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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for egr1

Z-value: 0.48

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Transcription factors associated with egr1

Gene Symbol Gene ID Gene Info
ENSDARG00000037421 early growth response 1
ENSDARG00000115563 early growth response 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
egr1dr11_v1_chr14_-_21336385_213363850.456.3e-02Click!

Activity profile of egr1 motif

Sorted Z-values of egr1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr20_+_54356272 0.98 ENSDART00000145735
zinc finger protein 410
chr23_+_39606108 0.89 ENSDART00000109464
G0/G1 switch 2
chr16_-_54405976 0.86 ENSDART00000055395
odd-skipped related transciption factor 2
chr2_-_22535 0.72 ENSDART00000157877

chr14_+_48960078 0.70 ENSDART00000165514
macrophage migration inhibitory factor
chr20_-_51697437 0.68 ENSDART00000145391
si:ch211-14a11.2
chr20_-_52631998 0.66 ENSDART00000145283
ENSDART00000139072
si:ch211-221n20.1
chr3_-_32180796 0.63 ENSDART00000133191
ENSDART00000055308
PIH1 domain containing 1
chr19_-_25427255 0.63 ENSDART00000036854
glucocorticoid induced 1a
chr16_-_12512568 0.61 ENSDART00000055161
ENSDART00000160906
cytochrome c oxidase subunit VIb polypeptide 2
chr1_-_8653385 0.61 ENSDART00000193041
actin, beta 1
chr14_+_2243 0.61 ENSDART00000191193
cytokine like 1
chr12_-_990149 0.60 ENSDART00000054367
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2b
chr20_-_22778394 0.57 ENSDART00000152645
FIP1 like 1a (S. cerevisiae)
chr24_+_24923166 0.57 ENSDART00000065288
phosphate cytidylyltransferase 1, choline, beta a
chr2_+_16710889 0.56 ENSDART00000017852
UBX domain protein 7
chr7_-_10560964 0.55 ENSDART00000172761
ENSDART00000170476
5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase)
chr18_+_5490668 0.54 ENSDART00000167035
muscle-specific beta 1 integrin binding protein 2
chr19_+_7154500 0.54 ENSDART00000035967
ENSDART00000160894
bromodomain containing 2a
chr5_+_337215 0.53 ENSDART00000167982
ring finger protein 170
chr17_+_24821627 0.53 ENSDART00000112389
WD repeat domain 43
chr17_+_53311618 0.53 ENSDART00000166517
ankyrin repeat and SOCS box containing 2b
chr21_-_308852 0.52 ENSDART00000151613
LHFPL tetraspan subfamily member 2a
chr22_-_80533 0.52 ENSDART00000183124

chr1_-_49434798 0.51 ENSDART00000150842
ENSDART00000150789
si:dkeyp-80c12.10
chr20_+_13894123 0.49 ENSDART00000007744
solute carrier family 30 (zinc transporter), member 1a
chr24_+_3328354 0.49 ENSDART00000147468
3-hydroxybutyrate dehydrogenase, type 1
chr16_-_13595027 0.49 ENSDART00000060004
ntl-dependent gene 5
chr15_-_20939579 0.49 ENSDART00000152371
ubiquitin specific peptidase 2a
chr16_+_23978978 0.47 ENSDART00000058964
ENSDART00000135084
apolipoprotein A-II
chr19_+_48102560 0.45 ENSDART00000164464
UTP18 small subunit (SSU) processome component
chr17_-_2584423 0.45 ENSDART00000013506
zona pellucida glycoprotein 3, tandem duplicate 2
chr14_+_17397534 0.44 ENSDART00000180162
ENSDART00000129838
ring finger protein 212
chr9_-_52386733 0.43 ENSDART00000171721
death associated protein 1b
chr7_+_20563305 0.42 ENSDART00000169661
si:dkey-19b23.10
chr2_-_48753873 0.41 ENSDART00000189556

chr18_-_50956280 0.41 ENSDART00000058457
suppression of tumorigenicity 7
chr18_+_36601556 0.41 ENSDART00000127825
CLK4-associating serine/arginine rich protein
chr24_+_37406535 0.40 ENSDART00000138264
si:ch211-183d21.1
chr25_-_16146851 0.40 ENSDART00000104043
dickkopf WNT signaling pathway inhibitor 3b
chr19_+_636886 0.38 ENSDART00000149192
telomerase reverse transcriptase
chr5_+_72377851 0.38 ENSDART00000160479
lectin, mannose-binding 2-like a
chr18_+_36601403 0.38 ENSDART00000192905
CLK4-associating serine/arginine rich protein
chr2_+_105748 0.38 ENSDART00000169601

chr24_+_42127983 0.36 ENSDART00000190157
ENSDART00000176032
ENSDART00000175790
WW domain containing E3 ubiquitin protein ligase 1
chr12_+_48851381 0.35 ENSDART00000187241
ENSDART00000187796
discs, large homolog 5b (Drosophila), tandem duplicate 1
chr24_-_37688398 0.34 ENSDART00000141414
zgc:112185
chr6_-_35446110 0.33 ENSDART00000058773
regulator of G protein signaling 16
chr21_-_280769 0.33 ENSDART00000157753
plasminogen receptor, C-terminal lysine transmembrane protein
chr6_+_2093367 0.32 ENSDART00000148396
transglutaminase 2b
chr7_+_41340520 0.31 ENSDART00000005127
GRB2 associated, regulator of MAPK1
chr12_-_49168398 0.31 ENSDART00000186608

chr2_-_54639964 0.31 ENSDART00000100103
acyl-CoA synthetase short chain family member 2 like
chr16_+_10918252 0.30 ENSDART00000172949
POU class 2 homeobox 2a
chr10_-_35030673 0.30 ENSDART00000135338
SPT20 homolog, SAGA complex component
chr15_+_3284684 0.29 ENSDART00000179778
forkhead box O1 a
chr16_+_4658250 0.29 ENSDART00000006212
si:ch1073-284b18.2
chr7_-_46019756 0.28 ENSDART00000162583
zgc:162297
chr5_+_36513605 0.27 ENSDART00000013590
wingless-type MMTV integration site family, member 11
chr9_-_24413008 0.27 ENSDART00000135897
transmembrane protein with EGF-like and two follistatin-like domains 2a
chr3_-_22829710 0.26 ENSDART00000055659
cytochrome b561
chr20_-_45661049 0.26 ENSDART00000124582
ENSDART00000131251
N-ethylmaleimide-sensitive factor attachment protein, beta b
chr18_+_402048 0.26 ENSDART00000166345
glucose-6-phosphate isomerase b
chr5_-_2689753 0.25 ENSDART00000172699
guanine nucleotide binding protein (G protein), gamma 10
chr15_-_47848544 0.24 ENSDART00000098711
eukaryotic translation initiation factor 3, subunit K
chr8_-_52859301 0.24 ENSDART00000162004
nuclear receptor subfamily 5, group A, member 1a
chr19_-_11237125 0.24 ENSDART00000163921
signal sequence receptor, beta
chr23_+_44374041 0.23 ENSDART00000136056
eph receptor B4b
chr14_-_15699528 0.23 ENSDART00000161123
neuralized E3 ubiquitin protein ligase 1B
chr16_-_13965518 0.23 ENSDART00000138304
si:dkey-85k15.4
chr21_+_103194 0.23 ENSDART00000162755
zyg-11 related, cell cycle regulator
chr18_-_50845804 0.22 ENSDART00000158517
si:cabz01113374.3
chr25_-_37501371 0.22 ENSDART00000160498

chr2_-_17827983 0.22 ENSDART00000166518
protein tyrosine phosphatase, receptor type, f, b
chr6_+_21740672 0.21 ENSDART00000193734
lipoma HMGIC fusion partner-like 4a
chr15_+_3284416 0.21 ENSDART00000187665
ENSDART00000171723
forkhead box O1 a
chr11_+_45436703 0.21 ENSDART00000168295
ENSDART00000173293
son of sevenless homolog 1 (Drosophila)
chr11_+_45461419 0.20 ENSDART00000173424
son of sevenless homolog 1 (Drosophila)
chr13_+_12739283 0.20 ENSDART00000102279
leucine rich repeat and Ig domain containing 2b
chr17_+_53311243 0.20 ENSDART00000160241
ENSDART00000160009
ENSDART00000162239
ankyrin repeat and SOCS box containing 2b
chr7_-_22981796 0.20 ENSDART00000167565
si:dkey-171c9.3
chr1_-_8917902 0.19 ENSDART00000137900
glutamate receptor, ionotropic, N-methyl D-aspartate 2A, b
chr3_+_40809011 0.19 ENSDART00000033713
actin related protein 2/3 complex, subunit 1B
chr18_-_5103931 0.19 ENSDART00000188091
programmed cell death 10a
chr6_-_15604157 0.19 ENSDART00000141597
leucine rich repeat (in FLII) interacting protein 1b
chr3_+_32492467 0.18 ENSDART00000151329
transient receptor potential cation channel, subfamily M, member 4a
chr2_-_17828279 0.18 ENSDART00000083314
protein tyrosine phosphatase, receptor type, f, b
chr3_+_45687266 0.18 ENSDART00000131652
G protein-coupled receptor 146
chr21_-_22325124 0.18 ENSDART00000142100
glycerophosphodiester phosphodiesterase domain containing 4b
chr8_-_34762163 0.18 ENSDART00000114080
SET domain containing 1B, b
chr3_-_61185746 0.18 ENSDART00000028219
parvalbumin 4
chr10_+_252425 0.18 ENSDART00000059478
leucine rich repeat containing 32
chr21_+_11415224 0.18 ENSDART00000049036
zgc:92275
chr14_-_21218891 0.17 ENSDART00000158294
protein phosphatase 2, regulatory subunit B, gamma b
chr15_+_43906043 0.17 ENSDART00000010881
N-acetylated alpha-linked acidic dipeptidase 2
chr1_-_411331 0.16 ENSDART00000092524
RAS p21 protein activator 3
chr15_-_17099560 0.16 ENSDART00000101724
v-mos Moloney murine sarcoma viral oncogene homolog
chr6_-_15604417 0.16 ENSDART00000157817
leucine rich repeat (in FLII) interacting protein 1b
chr22_+_38192568 0.16 ENSDART00000126323
ceruloplasmin
chr14_-_14566417 0.15 ENSDART00000159056
si:dkey-27i16.2
chr12_+_41510492 0.15 ENSDART00000170976
ENSDART00000176164
kinesin family member 5B, b
chr20_-_26383368 0.15 ENSDART00000024518
ENSDART00000087844
estrogen receptor 1
chr2_+_38924975 0.15 ENSDART00000109219
RAS (RAD and GEM)-like GTP binding 2
chr7_+_22981909 0.15 ENSDART00000122449
cyclin B3
chr17_-_25831569 0.15 ENSDART00000148743
hedgehog acyltransferase
chr4_+_70556298 0.15 ENSDART00000170985
si:dkey-11d20.1
chr8_-_53490376 0.15 ENSDART00000158789
choline dehydrogenase
chr9_-_105135 0.15 ENSDART00000180126

chr6_+_59808677 0.14 ENSDART00000164469
calcium/calmodulin-dependent serine protein kinase b
chr12_-_15620090 0.14 ENSDART00000038032
acyl-CoA binding domain containing 4
chr21_+_3941758 0.14 ENSDART00000181345
senataxin
chr3_-_40965596 0.14 ENSDART00000137188
cytochrome P450, family 3, subfamily c, polypeptide 2
chr12_-_20303438 0.14 ENSDART00000153057
rhomboid 5 homolog 1b (Drosophila)
chr19_+_935565 0.14 ENSDART00000113368
ring finger protein 5
chr1_-_59571758 0.14 ENSDART00000193546
ENSDART00000167087
WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1
chr3_-_15444396 0.14 ENSDART00000104361
si:dkey-56d12.4
chr5_+_43870389 0.13 ENSDART00000141002
zgc:112966
chr2_-_48966431 0.13 ENSDART00000147948
potassium inwardly-rectifying channel, subfamily J, member 9
chr18_+_16246806 0.13 ENSDART00000142584
ALX homeobox 1
chr23_-_29556844 0.13 ENSDART00000138021
retinol binding protein 7a, cellular
chr14_+_36220479 0.13 ENSDART00000148319
paired-like homeodomain 2
chr25_-_32888115 0.13 ENSDART00000087586
C2 calcium dependent domain containing 4A
chr25_+_37348730 0.13 ENSDART00000156639
peptidase domain containing associated with muscle regeneration 1
chr1_+_54673846 0.12 ENSDART00000145018
G protein-coupled receptor, class C, group 5, member Bb
chr23_+_20422661 0.12 ENSDART00000144047
ENSDART00000104336
troponin C type 2 (fast)
chr19_-_48039400 0.12 ENSDART00000166748
ENSDART00000165921
colony stimulating factor 3 (granulocyte) b
chr20_-_54381034 0.12 ENSDART00000136779
ectonucleoside triphosphate diphosphohydrolase 5b
chr21_-_33126697 0.12 ENSDART00000189293
ENSDART00000084559

chr2_+_20793982 0.12 ENSDART00000014785
proteoglycan 4a
chr19_+_58954 0.12 ENSDART00000162379
collagen, type XIV, alpha 1b
chr9_+_51784922 0.12 ENSDART00000125850
CD302 molecule
chr21_+_7900107 0.11 ENSDART00000056560
cholesterol 25-hydroxylase like 2
chr25_+_1304173 0.11 ENSDART00000155229
relaxin/insulin-like family peptide receptor 3.3b
chr11_+_1565806 0.11 ENSDART00000137479
v-myb avian myeloblastosis viral oncogene homolog-like 2b
chr16_-_6821927 0.11 ENSDART00000149070
ENSDART00000149570
myelin basic protein b
chr15_-_19250543 0.11 ENSDART00000092705
ENSDART00000138895
immunoglobulin superfamily, member 9Ba
chr6_-_13206255 0.11 ENSDART00000065373
eukaryotic translation elongation factor 1 beta 2
chr1_-_59422880 0.11 ENSDART00000167244
si:ch211-188p14.2
chr22_+_1751640 0.11 ENSDART00000162093
zinc finger protein 1169
chr14_+_7939398 0.11 ENSDART00000189773
CXXC finger protein 5b
chr25_+_36315127 0.10 ENSDART00000191984
zgc:165555
chr15_-_47822597 0.10 ENSDART00000193236
ENSDART00000161391

chr11_-_42418374 0.10 ENSDART00000160704
sarcolemma associated protein a
chr18_-_49078428 0.10 ENSDART00000160702
ENSDART00000174103

chr4_-_23839789 0.10 ENSDART00000143571
USP6 N-terminal like
chr10_+_2742499 0.10 ENSDART00000122847
G protein-coupled receptor kinase 5
chr5_+_15667874 0.10 ENSDART00000127015
serine/arginine repetitive matrix 4
chr10_-_15919839 0.10 ENSDART00000065032
phosphatidylinositol-4-phosphate 5-kinase, type I, beta a
chr4_-_64709908 0.09 ENSDART00000161032
si:dkey-9i5.2
chr21_+_19517492 0.08 ENSDART00000123168
ENSDART00000187993
granzyme K
chr6_+_14301214 0.08 ENSDART00000129491
transmembrane protein 182b
chr1_-_53259746 0.08 ENSDART00000134222
interleukin 15
chr4_+_39742119 0.08 ENSDART00000176004

chr11_+_37251825 0.08 ENSDART00000169804
interleukin 17 receptor C
chr14_+_32964 0.08 ENSDART00000166173
Ly1 antibody reactive homolog (mouse)
chr8_-_15292197 0.08 ENSDART00000140867
spermatogenesis associated 6
chr25_-_36370292 0.08 ENSDART00000152766
Histone H2B 1/2
chr23_+_41800052 0.08 ENSDART00000141484
prodynorphin
chr20_-_54377933 0.08 ENSDART00000182664
ectonucleoside triphosphate diphosphohydrolase 5b
chr1_-_20271138 0.08 ENSDART00000185931
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3
chr11_-_2594045 0.07 ENSDART00000114079
NGFI-A binding protein 2 (EGR1 binding protein 2)
chr25_-_36310561 0.07 ENSDART00000181152
zgc:165555
chr7_-_12596727 0.07 ENSDART00000186413
ADAMTS-like 3
chr15_-_14486534 0.07 ENSDART00000179368
numb homolog (Drosophila)-like
chr3_+_23737795 0.07 ENSDART00000182247
homeobox B3a
chr4_-_9586713 0.07 ENSDART00000145613
SH3 and multiple ankyrin repeat domains 3b
chr17_+_20639180 0.07 ENSDART00000063624
neuropeptide Y receptor Y4
chr2_+_26288301 0.07 ENSDART00000017668
polypyrimidine tract binding protein 1a
chr19_+_43504480 0.07 ENSDART00000159421

chr7_+_20017211 0.07 ENSDART00000100808
B-cell CLL/lymphoma 6, member B
chr19_-_7225060 0.07 ENSDART00000133179
ENSDART00000151138
ENSDART00000104799
ENSDART00000128331
collagen, type XI, alpha 2
chr12_+_34273240 0.07 ENSDART00000037904
suppressor of cytokine signaling 3b
chr1_-_44940830 0.07 ENSDART00000097500
ENSDART00000134464
ENSDART00000137216
transmembrane protein 176
chr11_+_45461853 0.06 ENSDART00000173409
son of sevenless homolog 1 (Drosophila)
chr1_+_11659861 0.06 ENSDART00000054787

chr17_+_8323348 0.06 ENSDART00000169900
CDC42 binding protein kinase alpha (DMPK-like) a
chr23_-_22072460 0.06 ENSDART00000132343
polyhomeotic homolog 2a (Drosophila)
chr11_-_44347587 0.06 ENSDART00000172919
si:cabz01100188.1
chr25_+_35706493 0.06 ENSDART00000176741
kinesin family member 21A
chr5_-_12093618 0.06 ENSDART00000161542
leucine rich repeat containing 74B
chr4_+_30775376 0.06 ENSDART00000158528
si:dkey-11d20.1
chr9_-_30363770 0.06 ENSDART00000147030
synaptotagmin-like 5
chr8_+_23436411 0.06 ENSDART00000140044
forkhead box P3b
chr22_-_6499055 0.06 ENSDART00000142235
ENSDART00000183588
si:dkey-19a16.7
chr12_-_44016898 0.06 ENSDART00000175304
si:dkey-201i2.4
chr1_+_56972616 0.06 ENSDART00000152812
si:ch211-1f22.11
chr23_-_27547931 0.06 ENSDART00000144419
La ribonucleoprotein domain family, member 4Aa
chr25_+_34889061 0.06 ENSDART00000136226
spire-type actin nucleation factor 2
chr13_+_25486608 0.05 ENSDART00000057689
BCL2 associated athanogene 3
chr16_+_19029297 0.05 ENSDART00000115263
ENSDART00000114954
Rap guanine nucleotide exchange factor (GEF) 5b
chr10_+_23553533 0.05 ENSDART00000159654

chr1_+_1599979 0.05 ENSDART00000097626
urotensin II-related peptide
chr1_+_54773877 0.05 ENSDART00000129831
NLR family CARD domain containing 6
chr15_-_12319065 0.05 ENSDART00000162973
ENSDART00000170543
FXYD domain containing ion transport regulator 6
chr22_+_24770744 0.05 ENSDART00000142882
si:rp71-23d18.4
chr12_+_19030391 0.05 ENSDART00000153927
si:ch73-139e5.2
chr1_+_32528097 0.05 ENSDART00000128317
neuroligin 4a
chr1_+_49435017 0.05 ENSDART00000124833
programmed cell death 11
chr12_+_499881 0.05 ENSDART00000167527
myosin phosphatase Rho interacting protein
chr1_-_56363108 0.05 ENSDART00000021878
glucagon receptor b

Network of associatons between targets according to the STRING database.

First level regulatory network of egr1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0010312 detoxification of zinc ion(GO:0010312) stress response to zinc ion(GO:1990359)
0.1 0.4 GO:0007571 age-dependent general metabolic decline(GO:0007571)
0.1 0.6 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.1 0.6 GO:0006621 protein retention in ER lumen(GO:0006621)
0.1 0.3 GO:0010755 regulation of plasminogen activation(GO:0010755)
0.1 0.5 GO:0009396 folic acid-containing compound biosynthetic process(GO:0009396)
0.1 0.5 GO:0048745 smooth muscle tissue development(GO:0048745)
0.1 0.3 GO:0010807 regulation of synaptic vesicle priming(GO:0010807)
0.1 0.2 GO:1903358 regulation of Golgi organization(GO:1903358)
0.1 0.6 GO:0098789 mRNA cleavage involved in mRNA processing(GO:0098787) pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.1 0.2 GO:0002369 T cell cytokine production(GO:0002369)
0.1 0.5 GO:0046546 development of primary male sexual characteristics(GO:0046546)
0.1 0.2 GO:0044785 meiotic cell cycle phase transition(GO:0044771) metaphase/anaphase transition of meiotic cell cycle(GO:0044785) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994) regulation of metaphase/anaphase transition of meiotic cell cycle(GO:1902102) negative regulation of metaphase/anaphase transition of meiotic cell cycle(GO:1902103) regulation of meiotic chromosome separation(GO:1905132) negative regulation of meiotic chromosome separation(GO:1905133)
0.1 0.2 GO:0097112 gamma-aminobutyric acid receptor clustering(GO:0097112)
0.1 0.3 GO:0019427 acetate metabolic process(GO:0006083) acetyl-CoA biosynthetic process from acetate(GO:0019427)
0.0 0.1 GO:0019695 choline metabolic process(GO:0019695)
0.0 0.2 GO:0070086 ubiquitin-dependent endocytosis(GO:0070086)
0.0 0.4 GO:0097374 sensory neuron axon guidance(GO:0097374)
0.0 0.9 GO:0002574 thrombocyte differentiation(GO:0002574)
0.0 0.8 GO:0070831 basement membrane assembly(GO:0070831)
0.0 0.4 GO:0060046 binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.0 0.1 GO:0010718 positive regulation of epithelial to mesenchymal transition(GO:0010718)
0.0 0.1 GO:0061072 iris morphogenesis(GO:0061072)
0.0 0.7 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.0 0.1 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.0 0.7 GO:0060117 auditory receptor cell development(GO:0060117)
0.0 0.1 GO:0060468 negative regulation of fertilization(GO:0060467) prevention of polyspermy(GO:0060468) cortical granule exocytosis(GO:0060471)
0.0 0.2 GO:0030325 adrenal gland development(GO:0030325)
0.0 0.2 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.0 0.4 GO:0010507 negative regulation of autophagy(GO:0010507)
0.0 0.4 GO:0016925 protein sumoylation(GO:0016925)
0.0 0.3 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.3 GO:0051156 glucose 6-phosphate metabolic process(GO:0051156)
0.0 0.2 GO:0009134 nucleoside diphosphate catabolic process(GO:0009134)
0.0 0.2 GO:0060079 excitatory postsynaptic potential(GO:0060079)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0097255 R2TP complex(GO:0097255)
0.1 0.4 GO:0000333 telomerase catalytic core complex(GO:0000333)
0.1 0.6 GO:0097433 dense body(GO:0097433)
0.1 0.2 GO:0060077 inhibitory synapse(GO:0060077)
0.1 0.3 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.1 0.5 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.1 0.2 GO:0090443 FAR/SIN/STRIPAK complex(GO:0090443)
0.0 0.6 GO:0030663 COPI-coated vesicle membrane(GO:0030663)
0.0 0.6 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.1 GO:0070062 extracellular exosome(GO:0070062)
0.0 0.3 GO:0000124 SAGA complex(GO:0000124)
0.0 0.4 GO:0000795 synaptonemal complex(GO:0000795)
0.0 0.1 GO:0097224 sperm connecting piece(GO:0097224)
0.0 0.1 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.2 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0 0.3 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.0 0.2 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.3 GO:0043256 basal lamina(GO:0005605) laminin complex(GO:0043256)
0.0 0.2 GO:0016282 eukaryotic 43S preinitiation complex(GO:0016282)
0.0 0.2 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.2 GO:0048188 Set1C/COMPASS complex(GO:0048188)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0046923 ER retention sequence binding(GO:0046923)
0.1 0.4 GO:0003721 telomerase RNA reverse transcriptase activity(GO:0003721)
0.1 0.6 GO:0098973 structural constituent of postsynaptic actin cytoskeleton(GO:0098973)
0.1 0.6 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.1 0.4 GO:0070513 death domain binding(GO:0070513)
0.1 0.3 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.1 0.4 GO:0039706 co-receptor binding(GO:0039706)
0.1 0.5 GO:0050262 ribosylnicotinamide kinase activity(GO:0050262)
0.1 0.3 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.0 0.1 GO:0001160 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160)
0.0 0.3 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.0 0.4 GO:0035804 structural constituent of egg coat(GO:0035804)
0.0 0.4 GO:0005537 mannose binding(GO:0005537)
0.0 0.1 GO:0032027 myosin light chain binding(GO:0032027)
0.0 0.2 GO:1903924 estradiol binding(GO:1903924)
0.0 0.6 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.4 GO:0019789 SUMO transferase activity(GO:0019789)
0.0 0.3 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0 0.1 GO:0000254 C-4 methylsterol oxidase activity(GO:0000254)
0.0 0.3 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.1 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.3 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.2 GO:0045134 guanosine-diphosphatase activity(GO:0004382) uridine-diphosphatase activity(GO:0045134)
0.0 0.0 GO:0004377 GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity(GO:0004377)
0.0 0.2 GO:0005003 ephrin receptor activity(GO:0005003)
0.0 0.1 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.2 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.2 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 0.4 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 0.3 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 0.5 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.5 REACTOME SOS MEDIATED SIGNALLING Genes involved in SOS-mediated signalling
0.0 0.4 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.2 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.0 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 0.1 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation