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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for dlx5a

Z-value: 0.22

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Transcription factors associated with dlx5a

Gene Symbol Gene ID Gene Info
dlx5a
ENSDARG00000042296 distal-less homeobox 5a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
dlx5adr11_v1_chr19_-_41472228_41472228-0.233.6e-01Click!

Activity profile of dlx5a motif

Sorted Z-values of dlx5a motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr16_-_42056137 0.42 ENSDART00000102798
zp3d.2
zona pellucida glycoprotein 3d tandem duplicate 2
chr2_+_6253246 0.39 ENSDART00000058256
ENSDART00000076700
zp3b
zona pellucida glycoprotein 3b
chr5_-_27867657 0.30 ENSDART00000112495
tcima
transcriptional and immune response regulator a
chr23_+_31913292 0.29 ENSDART00000136910
armc1l
armadillo repeat containing 1, like
chr23_+_31912882 0.26 ENSDART00000140505
armc1l
armadillo repeat containing 1, like
chr10_-_26512742 0.25 ENSDART00000135951
si:dkey-5g14.1
si:dkey-5g14.1
chr2_-_23004286 0.24 ENSDART00000134664
ENSDART00000110373
ENSDART00000185833
ENSDART00000187235
znf414
mllt1b
zinc finger protein 414
MLLT1, super elongation complex subunit b
chr10_+_19596214 0.23 ENSDART00000183110
CABZ01059626.1

chr1_-_13989643 0.23 ENSDART00000191046
elf2b
E74-like factor 2b (ets domain transcription factor)
chr10_-_26512993 0.22 ENSDART00000188549
ENSDART00000193316
si:dkey-5g14.1
si:dkey-5g14.1
chr19_+_15521997 0.19 ENSDART00000003164
ppp1r8a
protein phosphatase 1, regulatory subunit 8a
chr20_+_14114258 0.18 ENSDART00000044937
kcns3b
potassium voltage-gated channel, delayed-rectifier, subfamily S, member 3b
chr19_-_27336092 0.17 ENSDART00000176885
gtf2h4
general transcription factor IIH, polypeptide 4
chr19_-_28283844 0.17 ENSDART00000151756
ENSDART00000079104
ndufs6
NADH dehydrogenase (ubiquinone) Fe-S protein 6
chr3_+_17537352 0.15 ENSDART00000104549
hcrt
hypocretin (orexin) neuropeptide precursor
chr10_-_35149513 0.15 ENSDART00000063434
ENSDART00000131291
ripk4
receptor-interacting serine-threonine kinase 4
chr9_+_13229585 0.12 ENSDART00000154879
ENSDART00000141705
carf
calcium responsive transcription factor
chr20_-_47188966 0.11 ENSDART00000152965
si:dkeyp-104f11.9
si:dkeyp-104f11.9
chr23_+_44374041 0.10 ENSDART00000136056
ephb4b
eph receptor B4b
chr19_+_5480327 0.10 ENSDART00000148794
jupb
junction plakoglobin b
chr20_-_14114078 0.10 ENSDART00000168434
ENSDART00000104032
si:ch211-223m11.2
si:ch211-223m11.2
chr10_+_2529037 0.09 ENSDART00000123467
zmp:0000001301
zmp:0000001301
chr15_+_15856178 0.09 ENSDART00000080338
dusp14
dual specificity phosphatase 14
chr7_-_40110140 0.09 ENSDART00000173469
si:ch73-174h16.5
si:ch73-174h16.5
chr23_+_34990693 0.09 ENSDART00000013449
CHST13
si:ch211-236h17.3
chr20_+_39457598 0.08 ENSDART00000140931
ENSDART00000156176
pimr128
Pim proto-oncogene, serine/threonine kinase, related 128
chr1_-_53277413 0.08 ENSDART00000150579
znf330
zinc finger protein 330
chr20_+_46513651 0.08 ENSDART00000152977
zc3h14
zinc finger CCCH-type containing 14
chr19_-_205104 0.08 ENSDART00000011890
zbtb22a
zinc finger and BTB domain containing 22a
chr2_+_11205795 0.08 ENSDART00000019078
lhx8a
LIM homeobox 8a
chr16_+_54263921 0.08 ENSDART00000002856
drd2l
dopamine receptor D2 like
chr18_+_11970987 0.07 ENSDART00000144111
si:dkeyp-2c8.3
si:dkeyp-2c8.3
chr16_+_42471455 0.07 ENSDART00000166640
si:ch211-215k15.5
si:ch211-215k15.5
chr11_+_30057762 0.07 ENSDART00000164139
nhsb
Nance-Horan syndrome b (congenital cataracts and dental anomalies)
chr10_-_40968095 0.07 ENSDART00000184104
npffr1l1
neuropeptide FF receptor 1 like 1
chr12_+_1469090 0.06 ENSDART00000183637
usp22
ubiquitin specific peptidase 22
chr2_-_17694504 0.06 ENSDART00000133709
ptprfb
protein tyrosine phosphatase, receptor type, f, b
chr19_+_19512515 0.06 ENSDART00000180065
jazf1a
JAZF zinc finger 1a
chr4_-_63848305 0.05 ENSDART00000097308
BX901974.1

chr15_-_44512461 0.05 ENSDART00000155456
gria4a
glutamate receptor, ionotropic, AMPA 4a
chr4_-_11577253 0.05 ENSDART00000144452
net1
neuroepithelial cell transforming 1
chr3_-_23643751 0.05 ENSDART00000078425
ENSDART00000140264
eve1
even-skipped-like1
chr24_-_39637418 0.05 ENSDART00000142522
fam234a
family with sequence similarity 234, member A
chr7_+_69019851 0.04 ENSDART00000162891
CABZ01057488.1

chr21_+_6751405 0.04 ENSDART00000037265
ENSDART00000146371
olfm1b
olfactomedin 1b
chr19_+_712127 0.04 ENSDART00000093281
ENSDART00000180002
ENSDART00000146050
fhod3a
formin homology 2 domain containing 3a
chr1_-_17715493 0.04 ENSDART00000133027
si:dkey-256e7.8
si:dkey-256e7.8
chr5_+_66433287 0.04 ENSDART00000170757
kntc1
kinetochore associated 1
chr6_+_3680651 0.04 ENSDART00000013588
klhl41b
kelch-like family member 41b
chr21_+_6751760 0.04 ENSDART00000135914
olfm1b
olfactomedin 1b
chr9_-_49964810 0.04 ENSDART00000167098
scn1a
sodium channel, voltage-gated, type I, alpha
chr7_-_25895189 0.04 ENSDART00000173599
ENSDART00000079235
ENSDART00000173786
ENSDART00000173602
ENSDART00000079245
ENSDART00000187568
ENSDART00000173505
cd99l2
CD99 molecule-like 2
chr25_-_18953322 0.04 ENSDART00000155927
si:ch211-68a17.7
si:ch211-68a17.7
chr5_-_7829657 0.03 ENSDART00000158374
pdlim5a
PDZ and LIM domain 5a
chr4_+_306036 0.03 ENSDART00000103659
msgn1
mesogenin 1
chr6_-_6487876 0.03 ENSDART00000137642
cep170ab
centrosomal protein 170Ab
chr3_+_26019426 0.03 ENSDART00000135389
ENSDART00000182411
foxred2
FAD-dependent oxidoreductase domain containing 2
chr15_+_1796313 0.03 ENSDART00000126253
fam124b
family with sequence similarity 124B
chr15_-_31067589 0.03 ENSDART00000060157
lgals9l3
lectin, galactoside-binding, soluble, 9 (galectin 9)-like 3
chr16_-_31525290 0.03 ENSDART00000109996
wisp1b
WNT1 inducible signaling pathway protein 1b
chr19_+_4800549 0.03 ENSDART00000056235
st3gal1l
ST3 beta-galactoside alpha-2,3-sialyltransferase 1, like
chr16_+_45425181 0.03 ENSDART00000168591
phf1
PHD finger protein 1
chr8_-_27656765 0.02 ENSDART00000078491
mov10b.2
Moloney leukemia virus 10b, tandem duplicate 2
chr17_+_41343167 0.02 ENSDART00000156405
mocs1
molybdenum cofactor synthesis 1
chr20_-_2949028 0.02 ENSDART00000104667
ENSDART00000193151
ENSDART00000131946
cdk19
cyclin-dependent kinase 19
chr11_+_23760470 0.02 ENSDART00000175688
ENSDART00000121874
ENSDART00000086720
nfasca
neurofascin homolog (chicken) a
chr16_+_45424907 0.02 ENSDART00000134471
phf1
PHD finger protein 1
chr7_-_69647988 0.02 ENSDART00000169943
LO018231.1

chr25_-_34632050 0.02 ENSDART00000170671
megf8
multiple EGF-like-domains 8
chr23_+_40460333 0.02 ENSDART00000184658
soga3b
SOGA family member 3b
chr18_+_50461981 0.02 ENSDART00000158761
CU896640.1

chr24_-_31843173 0.02 ENSDART00000185782
steap2
STEAP family member 2, metalloreductase
chr2_+_38370535 0.02 ENSDART00000179614
psmb11a
proteasome subunit beta 11a
chr3_-_21397304 0.02 ENSDART00000189794
CT573446.1

chr3_-_46817499 0.02 ENSDART00000013717
elavl3
ELAV like neuron-specific RNA binding protein 3
chr17_-_20717845 0.01 ENSDART00000150037
ank3b
ankyrin 3b
chr2_-_10896745 0.01 ENSDART00000114609
cdcp2
CUB domain containing protein 2
chr18_+_43891051 0.01 ENSDART00000024213
cxcr5
chemokine (C-X-C motif) receptor 5
chr4_-_5795309 0.01 ENSDART00000039987
pgm3
phosphoglucomutase 3
chr7_+_29955368 0.01 ENSDART00000173686
tpma
alpha-tropomyosin
chr11_-_6188413 0.01 ENSDART00000109972
ccl44
chemokine (C-C motif) ligand 44
chr24_+_7336411 0.01 ENSDART00000191170
kmt2ca
lysine (K)-specific methyltransferase 2Ca
chr25_-_18913336 0.01 ENSDART00000171010
parietopsin
parietopsin
chr8_-_52413032 0.01 ENSDART00000183039
CABZ01070469.1

chr4_-_75681004 0.01 ENSDART00000186296
si:dkey-71l4.5
si:dkey-71l4.5
chr18_+_32444636 0.01 ENSDART00000164223
v2ra1
vomeronasal 2 receptor, a1
chr13_+_24829996 0.01 ENSDART00000147194
si:ch211-223p8.8
si:ch211-223p8.8
chr4_-_32466676 0.01 ENSDART00000193347
ENSDART00000169396
ENSDART00000145784
si:dkey-16p6.1
si:dkey-16p6.1
chr15_+_9053059 0.01 ENSDART00000012039
ppm1na
protein phosphatase, Mg2+/Mn2+ dependent, 1Na (putative)
chr4_-_32466449 0.01 ENSDART00000192050
si:dkey-16p6.1
si:dkey-16p6.1
chr5_-_30620625 0.00 ENSDART00000098273
tcnl
transcobalamin like
chr4_-_71152937 0.00 ENSDART00000191017
si:dkey-193i10.4
si:dkey-193i10.4
chr18_+_28106139 0.00 ENSDART00000089615
kiaa1549lb
KIAA1549-like b
chr22_-_6988102 0.00 ENSDART00000185618
fgfr1bl
fibroblast growth factor receptor 1b, like
chr4_-_71153608 0.00 ENSDART00000190144
ENSDART00000158406
si:dkey-193i10.4
si:dkey-193i10.4
chr19_-_5265155 0.00 ENSDART00000145003
prf1.3
perforin 1.3
chr16_+_31804590 0.00 ENSDART00000167321
wnt4b
wingless-type MMTV integration site family, member 4b
chr1_+_40199074 0.00 ENSDART00000179679
ENSDART00000136849
si:ch211-113e8.5
si:ch211-113e8.5

Network of associatons between targets according to the STRING database.

First level regulatory network of dlx5a

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 GO:2000344 binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.0 0.1 GO:0061400 positive regulation of transcription from RNA polymerase II promoter in response to calcium ion(GO:0061400)
0.0 0.2 GO:0042755 eating behavior(GO:0042755)
0.0 0.1 GO:0031441 negative regulation of mRNA 3'-end processing(GO:0031441) negative regulation of mRNA polyadenylation(GO:1900364)
0.0 0.1 GO:0002159 desmosome assembly(GO:0002159)
0.0 0.0 GO:0048340 paraxial mesoderm morphogenesis(GO:0048340) paraxial mesoderm formation(GO:0048341)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0000439 core TFIIH complex(GO:0000439)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 GO:0032190 acrosin binding(GO:0032190)
0.0 0.2 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.3 GO:0005112 Notch binding(GO:0005112)
0.0 0.1 GO:0045294 alpha-catenin binding(GO:0045294)