_22974019 1.69 ENSDART00000147157
ENSDART00000020434
brwd3
bromodomain and WD repeat domain containing 3
chr6_+_10333920 1.45 ENSDART00000151667
ENSDART00000151477
cobll1a
cordon-bleu WH2 repeat protein-like 1a
chr19_-_25113660 1.41 ENSDART00000035538
ptp4a3
protein tyrosine phosphatase type IVA, member 3
chr12_+_4920451 1.27 ENSDART00000171525
ENSDART00000159986
plekhm1
pleckstrin homology domain containing, family M (with RUN domain) member 1
chr6_+_23810529 1.19 ENSDART00000166921
glulb
glutamate-ammonia ligase (glutamine synthase) b
chr5_-_15283509 1.16 ENSDART00000052712
gnb1l
guanine nucleotide binding protein (G protein), beta polypeptide 1-like
chr13_+_40437550 1.13 ENSDART00000057090
ENSDART00000167859
got1
glutamic-oxaloacetic transaminase 1, soluble
chr21_+_17051478 1.09 ENSDART00000047201
ENSDART00000161650
ENSDART00000167298
atp2a2a
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2a
chr6_+_44197348 1.06 ENSDART00000075486
ppp4r2b
protein phosphatase 4, regulatory subunit 2b
chr6_+_44197099 1.03 ENSDART00000124168
ppp4r2b
protein phosphatase 4, regulatory subunit 2b
chr6_+_11397269 1.00 ENSDART00000114260
senp2
SUMO1/sentrin/SMT3 specific peptidase 2
chr7_+_39418869 0.89 ENSDART00000169195
CT030188.1

chr19_-_20446756 0.89 ENSDART00000140711
tbc1d5
TBC1 domain family, member 5
chr9_-_53062083 0.88 ENSDART00000122155
zmp:0000000936
zmp:0000000936
chr7_+_67733759 0.84 ENSDART00000172015
cyb5b
cytochrome b5 type B
chr14_-_5642371 0.83 ENSDART00000183859
ENSDART00000054876
npm1b
nucleophosmin 1b
chr8_+_42917515 0.83 ENSDART00000021715
slc23a2
solute carrier family 23 (ascorbic acid transporter), member 2
chr6_+_8314451 0.81 ENSDART00000147793
ENSDART00000183688
gcdha
glutaryl-CoA dehydrogenase a
chr19_+_43341115 0.81 ENSDART00000145846
ENSDART00000102384
sesn2
sestrin 2
chr18_-_15551360 0.80 ENSDART00000159915
ENSDART00000172690
ppfibp1b
PTPRF interacting protein, binding protein 1b (liprin beta 1)
chr14_+_21699129 0.78 ENSDART00000073707
stx3a
syntaxin 3A
chr19_+_43341424 0.78 ENSDART00000134815
sesn2
sestrin 2
chr11_+_13176568 0.77 ENSDART00000125371
ENSDART00000123257
mknk1
MAP kinase interacting serine/threonine kinase 1
chr9_+_24065855 0.76 ENSDART00000161468
ENSDART00000171577
ENSDART00000172743
ENSDART00000159324
ENSDART00000079689
ENSDART00000023196
ENSDART00000101577
lrrfip1a
leucine rich repeat (in FLII) interacting protein 1a
chr6_+_8315050 0.73 ENSDART00000189987
gcdha
glutaryl-CoA dehydrogenase a
chr5_+_8196264 0.73 ENSDART00000174564
ENSDART00000161261
lmbrd2a
LMBR1 domain containing 2a
chr9_-_9225980 0.72 ENSDART00000180301
cbsb
cystathionine-beta-synthase b
chr5_-_54395488 0.72 ENSDART00000160781
zmynd19
zinc finger, MYND-type containing 19
chr18_+_7553950 0.72 ENSDART00000193420
ENSDART00000062143
zgc:77650
zgc:77650
chr5_+_51111343 0.72 ENSDART00000092002
pomt1
protein-O-mannosyltransferase 1
chr16_-_27138478 0.71 ENSDART00000147438
tmem245
transmembrane protein 245
chr16_-_7793457 0.70 ENSDART00000113483
trim71
tripartite motif containing 71, E3 ubiquitin protein ligase
chr18_-_37252036 0.69 ENSDART00000132230
six5
SIX homeobox 5
chr13_+_30035253 0.69 ENSDART00000181303
ENSDART00000057525
ENSDART00000136622
dnajb12a
DnaJ (Hsp40) homolog, subfamily B, member 12a
chr5_+_51111766 0.69 ENSDART00000188552
pomt1
protein-O-mannosyltransferase 1
chr8_+_26874924 0.68 ENSDART00000141794
rimkla
ribosomal modification protein rimK-like family member A
chr17_-_17759138 0.66 ENSDART00000157128
ENSDART00000123845
adck1
aarF domain containing kinase 1
chr5_-_69948099 0.65 ENSDART00000034639
ENSDART00000191111
ugt2a4
UDP glucuronosyltransferase 2 family, polypeptide A4
chr19_-_15192638 0.63 ENSDART00000048151
phactr4a
phosphatase and actin regulator 4a
chr14_+_21699414 0.63 ENSDART00000169942
stx3a
syntaxin 3A
chr12_+_13205955 0.63 ENSDART00000092906
ppp1cab
protein phosphatase 1, catalytic subunit, alpha isozyme b
chr20_-_33675676 0.61 ENSDART00000147168
rock2b
rho-associated, coiled-coil containing protein kinase 2b
chr8_-_11324143 0.61 ENSDART00000008215
pip5k1bb
phosphatidylinositol-4-phosphate 5-kinase, type I, beta b
chr2_-_54387550 0.61 ENSDART00000097388
napgb
N-ethylmaleimide-sensitive factor attachment protein, gamma b
chr14_+_3507326 0.60 ENSDART00000159326
gstp1
glutathione S-transferase pi 1
chr2_-_4032732 0.60 ENSDART00000158335
rab18b
RAB18B, member RAS oncogene family
chr4_-_4261673 0.60 ENSDART00000150694
cd9b
CD9 molecule b
chr2_-_37277626 0.59 ENSDART00000135340
nadkb
NAD kinase b
chr12_-_17592215 0.59 ENSDART00000134597
usp42
ubiquitin specific peptidase 42
chr16_-_9830451 0.58 ENSDART00000148528
grhl2a
grainyhead-like transcription factor 2a
chr5_-_48680580 0.57 ENSDART00000031194
lysmd3
LysM, putative peptidoglycan-binding, domain containing 3
chr5_-_23574234 0.57 ENSDART00000002453
cwc15
CWC15 spliceosome-associated protein homolog (S. cerevisiae)
chr9_-_31915423 0.56 ENSDART00000060051
fgf14
fibroblast growth factor 14
chr5_-_43682930 0.56 ENSDART00000075017
si:dkey-40c11.1
si:dkey-40c11.1
chr16_-_42770064 0.54 ENSDART00000112879
slc4a7
solute carrier family 4, sodium bicarbonate cotransporter, member 7
chr10_+_45248326 0.54 ENSDART00000159797
zmiz2
zinc finger, MIZ-type containing 2
chr2_-_7246848 0.53 ENSDART00000146434
zgc:153115
zgc:153115
chr24_-_31123365 0.53 ENSDART00000182947
tmem56a
transmembrane protein 56a
chr25_-_12805295 0.52 ENSDART00000157629
ca5a
carbonic anhydrase Va
chr22_-_16377960 0.51 ENSDART00000168170
ttc39c
tetratricopeptide repeat domain 39C
chr22_-_16377666 0.49 ENSDART00000161878
ttc39c
tetratricopeptide repeat domain 39C
chr22_-_10158038 0.47 ENSDART00000047444
rbck1
RanBP-type and C3HC4-type zinc finger containing 1
chr11_+_43751263 0.47 ENSDART00000163843
zgc:153431
zgc:153431
chr15_+_24676905 0.46 ENSDART00000078014
ENSDART00000143137
poldip2
polymerase (DNA-directed), delta interacting protein 2
chr19_-_37508571 0.46 ENSDART00000018255
ilf2
interleukin enhancer binding factor 2
chr23_+_38957472 0.46 ENSDART00000193836
ATP9A
ATPase phospholipid transporting 9A (putative)
chr11_+_31323746 0.46 ENSDART00000180220
ENSDART00000189937
sipa1l2
signal-induced proliferation-associated 1 like 2
chr8_+_17884569 0.45 ENSDART00000134660
slc44a5b
solute carrier family 44, member 5b
chr8_-_35960987 0.45 ENSDART00000160503
slc15a4
solute carrier family 15 (oligopeptide transporter), member 4
chr7_-_37895771 0.44 ENSDART00000084282
papd5
PAP associated domain containing 5
chr20_-_35508805 0.41 ENSDART00000169538
adgrf3b
adhesion G protein-coupled receptor F3b
chr21_+_30721733 0.41 ENSDART00000040443
zgc:110224
zgc:110224
chr16_-_7828838 0.41 ENSDART00000191434
ENSDART00000108653
tcaim
T cell activation inhibitor, mitochondrial
chr14_-_12071679 0.40 ENSDART00000165581
tmsb1
thymosin beta 1
chr12_-_22238004 0.40 ENSDART00000038310
ormdl3
ORMDL sphingolipid biosynthesis regulator 3
chr13_-_30996072 0.39 ENSDART00000181661
wdfy4
WDFY family member 4
chr17_+_43013171 0.39 ENSDART00000055541
gskip
gsk3b interacting protein
chr12_+_17154655 0.36 ENSDART00000028003
ankrd22
ankyrin repeat domain 22
chr6_-_10912424 0.35 ENSDART00000036456
cycsb
cytochrome c, somatic b
chr11_+_23933016 0.35 ENSDART00000000486
cntn2
contactin 2
chr13_-_32898962 0.35 ENSDART00000163757
rock2a
rho-associated, coiled-coil containing protein kinase 2a
chr3_+_15394428 0.34 ENSDART00000133168
atxn2l
ataxin 2-like
chr6_-_10728057 0.34 ENSDART00000002247
sp3b
Sp3b transcription factor
chr15_-_29348212 0.33 ENSDART00000133117
tsku
tsukushi small leucine rich proteoglycan homolog (Xenopus laevis)
chr9_+_2574122 0.33 ENSDART00000166326
ENSDART00000191822
CIR1
si:ch73-167c12.2
chr14_+_16345003 0.31 ENSDART00000003040
ENSDART00000165193
itln3
intelectin 3
chr13_-_25548733 0.30 ENSDART00000168099
ENSDART00000135788
ENSDART00000077655
mcmbp
minichromosome maintenance complex binding protein
chr7_+_38089650 0.29 ENSDART00000052365
cebpg
CCAAT/enhancer binding protein (C/EBP), gamma
chr12_+_34953038 0.29 ENSDART00000187022
ENSDART00000123988
ENSDART00000027034
qki2
QKI, KH domain containing, RNA binding 2
chr3_+_41731527 0.27 ENSDART00000049007
ENSDART00000187866
chst12a
carbohydrate (chondroitin 4) sulfotransferase 12a
chr12_+_36109507 0.27 ENSDART00000175409
map2k6
mitogen-activated protein kinase kinase 6
chr22_+_15973122 0.27 ENSDART00000144545
rc3h1a
ring finger and CCCH-type domains 1a
chr9_-_32300783 0.27 ENSDART00000078596
hspd1
heat shock 60 protein 1
chr6_-_14292307 0.26 ENSDART00000177852
ENSDART00000061745
inpp4ab
inositol polyphosphate-4-phosphatase type I Ab
chr12_-_26383242 0.26 ENSDART00000152941
usp54b
ubiquitin specific peptidase 54b
chr23_-_36003441 0.25 ENSDART00000164699
calcoco1a
calcium binding and coiled-coil domain 1a
chr17_-_10838434 0.25 ENSDART00000064597
lgals3b
lectin, galactoside binding soluble 3b
chr3_+_36972586 0.24 ENSDART00000102784
si:ch211-18i17.2
si:ch211-18i17.2
chr3_+_19216567 0.24 ENSDART00000134433
il12rb2l
interleukin 12 receptor, beta 2a, like
chr23_-_36003282 0.23 ENSDART00000103150
calcoco1a
calcium binding and coiled-coil domain 1a
chr19_-_30810328 0.22 ENSDART00000184875
myclb
MYCL proto-oncogene, bHLH transcription factor b
chr5_-_26893310 0.22 ENSDART00000126669
lman2lb
lectin, mannose-binding 2-like b
chr14_+_7902374 0.22 ENSDART00000113299
zgc:110843
zgc:110843
chr12_+_32368574 0.21 ENSDART00000086389
ANKFN1
si:ch211-277e21.2
chr10_+_44940693 0.21 ENSDART00000157515
cnnm4a
cyclin and CBS domain divalent metal cation transport mediator 4a
chr20_-_19511700 0.20 ENSDART00000040191
snx17
sorting nexin 17
chr21_+_29227224 0.19 ENSDART00000013641
adra1ba
adrenoceptor alpha 1Ba
chr17_+_23975762 0.19 ENSDART00000155941
xpo1b
exportin 1 (CRM1 homolog, yeast) b
chr24_+_9881219 0.18 ENSDART00000036204
cdv3
carnitine deficiency-associated gene expressed in ventricle 3
chr3_+_39663987 0.18 ENSDART00000184614
ENSDART00000184573
ENSDART00000183127
epn2
epsin 2
chr3_-_30153242 0.17 ENSDART00000077089
nucb1
nucleobindin 1
chr9_-_32300611 0.16 ENSDART00000127938
hspd1
heat shock 60 protein 1
chr15_-_24960730 0.16 ENSDART00000109990
ENSDART00000186706
abhd15a
abhydrolase domain containing 15a
chr8_-_37043900 0.16 ENSDART00000139567
renbp
renin binding protein
chr2_+_11029138 0.15 ENSDART00000138737
ENSDART00000081058
ENSDART00000153662
acot11a
acyl-CoA thioesterase 11a
chr7_-_22790630 0.15 ENSDART00000173496
si:ch211-15b10.6
si:ch211-15b10.6
chr24_-_32665283 0.14 ENSDART00000038364
ca2
carbonic anhydrase II
chr3_-_30152836 0.14 ENSDART00000165920
nucb1
nucleobindin 1
chr21_-_14762944 0.14 ENSDART00000114096
arrdc1b
arrestin domain containing 1b
chr5_+_36439405 0.14 ENSDART00000102973
eda
ectodysplasin A
chr25_-_16987020 0.14 ENSDART00000073419
ccnd2a
cyclin D2, a
chr4_+_33012407 0.14 ENSDART00000151873
si:dkey-26h11.2
si:dkey-26h11.2
chr9_-_12034444 0.13 ENSDART00000038651
znf804a
zinc finger protein 804A
chr17_+_5623514 0.12 ENSDART00000171220
ENSDART00000176083
CU571310.1

chr15_+_21882419 0.12 ENSDART00000157216
si:dkey-103g5.4
si:dkey-103g5.4
chr11_-_29082175 0.12 ENSDART00000123245
igsf21a
immunoglobin superfamily, member 21a
chr3_+_36972298 0.11 ENSDART00000150917
si:ch211-18i17.2
si:ch211-18i17.2
chr7_-_39751540 0.11 ENSDART00000016803
grpel1
GrpE-like 1, mitochondrial
chr25_+_3294150 0.10 ENSDART00000030683
tmpob
thymopoietin b
chr8_-_36412936 0.09 ENSDART00000159276
si:zfos-2070c2.3
si:zfos-2070c2.3
chr7_-_7904683 0.09 ENSDART00000192822
CABZ01030278.1

chr10_+_9595575 0.09 ENSDART00000091780
ENSDART00000184287
rc3h2
ring finger and CCCH-type domains 2
chr2_-_49860723 0.09 ENSDART00000083690
blvra
biliverdin reductase A
chr3_-_43821191 0.09 ENSDART00000186816
snn
stannin
chr22_+_31244728 0.08 ENSDART00000163309
grip2b
glutamate receptor interacting protein 2b
chr2_-_36819624 0.07 ENSDART00000140844
slitrk3b
SLIT and NTRK-like family, member 3b
chr3_+_39664256 0.06 ENSDART00000153866
epn2
epsin 2
chr14_-_30945515 0.06 ENSDART00000161540
si:zfos-80g12.1
si:zfos-80g12.1
chr14_-_12071447 0.06 ENSDART00000166116
tmsb1
thymosin beta 1
chr9_-_30808073 0.05 ENSDART00000146300
klf5b
Kruppel-like factor 5b
chr24_-_36727922 0.05 ENSDART00000135142
si:ch73-334d15.1
si:ch73-334d15.1
chr5_+_3501859 0.05 ENSDART00000080486
ywhag1
3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 1
chr5_-_25582721 0.05 ENSDART00000123986
anxa1a
annexin A1a
chr12_-_19862912 0.04 ENSDART00000145788
shisa9a
shisa family member 9a
chr5_+_32162684 0.04 ENSDART00000134472
taok3b
TAO kinase 3b
chr5_-_25583125 0.03 ENSDART00000031665
ENSDART00000145353
anxa1a
annexin A1a
chr21_-_43949208 0.03 ENSDART00000150983
camk2a
calcium/calmodulin-dependent protein kinase II alpha
chr9_-_6927587 0.03 ENSDART00000059092
tmem182a
transmembrane protein 182a
chr9_+_9502610 0.03 ENSDART00000061525
ENSDART00000125174
nr1i2
nuclear receptor subfamily 1, group I, member 2
chr10_-_29733194 0.03 ENSDART00000149252
si:ch73-261i21.2
si:ch73-261i21.2
chr8_-_31716302 0.02 ENSDART00000061832
si:dkey-46a10.3
si:dkey-46a10.3
chr23_+_11285662 0.02 ENSDART00000111028
chl1a
cell adhesion molecule L1-like a
chr4_-_17391091 0.02 ENSDART00000056002
th2
tyrosine hydroxylase 2
chr7_+_15736230 0.02 ENSDART00000109942
mctp2b
multiple C2 domains, transmembrane 2b
chr21_+_1647990 0.02 ENSDART00000148540
fech
ferrochelatase
chr16_+_44298902 0.01 ENSDART00000114795
dpys
dihydropyrimidinase
chr22_+_15336752 0.01 ENSDART00000139070
sult3st2
sulfotransferase family 3, cytosolic sulfotransferase 2
chr5_-_58840971 0.01 ENSDART00000050932
tmem136b
transmembrane protein 136b
chr12_+_35119762 0.01 ENSDART00000085774
si:ch73-127m5.1
si:ch73-127m5.1
chr21_-_40174647 0.00 ENSDART00000183738
ENSDART00000076840
ENSDART00000145109
slco2b1
solute carrier organic anion transporter family, member 2B1
chr15_+_20543770 0.00 ENSDART00000092357
sgsm2
small G protein signaling modulator 2
chr7_+_23580082 0.00 ENSDART00000183245
si:dkey-172j4.3
si:dkey-172j4.3

Network of associatons between targets according to the STRING database.

First level regulatory network of cebpd

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.4 GO:0098967 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.3 1.1 GO:0006531 aspartate metabolic process(GO:0006531)
0.3 0.8 GO:0015882 L-ascorbic acid transport(GO:0015882)
0.2 0.7 GO:0050666 regulation of sulfur amino acid metabolic process(GO:0031335) regulation of homocysteine metabolic process(GO:0050666)
0.2 1.6 GO:1901031 response to leucine(GO:0043201) cellular response to leucine(GO:0071233) regulation of response to reactive oxygen species(GO:1901031)
0.2 1.5 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.2 1.2 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.1 0.7 GO:0010586 miRNA metabolic process(GO:0010586)
0.1 0.3 GO:0048677 axon extension involved in regeneration(GO:0048677) sprouting of injured axon(GO:0048682)
0.1 0.5 GO:0070987 error-free translesion synthesis(GO:0070987)
0.1 0.3 GO:0044333 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333) mediolateral intercalation(GO:0060031)
0.1 1.0 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.1 0.4 GO:0045041 positive regulation of interleukin-6 production(GO:0032755) protein import into mitochondrial intermembrane space(GO:0045041)
0.1 0.4 GO:1900060 regulation of sphingolipid biosynthetic process(GO:0090153) negative regulation of sphingolipid biosynthetic process(GO:0090155) negative regulation of ceramide biosynthetic process(GO:1900060) regulation of membrane lipid metabolic process(GO:1905038) regulation of ceramide biosynthetic process(GO:2000303)
0.1 0.5 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.1 0.6 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.1 1.4 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.1 0.6 GO:0034389 lipid particle organization(GO:0034389)
0.1 0.6 GO:0006741 NADP biosynthetic process(GO:0006741)
0.1 0.3 GO:0003418 chondrocyte differentiation involved in endochondral bone morphogenesis(GO:0003413) growth plate cartilage chondrocyte differentiation(GO:0003418)
0.1 0.4 GO:0000012 single strand break repair(GO:0000012)
0.1 0.6 GO:0032185 septin ring organization(GO:0031106) septin cytoskeleton organization(GO:0032185)
0.1 3.8 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.1 1.0 GO:0016926 protein desumoylation(GO:0016926)
0.1 0.3 GO:0010603 regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.1 0.3 GO:0048245 eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.0 0.4 GO:0006857 oligopeptide transport(GO:0006857)
0.0 0.6 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 0.6 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.0 0.7 GO:0051788 response to misfolded protein(GO:0051788) cellular response to misfolded protein(GO:0071218)
0.0 0.5 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.1 GO:0015670 carbon dioxide transport(GO:0015670)
0.0 0.3 GO:0042989 sequestering of actin monomers(GO:0042989)
0.0 1.0 GO:0032474 otolith morphogenesis(GO:0032474)
0.0 0.6 GO:1901888 regulation of cell junction assembly(GO:1901888)
0.0 0.2 GO:0001996 positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996) positive regulation of blood pressure by epinephrine-norepinephrine(GO:0003321) positive regulation of heart rate(GO:0010460)
0.0 0.2 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.0 0.5 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.2 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.0 0.7 GO:0071875 adrenergic receptor signaling pathway(GO:0071875)
0.0 1.8 GO:0008360 regulation of cell shape(GO:0008360)
0.0 0.6 GO:0006749 glutathione metabolic process(GO:0006749)
0.0 0.3 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.0 0.1 GO:0042167 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.0 1.3 GO:0090630 activation of GTPase activity(GO:0090630)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.9 GO:0097134 cyclin E1-CDK2 complex(GO:0097134)
0.7 2.1 GO:0030289 protein phosphatase 4 complex(GO:0030289)
0.2 1.6 GO:0061700 GATOR2 complex(GO:0061700)
0.1 0.4 GO:0035339 SPOTS complex(GO:0035339)
0.1 0.6 GO:0005826 actomyosin contractile ring(GO:0005826)
0.1 1.4 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.1 0.5 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.1 0.5 GO:0071797 LUBAC complex(GO:0071797)
0.0 0.6 GO:0071007 U2-type catalytic step 2 spliceosome(GO:0071007)
0.0 0.3 GO:0001772 immunological synapse(GO:0001772)
0.0 0.1 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.0 0.7 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.2 GO:0030669 clathrin coat of endocytic vesicle(GO:0030128) clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0 0.3 GO:0042555 MCM complex(GO:0042555)
0.0 0.4 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.6 GO:0005811 lipid particle(GO:0005811)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.5 GO:0004361 glutaryl-CoA dehydrogenase activity(GO:0004361)
0.3 1.1 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069)
0.2 1.6 GO:0070728 leucine binding(GO:0070728)
0.2 0.7 GO:0072591 N-acetyl-L-aspartate-L-glutamate ligase activity(GO:0072590) citrate-L-glutamate ligase activity(GO:0072591)
0.2 0.9 GO:0004908 interleukin-1 receptor activity(GO:0004908)
0.2 1.2 GO:0016880 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.1 0.7 GO:0004122 cystathionine beta-synthase activity(GO:0004122)
0.1 1.0 GO:0072518 Rho-dependent protein serine/threonine kinase activity(GO:0072518)
0.1 1.4 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.1 1.8 GO:0003785 actin monomer binding(GO:0003785)
0.1 0.7 GO:0035198 miRNA binding(GO:0035198)
0.1 1.1 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1 1.0 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.1 3.8 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.1 0.4 GO:0035613 RNA stem-loop binding(GO:0035613)
0.1 0.3 GO:0019865 IgE binding(GO:0019863) immunoglobulin binding(GO:0019865)
0.0 0.7 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.5 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.3 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316)
0.0 0.6 GO:0019211 phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542)
0.0 0.1 GO:1990756 protein binding, bridging involved in substrate recognition for ubiquitination(GO:1990756)
0.0 0.7 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.2 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.0 2.1 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 0.2 GO:0034338 short-chain carboxylesterase activity(GO:0034338)
0.0 0.2 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.0 0.6 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 1.4 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.2 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.6 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.2 GO:0005537 mannose binding(GO:0005537)
0.0 0.8 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.6 GO:0016307 phosphatidylinositol phosphate kinase activity(GO:0016307)
0.0 0.6 GO:0003951 NAD+ kinase activity(GO:0003951)
0.0 0.3 GO:0070492 oligosaccharide binding(GO:0070492)
0.0 0.5 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.8 GO:0009055 electron carrier activity(GO:0009055)
0.0 0.1 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 0.3 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.7 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.4 GO:0051018 protein kinase A binding(GO:0051018)
0.0 0.1 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.2 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.4 GO:0003684 damaged DNA binding(GO:0003684)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.9 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 1.4 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.3 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 1.0 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.8 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.4 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.5 PID AR TF PATHWAY Regulation of Androgen receptor activity

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.9 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.1 0.7 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.1 0.7 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.1 0.8 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.6 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.7 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.3 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.4 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 0.5 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.0 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII