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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for clocka+clockb+npas2

Z-value: 2.72

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Transcription factors associated with clocka+clockb+npas2

Gene Symbol Gene ID Gene Info
clockb
ENSDARG00000003631 clock circadian regulator b
clocka
ENSDARG00000011703 clock circadian regulator a
npas2
ENSDARG00000016536 neuronal PAS domain protein 2
npas2
ENSDARG00000116993 neuronal PAS domain protein 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
clockadr11_v1_chr20_+_22130284_22130284-0.475.1e-02Click!
npas2dr11_v1_chr5_+_22791686_227916860.381.2e-01Click!
clockbdr11_v1_chr1_+_19433004_194330040.155.5e-01Click!

Activity profile of clocka+clockb+npas2 motif

Sorted Z-values of clocka+clockb+npas2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr18_+_184746 8.87 ENSDART00000140897
larp6a
La ribonucleoprotein domain family, member 6a
chr16_-_34195002 8.70 ENSDART00000054026
rcc1
regulator of chromosome condensation 1
chr12_+_13091842 6.93 ENSDART00000185477
ENSDART00000181435
ENSDART00000124799
si:ch211-103b1.2
si:ch211-103b1.2
chr12_-_33359654 5.75 ENSDART00000001907
slc16a3
solute carrier family 16 (monocarboxylate transporter), member 3
chr3_-_3398383 5.71 ENSDART00000047865
si:dkey-46g23.2
si:dkey-46g23.2
chr15_-_17099560 5.32 ENSDART00000101724
mos
v-mos Moloney murine sarcoma viral oncogene homolog
chr14_+_22076596 4.94 ENSDART00000106147
ENSDART00000100278
ENSDART00000131489
slc43a1a
solute carrier family 43 (amino acid system L transporter), member 1a
chr24_+_36317544 4.86 ENSDART00000048640
ENSDART00000156096
pus3
pseudouridylate synthase 3
chr14_-_49992709 4.60 ENSDART00000159988
fam193b
family with sequence similarity 193, member B
chr19_+_20201254 4.56 ENSDART00000010140
igf2bp3
insulin-like growth factor 2 mRNA binding protein 3
chr18_+_8917766 4.52 ENSDART00000145226
si:ch211-233h19.2
si:ch211-233h19.2
chr23_+_25292147 4.36 ENSDART00000131486
pa2g4b
proliferation-associated 2G4, b
chr13_+_39277178 4.32 ENSDART00000113259
si:dkey-85a20.4
si:dkey-85a20.4
chr5_+_69950882 4.25 ENSDART00000097359
dnajc25
DnaJ (Hsp40) homolog, subfamily C , member 25
chr3_+_7763114 4.23 ENSDART00000057434
hook2
hook microtubule-tethering protein 2
chr7_+_41812636 4.11 ENSDART00000174333
orc6
origin recognition complex, subunit 6
chr17_-_51651631 4.08 ENSDART00000154699
ccr6b
chemokine (C-C motif) receptor 6b
chr10_+_22034477 4.06 ENSDART00000133304
ENSDART00000134189
ENSDART00000021240
ENSDART00000100526
npm1a
nucleophosmin 1a
chr22_+_835728 4.01 ENSDART00000003325
dennd2db
DENN/MADD domain containing 2Db
chr9_+_27720428 3.97 ENSDART00000112415
lcmt2
leucine carboxyl methyltransferase 2
chr15_-_2519640 3.90 ENSDART00000047013
srprb
signal recognition particle receptor, B subunit
chr8_+_26059677 3.90 ENSDART00000009178
impdh2
IMP (inosine 5'-monophosphate) dehydrogenase 2
chr7_+_29163762 3.85 ENSDART00000173762
slc38a8b
solute carrier family 38, member 8b
chr6_+_3717613 3.83 ENSDART00000184330
ssb
Sjogren syndrome antigen B (autoantigen La)
chr19_+_20201593 3.81 ENSDART00000163026
igf2bp3
insulin-like growth factor 2 mRNA binding protein 3
chr12_-_33359052 3.79 ENSDART00000135943
slc16a3
solute carrier family 16 (monocarboxylate transporter), member 3
chr11_-_12800945 3.69 ENSDART00000191178
txlng
taxilin gamma
chr11_-_12801157 3.58 ENSDART00000103449
txlng
taxilin gamma
chr14_+_35414632 3.51 ENSDART00000191516
ENSDART00000084914
trmt12
tRNA methyltransferase 12 homolog (S. cerevisiae)
chr7_+_41812817 3.44 ENSDART00000174165
orc6
origin recognition complex, subunit 6
chr16_+_25259313 3.42 ENSDART00000058938
fbxo32
F-box protein 32
chr2_+_205763 3.41 ENSDART00000160164
ENSDART00000101071
zgc:113293
zgc:113293
chr10_+_39283985 3.40 ENSDART00000016464
dcps
decapping enzyme, scavenger
chr22_-_17653143 3.37 ENSDART00000089171
hmha1b
histocompatibility (minor) HA-1 b
chr8_-_38317914 3.32 ENSDART00000125920
pdlim2
PDZ and LIM domain 2 (mystique)
chr11_-_44194132 3.31 ENSDART00000182954
ENSDART00000111271
CABZ01080074.1

chr7_+_41812190 3.28 ENSDART00000113732
ENSDART00000174137
orc6
origin recognition complex, subunit 6
chr25_-_14424406 3.28 ENSDART00000073609
prmt7
protein arginine methyltransferase 7
chr22_-_20695237 3.27 ENSDART00000112722
org
oogenesis-related gene
chr19_-_11015238 3.21 ENSDART00000010997
tpm3
tropomyosin 3
chr20_+_2642855 3.18 ENSDART00000058775
zgc:101562
zgc:101562
chr1_+_494297 3.14 ENSDART00000108579
ENSDART00000146732
blzf1
basic leucine zipper nuclear factor 1
chr5_-_32505276 3.10 ENSDART00000034705
ENSDART00000187597
ntmt1
N-terminal Xaa-Pro-Lys N-methyltransferase 1
chr2_+_25840463 3.10 ENSDART00000125178
eif5a2
eukaryotic translation initiation factor 5A2
chr16_+_35535375 3.10 ENSDART00000171675
cited4b
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4b
chr2_+_25839940 3.05 ENSDART00000139927
eif5a2
eukaryotic translation initiation factor 5A2
chr2_+_25839650 3.03 ENSDART00000134077
ENSDART00000140804
eif5a2
eukaryotic translation initiation factor 5A2
chr1_+_49814942 3.02 ENSDART00000164936
lef1
lymphoid enhancer-binding factor 1
chr8_-_18203274 3.01 ENSDART00000134078
ENSDART00000180235
ENSDART00000080006
ENSDART00000125418
ENSDART00000142114
elovl8b
ELOVL fatty acid elongase 8b
chr2_-_49860723 3.00 ENSDART00000083690
blvra
biliverdin reductase A
chr23_+_25291891 2.97 ENSDART00000016248
pa2g4b
proliferation-associated 2G4, b
chr1_+_6135176 2.95 ENSDART00000092324
ENSDART00000179970
abcb6a
ATP-binding cassette, sub-family B (MDR/TAP), member 6a
chr5_+_24543862 2.94 ENSDART00000029699
atp6v0a2b
ATPase H+ transporting V0 subunit a2b
chr17_-_49407091 2.90 ENSDART00000021950
mthfd1b
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1b
chr5_-_32505109 2.89 ENSDART00000188219
ntmt1
N-terminal Xaa-Pro-Lys N-methyltransferase 1
chr10_-_14943281 2.85 ENSDART00000143608
smad2
SMAD family member 2
chr13_+_8892784 2.85 ENSDART00000075054
ENSDART00000143705
thada
thyroid adenoma associated
chr10_-_7821686 2.83 ENSDART00000121531
mat2aa
methionine adenosyltransferase II, alpha a
chr9_-_27391908 2.81 ENSDART00000135221
nepro
nucleolus and neural progenitor protein
chr3_+_31662126 2.81 ENSDART00000113441
mylk5
myosin, light chain kinase 5
chr24_+_34069675 2.80 ENSDART00000143995
si:ch211-190p8.2
si:ch211-190p8.2
chr3_-_58165254 2.76 ENSDART00000093031
snu13a
SNU13 homolog, small nuclear ribonucleoprotein a (U4/U6.U5)
chr1_-_26676391 2.76 ENSDART00000152492
trmo
tRNA methyltransferase O
chr9_+_21358941 2.75 ENSDART00000147619
ENSDART00000059402
eef1akmt1
EEF1A lysine methyltransferase 1
chr7_+_70338270 2.73 ENSDART00000065234
gba3
glucosidase, beta, acid 3 (gene/pseudogene)
chr5_-_24543526 2.72 ENSDART00000046384
trmt2a
tRNA methyltransferase 2 homolog A
chr24_-_38644937 2.71 ENSDART00000170194
slc6a16b
solute carrier family 6, member 16b
chr1_-_26675969 2.70 ENSDART00000054184
trmo
tRNA methyltransferase O
chr19_-_81851 2.70 ENSDART00000172319
hnrnpr
heterogeneous nuclear ribonucleoprotein R
chr12_-_1034383 2.69 ENSDART00000152455
ENSDART00000152346
polr3e
polymerase (RNA) III (DNA directed) polypeptide E
chr7_+_30779761 2.69 ENSDART00000066806
ENSDART00000173671
mcee
methylmalonyl CoA epimerase
chr4_+_4849789 2.64 ENSDART00000130818
ENSDART00000127751
ptprz1b
protein tyrosine phosphatase, receptor-type, Z polypeptide 1b
chr7_-_29164818 2.62 ENSDART00000052348
exosc6
exosome component 6
chr23_-_10786400 2.54 ENSDART00000055038
rybpa
RING1 and YY1 binding protein a
chr3_+_27770110 2.53 ENSDART00000017962
eci1
enoyl-CoA delta isomerase 1
chr2_-_32594777 2.53 ENSDART00000134125
fastk
Fas-activated serine/threonine kinase
chr5_+_37744625 2.52 ENSDART00000014031
dpf2
D4, zinc and double PHD fingers family 2
chr8_-_18203092 2.51 ENSDART00000140620
elovl8b
ELOVL fatty acid elongase 8b
chr19_-_47832853 2.51 ENSDART00000170988
ago4
argonaute RISC catalytic component 4
chr22_-_19102256 2.50 ENSDART00000171866
ENSDART00000166295
polrmt
polymerase (RNA) mitochondrial (DNA directed)
chr15_+_44250335 2.50 ENSDART00000186162
ENSDART00000193503
ENSDART00000180275
zgc:162962
zgc:162962
chr1_+_494873 2.49 ENSDART00000134581
blzf1
basic leucine zipper nuclear factor 1
chr20_-_38827623 2.48 ENSDART00000153310
cad
carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
chr5_+_36654817 2.48 ENSDART00000131339
capns1a
calpain, small subunit 1 a
chr19_-_31035325 2.46 ENSDART00000147504
bzw2
basic leucine zipper and W2 domains 2
chr3_-_25377163 2.45 ENSDART00000055490
kpna2
karyopherin alpha 2 (RAG cohort 1, importin alpha 1)
chr20_+_36806398 2.45 ENSDART00000153317
abracl
ABRA C-terminal like
chr5_+_65040228 2.45 ENSDART00000164278
pmpca
peptidase (mitochondrial processing) alpha
chr4_+_17642731 2.43 ENSDART00000026509
cwf19l1
CWF19-like 1, cell cycle control
chr22_-_36690742 2.41 ENSDART00000017188
ENSDART00000124698
ncl
nucleolin
chr21_+_34119759 2.39 ENSDART00000024750
ENSDART00000128242
hmgb3b
high mobility group box 3b
chr23_-_14403939 2.38 ENSDART00000090930
nkain4
sodium/potassium transporting ATPase interacting 4
chr10_+_29770120 2.36 ENSDART00000100032
ENSDART00000193205
hyou1
hypoxia up-regulated 1
chr22_-_11054244 2.35 ENSDART00000105823
insrb
insulin receptor b
chr24_-_20016817 2.35 ENSDART00000082201
ENSDART00000189448
slc22a13b
solute carrier family 22 member 13b
chr13_+_6189203 2.35 ENSDART00000109665
ppm1g
protein phosphatase, Mg2+/Mn2+ dependent, 1G
chr19_-_31035155 2.34 ENSDART00000161882
bzw2
basic leucine zipper and W2 domains 2
chr9_+_24065855 2.32 ENSDART00000161468
ENSDART00000171577
ENSDART00000172743
ENSDART00000159324
ENSDART00000079689
ENSDART00000023196
ENSDART00000101577
lrrfip1a
leucine rich repeat (in FLII) interacting protein 1a
chr19_-_81477 2.32 ENSDART00000159815
hnrnpr
heterogeneous nuclear ribonucleoprotein R
chr7_-_41812015 2.30 ENSDART00000174058
vps35
vacuolar protein sorting 35 homolog (S. cerevisiae)
chr6_-_59357256 2.28 ENSDART00000074534
fam210b
family with sequence similarity 210, member B
chr13_+_6188759 2.26 ENSDART00000161062
ppm1g
protein phosphatase, Mg2+/Mn2+ dependent, 1G
chr25_+_21098675 2.25 ENSDART00000079012
rad52
RAD52 homolog, DNA repair protein
chr2_+_37815687 2.25 ENSDART00000166352
sdr39u1
short chain dehydrogenase/reductase family 39U, member 1
chr20_-_4793450 2.24 ENSDART00000053870
galca
galactosylceramidase a
chr25_+_22572296 2.22 ENSDART00000152096
stra6
stimulated by retinoic acid 6
chr7_+_66048102 2.22 ENSDART00000104523
arntl1b
aryl hydrocarbon receptor nuclear translocator-like 1b
chr10_-_39283883 2.19 ENSDART00000023831
cry5
cryptochrome circadian clock 5
chr25_-_35101673 2.18 ENSDART00000140864
zgc:162611
zgc:162611
chr9_-_11587070 2.18 ENSDART00000030995
umps
uridine monophosphate synthetase
chr25_+_8921425 2.16 ENSDART00000128591
accs
1-aminocyclopropane-1-carboxylate synthase homolog (Arabidopsis)(non-functional)
chr12_-_28349026 2.15 ENSDART00000183768
ENSDART00000152998
zgc:195081
zgc:195081
chr1_-_19648227 2.14 ENSDART00000054574
polr1e
polymerase (RNA) I polypeptide E
chr3_-_1339220 2.14 ENSDART00000172000
tmem106c
transmembrane protein 106C
chr10_+_8437930 2.14 ENSDART00000074553
pptc7b
PTC7 protein phosphatase homolog b
chr18_+_38191346 2.10 ENSDART00000052703
nucb2b
nucleobindin 2b
chr3_-_34586403 2.09 ENSDART00000151515
sept9a
septin 9a
chr25_-_35101396 2.09 ENSDART00000138865
zgc:162611
zgc:162611
chr2_+_6885852 2.09 ENSDART00000016607
rgs5b
regulator of G protein signaling 5b
chr13_+_35925490 2.08 ENSDART00000046115
mfsd2aa
major facilitator superfamily domain containing 2aa
chr20_-_14941046 2.07 ENSDART00000152775
ENSDART00000152516
ENSDART00000021394
mettl13
methyltransferase like 13
chr21_+_1586379 2.04 ENSDART00000150961
wdr91
WD repeat domain 91
chr5_+_29715040 2.02 ENSDART00000192563
ddx31
DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
chr4_-_16824231 2.01 ENSDART00000014007
gys2
glycogen synthase 2
chr21_-_44081540 2.00 ENSDART00000130833
FO704810.1

chr21_+_43702016 1.98 ENSDART00000017176
dkc1
dyskeratosis congenita 1, dyskerin
chr11_-_24538852 1.98 ENSDART00000171004
ENSDART00000181039
plekhg5a
pleckstrin homology domain containing, family G (with RhoGef domain) member 5a
chr13_-_24260609 1.97 ENSDART00000138747
urb2
URB2 ribosome biogenesis 2 homolog (S. cerevisiae)
chr18_+_6126506 1.96 ENSDART00000125725
si:ch1073-390k14.1
si:ch1073-390k14.1
chr4_-_16824556 1.94 ENSDART00000165289
ENSDART00000185839
gys2
glycogen synthase 2
chr7_+_32021982 1.93 ENSDART00000173848
mettl15
methyltransferase like 15
chr12_-_34827477 1.92 ENSDART00000153026
NDUFAF8
si:dkey-21c1.6
chr12_+_45150709 1.92 ENSDART00000112750
dhx32a
DEAH (Asp-Glu-Ala-His) box polypeptide 32a
chr6_-_1187565 1.92 ENSDART00000191756
txnrd3
thioredoxin reductase 3
chr6_+_38626926 1.90 ENSDART00000190339
atp10a
ATPase phospholipid transporting 10A
chr11_-_2297832 1.89 ENSDART00000158266
znf740a
zinc finger protein 740a
chr11_-_16975190 1.89 ENSDART00000122222
suclg2
succinate-CoA ligase, GDP-forming, beta subunit
chr22_+_438714 1.89 ENSDART00000136491
celsr2
cadherin, EGF LAG seven-pass G-type receptor 2
chr1_-_29061285 1.88 ENSDART00000053933
ENSDART00000142350
ENSDART00000192615
gemin8
gem (nuclear organelle) associated protein 8
chr3_-_43662495 1.88 ENSDART00000166729
axin1
axin 1
chr24_-_42090635 1.87 ENSDART00000166413
ssr1
signal sequence receptor, alpha
chr25_-_13871118 1.86 ENSDART00000160866
cry2
cryptochrome circadian clock 2
chr1_-_157563 1.86 ENSDART00000018741
pcid2
PCI domain containing 2
chr7_-_41726657 1.85 ENSDART00000099121
arl8
ADP-ribosylation factor-like 8
chr23_+_26017227 1.85 ENSDART00000002939
pfkfb1
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr12_+_48390715 1.84 ENSDART00000149351
scd
stearoyl-CoA desaturase (delta-9-desaturase)
chr19_+_2685779 1.84 ENSDART00000160533
ENSDART00000097531
tomm7
translocase of outer mitochondrial membrane 7 homolog (yeast)
chr7_+_32021669 1.81 ENSDART00000173976
mettl15
methyltransferase like 15
chr9_+_19623363 1.81 ENSDART00000142471
ENSDART00000147662
ENSDART00000136053
pdxka
pyridoxal (pyridoxine, vitamin B6) kinase a
chr16_+_50741154 1.79 ENSDART00000101627
IGLON5
zgc:110372
chr12_-_9516981 1.78 ENSDART00000106285
si:ch211-207i20.3
si:ch211-207i20.3
chr4_-_1839192 1.78 ENSDART00000003790
pwp1
PWP1 homolog (S. cerevisiae)
chr9_-_27719998 1.77 ENSDART00000161068
ENSDART00000148195
ENSDART00000138386
gtf2e1
general transcription factor IIE, polypeptide 1, alpha
chr15_+_20239141 1.77 ENSDART00000101152
ENSDART00000152473
spint2
serine peptidase inhibitor, Kunitz type, 2
chr5_-_33959868 1.76 ENSDART00000143652
zgc:63972
zgc:63972
chr19_-_25119443 1.76 ENSDART00000148953
ptp4a3
protein tyrosine phosphatase type IVA, member 3
chr6_-_40651944 1.76 ENSDART00000187423
ppil1
peptidylprolyl isomerase (cyclophilin)-like 1
chr21_-_22122312 1.75 ENSDART00000101726
slc35f2
solute carrier family 35, member F2
chr8_-_22288258 1.75 ENSDART00000140978
ENSDART00000100046
si:ch211-147a11.3
si:ch211-147a11.3
chr17_-_29249258 1.75 ENSDART00000031458
traf3
TNF receptor-associated factor 3
chr8_+_26868105 1.74 ENSDART00000005337
rimkla
ribosomal modification protein rimK-like family member A
chr23_-_43595956 1.74 ENSDART00000162186
itchb
itchy E3 ubiquitin protein ligase b
chr8_-_22288004 1.73 ENSDART00000100042
si:ch211-147a11.3
si:ch211-147a11.3
chr6_-_39919982 1.73 ENSDART00000065091
ENSDART00000064903
sumf1
sulfatase modifying factor 1
chr20_+_26987416 1.73 ENSDART00000012816
sel1l
sel-1 suppressor of lin-12-like (C. elegans)
chr9_+_24920677 1.72 ENSDART00000037025
slc39a10
solute carrier family 39 (zinc transporter), member 10
chr1_+_5485799 1.72 ENSDART00000022307
atic
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
chr4_-_27897160 1.72 ENSDART00000066924
ENSDART00000066925
ENSDART00000193020
tbc1d22a
TBC1 domain family, member 22a
chr21_+_31150773 1.72 ENSDART00000126205
st6gal1
ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
chr2_-_40890004 1.72 ENSDART00000191746
uggt1
UDP-glucose glycoprotein glucosyltransferase 1
chr15_+_784149 1.70 ENSDART00000155114
znf970
zinc finger protein 970
chr16_-_38333976 1.69 ENSDART00000031895
cdc42se1
CDC42 small effector 1
chr24_-_17400472 1.69 ENSDART00000024691
cul1b
cullin 1b
chr2_-_40890264 1.68 ENSDART00000123886
uggt1
UDP-glucose glycoprotein glucosyltransferase 1
chr12_-_27588299 1.67 ENSDART00000178023
ENSDART00000066282
dhx8
DEAH (Asp-Glu-Ala-His) box polypeptide 8
chr25_-_30344117 1.67 ENSDART00000167077
pdia3
protein disulfide isomerase family A, member 3
chr20_-_28433616 1.67 ENSDART00000169289
wdr21
WD repeat domain 21
chr5_+_29714786 1.65 ENSDART00000148314
ddx31
DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
chr25_-_6292560 1.64 ENSDART00000153496
wdr61
WD repeat domain 61
chr7_+_16033273 1.64 ENSDART00000187303
immp1l
inner mitochondrial membrane peptidase subunit 1
chr2_-_37803614 1.64 ENSDART00000154124
nfatc4
nuclear factor of activated T cells 4
chr7_-_41812355 1.63 ENSDART00000016105
vps35
vacuolar protein sorting 35 homolog (S. cerevisiae)
chr5_-_37959874 1.63 ENSDART00000031719
mpzl2b
myelin protein zero-like 2b
chr12_+_47081783 1.63 ENSDART00000158568
mtr
5-methyltetrahydrofolate-homocysteine methyltransferase
chr22_+_1440702 1.62 ENSDART00000165677
si:dkeyp-53d3.3
si:dkeyp-53d3.3
chr12_-_21684197 1.62 ENSDART00000152999
ENSDART00000153109
ENSDART00000148698
eme1
essential meiotic structure-specific endonuclease 1
chr3_+_15893039 1.61 ENSDART00000055780
jpt2
Jupiter microtubule associated homolog 2
chr12_-_17492852 1.60 ENSDART00000012421
ENSDART00000138766
ENSDART00000130735
minpp1b
multiple inositol-polyphosphate phosphatase 1b
chr5_+_27488975 1.59 ENSDART00000123635
sfrp1a
secreted frizzled-related protein 1a
chr7_+_29167744 1.58 ENSDART00000076345
slc38a8b
solute carrier family 38, member 8b
chr10_-_105100 1.57 ENSDART00000145716
ttc3
tetratricopeptide repeat domain 3
chr19_+_42328423 1.57 ENSDART00000077059
anp32e
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr15_-_5720583 1.56 ENSDART00000158034
ENSDART00000190332
ENSDART00000109599
urb1
URB1 ribosome biogenesis 1 homolog (S. cerevisiae)
chr16_+_23891443 1.56 ENSDART00000058970
gtpbp10
GTP-binding protein 10 (putative)
chr5_-_30145939 1.56 ENSDART00000086795
zbtb44
zinc finger and BTB domain containing 44
chr13_-_25199260 1.55 ENSDART00000057605
adka
adenosine kinase a
chr6_+_3343834 1.54 ENSDART00000160290
st3gal3a
ST3 beta-galactoside alpha-2,3-sialyltransferase 3a
chr10_-_15854743 1.54 ENSDART00000092343
tjp2a
tight junction protein 2a (zona occludens 2)
chr16_-_35427060 1.53 ENSDART00000172294
ctps1b
CTP synthase 1b
chr4_+_25607743 1.53 ENSDART00000028297
acot14
acyl-CoA thioesterase 14

Network of associatons between targets according to the STRING database.

First level regulatory network of clocka+clockb+npas2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 6.0 GO:0006480 N-terminal protein amino acid methylation(GO:0006480)
1.8 5.3 GO:1905133 meiotic cell cycle phase transition(GO:0044771) metaphase/anaphase transition of meiotic cell cycle(GO:0044785) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994) regulation of metaphase/anaphase transition of meiotic cell cycle(GO:1902102) negative regulation of metaphase/anaphase transition of meiotic cell cycle(GO:1902103) regulation of meiotic chromosome separation(GO:1905132) negative regulation of meiotic chromosome separation(GO:1905133)
1.5 10.3 GO:0045905 positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
1.4 6.8 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
1.3 4.0 GO:0031591 wybutosine metabolic process(GO:0031590) wybutosine biosynthetic process(GO:0031591)
1.2 8.7 GO:1901673 regulation of mitotic spindle assembly(GO:1901673)
1.2 3.5 GO:0045002 double-strand break repair via single-strand annealing(GO:0045002)
1.1 3.3 GO:0071514 genetic imprinting(GO:0071514)
1.0 3.1 GO:0001112 DNA-templated transcriptional open complex formation(GO:0001112) transcriptional open complex formation at RNA polymerase II promoter(GO:0001113) protein-DNA complex remodeling(GO:0001120)
0.9 4.7 GO:0044205 'de novo' UMP biosynthetic process(GO:0044205)
0.7 2.2 GO:0051096 regulation of helicase activity(GO:0051095) positive regulation of helicase activity(GO:0051096)
0.7 6.9 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.6 5.0 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.6 1.9 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.6 3.0 GO:0060784 regulation of cell proliferation involved in tissue homeostasis(GO:0060784)
0.6 1.8 GO:0042822 pyridoxal phosphate metabolic process(GO:0042822) pyridoxal phosphate biosynthetic process(GO:0042823)
0.6 2.9 GO:0061072 iris morphogenesis(GO:0061072)
0.6 4.1 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.6 1.7 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.6 1.7 GO:0000390 spliceosomal complex disassembly(GO:0000390)
0.5 7.1 GO:0009303 rRNA transcription(GO:0009303)
0.5 2.1 GO:0035633 maintenance of blood-brain barrier(GO:0035633)
0.5 1.6 GO:0090069 regulation of ribosome biogenesis(GO:0090069)
0.5 3.4 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.5 1.9 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.5 2.9 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.5 1.9 GO:0090244 Wnt signaling pathway involved in somitogenesis(GO:0090244)
0.5 1.8 GO:1903292 protein localization to Golgi membrane(GO:1903292)
0.5 1.8 GO:1903966 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.4 2.2 GO:0071938 vitamin A transport(GO:0071938) vitamin A import(GO:0071939)
0.4 2.6 GO:0071051 polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.4 3.7 GO:0070475 rRNA base methylation(GO:0070475)
0.4 2.8 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.4 3.8 GO:0046037 GMP biosynthetic process(GO:0006177) GMP metabolic process(GO:0046037)
0.4 3.4 GO:0046716 muscle cell cellular homeostasis(GO:0046716)
0.4 1.1 GO:0060912 cardiac cell fate specification(GO:0060912)
0.3 2.0 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.3 1.0 GO:0035973 aggrephagy(GO:0035973)
0.3 1.0 GO:0061355 Wnt protein secretion(GO:0061355)
0.3 2.5 GO:0033015 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.3 2.5 GO:0044528 regulation of mitochondrial mRNA stability(GO:0044528)
0.3 2.5 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.3 0.6 GO:0070086 ubiquitin-dependent endocytosis(GO:0070086)
0.3 10.2 GO:0030488 tRNA methylation(GO:0030488)
0.3 0.9 GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.3 6.3 GO:0034626 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.3 2.7 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.3 1.2 GO:0006526 arginine biosynthetic process(GO:0006526)
0.3 4.7 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.3 1.2 GO:0010259 multicellular organism aging(GO:0010259)
0.3 0.8 GO:0042416 dopamine biosynthetic process from tyrosine(GO:0006585) dopamine biosynthetic process(GO:0042416)
0.3 0.8 GO:0035971 peptidyl-histidine dephosphorylation(GO:0035971)
0.3 0.5 GO:0045117 azole transport(GO:0045117)
0.3 1.1 GO:0045041 protein import into mitochondrial intermembrane space(GO:0045041)
0.3 1.0 GO:0051661 maintenance of centrosome location(GO:0051661)
0.3 1.5 GO:0044209 AMP salvage(GO:0044209)
0.3 1.5 GO:1902946 positive regulation of receptor-mediated endocytosis(GO:0048260) protein localization to early endosome(GO:1902946)
0.3 4.3 GO:0043001 Golgi to plasma membrane protein transport(GO:0043001)
0.3 1.8 GO:0008063 Toll signaling pathway(GO:0008063)
0.2 8.4 GO:0006270 DNA replication initiation(GO:0006270)
0.2 1.5 GO:0006356 regulation of transcription from RNA polymerase I promoter(GO:0006356) positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.2 0.7 GO:0043504 mitochondrial DNA repair(GO:0043504)
0.2 1.4 GO:0032447 tRNA wobble position uridine thiolation(GO:0002143) protein urmylation(GO:0032447)
0.2 1.3 GO:0098957 anterograde axonal transport of mitochondrion(GO:0098957)
0.2 0.9 GO:0070129 regulation of mitochondrial translation(GO:0070129) positive regulation of mitochondrial translation(GO:0070131)
0.2 0.9 GO:0072314 glomerular visceral epithelial cell fate commitment(GO:0072149) glomerular epithelial cell fate commitment(GO:0072314)
0.2 10.8 GO:0030490 maturation of SSU-rRNA(GO:0030490)
0.2 2.9 GO:0045851 vacuolar acidification(GO:0007035) pH reduction(GO:0045851) intracellular pH reduction(GO:0051452)
0.2 0.6 GO:0019408 dolichol biosynthetic process(GO:0019408)
0.2 2.5 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.2 1.0 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.2 1.0 GO:0046952 ketone body catabolic process(GO:0046952)
0.2 0.6 GO:0002188 translation reinitiation(GO:0002188)
0.2 0.4 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.2 2.9 GO:0035999 tetrahydrofolate interconversion(GO:0035999)
0.2 1.5 GO:0070933 histone H4 deacetylation(GO:0070933)
0.2 2.8 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.2 0.7 GO:1903385 dendrite guidance(GO:0070983) regulation of homophilic cell adhesion(GO:1903385)
0.2 2.7 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.2 1.9 GO:0021754 facial nucleus development(GO:0021754)
0.2 4.6 GO:0045454 cell redox homeostasis(GO:0045454)
0.2 0.6 GO:0090387 phagosome maturation involved in apoptotic cell clearance(GO:0090386) phagolysosome assembly involved in apoptotic cell clearance(GO:0090387)
0.2 2.0 GO:0045022 regulation of lipid kinase activity(GO:0043550) regulation of phosphatidylinositol 3-kinase activity(GO:0043551) early endosome to late endosome transport(GO:0045022) vesicle-mediated transport between endosomal compartments(GO:0098927)
0.2 2.5 GO:0045974 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.2 2.8 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.2 1.5 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.2 3.9 GO:0045047 protein targeting to ER(GO:0045047) establishment of protein localization to endoplasmic reticulum(GO:0072599)
0.2 2.1 GO:0032094 response to food(GO:0032094)
0.1 0.4 GO:0042220 response to cocaine(GO:0042220) cellular response to alkaloid(GO:0071312) cellular response to cocaine(GO:0071314)
0.1 0.8 GO:0015864 uridine transport(GO:0015862) pyrimidine nucleoside transport(GO:0015864)
0.1 4.8 GO:0072015 glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310)
0.1 2.4 GO:0051897 positive regulation of protein kinase B signaling(GO:0051897)
0.1 1.0 GO:0070572 positive regulation of axon regeneration(GO:0048680) positive regulation of neuron projection regeneration(GO:0070572)
0.1 0.5 GO:2000660 regulation of interleukin-1-mediated signaling pathway(GO:2000659) negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.1 0.6 GO:0006107 oxaloacetate metabolic process(GO:0006107)
0.1 1.6 GO:0031573 intra-S DNA damage checkpoint(GO:0031573)
0.1 2.7 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.1 1.6 GO:0009086 methionine biosynthetic process(GO:0009086)
0.1 1.8 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.1 0.6 GO:0009052 pentose-phosphate shunt, non-oxidative branch(GO:0009052)
0.1 0.5 GO:0060437 lung growth(GO:0060437) secretion by lung epithelial cell involved in lung growth(GO:0061033)
0.1 0.5 GO:0010874 regulation of cholesterol efflux(GO:0010874)
0.1 1.1 GO:0032024 positive regulation of insulin secretion(GO:0032024)
0.1 3.8 GO:0009648 photoperiodism(GO:0009648)
0.1 1.4 GO:0051156 glucose 6-phosphate metabolic process(GO:0051156)
0.1 0.4 GO:0042754 negative regulation of circadian rhythm(GO:0042754)
0.1 2.4 GO:0071456 cellular response to hypoxia(GO:0071456)
0.1 1.5 GO:0044154 histone H3-K14 acetylation(GO:0044154)
0.1 0.8 GO:1902262 apoptotic process involved in patterning of blood vessels(GO:1902262)
0.1 6.5 GO:0051028 mRNA transport(GO:0051028)
0.1 0.4 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.1 0.3 GO:1902024 L-histidine transmembrane transport(GO:0089709) L-histidine transport(GO:1902024)
0.1 0.5 GO:0097250 mitochondrial respiratory chain supercomplex assembly(GO:0097250)
0.1 3.9 GO:0009250 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.1 2.5 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.1 1.3 GO:0021680 cerebellar Purkinje cell layer development(GO:0021680)
0.1 1.6 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.1 4.0 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.1 0.9 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.1 1.1 GO:0016486 peptide hormone processing(GO:0016486)
0.1 0.3 GO:0060584 regulation of systemic arterial blood pressure by endothelin(GO:0003100) vein smooth muscle contraction(GO:0014826) regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.1 1.6 GO:0043486 histone exchange(GO:0043486)
0.1 1.7 GO:0038061 NIK/NF-kappaB signaling(GO:0038061)
0.1 2.1 GO:0014866 skeletal myofibril assembly(GO:0014866)
0.1 2.5 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.1 9.2 GO:0001756 somitogenesis(GO:0001756)
0.1 0.2 GO:0071635 regulation of natural killer cell activation(GO:0032814) positive regulation of natural killer cell activation(GO:0032816) regulation of transforming growth factor beta production(GO:0071634) negative regulation of transforming growth factor beta production(GO:0071635)
0.1 0.6 GO:0061026 cardiac muscle tissue regeneration(GO:0061026)
0.1 3.7 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.1 1.9 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.1 1.0 GO:0050728 negative regulation of inflammatory response(GO:0050728)
0.1 3.6 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.1 1.9 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.1 2.6 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.1 1.9 GO:0045332 phospholipid translocation(GO:0045332)
0.1 4.9 GO:0048846 axon extension involved in axon guidance(GO:0048846) neuron projection extension involved in neuron projection guidance(GO:1902284)
0.1 1.6 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.1 6.2 GO:0006457 protein folding(GO:0006457)
0.1 0.5 GO:0032228 regulation of synaptic transmission, GABAergic(GO:0032228)
0.1 0.4 GO:0032475 otolith formation(GO:0032475)
0.1 0.9 GO:0006265 DNA topological change(GO:0006265)
0.1 2.0 GO:1902036 regulation of hematopoietic stem cell differentiation(GO:1902036)
0.1 1.5 GO:0048920 posterior lateral line neuromast primordium migration(GO:0048920)
0.0 1.3 GO:0060972 left/right pattern formation(GO:0060972)
0.0 0.8 GO:0008354 germ cell migration(GO:0008354)
0.0 0.9 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0 0.2 GO:0048901 anterior lateral line neuromast development(GO:0048901) anterior lateral line neuromast hair cell differentiation(GO:0048903)
0.0 1.0 GO:0043966 histone H3 acetylation(GO:0043966)
0.0 2.7 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.0 1.2 GO:0007632 visual behavior(GO:0007632)
0.0 2.0 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.0 0.7 GO:0045116 protein neddylation(GO:0045116)
0.0 0.9 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.0 2.4 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.0 1.9 GO:0071391 cellular response to estrogen stimulus(GO:0071391)
0.0 2.4 GO:0002028 regulation of sodium ion transport(GO:0002028)
0.0 0.2 GO:0038093 Fc receptor signaling pathway(GO:0038093)
0.0 1.7 GO:0051453 regulation of intracellular pH(GO:0051453)
0.0 0.6 GO:0045920 negative regulation of exocytosis(GO:0045920)
0.0 0.3 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.0 0.7 GO:0032508 DNA geometric change(GO:0032392) DNA duplex unwinding(GO:0032508)
0.0 0.2 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.9 GO:0007286 spermatid development(GO:0007286)
0.0 0.9 GO:0001878 response to yeast(GO:0001878)
0.0 1.0 GO:0015914 phospholipid transport(GO:0015914)
0.0 1.1 GO:0035329 hippo signaling(GO:0035329)
0.0 4.2 GO:0010466 negative regulation of peptidase activity(GO:0010466)
0.0 0.3 GO:0015810 acidic amino acid transport(GO:0015800) aspartate transport(GO:0015810) L-glutamate transport(GO:0015813) malate-aspartate shuttle(GO:0043490)
0.0 0.8 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.0 1.0 GO:0051014 actin filament severing(GO:0051014)
0.0 2.7 GO:0006334 nucleosome assembly(GO:0006334)
0.0 0.5 GO:0001522 pseudouridine synthesis(GO:0001522)
0.0 0.3 GO:0072028 nephron morphogenesis(GO:0072028)
0.0 0.7 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.0 0.1 GO:0045580 regulation of T cell differentiation(GO:0045580)
0.0 1.0 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.9 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0 0.5 GO:0045841 mitotic spindle assembly checkpoint(GO:0007094) spindle checkpoint(GO:0031577) negative regulation of mitotic metaphase/anaphase transition(GO:0045841) spindle assembly checkpoint(GO:0071173) mitotic spindle checkpoint(GO:0071174)
0.0 2.1 GO:0061640 cytoskeleton-dependent cytokinesis(GO:0061640)
0.0 0.1 GO:0048899 anterior lateral line development(GO:0048899)
0.0 0.4 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0 0.1 GO:0019184 nonribosomal peptide biosynthetic process(GO:0019184)
0.0 0.7 GO:0032543 mitochondrial translation(GO:0032543)
0.0 2.6 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 0.7 GO:0035987 endodermal cell differentiation(GO:0035987)
0.0 1.3 GO:0006261 DNA-dependent DNA replication(GO:0006261)
0.0 0.5 GO:0051289 protein homotetramerization(GO:0051289)
0.0 1.3 GO:0001666 response to hypoxia(GO:0001666)
0.0 1.9 GO:0008360 regulation of cell shape(GO:0008360)
0.0 0.6 GO:0030199 collagen fibril organization(GO:0030199)
0.0 3.0 GO:0042254 ribosome biogenesis(GO:0042254)
0.0 0.2 GO:0046247 carotene metabolic process(GO:0016119) carotene catabolic process(GO:0016121) terpene metabolic process(GO:0042214) terpene catabolic process(GO:0046247)
0.0 2.2 GO:0006821 chloride transport(GO:0006821)
0.0 4.3 GO:0006470 protein dephosphorylation(GO:0006470)
0.0 0.4 GO:0035622 intrahepatic bile duct development(GO:0035622)
0.0 0.8 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436) positive regulation of proteasomal protein catabolic process(GO:1901800)
0.0 0.2 GO:0018216 peptidyl-arginine methylation(GO:0018216)
0.0 0.4 GO:0035118 embryonic pectoral fin morphogenesis(GO:0035118)
0.0 0.1 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.0 0.2 GO:0060729 maintenance of gastrointestinal epithelium(GO:0030277) intestinal epithelial structure maintenance(GO:0060729)
0.0 0.1 GO:0044805 late nucleophagy(GO:0044805)
0.0 1.6 GO:0010038 response to metal ion(GO:0010038)
0.0 2.4 GO:0007204 positive regulation of cytosolic calcium ion concentration(GO:0007204)
0.0 0.3 GO:0051180 vitamin transport(GO:0051180)
0.0 0.7 GO:0007030 Golgi organization(GO:0007030)
0.0 0.1 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.1 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 3.9 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.9 11.1 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.8 2.4 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.7 2.8 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.6 1.9 GO:0042709 succinate-CoA ligase complex(GO:0042709)
0.6 3.1 GO:0005673 transcription factor TFIIE complex(GO:0005673)
0.6 3.1 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.6 2.4 GO:0072588 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.5 3.0 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.5 1.9 GO:0097268 cytoophidium(GO:0097268)
0.5 2.4 GO:0005899 insulin receptor complex(GO:0005899)
0.5 1.8 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.5 2.8 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.4 1.6 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.4 4.7 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.4 1.9 GO:0070390 transcription export complex 2(GO:0070390)
0.4 1.4 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.3 1.6 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.3 1.0 GO:0034457 Mpp10 complex(GO:0034457)
0.3 2.5 GO:0031332 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.3 2.9 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.3 3.2 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.3 2.0 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.3 2.2 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.3 1.6 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.3 1.9 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.3 1.3 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.3 2.6 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.2 1.9 GO:0032797 SMN complex(GO:0032797)
0.2 3.4 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.2 1.1 GO:0070724 BMP receptor complex(GO:0070724)
0.2 0.9 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.2 0.6 GO:0070545 PeBoW complex(GO:0070545)
0.2 0.7 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.2 3.9 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.2 0.5 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.2 9.8 GO:0005643 nuclear pore(GO:0005643)
0.2 2.2 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.2 1.6 GO:0000812 Swr1 complex(GO:0000812)
0.2 8.4 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.1 3.6 GO:0071141 SMAD protein complex(GO:0071141)
0.1 3.0 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.1 1.0 GO:0031616 spindle pole centrosome(GO:0031616)
0.1 0.4 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.1 2.5 GO:0071565 nBAF complex(GO:0071565)
0.1 0.5 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.1 1.5 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.1 24.3 GO:0005730 nucleolus(GO:0005730)
0.1 1.2 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.1 0.4 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.1 0.2 GO:0016529 sarcoplasm(GO:0016528) sarcoplasmic reticulum(GO:0016529)
0.1 3.4 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.1 0.2 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235) anchored component of the cytoplasmic side of the plasma membrane(GO:0098753)
0.1 0.6 GO:0042788 polysomal ribosome(GO:0042788)
0.1 1.0 GO:0000124 SAGA complex(GO:0000124)
0.1 0.8 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.1 0.3 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.1 0.5 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.1 0.4 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.1 8.0 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.1 0.2 GO:0061673 mitotic spindle astral microtubule(GO:0061673)
0.1 3.1 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.1 2.1 GO:0017053 transcriptional repressor complex(GO:0017053)
0.1 0.4 GO:0097225 sperm midpiece(GO:0097225)
0.1 2.1 GO:0005940 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.1 1.7 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.0 5.1 GO:0000786 nucleosome(GO:0000786)
0.0 1.1 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 1.5 GO:0000428 DNA-directed RNA polymerase complex(GO:0000428)
0.0 3.4 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.9 GO:0032039 integrator complex(GO:0032039)
0.0 0.8 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.5 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 1.7 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 2.1 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 2.2 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.5 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.8 GO:0005761 organellar ribosome(GO:0000313) mitochondrial ribosome(GO:0005761)
0.0 0.4 GO:0097346 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202) INO80-type complex(GO:0097346)
0.0 0.5 GO:0044545 NSL complex(GO:0044545)
0.0 1.3 GO:0005758 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.0 4.0 GO:0043296 apical junction complex(GO:0043296)
0.0 0.4 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.0 6.8 GO:0005667 transcription factor complex(GO:0005667)
0.0 2.0 GO:0030139 endocytic vesicle(GO:0030139)
0.0 0.4 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 0.1 GO:0070876 SOSS complex(GO:0070876)
0.0 0.2 GO:0014704 intercalated disc(GO:0014704)
0.0 8.1 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 5.8 GO:0000139 Golgi membrane(GO:0000139)
0.0 1.0 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.7 GO:0031902 late endosome membrane(GO:0031902)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 6.0 GO:0071885 N-terminal protein N-methyltransferase activity(GO:0071885)
1.2 3.7 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
1.1 3.3 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
1.0 4.2 GO:0004639 phosphoribosylaminoimidazolesuccinocarboxamide synthase activity(GO:0004639)
1.0 3.0 GO:0072590 N-acetyl-L-aspartate-L-glutamate ligase activity(GO:0072590) citrate-L-glutamate ligase activity(GO:0072591)
1.0 3.9 GO:0004373 glycogen (starch) synthase activity(GO:0004373)
0.8 2.5 GO:0016743 carboxyl- or carbamoyltransferase activity(GO:0016743)
0.7 2.2 GO:0003913 DNA photolyase activity(GO:0003913)
0.7 5.0 GO:0016426 tRNA (adenine) methyltransferase activity(GO:0016426)
0.7 2.8 GO:0004478 methionine adenosyltransferase activity(GO:0004478)
0.7 3.4 GO:0003980 UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980)
0.7 8.0 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.6 1.9 GO:0004776 succinate-CoA ligase activity(GO:0004774) succinate-CoA ligase (ADP-forming) activity(GO:0004775) succinate-CoA ligase (GDP-forming) activity(GO:0004776)
0.6 3.6 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.5 2.7 GO:0004565 beta-galactosidase activity(GO:0004565)
0.5 1.9 GO:0003883 CTP synthase activity(GO:0003883)
0.5 2.4 GO:0043560 insulin-activated receptor activity(GO:0005009) insulin receptor substrate binding(GO:0043560)
0.5 1.8 GO:0032896 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215) palmitoyl-CoA 9-desaturase activity(GO:0032896)
0.4 3.4 GO:0050072 m7G(5')pppN diphosphatase activity(GO:0050072)
0.4 2.9 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.4 1.6 GO:0034416 bisphosphoglycerate phosphatase activity(GO:0034416)
0.4 1.2 GO:0034618 arginine binding(GO:0034618)
0.4 11.8 GO:0008175 tRNA methyltransferase activity(GO:0008175)
0.4 7.3 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.4 1.5 GO:0034511 U3 snoRNA binding(GO:0034511)
0.4 3.4 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.4 2.9 GO:0015232 heme transporter activity(GO:0015232)
0.4 3.5 GO:0035198 miRNA binding(GO:0035198)
0.3 1.7 GO:0019238 cyclohydrolase activity(GO:0019238)
0.3 2.2 GO:0034632 retinol transporter activity(GO:0034632)
0.3 2.5 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.3 1.5 GO:0004001 adenosine kinase activity(GO:0004001)
0.3 8.3 GO:0034062 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.3 6.3 GO:0102338 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.3 1.1 GO:0033745 L-methionine-(R)-S-oxide reductase activity(GO:0033745)
0.3 5.4 GO:0008301 DNA binding, bending(GO:0008301)
0.3 0.8 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.3 4.4 GO:0004724 magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
0.3 2.4 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.3 1.6 GO:0008502 melatonin receptor activity(GO:0008502)
0.2 0.7 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.2 1.4 GO:0004396 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) glucose binding(GO:0005536) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.2 1.3 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.2 1.5 GO:0008118 N-acetyllactosaminide alpha-2,3-sialyltransferase activity(GO:0008118)
0.2 2.8 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.2 1.7 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.2 0.8 GO:0101006 protein histidine phosphatase activity(GO:0101006)
0.2 10.6 GO:0043022 ribosome binding(GO:0043022)
0.2 1.6 GO:0031419 cobalamin binding(GO:0031419)
0.2 1.0 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
0.2 0.6 GO:0050135 NAD(P)+ nucleosidase activity(GO:0050135)
0.2 2.9 GO:0051117 ATPase binding(GO:0051117)
0.2 2.7 GO:0030515 snoRNA binding(GO:0030515)
0.2 3.3 GO:0051393 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.2 1.0 GO:0032052 bile acid binding(GO:0032052)
0.2 0.9 GO:0004594 pantothenate kinase activity(GO:0004594)
0.2 0.6 GO:0047751 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765) enone reductase activity(GO:0035671) cholestenone 5-alpha-reductase activity(GO:0047751)
0.2 1.7 GO:0015385 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.1 0.4 GO:0016496 substance P receptor activity(GO:0016496)
0.1 2.5 GO:0061608 nuclear import signal receptor activity(GO:0061608)
0.1 2.9 GO:0070411 I-SMAD binding(GO:0070411)
0.1 3.1 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.1 1.2 GO:0051920 peroxiredoxin activity(GO:0051920)
0.1 1.8 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.1 1.7 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.1 0.5 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.1 11.5 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.1 2.7 GO:0016854 racemase and epimerase activity(GO:0016854)
0.1 4.4 GO:0019957 C-C chemokine binding(GO:0019957)
0.1 0.9 GO:0072518 Rho-dependent protein serine/threonine kinase activity(GO:0072518)
0.1 0.8 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.1 0.4 GO:0097016 L27 domain binding(GO:0097016)
0.1 1.4 GO:0016783 sulfurtransferase activity(GO:0016783)
0.1 1.5 GO:0043994 H3 histone acetyltransferase activity(GO:0010484) histone acetyltransferase activity (H3-K23 specific)(GO:0043994)
0.1 2.8 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 1.5 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.1 1.3 GO:0004017 adenylate kinase activity(GO:0004017)
0.1 1.8 GO:0050811 GABA receptor binding(GO:0050811)
0.1 1.1 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.1 1.1 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.1 2.8 GO:0035014 phosphatidylinositol 3-kinase regulator activity(GO:0035014)
0.1 0.5 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.1 1.3 GO:0035497 cAMP response element binding(GO:0035497)
0.1 0.9 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.1 0.9 GO:0005163 nerve growth factor receptor binding(GO:0005163) neurotrophin receptor binding(GO:0005165)
0.1 0.9 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.1 7.2 GO:0019905 syntaxin binding(GO:0019905)
0.1 0.7 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.1 0.5 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.1 0.2 GO:0004422 hypoxanthine phosphoribosyltransferase activity(GO:0004422)
0.1 0.8 GO:0090482 vitamin transmembrane transporter activity(GO:0090482)
0.1 7.7 GO:0015171 amino acid transmembrane transporter activity(GO:0015171)
0.1 0.3 GO:0031708 endothelin B receptor binding(GO:0031708)
0.1 2.5 GO:0005548 phospholipid transporter activity(GO:0005548)
0.1 0.8 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.1 3.4 GO:0031625 ubiquitin protein ligase binding(GO:0031625)
0.1 4.1 GO:0003724 RNA helicase activity(GO:0003724)
0.1 1.2 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.0 1.0 GO:0016251 obsolete general RNA polymerase II transcription factor activity(GO:0016251)
0.0 0.8 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 5.6 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.5 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 1.1 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.0 0.5 GO:0005522 profilin binding(GO:0005522)
0.0 0.8 GO:0070122 isopeptidase activity(GO:0070122)
0.0 0.2 GO:0035242 protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.0 2.0 GO:0071949 FAD binding(GO:0071949)
0.0 1.4 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.0 1.2 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.6 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0 0.5 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.0 1.5 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.5 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 1.2 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.4 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.0 2.8 GO:0016278 lysine N-methyltransferase activity(GO:0016278) protein-lysine N-methyltransferase activity(GO:0016279)
0.0 0.2 GO:0004960 thromboxane receptor activity(GO:0004960)
0.0 1.3 GO:0005347 ATP transmembrane transporter activity(GO:0005347)
0.0 0.7 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 1.1 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 2.2 GO:0030170 pyridoxal phosphate binding(GO:0030170)
0.0 6.7 GO:0042393 histone binding(GO:0042393)
0.0 0.5 GO:0015665 alcohol transmembrane transporter activity(GO:0015665)
0.0 0.5 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.0 0.3 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 2.4 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 0.3 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.0 0.2 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 1.1 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 4.8 GO:0046982 protein heterodimerization activity(GO:0046982)
0.0 1.0 GO:0051540 iron-sulfur cluster binding(GO:0051536) metal cluster binding(GO:0051540)
0.0 0.6 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 7.6 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 1.6 GO:0004386 helicase activity(GO:0004386)
0.0 0.6 GO:0043021 ribonucleoprotein complex binding(GO:0043021)
0.0 1.0 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.1 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.0 1.4 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 4.2 GO:0044822 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 2.5 GO:0008168 methyltransferase activity(GO:0008168)
0.0 2.2 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds(GO:0004553)
0.0 0.6 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.2 GO:0010436 beta-carotene 15,15'-monooxygenase activity(GO:0003834) carotenoid dioxygenase activity(GO:0010436)
0.0 0.1 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
0.0 0.5 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 1.0 GO:0042803 protein homodimerization activity(GO:0042803)
0.0 0.1 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 3.0 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.4 GO:0016798 hydrolase activity, acting on glycosyl bonds(GO:0016798)
0.0 2.0 GO:0015293 symporter activity(GO:0015293)
0.0 1.8 GO:0000287 magnesium ion binding(GO:0000287)
0.0 0.6 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.3 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 6.7 GO:0005525 GTP binding(GO:0005525)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 5.3 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.3 7.4 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.2 15.3 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.2 6.5 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.2 2.6 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.1 0.6 SIG PIP3 SIGNALING IN CARDIAC MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.1 1.5 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.1 3.5 PID FOXO PATHWAY FoxO family signaling
0.1 1.8 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.1 1.5 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.1 1.0 PID MYC PATHWAY C-MYC pathway
0.1 4.1 PID CMYB PATHWAY C-MYB transcription factor network
0.1 2.6 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.1 1.0 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 1.3 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 1.4 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 2.0 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 1.1 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 0.4 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.3 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.0 0.5 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 1.4 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 10.8 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.7 11.1 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.5 6.0 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.5 8.3 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.4 7.6 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.4 12.0 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.4 5.2 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.3 5.1 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.3 2.9 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.2 4.7 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.2 3.0 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.2 1.8 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.2 8.1 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.2 1.3 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.2 1.4 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.2 3.2 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 1.8 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.1 4.5 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.1 1.7 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.1 1.5 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.1 2.6 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.1 7.1 REACTOME DIABETES PATHWAYS Genes involved in Diabetes pathways
0.1 8.2 REACTOME LATE PHASE OF HIV LIFE CYCLE Genes involved in Late Phase of HIV Life Cycle
0.1 4.1 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.1 2.7 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.1 1.8 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.1 3.4 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.1 0.6 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 1.9 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.1 2.5 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.1 1.1 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.1 1.7 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.1 1.0 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.1 2.1 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.1 0.9 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.1 0.6 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.1 1.6 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.1 2.9 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.1 2.0 REACTOME RNA POL I RNA POL III AND MITOCHONDRIAL TRANSCRIPTION Genes involved in RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription
0.1 1.0 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.1 1.5 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.1 1.4 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.1 1.8 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.1 0.7 REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION Genes involved in Cyclin E associated events during G1/S transition
0.1 0.7 REACTOME BASE EXCISION REPAIR Genes involved in Base Excision Repair
0.0 1.9 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.5 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 3.7 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 0.8 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 1.9 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.2 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.5 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.3 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.3 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.6 REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.0 1.7 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.3 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS Genes involved in CREB phosphorylation through the activation of Ras
0.0 0.2 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.2 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.0 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0 1.3 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 1.0 REACTOME SIGNALING BY EGFR IN CANCER Genes involved in Signaling by EGFR in Cancer
0.0 0.5 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis