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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for e2f2_e2f5

Z-value: 1.21

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Transcription factors associated with e2f2_e2f5

Gene Symbol Gene ID Gene Info
e2f2
ENSDARG00000079233 si_ch211-160f23.5
e2f5
ENSDARG00000038812 E2F transcription factor 5

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
e2f5dr11_v1_chr2_-_31686353_316864030.872.6e-06Click!
E2F2dr11_v1_chr17_-_27266053_272660530.691.4e-03Click!

Activity profile of e2f2_e2f5 motif

Sorted Z-values of e2f2_e2f5 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr22_-_4439311 2.90 ENSDART00000169317
uhrf1
ubiquitin-like with PHD and ring finger domains 1
chr3_-_54607166 2.78 ENSDART00000021977
dnmt1
DNA (cytosine-5-)-methyltransferase 1
chr8_-_1219815 2.73 ENSDART00000016800
ENSDART00000149969
znf367
zinc finger protein 367
chr11_-_11792766 2.39 ENSDART00000011657
cdc6
cell division cycle 6 homolog (S. cerevisiae)
chr21_-_27413294 2.25 ENSDART00000131646
slc29a2
solute carrier family 29 (equilibrative nucleoside transporter), member 2
chr2_-_29923630 2.10 ENSDART00000158844
ENSDART00000031130
paxip1
PAX interacting (with transcription-activation domain) protein 1
chr9_+_22780901 2.05 ENSDART00000110992
ENSDART00000143972
rif1
replication timing regulatory factor 1
chr2_-_29923403 2.01 ENSDART00000144672
paxip1
PAX interacting (with transcription-activation domain) protein 1
chr16_+_41015163 2.01 ENSDART00000058586
dek
DEK proto-oncogene
chr7_+_41812817 1.95 ENSDART00000174165
orc6
origin recognition complex, subunit 6
chr7_+_41812190 1.91 ENSDART00000113732
ENSDART00000174137
orc6
origin recognition complex, subunit 6
chr7_+_41812636 1.83 ENSDART00000174333
orc6
origin recognition complex, subunit 6
chr13_+_8255106 1.71 ENSDART00000080465
hells
helicase, lymphoid specific
chr2_+_44512324 1.64 ENSDART00000155017
ENSDART00000156310
ENSDART00000156686
pask
PAS domain containing serine/threonine kinase
chr16_+_41015781 1.60 ENSDART00000124543
dek
DEK proto-oncogene
chr6_+_33931740 1.57 ENSDART00000130492
ENSDART00000151213
orc1
origin recognition complex, subunit 1
chr8_-_4760723 1.53 ENSDART00000064201
cdc45
CDC45 cell division cycle 45 homolog (S. cerevisiae)
chr1_+_19538299 1.53 ENSDART00000109416
smc2
structural maintenance of chromosomes 2
chr23_-_36305874 1.46 ENSDART00000147598
ENSDART00000146986
ENSDART00000086985
ENSDART00000133259
cbx5
chromobox homolog 5 (HP1 alpha homolog, Drosophila)
chr19_-_47571797 1.45 ENSDART00000166180
ENSDART00000168134
rrm2
ribonucleotide reductase M2 polypeptide
chr25_-_35095129 1.45 ENSDART00000099866
ENSDART00000099868
kif15
kinesin family member 15
chr23_-_36306337 1.43 ENSDART00000142760
ENSDART00000136929
ENSDART00000143340
cbx5
chromobox homolog 5 (HP1 alpha homolog, Drosophila)
chr3_+_53116172 1.43 ENSDART00000115117
brd4
bromodomain containing 4
chr14_+_22129096 1.42 ENSDART00000132514
ccng1
cyclin G1
chr21_+_22558187 1.38 ENSDART00000167599
chek1
checkpoint kinase 1
chr14_-_49859747 1.38 ENSDART00000169456
ENSDART00000164967
nfkb1
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
chr23_+_36306539 1.37 ENSDART00000053267
hnrnpa1b
heterogeneous nuclear ribonucleoprotein A1b
chr6_-_34838397 1.36 ENSDART00000060169
ENSDART00000169605
mier1a
mesoderm induction early response 1a, transcriptional regulator
chr13_-_13030851 1.34 ENSDART00000009499
nsd2
nuclear receptor binding SET domain protein 2
chr3_+_26244353 1.34 ENSDART00000103733
atad5a
ATPase family, AAA domain containing 5a
chr17_+_25481466 1.33 ENSDART00000139451
aim1a
crystallin beta-gamma domain containing 1a
chr18_+_15271993 1.33 ENSDART00000099777
si:dkey-103i16.6
si:dkey-103i16.6
chr20_+_21268795 1.31 ENSDART00000090016
nudt14
nudix (nucleoside diphosphate linked moiety X)-type motif 14
chr2_+_37836821 1.29 ENSDART00000143203
parp2
poly (ADP-ribose) polymerase 2
chr22_-_3152357 1.29 ENSDART00000170983
lmnb2
lamin B2
chr6_-_32045951 1.28 ENSDART00000016629
ENSDART00000139055
efcab7
EF-hand calcium binding domain 7
chr7_+_55518519 1.27 ENSDART00000098476
ENSDART00000149915
cdt1
chromatin licensing and DNA replication factor 1
chr7_+_34236238 1.27 ENSDART00000052474
tipin
timeless interacting protein
chr19_-_2822372 1.22 ENSDART00000109130
ENSDART00000122385
recql4
RecQ helicase-like 4
chr5_+_12743640 1.17 ENSDART00000081411
pole
polymerase (DNA directed), epsilon
chr9_-_2892250 1.16 ENSDART00000140695
cdca7a
cell division cycle associated 7a
chr24_+_23840821 1.15 ENSDART00000128595
ENSDART00000127188
pola1
polymerase (DNA directed), alpha 1
chr5_+_34549365 1.11 ENSDART00000009500
aif1l
allograft inflammatory factor 1-like
chr11_+_18216404 1.11 ENSDART00000086437
tmcc1b
transmembrane and coiled-coil domain family 1b
chr20_+_38201644 1.09 ENSDART00000022694
ehd3
EH-domain containing 3
chr9_-_41351311 1.09 ENSDART00000145258
ENSDART00000139048
ENSDART00000024331
glsb
glutaminase b
chr8_+_53269657 1.08 ENSDART00000184212
gnb1a
guanine nucleotide binding protein (G protein), beta polypeptide 1a
chr19_-_10214264 1.08 ENSDART00000053300
ENSDART00000148225
znf865
zinc finger protein 865
chr20_-_9199721 1.06 ENSDART00000064140
ylpm1
YLP motif containing 1
chrM_+_6425 1.06 ENSDART00000093606
mt-co1
cytochrome c oxidase I, mitochondrial
chr21_+_233271 1.05 ENSDART00000171440
dtwd2
DTW domain containing 2
chr5_+_34549845 1.05 ENSDART00000139317
aif1l
allograft inflammatory factor 1-like
chr7_+_1550966 1.03 ENSDART00000177863
ENSDART00000126840
supt16h
SPT16 homolog, facilitates chromatin remodeling subunit
chr17_+_4325693 1.01 ENSDART00000154264
mcm8
minichromosome maintenance 8 homologous recombination repair factor
chr21_-_26490186 0.98 ENSDART00000009889
zgc:110540
zgc:110540
chr12_+_9499742 0.97 ENSDART00000044150
ENSDART00000136354
dnajc9
DnaJ (Hsp40) homolog, subfamily C, member 9
chr23_+_45339684 0.96 ENSDART00000149410
ENSDART00000102441
psip1b
PC4 and SFRS1 interacting protein 1b
chr3_-_34528306 0.93 ENSDART00000023039
sept9a
septin 9a
chr7_+_40658003 0.92 ENSDART00000172435
lmbr1
limb development membrane protein 1
chr12_+_9499993 0.91 ENSDART00000135871
dnajc9
DnaJ (Hsp40) homolog, subfamily C, member 9
chr5_-_65319387 0.88 ENSDART00000164649
col27a1b
collagen, type XXVII, alpha 1b
chr7_-_60351876 0.87 ENSDART00000098563
plcb3
phospholipase C, beta 3 (phosphatidylinositol-specific)
chr25_+_29688671 0.87 ENSDART00000073478
brd1b
bromodomain containing 1b
chr7_+_13527971 0.86 ENSDART00000020542
plekho2
pleckstrin homology domain containing, family O member 2
chr15_-_26538989 0.84 ENSDART00000032880
rpa1
replication protein A1
chr3_-_35865040 0.83 ENSDART00000102952
suz12a
SUZ12 polycomb repressive complex 2a subunit
chr22_-_5822147 0.81 ENSDART00000011076
cers5
ceramide synthase 5
chr8_-_25761544 0.80 ENSDART00000078152
suv39h1b
suppressor of variegation 3-9 homolog 1b
chr24_+_37338757 0.79 ENSDART00000182543
gnptg
N-acetylglucosamine-1-phosphate transferase, gamma subunit
chr2_-_57941037 0.79 ENSDART00000131420
si:dkeyp-68b7.5
si:dkeyp-68b7.5
chr9_-_12652984 0.78 ENSDART00000052256
sumo3b
small ubiquitin-like modifier 3b
chr17_-_22573311 0.77 ENSDART00000141523
ENSDART00000140022
ENSDART00000079390
ENSDART00000188644
exo1
exonuclease 1
chr3_+_22335030 0.77 ENSDART00000055676
zgc:103564
zgc:103564
chr25_-_4482449 0.74 ENSDART00000056278
ENSDART00000149425
slc25a22a
solute carrier family 25 member 22a
chr1_+_10305611 0.71 ENSDART00000043881
zgc:77880
zgc:77880
chr20_-_29498178 0.71 ENSDART00000152986
ENSDART00000027851
ENSDART00000152954
rrm2
ribonucleotide reductase M2 polypeptide
chr9_+_55455801 0.71 ENSDART00000144757
ENSDART00000186543
mxra5b
matrix-remodelling associated 5b
chr25_-_32363341 0.70 ENSDART00000153892
ENSDART00000114385
cep152
centrosomal protein 152
chr19_-_2582858 0.70 ENSDART00000113829
cdca7b
cell division cycle associated 7b
chr2_+_37837249 0.69 ENSDART00000113337
parp2
poly (ADP-ribose) polymerase 2
chr24_+_11908833 0.68 ENSDART00000178622
fen1
flap structure-specific endonuclease 1
chr20_-_38827623 0.68 ENSDART00000153310
cad
carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
chr19_-_47571456 0.68 ENSDART00000158071
ENSDART00000165841
rrm2
ribonucleotide reductase M2 polypeptide
chr5_-_42872712 0.66 ENSDART00000003947
flot2a
flotillin 2a
chr16_+_33143503 0.66 ENSDART00000058471
ENSDART00000179385
rhbdl2
rhomboid, veinlet-like 2 (Drosophila)
chr20_-_29499363 0.65 ENSDART00000152889
ENSDART00000153252
ENSDART00000170972
ENSDART00000166420
ENSDART00000163079
rrm2
ribonucleotide reductase M2 polypeptide
chr2_+_21000334 0.65 ENSDART00000062563
ENSDART00000147809
rreb1b
ras responsive element binding protein 1b
chr9_-_7213772 0.65 ENSDART00000174720
ENSDART00000092435
mgat4a
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
chr20_+_23947004 0.65 ENSDART00000144195
casp8ap2
caspase 8 associated protein 2
chr5_-_4923473 0.64 ENSDART00000134585
zbtb43
zinc finger and BTB domain containing 43
chr17_-_26537928 0.63 ENSDART00000155692
ENSDART00000122366
ccser2a
coiled-coil serine-rich protein 2a
chr14_-_31715373 0.63 ENSDART00000127303
ENSDART00000173274
ENSDART00000173435
ENSDART00000172876
ENSDART00000173036
map7d3
MAP7 domain containing 3
chr2_-_44344321 0.63 ENSDART00000084174
lig1
ligase I, DNA, ATP-dependent
chr12_+_9183626 0.62 ENSDART00000020192
tubgcp2
tubulin, gamma complex associated protein 2
chr13_-_36844945 0.62 ENSDART00000129562
ENSDART00000150899
nin
ninein (GSK3B interacting protein)
chr2_-_37134169 0.62 ENSDART00000146123
ENSDART00000146533
ENSDART00000040427
elavl1a
ELAV like RNA binding protein 1a
chr1_-_59313465 0.62 ENSDART00000158067
ENSDART00000159419
txndc11
thioredoxin domain containing 11
chr24_+_11908480 0.61 ENSDART00000024224
fen1
flap structure-specific endonuclease 1
chr18_+_41561285 0.59 ENSDART00000169621
baz1b
bromodomain adjacent to zinc finger domain, 1B
chr15_+_44184367 0.59 ENSDART00000162918
ENSDART00000110060
zgc:165514
zgc:165514
chr19_-_4137087 0.59 ENSDART00000164611
rragcb
Ras-related GTP binding Cb
chr22_+_1940595 0.59 ENSDART00000163506
znf1167
zinc finger protein 1167
chr24_+_10413484 0.59 ENSDART00000111014
myca
MYC proto-oncogene, bHLH transcription factor a
chr19_-_20777351 0.58 ENSDART00000019206
ngly1
N-glycanase 1
chr7_+_71586485 0.58 ENSDART00000165582
smchd1
structural maintenance of chromosomes flexible hinge domain containing 1
chr5_-_33255759 0.57 ENSDART00000085531
prkaa1
protein kinase, AMP-activated, alpha 1 catalytic subunit
chr12_-_33817114 0.56 ENSDART00000161265
twnk
twinkle mtDNA helicase
chr1_+_26677406 0.56 ENSDART00000183427
ENSDART00000180366
ENSDART00000181997
si:dkey-25o16.4
si:dkey-25o16.4
chr9_+_55379283 0.56 ENSDART00000192728
nlgn4b
neuroligin 4b
chr7_-_32629458 0.55 ENSDART00000001376
arl14ep
ADP-ribosylation factor-like 14 effector protein
chr2_-_57110477 0.55 ENSDART00000181132
slc25a42
solute carrier family 25, member 42
chr11_+_24339377 0.54 ENSDART00000133679
ENSDART00000135435
ENSDART00000017973
ENSDART00000131365
ENSDART00000186418
rbm39a
RNA binding motif protein 39a
chr18_+_41560822 0.54 ENSDART00000158503
baz1b
bromodomain adjacent to zinc finger domain, 1B
chr12_+_13344896 0.54 ENSDART00000089017
rnasen
ribonuclease type III, nuclear
chr9_-_2892045 0.53 ENSDART00000137201
cdca7a
cell division cycle associated 7a
chr7_+_71535045 0.53 ENSDART00000047069
tyms
thymidylate synthetase
chr1_+_26676758 0.52 ENSDART00000152299
si:dkey-25o16.4
si:dkey-25o16.4
chr16_-_35427060 0.52 ENSDART00000172294
ctps1b
CTP synthase 1b
chr6_-_25181012 0.51 ENSDART00000161585
lrrc8db
leucine rich repeat containing 8 VRAC subunit Db
chr19_+_9455218 0.51 ENSDART00000139385
si:ch211-288g17.3
si:ch211-288g17.3
chr24_-_40901410 0.51 ENSDART00000170688
wdr48a
WD repeat domain 48a
chr23_+_45025909 0.51 ENSDART00000188105
hmgb2b
high mobility group box 2b
chr7_+_24023653 0.50 ENSDART00000141165
tinf2
TERF1 (TRF1)-interacting nuclear factor 2
chr25_-_10629940 0.50 ENSDART00000154483
ENSDART00000155231
ppp6r3
protein phosphatase 6, regulatory subunit 3
chr15_+_44201056 0.50 ENSDART00000162433
ENSDART00000148336
CU655961.4

chr13_+_23282549 0.49 ENSDART00000101134
khdrbs2
KH domain containing, RNA binding, signal transduction associated 2
chr14_-_470505 0.49 ENSDART00000067147
ANKRD50
ankyrin repeat domain 50
chr7_-_69185124 0.49 ENSDART00000182217
ENSDART00000191359
usp10
ubiquitin specific peptidase 10
chr6_-_10740365 0.48 ENSDART00000150942
sp3b
Sp3b transcription factor
chr2_-_44777592 0.48 ENSDART00000113351
ENSDART00000169310
ncapd2
non-SMC condensin I complex, subunit D2
chr19_-_20403845 0.47 ENSDART00000151265
ENSDART00000147911
ENSDART00000151356
dazl
deleted in azoospermia-like
chr9_+_21536122 0.47 ENSDART00000182266
arhgef7a
Rho guanine nucleotide exchange factor (GEF) 7a
chr13_+_9612395 0.46 ENSDART00000136689
ENSDART00000138362
slf2
SMC5-SMC6 complex localization factor 2
chr19_-_31007417 0.46 ENSDART00000048144
rbbp4
retinoblastoma binding protein 4
chr22_+_12798569 0.46 ENSDART00000005720
stat1a
signal transducer and activator of transcription 1a
chr2_+_38055529 0.45 ENSDART00000145642
si:rp71-1g18.1
si:rp71-1g18.1
chr10_+_4046448 0.45 ENSDART00000123086
ENSDART00000052268
pitpnb
phosphatidylinositol transfer protein, beta
chr7_-_878473 0.45 ENSDART00000173567
si:cabz01080528.1
si:cabz01080528.1
chr14_-_5407118 0.44 ENSDART00000168074
pcgf1
polycomb group ring finger 1
chr4_-_15003854 0.44 ENSDART00000134701
ENSDART00000002401
klhdc10
kelch domain containing 10
chr9_+_21535885 0.44 ENSDART00000141408
arhgef7a
Rho guanine nucleotide exchange factor (GEF) 7a
chr21_-_40562705 0.43 ENSDART00000158289
ENSDART00000171997
taok1b
TAO kinase 1b
chr17_+_45737992 0.43 ENSDART00000135073
ENSDART00000143525
ENSDART00000158165
ENSDART00000184167
ENSDART00000109525
aspg
asparaginase homolog (S. cerevisiae)
chr5_-_54395488 0.43 ENSDART00000160781
zmynd19
zinc finger, MYND-type containing 19
chr3_-_18373604 0.43 ENSDART00000148132
spag9a
sperm associated antigen 9a
chr3_-_18373425 0.42 ENSDART00000178522
spag9a
sperm associated antigen 9a
chr1_+_14020445 0.42 ENSDART00000079716
hpf1
histone PARylation factor 1
chr19_-_6988837 0.42 ENSDART00000145741
ENSDART00000167640
znf384l
zinc finger protein 384 like
chr18_+_14329231 0.41 ENSDART00000151641
zgc:173742
zgc:173742
chr23_-_36449111 0.41 ENSDART00000110478
zgc:174906
zgc:174906
chr17_+_15674052 0.40 ENSDART00000156726
bach2a
BTB and CNC homology 1, basic leucine zipper transcription factor 2a
chr21_-_30032706 0.40 ENSDART00000156721
pwwp2a
PWWP domain containing 2A
chr22_-_10752471 0.39 ENSDART00000081191
sass6
SAS-6 centriolar assembly protein
chr22_-_20419660 0.39 ENSDART00000105520
pias4a
protein inhibitor of activated STAT, 4a
chr25_-_35599887 0.38 ENSDART00000153827
clpxb
caseinolytic mitochondrial matrix peptidase chaperone subunit b
chr1_+_27808916 0.38 ENSDART00000102335
pspc1
paraspeckle component 1
chr20_-_33487729 0.37 ENSDART00000061843
smek1
SMEK homolog 1, suppressor of mek1 (Dictyostelium)
chr18_-_30499489 0.37 ENSDART00000033746
gins2
GINS complex subunit 2
chr24_-_37338739 0.36 ENSDART00000146844
tsr3
TSR3, 20S rRNA accumulation, homolog (S. cerevisiae)
chr9_+_44721808 0.35 ENSDART00000190578
nckap1
NCK-associated protein 1
chr14_+_35023923 0.35 ENSDART00000172171
ebf3a
early B cell factor 3a
chr14_-_31814149 0.35 ENSDART00000173393
arhgef6
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr18_+_22174630 0.35 ENSDART00000089549
ripor1
RHO family interacting cell polarization regulator 1
chr20_+_41801913 0.35 ENSDART00000139805
mcm9
minichromosome maintenance 9 homologous recombination repair factor
chr8_-_22660678 0.34 ENSDART00000181258
iqsec2a
IQ motif and Sec7 domain 2a
chr8_-_17822259 0.34 ENSDART00000063587
st6galnac5b
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5b
chr18_-_33344 0.34 ENSDART00000129125
pde8a
phosphodiesterase 8A
chr7_-_7797654 0.34 ENSDART00000084503
ENSDART00000192779
ENSDART00000173079
trmt10b
tRNA methyltransferase 10B
chr18_-_46183462 0.33 ENSDART00000021192
kcnk6
potassium channel, subfamily K, member 6
chr2_-_4787566 0.33 ENSDART00000160663
ENSDART00000157808
tnk2b
tyrosine kinase, non-receptor, 2b
chr19_-_20403318 0.33 ENSDART00000136826
dazl
deleted in azoospermia-like
chr22_+_1947494 0.33 ENSDART00000159121
si:dkey-15h8.15
si:dkey-15h8.15
chr7_+_67748939 0.33 ENSDART00000162978
dhx38
DEAH (Asp-Glu-Ala-His) box polypeptide 38
chr20_+_43648369 0.33 ENSDART00000187930
ENSDART00000017269
parp1
poly (ADP-ribose) polymerase 1
chr20_-_10487951 0.32 ENSDART00000064112
glrx5
glutaredoxin 5 homolog (S. cerevisiae)
chr25_-_13659249 0.32 ENSDART00000045488
csnk2a2b
casein kinase 2, alpha prime polypeptide b
chr16_-_43335914 0.32 ENSDART00000111963
atad2
ATPase family, AAA domain containing 2
chr13_+_48358467 0.31 ENSDART00000171080
ENSDART00000162531
msh6
mutS homolog 6 (E. coli)
chr5_-_12743196 0.31 ENSDART00000188976
ENSDART00000137705
lztr1
leucine-zipper-like transcription regulator 1
chr16_-_37470042 0.31 ENSDART00000142916
si:ch211-208k15.1
si:ch211-208k15.1
chr4_+_18441988 0.31 ENSDART00000040827
ncaph2
non-SMC condensin II complex, subunit H2
chr2_-_33676494 0.30 ENSDART00000141192
b4galt2
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
chr8_-_12403077 0.30 ENSDART00000142150
phf19
PHD finger protein 19
chr3_+_45365098 0.30 ENSDART00000052746
ENSDART00000156555
ube2ia
ubiquitin-conjugating enzyme E2Ia
chr20_-_54245256 0.30 ENSDART00000170482
prpf39
PRP39 pre-mRNA processing factor 39 homolog (yeast)
chr15_-_1584137 0.30 ENSDART00000056772
trim59
tripartite motif containing 59
chr21_+_30721733 0.30 ENSDART00000040443
zgc:110224
zgc:110224
chr9_+_35014513 0.29 ENSDART00000100701
gabpa
GA binding protein transcription factor, alpha subunit
chr3_+_19245804 0.29 ENSDART00000134514
smarca4a
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4a
chr16_+_37891735 0.28 ENSDART00000178753
ENSDART00000142104
cep162
centrosomal protein 162
chr19_+_25465025 0.28 ENSDART00000018553
rpa3
replication protein A3
chr19_-_29294457 0.28 ENSDART00000130815
ENSDART00000103437
e2f3
E2F transcription factor 3
chr3_-_16110351 0.28 ENSDART00000064838
lasp1
LIM and SH3 protein 1
chr1_-_23110740 0.27 ENSDART00000171848
ENSDART00000086797
ENSDART00000189344
ENSDART00000190858
adgrl3.1
adhesion G protein-coupled receptor L3.1
chr21_-_19916021 0.27 ENSDART00000065671
eri1
exoribonuclease 1
chr17_+_26828027 0.27 ENSDART00000042060
jade1
jade family PHD finger 1
chr9_+_35014728 0.27 ENSDART00000100700
gabpa
GA binding protein transcription factor, alpha subunit
chr7_+_22809905 0.27 ENSDART00000166900
ENSDART00000143455
ENSDART00000126037
sf1
splicing factor 1
chr1_-_59216197 0.27 ENSDART00000062426
lpar2b
lysophosphatidic acid receptor 2b
chr7_+_19851422 0.27 ENSDART00000142970
ENSDART00000190027
mus81
MUS81 structure-specific endonuclease subunit

Network of associatons between targets according to the STRING database.

First level regulatory network of e2f2_e2f5

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 7.4 GO:0044030 regulation of DNA methylation(GO:0044030)
0.6 2.3 GO:0006272 leading strand elongation(GO:0006272)
0.5 4.0 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.5 1.4 GO:1901407 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407)
0.4 1.3 GO:0097676 histone H3-K36 dimethylation(GO:0097676)
0.4 2.3 GO:0015862 uridine transport(GO:0015862) pyrimidine nucleoside transport(GO:0015864)
0.4 4.0 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.4 2.5 GO:0000076 DNA replication checkpoint(GO:0000076)
0.3 1.9 GO:0033567 DNA replication, Okazaki fragment processing(GO:0033567)
0.3 1.1 GO:0015990 energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) electron transport coupled proton transport(GO:0015990)
0.2 0.7 GO:0021563 glossopharyngeal nerve development(GO:0021563)
0.2 1.1 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.2 0.6 GO:1903003 positive regulation of protein deubiquitination(GO:1903003)
0.2 1.6 GO:0070874 negative regulation of glycogen biosynthetic process(GO:0045719) negative regulation of glycogen metabolic process(GO:0070874)
0.2 0.8 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.2 2.3 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.2 1.5 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.1 0.7 GO:0098535 de novo centriole assembly(GO:0098535)
0.1 1.1 GO:0006543 glutamate biosynthetic process(GO:0006537) glutamine catabolic process(GO:0006543)
0.1 0.8 GO:0060965 negative regulation of posttranscriptional gene silencing(GO:0060149) negative regulation of gene silencing by miRNA(GO:0060965) negative regulation of gene silencing by RNA(GO:0060967)
0.1 0.5 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.1 0.6 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
0.1 1.2 GO:1902624 positive regulation of neutrophil migration(GO:1902624)
0.1 2.2 GO:0097178 ruffle assembly(GO:0097178)
0.1 0.3 GO:0006290 somatic diversification of immune receptors via somatic mutation(GO:0002566) pyrimidine dimer repair(GO:0006290) somatic hypermutation of immunoglobulin genes(GO:0016446)
0.1 0.8 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.1 0.5 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.1 5.9 GO:0032200 telomere maintenance(GO:0000723) telomere organization(GO:0032200)
0.1 3.6 GO:2000779 regulation of double-strand break repair(GO:2000779)
0.1 0.4 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.1 0.4 GO:0060049 regulation of protein glycosylation(GO:0060049)
0.1 0.7 GO:1904086 regulation of epiboly involved in gastrulation with mouth forming second(GO:1904086)
0.1 0.2 GO:0048478 replication fork protection(GO:0048478)
0.1 0.2 GO:0035751 regulation of lysosomal lumen pH(GO:0035751)
0.1 0.4 GO:0060339 negative regulation of type I interferon-mediated signaling pathway(GO:0060339)
0.1 0.3 GO:0045448 regulation of mitotic cell cycle, embryonic(GO:0009794) mitotic cell cycle, embryonic(GO:0045448)
0.1 0.3 GO:0036306 embryonic heart tube elongation(GO:0036306)
0.1 0.7 GO:0015810 acidic amino acid transport(GO:0015800) aspartate transport(GO:0015810) L-glutamate transport(GO:0015813) malate-aspartate shuttle(GO:0043490)
0.1 0.6 GO:0006264 mitochondrial DNA replication(GO:0006264)
0.1 0.3 GO:0090646 mitochondrial tRNA processing(GO:0090646)
0.1 0.5 GO:0071357 response to type I interferon(GO:0034340) type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.1 0.9 GO:0044154 histone H3-K14 acetylation(GO:0044154)
0.1 0.4 GO:0000455 enzyme-directed rRNA pseudouridine synthesis(GO:0000455)
0.1 0.3 GO:0000012 single strand break repair(GO:0000012)
0.1 0.6 GO:0006517 protein deglycosylation(GO:0006517)
0.1 0.4 GO:0040016 embryonic cleavage(GO:0040016)
0.1 1.0 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.1 0.2 GO:1905072 cardiac jelly development(GO:1905072)
0.0 0.3 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 1.0 GO:0006298 mismatch repair(GO:0006298)
0.0 0.9 GO:0043114 regulation of vascular permeability(GO:0043114)
0.0 1.7 GO:0048538 thymus development(GO:0048538)
0.0 0.1 GO:0030299 intestinal cholesterol absorption(GO:0030299)
0.0 0.2 GO:0060019 radial glial cell differentiation(GO:0060019)
0.0 1.4 GO:0030261 chromosome condensation(GO:0030261)
0.0 0.8 GO:0043507 activation of JUN kinase activity(GO:0007257) positive regulation of JUN kinase activity(GO:0043507)
0.0 0.3 GO:0031573 intra-S DNA damage checkpoint(GO:0031573)
0.0 0.2 GO:0046168 NADH oxidation(GO:0006116) glycerol-3-phosphate catabolic process(GO:0046168)
0.0 0.1 GO:0032776 DNA methylation on cytosine(GO:0032776)
0.0 0.3 GO:0021634 optic nerve formation(GO:0021634)
0.0 0.9 GO:0048570 notochord morphogenesis(GO:0048570)
0.0 0.4 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.0 0.6 GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625)
0.0 0.4 GO:0006265 DNA topological change(GO:0006265)
0.0 0.6 GO:0007020 microtubule nucleation(GO:0007020)
0.0 0.3 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.1 GO:0030219 megakaryocyte differentiation(GO:0030219)
0.0 1.3 GO:1904029 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.0 0.1 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 1.1 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.3 GO:0030719 P granule organization(GO:0030719)
0.0 1.4 GO:0016575 histone deacetylation(GO:0016575)
0.0 0.6 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.0 0.5 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0 0.7 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.1 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.0 0.2 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.0 0.4 GO:0097194 execution phase of apoptosis(GO:0097194)
0.0 0.3 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.3 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.0 0.3 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 0.8 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.0 0.5 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.0 0.3 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.0 5.3 GO:0060271 cilium morphogenesis(GO:0060271)
0.0 0.4 GO:0032874 positive regulation of stress-activated MAPK cascade(GO:0032874) positive regulation of stress-activated protein kinase signaling cascade(GO:0070304)
0.0 0.3 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.6 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 0.2 GO:0019985 translesion synthesis(GO:0019985)
0.0 0.2 GO:0035999 tetrahydrofolate interconversion(GO:0035999)
0.0 1.2 GO:0030516 regulation of axon extension(GO:0030516)
0.0 0.5 GO:0007006 mitochondrial membrane organization(GO:0007006)
0.0 0.9 GO:0061640 cytoskeleton-dependent cytokinesis(GO:0061640)
0.0 0.1 GO:0006167 AMP biosynthetic process(GO:0006167)
0.0 0.1 GO:0043981 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.0 0.1 GO:0030002 microglia differentiation(GO:0014004) cellular anion homeostasis(GO:0030002) cellular monovalent inorganic anion homeostasis(GO:0030320) cellular phosphate ion homeostasis(GO:0030643) cellular divalent inorganic anion homeostasis(GO:0072501) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0 0.1 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175) negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059) negative regulation of ERBB signaling pathway(GO:1901185)
0.0 0.1 GO:0031297 replication fork processing(GO:0031297)
0.0 0.2 GO:0030330 DNA damage response, signal transduction by p53 class mediator(GO:0030330)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 7.1 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.4 1.1 GO:0098536 deuterosome(GO:0098536)
0.3 1.9 GO:0031261 DNA replication preinitiation complex(GO:0031261)
0.3 1.2 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.3 1.3 GO:0031298 replication fork protection complex(GO:0031298)
0.2 1.1 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.2 0.6 GO:0008275 gamma-tubulin small complex(GO:0008275)
0.2 2.9 GO:0000792 heterochromatin(GO:0000792)
0.2 0.7 GO:0016600 flotillin complex(GO:0016600)
0.2 1.1 GO:0005662 DNA replication factor A complex(GO:0005662)
0.1 0.5 GO:0097268 cytoophidium(GO:0097268)
0.1 0.6 GO:1990131 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.1 1.0 GO:0035101 FACT complex(GO:0035101)
0.1 0.3 GO:0032301 MutSalpha complex(GO:0032301)
0.1 1.4 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 0.6 GO:0031258 lamellipodium membrane(GO:0031258)
0.1 0.3 GO:0033391 chromatoid body(GO:0033391)
0.1 1.1 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.1 2.6 GO:0000781 chromosome, telomeric region(GO:0000781)
0.1 0.3 GO:0005879 axonemal microtubule(GO:0005879)
0.1 0.6 GO:0097431 mitotic spindle pole(GO:0097431)
0.1 0.2 GO:0031429 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.0 1.1 GO:0060170 ciliary membrane(GO:0060170)
0.0 0.3 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.0 1.9 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.2 GO:0045293 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.0 0.3 GO:0000796 condensin complex(GO:0000796)
0.0 0.2 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.0 1.3 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 1.3 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 1.1 GO:0016605 PML body(GO:0016605)
0.0 0.9 GO:0032156 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0 0.2 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.3 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.0 0.3 GO:0000243 commitment complex(GO:0000243)
0.0 0.4 GO:0016363 nuclear matrix(GO:0016363)
0.0 2.2 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.2 GO:0043596 nuclear replication fork(GO:0043596)
0.0 1.2 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.2 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.2 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.3 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.1 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.0 1.1 GO:0005871 kinesin complex(GO:0005871)
0.0 1.2 GO:0030027 lamellipodium(GO:0030027)
0.0 0.6 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 3.2 GO:0005730 nucleolus(GO:0005730)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 3.5 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.3 1.3 GO:0070182 DNA polymerase binding(GO:0070182)
0.3 1.2 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.3 0.8 GO:0045145 single-stranded DNA 5'-3' exodeoxyribonuclease activity(GO:0045145)
0.2 0.7 GO:0016743 carboxyl- or carbamoyltransferase activity(GO:0016743)
0.2 2.9 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.2 0.6 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.2 2.3 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
0.2 1.3 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.2 0.5 GO:0080122 coenzyme A transmembrane transporter activity(GO:0015228) adenosine 3',5'-bisphosphate transmembrane transporter activity(GO:0071077) AMP transmembrane transporter activity(GO:0080122)
0.2 0.8 GO:0008432 JUN kinase binding(GO:0008432)
0.2 1.1 GO:0035173 histone kinase activity(GO:0035173)
0.1 1.0 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.1 1.2 GO:0009378 four-way junction helicase activity(GO:0009378)
0.1 0.5 GO:0003883 CTP synthase activity(GO:0003883)
0.1 1.1 GO:0004359 glutaminase activity(GO:0004359)
0.1 0.6 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.1 1.4 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.1 0.3 GO:0032143 guanine/thymine mispair binding(GO:0032137) single base insertion or deletion binding(GO:0032138) single thymine insertion binding(GO:0032143) oxidized DNA binding(GO:0032356) oxidized purine DNA binding(GO:0032357) mismatch repair complex binding(GO:0032404) MutLalpha complex binding(GO:0032405)
0.1 1.6 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.1 2.4 GO:0003688 DNA replication origin binding(GO:0003688)
0.1 0.8 GO:0008494 translation activator activity(GO:0008494)
0.1 0.8 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.1 1.3 GO:0070403 NAD+ binding(GO:0070403)
0.1 0.3 GO:0052905 tRNA (guanine(9)-N(1))-methyltransferase activity(GO:0052905)
0.1 1.2 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
0.1 0.8 GO:0098847 single-stranded telomeric DNA binding(GO:0043047) sequence-specific single stranded DNA binding(GO:0098847)
0.1 0.3 GO:0061656 SUMO conjugating enzyme activity(GO:0061656)
0.1 0.2 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.1 0.9 GO:0043994 H3 histone acetyltransferase activity(GO:0010484) histone acetyltransferase activity (H3-K23 specific)(GO:0043994)
0.1 2.3 GO:0035064 methylated histone binding(GO:0035064)
0.1 0.7 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.1 0.2 GO:0001734 mRNA (N6-adenosine)-methyltransferase activity(GO:0001734)
0.1 0.8 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.1 0.4 GO:0004067 asparaginase activity(GO:0004067)
0.1 0.3 GO:0003980 UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980)
0.1 1.4 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.1 0.4 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.8 GO:0031386 protein tag(GO:0031386)
0.0 0.3 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 0.0 GO:0032135 DNA insertion or deletion binding(GO:0032135)
0.0 0.6 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.3 GO:0048256 flap endonuclease activity(GO:0048256)
0.0 0.2 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.0 0.4 GO:1904047 S-adenosyl-L-methionine binding(GO:1904047)
0.0 1.8 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.0 0.4 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 0.5 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.4 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.2 GO:0000217 DNA secondary structure binding(GO:0000217)
0.0 1.8 GO:0031072 heat shock protein binding(GO:0031072)
0.0 4.6 GO:0042393 histone binding(GO:0042393)
0.0 0.1 GO:0015562 inositol hexakisphosphate binding(GO:0000822) efflux transmembrane transporter activity(GO:0015562)
0.0 0.2 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.0 0.2 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.0 0.5 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 0.9 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.0 0.5 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.8 GO:0003684 damaged DNA binding(GO:0003684)
0.0 0.1 GO:0015288 porin activity(GO:0015288)
0.0 1.3 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.2 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.1 GO:0047690 aspartyltransferase activity(GO:0047690)
0.0 0.3 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.0 0.3 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.5 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.5 GO:0015036 disulfide oxidoreductase activity(GO:0015036)
0.0 0.7 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.3 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.4 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.0 1.1 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.0 0.5 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.2 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.3 GO:0022840 leak channel activity(GO:0022840) potassium ion leak channel activity(GO:0022841) narrow pore channel activity(GO:0022842)
0.0 0.3 GO:0000339 RNA cap binding(GO:0000339)
0.0 0.3 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 0.6 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 0.3 GO:0008378 galactosyltransferase activity(GO:0008378)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.9 PID AURORA B PATHWAY Aurora B signaling
0.1 5.8 PID ATR PATHWAY ATR signaling pathway
0.1 0.6 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.1 5.7 PID E2F PATHWAY E2F transcription factor network
0.1 2.9 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.1 3.9 PID TELOMERASE PATHWAY Regulation of Telomerase
0.1 0.9 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 1.7 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 1.4 PID P53 REGULATION PATHWAY p53 pathway
0.0 1.6 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 1.4 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 0.6 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 0.6 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.7 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.0 0.4 PID CDC42 REG PATHWAY Regulation of CDC42 activity

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 10.8 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.4 8.0 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.2 2.4 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.1 1.1 REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.1 0.6 REACTOME LAGGING STRAND SYNTHESIS Genes involved in Lagging Strand Synthesis
0.1 0.9 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1 0.6 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.1 2.3 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.1 1.4 REACTOME KINESINS Genes involved in Kinesins
0.1 0.6 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.1 0.5 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.1 0.3 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.7 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 1.0 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.0 1.0 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.5 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.6 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.2 REACTOME TELOMERE MAINTENANCE Genes involved in Telomere Maintenance
0.0 2.1 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.8 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.4 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.3 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.3 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.1 REACTOME E2F MEDIATED REGULATION OF DNA REPLICATION Genes involved in E2F mediated regulation of DNA replication