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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for drgx_arxb

Z-value: 0.33

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Transcription factors associated with drgx_arxb

Gene Symbol Gene ID Gene Info
drgx
ENSDARG00000069329 dorsal root ganglia homeobox
arxb
ENSDARG00000101523 aristaless related homeobox b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
drgxdr11_v1_chr13_+_30912117_30912117-0.905.0e-07Click!
arxbdr11_v1_chr21_-_40676224_40676224-0.872.1e-06Click!

Activity profile of drgx_arxb motif

Sorted Z-values of drgx_arxb motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr5_+_57924611 1.49 ENSDART00000050949
btg4
B-cell translocation gene 4
chr3_-_32337653 1.34 ENSDART00000156918
ENSDART00000156551
si:dkey-16p21.8
si:dkey-16p21.8
chr15_-_25099679 1.11 ENSDART00000154628
rflnb
refilin B
chr14_-_33481428 1.01 ENSDART00000147059
ENSDART00000140001
ENSDART00000124242
ENSDART00000164836
ENSDART00000190104
ENSDART00000186833
ENSDART00000180873
lamp2
lysosomal-associated membrane protein 2
chr17_-_30635298 0.88 ENSDART00000155478
sh3yl1
SH3 and SYLF domain containing 1
chr12_-_35386910 0.87 ENSDART00000153453
camk2g1
calcium/calmodulin-dependent protein kinase (CaM kinase) II gamma 1
chr1_-_18811517 0.85 ENSDART00000142026
si:dkey-167i21.2
si:dkey-167i21.2
chr15_-_25099233 0.84 ENSDART00000192617
rflnb
refilin B
chr2_-_38284648 0.75 ENSDART00000148281
ENSDART00000132621
si:ch211-14a17.7
si:ch211-14a17.7
chr19_-_25113660 0.72 ENSDART00000035538
ptp4a3
protein tyrosine phosphatase type IVA, member 3
chr20_-_20931197 0.68 ENSDART00000152726
btbd6b
BTB (POZ) domain containing 6b
chr23_-_36441693 0.68 ENSDART00000024354
csad
cysteine sulfinic acid decarboxylase
chr12_+_27232173 0.62 ENSDART00000193714
tmem106a
transmembrane protein 106A
chr11_-_3535537 0.59 ENSDART00000165329
ENSDART00000009788
ddx19
DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 19 (DBP5 homolog, yeast)
chr7_-_37895771 0.58 ENSDART00000084282
papd5
PAP associated domain containing 5
chr12_+_27231607 0.58 ENSDART00000066270
tmem106a
transmembrane protein 106A
chr18_-_13121983 0.56 ENSDART00000092648
rxylt1
ribitol xylosyltransferase 1
chr11_+_25693395 0.55 ENSDART00000110224
mon1bb
MON1 secretory trafficking family member Bb
chr2_-_47957673 0.55 ENSDART00000056305
fzd8b
frizzled class receptor 8b
chr24_+_21346796 0.54 ENSDART00000126519
shisa2b
shisa family member 2b
chr20_-_20930926 0.54 ENSDART00000123909
btbd6b
BTB (POZ) domain containing 6b
chr12_+_23850661 0.49 ENSDART00000152921
svila
supervillin a
chr15_+_22435460 0.49 ENSDART00000031976
tmem136a
transmembrane protein 136a
chr18_+_1703984 0.47 ENSDART00000114010
slitrk3a
SLIT and NTRK-like family, member 3a
chr10_+_40284003 0.47 ENSDART00000062795
ENSDART00000193825
ENSDART00000113582
git2b
G protein-coupled receptor kinase interacting ArfGAP 2b
chr15_+_25528290 0.46 ENSDART00000123143
npat
nuclear protein, ataxia-telangiectasia locus
chr15_-_17813680 0.46 ENSDART00000158556
CT573342.2

chr3_-_26787430 0.46 ENSDART00000087047
rab40c
RAB40c, member RAS oncogene family
chr1_-_40102836 0.44 ENSDART00000147317
cntf
ciliary neurotrophic factor
chr17_-_43863700 0.43 ENSDART00000157530
ahsa1b
AHA1, activator of heat shock protein ATPase homolog 1b
chr11_+_31380495 0.41 ENSDART00000185073
sipa1l2
signal-induced proliferation-associated 1 like 2
chr14_-_34605607 0.41 ENSDART00000191608
afap1l1a
actin filament associated protein 1-like 1a
chr17_-_31483469 0.39 ENSDART00000062907
ENSDART00000061547
ltk
leukocyte receptor tyrosine kinase
chr22_-_22337382 0.39 ENSDART00000144684
si:ch211-129c21.1
si:ch211-129c21.1
chr8_-_18203274 0.39 ENSDART00000134078
ENSDART00000180235
ENSDART00000080006
ENSDART00000125418
ENSDART00000142114
elovl8b
ELOVL fatty acid elongase 8b
chr16_-_39267185 0.36 ENSDART00000058550
ENSDART00000133642
gpd1l
glycerol-3-phosphate dehydrogenase 1 like
chr17_+_46387086 0.33 ENSDART00000157079
si:dkey-206p8.1
si:dkey-206p8.1
chr21_-_27881752 0.33 ENSDART00000132583
nrxn2a
neurexin 2a
chr25_-_13381854 0.32 ENSDART00000164621
ENSDART00000169129
ndrg4
NDRG family member 4
chr17_+_28102487 0.29 ENSDART00000131638
ENSDART00000076265
zgc:91908
zgc:91908
chr6_-_10708960 0.29 ENSDART00000157704
si:dkey-34m19.3
si:dkey-34m19.3
chr14_-_34605804 0.29 ENSDART00000144547
afap1l1a
actin filament associated protein 1-like 1a
chr21_+_42717424 0.28 ENSDART00000166936
ENSDART00000172135
sh3pxd2b
SH3 and PX domains 2B
chr7_+_71764883 0.27 ENSDART00000166865
myl12.1
myosin, light chain 12, genome duplicate 1
chr15_+_12429206 0.27 ENSDART00000168997
tmprss4a
transmembrane protease, serine 4a
chr7_+_29167744 0.27 ENSDART00000076345
slc38a8b
solute carrier family 38, member 8b
chr9_+_29643036 0.26 ENSDART00000023210
ENSDART00000175160
trim13
tripartite motif containing 13
chr5_-_32489796 0.26 ENSDART00000168870
gpr107
G protein-coupled receptor 107
chr5_-_69180587 0.24 ENSDART00000156681
ENSDART00000160753
zgc:171967
zgc:171967
chr25_+_31276842 0.24 ENSDART00000187238
tnni2a.4
troponin I type 2a (skeletal, fast), tandem duplicate 4
chr2_+_37227011 0.24 ENSDART00000126587
ENSDART00000084958
samd7
sterile alpha motif domain containing 7
chr12_-_47601845 0.23 ENSDART00000169548
ENSDART00000182889
rgs7b
regulator of G protein signaling 7b
chr18_+_3243292 0.23 ENSDART00000166580
pak1
p21 protein (Cdc42/Rac)-activated kinase 1
chr8_+_20393250 0.23 ENSDART00000015038
zap70
zeta chain of T cell receptor associated protein kinase 70
chr24_-_38079261 0.22 ENSDART00000105662
crp1
C-reactive protein 1
chr13_+_18507592 0.22 ENSDART00000142622
si:ch211-198a12.6
si:ch211-198a12.6
chr16_+_46410520 0.21 ENSDART00000131072
rpz2
rapunzel 2
chr5_-_69180227 0.21 ENSDART00000154816
zgc:171967
zgc:171967
chr13_+_39315881 0.20 ENSDART00000135999
si:dkey-85a20.4
si:dkey-85a20.4
chr8_-_43834442 0.20 ENSDART00000191927
adgrd1
adhesion G protein-coupled receptor D1
chr13_-_49444636 0.20 ENSDART00000136991
irf2bp2a
interferon regulatory factor 2 binding protein 2a
chr6_+_8315050 0.20 ENSDART00000189987
gcdha
glutaryl-CoA dehydrogenase a
chr13_-_25819825 0.20 ENSDART00000077612
rel
v-rel avian reticuloendotheliosis viral oncogene homolog
chr25_+_33002963 0.20 ENSDART00000187366
CABZ01046980.1

chr4_-_5775507 0.19 ENSDART00000021753
ccnc
cyclin C
chr8_+_23861461 0.19 ENSDART00000037109
srpk1a
SRSF protein kinase 1a
chr17_-_27382826 0.19 ENSDART00000186657
ENSDART00000155986
ENSDART00000191060
ENSDART00000077608
si:ch1073-358c10.1
si:ch1073-358c10.1
chr15_-_5720583 0.18 ENSDART00000158034
ENSDART00000190332
ENSDART00000109599
urb1
URB1 ribosome biogenesis 1 homolog (S. cerevisiae)
chr14_-_32631013 0.18 ENSDART00000176815
atp11c
ATPase phospholipid transporting 11C
chr2_-_26596794 0.17 ENSDART00000134685
ENSDART00000056787
zgc:113691
zgc:113691
chr9_+_36314867 0.17 ENSDART00000176763
lrp1bb
low density lipoprotein receptor-related protein 1Bb
chr20_+_39250673 0.17 ENSDART00000153003
reps1
RALBP1 associated Eps domain containing 1
chr7_+_47243564 0.17 ENSDART00000098942
ENSDART00000162237
znf507
zinc finger protein 507
chr13_-_29421331 0.15 ENSDART00000150228
chata
choline O-acetyltransferase a
chr5_+_6672870 0.14 ENSDART00000126598
pxna
paxillin a
chr25_-_19648154 0.14 ENSDART00000148570
atp2b1b
ATPase plasma membrane Ca2+ transporting 1b
chr6_+_16468776 0.13 ENSDART00000109151
ENSDART00000114667
zgc:161969
zgc:161969
chr9_-_21825913 0.13 ENSDART00000101986
mrpl30
mitochondrial ribosomal protein L30
chr17_+_21486047 0.13 ENSDART00000104608
pla2g4f.2
phospholipase A2, group IVF, tandem duplicate 2
chr18_-_17145111 0.13 ENSDART00000090446
zc3h18
zinc finger CCCH-type containing 18
chr6_+_39942417 0.12 ENSDART00000183256
itpr1a
inositol 1,4,5-trisphosphate receptor, type 1a
chr3_-_25268751 0.12 ENSDART00000139423
mgat3a
mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase a
chr17_-_1705013 0.12 ENSDART00000182864
CABZ01086293.1

chr22_+_39007533 0.12 ENSDART00000185958
ENSDART00000129848
fam208aa
family with sequence similarity 208, member Aa
chr3_+_3610140 0.12 ENSDART00000104977
pick1
protein interacting with prkca 1
chr11_+_31864921 0.11 ENSDART00000180252
diaph3
diaphanous-related formin 3
chr8_+_10001805 0.11 ENSDART00000132894
si:dkey-8e10.2
si:dkey-8e10.2
chr9_-_51436377 0.11 ENSDART00000006612
tbr1b
T-box, brain, 1b
chr20_-_28931901 0.11 ENSDART00000153082
ENSDART00000046042
susd6
sushi domain containing 6
chr13_-_31017960 0.11 ENSDART00000145287
wdfy4
WDFY family member 4
chr8_+_50953776 0.11 ENSDART00000013870
zgc:56596
zgc:56596
chr8_-_43847138 0.11 ENSDART00000148358
adgrd1
adhesion G protein-coupled receptor D1
chr13_+_15581270 0.10 ENSDART00000189880
ENSDART00000190067
ENSDART00000041293
mark3a
MAP/microtubule affinity-regulating kinase 3a
chr21_-_18262287 0.10 ENSDART00000176716
vav2
vav 2 guanine nucleotide exchange factor
chr5_+_61361815 0.10 ENSDART00000009507
gatsl2
GATS protein-like 2
chr8_-_38406831 0.09 ENSDART00000112991
ENSDART00000191445
sorbs3
sorbin and SH3 domain containing 3
chr11_+_36409457 0.09 ENSDART00000077641
cyb561d1
cytochrome b561 family, member D1
chr23_+_25135858 0.09 ENSDART00000103986
fam3a
family with sequence similarity 3, member A
chr3_-_31069776 0.08 ENSDART00000167462
elob
elongin B
chr6_+_40832635 0.08 ENSDART00000011931
ruvbl1
RuvB-like AAA ATPase 1
chr6_+_58698475 0.08 ENSDART00000056138
igsf8
immunoglobulin superfamily, member 8
chr23_-_18130264 0.07 ENSDART00000016976
nucks1b
nuclear casein kinase and cyclin-dependent kinase substrate 1b
chr3_+_3852614 0.07 ENSDART00000184334
ENSDART00000162313
si:ch73-338o16.4
si:ch73-338o16.4
chr2_+_50967947 0.07 ENSDART00000162288
si:ch211-249o11.5
si:ch211-249o11.5
chr11_-_16115804 0.07 ENSDART00000143436
ENSDART00000157928
rpf1
ribosome production factor 1 homolog
chr1_-_999556 0.07 ENSDART00000170884
ENSDART00000172235
gart
phosphoribosylglycinamide formyltransferase
chr9_-_53537989 0.06 ENSDART00000114022
slitrk5b
SLIT and NTRK-like family, member 5b
chr13_-_50002852 0.06 ENSDART00000099439
lyst
lysosomal trafficking regulator
chr22_+_17433968 0.06 ENSDART00000139523
rabgap1l
RAB GTPase activating protein 1-like
chr1_-_23110740 0.06 ENSDART00000171848
ENSDART00000086797
ENSDART00000189344
ENSDART00000190858
adgrl3.1
adhesion G protein-coupled receptor L3.1
chr17_-_14726824 0.06 ENSDART00000162947
si:ch73-305o9.3
si:ch73-305o9.3
chr13_-_9091354 0.06 ENSDART00000140319
ENSDART00000142697
HTRA2 (1 of many)
si:dkey-112g5.13
chr5_-_18897482 0.05 ENSDART00000010101
ENSDART00000099434
aacs
acetoacetyl-CoA synthetase
chr14_+_22152060 0.05 ENSDART00000082697
ENSDART00000054982
gabra6a
gamma-aminobutyric acid (GABA) A receptor, alpha 6a
chr21_+_4313039 0.05 ENSDART00000141146
HTRA2 (1 of many)
si:dkey-84o3.4
chr13_-_9045879 0.05 ENSDART00000155463
ENSDART00000140041
ENSDART00000137454
si:dkey-112g5.11
si:dkey-112g5.11
chr17_-_12966907 0.05 ENSDART00000022874
psma6a
proteasome subunit alpha 6a
chr8_+_35212233 0.05 ENSDART00000111021
si:dkeyp-14d3.1
si:dkeyp-14d3.1
chr20_-_43775495 0.05 ENSDART00000100610
ENSDART00000149001
ENSDART00000148809
ENSDART00000100608
matn3a
matrilin 3a
chr10_-_40612773 0.04 ENSDART00000136685
ENSDART00000161373
taar16f
trace amine associated receptor 16f
chr10_-_40557210 0.04 ENSDART00000135297
taar18b
trace amine associated receptor 18b
chr12_-_34713888 0.04 ENSDART00000153272
bahcc1b
BAH domain and coiled-coil containing 1b
chr13_+_411607 0.04 ENSDART00000186483
CU570800.3

chr18_+_33468099 0.03 ENSDART00000131769
v2rh9
vomeronasal 2 receptor, h9
chr23_+_30967686 0.03 ENSDART00000144485
si:ch211-197l9.2
si:ch211-197l9.2
chr25_+_5755314 0.03 ENSDART00000172088
ENSDART00000164208
appl2
adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2
chr23_-_16484383 0.03 ENSDART00000187839
si:dkeyp-100a5.4
si:dkeyp-100a5.4
chr12_+_42436920 0.03 ENSDART00000177303
ebf3a
early B cell factor 3a
chr20_+_31287356 0.03 ENSDART00000007688
slc22a16
solute carrier family 22 (organic cation/carnitine transporter), member 16
chr2_-_20890429 0.03 ENSDART00000149989
pdca
phosducin a
chr21_-_10446405 0.03 ENSDART00000167948
hcn1
hyperpolarization activated cyclic nucleotide-gated potassium channel 1
chr14_-_41388178 0.03 ENSDART00000124532
ENSDART00000125016
ENSDART00000169247
cstf2
cleavage stimulation factor, 3' pre-RNA, subunit 2
chr20_+_41664350 0.03 ENSDART00000186247
fam184a
family with sequence similarity 184, member A
chr21_-_17482465 0.03 ENSDART00000004548
barhl1b
BarH-like homeobox 1b
chr18_+_33171765 0.03 ENSDART00000064153
si:ch73-125k17.2
si:ch73-125k17.2
chr10_-_1725699 0.02 ENSDART00000183555
gal3st1b
galactose-3-O-sulfotransferase 1b
chr15_+_31332552 0.02 ENSDART00000134933
ENSDART00000173915
or119-2
odorant receptor, family F, subfamily 119, member 2
chr24_-_38384432 0.02 ENSDART00000140739
lrrc4bb
leucine rich repeat containing 4Bb
chr5_+_11407504 0.02 ENSDART00000186723
ENSDART00000018047
zgc:112294
zgc:112294
chr14_-_17068511 0.02 ENSDART00000163766
phox2bb
paired-like homeobox 2bb
chr20_+_22130284 0.02 ENSDART00000025575
clocka
clock circadian regulator a
chr11_+_25539698 0.02 ENSDART00000035602
cxxc1b
CXXC finger protein 1b
chr5_-_7199998 0.02 ENSDART00000167316
CABZ01087502.1

chr5_-_58840971 0.02 ENSDART00000050932
tmem136b
transmembrane protein 136b
chr23_-_29553430 0.02 ENSDART00000157773
ENSDART00000126384
ube4b
ubiquitination factor E4B, UFD2 homolog (S. cerevisiae)
chr21_+_22237964 0.02 ENSDART00000003181
myo7ab
myosin VIIAb
chr17_+_18031304 0.01 ENSDART00000127259
setd3
SET domain containing 3
chr12_+_10631266 0.01 ENSDART00000161455
csf3a
colony stimulating factor 3 (granulocyte) a
chr10_-_40553066 0.01 ENSDART00000148118
ENSDART00000125958
taar18c
trace amine associated receptor 18c
chr14_-_17068712 0.01 ENSDART00000170277
phox2bb
paired-like homeobox 2bb
chr22_-_27113332 0.01 ENSDART00000146951
ENSDART00000178855
xpnpep1
X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
chr3_-_12970418 0.01 ENSDART00000158747
pdgfab
platelet-derived growth factor alpha polypeptide b
chr6_+_52938534 0.01 ENSDART00000174150
BX649282.2

chr22_-_15693085 0.01 ENSDART00000141861
si:ch1073-396h14.1
si:ch1073-396h14.1
chr21_+_21357309 0.01 ENSDART00000079634
ENSDART00000146102
kcnk12l
potassium channel, subfamily K, member 12 like
chr2_+_20605186 0.01 ENSDART00000128505
olfml2bb
olfactomedin-like 2Bb
chr2_+_49417900 0.01 ENSDART00000122742
ENSDART00000160783
rorcb
RAR-related orphan receptor C b
chr10_-_33621739 0.01 ENSDART00000142655
ENSDART00000128049
hunk
hormonally up-regulated Neu-associated kinase
chr15_+_45640906 0.01 ENSDART00000149361
ENSDART00000149079
sagb
S-antigen; retina and pineal gland (arrestin) b
chr5_+_40224938 0.01 ENSDART00000142897
si:dkey-193c22.2
si:dkey-193c22.2
chr3_+_32594357 0.01 ENSDART00000151639
unc119.2
unc-119 lipid binding chaperone B homolog 2
chr22_+_1821718 0.01 ENSDART00000132220
znf1002
zinc finger protein 1002
chr16_-_27640995 0.01 ENSDART00000019658
nacad
NAC alpha domain containing
chr21_-_44104600 0.01 ENSDART00000044599
oatx
organic anion transporter X
chr24_-_7697274 0.00 ENSDART00000186077
syt5b
synaptotagmin Vb
chr10_+_23537576 0.00 ENSDART00000130515
CR847844.1

chr6_+_23887314 0.00 ENSDART00000163188
znf648
zinc finger protein 648
chr12_+_42436328 0.00 ENSDART00000167324
ebf3a
early B cell factor 3a
chr10_+_4807913 0.00 ENSDART00000186099
palm2
paralemmin 2
chr17_-_45254585 0.00 ENSDART00000185507
ENSDART00000172080
ttbk2a
tau tubulin kinase 2a

Network of associatons between targets according to the STRING database.

First level regulatory network of drgx_arxb

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.0 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331) negative regulation of cartilage development(GO:0061037) negative regulation of chondrocyte development(GO:0061182) regulation of bone mineralization involved in bone maturation(GO:1900157) negative regulation of bone mineralization involved in bone maturation(GO:1900158) negative regulation of bone development(GO:1903011)
0.1 0.3 GO:0090004 positive regulation of Golgi to plasma membrane protein transport(GO:0042998) positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
0.1 1.0 GO:0006622 protein targeting to lysosome(GO:0006622)
0.1 0.4 GO:0006116 NADH oxidation(GO:0006116) glycerol-3-phosphate catabolic process(GO:0046168)
0.1 0.4 GO:0010693 regulation of alkaline phosphatase activity(GO:0010692) negative regulation of alkaline phosphatase activity(GO:0010693)
0.1 0.2 GO:0090069 regulation of ribosome biogenesis(GO:0090069)
0.1 1.2 GO:0006825 copper ion transport(GO:0006825)
0.1 0.4 GO:0070285 pigment cell development(GO:0070285)
0.1 0.5 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.1 GO:0008292 acetylcholine biosynthetic process(GO:0008292) acetate ester biosynthetic process(GO:1900620)
0.0 0.3 GO:0071800 podosome assembly(GO:0071800)
0.0 0.7 GO:0060046 binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.0 0.6 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.0 0.2 GO:0003232 bulbus arteriosus development(GO:0003232)
0.0 0.6 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 0.2 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 0.3 GO:0032781 positive regulation of ATPase activity(GO:0032781)
0.0 0.3 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.1 GO:0048260 positive regulation of receptor-mediated endocytosis(GO:0048260)
0.0 0.4 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.1 GO:0021877 forebrain neuron fate commitment(GO:0021877)
0.0 0.5 GO:0051014 actin filament severing(GO:0051014)
0.0 0.6 GO:0006623 protein targeting to vacuole(GO:0006623)
0.0 0.1 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.0 0.1 GO:0046083 adenine metabolic process(GO:0046083) adenine biosynthetic process(GO:0046084)
0.0 0.2 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.0 0.8 GO:0003146 heart jogging(GO:0003146)
0.0 1.5 GO:0008285 negative regulation of cell proliferation(GO:0008285)
0.0 0.1 GO:0060420 box C/D snoRNP assembly(GO:0000492) regulation of heart growth(GO:0060420)
0.0 0.1 GO:0071816 tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.0 0.4 GO:0043524 negative regulation of neuron apoptotic process(GO:0043524)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0031166 integral component of vacuolar membrane(GO:0031166) intrinsic component of vacuolar membrane(GO:0031310)
0.1 1.0 GO:0002102 podosome(GO:0002102)
0.1 0.4 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 1.3 GO:0031970 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.0 2.0 GO:0032432 actin filament bundle(GO:0032432)
0.0 0.1 GO:0098842 postsynaptic early endosome(GO:0098842)
0.0 0.9 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.1 GO:0097255 R2TP complex(GO:0097255)
0.0 0.6 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.1 GO:0071818 BAT3 complex(GO:0071818)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.0 GO:0031005 filamin binding(GO:0031005)
0.3 1.3 GO:0016531 copper chaperone activity(GO:0016531)
0.1 0.4 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.1 0.3 GO:0071253 connexin binding(GO:0071253)
0.0 0.2 GO:0004361 glutaryl-CoA dehydrogenase activity(GO:0004361)
0.0 0.7 GO:0032190 acrosin binding(GO:0032190)
0.0 0.6 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.3 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.4 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.3 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 0.4 GO:0102337 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.9 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.1 GO:0043139 5'-3' DNA helicase activity(GO:0043139)
0.0 0.7 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.2 GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
0.0 0.1 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.5 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.7 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.1 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.0 0.2 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.0 0.1 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.3 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 0.2 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 0.2 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.7 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.4 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 1.0 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+