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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for ebf3a-1+si:ch211-51e8.2

Z-value: 1.02

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Transcription factors associated with ebf3a-1+si:ch211-51e8.2

Gene Symbol Gene ID Gene Info
si_ch211-51e8.2
ENSDARG00000092635 si_ch211-51e8.2
ebf3a-1
ENSDARG00000099849 EBF transcription factor 1a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ebf3adr11_v1_chr14_+_35237613_352376130.165.2e-01Click!
EBF1 (1 of many)dr11_v1_chr21_-_33995213_33995213-0.019.6e-01Click!

Activity profile of ebf3a-1+si:ch211-51e8.2 motif

Sorted Z-values of ebf3a-1+si:ch211-51e8.2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr11_-_8208464 6.43 ENSDART00000161283
pimr203
Pim proto-oncogene, serine/threonine kinase, related 203
chr22_+_36914636 3.59 ENSDART00000150948
pimr205
Pim proto-oncogene, serine/threonine kinase, related 205
chr4_+_37992753 3.46 ENSDART00000193890
CR759843.2

chr6_-_8264751 2.68 ENSDART00000091628
ccdc151
coiled-coil domain containing 151
chr4_+_15819728 2.52 ENSDART00000101613
lrguk
leucine-rich repeats and guanylate kinase domain containing
chr18_-_21177674 2.38 ENSDART00000060175
si:dkey-12e7.4
si:dkey-12e7.4
chr11_-_8271374 2.36 ENSDART00000168253
pimr202
Pim proto-oncogene, serine/threonine kinase, related 202
chr14_-_858985 2.22 ENSDART00000148687
ENSDART00000149375
slc34a1a
solute carrier family 34 (type II sodium/phosphate cotransporter), member 1a
chr11_-_8288925 1.88 ENSDART00000168524
pimr202
Pim proto-oncogene, serine/threonine kinase, related 202
chr22_-_36934040 1.84 ENSDART00000151666
pimr206
Pim proto-oncogene, serine/threonine kinase, related 206
chr25_+_13157165 1.83 ENSDART00000155653
si:dkeyp-50b9.1
si:dkeyp-50b9.1
chr1_-_44701313 1.71 ENSDART00000193926
si:dkey-28b4.8
si:dkey-28b4.8
chr19_+_19786117 1.58 ENSDART00000167757
ENSDART00000163546
hoxa1a
homeobox A1a
chr22_-_18387059 1.50 ENSDART00000007769
tssk6
testis-specific serine kinase 6
chr9_+_44431174 1.50 ENSDART00000149726
ppp1r1c
protein phosphatase 1, regulatory (inhibitor) subunit 1C
chr1_-_59411901 1.44 ENSDART00000167015
si:ch211-188p14.4
si:ch211-188p14.4
chr3_-_3496738 1.42 ENSDART00000186849
CABZ01040998.1

chr25_+_4954220 1.41 ENSDART00000156034
si:ch73-265h17.2
si:ch73-265h17.2
chr3_+_26081343 1.37 ENSDART00000134647
atp2a1
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1
chr20_+_18209895 1.36 ENSDART00000111063
kctd1
potassium channel tetramerization domain containing 1
chr2_-_23541059 1.34 ENSDART00000133908
si:dkey-58b18.3
si:dkey-58b18.3
chr10_-_27199135 1.34 ENSDART00000189511
ENSDART00000180314
auts2a
autism susceptibility candidate 2a
chr6_-_43922813 1.31 ENSDART00000123341
prok2
prokineticin 2
chr21_-_11855828 1.28 ENSDART00000081666
ube2r2
ubiquitin-conjugating enzyme E2R 2
chr4_+_11375894 1.17 ENSDART00000190471
ENSDART00000143963
pcloa
piccolo presynaptic cytomatrix protein a
chr10_-_31563049 1.11 ENSDART00000023575
robo3
roundabout, axon guidance receptor, homolog 3 (Drosophila)
chr20_-_23439011 1.07 ENSDART00000022887
slc10a4
solute carrier family 10, member 4
chr15_+_37559570 1.02 ENSDART00000085522
hspb6
heat shock protein, alpha-crystallin-related, b6
chr19_+_58954 0.95 ENSDART00000162379
col14a1b
collagen, type XIV, alpha 1b
chr1_-_35924495 0.95 ENSDART00000184424
smad1
SMAD family member 1
chr9_-_22831836 0.94 ENSDART00000142585
neb
nebulin
chr8_+_30671060 0.94 ENSDART00000193749
adora2aa
adenosine A2a receptor a
chr7_+_25920792 0.92 ENSDART00000026295
arrb2b
arrestin, beta 2b
chr9_+_56443416 0.90 ENSDART00000167947
CABZ01079480.1

chr11_+_807153 0.89 ENSDART00000173289
vgll4b
vestigial-like family member 4b
chr20_+_46371458 0.87 ENSDART00000152912
adgrg11
adhesion G protein-coupled receptor G11
chr19_+_56351 0.87 ENSDART00000168334
col14a1b
collagen, type XIV, alpha 1b
chr24_+_3050020 0.85 ENSDART00000004241
inhbaa
inhibin, beta Aa
chr16_-_30927764 0.85 ENSDART00000156804
slc45a4
solute carrier family 45, member 4
chr23_-_33775145 0.84 ENSDART00000132147
ENSDART00000027959
ENSDART00000160116
racgap1
Rac GTPase activating protein 1
chr22_+_11756040 0.84 ENSDART00000105808
krt97
keratin 97
chr9_-_45149695 0.82 ENSDART00000162033
CU467837.1

chr12_+_34763795 0.81 ENSDART00000153097
slc38a10
solute carrier family 38, member 10
chr2_-_23603061 0.79 ENSDART00000132072
si:dkey-58b18.9
si:dkey-58b18.9
chr23_+_40460333 0.77 ENSDART00000184658
soga3b
SOGA family member 3b
chr1_-_17675037 0.76 ENSDART00000142689
si:dkey-256e7.5
si:dkey-256e7.5
chr13_+_12045758 0.75 ENSDART00000079398
ENSDART00000165467
ENSDART00000165880
gng2
guanine nucleotide binding protein (G protein), gamma 2
chr25_+_4541211 0.73 ENSDART00000129978
pnpla2
patatin-like phospholipase domain containing 2
chr5_-_38161033 0.72 ENSDART00000145907
gucy2d
guanylate cyclase 2D, retinal
chr24_-_31843173 0.69 ENSDART00000185782
steap2
STEAP family member 2, metalloreductase
chr14_-_21959712 0.69 ENSDART00000021417
p2rx3a
purinergic receptor P2X, ligand-gated ion channel, 3a
chr3_+_13559199 0.69 ENSDART00000166547
si:ch73-106n3.1
si:ch73-106n3.1
chr2_-_43123949 0.68 ENSDART00000075347
ENSDART00000132346
lrrc6
leucine rich repeat containing 6
chr8_-_34762163 0.67 ENSDART00000114080
setd1bb
SET domain containing 1B, b
chr12_-_33659328 0.66 ENSDART00000153457
tmem94
transmembrane protein 94
chr3_-_30158395 0.66 ENSDART00000103502
si:ch211-152f23.5
si:ch211-152f23.5
chr6_+_11850359 0.65 ENSDART00000109552
ENSDART00000188139
ENSDART00000181499
ENSDART00000178269
baz2ba
bromodomain adjacent to zinc finger domain, 2Ba
chr17_+_26352372 0.63 ENSDART00000155177
grid1a
glutamate receptor, ionotropic, delta 1a
chr24_+_7800486 0.62 ENSDART00000145504
ptprh
protein tyrosine phosphatase, receptor type, h
chr2_-_23172708 0.62 ENSDART00000041365
prrx1a
paired related homeobox 1a
chr25_+_31323978 0.62 ENSDART00000067030
lsp1
lymphocyte-specific protein 1
chr19_+_10979983 0.61 ENSDART00000142975
si:ch1073-70f20.1
si:ch1073-70f20.1
chr9_-_21912227 0.61 ENSDART00000145576
lmo7a
LIM domain 7a
chr16_-_36834505 0.60 ENSDART00000141275
ENSDART00000139588
ENSDART00000041993
pnp4b
purine nucleoside phosphorylase 4b
chr25_-_1235457 0.60 ENSDART00000093093
coro2bb
coronin, actin binding protein, 2Bb
chr4_+_5318901 0.59 ENSDART00000067378
si:ch211-214j24.10
si:ch211-214j24.10
chr18_+_45504362 0.57 ENSDART00000140089
cngb1a
cyclic nucleotide gated channel beta 1a
chr15_-_47956388 0.57 ENSDART00000116506
si:ch1073-111c8.3
si:ch1073-111c8.3
chr7_-_52558495 0.55 ENSDART00000138263
ENSDART00000009938
ENSDART00000174292
ENSDART00000174218
ENSDART00000174335
tcf12
transcription factor 12
chr8_-_21988833 0.55 ENSDART00000167708
nphp4
nephronophthisis 4
chr22_+_3303671 0.53 ENSDART00000075049
gipc3
GIPC PDZ domain containing family, member 3
chr23_-_36418059 0.53 ENSDART00000135232
znf740b
zinc finger protein 740b
chr22_+_567733 0.52 ENSDART00000171036
usp49
ubiquitin specific peptidase 49
chr21_-_24632778 0.51 ENSDART00000132533
ENSDART00000058370
arhgap32b
Rho GTPase activating protein 32b
chr16_-_19254323 0.50 ENSDART00000138744
dnah11
dynein, axonemal, heavy chain 11
chr5_+_32141790 0.49 ENSDART00000041504
tescb
tescalcin b
chr19_-_26863626 0.49 ENSDART00000145568
prrt1
proline-rich transmembrane protein 1
chr17_-_24439672 0.48 ENSDART00000155020
wdpcp
WD repeat containing planar cell polarity effector
chr2_+_56891858 0.47 ENSDART00000159912
zgc:85843
zgc:85843
chr23_+_30898013 0.47 ENSDART00000146859
cables2a
Cdk5 and Abl enzyme substrate 2a
chr2_+_38608290 0.45 ENSDART00000159066
cdh24b
cadherin 24, type 2b
chr4_+_20263097 0.45 ENSDART00000138820
lrtm2a
leucine-rich repeats and transmembrane domains 2a
chr16_-_49846359 0.45 ENSDART00000184246
znf385d
zinc finger protein 385D
chr8_-_1051438 0.44 ENSDART00000067093
ENSDART00000170737
smyd1b
SET and MYND domain containing 1b
chr17_-_22324727 0.44 ENSDART00000160341
CU104709.1

chr17_+_45454943 0.44 ENSDART00000074838
kcnk3b
potassium channel, subfamily K, member 3b
chr9_+_44430974 0.44 ENSDART00000056846
ppp1r1c
protein phosphatase 1, regulatory (inhibitor) subunit 1C
chr6_+_55277419 0.42 ENSDART00000083670
CABZ01041604.1

chr7_-_41693004 0.41 ENSDART00000121509
malrd1
MAM and LDL receptor class A domain containing 1
chr5_+_43870389 0.41 ENSDART00000141002
zgc:112966
zgc:112966
chr10_-_5022176 0.40 ENSDART00000148277
hnrnpdl
heterogeneous nuclear ribonucleoprotein D-like
chr24_-_23942722 0.40 ENSDART00000080810
arxa
aristaless related homeobox a
chr22_+_11775269 0.40 ENSDART00000140272
krt96
keratin 96
chr7_-_24005268 0.39 ENSDART00000173608
si:dkey-183c6.9
si:dkey-183c6.9
chr15_-_1941042 0.39 ENSDART00000112946
ENSDART00000155504
dock10
dedicator of cytokinesis 10
chr23_+_19814371 0.39 ENSDART00000182897
emd
emerin (Emery-Dreifuss muscular dystrophy)
chr7_-_56793739 0.38 ENSDART00000082842
si:ch211-146m13.3
si:ch211-146m13.3
chr8_+_48858132 0.37 ENSDART00000124737
ENSDART00000079644
tp73
tumor protein p73
chr21_-_43482426 0.37 ENSDART00000192901
ankrd46a
ankyrin repeat domain 46a
chr22_-_32360464 0.37 ENSDART00000148886
pcbp4
poly(rC) binding protein 4
chr20_-_53321499 0.36 ENSDART00000179894
ENSDART00000127427
ENSDART00000084952
wasf1
WAS protein family, member 1
chr13_-_13751017 0.36 ENSDART00000180182
ky
kyphoscoliosis peptidase
chr13_-_47800342 0.35 ENSDART00000121817
fbln7
fibulin 7
chr7_-_29223614 0.35 ENSDART00000173598
herc1
HECT and RLD domain containing E3 ubiquitin protein ligase family member 1
chr1_-_12394048 0.35 ENSDART00000146067
ENSDART00000134708
sclt1
sodium channel and clathrin linker 1
chr16_+_40563533 0.33 ENSDART00000190368
tp53inp1
tumor protein p53 inducible nuclear protein 1
chr12_-_7807298 0.32 ENSDART00000191355
ank3b
ankyrin 3b
chr11_-_3308569 0.32 ENSDART00000036581
cdk2
cyclin-dependent kinase 2
chr2_-_30987538 0.32 ENSDART00000148157
emilin2a
elastin microfibril interfacer 2a
chr6_+_58508420 0.32 ENSDART00000153740
chrna4a
cholinergic receptor, nicotinic, alpha 4a
chr20_-_2725930 0.31 ENSDART00000081643
akirin2
akirin 2
chr25_+_35212919 0.31 ENSDART00000180127
ano5a
anoctamin 5a
chr16_-_13109749 0.31 ENSDART00000142610
prkcg
protein kinase C, gamma
chr10_-_28483672 0.30 ENSDART00000139994
bbx
bobby sox homolog (Drosophila)
chr17_+_37645633 0.30 ENSDART00000085500
tmem229b
transmembrane protein 229B
chr21_+_10756154 0.29 ENSDART00000074833
rx3
retinal homeobox gene 3
chr23_-_35064785 0.29 ENSDART00000172240
BX294434.1

chr8_+_8532407 0.28 ENSDART00000169276
ENSDART00000138993
grm6a
glutamate receptor, metabotropic 6a
chr17_-_33407843 0.28 ENSDART00000129416
BX323819.1

chr17_-_21441464 0.26 ENSDART00000031490
vax1
ventral anterior homeobox 1
chr11_-_37120954 0.25 ENSDART00000172074
NINJ1
si:ch1073-278o19.1
chr17_-_15528597 0.24 ENSDART00000150232
fyna
FYN proto-oncogene, Src family tyrosine kinase a
chr15_+_31515976 0.24 ENSDART00000156471
tex26
testis expressed 26
chr19_-_35596207 0.23 ENSDART00000136811
col8a2
collagen, type VIII, alpha 2
chr8_+_24740013 0.23 ENSDART00000126897
lamtor5
late endosomal/lysosomal adaptor, MAPK and MTOR activator 5
chr13_+_31297016 0.23 ENSDART00000141786
ENSDART00000086143
antxr1d
anthrax toxin receptor 1d
chr4_+_5193198 0.22 ENSDART00000067388
fgf23
fibroblast growth factor 23
chr1_-_40994259 0.22 ENSDART00000101562
adra2c
adrenoceptor alpha 2C
chr2_+_22495274 0.20 ENSDART00000167915
lrrc8da
leucine rich repeat containing 8 VRAC subunit Da
chr12_+_31460877 0.20 ENSDART00000031154
gucy2g
guanylate cyclase 2g
chr20_+_27020201 0.20 ENSDART00000126919
ENSDART00000016014
chga
chromogranin A
chr20_-_2725594 0.20 ENSDART00000152120
akirin2
akirin 2
chr16_-_47245563 0.20 ENSDART00000190225
LO017877.2

chr1_-_191971 0.20 ENSDART00000164091
ENSDART00000159237
grtp1a
growth hormone regulated TBC protein 1a
chr9_-_7421135 0.19 ENSDART00000144600
bin1a
bridging integrator 1a
chr2_-_32457919 0.19 ENSDART00000132792
ENSDART00000041319
slc4a2a
solute carrier family 4 (anion exchanger), member 2a
chr13_-_9318891 0.19 ENSDART00000137364
si:dkey-33c12.3
si:dkey-33c12.3
chr21_-_11820379 0.18 ENSDART00000126640
RHOBTB3
si:dkey-6b12.5
chr22_+_661711 0.18 ENSDART00000113795
elf3
E74-like factor 3 (ets domain transcription factor, epithelial-specific )
chr15_+_28318005 0.17 ENSDART00000175860
myo1cb
myosin Ic, paralog b
chr21_+_26389391 0.16 ENSDART00000077197
tmsb
thymosin, beta
chr8_-_33154677 0.16 ENSDART00000133300
zbtb34
zinc finger and BTB domain containing 34
chr20_-_2619316 0.16 ENSDART00000185777
bub1
BUB1 mitotic checkpoint serine/threonine kinase
chr23_+_21459263 0.16 ENSDART00000104209
her4.3
hairy-related 4, tandem duplicate 3
chr23_-_21471022 0.16 ENSDART00000104206
her4.2
hairy-related 4, tandem duplicate 2
chr24_+_27023616 0.15 ENSDART00000089541
dip2ca
disco-interacting protein 2 homolog Ca
chr14_+_25817246 0.15 ENSDART00000136733
glra1
glycine receptor, alpha 1
chr20_-_47732703 0.15 ENSDART00000193975
tfap2d
transcription factor AP-2 delta (activating enhancer binding protein 2 delta)
chr16_-_45854882 0.15 ENSDART00000027013
ENSDART00000128068
ntrk1
neurotrophic tyrosine kinase, receptor, type 1
chr6_+_54711306 0.14 ENSDART00000074605
pkp1b
plakophilin 1b
chr15_+_1372343 0.13 ENSDART00000152285
schip1
schwannomin interacting protein 1
chr16_-_47483142 0.13 ENSDART00000147072
cthrc1b
collagen triple helix repeat containing 1b
chr21_-_14775724 0.12 ENSDART00000043239
glulc
glutamate-ammonia ligase (glutamine synthase) c
chr22_+_28446365 0.12 ENSDART00000189359
abi3bpb
ABI family, member 3 (NESH) binding protein b
chr14_-_41369629 0.12 ENSDART00000173040
cstf2
cleavage stimulation factor, 3' pre-RNA, subunit 2
chr25_+_9003230 0.11 ENSDART00000180330
ENSDART00000142917
rag1
recombination activating gene 1
chr13_-_40316367 0.11 ENSDART00000009343
pyroxd2
pyridine nucleotide-disulphide oxidoreductase domain 2
chr21_-_14773692 0.11 ENSDART00000142145
glulc
glutamate-ammonia ligase (glutamine synthase) c
chr14_+_25817628 0.11 ENSDART00000047680
glra1
glycine receptor, alpha 1
chr15_+_59417 0.10 ENSDART00000187260
AXL
AXL receptor tyrosine kinase
chr10_-_27049170 0.10 ENSDART00000143451
cnih2
cornichon family AMPA receptor auxiliary protein 2
chr11_+_3308656 0.10 ENSDART00000082458
sarnp
SAP domain containing ribonucleoprotein
chr15_-_23908779 0.09 ENSDART00000088808
usp32
ubiquitin specific peptidase 32
chr15_-_3736149 0.08 ENSDART00000182986
lpar6a
lysophosphatidic acid receptor 6a
chr2_-_10563576 0.08 ENSDART00000185818
ENSDART00000190887
ccdc18
coiled-coil domain containing 18
chr15_-_3736773 0.08 ENSDART00000090624
lpar6a
lysophosphatidic acid receptor 6a
chr13_-_4018888 0.08 ENSDART00000058238
tjap1
tight junction associated protein 1 (peripheral)
chr12_-_26406323 0.07 ENSDART00000131896
myoz1b
myozenin 1b
chr13_-_16226312 0.07 ENSDART00000163952
zgc:110045
zgc:110045
chr2_-_52020049 0.07 ENSDART00000128198
ENSDART00000135331
scn12aa
sodium channel, voltage gated, type XII, alpha a
chr12_-_46176115 0.07 ENSDART00000152848
si:ch211-226h7.8
si:ch211-226h7.8
chr5_-_5831037 0.07 ENSDART00000112856
zmp:0000000846
zmp:0000000846
chr10_+_35422802 0.07 ENSDART00000147303
hhla2a.1
HERV-H LTR-associating 2a, tandem duplicate 1
chr25_+_35706493 0.06 ENSDART00000176741
kif21a
kinesin family member 21A
chr15_+_16521785 0.06 ENSDART00000062191
galnt17
polypeptide N-acetylgalactosaminyltransferase 17
chr25_+_29688671 0.06 ENSDART00000073478
brd1b
bromodomain containing 1b
chr8_+_49096486 0.06 ENSDART00000192998
zgc:56525
zgc:56525
chr4_+_6840223 0.06 ENSDART00000161329
dock4b
dedicator of cytokinesis 4b
chr15_+_28268135 0.05 ENSDART00000152536
ENSDART00000188550
myo1cb
myosin Ic, paralog b
chr15_+_35718354 0.05 ENSDART00000110003
nyap2a
neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 2a
chr7_+_11459235 0.05 ENSDART00000159611
il16
interleukin 16
chr7_+_66822229 0.05 ENSDART00000112109
lyve1a
lymphatic vessel endothelial hyaluronic receptor 1a
chr5_-_29112956 0.04 ENSDART00000132726
whrnb
whirlin b
chr1_-_58880613 0.04 ENSDART00000188136
CABZ01084501.2

chr18_+_33340868 0.03 ENSDART00000099139
v2rh14
vomeronasal 2 receptor, h14
chr12_-_431249 0.03 ENSDART00000083827
hs3st3l
heparan sulfate (glucosamine) 3-O-sulfotransferase 3-like
chr7_-_41489997 0.03 ENSDART00000174300
smarcd3b
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3b
chr17_+_24222190 0.03 ENSDART00000181698
ENSDART00000189411
ehbp1
EH domain binding protein 1
chr12_+_45677293 0.03 ENSDART00000152850
ENSDART00000153047
si:ch73-111m19.2
si:ch73-111m19.2
chr7_-_52334840 0.03 ENSDART00000174173
CR938716.1

chr15_-_34214440 0.03 ENSDART00000167052
etv1
ets variant 1
chr2_-_37896646 0.03 ENSDART00000075931
hbl1
hexose-binding lectin 1
chr8_+_25342896 0.02 ENSDART00000129032
CR847543.1

chr18_+_34225520 0.02 ENSDART00000126115
v2rl1
vomeronasal 2 receptor, l1
chr13_-_49819027 0.02 ENSDART00000067824
b3galnt2
beta-1,3-N-acetylgalactosaminyltransferase 2
chr25_-_31739309 0.02 ENSDART00000098896
acot19
acyl-CoA thioesterase 19
chr4_+_4272622 0.01 ENSDART00000164810
ano2
anoctamin 2
chr9_+_41612642 0.01 ENSDART00000138473
spegb
SPEG complex locus b
chr23_-_1144425 0.01 ENSDART00000098271
psmb11b
proteasome subunit beta11b
chr10_-_7636340 0.00 ENSDART00000166234
ubxn8
UBX domain protein 8

Network of associatons between targets according to the STRING database.

First level regulatory network of ebf3a-1+si:ch211-51e8.2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.2 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.3 1.4 GO:0031446 regulation of twitch skeletal muscle contraction(GO:0014724) regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448) negative regulation of striated muscle contraction(GO:0045988) relaxation of skeletal muscle(GO:0090076)
0.2 0.9 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.2 0.9 GO:0060300 regulation of cytokine activity(GO:0060300) regulation of receptor binding(GO:1900120) regulation of chemokine activity(GO:1900136)
0.2 0.7 GO:0010898 regulation of triglyceride catabolic process(GO:0010896) positive regulation of triglyceride catabolic process(GO:0010898)
0.2 0.7 GO:0015677 copper ion import(GO:0015677)
0.2 0.9 GO:0071691 cardiac muscle thin filament assembly(GO:0071691)
0.1 1.2 GO:1904071 presynaptic active zone assembly(GO:1904071)
0.1 0.2 GO:0072502 cellular anion homeostasis(GO:0030002) cellular monovalent inorganic anion homeostasis(GO:0030320) cellular phosphate ion homeostasis(GO:0030643) cellular divalent inorganic anion homeostasis(GO:0072501) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.1 0.5 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.1 1.3 GO:0030431 sleep(GO:0030431)
0.1 0.4 GO:0003322 pancreatic A cell development(GO:0003322)
0.1 0.3 GO:0060898 eye field cell fate commitment involved in camera-type eye formation(GO:0060898)
0.1 0.3 GO:0071361 cellular response to ethanol(GO:0071361)
0.1 1.1 GO:0016199 axon midline choice point recognition(GO:0016199)
0.1 0.3 GO:0060074 synapse maturation(GO:0060074)
0.1 1.1 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.1 0.4 GO:0033119 negative regulation of RNA splicing(GO:0033119) negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.1 0.6 GO:0086002 cardiac muscle cell action potential involved in contraction(GO:0086002)
0.1 0.2 GO:0090278 negative regulation of peptide secretion(GO:0002792) negative regulation of peptide hormone secretion(GO:0090278)
0.1 0.7 GO:0033198 response to ATP(GO:0033198)
0.1 1.3 GO:0021884 forebrain neuron development(GO:0021884)
0.0 17.7 GO:0046777 protein autophosphorylation(GO:0046777)
0.0 1.1 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.0 0.2 GO:0071881 adenylate cyclase-inhibiting adrenergic receptor signaling pathway(GO:0071881)
0.0 0.2 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.0 0.9 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 0.2 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.0 1.0 GO:0035329 hippo signaling(GO:0035329)
0.0 0.3 GO:0090259 regulation of retinal ganglion cell axon guidance(GO:0090259)
0.0 0.3 GO:0035094 response to nicotine(GO:0035094)
0.0 1.8 GO:0060395 SMAD protein signal transduction(GO:0060395)
0.0 0.2 GO:1901998 toxin transport(GO:1901998)
0.0 0.3 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.4 GO:2000601 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.2 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.0 0.2 GO:0002446 neutrophil mediated immunity(GO:0002446)
0.0 0.1 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.0 0.7 GO:0048010 vascular endothelial growth factor receptor signaling pathway(GO:0048010)
0.0 0.2 GO:1904263 positive regulation of TORC1 signaling(GO:1904263)
0.0 0.4 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.6 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 0.8 GO:0000281 mitotic cytokinesis(GO:0000281)
0.0 0.5 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.3 GO:0048936 peripheral nervous system neuron axonogenesis(GO:0048936)
0.0 0.1 GO:0098789 mRNA cleavage involved in mRNA processing(GO:0098787) pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.0 0.7 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 1.7 GO:0051259 protein oligomerization(GO:0051259)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.4 GO:0031673 H zone(GO:0031673)
0.2 0.5 GO:0097541 axonemal basal plate(GO:0097541)
0.1 2.2 GO:0005903 brush border(GO:0005903)
0.1 1.2 GO:0098982 GABA-ergic synapse(GO:0098982)
0.1 1.7 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.1 0.5 GO:0001650 fibrillar center(GO:0001650)
0.1 0.6 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.9 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.7 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.0 0.2 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.7 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.7 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0 0.5 GO:0097546 ciliary base(GO:0097546)
0.0 0.5 GO:0031430 M band(GO:0031430)
0.0 0.4 GO:0031209 SCAR complex(GO:0031209)
0.0 0.2 GO:0042583 chromaffin granule(GO:0042583)
0.0 0.1 GO:0097519 DNA recombinase complex(GO:0097519)
0.0 0.4 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 1.4 GO:0005882 intermediate filament(GO:0005882)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.5 GO:0004385 guanylate kinase activity(GO:0004385)
0.4 2.2 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.3 0.9 GO:0031701 angiotensin receptor binding(GO:0031701)
0.2 3.1 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.2 1.1 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.2 0.9 GO:0001223 transcription coactivator binding(GO:0001223)
0.2 0.7 GO:0052851 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.1 0.4 GO:0005252 open rectifier potassium channel activity(GO:0005252)
0.1 0.9 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.1 0.4 GO:0034046 poly(G) binding(GO:0034046)
0.1 0.6 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.1 1.2 GO:0098882 structural constituent of presynaptic active zone(GO:0098882)
0.1 0.7 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.1 0.9 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.9 GO:0070411 I-SMAD binding(GO:0070411)
0.0 1.9 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.6 GO:0043855 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) intracellular cAMP activated cation channel activity(GO:0005222) intracellular cGMP activated cation channel activity(GO:0005223) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0 0.3 GO:0001642 group III metabotropic glutamate receptor activity(GO:0001642)
0.0 0.4 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.2 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
0.0 0.7 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 1.1 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.0 0.2 GO:0016211 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.0 0.3 GO:0030332 cyclin binding(GO:0030332)
0.0 0.2 GO:0048156 tau protein binding(GO:0048156)
0.0 0.3 GO:0016934 excitatory extracellular ligand-gated ion channel activity(GO:0005231) extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 0.7 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.4 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.2 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0 1.3 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.2 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.0 0.6 GO:0030371 translation repressor activity(GO:0030371)
0.0 1.9 GO:0008080 N-acetyltransferase activity(GO:0008080)
0.0 0.4 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.6 GO:1904315 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0 0.1 GO:1990238 double-stranded DNA endodeoxyribonuclease activity(GO:1990238)
0.0 17.8 GO:0004674 protein serine/threonine kinase activity(GO:0004674)
0.0 0.5 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.0 0.3 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.0 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 0.2 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.1 0.9 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.7 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.5 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 1.2 SIG CHEMOTAXIS Genes related to chemotaxis
0.0 0.3 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.3 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.2 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.1 0.9 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.1 1.4 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.7 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 0.8 REACTOME KINESINS Genes involved in Kinesins
0.0 0.2 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.0 0.9 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.5 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 1.1 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.3 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 0.6 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.3 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.3 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport