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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for crx+otx1

Z-value: 1.04

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Transcription factors associated with crx+otx1

Gene Symbol Gene ID Gene Info
crx
ENSDARG00000011989 cone-rod homeobox
otx1
ENSDARG00000094992 orthodenticle homeobox 1
crx
ENSDARG00000113850 cone-rod homeobox

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
otx1dr11_v1_chr17_+_24318753_243187530.947.8e-09Click!
crxdr11_v1_chr5_+_36932718_36932718-0.735.9e-04Click!

Activity profile of crx+otx1 motif

Sorted Z-values of crx+otx1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr11_-_1550709 4.09 ENSDART00000110097
si:ch73-303b9.1
si:ch73-303b9.1
chr13_+_8840772 3.93 ENSDART00000059321
epcam
epithelial cell adhesion molecule
chr17_-_45125537 3.82 ENSDART00000113552
zgc:163014
zgc:163014
chr10_-_42898220 3.27 ENSDART00000099270
CU326366.2

chr16_-_46579936 2.86 ENSDART00000166143
ENSDART00000127212
si:dkey-152b24.6
si:dkey-152b24.6
chr19_+_42898239 2.77 ENSDART00000051724
arpp21
cAMP-regulated phosphoprotein, 21
chr13_-_36844945 2.66 ENSDART00000129562
ENSDART00000150899
nin
ninein (GSK3B interacting protein)
chr22_+_25453334 2.34 ENSDART00000123962
si:ch211-12h2.6
si:ch211-12h2.6
chr14_+_30340251 2.32 ENSDART00000148448
mtus1a
microtubule associated tumor suppressor 1a
chr6_+_37655078 2.30 ENSDART00000122199
ENSDART00000065127
cyfip1
cytoplasmic FMR1 interacting protein 1
chr9_-_8314028 2.21 ENSDART00000102739
si:ch211-145c1.1
si:ch211-145c1.1
chr20_+_1272526 2.18 ENSDART00000008115
ENSDART00000133825
hsd3b2
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
chr7_-_26518086 2.18 ENSDART00000058913
eif4a1a
eukaryotic translation initiation factor 4A1A
chr5_-_69180587 2.03 ENSDART00000156681
ENSDART00000160753
zgc:171967
zgc:171967
chr20_-_54014373 1.96 ENSDART00000152934
si:dkey-241l7.6
si:dkey-241l7.6
chr18_+_27439680 1.95 ENSDART00000014726
tp53i11b
tumor protein p53 inducible protein 11b
chr20_-_20932760 1.89 ENSDART00000152415
ENSDART00000039907
btbd6b
BTB (POZ) domain containing 6b
chr1_-_45215343 1.85 ENSDART00000014727
ddx39aa
DEAD (Asp-Glu-Ala-Asp) box polypeptide 39Aa
chr1_-_43712120 1.82 ENSDART00000074600
SLC9B2
si:dkey-162b23.4
chr5_-_69180227 1.78 ENSDART00000154816
zgc:171967
zgc:171967
chr11_-_25257595 1.77 ENSDART00000123567
snai1a
snail family zinc finger 1a
chr1_-_38170997 1.76 ENSDART00000142811
hmgb2a
high mobility group box 2a
chr20_-_54014539 1.74 ENSDART00000060466
si:dkey-241l7.6
si:dkey-241l7.6
chr3_-_26184018 1.69 ENSDART00000191604
si:ch211-11k18.4
si:ch211-11k18.4
chr1_+_52633367 1.63 ENSDART00000134658
slc44a1a
solute carrier family 44 (choline transporter), member 1a
chr2_+_44972720 1.54 ENSDART00000075146
alg3
asparagine-linked glycosylation 3 (alpha-1,3-mannosyltransferase)
chr23_+_21492151 1.53 ENSDART00000025487
icmt
isoprenylcysteine carboxyl methyltransferase
chr11_+_19080400 1.52 ENSDART00000044423
magi1b
membrane associated guanylate kinase, WW and PDZ domain containing 1b
chr3_-_26183699 1.51 ENSDART00000147517
ENSDART00000140731
si:ch211-11k18.4
si:ch211-11k18.4
chr14_-_31694274 1.46 ENSDART00000173353
map7d3
MAP7 domain containing 3
chr7_-_39378903 1.45 ENSDART00000173659
slc8b1
solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
chr5_-_32489796 1.45 ENSDART00000168870
gpr107
G protein-coupled receptor 107
chr25_+_7532627 1.38 ENSDART00000187660
ptdss2
phosphatidylserine synthase 2
chr3_-_3366590 1.34 ENSDART00000109428
ENSDART00000175329
si:dkey-46g23.1
si:dkey-46g23.1
chr5_-_23715027 1.29 ENSDART00000139020
gbgt1l1
globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 1
chr3_-_15679107 1.24 ENSDART00000080441
zgc:66443
zgc:66443
chr14_-_6402769 1.22 ENSDART00000121552
slc44a1b
solute carrier family 44 (choline transporter), member 1b
chr22_-_38934989 1.22 ENSDART00000008365
ncbp2
nuclear cap binding protein subunit 2
chr2_+_15069011 1.20 ENSDART00000145893
cnn3b
calponin 3, acidic b
chr7_+_22330466 1.17 ENSDART00000187347
ENSDART00000174483
fgf11a
fibroblast growth factor 11a
chr14_+_14027427 1.17 ENSDART00000183204
rraga
Ras-related GTP binding A
chr23_-_3759345 1.17 ENSDART00000132205
ENSDART00000137707
ENSDART00000189382
hmga1a
high mobility group AT-hook 1a
chr9_+_1365747 1.16 ENSDART00000140917
ENSDART00000036605
prkra
protein kinase, interferon-inducible double stranded RNA dependent activator
chr15_+_20355465 1.12 ENSDART00000143092
ENSDART00000062666
il15l
interleukin 15, like
chr4_-_28353538 1.09 ENSDART00000064219
trmu
tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
chr16_+_14201401 1.08 ENSDART00000113679
dap3
death associated protein 3
chr22_-_12304591 1.07 ENSDART00000136408
zranb3
zinc finger, RAN-binding domain containing 3
chr22_+_30047245 1.05 ENSDART00000142857
ENSDART00000141247
ENSDART00000140015
ENSDART00000040538
add3a
adducin 3 (gamma) a
chr8_+_2656681 1.04 ENSDART00000185067
ENSDART00000165943
fam102aa
family with sequence similarity 102, member Aa
chr5_-_23715861 1.04 ENSDART00000019992
gbgt1l1
globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 1
chr8_+_2656231 1.04 ENSDART00000160833
fam102aa
family with sequence similarity 102, member Aa
chr21_+_43702016 1.04 ENSDART00000017176
dkc1
dyskeratosis congenita 1, dyskerin
chr15_-_26930999 1.03 ENSDART00000181674
ENSDART00000126046
ccdc9
coiled-coil domain containing 9
chr16_+_19637384 1.03 ENSDART00000184773
ENSDART00000191895
ENSDART00000182020
ENSDART00000135359
macc1
metastasis associated in colon cancer 1
chr14_-_36412473 1.02 ENSDART00000128244
ENSDART00000138376
asb5a
ankyrin repeat and SOCS box containing 5a
chr9_-_46276626 1.02 ENSDART00000165238
hdac4
histone deacetylase 4
chr12_+_23850661 1.02 ENSDART00000152921
svila
supervillin a
chr1_-_24349759 1.01 ENSDART00000142740
ENSDART00000177989
lrba
LPS-responsive vesicle trafficking, beach and anchor containing
chr23_-_3759692 1.00 ENSDART00000028885
hmga1a
high mobility group AT-hook 1a
chr15_-_26931541 1.00 ENSDART00000027563
ccdc9
coiled-coil domain containing 9
chr16_+_53519048 1.00 ENSDART00000124691
smpd5
sphingomyelin phosphodiesterase 5
chr18_+_173603 1.00 ENSDART00000185918
larp6a
La ribonucleoprotein domain family, member 6a
chr8_+_28724692 1.00 ENSDART00000140115
ccser1
coiled-coil serine-rich protein 1
chr13_+_15581270 0.97 ENSDART00000189880
ENSDART00000190067
ENSDART00000041293
mark3a
MAP/microtubule affinity-regulating kinase 3a
chr24_+_10039165 0.96 ENSDART00000144186
pou6f2
POU class 6 homeobox 2
chr18_+_3634652 0.96 ENSDART00000159913
lrch3
leucine-rich repeats and calponin homology (CH) domain containing 3
chr5_-_22868650 0.94 ENSDART00000057541
apool
apolipoprotein O-like
chr23_+_2560005 0.93 ENSDART00000186906
GGT7
gamma-glutamyltransferase 7
chr24_-_31140356 0.92 ENSDART00000167837
tmem56a
transmembrane protein 56a
chr2_-_31686353 0.92 ENSDART00000126177
ENSDART00000056679
e2f5
E2F transcription factor 5
chr10_+_42898103 0.92 ENSDART00000015872
zcchc9
zinc finger, CCHC domain containing 9
chr17_+_50701748 0.89 ENSDART00000191938
ENSDART00000183220
ENSDART00000049464
fermt2
fermitin family member 2
chr13_+_1015749 0.88 ENSDART00000190982
prokr1b
prokineticin receptor 1b
chr13_+_6189203 0.88 ENSDART00000109665
ppm1g
protein phosphatase, Mg2+/Mn2+ dependent, 1G
chr13_-_36050303 0.88 ENSDART00000134955
ENSDART00000139087
lgmn
legumain
chr8_-_4618653 0.88 ENSDART00000025535
sept5a
septin 5a
chr2_-_39036604 0.84 ENSDART00000129963
rbp1
retinol binding protein 1b, cellular
chr5_+_51833305 0.84 ENSDART00000165276
ENSDART00000166443
papd4
PAP associated domain containing 4
chr5_-_52216170 0.83 ENSDART00000158542
ENSDART00000192981
lnpep
leucyl/cystinyl aminopeptidase
chr2_+_24080694 0.82 ENSDART00000024058
kcnh2a
potassium voltage-gated channel, subfamily H (eag-related), member 2a
chr4_-_11053543 0.81 ENSDART00000067262
mettl25
methyltransferase like 25
chr23_-_42876596 0.80 ENSDART00000086156
dlgap4a
discs, large (Drosophila) homolog-associated protein 4a
chr11_-_27821 0.77 ENSDART00000158769
ENSDART00000172970
ENSDART00000173118
ENSDART00000168674
ENSDART00000163545
ENSDART00000173411
ENSDART00000172132
sp1
sp1 transcription factor
chr25_+_35891342 0.77 ENSDART00000147093
lsm14aa
LSM14A mRNA processing body assembly factor a
chr18_-_2222128 0.75 ENSDART00000171402
pigb
phosphatidylinositol glycan anchor biosynthesis, class B
chr21_-_28340977 0.75 ENSDART00000141629
nrxn2a
neurexin 2a
chr2_-_30721502 0.73 ENSDART00000132389
si:dkey-94e7.1
si:dkey-94e7.1
chr15_-_5580093 0.73 ENSDART00000143726
wdr62
WD repeat domain 62
chr5_-_27993972 0.70 ENSDART00000175819
ppp3cca
protein phosphatase 3, catalytic subunit, gamma isozyme, a
chr3_+_62000822 0.69 ENSDART00000106680
rai1
retinoic acid induced 1
chr14_+_2487672 0.69 ENSDART00000170629
ENSDART00000123063
fgf18a
fibroblast growth factor 18a
chr25_-_32363341 0.68 ENSDART00000153892
ENSDART00000114385
cep152
centrosomal protein 152
chr24_-_38079261 0.67 ENSDART00000105662
crp1
C-reactive protein 1
chr23_+_39963599 0.66 ENSDART00000166539
fyco1a
FYVE and coiled-coil domain containing 1a
chr7_+_39011852 0.66 ENSDART00000093009
dgkza
diacylglycerol kinase, zeta a
chr3_-_15210491 0.65 ENSDART00000037906
hirip3
HIRA interacting protein 3
chr25_-_16782394 0.64 ENSDART00000019413
ndufa9a
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9a
chr9_-_5318873 0.62 ENSDART00000129308
ACVR1C
activin A receptor type 1C
chr1_+_23162124 0.61 ENSDART00000188428
si:dkey-92j12.5
si:dkey-92j12.5
chr5_+_51833132 0.61 ENSDART00000167491
papd4
PAP associated domain containing 4
chr2_-_32387441 0.61 ENSDART00000148202
ubtfl
upstream binding transcription factor, like
chr23_+_1181248 0.59 ENSDART00000170942
utrn
utrophin
chr19_-_2876321 0.58 ENSDART00000159253
exosc7
exosome component 7
chr7_-_30492261 0.57 ENSDART00000173954
adam10a
ADAM metallopeptidase domain 10a
chr9_+_7030016 0.56 ENSDART00000148047
ENSDART00000148181
inpp4aa
inositol polyphosphate-4-phosphatase type I Aa
chr8_+_18545933 0.55 ENSDART00000148806
tab3
TGF-beta activated kinase 1/MAP3K7 binding protein 3
chr19_+_43884120 0.54 ENSDART00000139684
ENSDART00000142312
lypla2
lysophospholipase II
chr25_-_13549577 0.54 ENSDART00000166772
ano10b
anoctamin 10b
chr7_+_39011355 0.54 ENSDART00000173855
dgkza
diacylglycerol kinase, zeta a
chr6_-_1780633 0.53 ENSDART00000160670
ntan1
N-terminal asparagine amidase
chr16_+_33987892 0.53 ENSDART00000166302
pigv
phosphatidylinositol glycan anchor biosynthesis, class V
chr3_+_32842825 0.52 ENSDART00000122228
prr14
proline rich 14
chr20_+_13969414 0.52 ENSDART00000049864
rd3
retinal degeneration 3
chr13_+_2442841 0.50 ENSDART00000114456
ENSDART00000137124
ENSDART00000193737
ENSDART00000189722
ENSDART00000187485
arfgef3
ARFGEF family member 3
chr19_-_7540821 0.49 ENSDART00000143958
lix1l
limb and CNS expressed 1 like
chr23_-_437467 0.49 ENSDART00000192106
tspan2b
tetraspanin 2b
chr21_-_40562705 0.49 ENSDART00000158289
ENSDART00000171997
taok1b
TAO kinase 1b
chr2_-_15349382 0.48 ENSDART00000057238
olfm3b
olfactomedin 3b
chr21_-_40317035 0.47 ENSDART00000143648
ENSDART00000013359
or101-1
odorant receptor, family B, subfamily 101, member 1
chr13_+_41917606 0.46 ENSDART00000114741
polr1b
polymerase (RNA) I polypeptide B
chr20_+_42537768 0.45 ENSDART00000134066
ENSDART00000153434
si:dkeyp-93d12.1
si:dkeyp-93d12.1
chr10_-_25028527 0.43 ENSDART00000040733
cd209
CD209 molecule
chr1_+_44523516 0.43 ENSDART00000147702
zdhhc5a
zinc finger, DHHC-type containing 5a
chr7_-_30492018 0.42 ENSDART00000099639
ENSDART00000162705
ENSDART00000173663
adam10a
ADAM metallopeptidase domain 10a
chr23_+_12361899 0.42 ENSDART00000143728
pigt
phosphatidylinositol glycan anchor biosynthesis, class T
chr10_-_41400049 0.42 ENSDART00000009838
gpat4
glycerol-3-phosphate acyltransferase 4
chr9_-_135774 0.41 ENSDART00000160435
FQ377903.1

chr4_+_5196469 0.41 ENSDART00000067386
rad51ap1
RAD51 associated protein 1
chr21_-_2209012 0.40 ENSDART00000158345
zgc:162971
zgc:162971
chr10_+_6013076 0.40 ENSDART00000167613
ENSDART00000159216
hmgcs1
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
chr9_+_21151138 0.39 ENSDART00000133903
hao2
hydroxyacid oxidase 2 (long chain)
chr9_-_2945008 0.38 ENSDART00000183452
zak
sterile alpha motif and leucine zipper containing kinase AZK
chr13_+_24579108 0.38 ENSDART00000001830
echs1
enoyl CoA hydratase, short chain, 1, mitochondrial
chr19_+_34169055 0.36 ENSDART00000135592
ENSDART00000186043
poc1bl
POC1 centriolar protein homolog B (Chlamydomonas), like
chr22_+_1170294 0.36 ENSDART00000159761
ENSDART00000169809
irf6
interferon regulatory factor 6
chr6_-_10168822 0.35 ENSDART00000151016
b3galt1a
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1a
chr25_-_10629940 0.33 ENSDART00000154483
ENSDART00000155231
ppp6r3
protein phosphatase 6, regulatory subunit 3
chr16_+_38159758 0.33 ENSDART00000058666
ENSDART00000112165
pi4kb
phosphatidylinositol 4-kinase, catalytic, beta
chr9_+_17982737 0.32 ENSDART00000192569
akap11
A kinase (PRKA) anchor protein 11
chr22_-_16154771 0.32 ENSDART00000009464
slc30a7
solute carrier family 30 (zinc transporter), member 7
chr13_-_9101236 0.32 ENSDART00000163266
HTRA2 (1 of many)
si:dkey-19p15.4
chr4_+_11053301 0.30 ENSDART00000140362
ccdc59
coiled-coil domain containing 59
chr9_-_394088 0.30 ENSDART00000169014
si:dkey-11f4.7
si:dkey-11f4.7
chr4_-_17353100 0.30 ENSDART00000134467
ENSDART00000189019
parpbp
PARP1 binding protein
chr19_-_32641725 0.27 ENSDART00000165006
ENSDART00000188185
hpca
hippocalcin
chr15_-_18213515 0.27 ENSDART00000101635
btr21
bloodthirsty-related gene family, member 21
chr20_-_54924593 0.27 ENSDART00000151522
si:dkey-15f23.1
si:dkey-15f23.1
chr18_+_2554666 0.27 ENSDART00000167218
p2ry2.1
purinergic receptor P2Y2, tandem duplicate 1
chr11_-_15090118 0.26 ENSDART00000171118
slc1a8a
solute carrier family 1 (glutamate transporter), member 8a
chr6_+_37623693 0.26 ENSDART00000144812
ENSDART00000182709
tubgcp5
tubulin, gamma complex associated protein 5
chr4_+_36083288 0.26 ENSDART00000172017
si:ch211-271g18.4
si:ch211-271g18.4
chr21_-_18262287 0.25 ENSDART00000176716
vav2
vav 2 guanine nucleotide exchange factor
chr5_-_65037525 0.25 ENSDART00000158856
anxa1b
annexin A1b
chr14_+_11289851 0.24 ENSDART00000113567
rlim
ring finger protein, LIM domain interacting
chr17_-_1705013 0.24 ENSDART00000182864
CABZ01086293.1

chr11_-_27702778 0.23 ENSDART00000045942
ENSDART00000125352
phf2
PHD finger protein 2
chr24_-_25098719 0.23 ENSDART00000193651
phldb2b
pleckstrin homology-like domain, family B, member 2b
chr17_+_30448452 0.23 ENSDART00000153939
lpin1
lipin 1
chr18_-_6975175 0.21 ENSDART00000134194
si:dkey-266m15.6
si:dkey-266m15.6
chr4_+_63484571 0.20 ENSDART00000169518
ENSDART00000168681
si:dkey-11d20.1
si:dkey-11d20.1
chr11_-_15090564 0.19 ENSDART00000162079
slc1a8a
solute carrier family 1 (glutamate transporter), member 8a
chr5_-_65037371 0.19 ENSDART00000170560
anxa1b
annexin A1b
chr1_+_59328030 0.18 ENSDART00000172464
CABZ01052576.1

chr2_-_26499842 0.18 ENSDART00000186929
BX569796.1

chr10_+_17026870 0.17 ENSDART00000184529
ENSDART00000157480
CR855996.2

chr8_-_46572298 0.17 ENSDART00000030470
sult1st3
sulfotransferase family 1, cytosolic sulfotransferase 3
chr10_+_26652859 0.16 ENSDART00000079174
htatsf1
HIV-1 Tat specific factor 1
chr9_-_3519253 0.16 ENSDART00000169586
dcaf17
ddb1 and cul4 associated factor 17
chr5_+_11407504 0.14 ENSDART00000186723
ENSDART00000018047
zgc:112294
zgc:112294
chr4_-_3805992 0.14 ENSDART00000190125
si:dkey-61f9.1
si:dkey-61f9.1
chr25_-_10630496 0.14 ENSDART00000153639
ENSDART00000181722
ENSDART00000177834
ppp6r3
protein phosphatase 6, regulatory subunit 3
chr8_-_36387378 0.14 ENSDART00000102847
ENSDART00000140959
si:zfos-2070c2.1
si:zfos-2070c2.1
chr6_-_28980756 0.14 ENSDART00000014661
glmnb
glomulin, FKBP associated protein b
chr2_-_37537887 0.14 ENSDART00000143496
ENSDART00000025841
arhgef18a
rho/rac guanine nucleotide exchange factor (GEF) 18a
chr3_+_22327738 0.13 ENSDART00000055675
gh1
growth hormone 1
chr4_+_17353714 0.13 ENSDART00000136299
nup37
nucleoporin 37
chr15_+_887032 0.13 ENSDART00000156395
si:dkey-7i4.9
si:dkey-7i4.9
chr2_+_36112273 0.13 ENSDART00000191315
traj35
T-cell receptor alpha joining 35
chr21_+_13366353 0.13 ENSDART00000151630
si:ch73-62l21.1
si:ch73-62l21.1
chr20_-_36617313 0.12 ENSDART00000172395
ENSDART00000152856
enah
enabled homolog (Drosophila)
chr16_+_46497149 0.12 ENSDART00000135151
ENSDART00000058324
rpz4
rapunzel 4
chr11_+_29770966 0.12 ENSDART00000088624
ENSDART00000124471
rpgrb
retinitis pigmentosa GTPase regulator b
chr4_+_43408004 0.12 ENSDART00000150476
si:dkeyp-53e4.2
si:dkeyp-53e4.2
chr8_+_25091407 0.11 ENSDART00000143922
atxn7l2b
ataxin 7-like 2b
chr23_-_45501177 0.11 ENSDART00000150103
col24a1
collagen type XXIV alpha 1
chr13_-_30161684 0.11 ENSDART00000040409
ppa1b
pyrophosphatase (inorganic) 1b
chr11_-_7355995 0.11 ENSDART00000156595
si:dkey-197i20.6
si:dkey-197i20.6
chr8_-_45430817 0.11 ENSDART00000150067
ENSDART00000112394
ywhabb
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide b
chr4_-_73561848 0.11 ENSDART00000174210
CU570689.2

chr1_+_28031697 0.10 ENSDART00000047211
ENSDART00000149785
ENSDART00000149817
ENSDART00000149479
ENSDART00000187922
chst10
carbohydrate sulfotransferase 10
chr7_-_54320088 0.10 ENSDART00000172396
fadd
Fas (tnfrsf6)-associated via death domain
chr22_+_17203752 0.10 ENSDART00000143376
rab3b
RAB3B, member RAS oncogene family
chr25_-_10610961 0.10 ENSDART00000153474
ppp6r3
protein phosphatase 6, regulatory subunit 3
chr3_+_50602866 0.09 ENSDART00000190069
ENSDART00000153921
gsg1l2a
gsg1-like 2a
chr20_+_53577502 0.09 ENSDART00000126983
myh6
myosin, heavy chain 6, cardiac muscle, alpha
chr1_-_33353778 0.09 ENSDART00000041191
gyg2
glycogenin 2
chr8_+_22404981 0.08 ENSDART00000185211
ENSDART00000099972
si:dkey-23c22.7
si:dkey-23c22.9
si:dkey-23c22.7
si:dkey-23c22.9
chr22_-_619711 0.08 ENSDART00000192778
srsf3b
serine/arginine-rich splicing factor 3b
chr4_+_65281752 0.08 ENSDART00000183934
znf1027
zinc finger protein 1027
chr4_+_44808133 0.08 ENSDART00000184430
znf1107
zinc finger protein 1107

Network of associatons between targets according to the STRING database.

First level regulatory network of crx+otx1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.3 GO:0099563 modification of synaptic structure(GO:0099563)
0.5 2.7 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
0.4 1.2 GO:0046833 regulation of nucleobase-containing compound transport(GO:0032239) positive regulation of nucleobase-containing compound transport(GO:0032241) positive regulation of nucleocytoplasmic transport(GO:0046824) regulation of RNA export from nucleus(GO:0046831) positive regulation of RNA export from nucleus(GO:0046833)
0.4 1.2 GO:2000425 regulation of apoptotic cell clearance(GO:2000425)
0.3 1.0 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.3 1.1 GO:0070900 mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864)
0.3 1.0 GO:0090299 regulation of neural crest formation(GO:0090299)
0.2 0.9 GO:0045668 negative regulation of osteoblast differentiation(GO:0045668)
0.2 0.6 GO:1901004 ubiquinone-6 metabolic process(GO:1901004) ubiquinone-6 biosynthetic process(GO:1901006)
0.2 0.6 GO:0071047 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476) nuclear polyadenylation-dependent mRNA catabolic process(GO:0071042) polyadenylation-dependent mRNA catabolic process(GO:0071047)
0.2 1.2 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
0.2 1.1 GO:0048478 replication fork protection(GO:0048478)
0.1 0.4 GO:0002468 dendritic cell antigen processing and presentation(GO:0002468)
0.1 1.5 GO:0018410 C-terminal protein amino acid modification(GO:0018410)
0.1 2.4 GO:0030259 lipid glycosylation(GO:0030259)
0.1 1.4 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.1 0.7 GO:0098535 de novo centriole assembly(GO:0098535)
0.1 0.7 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.1 0.4 GO:1902767 farnesyl diphosphate biosynthetic process, mevalonate pathway(GO:0010142) isoprenoid biosynthetic process via mevalonate(GO:1902767)
0.1 1.8 GO:0008078 mesodermal cell migration(GO:0008078)
0.1 3.9 GO:0048920 posterior lateral line neuromast primordium migration(GO:0048920)
0.1 1.0 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.1 0.8 GO:0034063 stress granule assembly(GO:0034063)
0.1 1.2 GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein(GO:0042531)
0.1 0.3 GO:0070255 regulation of mucus secretion(GO:0070255) positive regulation of mucus secretion(GO:0070257)
0.1 1.2 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.1 1.3 GO:0045974 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.1 0.2 GO:0061187 regulation of chromatin silencing at rDNA(GO:0061187) negative regulation of chromatin silencing at rDNA(GO:0061188)
0.1 0.9 GO:0030431 sleep(GO:0030431)
0.1 0.4 GO:0033032 neutrophil apoptotic process(GO:0001781) regulation of T-helper 1 type immune response(GO:0002825) positive regulation of T-helper 1 type immune response(GO:0002827) negative regulation of type 2 immune response(GO:0002829) inflammatory cell apoptotic process(GO:0006925) regulation of prostaglandin biosynthetic process(GO:0031392) positive regulation of prostaglandin biosynthetic process(GO:0031394) regulation of phospholipase A2 activity(GO:0032429) interleukin-2 production(GO:0032623) regulation of interleukin-2 production(GO:0032663) positive regulation of interleukin-2 production(GO:0032743) myeloid cell apoptotic process(GO:0033028) regulation of neutrophil apoptotic process(GO:0033029) positive regulation of neutrophil apoptotic process(GO:0033031) regulation of myeloid cell apoptotic process(GO:0033032) positive regulation of myeloid cell apoptotic process(GO:0033034) T-helper 1 type immune response(GO:0042088) positive regulation of CD4-positive, alpha-beta T cell differentiation(GO:0043372) T-helper 1 cell differentiation(GO:0045063) positive regulation of T-helper cell differentiation(GO:0045624) regulation of T-helper 1 cell differentiation(GO:0045625) positive regulation of T-helper 1 cell differentiation(GO:0045627) regulation of T-helper 2 cell differentiation(GO:0045628) negative regulation of T-helper 2 cell differentiation(GO:0045629) positive regulation of fatty acid biosynthetic process(GO:0045723) positive regulation of alpha-beta T cell differentiation(GO:0046638) neutrophil clearance(GO:0097350) negative regulation of phospholipase A2 activity(GO:1900138) positive regulation of CD4-positive, alpha-beta T cell activation(GO:2000516) regulation of unsaturated fatty acid biosynthetic process(GO:2001279) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.1 0.4 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.1 2.2 GO:0002183 cytoplasmic translational initiation(GO:0002183)
0.1 1.3 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.1 1.2 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.3 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.0 0.8 GO:0098962 regulation of postsynaptic neurotransmitter receptor activity(GO:0098962)
0.0 2.1 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 0.5 GO:0002084 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.0 0.9 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.1 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.0 1.0 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.0 1.3 GO:0071427 mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.0 0.6 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0 0.3 GO:0071260 cellular response to mechanical stimulus(GO:0071260)
0.0 0.1 GO:0030186 melatonin metabolic process(GO:0030186)
0.0 0.9 GO:0055008 cardiac muscle tissue morphogenesis(GO:0055008)
0.0 0.8 GO:0043171 peptide catabolic process(GO:0043171)
0.0 2.2 GO:0006694 steroid biosynthetic process(GO:0006694)
0.0 0.1 GO:0036462 TRAIL-activated apoptotic signaling pathway(GO:0036462)
0.0 0.3 GO:0030309 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.0 0.1 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) collagen-activated signaling pathway(GO:0038065)
0.0 1.6 GO:0007605 sensory perception of sound(GO:0007605)
0.0 0.5 GO:0097352 autophagosome maturation(GO:0097352)
0.0 0.5 GO:0097194 execution phase of apoptosis(GO:0097194)
0.0 0.7 GO:0032922 circadian regulation of gene expression(GO:0032922)
0.0 0.1 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0 0.1 GO:0055014 atrial cardiac muscle cell development(GO:0055014)
0.0 1.4 GO:0072583 clathrin-mediated endocytosis(GO:0072583)
0.0 3.2 GO:0016197 endosomal transport(GO:0016197)
0.0 0.4 GO:0036297 interstrand cross-link repair(GO:0036297)
0.0 0.4 GO:0048702 embryonic neurocranium morphogenesis(GO:0048702)
0.0 0.3 GO:0007020 microtubule nucleation(GO:0007020)
0.0 0.5 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.1 GO:0046548 retinal rod cell development(GO:0046548)
0.0 1.1 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.0 0.3 GO:0006829 zinc II ion transport(GO:0006829)
0.0 0.2 GO:0006584 catecholamine metabolic process(GO:0006584) catechol-containing compound metabolic process(GO:0009712)
0.0 0.3 GO:0060872 semicircular canal development(GO:0060872)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0031429 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.2 1.2 GO:0034448 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.2 0.7 GO:0098536 deuterosome(GO:0098536)
0.2 2.7 GO:0097431 mitotic spindle pole(GO:0097431)
0.2 1.2 GO:0034518 RNA cap binding complex(GO:0034518)
0.2 2.3 GO:0031209 SCAR complex(GO:0031209)
0.1 0.9 GO:0031258 lamellipodium membrane(GO:0031258)
0.1 0.8 GO:0005955 calcineurin complex(GO:0005955)
0.1 0.5 GO:0031501 mannosyltransferase complex(GO:0031501)
0.1 0.4 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.1 0.3 GO:0008274 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.1 0.6 GO:0000177 nuclear exosome (RNase complex)(GO:0000176) cytoplasmic exosome (RNase complex)(GO:0000177)
0.1 0.8 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 1.1 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 4.4 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.5 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.1 GO:0005592 collagen type XI trimer(GO:0005592)
0.0 1.1 GO:0043596 nuclear replication fork(GO:0043596)
0.0 0.9 GO:0031105 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0 0.8 GO:0098978 glutamatergic synapse(GO:0098978)
0.0 1.2 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.3 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 1.8 GO:0070160 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 1.0 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.1 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.0 1.2 GO:0030136 clathrin-coated vesicle(GO:0030136)
0.0 0.1 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 1.2 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 0.7 GO:0005776 autophagosome(GO:0005776)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.8 GO:0051059 NF-kappaB binding(GO:0051059)
0.4 1.5 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.3 1.0 GO:1902945 metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902945)
0.2 2.2 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.2 3.5 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.2 1.3 GO:0004376 glycolipid mannosyltransferase activity(GO:0004376)
0.2 1.5 GO:0010340 carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
0.1 0.4 GO:0004421 hydroxymethylglutaryl-CoA synthase activity(GO:0004421)
0.1 0.8 GO:0033192 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192)
0.1 1.5 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.1 1.4 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.1 1.8 GO:0008301 DNA binding, bending(GO:0008301)
0.1 0.7 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.1 1.1 GO:0016783 sulfurtransferase activity(GO:0016783)
0.1 0.6 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316)
0.1 1.0 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.1 0.4 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.1 1.0 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 0.9 GO:0004724 magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
0.1 1.0 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.1 1.2 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 4.0 GO:0003724 RNA helicase activity(GO:0003724)
0.0 0.9 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.0 0.3 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 0.4 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.0 0.1 GO:0055105 ubiquitin-protein transferase inhibitor activity(GO:0055105)
0.0 1.0 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 1.2 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.1 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.0 0.8 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.5 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.3 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.0 1.0 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 1.2 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 0.2 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 2.5 GO:0008081 phosphoric diester hydrolase activity(GO:0008081)
0.0 0.3 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 5.0 GO:0030246 carbohydrate binding(GO:0030246)
0.0 1.1 GO:0004520 endodeoxyribonuclease activity(GO:0004520)
0.0 3.3 GO:0060090 binding, bridging(GO:0060090)
0.0 0.4 GO:0010181 FMN binding(GO:0010181)
0.0 0.5 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0 0.3 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.9 GO:0005178 integrin binding(GO:0005178)
0.0 0.2 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.1 GO:0005522 profilin binding(GO:0005522)
0.0 0.3 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 1.2 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 0.8 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.8 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 1.1 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 0.4 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 1.8 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 0.3 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 0.9 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.1 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.4 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.2 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.2 0.8 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.1 1.2 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.1 0.9 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.1 1.3 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.1 1.7 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.1 0.9 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.1 0.9 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 0.6 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.1 0.6 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.1 0.4 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0 1.5 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.6 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.4 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 1.0 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.3 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.3 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.7 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.0 0.2 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.1 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.4 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 0.4 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.1 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.1 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.7 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis