Project

PRJNA438478: RNAseq of wild type zebrafish germline

Navigation
Downloads

Results for e2f4

Z-value: 0.44

Motif logo

logo of

Transcription factors associated with e2f4

Gene Symbol Gene ID Gene Info
e2f4
ENSDARG00000101578 E2F transcription factor 4
e2f4
ENSDARG00000109320 E2F transcription factor 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
e2f4dr11_v1_chr25_+_17405201_174052010.911.7e-07Click!

Activity profile of e2f4 motif

Sorted Z-values of e2f4 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr19_-_48391415 1.54 ENSDART00000170726
ENSDART00000169577
si:ch73-359m17.2
si:ch73-359m17.2
chr3_-_61592417 1.15 ENSDART00000155082
nptx2a
neuronal pentraxin 2a
chr16_-_32128345 0.81 ENSDART00000102100
ENSDART00000137699
cnot3a
CCR4-NOT transcription complex, subunit 3a
chr9_-_1703761 0.81 ENSDART00000144822
ENSDART00000137210
ENSDART00000135273
hnrnpa3
heterogeneous nuclear ribonucleoprotein A3
chr23_-_45568816 0.77 ENSDART00000076086
cyp17a2
cytochrome P450, family 17, subfamily A, polypeptide 2
chr25_-_774350 0.77 ENSDART00000166321
ENSDART00000160386
IRAK4
interleukin 1 receptor associated kinase 4
chr22_+_3153876 0.75 ENSDART00000163327
rpl36
ribosomal protein L36
chr3_+_22059066 0.75 ENSDART00000155739
kansl1b
KAT8 regulatory NSL complex subunit 1b
chr4_+_72742212 0.73 ENSDART00000171021
rab3ip
RAB3A interacting protein (rabin3)
chr16_+_54780544 0.72 ENSDART00000126646
si:zfos-1192g2.3
si:zfos-1192g2.3
chr24_+_21621654 0.64 ENSDART00000002595
rpl21
ribosomal protein L21
chr25_+_192116 0.63 ENSDART00000153983
zgc:114188
zgc:114188
chr7_+_24814866 0.53 ENSDART00000173581
si:ch211-226l4.6
si:ch211-226l4.6
chr25_-_35124576 0.49 ENSDART00000128017
zgc:171759
zgc:171759
chr18_+_17021391 0.41 ENSDART00000100160
chtf8
CTF8, chromosome transmission fidelity factor 8 homolog (S. cerevisiae)
chr25_+_35058088 0.41 ENSDART00000156838
zgc:112234
zgc:112234
chr25_+_35062353 0.39 ENSDART00000089844
zgc:113983
zgc:113983
chr4_-_17725008 0.39 ENSDART00000016658
chpt1
choline phosphotransferase 1
chr6_+_50381347 0.38 ENSDART00000055504
cyc1
cytochrome c-1
chr7_-_6345507 0.38 ENSDART00000173032
CU457819.4
Histone H3.2
chr7_-_6415991 0.37 ENSDART00000173349
CU457819.3
Histone H3.2
chr25_+_35067318 0.37 ENSDART00000186828
CU302436.1

chr17_+_43889371 0.34 ENSDART00000156871
ENSDART00000154702
msh4
mutS homolog 4
chr18_+_17020967 0.34 ENSDART00000189168
chtf8
CTF8, chromosome transmission fidelity factor 8 homolog (S. cerevisiae)
chr13_-_22907260 0.33 ENSDART00000143097
rufy2
RUN and FYVE domain containing 2
chr21_+_30355767 0.33 ENSDART00000189948
CR749164.1

chr4_+_3287819 0.31 ENSDART00000168633
CABZ01085700.1

chr3_-_16227683 0.29 ENSDART00000111707
cacnb1
calcium channel, voltage-dependent, beta 1 subunit
chr7_-_6459481 0.29 ENSDART00000173158
zgc:112234
zgc:112234
chr6_-_39653972 0.29 ENSDART00000155859
larp4ab
La ribonucleoprotein domain family, member 4Ab
chr7_-_6429031 0.27 ENSDART00000173413
zgc:112234
zgc:112234
chr7_-_6351021 0.26 ENSDART00000159542
zgc:112234
zgc:112234
chr2_-_37837056 0.24 ENSDART00000158179
ENSDART00000160317
ENSDART00000171409
mettl17
methyltransferase like 17
chr4_-_75175407 0.24 ENSDART00000180125
CABZ01043953.1

chr3_-_7897305 0.23 ENSDART00000169757
ubn2b
ubinuclein 2b
chr19_-_18855513 0.21 ENSDART00000162708
ppt2
palmitoyl-protein thioesterase 2
chr25_-_35109536 0.21 ENSDART00000185229
CU302436.5

chr14_+_94946 0.19 ENSDART00000165766
ENSDART00000163778
mcm7
minichromosome maintenance complex component 7
chr20_-_28433990 0.18 ENSDART00000182824
ENSDART00000193381
wdr21
WD repeat domain 21
chr24_+_17345521 0.18 ENSDART00000024722
ENSDART00000154250
ezh2
enhancer of zeste 2 polycomb repressive complex 2 subunit
chr24_+_7153628 0.17 ENSDART00000147715
si:dkeyp-101e12.1
si:dkeyp-101e12.1
chr7_+_34453185 0.17 ENSDART00000173875
ENSDART00000173921
ENSDART00000173995
si:cabz01009626.1
si:cabz01009626.1
chr3_-_7897563 0.17 ENSDART00000185232
ubn2b
ubinuclein 2b
chr19_-_18855717 0.16 ENSDART00000158192
ppt2
palmitoyl-protein thioesterase 2
chr7_-_73854476 0.16 ENSDART00000186481
zgc:173552
zgc:173552
chr10_+_406146 0.15 ENSDART00000145124
dact3a
dishevelled-binding antagonist of beta-catenin 3a
chr24_+_41690545 0.15 ENSDART00000160069
lama1
laminin, alpha 1
chr20_-_28433616 0.14 ENSDART00000169289
wdr21
WD repeat domain 21
chr10_-_37487612 0.14 ENSDART00000167964
ENSDART00000171326
si:dkey-65j4.2
si:dkey-65j4.2
chr10_+_21730585 0.12 ENSDART00000188576
pcdh1g22
protocadherin 1 gamma 22
chr25_+_35155676 0.12 ENSDART00000114598
zgc:112234
zgc:112234
chr25_+_35706493 0.12 ENSDART00000176741
kif21a
kinesin family member 21A
chr19_+_14921000 0.10 ENSDART00000144052
oprd1a
opioid receptor, delta 1a
chr20_+_35445462 0.09 ENSDART00000124497
tdrd6
tudor domain containing 6
chr10_+_6884123 0.09 ENSDART00000149095
ENSDART00000148772
ENSDART00000149334
ddx4
DEAD (Asp-Glu-Ala-Asp) box polypeptide 4
chr3_+_29641181 0.09 ENSDART00000151517
eif3d
eukaryotic translation initiation factor 3, subunit D
chr13_-_45942000 0.08 ENSDART00000158534
ENSDART00000171822
ENSDART00000166442
si:ch211-62a1.4
si:ch211-62a1.4
chr5_-_44496805 0.08 ENSDART00000110076
gas1a
growth arrest-specific 1a
chr20_+_28434196 0.07 ENSDART00000034245
dpf3
D4, zinc and double PHD fingers, family 3
chr6_-_425378 0.07 ENSDART00000192190
fam83fb
family with sequence similarity 83, member Fb
chr6_-_33978622 0.06 ENSDART00000151725
ENSDART00000124917
mpl
MPL proto-oncogene, thrombopoietin receptor
chr4_+_77740228 0.06 ENSDART00000193397
si:zfos-2131b9.2
si:zfos-2131b9.2
chr6_-_57722816 0.06 ENSDART00000186163
cbfa2t2
core-binding factor, runt domain, alpha subunit 2; translocated to, 2
chr17_+_21514777 0.05 ENSDART00000154633
chst15
carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
chr25_-_36370292 0.05 ENSDART00000152766
CR354435.1
Histone H2B 1/2
chr10_+_21789954 0.04 ENSDART00000157769
ENSDART00000171703
pcdh1gc5
protocadherin 1 gamma c 5
chr16_+_11834516 0.03 ENSDART00000146611
cxcr3.3
chemokine (C-X-C motif) receptor 3, tandem duplicate 3
chr14_-_52521460 0.03 ENSDART00000172110
GPR151
G protein-coupled receptor 151
chr7_+_57725708 0.03 ENSDART00000056466
ENSDART00000142259
ENSDART00000166198
camk2d1
calcium/calmodulin-dependent protein kinase (CaM kinase) II delta 1
chr3_+_58119571 0.03 ENSDART00000108979
si:ch211-256e16.4
si:ch211-256e16.4
chr17_-_50020672 0.01 ENSDART00000188942
filip1a
filamin A interacting protein 1a

Network of associatons between targets according to the STRING database.

First level regulatory network of e2f4

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0090069 regulation of ribosome biogenesis(GO:0090069)
0.1 0.8 GO:0008207 C21-steroid hormone metabolic process(GO:0008207)
0.1 0.8 GO:2000036 regulation of stem cell population maintenance(GO:2000036)
0.0 0.4 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0 0.2 GO:0070734 histone H3-K27 methylation(GO:0070734)
0.0 0.7 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 0.1 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.0 0.1 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.0 0.1 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.0 0.7 GO:0032402 melanosome transport(GO:0032402) pigment granule transport(GO:0051904)
0.0 0.2 GO:0036388 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.0 1.1 GO:0051966 regulation of synaptic transmission, glutamatergic(GO:0051966)
0.0 0.3 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.0 0.3 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.2 0.7 GO:0070319 Golgi to plasma membrane transport vesicle(GO:0070319)
0.1 0.8 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.1 0.8 GO:0044545 NSL complex(GO:0044545)
0.0 0.4 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.1 GO:0033391 chromatoid body(GO:0033391)
0.0 1.4 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.3 GO:0000795 synaptonemal complex(GO:0000795)
0.0 0.2 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.2 GO:0042555 MCM complex(GO:0042555)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.1 0.8 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.1 0.4 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.0 0.8 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.0 0.2 GO:1990518 ATP-dependent 3'-5' DNA helicase activity(GO:0043140) single-stranded DNA-dependent ATP-dependent 3'-5' DNA helicase activity(GO:1990518)
0.0 0.1 GO:0038046 enkephalin receptor activity(GO:0038046)
0.0 0.1 GO:0098808 mRNA cap binding(GO:0098808)
0.0 0.5 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.4 GO:0009055 electron carrier activity(GO:0009055)
0.0 2.0 GO:0003735 structural constituent of ribosome(GO:0003735)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.1 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 0.4 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.2 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 1.4 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation