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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for egr2a+egr2b

Z-value: 0.99

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Transcription factors associated with egr2a+egr2b

Gene Symbol Gene ID Gene Info
egr2b
ENSDARG00000042826 early growth response 2b
egr2a
ENSDARG00000044098 early growth response 2a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
egr2adr11_v1_chr17_-_43666166_436661660.971.8e-11Click!
egr2bdr11_v1_chr12_-_8486330_84863300.456.1e-02Click!

Activity profile of egr2a+egr2b motif

Sorted Z-values of egr2a+egr2b motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr7_-_10560964 4.58 ENSDART00000172761
ENSDART00000170476
mthfs
5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase)
chr16_+_10963602 3.40 ENSDART00000141032
pou2f2a
POU class 2 homeobox 2a
chr16_-_54405976 3.20 ENSDART00000055395
osr2
odd-skipped related transciption factor 2
chr16_+_23978978 2.99 ENSDART00000058964
ENSDART00000135084
apoa2
apolipoprotein A-II
chr15_-_20939579 2.98 ENSDART00000152371
usp2a
ubiquitin specific peptidase 2a
chr23_+_39606108 2.82 ENSDART00000109464
g0s2
G0/G1 switch 2
chr14_+_80685 2.68 ENSDART00000188443
stag3
stromal antigen 3
chr20_-_22778394 2.61 ENSDART00000152645
fip1l1a
FIP1 like 1a (S. cerevisiae)
chr3_+_60007703 2.61 ENSDART00000157351
ENSDART00000153928
ENSDART00000155876
si:ch211-110e21.3
si:ch211-110e21.3
chr15_+_31526225 2.31 ENSDART00000154456
wdr95
WD40 repeat domain 95
chr18_+_402048 2.30 ENSDART00000166345
gpib
glucose-6-phosphate isomerase b
chr15_-_20916251 2.26 ENSDART00000134053
usp2a
ubiquitin specific peptidase 2a
chr12_+_49125510 2.18 ENSDART00000185804
FO704607.1

chr25_+_24250247 2.10 ENSDART00000064646
tmem86a
transmembrane protein 86A
chr16_+_10918252 2.08 ENSDART00000172949
pou2f2a
POU class 2 homeobox 2a
chr5_-_26093945 2.06 ENSDART00000010199
ENSDART00000145096
fam219ab
family with sequence similarity 219, member Ab
chr21_-_308852 1.91 ENSDART00000151613
lhfpl2a
LHFPL tetraspan subfamily member 2a
chr5_-_72136548 1.89 ENSDART00000007827
spra
sepiapterin reductase a
chr3_-_10779777 1.87 ENSDART00000153911
znf1004
zinc finger protein 1004
chr20_+_27242595 1.85 ENSDART00000149300
si:dkey-85n7.6
si:dkey-85n7.6
chr14_-_2933185 1.82 ENSDART00000161677
ENSDART00000162446
ENSDART00000109378
si:dkey-201i24.6
si:dkey-201i24.6
chr17_-_52643970 1.77 ENSDART00000190594
spred1
sprouty-related, EVH1 domain containing 1
chr23_+_20422661 1.77 ENSDART00000144047
ENSDART00000104336
tnnc2
troponin C type 2 (fast)
chr9_+_17348745 1.76 ENSDART00000147488
slain1a
SLAIN motif family, member 1a
chr7_-_22981796 1.73 ENSDART00000167565
si:dkey-171c9.3
si:dkey-171c9.3
chr6_+_26314464 1.70 ENSDART00000115392
dzip1l
DAZ interacting zinc finger protein 1-like
chr3_+_32492467 1.67 ENSDART00000151329
trpm4a
transient receptor potential cation channel, subfamily M, member 4a
chr24_+_3963684 1.66 ENSDART00000182959
ENSDART00000185926
ENSDART00000167043
ENSDART00000033394
pfkpa
phosphofructokinase, platelet a
chr10_-_36726188 1.66 ENSDART00000157262
pimr137
Pim proto-oncogene, serine/threonine kinase, related 137
chr6_-_35446110 1.59 ENSDART00000058773
rgs16
regulator of G protein signaling 16
chr7_-_33023404 1.58 ENSDART00000052383
cd81a
CD81 molecule a
chr19_-_31341850 1.48 ENSDART00000040810
arl4ab
ADP-ribosylation factor-like 4ab
chr14_-_15171435 1.48 ENSDART00000159148
ENSDART00000166622
si:dkey-77g12.1
si:dkey-77g12.1
chr20_-_51697437 1.46 ENSDART00000145391
si:ch211-14a11.2
si:ch211-14a11.2
chr22_-_34872533 1.46 ENSDART00000167176
slit1b
slit homolog 1b (Drosophila)
chr10_+_45345574 1.46 ENSDART00000166085
ppiab
peptidylprolyl isomerase Ab (cyclophilin A)
chr5_-_68022631 1.46 ENSDART00000143199
wasf3a
WAS protein family, member 3a
chr16_+_11029762 1.41 ENSDART00000091183
erfl3
Ets2 repressor factor like 3
chr3_+_40809011 1.40 ENSDART00000033713
arpc1b
actin related protein 2/3 complex, subunit 1B
chr16_+_51180938 1.40 ENSDART00000169022
hmgn2
high mobility group nucleosomal binding domain 2
chr3_+_40315410 1.39 ENSDART00000083241
ENSDART00000132827
slc29a4
solute carrier family 29 (equilibrative nucleoside transporter), member 4
chr3_+_14388010 1.36 ENSDART00000171726
ENSDART00000165452
tmem56b
transmembrane protein 56b
chr2_+_26288301 1.36 ENSDART00000017668
ptbp1a
polypyrimidine tract binding protein 1a
chr2_-_17827983 1.35 ENSDART00000166518
ptprfb
protein tyrosine phosphatase, receptor type, f, b
chr13_-_37653840 1.33 ENSDART00000143806
si:dkey-188i13.11
si:dkey-188i13.11
chr24_+_26997798 1.33 ENSDART00000089506
larp4b
La ribonucleoprotein domain family, member 4B
chr12_+_695619 1.33 ENSDART00000161691
abcc3
ATP-binding cassette, sub-family C (CFTR/MRP), member 3
chr5_-_2689753 1.33 ENSDART00000172699
gng10
guanine nucleotide binding protein (G protein), gamma 10
chr17_-_6599484 1.33 ENSDART00000156927
ANKRD66
si:ch211-189e2.2
chr10_+_10351685 1.31 ENSDART00000109432
cercam
cerebral endothelial cell adhesion molecule
chr22_-_367569 1.31 ENSDART00000041895
ssu72
SSU72 homolog, RNA polymerase II CTD phosphatase
chr16_+_40575742 1.30 ENSDART00000161503
ccne2
cyclin E2
chr8_+_8298439 1.29 ENSDART00000170566
srpk3
SRSF protein kinase 3
chr19_+_636886 1.28 ENSDART00000149192
tert
telomerase reverse transcriptase
chr1_-_411331 1.28 ENSDART00000092524
rasa3
RAS p21 protein activator 3
chr3_-_32180796 1.27 ENSDART00000133191
ENSDART00000055308
pih1d1
PIH1 domain containing 1
chr25_+_37348730 1.26 ENSDART00000156639
pamr1
peptidase domain containing associated with muscle regeneration 1
chr2_-_17828279 1.24 ENSDART00000083314
ptprfb
protein tyrosine phosphatase, receptor type, f, b
chr14_-_36863432 1.23 ENSDART00000158052
rnf130
ring finger protein 130
chr18_+_33788340 1.23 ENSDART00000136950
si:dkey-145c18.2
si:dkey-145c18.2
chr20_+_1398564 1.23 ENSDART00000002242
leg1.2
liver-enriched gene 1, tandem duplicate 2
chr12_+_13282797 1.23 ENSDART00000137757
ENSDART00000152397
irf9
interferon regulatory factor 9
chr12_-_212843 1.22 ENSDART00000083574
CABZ01102039.1

chr23_+_9560991 1.21 ENSDART00000081433
ENSDART00000131594
ENSDART00000130069
ENSDART00000138601
adrm1
adhesion regulating molecule 1
chr7_+_38510197 1.21 ENSDART00000173468
ENSDART00000100479
slc7a9
solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9
chr3_+_1211242 1.20 ENSDART00000171287
ENSDART00000165769
poldip3
polymerase (DNA-directed), delta interacting protein 3
chr20_+_27298783 1.19 ENSDART00000013861
ppp4r4
protein phosphatase 4, regulatory subunit 4
chr22_-_16180849 1.19 ENSDART00000090390
vcam1b
vascular cell adhesion molecule 1b
chr23_+_9560797 1.19 ENSDART00000180014
adrm1
adhesion regulating molecule 1
chr16_-_21668082 1.15 ENSDART00000088513
gnl1
guanine nucleotide binding protein-like 1
chr5_-_12093618 1.15 ENSDART00000161542
lrrc74b
leucine rich repeat containing 74B
chr5_-_69523816 1.14 ENSDART00000112692
si:ch211-157p22.10
si:ch211-157p22.10
chr8_+_14158021 1.12 ENSDART00000080832
si:dkey-6n6.2
si:dkey-6n6.2
chr7_+_20563305 1.10 ENSDART00000169661
si:dkey-19b23.10
si:dkey-19b23.10
chr15_+_3284684 1.09 ENSDART00000179778
foxo1a
forkhead box O1 a
chr16_-_12173554 1.08 ENSDART00000110567
ENSDART00000155935
clstn3
calsyntenin 3
chr13_-_438705 1.07 ENSDART00000082142
CU570800.1

chr8_-_52859301 1.07 ENSDART00000162004
nr5a1a
nuclear receptor subfamily 5, group A, member 1a
chr4_+_1600034 1.06 ENSDART00000146779
slc38a2
solute carrier family 38, member 2
chr25_-_16146851 1.06 ENSDART00000104043
dkk3b
dickkopf WNT signaling pathway inhibitor 3b
chr20_-_45661049 1.05 ENSDART00000124582
ENSDART00000131251
napbb
N-ethylmaleimide-sensitive factor attachment protein, beta b
chr10_+_15777064 1.05 ENSDART00000114483
apba1b
amyloid beta (A4) precursor protein-binding, family A, member 1b
chr6_+_21740672 1.04 ENSDART00000193734
lhfpl4a
lipoma HMGIC fusion partner-like 4a
chr19_+_935565 1.03 ENSDART00000113368
RNF5
ring finger protein 5
chr21_+_11415224 1.02 ENSDART00000049036
zgc:92275
zgc:92275
chr6_+_2093367 1.02 ENSDART00000148396
tgm2b
transglutaminase 2b
chr20_+_13894123 1.01 ENSDART00000007744
slc30a1a
solute carrier family 30 (zinc transporter), member 1a
chr11_-_4302251 1.00 ENSDART00000182554
CT033790.1

chr10_+_40583930 0.98 ENSDART00000134523
taar18j
trace amine associated receptor 18j
chr23_+_44307996 0.98 ENSDART00000042430
dlg4b
discs, large homolog 4b (Drosophila)
chr11_+_1796426 0.98 ENSDART00000173330
lrp1aa
low density lipoprotein receptor-related protein 1Aa
chr5_+_483965 0.97 ENSDART00000150007
tek
TEK tyrosine kinase, endothelial
chr13_+_51853716 0.97 ENSDART00000175341
ENSDART00000187855
LT631684.1

chr11_+_30161168 0.97 ENSDART00000157385
cdkl5
cyclin-dependent kinase-like 5
chr16_-_12512568 0.97 ENSDART00000055161
ENSDART00000160906
cox6b2
cytochrome c oxidase subunit VIb polypeptide 2
chr5_-_46273938 0.97 ENSDART00000080033
si:ch211-130m23.3
si:ch211-130m23.3
chr13_-_18069421 0.97 ENSDART00000146772
ENSDART00000134477
zfand4
zinc finger, AN1-type domain 4
chr12_-_20303438 0.95 ENSDART00000153057
rhbdf1b
rhomboid 5 homolog 1b (Drosophila)
chr12_+_2522642 0.95 ENSDART00000152567
frmpd2
FERM and PDZ domain containing 2
chr8_-_15292197 0.94 ENSDART00000140867
spata6
spermatogenesis associated 6
chr15_+_3284416 0.94 ENSDART00000187665
ENSDART00000171723
foxo1a
forkhead box O1 a
chr14_+_29769336 0.93 ENSDART00000105898
si:dkey-34l15.1
si:dkey-34l15.1
chr25_+_34013093 0.93 ENSDART00000011967
anxa2a
annexin A2a
chr18_+_30028135 0.93 ENSDART00000140825
ENSDART00000145306
ENSDART00000136810
si:ch211-220f16.1
si:ch211-220f16.1
chr9_+_3035128 0.93 ENSDART00000140693
si:ch211-173m16.2
si:ch211-173m16.2
chr12_+_499881 0.92 ENSDART00000167527
mprip
myosin phosphatase Rho interacting protein
chr25_+_34915576 0.90 ENSDART00000073441
sntb2
syntrophin, beta 2
chr16_-_12173399 0.89 ENSDART00000142574
clstn3
calsyntenin 3
chr4_+_16710001 0.89 ENSDART00000035899
pkp2
plakophilin 2
chr17_+_53311618 0.87 ENSDART00000166517
asb2b
ankyrin repeat and SOCS box containing 2b
chr15_+_42397125 0.86 ENSDART00000169751
tiam1b
T cell lymphoma invasion and metastasis 1b
chr5_-_52784152 0.85 ENSDART00000169307
fam189a2
family with sequence similarity 189, member A2
chr25_-_23526058 0.85 ENSDART00000191331
ENSDART00000062930
phlda2
pleckstrin homology-like domain, family A, member 2
chr1_-_59417949 0.85 ENSDART00000170558
si:ch211-188p14.3
si:ch211-188p14.3
chr24_+_42131564 0.84 ENSDART00000153854
wwp1
WW domain containing E3 ubiquitin protein ligase 1
chr24_+_42127983 0.83 ENSDART00000190157
ENSDART00000176032
ENSDART00000175790
wwp1
WW domain containing E3 ubiquitin protein ligase 1
chr7_+_41340520 0.83 ENSDART00000005127
garem
GRB2 associated, regulator of MAPK1
chr20_-_54381034 0.83 ENSDART00000136779
entpd5b
ectonucleoside triphosphate diphosphohydrolase 5b
chr1_-_59176949 0.82 ENSDART00000128742
CABZ01118678.1

chr20_-_5369105 0.82 ENSDART00000114316
sptlc2b
serine palmitoyltransferase, long chain base subunit 2b
chr1_+_55293424 0.82 ENSDART00000152464
zgc:172106
zgc:172106
chr6_-_15604157 0.81 ENSDART00000141597
lrrfip1b
leucine rich repeat (in FLII) interacting protein 1b
chr10_-_27196093 0.81 ENSDART00000185282
auts2a
autism susceptibility candidate 2a
chr13_+_36633355 0.81 ENSDART00000135612
si:ch211-67f24.7
si:ch211-67f24.7
chr3_+_24537023 0.81 ENSDART00000077702
sp100.1
SP110 nuclear body protein, tandem duplicate 1
chr14_+_15495088 0.80 ENSDART00000165765
ENSDART00000188577
si:dkey-203a12.6
si:dkey-203a12.6
chr21_-_7882905 0.80 ENSDART00000056561
s100z
S100 calcium binding protein Z
chr11_+_3254524 0.80 ENSDART00000159459
pmela
premelanosome protein a
chr25_+_34915762 0.80 ENSDART00000191776
sntb2
syntrophin, beta 2
chr21_+_103194 0.80 ENSDART00000162755
zer1
zyg-11 related, cell cycle regulator
chr13_+_25486608 0.79 ENSDART00000057689
bag3
BCL2 associated athanogene 3
chr11_-_236766 0.79 ENSDART00000163978
dusp7
dual specificity phosphatase 7
chr8_+_53051701 0.78 ENSDART00000131514
nadka
NAD kinase a
chr22_-_16180467 0.78 ENSDART00000171331
ENSDART00000185607
vcam1b
vascular cell adhesion molecule 1b
chr11_+_40306579 0.77 ENSDART00000167504
si:dkey-207b20.2
si:dkey-207b20.2
chr11_+_3254252 0.76 ENSDART00000123568
pmela
premelanosome protein a
chr1_-_46632948 0.74 ENSDART00000148893
ENSDART00000053232
cdadc1
cytidine and dCMP deaminase domain containing 1
chr4_-_9852318 0.74 ENSDART00000080702
glt8d2
glycosyltransferase 8 domain containing 2
chr18_-_3166726 0.74 ENSDART00000165002
aqp11
aquaporin 11
chr15_-_23793641 0.74 ENSDART00000122891
tmem97
transmembrane protein 97
chr22_+_4707663 0.74 ENSDART00000042194
cers4a
ceramide synthase 4a
chr23_+_44374041 0.73 ENSDART00000136056
ephb4b
eph receptor B4b
chr12_+_18782821 0.73 ENSDART00000152918
mkl1b
megakaryoblastic leukemia (translocation) 1b
chr18_+_5490668 0.73 ENSDART00000167035
mibp2
muscle-specific beta 1 integrin binding protein 2
chr3_+_36284986 0.73 ENSDART00000059533
wipi1
WD repeat domain, phosphoinositide interacting 1
chr14_+_48960078 0.73 ENSDART00000165514
mif
macrophage migration inhibitory factor
chr14_+_15257658 0.73 ENSDART00000161625
ENSDART00000193577
si:dkey-77g12.4
si:dkey-203a12.5
si:dkey-77g12.4
si:dkey-203a12.5
chr18_+_16246806 0.72 ENSDART00000142584
alx1
ALX homeobox 1
chr7_-_7845540 0.72 ENSDART00000166280
cxcl8b.1
chemokine (C-X-C motif) ligand 8b, duplicate 1
chr10_+_6884123 0.71 ENSDART00000149095
ENSDART00000148772
ENSDART00000149334
ddx4
DEAD (Asp-Glu-Ala-Asp) box polypeptide 4
chr7_+_25053331 0.71 ENSDART00000173998
si:dkey-23i12.7
si:dkey-23i12.7
chr2_+_21486529 0.71 ENSDART00000047468
inhbab
inhibin, beta Ab
chr11_-_236984 0.71 ENSDART00000170778
dusp7
dual specificity phosphatase 7
chr9_-_23891102 0.70 ENSDART00000186799
asb18
ankyrin repeat and SOCS box containing 18
chr9_-_9671244 0.70 ENSDART00000018228
gsk3b
glycogen synthase kinase 3 beta
chr3_-_27601544 0.68 ENSDART00000188201
zgc:66160
zgc:66160
chr22_-_50878 0.67 ENSDART00000166132
CABZ01085140.1

chr5_+_22969651 0.67 ENSDART00000089992
ENSDART00000145477
hmgn7
high mobility group nucleosomal binding domain 7
chr13_+_33055548 0.66 ENSDART00000137315
rdh12
retinol dehydrogenase 12 (all-trans/9-cis/11-cis)
chr8_-_53490376 0.66 ENSDART00000158789
chdh
choline dehydrogenase
chr14_+_30910114 0.66 ENSDART00000187166
ENSDART00000078187
foxo4
forkhead box O4
chr22_+_6905210 0.66 ENSDART00000167530
CABZ01065328.2

chr14_-_21218891 0.66 ENSDART00000158294
ppp2r2cb
protein phosphatase 2, regulatory subunit B, gamma b
chr5_+_51443009 0.66 ENSDART00000083350
rasgrf2b
Ras protein-specific guanine nucleotide-releasing factor 2b
chr8_+_2456854 0.66 ENSDART00000133938
ENSDART00000002764
polb
polymerase (DNA directed), beta
chr25_-_8602437 0.65 ENSDART00000171200
rhcgb
Rh family, C glycoprotein b
chrM_+_9735 0.65 ENSDART00000093613
mt-co3
cytochrome c oxidase III, mitochondrial
chr16_+_28754403 0.64 ENSDART00000103340
s100v1
S100 calcium binding protein V1
chr3_-_30061985 0.64 ENSDART00000189583
ppfia3
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
chr20_-_53366137 0.64 ENSDART00000146001
wasf1
WAS protein family, member 1
chr20_+_16173618 0.64 ENSDART00000192109
ENSDART00000104112
ENSDART00000129633
zyg11
zyg-11 homolog (C. elegans)
chr11_+_41560792 0.63 ENSDART00000127292
kcnab2a
potassium voltage-gated channel, shaker-related subfamily, beta member 2 a
chr6_+_40661703 0.62 ENSDART00000142492
eno1b
enolase 1b, (alpha)
chr1_-_44940830 0.62 ENSDART00000097500
ENSDART00000134464
ENSDART00000137216
tmem176
transmembrane protein 176
chr1_-_59571758 0.61 ENSDART00000193546
ENSDART00000167087
wfikkn1
WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1
chr5_+_36513605 0.61 ENSDART00000013590
wnt11
wingless-type MMTV integration site family, member 11
chr1_-_19845378 0.61 ENSDART00000139314
ENSDART00000132958
ENSDART00000147502
grhprb
glyoxylate reductase/hydroxypyruvate reductase b
chr17_+_30587333 0.61 ENSDART00000156500
nhsl1a
NHS-like 1a
chr4_+_70556298 0.58 ENSDART00000170985
si:dkey-11d20.1
si:dkey-11d20.1
chr21_+_7900107 0.58 ENSDART00000056560
ch25hl2
cholesterol 25-hydroxylase like 2
chr3_+_62217479 0.58 ENSDART00000175012
BX470259.4

chr6_-_15604417 0.58 ENSDART00000157817
lrrfip1b
leucine rich repeat (in FLII) interacting protein 1b
chr4_+_39742119 0.57 ENSDART00000176004
CR749167.2

chr2_-_48966431 0.57 ENSDART00000147948
kcnj9
potassium inwardly-rectifying channel, subfamily J, member 9
chr8_+_23436411 0.56 ENSDART00000140044
foxp3b
forkhead box P3b
chr9_-_2573121 0.56 ENSDART00000181340
scrn3
secernin 3
chr15_+_1397811 0.56 ENSDART00000102125
schip1
schwannomin interacting protein 1
chr24_+_35564668 0.56 ENSDART00000122734
cebpd
CCAAT/enhancer binding protein (C/EBP), delta
chr4_-_12914163 0.55 ENSDART00000140002
ENSDART00000145917
ENSDART00000141355
ENSDART00000067135
msrb3
methionine sulfoxide reductase B3
chr7_+_26173751 0.55 ENSDART00000065131
si:ch211-196f2.7
si:ch211-196f2.7
chr19_-_617246 0.55 ENSDART00000062551
cyp51
cytochrome P450, family 51
chr14_+_36220479 0.54 ENSDART00000148319
pitx2
paired-like homeodomain 2
chr24_+_37406535 0.54 ENSDART00000138264
si:ch211-183d21.1
si:ch211-183d21.1
chr5_-_67911111 0.54 ENSDART00000051833
gsx1
GS homeobox 1
chr18_+_33762090 0.54 ENSDART00000147605
si:dkey-145c18.4
si:dkey-145c18.4
chr9_-_8454060 0.54 ENSDART00000110158
irs2b
insulin receptor substrate 2b
chr7_+_7048245 0.53 ENSDART00000001649
actn3b
actinin alpha 3b
chr11_-_44347587 0.53 ENSDART00000172919
si:cabz01100188.1
si:cabz01100188.1
chr3_-_27601812 0.53 ENSDART00000077734
zgc:66160
zgc:66160
chr3_-_61185746 0.53 ENSDART00000028219
pvalb4
parvalbumin 4

Network of associatons between targets according to the STRING database.

First level regulatory network of egr2a+egr2b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 4.6 GO:0009396 folic acid-containing compound biosynthetic process(GO:0009396)
0.6 1.7 GO:0002369 T cell cytokine production(GO:0002369)
0.5 1.6 GO:0097435 fibril organization(GO:0097435)
0.4 1.3 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.4 1.3 GO:0007571 age-dependent general metabolic decline(GO:0007571)
0.4 1.1 GO:1990359 detoxification of zinc ion(GO:0010312) stress response to zinc ion(GO:1990359)
0.3 1.4 GO:0060468 negative regulation of fertilization(GO:0060467) prevention of polyspermy(GO:0060468) cortical granule exocytosis(GO:0060471)
0.3 3.0 GO:0098787 mRNA cleavage involved in mRNA processing(GO:0098787) pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.3 1.0 GO:0097113 AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688)
0.3 0.9 GO:1904969 bleb assembly(GO:0032060) slow muscle cell migration(GO:1904969)
0.3 1.8 GO:0010799 regulation of peptidyl-threonine phosphorylation(GO:0010799) negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.3 2.0 GO:0048745 smooth muscle tissue development(GO:0048745)
0.3 2.6 GO:0097374 sensory neuron axon guidance(GO:0097374)
0.3 1.1 GO:0010807 regulation of synaptic vesicle priming(GO:0010807)
0.3 0.8 GO:0010660 negative regulation of muscle cell apoptotic process(GO:0010656) muscle cell apoptotic process(GO:0010657) striated muscle cell apoptotic process(GO:0010658) regulation of muscle cell apoptotic process(GO:0010660) regulation of striated muscle cell apoptotic process(GO:0010662) negative regulation of striated muscle cell apoptotic process(GO:0010664)
0.3 1.0 GO:0072578 neurotransmitter-gated ion channel clustering(GO:0072578) gamma-aminobutyric acid receptor clustering(GO:0097112)
0.2 1.9 GO:0046146 tetrahydrobiopterin biosynthetic process(GO:0006729) pteridine-containing compound biosynthetic process(GO:0042559) tetrahydrobiopterin metabolic process(GO:0046146)
0.2 0.7 GO:0019695 choline metabolic process(GO:0019695)
0.2 2.0 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.2 1.9 GO:0046546 development of primary male sexual characteristics(GO:0046546)
0.2 1.3 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.2 0.5 GO:0031630 regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
0.2 2.4 GO:0043248 proteasome assembly(GO:0043248)
0.2 1.7 GO:0061718 glucose catabolic process(GO:0006007) NADH regeneration(GO:0006735) glycolytic process through fructose-6-phosphate(GO:0061615) glycolytic process through glucose-6-phosphate(GO:0061620) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.1 0.7 GO:0010718 positive regulation of epithelial to mesenchymal transition(GO:0010718)
0.1 0.8 GO:0098957 anterograde axonal transport of mitochondrion(GO:0098957)
0.1 2.1 GO:2000601 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.1 0.6 GO:0030091 protein repair(GO:0030091)
0.1 2.7 GO:0002574 thrombocyte differentiation(GO:0002574)
0.1 0.6 GO:0097272 ammonia homeostasis(GO:0097272)
0.1 0.9 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.1 0.9 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.1 0.1 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.1 0.7 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.1 0.5 GO:0021828 pallium development(GO:0021543) cerebral cortex cell migration(GO:0021795) cerebral cortex tangential migration(GO:0021800) cerebral cortex tangential migration using cell-axon interactions(GO:0021824) substrate-dependent cerebral cortex tangential migration(GO:0021825) gonadotrophin-releasing hormone neuronal migration to the hypothalamus(GO:0021828) hypothalamic tangential migration using cell-axon interactions(GO:0021856) cerebral cortex development(GO:0021987)
0.1 0.5 GO:0015803 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.1 0.8 GO:0006741 NADP biosynthetic process(GO:0006741)
0.1 0.5 GO:0061072 iris morphogenesis(GO:0061072)
0.1 1.5 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 1.1 GO:0006868 glutamine transport(GO:0006868)
0.1 0.3 GO:0035751 regulation of lysosomal lumen pH(GO:0035751)
0.1 0.6 GO:0035332 positive regulation of hippo signaling(GO:0035332)
0.1 1.4 GO:1901642 nucleoside transport(GO:0015858) nucleoside transmembrane transport(GO:1901642)
0.1 2.3 GO:0006094 gluconeogenesis(GO:0006094)
0.1 1.8 GO:0014823 response to activity(GO:0014823)
0.1 0.3 GO:0032207 regulation of telomere maintenance via recombination(GO:0032207) negative regulation of telomere maintenance via recombination(GO:0032208)
0.1 0.5 GO:2000580 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.1 0.5 GO:0006699 bile acid biosynthetic process(GO:0006699) bile acid metabolic process(GO:0008206)
0.1 0.6 GO:0032889 regulation of vacuole fusion, non-autophagic(GO:0032889)
0.1 0.3 GO:0097037 heme export(GO:0097037)
0.1 1.1 GO:0030325 adrenal gland development(GO:0030325)
0.1 0.1 GO:0072045 convergent extension involved in nephron morphogenesis(GO:0072045)
0.1 0.8 GO:0034312 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.1 0.1 GO:0032369 negative regulation of lipid transport(GO:0032369)
0.1 1.2 GO:0009134 nucleoside diphosphate catabolic process(GO:0009134)
0.1 0.7 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.1 0.3 GO:0006526 arginine biosynthetic process(GO:0006526)
0.1 0.4 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.1 0.4 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.1 0.4 GO:0032367 intracellular cholesterol transport(GO:0032367)
0.1 1.0 GO:0051897 positive regulation of protein kinase B signaling(GO:0051897)
0.1 0.7 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.1 0.1 GO:0021572 rhombomere 5 development(GO:0021571) rhombomere 6 development(GO:0021572)
0.1 0.6 GO:0098900 regulation of action potential(GO:0098900)
0.1 0.2 GO:0045724 positive regulation of cilium assembly(GO:0045724)
0.1 0.2 GO:0021530 spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.1 1.0 GO:0018149 peptide cross-linking(GO:0018149)
0.1 0.2 GO:0044333 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
0.1 0.3 GO:0002159 desmosome assembly(GO:0002159)
0.0 0.6 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.7 GO:0008406 gonad development(GO:0008406)
0.0 0.3 GO:1903306 negative regulation of calcium ion-dependent exocytosis(GO:0045955) negative regulation of regulated secretory pathway(GO:1903306)
0.0 1.5 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.4 GO:0021754 facial nucleus development(GO:0021754)
0.0 0.5 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.0 0.1 GO:1903587 regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903587) positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903589)
0.0 3.5 GO:0055113 epiboly involved in gastrulation with mouth forming second(GO:0055113)
0.0 0.2 GO:0089700 protein kinase D signaling(GO:0089700)
0.0 0.2 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.0 1.5 GO:0021602 cranial nerve morphogenesis(GO:0021602)
0.0 0.5 GO:0018057 peptidyl-lysine oxidation(GO:0018057)
0.0 0.2 GO:0030859 polarized epithelial cell differentiation(GO:0030859)
0.0 0.4 GO:0072498 embryonic skeletal joint development(GO:0072498)
0.0 0.9 GO:0045773 positive regulation of axon extension(GO:0045773)
0.0 0.8 GO:0021884 forebrain neuron development(GO:0021884)
0.0 2.4 GO:0001946 lymphangiogenesis(GO:0001946)
0.0 0.4 GO:1902041 regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902041) negative regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902042)
0.0 0.4 GO:0006382 adenosine to inosine editing(GO:0006382)
0.0 0.1 GO:0070316 G0 to G1 transition(GO:0045023) regulation of G0 to G1 transition(GO:0070316) negative regulation of G0 to G1 transition(GO:0070317)
0.0 0.3 GO:0042664 negative regulation of endodermal cell fate specification(GO:0042664) negative regulation of endodermal cell differentiation(GO:1903225)
0.0 0.5 GO:0007413 axonal fasciculation(GO:0007413)
0.0 4.5 GO:0016579 protein deubiquitination(GO:0016579)
0.0 0.5 GO:0051967 negative regulation of cytosolic calcium ion concentration(GO:0051481) negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 0.2 GO:0099612 protein localization to juxtaparanode region of axon(GO:0071205) protein localization to axon(GO:0099612)
0.0 0.2 GO:0003261 cardiac muscle progenitor cell migration to the midline involved in heart field formation(GO:0003261)
0.0 0.1 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
0.0 0.3 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.0 1.6 GO:0007062 sister chromatid cohesion(GO:0007062)
0.0 0.7 GO:1903670 regulation of sprouting angiogenesis(GO:1903670)
0.0 0.7 GO:0070831 basement membrane assembly(GO:0070831)
0.0 1.1 GO:0016126 sterol biosynthetic process(GO:0016126)
0.0 0.1 GO:0090230 regulation of centromere complex assembly(GO:0090230) regulation of kinetochore assembly(GO:0090234)
0.0 0.5 GO:0030168 platelet activation(GO:0030168)
0.0 0.7 GO:0006303 double-strand break repair via nonhomologous end joining(GO:0006303)
0.0 1.7 GO:0033339 pectoral fin development(GO:0033339)
0.0 0.9 GO:0050708 regulation of protein secretion(GO:0050708)
0.0 0.1 GO:0071276 cellular response to cadmium ion(GO:0071276)
0.0 0.7 GO:0060117 auditory receptor cell development(GO:0060117)
0.0 0.3 GO:0032264 IMP salvage(GO:0032264)
0.0 0.1 GO:0030299 intestinal cholesterol absorption(GO:0030299)
0.0 0.9 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 0.9 GO:0050772 positive regulation of axonogenesis(GO:0050772)
0.0 0.4 GO:0031114 regulation of microtubule depolymerization(GO:0031114)
0.0 0.2 GO:0050732 negative regulation of peptidyl-tyrosine phosphorylation(GO:0050732) negative regulation of protein tyrosine kinase activity(GO:0061099)
0.0 0.7 GO:0061077 chaperone-mediated protein folding(GO:0061077)
0.0 1.0 GO:0000082 G1/S transition of mitotic cell cycle(GO:0000082)
0.0 1.7 GO:0045732 positive regulation of protein catabolic process(GO:0045732)
0.0 0.7 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.0 0.1 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.5 GO:0002027 regulation of heart rate(GO:0002027)
0.0 0.4 GO:0019835 cytolysis(GO:0019835)
0.0 1.2 GO:0070121 Kupffer's vesicle development(GO:0070121)
0.0 0.1 GO:0061551 trigeminal ganglion development(GO:0061551)
0.0 0.3 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.1 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.4 GO:0032526 response to retinoic acid(GO:0032526)
0.0 0.1 GO:0030216 keratinocyte differentiation(GO:0030216)
0.0 0.4 GO:0060319 primitive erythrocyte differentiation(GO:0060319)
0.0 0.4 GO:0006306 DNA alkylation(GO:0006305) DNA methylation(GO:0006306)
0.0 0.2 GO:0097178 ruffle assembly(GO:0097178)
0.0 0.4 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.0 0.6 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.0 0.4 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.0 0.3 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.0 0.1 GO:0006267 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.0 0.2 GO:0051496 positive regulation of stress fiber assembly(GO:0051496)
0.0 0.2 GO:0007198 adenylate cyclase-inhibiting serotonin receptor signaling pathway(GO:0007198)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0000333 telomerase catalytic core complex(GO:0000333)
0.3 1.0 GO:0060077 inhibitory synapse(GO:0060077)
0.3 1.3 GO:0097134 cyclin E1-CDK2 complex(GO:0097134)
0.3 1.0 GO:0032839 dendrite cytoplasm(GO:0032839)
0.3 1.3 GO:0097255 R2TP complex(GO:0097255)
0.3 4.3 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.3 1.1 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.2 2.4 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.2 0.9 GO:0097224 sperm connecting piece(GO:0097224)
0.2 1.7 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.1 2.1 GO:0031209 SCAR complex(GO:0031209)
0.1 1.0 GO:0031211 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.1 1.4 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.1 0.7 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.1 1.3 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.1 0.6 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 1.7 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1 0.4 GO:0097433 dense body(GO:0097433)
0.1 0.9 GO:0014704 intercalated disc(GO:0014704)
0.1 1.6 GO:0008278 cohesin complex(GO:0008278)
0.1 1.2 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.6 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.3 GO:0070062 extracellular exosome(GO:0070062)
0.0 1.8 GO:0005861 troponin complex(GO:0005861)
0.0 0.4 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.0 1.6 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 0.6 GO:0045277 respiratory chain complex IV(GO:0045277)
0.0 1.0 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.5 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.4 GO:0043209 myelin sheath(GO:0043209)
0.0 0.3 GO:0045095 keratin filament(GO:0045095)
0.0 0.2 GO:0033010 paranodal junction(GO:0033010)
0.0 0.3 GO:0070187 telosome(GO:0070187)
0.0 0.2 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 0.7 GO:0043186 P granule(GO:0043186)
0.0 1.7 GO:0005814 centriole(GO:0005814)
0.0 1.5 GO:0008287 protein serine/threonine phosphatase complex(GO:0008287) phosphatase complex(GO:1903293)
0.0 0.6 GO:0043679 axon terminus(GO:0043679)
0.0 0.3 GO:0043189 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 0.3 GO:0030057 desmosome(GO:0030057)
0.0 0.1 GO:0035517 PR-DUB complex(GO:0035517)
0.0 0.2 GO:0005869 dynactin complex(GO:0005869)
0.0 0.5 GO:0098978 glutamatergic synapse(GO:0098978)
0.0 0.1 GO:0005922 connexon complex(GO:0005922)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0003721 telomerase RNA reverse transcriptase activity(GO:0003721)
0.4 2.4 GO:0061133 endopeptidase activator activity(GO:0061133)
0.3 1.3 GO:0050211 procollagen galactosyltransferase activity(GO:0050211)
0.3 0.9 GO:0032027 myosin light chain binding(GO:0032027)
0.3 2.2 GO:0016803 ether hydrolase activity(GO:0016803)
0.2 2.1 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.2 1.1 GO:0039706 co-receptor binding(GO:0039706)
0.2 1.0 GO:0070004 cysteine-type exopeptidase activity(GO:0070004)
0.2 0.6 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.2 0.7 GO:0005153 interleukin-8 receptor binding(GO:0005153)
0.2 1.1 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.2 1.4 GO:0008504 monoamine transmembrane transporter activity(GO:0008504)
0.2 2.3 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.2 1.7 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.1 0.9 GO:0019215 intermediate filament binding(GO:0019215)
0.1 1.0 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1 0.4 GO:0001160 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160)
0.1 3.2 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.1 1.5 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.1 0.7 GO:0004126 cytidine deaminase activity(GO:0004126)
0.1 0.7 GO:0050262 ribosylnicotinamide kinase activity(GO:0050262)
0.1 0.4 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 2.1 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.1 0.4 GO:0030228 lipoprotein particle receptor activity(GO:0030228)
0.1 0.6 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.1 1.5 GO:0016018 cyclosporin A binding(GO:0016018)
0.1 1.1 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.1 0.3 GO:0016743 carboxyl- or carbamoyltransferase activity(GO:0016743)
0.1 0.5 GO:0004966 galanin receptor activity(GO:0004966)
0.1 0.6 GO:0000254 C-4 methylsterol oxidase activity(GO:0000254)
0.1 1.0 GO:0004859 phospholipase inhibitor activity(GO:0004859) lipase inhibitor activity(GO:0055102)
0.1 0.8 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.1 0.6 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 1.9 GO:0051018 protein kinase A binding(GO:0051018)
0.1 0.4 GO:0098973 structural constituent of postsynaptic actin cytoskeleton(GO:0098973)
0.1 1.2 GO:0045134 guanosine-diphosphatase activity(GO:0004382) uridine-diphosphatase activity(GO:0045134)
0.1 0.3 GO:0070052 collagen V binding(GO:0070052)
0.1 4.6 GO:0016879 ligase activity, forming carbon-nitrogen bonds(GO:0016879)
0.1 0.6 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1 1.3 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.1 0.3 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.1 0.3 GO:0003964 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.1 0.4 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.1 0.3 GO:0004619 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619)
0.1 1.7 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.1 0.5 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.1 1.0 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.1 0.3 GO:0034046 poly(G) binding(GO:0034046)
0.0 0.7 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.6 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.6 GO:0031628 opioid receptor binding(GO:0031628)
0.0 1.1 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.3 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.9 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.1 GO:1901612 cardiolipin binding(GO:1901612)
0.0 1.1 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 1.0 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.0 0.4 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 0.3 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.3 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 4.5 GO:0036459 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 0.6 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.0 0.2 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
0.0 0.7 GO:0005003 ephrin receptor activity(GO:0005003)
0.0 0.1 GO:0003868 4-hydroxyphenylpyruvate dioxygenase activity(GO:0003868)
0.0 0.7 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.5 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.5 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 1.0 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 3.1 GO:0008201 heparin binding(GO:0008201)
0.0 0.6 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.0 0.4 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.7 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.1 GO:0070996 type 1 melanocortin receptor binding(GO:0070996)
0.0 0.5 GO:0030552 cAMP binding(GO:0030552)
0.0 0.4 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.1 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.0 0.2 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.0 0.3 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.3 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.8 GO:0051087 chaperone binding(GO:0051087)
0.0 0.3 GO:0005222 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) intracellular cAMP activated cation channel activity(GO:0005222) intracellular cGMP activated cation channel activity(GO:0005223) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0 0.5 GO:0048185 activin binding(GO:0048185)
0.0 0.3 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.1 GO:1990518 ATP-dependent 3'-5' DNA helicase activity(GO:0043140) single-stranded DNA-dependent ATP-dependent 3'-5' DNA helicase activity(GO:1990518)
0.0 0.6 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.3 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.5 GO:0043548 phosphatidylinositol 3-kinase binding(GO:0043548)
0.0 0.8 GO:0017022 myosin binding(GO:0017022)
0.0 1.1 GO:0015179 L-amino acid transmembrane transporter activity(GO:0015179)
0.0 0.3 GO:0031729 CCR1 chemokine receptor binding(GO:0031726) CCR4 chemokine receptor binding(GO:0031729) CCR5 chemokine receptor binding(GO:0031730)
0.0 0.4 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.1 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 0.3 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.5 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.5 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.0 0.1 GO:0004945 angiotensin type I receptor activity(GO:0001596) angiotensin type II receptor activity(GO:0004945)
0.0 0.2 GO:0005537 mannose binding(GO:0005537)
0.0 0.6 GO:0005109 frizzled binding(GO:0005109)
0.0 0.4 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.5 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 2.2 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.1 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.0 0.9 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.6 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.0 0.1 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.0 1.0 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0 0.2 GO:0043176 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0 0.1 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.1 GO:0034481 chondroitin sulfotransferase activity(GO:0034481)
0.0 0.8 GO:0008395 steroid hydroxylase activity(GO:0008395)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.2 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.1 5.3 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.1 1.3 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 1.1 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 0.7 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.8 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 1.0 PID SHP2 PATHWAY SHP2 signaling
0.0 1.2 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.2 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 0.7 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.0 1.4 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.0 0.4 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.0 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.2 1.3 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.2 1.1 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.1 0.5 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.1 1.9 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.1 2.7 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.1 0.9 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.1 1.5 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.1 0.7 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.1 1.4 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.1 0.6 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.0 1.3 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 1.2 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.5 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.6 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 1.0 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.3 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.4 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.7 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.1 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 0.3 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.0 0.6 REACTOME TELOMERE MAINTENANCE Genes involved in Telomere Maintenance
0.0 0.6 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 1.4 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.1 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.1 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.5 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.3 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.6 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels