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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for ddx28+nfatc1+nfatc2b+nfatc3a+nfatc3b+nfatc4

Z-value: 0.78

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Transcription factors associated with ddx28+nfatc1+nfatc2b+nfatc3a+nfatc3b+nfatc4

Gene Symbol Gene ID Gene Info
nfatc1
ENSDARG00000036168 nuclear factor of activated T cells 1
nfatc3b
ENSDARG00000051729 nuclear factor of activated T cells 3b
nfatc4
ENSDARG00000054162 nuclear factor of activated T cells 4
nfatc3a
ENSDARG00000076297 nuclear factor of activated T cells 3a
nfatc2b
ENSDARG00000079972 nuclear factor of activated T cells 2b
ddx28
ENSDARG00000112133 nuclear factor of activated T cells 3a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
nfatc3bdr11_v1_chr25_-_36248053_362480530.841.2e-05Click!
nfatc2bdr11_v1_chr6_-_55254786_552547860.832.2e-05Click!
nfatc1dr11_v1_chr19_+_22216778_222167780.744.3e-04Click!
nfatc3adr11_v1_chr7_-_34927961_34927961-0.409.8e-02Click!
nfatc4dr11_v1_chr2_-_37803614_37803614-0.243.4e-01Click!

Activity profile of ddx28+nfatc1+nfatc2b+nfatc3a+nfatc3b+nfatc4 motif

Sorted Z-values of ddx28+nfatc1+nfatc2b+nfatc3a+nfatc3b+nfatc4 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr5_-_29780752 2.03 ENSDART00000137400
ENSDART00000145021
cfap77
cilia and flagella associated protein 77
chr7_-_40110140 1.65 ENSDART00000173469
si:ch73-174h16.5
si:ch73-174h16.5
chr24_+_12690163 1.59 ENSDART00000100644
rec8b
REC8 meiotic recombination protein b
chr15_-_20933574 1.50 ENSDART00000152648
ENSDART00000152448
ENSDART00000152244
usp2a
ubiquitin specific peptidase 2a
chr5_-_51148298 1.49 ENSDART00000042420
ccdc180
coiled-coil domain containing 180
chr7_-_30367650 1.32 ENSDART00000075519
aldh1a2
aldehyde dehydrogenase 1 family, member A2
chr18_-_29961784 1.18 ENSDART00000135601
ENSDART00000140661
si:ch73-103b9.2
si:ch73-103b9.2
chr18_-_29962234 1.17 ENSDART00000144996
si:ch73-103b9.2
si:ch73-103b9.2
chr6_-_55254786 1.09 ENSDART00000113805
nfatc2b
nuclear factor of activated T cells 2b
chr19_-_41069573 1.06 ENSDART00000111982
ENSDART00000193142
sgce
sarcoglycan, epsilon
chr20_+_7209972 1.05 ENSDART00000189169
ENSDART00000136974
si:dkeyp-51f12.3
si:dkeyp-51f12.3
chr16_+_23397785 1.01 ENSDART00000148961
s100a10b
S100 calcium binding protein A10b
chr16_+_23398369 1.00 ENSDART00000037694
s100a10b
S100 calcium binding protein A10b
chr7_-_16597130 0.97 ENSDART00000144118
e2f8
E2F transcription factor 8
chr5_+_13353866 0.96 ENSDART00000099611
ccl19a.1
chemokine (C-C motif) ligand 19a, tandem duplicate 1
chr9_+_26103814 0.93 ENSDART00000026011
efnb2a
ephrin-B2a
chr12_-_31103187 0.91 ENSDART00000005562
ENSDART00000031408
ENSDART00000125046
ENSDART00000009237
ENSDART00000122972
ENSDART00000153068
tcf7l2
transcription factor 7 like 2
chr6_+_49095646 0.90 ENSDART00000103385
slc25a55a
solute carrier family 25, member 55a
chr4_-_9722568 0.89 ENSDART00000067190
tspan9b
tetraspanin 9b
chr6_-_39160422 0.87 ENSDART00000148661
stat2
signal transducer and activator of transcription 2
chr5_+_20112032 0.86 ENSDART00000130554
isg15
ISG15 ubiquitin-like modifier
chr12_+_46960579 0.86 ENSDART00000149032
oat
ornithine aminotransferase
chr20_-_48516765 0.85 ENSDART00000150200
si:zfos-223e1.2
si:zfos-223e1.2
chr16_-_13613475 0.84 ENSDART00000139102
dbpb
D site albumin promoter binding protein b
chr13_+_24717880 0.84 ENSDART00000147713
cfap43
cilia and flagella associated protein 43
chr4_+_7677318 0.84 ENSDART00000149218
elk3
ELK3, ETS-domain protein
chr7_-_16596938 0.80 ENSDART00000134548
e2f8
E2F transcription factor 8
chr6_-_39313027 0.80 ENSDART00000012644
krt4
keratin 4
chr6_-_8311044 0.79 ENSDART00000129674
slc44a2
solute carrier family 44 (choline transporter), member 2
chr3_-_20091964 0.77 ENSDART00000029386
ENSDART00000020253
ENSDART00000124326
slc4a1a
solute carrier family 4 (anion exchanger), member 1a (Diego blood group)
chr11_-_2469529 0.77 ENSDART00000125677
si:ch73-267c23.10
si:ch73-267c23.10
chr5_-_40910749 0.76 ENSDART00000083467
ENSDART00000133183
parp8
poly (ADP-ribose) polymerase family, member 8
chr8_+_25190023 0.76 ENSDART00000047528
gnai3
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3
chr3_-_20063671 0.75 ENSDART00000056614
ENSDART00000126915
ubtf
upstream binding transcription factor, RNA polymerase I
chr8_+_18615938 0.74 ENSDART00000089161
si:ch211-232d19.4
si:ch211-232d19.4
chr1_-_58592866 0.73 ENSDART00000161039
adgre5b.2
adhesion G protein-coupled receptor E5b, duplicate 2
chr7_+_34688527 0.73 ENSDART00000108473
plekhg4
pleckstrin homology domain containing, family G (with RhoGef domain) member 4
chr6_+_46258866 0.72 ENSDART00000134584
zgc:162324
zgc:162324
chr14_+_24277556 0.71 ENSDART00000122660
hnrnpa0a
heterogeneous nuclear ribonucleoprotein A0a
chr1_+_44003654 0.69 ENSDART00000131337
si:dkey-22i16.10
si:dkey-22i16.10
chr4_+_12013642 0.68 ENSDART00000067281
cry1aa
cryptochrome circadian clock 1aa
chr6_-_31576397 0.68 ENSDART00000111837
raver2
ribonucleoprotein, PTB-binding 2
chr22_+_38301365 0.66 ENSDART00000137339
traf5
Tnf receptor-associated factor 5
chr16_-_35585374 0.65 ENSDART00000180208
scmh1
Scm polycomb group protein homolog 1
chr15_+_36310442 0.65 ENSDART00000154678
gmnc
geminin coiled-coil domain containing
chr25_+_4837915 0.63 ENSDART00000168016
gnb5a
guanine nucleotide binding protein (G protein), beta 5a
chr23_+_23119008 0.62 ENSDART00000132418
samd11
sterile alpha motif domain containing 11
chr23_-_24682244 0.62 ENSDART00000104035
ctdsp2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
chr20_-_5369105 0.62 ENSDART00000114316
sptlc2b
serine palmitoyltransferase, long chain base subunit 2b
chr1_-_59415948 0.61 ENSDART00000168614
si:ch211-188p14.4
si:ch211-188p14.4
chr21_-_43131752 0.60 ENSDART00000024137
p4ha2
procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide 2
chr11_-_29623380 0.60 ENSDART00000162587
ENSDART00000193935
ENSDART00000191646
chd5
chromodomain helicase DNA binding protein 5
chr20_-_1176631 0.59 ENSDART00000152255
gabrr2b
gamma-aminobutyric acid (GABA) A receptor, rho 2b
chr23_-_27633730 0.59 ENSDART00000103639
arf3a
ADP-ribosylation factor 3a
chr7_-_40993456 0.58 ENSDART00000031700
en2a
engrailed homeobox 2a
chr14_-_33454595 0.58 ENSDART00000109615
ENSDART00000173267
ENSDART00000185737
ENSDART00000190989
tmem255a
transmembrane protein 255A
chr3_-_12026741 0.57 ENSDART00000132238
cfap70
cilia and flagella associated protein 70
chr6_-_57539141 0.57 ENSDART00000156967
itcha
itchy E3 ubiquitin protein ligase a
chr8_+_7144066 0.57 ENSDART00000146306
slc6a6a
solute carrier family 6 (neurotransmitter transporter), member 6a
chr1_-_56223913 0.56 ENSDART00000019573
zgc:65894
zgc:65894
chr8_+_40628926 0.55 ENSDART00000163598
dusp2
dual specificity phosphatase 2
chr4_-_15420452 0.53 ENSDART00000016230
plxna4
plexin A4
chr13_+_31497236 0.53 ENSDART00000146752
lrrc9
leucine rich repeat containing 9
chr2_-_24369087 0.53 ENSDART00000081237
plvapa
plasmalemma vesicle associated protein a
chr20_+_38276690 0.52 ENSDART00000061437
ccl38.6
chemokine (C-C motif) ligand 38, duplicate 6
chr7_-_52531252 0.51 ENSDART00000174369
tcf12
transcription factor 12
chr7_-_39738460 0.51 ENSDART00000052201
ccdc96
coiled-coil domain containing 96
chr5_-_68074592 0.51 ENSDART00000165052
ENSDART00000018792
spag7
sperm associated antigen 7
chr13_-_11967769 0.50 ENSDART00000158369
ARL3 (1 of many)
zgc:110197
chr10_-_28761454 0.50 ENSDART00000129400
alcama
activated leukocyte cell adhesion molecule a
chr11_-_34628789 0.49 ENSDART00000192433
mapkapk3
mitogen-activated protein kinase-activated protein kinase 3
chr23_-_18017946 0.49 ENSDART00000104592
pm20d1.2
peptidase M20 domain containing 1, tandem duplicate 2
chr11_+_13630107 0.49 ENSDART00000172220
si:ch211-1a19.3
si:ch211-1a19.3
chr6_-_40899618 0.49 ENSDART00000153949
ENSDART00000021969
zgc:172271
zgc:172271
chr9_+_3388099 0.48 ENSDART00000019910
dlx1a
distal-less homeobox 1a
chr25_-_15045338 0.48 ENSDART00000161165
ENSDART00000165774
ENSDART00000172538
pax6a
paired box 6a
chr19_+_9186175 0.48 ENSDART00000039325
hcn3
hyperpolarization activated cyclic nucleotide-gated potassium channel 3
chr11_-_11471857 0.48 ENSDART00000030103
krt94
keratin 94
chr4_-_1497384 0.48 ENSDART00000093236
zmp:0000000711
zmp:0000000711
chr9_+_31752628 0.48 ENSDART00000060054
itgbl1
integrin, beta-like 1
chr22_-_26353916 0.48 ENSDART00000077958
capn2b
calpain 2, (m/II) large subunit b
chr6_-_21091948 0.47 ENSDART00000057348
inha
inhibin, alpha
chr3_+_26734162 0.47 ENSDART00000114552
si:dkey-202l16.5
si:dkey-202l16.5
chr16_-_22713152 0.47 ENSDART00000140953
ENSDART00000143836
si:ch211-105c13.3
si:ch211-105c13.3
chr4_-_9764767 0.46 ENSDART00000164328
ENSDART00000147699
mical3b
microtubule associated monooxygenase, calponin and LIM domain containing 3b
chr11_-_18705303 0.46 ENSDART00000059732
id1
inhibitor of DNA binding 1
chr1_-_58664854 0.46 ENSDART00000109528
adgre5b.3
adhesion G protein-coupled receptor E5b, duplicate 3
chr12_+_17106117 0.45 ENSDART00000149990
acta2
actin, alpha 2, smooth muscle, aorta
chr3_-_39696066 0.45 ENSDART00000015393
b9d1
B9 protein domain 1
chr9_+_21243335 0.45 ENSDART00000114754
si:rp71-68n21.12
si:rp71-68n21.12
chr22_+_29027037 0.44 ENSDART00000170071
pimr97
Pim proto-oncogene, serine/threonine kinase, related 97
chr5_-_27994679 0.44 ENSDART00000132740
ppp3cca
protein phosphatase 3, catalytic subunit, gamma isozyme, a
chr13_-_40401870 0.44 ENSDART00000128951
nkx3.3
NK3 homeobox 3
chr23_-_20309505 0.43 ENSDART00000130856
lamb2l
laminin, beta 2-like
chr13_+_13681681 0.43 ENSDART00000057825
cfd
complement factor D (adipsin)
chr22_-_15587360 0.43 ENSDART00000142717
ENSDART00000138978
tpm4a
tropomyosin 4a
chr5_-_52813442 0.43 ENSDART00000169305
zgc:158260
zgc:158260
chr24_+_16149514 0.43 ENSDART00000152087
si:dkey-118j18.2
si:dkey-118j18.2
chr8_+_53464216 0.43 ENSDART00000169514
cacna1db
calcium channel, voltage-dependent, L type, alpha 1D subunit, b
chr1_-_47089818 0.41 ENSDART00000132378
itsn1
intersectin 1 (SH3 domain protein)
chr9_-_11263228 0.41 ENSDART00000113847
chpfa
chondroitin polymerizing factor a
chr24_-_17029374 0.41 ENSDART00000039267
ptgdsb.1
prostaglandin D2 synthase b, tandem duplicate 1
chr19_-_10243148 0.41 ENSDART00000148073
shisa7b
shisa family member 7
chr3_+_45687266 0.41 ENSDART00000131652
gpr146
G protein-coupled receptor 146
chr24_+_16149251 0.41 ENSDART00000188289
si:dkey-118j18.2
si:dkey-118j18.2
chr8_+_17078692 0.41 ENSDART00000023206
plk2b
polo-like kinase 2b (Drosophila)
chr25_-_12635371 0.40 ENSDART00000162463
zcchc14
zinc finger, CCHC domain containing 14
chr15_-_46821568 0.40 ENSDART00000148525
chrd
chordin
chr1_-_54425791 0.40 ENSDART00000039911
pkd1a
polycystic kidney disease 1a
chr13_+_35690023 0.40 ENSDART00000128865
ENSDART00000130050
psme4a
proteasome activator subunit 4a
chr3_+_52442102 0.39 ENSDART00000155455
si:ch211-191c10.1
si:ch211-191c10.1
chr7_-_52558495 0.39 ENSDART00000138263
ENSDART00000009938
ENSDART00000174292
ENSDART00000174218
ENSDART00000174335
tcf12
transcription factor 12
chr25_-_35524166 0.39 ENSDART00000156782
slc5a12
solute carrier family 5 (sodium/monocarboxylate cotransporter), member 12
chr2_+_21486529 0.38 ENSDART00000047468
inhbab
inhibin, beta Ab
chr19_-_11336782 0.38 ENSDART00000131014
sept7a
septin 7a
chr14_-_493029 0.38 ENSDART00000115093
zgc:172215
zgc:172215
chr8_+_22931427 0.38 ENSDART00000063096
sypa
synaptophysin a
chr21_+_11401247 0.38 ENSDART00000143952
cel.1
carboxyl ester lipase, tandem duplicate 1
chr14_-_4120636 0.37 ENSDART00000059230
irf2
interferon regulatory factor 2
chr19_-_4851411 0.37 ENSDART00000110398
fbxl20
F-box and leucine-rich repeat protein 20
chr10_+_33990572 0.37 ENSDART00000138547
fryb
furry homolog b (Drosophila)
chr12_-_5448993 0.37 ENSDART00000181802
tbc1d12b
TBC1 domain family, member 12b
chr5_+_51443009 0.37 ENSDART00000083350
rasgrf2b
Ras protein-specific guanine nucleotide-releasing factor 2b
chr5_+_37091626 0.37 ENSDART00000161054
tagln2
transgelin 2
chr7_-_26308098 0.37 ENSDART00000146440
ENSDART00000146935
ENSDART00000164627
zgc:77439
zgc:77439
chr4_+_23223881 0.36 ENSDART00000133056
ENSDART00000089126
trhde.1
thyrotropin releasing hormone degrading enzyme, tandem duplicate 1
chr17_+_28883353 0.36 ENSDART00000110322
prkd1
protein kinase D1
chr17_-_6518962 0.36 ENSDART00000176137
CR628323.3

chr13_-_8888334 0.36 ENSDART00000059881
plekhh2
pleckstrin homology domain containing, family H (with MyTH4 domain) member 2
chr10_+_44581378 0.35 ENSDART00000190331
sez6l
seizure related 6 homolog (mouse)-like
chr13_+_1155536 0.35 ENSDART00000148356
perp
PERP, TP53 apoptosis effector
chr22_+_26263290 0.35 ENSDART00000184840
BX649315.1

chr7_+_27059330 0.35 ENSDART00000173919
plekha7b
pleckstrin homology domain containing, family A member 7b
chr13_-_42749916 0.35 ENSDART00000140019
capn2a
calpain 2, (m/II) large subunit a
chr24_-_21819010 0.34 ENSDART00000091096
CR352265.1

chr25_-_7759453 0.34 ENSDART00000142439
ENSDART00000021577
phf21ab
PHD finger protein 21Ab
chr14_+_49296052 0.34 ENSDART00000006073
ENSDART00000105346
anxa6
annexin A6
chr21_-_26250443 0.34 ENSDART00000123713
gria1b
glutamate receptor, ionotropic, AMPA 1b
chr7_+_52761841 0.34 ENSDART00000111444
ppip5k1a
diphosphoinositol pentakisphosphate kinase 1a
chr11_-_37359416 0.34 ENSDART00000159184
erc2
ELKS/RAB6-interacting/CAST family member 2
chr3_-_39152478 0.34 ENSDART00000154550
si:dkeyp-57f11.2
si:dkeyp-57f11.2
chr25_+_4812685 0.34 ENSDART00000193103
myo5c
myosin VC
chr16_-_16225260 0.33 ENSDART00000165790
gra
granulito
chr5_-_18962794 0.33 ENSDART00000145210
ankle2
ankyrin repeat and LEM domain containing 2
chr19_+_5674907 0.33 ENSDART00000042189
pdk2b
pyruvate dehydrogenase kinase, isozyme 2b
chr13_+_23157053 0.33 ENSDART00000162359
sorbs1
sorbin and SH3 domain containing 1
chr21_-_17603182 0.33 ENSDART00000020048
ENSDART00000177270
gsna
gelsolin a
chr16_+_40301056 0.33 ENSDART00000058578
rspo3
R-spondin 3
chr7_+_18176162 0.32 ENSDART00000109171
rce1a
Ras converting CAAX endopeptidase 1a
chr21_+_11883336 0.32 ENSDART00000151757
dcaf12
DDB1 and CUL4 associated factor 12
chr19_+_19652439 0.32 ENSDART00000165934
hibadha
3-hydroxyisobutyrate dehydrogenase a
chr17_+_24848976 0.32 ENSDART00000062917
cx35.4
connexin 35.4
chr24_+_26887487 0.32 ENSDART00000189425
CR376848.1

chr9_-_12424791 0.32 ENSDART00000135447
ENSDART00000088199
zgc:162707
zgc:162707
chr12_-_19151708 0.31 ENSDART00000057124
tefa
thyrotrophic embryonic factor a
chr6_-_50204262 0.31 ENSDART00000163648
raly
RALY heterogeneous nuclear ribonucleoprotein
chr13_-_46991577 0.30 ENSDART00000114748
vip
vasoactive intestinal peptide
chr4_+_61995745 0.30 ENSDART00000171539
CT990567.1

chr2_-_22927958 0.30 ENSDART00000141621
myo7bb
myosin VIIBb
chr13_-_31470439 0.29 ENSDART00000076574
rtn1a
reticulon 1a
chr25_+_14087045 0.29 ENSDART00000155770
actc1c
actin, alpha, cardiac muscle 1c
chr25_+_35683956 0.29 ENSDART00000149768
kif21a
kinesin family member 21A
chr18_+_41495841 0.29 ENSDART00000098671
si:ch211-203b8.6
si:ch211-203b8.6
chr1_-_38816685 0.29 ENSDART00000075230
asb5b
ankyrin repeat and SOCS box containing 5b
chr7_-_13882988 0.29 ENSDART00000169828
rlbp1a
retinaldehyde binding protein 1a
chr13_-_50139916 0.28 ENSDART00000099475
nid1a
nidogen 1a
chr19_+_3056450 0.28 ENSDART00000141324
ENSDART00000082353
hsf1
heat shock transcription factor 1
chr14_+_26759332 0.27 ENSDART00000088484
ahnak
AHNAK nucleoprotein
chr9_-_8454060 0.27 ENSDART00000110158
irs2b
insulin receptor substrate 2b
chr14_-_30587814 0.27 ENSDART00000144912
ENSDART00000149714
tmem265
transmembrane protein 265
chr3_+_39099716 0.27 ENSDART00000083388
tmem98
transmembrane protein 98
chr6_-_40885496 0.27 ENSDART00000189857
sirt4
sirtuin 4
chr6_-_48094342 0.27 ENSDART00000137458
slc2a1b
solute carrier family 2 (facilitated glucose transporter), member 1b
chr16_-_30927454 0.27 ENSDART00000184015
slc45a4
solute carrier family 45, member 4
chr7_-_38658411 0.27 ENSDART00000109463
ENSDART00000017155
npsn
nephrosin
chr1_+_35790082 0.26 ENSDART00000085051
hhip
hedgehog interacting protein
chr6_-_36552844 0.26 ENSDART00000023613
her6
hairy-related 6
chr6_+_10450000 0.26 ENSDART00000151288
ENSDART00000187431
ENSDART00000192474
ENSDART00000188214
ENSDART00000184766
ENSDART00000190082
kcnh7
potassium channel, voltage gated eag related subfamily H, member 7
chr16_-_12787029 0.26 ENSDART00000139916
foxj2
forkhead box J2
chr22_+_17433968 0.25 ENSDART00000139523
rabgap1l
RAB GTPase activating protein 1-like
chr4_-_22311610 0.25 ENSDART00000137814
hcls1
hematopoietic cell-specific Lyn substrate 1
chr16_-_13004166 0.25 ENSDART00000133735
cacng7b
calcium channel, voltage-dependent, gamma subunit 7b
chr4_-_23643272 0.25 ENSDART00000112301
ENSDART00000133184
trhde.2
thyrotropin releasing hormone degrading enzyme, tandem duplicate 2
chr17_-_14700889 0.25 ENSDART00000179975
ptp4a2a
protein tyrosine phosphatase type IVA, member 2a
chr20_+_6142433 0.25 ENSDART00000054084
ENSDART00000136986
ttr
transthyretin (prealbumin, amyloidosis type I)
chr23_+_36130883 0.25 ENSDART00000103132
hoxc4a
homeobox C4a
chr9_+_13985567 0.25 ENSDART00000102296
cd28
CD28 molecule
chr2_-_32558795 0.24 ENSDART00000140026
smarcd3a
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3a
chr1_-_12278522 0.24 ENSDART00000142122
ENSDART00000003825
cplx2l
complexin 2, like
chr13_+_1575276 0.24 ENSDART00000165987
DST
dystonin
chr20_+_15552657 0.24 ENSDART00000063912
jun
Jun proto-oncogene, AP-1 transcription factor subunit
chr18_+_17663898 0.24 ENSDART00000021213
cpne2
copine II
chr3_-_26921475 0.24 ENSDART00000130281
ciita
class II, major histocompatibility complex, transactivator
chr12_+_18906939 0.24 ENSDART00000186074
josd1
Josephin domain containing 1
chr19_-_38611814 0.24 ENSDART00000151958
col16a1
collagen, type XVI, alpha 1
chr22_+_13886821 0.24 ENSDART00000130585
ENSDART00000105711
sh3bp4a
SH3-domain binding protein 4a
chr5_+_20922100 0.23 ENSDART00000131838
si:dkey-174n20.1
si:dkey-174n20.1
chr15_-_34845414 0.23 ENSDART00000009892
gabbr1a
gamma-aminobutyric acid (GABA) B receptor, 1a
chr17_-_25382367 0.23 ENSDART00000162306
ENSDART00000165282
lck
LCK proto-oncogene, Src family tyrosine kinase
chr5_-_48307804 0.23 ENSDART00000182831
ENSDART00000186920
ENSDART00000183585
mef2cb
myocyte enhancer factor 2cb

Network of associatons between targets according to the STRING database.

First level regulatory network of ddx28+nfatc1+nfatc2b+nfatc3a+nfatc3b+nfatc4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.8 GO:0033301 cell cycle comprising mitosis without cytokinesis(GO:0033301)
0.3 1.3 GO:0061113 pancreas morphogenesis(GO:0061113)
0.2 0.9 GO:0010226 response to lithium ion(GO:0010226)
0.2 0.8 GO:0015871 choline transport(GO:0015871)
0.2 0.9 GO:0007412 axon target recognition(GO:0007412)
0.2 0.5 GO:0007414 axonal defasciculation(GO:0007414)
0.2 0.5 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.2 1.6 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.2 0.5 GO:0090131 mesenchyme migration(GO:0090131)
0.1 0.6 GO:1903251 multi-ciliated epithelial cell differentiation(GO:1903251)
0.1 0.5 GO:2000275 regulation of oxidative phosphorylation uncoupler activity(GO:2000275)
0.1 0.8 GO:0007288 sperm axoneme assembly(GO:0007288)
0.1 0.3 GO:0080120 CAAX-box protein processing(GO:0071586) CAAX-box protein maturation(GO:0080120)
0.1 0.4 GO:0010712 regulation of collagen metabolic process(GO:0010712) regulation of collagen biosynthetic process(GO:0032965) regulation of multicellular organismal metabolic process(GO:0044246)
0.1 0.9 GO:0055129 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.1 0.7 GO:0046532 regulation of photoreceptor cell differentiation(GO:0046532)
0.1 0.9 GO:0015813 acidic amino acid transport(GO:0015800) aspartate transport(GO:0015810) L-glutamate transport(GO:0015813) malate-aspartate shuttle(GO:0043490)
0.1 0.3 GO:0001778 plasma membrane repair(GO:0001778) chondrocyte differentiation involved in endochondral bone morphogenesis(GO:0003413) growth plate cartilage chondrocyte differentiation(GO:0003418)
0.1 0.3 GO:0060829 negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060829)
0.1 0.4 GO:0010159 specification of organ position(GO:0010159)
0.1 0.2 GO:0006145 purine nucleobase catabolic process(GO:0006145)
0.1 0.2 GO:0061341 non-canonical Wnt signaling pathway involved in heart development(GO:0061341)
0.1 1.1 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.1 0.3 GO:0048242 copulation(GO:0007620) regulation of epinephrine secretion(GO:0014060) positive regulation of epinephrine secretion(GO:0032812) positive regulation of catecholamine secretion(GO:0033605) penile erection(GO:0043084) epinephrine transport(GO:0048241) epinephrine secretion(GO:0048242) regulation of penile erection(GO:0060405) positive regulation of penile erection(GO:0060406) prolactin secretion(GO:0070459)
0.1 0.9 GO:0060561 apoptotic process involved in morphogenesis(GO:0060561)
0.1 0.2 GO:0046099 guanine salvage(GO:0006178) GMP salvage(GO:0032263) guanine metabolic process(GO:0046098) guanine biosynthetic process(GO:0046099)
0.1 0.5 GO:0060221 retinal rod cell differentiation(GO:0060221)
0.1 0.2 GO:0045579 positive regulation of B cell differentiation(GO:0045579)
0.1 0.9 GO:0071357 response to type I interferon(GO:0034340) type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.1 0.4 GO:0035093 spermatid nucleus differentiation(GO:0007289) sperm chromatin condensation(GO:0035092) spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.1 0.4 GO:1901490 regulation of lymphangiogenesis(GO:1901490)
0.1 0.2 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.1 0.2 GO:0070914 UV-damage excision repair(GO:0070914)
0.1 0.6 GO:0034312 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.1 0.3 GO:0006574 valine catabolic process(GO:0006574)
0.0 0.5 GO:0048790 maintenance of presynaptic active zone structure(GO:0048790) maintenance of synapse structure(GO:0099558)
0.0 0.2 GO:0006844 acyl carnitine transport(GO:0006844)
0.0 0.4 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.8 GO:0006658 phosphatidylserine metabolic process(GO:0006658)
0.0 0.1 GO:0002839 response to tumor cell(GO:0002347) natural killer cell cytokine production(GO:0002370) immune response to tumor cell(GO:0002418) natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002420) natural killer cell mediated immune response to tumor cell(GO:0002423) regulation of natural killer cell cytokine production(GO:0002727) positive regulation of natural killer cell cytokine production(GO:0002729) positive regulation of response to biotic stimulus(GO:0002833) regulation of response to tumor cell(GO:0002834) positive regulation of response to tumor cell(GO:0002836) regulation of immune response to tumor cell(GO:0002837) positive regulation of immune response to tumor cell(GO:0002839) regulation of natural killer cell mediated immune response to tumor cell(GO:0002855) positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002858) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860) positive regulation of mast cell activation(GO:0033005) positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369)
0.0 0.6 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 1.0 GO:0007634 optokinetic behavior(GO:0007634)
0.0 0.3 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.0 0.2 GO:0071908 determination of intestine left/right asymmetry(GO:0071908)
0.0 0.2 GO:0071881 adenylate cyclase-inhibiting adrenergic receptor signaling pathway(GO:0071881)
0.0 1.4 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.0 0.4 GO:0097090 presynaptic membrane organization(GO:0097090) postsynaptic membrane assembly(GO:0097104) presynaptic membrane assembly(GO:0097105)
0.0 0.8 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.3 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.0 0.3 GO:0021794 thalamus development(GO:0021794)
0.0 0.2 GO:0030908 intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908)
0.0 0.6 GO:0019471 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471)
0.0 0.1 GO:0070166 enamel mineralization(GO:0070166)
0.0 0.3 GO:0048635 negative regulation of muscle organ development(GO:0048635)
0.0 0.1 GO:0061010 gall bladder development(GO:0061010)
0.0 1.0 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.0 0.2 GO:0032986 nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.0 0.4 GO:2000785 regulation of autophagosome assembly(GO:2000785)
0.0 0.3 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.1 GO:0061549 sympathetic ganglion development(GO:0061549)
0.0 0.1 GO:0002312 B cell activation involved in immune response(GO:0002312) isotype switching(GO:0045190)
0.0 0.2 GO:0072337 modified amino acid transport(GO:0072337)
0.0 0.5 GO:0007622 rhythmic behavior(GO:0007622) circadian behavior(GO:0048512)
0.0 0.1 GO:0001773 myeloid dendritic cell activation(GO:0001773) myeloid dendritic cell differentiation(GO:0043011)
0.0 0.1 GO:0006699 bile acid biosynthetic process(GO:0006699) bile acid metabolic process(GO:0008206)
0.0 0.2 GO:0051597 response to methylmercury(GO:0051597)
0.0 1.0 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.0 0.6 GO:0072348 sulfur compound transport(GO:0072348)
0.0 0.1 GO:0010799 regulation of peptidyl-threonine phosphorylation(GO:0010799) negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.0 0.1 GO:1903798 regulation of production of small RNA involved in gene silencing by RNA(GO:0070920) regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903798)
0.0 0.4 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.0 0.1 GO:0090243 fibroblast growth factor receptor signaling pathway involved in somitogenesis(GO:0090243)
0.0 0.2 GO:0002260 lymphocyte homeostasis(GO:0002260)
0.0 0.4 GO:0042752 regulation of circadian rhythm(GO:0042752)
0.0 0.2 GO:0007190 activation of adenylate cyclase activity(GO:0007190) positive regulation of cAMP metabolic process(GO:0030816) positive regulation of cAMP biosynthetic process(GO:0030819) positive regulation of adenylate cyclase activity(GO:0045762)
0.0 0.3 GO:0060324 face development(GO:0060324)
0.0 0.1 GO:0009826 unidimensional cell growth(GO:0009826)
0.0 0.2 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.0 0.4 GO:0070831 basement membrane assembly(GO:0070831)
0.0 0.1 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.0 0.5 GO:0043171 peptide catabolic process(GO:0043171)
0.0 0.2 GO:0009303 rRNA transcription(GO:0009303)
0.0 0.3 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.0 0.8 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.0 0.3 GO:0098943 neurotransmitter receptor transport, postsynaptic endosome to lysosome(GO:0098943)
0.0 0.2 GO:0016199 axon midline choice point recognition(GO:0016199)
0.0 0.1 GO:0070293 renal absorption(GO:0070293)
0.0 0.1 GO:0021982 pineal gland development(GO:0021982)
0.0 0.1 GO:0036075 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0 0.4 GO:0033627 cell adhesion mediated by integrin(GO:0033627)
0.0 0.1 GO:0010759 regulation of macrophage chemotaxis(GO:0010758) positive regulation of macrophage chemotaxis(GO:0010759) regulation of odontogenesis(GO:0042481) mononuclear cell migration(GO:0071674) regulation of mononuclear cell migration(GO:0071675)
0.0 0.0 GO:0061031 endodermal digestive tract morphogenesis(GO:0061031)
0.0 0.2 GO:0021772 olfactory bulb development(GO:0021772) olfactory lobe development(GO:0021988)
0.0 0.2 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.3 GO:0009408 response to heat(GO:0009408)
0.0 1.6 GO:0016579 protein deubiquitination(GO:0016579)
0.0 0.0 GO:0019242 methylglyoxal biosynthetic process(GO:0019242) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.0 0.2 GO:0035278 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.0 0.4 GO:0046330 positive regulation of JNK cascade(GO:0046330)
0.0 0.4 GO:0060536 cartilage morphogenesis(GO:0060536)
0.0 0.4 GO:0032922 circadian regulation of gene expression(GO:0032922)
0.0 0.1 GO:0097066 response to thyroid hormone(GO:0097066)
0.0 0.3 GO:0051014 actin filament severing(GO:0051014)
0.0 0.3 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.0 0.2 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0 0.5 GO:0061512 protein localization to cilium(GO:0061512)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.2 1.6 GO:0034991 nuclear cohesin complex(GO:0000798) mitotic cohesin complex(GO:0030892) nuclear mitotic cohesin complex(GO:0034990) nuclear meiotic cohesin complex(GO:0034991)
0.2 1.1 GO:0016012 sarcoglycan complex(GO:0016012)
0.1 0.4 GO:1990111 spermatoproteasome complex(GO:1990111)
0.1 0.6 GO:0005955 calcineurin complex(GO:0005955)
0.1 0.8 GO:0045095 keratin filament(GO:0045095)
0.1 0.6 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.1 0.3 GO:0043034 costamere(GO:0043034)
0.0 0.2 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.0 0.1 GO:0044217 other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217) other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
0.0 0.5 GO:0071564 npBAF complex(GO:0071564)
0.0 0.2 GO:0038037 G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor heterodimeric complex(GO:0038039) G-protein coupled receptor complex(GO:0097648)
0.0 0.5 GO:0005869 dynactin complex(GO:0005869)
0.0 0.5 GO:0036038 MKS complex(GO:0036038)
0.0 1.2 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.5 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.1 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.2 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.0 0.4 GO:0043256 basal lamina(GO:0005605) laminin complex(GO:0043256)
0.0 0.5 GO:0048788 cytoskeleton of presynaptic active zone(GO:0048788)
0.0 0.6 GO:1902711 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.0 0.1 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.0 1.1 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.3 GO:0000813 ESCRT I complex(GO:0000813)
0.0 1.4 GO:0005930 axoneme(GO:0005930)
0.0 0.1 GO:0071914 prominosome(GO:0071914)
0.0 0.2 GO:0014704 intercalated disc(GO:0014704)
0.0 0.2 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0 0.3 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.4 GO:0043679 axon terminus(GO:0043679)
0.0 0.1 GO:0005688 U6 snRNP(GO:0005688)
0.0 0.3 GO:0043186 P granule(GO:0043186)
0.0 1.1 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 3.0 GO:0005929 cilium(GO:0005929)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.2 1.3 GO:0001130 bacterial-type RNA polymerase transcription factor activity, sequence-specific DNA binding(GO:0001130) bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding(GO:0001217)
0.1 0.4 GO:0004771 sterol esterase activity(GO:0004771)
0.1 0.5 GO:0015355 secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.1 0.6 GO:0033192 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192)
0.1 1.3 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.1 2.5 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.1 0.6 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1 0.3 GO:0000829 inositol heptakisphosphate kinase activity(GO:0000829) diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.1 0.3 GO:0008442 3-hydroxyisobutyrate dehydrogenase activity(GO:0008442)
0.1 0.5 GO:0008158 hedgehog receptor activity(GO:0008158)
0.1 0.9 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.1 0.2 GO:0004422 hypoxanthine phosphoribosyltransferase activity(GO:0004422)
0.1 0.6 GO:0008420 CTD phosphatase activity(GO:0008420)
0.1 0.2 GO:0070324 thyroid hormone binding(GO:0070324)
0.1 0.5 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.1 0.9 GO:0031386 protein tag(GO:0031386)
0.1 1.0 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.1 0.4 GO:0001972 retinoic acid binding(GO:0001972)
0.1 0.6 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656)
0.0 0.2 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697) type II activin receptor binding(GO:0070699)
0.0 0.3 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.4 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.0 0.2 GO:0015227 acyl carnitine transmembrane transporter activity(GO:0015227)
0.0 0.9 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.7 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
0.0 0.5 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.3 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 0.4 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.4 GO:0016504 peptidase activator activity(GO:0016504)
0.0 0.3 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 0.1 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.0 0.8 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.0 0.2 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.0 1.4 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.9 GO:0008483 transaminase activity(GO:0008483)
0.0 0.2 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 0.2 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
0.0 0.5 GO:0098882 structural constituent of presynaptic active zone(GO:0098882)
0.0 0.8 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.2 GO:0016725 oxidoreductase activity, acting on CH or CH2 groups(GO:0016725)
0.0 0.2 GO:0005113 patched binding(GO:0005113)
0.0 0.2 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.3 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.1 GO:0005153 interleukin-8 receptor binding(GO:0005153)
0.0 0.3 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 0.2 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.0 0.2 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.2 GO:0052812 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812)
0.0 0.5 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.6 GO:0016917 GABA-A receptor activity(GO:0004890) GABA receptor activity(GO:0016917)
0.0 0.6 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.6 GO:1901682 organic acid:sodium symporter activity(GO:0005343) sulfur compound transmembrane transporter activity(GO:1901682)
0.0 0.8 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.2 GO:0033613 activating transcription factor binding(GO:0033613)
0.0 0.6 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.8 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.4 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.5 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.4 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 0.2 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.1 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.2 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 0.1 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 1.6 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 0.0 GO:0008929 triose-phosphate isomerase activity(GO:0004807) methylglyoxal synthase activity(GO:0008929)
0.0 0.1 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.1 GO:1903924 estradiol binding(GO:1903924)
0.0 0.5 GO:0005272 sodium channel activity(GO:0005272)
0.0 0.1 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.1 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 0.2 GO:2001069 glycogen binding(GO:2001069)
0.0 0.3 GO:0004697 protein kinase C activity(GO:0004697) calcium-dependent protein kinase C activity(GO:0004698)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.1 0.8 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 0.6 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.1 PID IL23 PATHWAY IL23-mediated signaling events
0.0 0.5 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.5 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.2 PID IGF1 PATHWAY IGF1 pathway
0.0 0.5 PID IL3 PATHWAY IL3-mediated signaling events
0.0 0.4 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 0.5 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.7 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 0.5 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.2 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 0.2 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.3 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.6 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.3 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 0.8 PID AP1 PATHWAY AP-1 transcription factor network
0.0 0.3 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.1 PID S1P S1P2 PATHWAY S1P2 pathway
0.0 0.2 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.6 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 0.4 PID BMP PATHWAY BMP receptor signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.1 0.9 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.1 0.2 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.1 1.0 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.1 1.2 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.1 0.7 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.1 0.2 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.1 0.5 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.1 0.4 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.2 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.7 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.2 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.4 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.0 0.2 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.2 REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.0 0.9 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.1 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.3 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.2 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.2 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.2 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.4 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.6 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.4 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.8 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels