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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for elf2a+elf2b

Z-value: 3.53

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Transcription factors associated with elf2a+elf2b

Gene Symbol Gene ID Gene Info
elf2a
ENSDARG00000019459 E74-like factor 2a (ets domain transcription factor)
elf2b
ENSDARG00000079626 E74-like factor 2b (ets domain transcription factor)
elf2b
ENSDARG00000117064 E74-like factor 2b (ets domain transcription factor)

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
elf2adr11_v1_chr14_-_46070802_46070802-0.863.8e-06Click!
elf2bdr11_v1_chr1_-_13964284_13964284-0.681.9e-03Click!

Activity profile of elf2a+elf2b motif

Sorted Z-values of elf2a+elf2b motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr10_+_44363195 10.28 ENSDART00000161744
kmt5aa
lysine methyltransferase 5Aa
chr20_-_23253630 9.41 ENSDART00000103365
ociad1
OCIA domain containing 1
chr9_+_2041535 8.28 ENSDART00000093187
lnpa
limb and neural patterns a
chr5_+_3891485 8.15 ENSDART00000129329
ENSDART00000091711
rpain
RPA interacting protein
chr12_-_3840664 8.15 ENSDART00000160967
taok2b
TAO kinase 2b
chr9_+_426392 7.60 ENSDART00000172515
bzw1b
basic leucine zipper and W2 domains 1b
chr1_-_34447515 7.57 ENSDART00000143048
lmo7b
LIM domain 7b
chr1_+_54737353 7.40 ENSDART00000130675
ENSDART00000162075
pi4k2a
phosphatidylinositol 4-kinase type 2 alpha
chr15_+_24737599 7.29 ENSDART00000078024
crk
v-crk avian sarcoma virus CT10 oncogene homolog
chr14_-_26482096 7.18 ENSDART00000187280
smad5
SMAD family member 5
chr21_-_4793686 6.88 ENSDART00000158232
notch1a
notch 1a
chr14_+_32918484 6.60 ENSDART00000105721
lnx2b
ligand of numb-protein X 2b
chr20_+_46572550 6.55 ENSDART00000139051
ENSDART00000161320
batf
basic leucine zipper transcription factor, ATF-like
chr3_+_18795570 6.51 ENSDART00000042368
fahd1
fumarylacetoacetate hydrolase domain containing 1
chr13_-_18691041 6.45 ENSDART00000057867
sfxn3
sideroflexin 3
chr25_+_186583 6.43 ENSDART00000161504
pclaf
PCNA clamp associated factor
chr6_+_33931740 6.41 ENSDART00000130492
ENSDART00000151213
orc1
origin recognition complex, subunit 1
chr13_-_35761266 6.40 ENSDART00000190217
erlec1
endoplasmic reticulum lectin 1
chr14_-_32876280 6.39 ENSDART00000173168
si:rp71-46j2.7
si:rp71-46j2.7
chr5_+_27404946 6.35 ENSDART00000121886
ENSDART00000005025
hdr
hematopoietic death receptor
chr19_-_11015238 6.32 ENSDART00000010997
tpm3
tropomyosin 3
chr13_-_35760969 6.32 ENSDART00000127476
erlec1
endoplasmic reticulum lectin 1
chr16_-_2390931 6.30 ENSDART00000149463
hace1
HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1
chr14_-_46198373 6.30 ENSDART00000031640
ENSDART00000132966
zgc:113425
zgc:113425
chr20_-_46866934 6.29 ENSDART00000158178
si:ch73-21k16.4
si:ch73-21k16.4
chr3_-_25054002 6.29 ENSDART00000086768
ep300b
E1A binding protein p300 b
chr12_-_22355430 6.12 ENSDART00000153296
ENSDART00000056919
ENSDART00000159036
nsfb
N-ethylmaleimide-sensitive factor b
chr8_+_52442622 6.06 ENSDART00000012758
zgc:77112
zgc:77112
chr25_-_19574146 6.06 ENSDART00000156811
si:ch211-59o9.10
si:ch211-59o9.10
chr7_-_51749683 6.04 ENSDART00000083190
hdac8
histone deacetylase 8
chr20_-_48898371 6.03 ENSDART00000170617
xrn2
5'-3' exoribonuclease 2
chr12_-_10508952 6.01 ENSDART00000152806
zgc:152977
zgc:152977
chr24_+_21720304 5.94 ENSDART00000147250
ENSDART00000048273
pan3
PAN3 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)
chr1_-_23294753 5.85 ENSDART00000013263
ugdh
UDP-glucose 6-dehydrogenase
chr22_-_17652914 5.85 ENSDART00000138483
si:ch73-243b8.4
si:ch73-243b8.4
chr2_-_32594777 5.69 ENSDART00000134125
fastk
Fas-activated serine/threonine kinase
chr1_+_31657842 5.64 ENSDART00000057880
poll
polymerase (DNA directed), lambda
chr8_+_47683352 5.62 ENSDART00000187320
ENSDART00000192605
dpp9
dipeptidyl-peptidase 9
chr9_-_21238159 5.61 ENSDART00000146764
ENSDART00000102143
cox17
COX17 cytochrome c oxidase copper chaperone
chr9_+_44304980 5.60 ENSDART00000147990
ssfa2
sperm specific antigen 2
chr3_+_36616713 5.60 ENSDART00000158284
pdxdc1
pyridoxal-dependent decarboxylase domain containing 1
chr4_-_1757460 5.59 ENSDART00000144074
tm7sf3
transmembrane 7 superfamily member 3
chr3_-_32337653 5.54 ENSDART00000156918
ENSDART00000156551
si:dkey-16p21.8
si:dkey-16p21.8
chr14_-_14687004 5.54 ENSDART00000169970
gcna
germ cell nuclear acidic peptidase
chr2_+_16597011 5.52 ENSDART00000160641
ENSDART00000125413
xrn1
5'-3' exoribonuclease 1
chr7_+_61764040 5.52 ENSDART00000056745
acox3
acyl-CoA oxidase 3, pristanoyl
chr17_+_17804752 5.49 ENSDART00000123350
sptlc2a
serine palmitoyltransferase, long chain base subunit 2a
chr8_+_52442785 5.49 ENSDART00000189958
zgc:77112
zgc:77112
chr9_-_20853439 5.46 ENSDART00000028247
ENSDART00000133321
gdap2
ganglioside induced differentiation associated protein 2
chr19_-_11846958 5.46 ENSDART00000148516
ctdp1
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
chr3_-_36440705 5.45 ENSDART00000162875
rogdi
rogdi homolog (Drosophila)
chr1_+_31658011 5.39 ENSDART00000192203
poll
polymerase (DNA directed), lambda
chr18_+_49969568 5.38 ENSDART00000126916
mob2b
MOB kinase activator 2b
chr20_-_54198130 5.36 ENSDART00000160409
arf6a
ADP-ribosylation factor 6a
chr5_-_19833310 5.35 ENSDART00000138186
trpv4
transient receptor potential cation channel, subfamily V, member 4
chr18_+_46162204 5.34 ENSDART00000113545
ENSDART00000147556
zgc:113340
zgc:113340
chr18_+_15271993 5.31 ENSDART00000099777
si:dkey-103i16.6
si:dkey-103i16.6
chr3_+_32416948 5.26 ENSDART00000157324
ENSDART00000154267
ENSDART00000186094
ENSDART00000155860
ENSDART00000156986
prrg2
proline rich Gla (G-carboxyglutamic acid) 2
chr5_-_29512538 5.23 ENSDART00000098364
ehmt1a
euchromatic histone-lysine N-methyltransferase 1a
chr5_-_56924747 5.21 ENSDART00000014028
ppm1db
protein phosphatase, Mg2+/Mn2+ dependent, 1Db
chr1_-_55044256 5.19 ENSDART00000165505
ENSDART00000167536
ENSDART00000170001
vps54
vacuolar protein sorting 54 homolog (S. cerevisiae)
chr15_-_28904371 5.18 ENSDART00000155154
eml2
echinoderm microtubule associated protein like 2
chr4_-_13614797 5.18 ENSDART00000138366
ENSDART00000165212
irf5
interferon regulatory factor 5
chr20_+_13141408 5.10 ENSDART00000034098
dtl
denticleless E3 ubiquitin protein ligase homolog (Drosophila)
chr2_-_57900430 5.06 ENSDART00000132245
ENSDART00000140060
si:dkeyp-68b7.7
si:dkeyp-68b7.7
chr14_-_33278084 5.05 ENSDART00000132850
stard14
START domain containing 14
chr23_-_27050083 5.04 ENSDART00000142324
ENSDART00000133249
ENSDART00000138751
ENSDART00000128718
zgc:66440
zgc:66440
chr2_-_57076687 5.03 ENSDART00000161523
slc25a42
solute carrier family 25, member 42
chr20_-_23876291 5.01 ENSDART00000043316
katna1
katanin p60 (ATPase containing) subunit A 1
chr14_-_33277743 5.00 ENSDART00000048130
stard14
START domain containing 14
chr2_+_27855346 5.00 ENSDART00000175159
ENSDART00000192645
buc
bucky ball
chr1_+_19649545 4.97 ENSDART00000054575
tmem192
transmembrane protein 192
chr12_-_26537145 4.94 ENSDART00000138437
ENSDART00000163931
ENSDART00000132737
acsf2
acyl-CoA synthetase family member 2
chr7_+_71764883 4.89 ENSDART00000166865
myl12.1
myosin, light chain 12, genome duplicate 1
chr20_-_45772306 4.89 ENSDART00000062092
trmt6
tRNA methyltransferase 6 homolog (S. cerevisiae)
chr18_+_3579829 4.88 ENSDART00000158763
ENSDART00000182850
ENSDART00000162754
ENSDART00000178789
ENSDART00000172656
lrch3
leucine-rich repeats and calponin homology (CH) domain containing 3
chr11_-_34480822 4.87 ENSDART00000129029
xxylt1
xyloside xylosyltransferase 1
chr5_-_12587053 4.86 ENSDART00000162780
vsig10
V-set and immunoglobulin domain containing 10
chr2_+_26237322 4.86 ENSDART00000030520
palm1b
paralemmin 1b
chr8_+_12951155 4.84 ENSDART00000081601
cept1a
choline/ethanolamine phosphotransferase 1a
chr20_-_48898560 4.84 ENSDART00000163071
xrn2
5'-3' exoribonuclease 2
chr16_+_36748538 4.81 ENSDART00000139069
decr1
2,4-dienoyl CoA reductase 1, mitochondrial
chr10_+_5234327 4.80 ENSDART00000133927
ENSDART00000063120
sptlc1
serine palmitoyltransferase, long chain base subunit 1
chr4_+_13931578 4.78 ENSDART00000142466
pphln1
periphilin 1
chr17_+_33415319 4.76 ENSDART00000140805
ENSDART00000025501
ENSDART00000146447
snap23.1
synaptosomal-associated protein 23.1
chr19_+_26340736 4.74 ENSDART00000013497
mylipa
myosin regulatory light chain interacting protein a
chr17_-_12498096 4.73 ENSDART00000149551
ENSDART00000105215
ENSDART00000191207
emilin1b
elastin microfibril interfacer 1b
chr4_-_13931508 4.73 ENSDART00000067174
zcrb1
zinc finger CCHC-type and RNA binding motif 1
chr20_-_32045057 4.71 ENSDART00000152970
ENSDART00000034248
rab32a
RAB32a, member RAS oncogene family
chr2_+_49457626 4.71 ENSDART00000129967
sh3gl1a
SH3-domain GRB2-like 1a
chr20_-_34028967 4.70 ENSDART00000153408
ENSDART00000033817
scyl3
SCY1-like, kinase-like 3
chr25_-_36263115 4.70 ENSDART00000143046
ENSDART00000139002
dus2
dihydrouridine synthase 2
chr11_+_25693395 4.70 ENSDART00000110224
mon1bb
MON1 secretory trafficking family member Bb
chr10_+_15024772 4.66 ENSDART00000135667
si:dkey-88l16.5
si:dkey-88l16.5
chr15_-_17138640 4.61 ENSDART00000080777
mrpl28
mitochondrial ribosomal protein L28
chr19_+_42886413 4.60 ENSDART00000151298
arpp21
cAMP-regulated phosphoprotein, 21
chr10_+_15608326 4.60 ENSDART00000188770
zfand5b
zinc finger, AN1-type domain 5b
chr2_-_27651674 4.59 ENSDART00000177402
tgs1
trimethylguanosine synthase 1
chr7_+_36467315 4.58 ENSDART00000138893
aktip
akt interacting protein
chr17_+_50261603 4.58 ENSDART00000154503
ENSDART00000154467
syncripl
synaptotagmin binding, cytoplasmic RNA interacting protein, like
chr7_+_54651109 4.58 ENSDART00000169987
oraov1
oral cancer overexpressed 1
chr23_-_21763598 4.57 ENSDART00000145408
vps13d
vacuolar protein sorting 13 homolog D (S. cerevisiae)
chr13_+_15816573 4.56 ENSDART00000137061
klc1a
kinesin light chain 1a
chr19_+_32979331 4.54 ENSDART00000078066
spire1a
spire-type actin nucleation factor 1a
chr17_+_45009868 4.54 ENSDART00000085009
coq6
coenzyme Q6 monooxygenase
chr17_-_868004 4.52 ENSDART00000112803
wdr20a
WD repeat domain 20a
chr16_+_25259313 4.50 ENSDART00000058938
fbxo32
F-box protein 32
chr1_-_6085750 4.49 ENSDART00000138891
si:ch1073-345a8.1
si:ch1073-345a8.1
chr7_-_71456117 4.49 ENSDART00000042492
sepsecs
Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase
chr10_+_3153973 4.47 ENSDART00000183223
hic2
hypermethylated in cancer 2
chr11_-_1550709 4.47 ENSDART00000110097
si:ch73-303b9.1
si:ch73-303b9.1
chr20_-_38827623 4.47 ENSDART00000153310
cad
carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
chr5_-_47975440 4.44 ENSDART00000145665
ENSDART00000007057
ccnh
cyclin H
chr15_+_17343319 4.42 ENSDART00000018461
vmp1
vacuole membrane protein 1
chr8_+_21280360 4.42 ENSDART00000144488
itpr3
inositol 1,4,5-trisphosphate receptor, type 3
chr1_-_9486214 4.39 ENSDART00000137821
micall2b
mical-like 2b
chr22_+_21549419 4.38 ENSDART00000139411
plpp2b
phospholipid phosphatase 2b
chr21_-_30994577 4.38 ENSDART00000065503
pgap2
post-GPI attachment to proteins 2
chr16_+_35918463 4.37 ENSDART00000160608
sh3d21
SH3 domain containing 21
chr1_-_9485939 4.36 ENSDART00000157814
micall2b
mical-like 2b
chr5_-_29195063 4.35 ENSDART00000109926
man1b1b
mannosidase, alpha, class 1B, member 1b
chr17_+_45010230 4.35 ENSDART00000192118
coq6
coenzyme Q6 monooxygenase
chr12_-_44759246 4.33 ENSDART00000162888
dock1
dedicator of cytokinesis 1
chr8_+_17143501 4.32 ENSDART00000061758
mier3b
mesoderm induction early response 1, family member 3 b
chr8_-_25034411 4.32 ENSDART00000135973
nfyal
nuclear transcription factor Y, alpha, like
chr8_+_21229718 4.31 ENSDART00000100222
cry1ba
cryptochrome circadian clock 1ba
chr7_+_10911396 4.31 ENSDART00000167273
ENSDART00000081323
ENSDART00000170655
abhd17c
abhydrolase domain containing 17C
chr4_-_13931293 4.30 ENSDART00000067172
zcrb1
zinc finger CCHC-type and RNA binding motif 1
chr21_+_21743599 4.30 ENSDART00000101700
pold3
polymerase (DNA-directed), delta 3, accessory subunit
chr9_+_8365398 4.28 ENSDART00000138713
ENSDART00000136847
si:dkey-90l23.2
si:dkey-90l23.2
chr23_-_18668836 4.27 ENSDART00000138792
ENSDART00000051182
arhgap4b
Rho GTPase activating protein 4b
chr8_-_44611357 4.24 ENSDART00000063396
bag4
BCL2 associated athanogene 4
chr25_+_753364 4.24 ENSDART00000183804
TWF1 (1 of many)
twinfilin actin binding protein 1
chr10_-_3394256 4.24 ENSDART00000158315
ENSDART00000111241
naa25
N(alpha)-acetyltransferase 25, NatB auxiliary subunit
chr3_+_17939828 4.22 ENSDART00000185047
cnp
2',3'-cyclic nucleotide 3' phosphodiesterase
chr11_+_25560072 4.21 ENSDART00000124131
ENSDART00000147179
mbd1b
methyl-CpG binding domain protein 1b
chr14_+_16083818 4.20 ENSDART00000168462
rnf103
ring finger protein 103
chr20_+_51730658 4.20 ENSDART00000010271
aida
axin interactor, dorsalization associated
chr23_+_9258531 4.20 ENSDART00000138745
acss2
acyl-CoA synthetase short chain family member 2
chr23_-_13840433 4.19 ENSDART00000104831
naa10
N(alpha)-acetyltransferase 10, NatA catalytic subunit
chr24_-_6024466 4.18 ENSDART00000040865
pdss1
prenyl (decaprenyl) diphosphate synthase, subunit 1
chr15_-_26931541 4.17 ENSDART00000027563
ccdc9
coiled-coil domain containing 9
chr21_-_19919918 4.15 ENSDART00000137307
ENSDART00000142523
ENSDART00000065670
ppp1r3b
protein phosphatase 1, regulatory subunit 3B
chr14_-_33858214 4.15 ENSDART00000112268
ocrl
oculocerebrorenal syndrome of Lowe
chr13_+_9559461 4.15 ENSDART00000047740
wdr32
WD repeat domain 32
chr5_+_25084385 4.14 ENSDART00000134526
ENSDART00000111863
paxx
PAXX, non-homologous end joining factor
chr2_+_49457449 4.13 ENSDART00000185470
sh3gl1a
SH3-domain GRB2-like 1a
chr4_-_858434 4.12 ENSDART00000006961
sobpb
sine oculis binding protein homolog (Drosophila) b
chr2_+_34112100 4.12 ENSDART00000056666
ENSDART00000146624
klhl20
kelch-like family member 20
chr8_+_47677208 4.11 ENSDART00000123254
dpp9
dipeptidyl-peptidase 9
chr19_+_41479990 4.11 ENSDART00000087187
ago2
argonaute RISC catalytic component 2
chr25_-_21782435 4.08 ENSDART00000089616
bmt2
base methyltransferase of 25S rRNA 2 homolog
chr24_+_25822999 4.07 ENSDART00000109809
sh3kbp1
SH3-domain kinase binding protein 1
chr16_+_33144306 4.06 ENSDART00000101953
rhbdl2
rhomboid, veinlet-like 2 (Drosophila)
chr17_+_34805897 4.05 ENSDART00000137090
ENSDART00000077626
id2a
inhibitor of DNA binding 2a
chr24_-_32522587 4.01 ENSDART00000048968
ENSDART00000143781
EIF1B
zgc:56676
chr15_-_34878388 4.01 ENSDART00000154094
mgat1a
mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase a
chr9_-_7287128 3.99 ENSDART00000176281
ENSDART00000065803
mitd1
MIT, microtubule interacting and transport, domain containing 1
chr7_-_25133783 3.99 ENSDART00000173781
ENSDART00000121943
ENSDART00000077219
badb
BCL2 associated agonist of cell death b
chr20_-_10487951 3.98 ENSDART00000064112
glrx5
glutaredoxin 5 homolog (S. cerevisiae)
chr25_+_8925934 3.98 ENSDART00000073914
accs
1-aminocyclopropane-1-carboxylate synthase homolog (Arabidopsis)(non-functional)
chr21_+_13245302 3.98 ENSDART00000189498
specc1lb
sperm antigen with calponin homology and coiled-coil domains 1-like b
chr3_-_30885250 3.96 ENSDART00000109104
kmt5c
lysine methyltransferase 5C
chr9_-_7287375 3.96 ENSDART00000128352
mitd1
MIT, microtubule interacting and transport, domain containing 1
chr15_-_16076399 3.96 ENSDART00000135658
ENSDART00000133755
ENSDART00000080413
srsf1a
serine/arginine-rich splicing factor 1a
chr15_+_11693624 3.96 ENSDART00000193630
ENSDART00000161930
strn4
striatin, calmodulin binding protein 4
chr8_+_3431671 3.95 ENSDART00000017850
ctu1
cytosolic thiouridylase subunit 1 homolog (S. pombe)
chr6_+_46406565 3.93 ENSDART00000168440
ENSDART00000131203
ENSDART00000138567
ENSDART00000132845
pbrm1l
polybromo 1, like
chr16_-_26232411 3.92 ENSDART00000139355
arhgef1b
Rho guanine nucleotide exchange factor (GEF) 1b
chr7_+_32693890 3.91 ENSDART00000121972
slc39a13
solute carrier family 39 (zinc transporter), member 13
chr22_-_17652112 3.91 ENSDART00000189205
hmha1b
histocompatibility (minor) HA-1 b
chr1_-_21881818 3.91 ENSDART00000047728
melk
maternal embryonic leucine zipper kinase
chr13_-_25484659 3.89 ENSDART00000135321
ENSDART00000022799
tial1
TIA1 cytotoxic granule-associated RNA binding protein-like 1
chr15_+_24756860 3.88 ENSDART00000156424
ENSDART00000078035
cpda
carboxypeptidase D, a
chr8_+_30742898 3.88 ENSDART00000018475
snrpd3
small nuclear ribonucleoprotein D3 polypeptide
chr17_+_12075805 3.87 ENSDART00000155329
cnsta
consortin, connexin sorting protein a
chr12_-_33789006 3.84 ENSDART00000034550
llgl2
lethal giant larvae homolog 2 (Drosophila)
chr21_+_17016337 3.84 ENSDART00000065755
gpn3
GPN-loop GTPase 3
chr13_-_12667220 3.83 ENSDART00000079594
fam241a
family with sequence similarity 241 member A
chr16_+_20294976 3.83 ENSDART00000059619
fkbp14
FK506 binding protein 14
chr25_+_33202294 3.83 ENSDART00000131098
TPM1 (1 of many)
zgc:171719
chr17_-_30635298 3.82 ENSDART00000155478
sh3yl1
SH3 and SYLF domain containing 1
chr12_-_9468618 3.80 ENSDART00000152737
ENSDART00000091519
pgap3
post-GPI attachment to proteins 3
chr10_+_10313024 3.80 ENSDART00000142895
ENSDART00000129952
urm1
ubiquitin related modifier 1
chr10_+_29771256 3.80 ENSDART00000193195
hyou1
hypoxia up-regulated 1
chr16_-_34285106 3.79 ENSDART00000044235
phactr4b
phosphatase and actin regulator 4b
chr13_+_25505580 3.79 ENSDART00000140634
inpp5f
inositol polyphosphate-5-phosphatase F
chr8_+_30743263 3.78 ENSDART00000181234
p2rx4b
purinergic receptor P2X, ligand-gated ion channel, 4b
chr9_-_21238616 3.77 ENSDART00000191840
ENSDART00000189127
cox17
COX17 cytochrome c oxidase copper chaperone
chr1_-_25486471 3.76 ENSDART00000134200
ENSDART00000141892
ENSDART00000102501
arfip1
ADP-ribosylation factor interacting protein 1 (arfaptin 1)
chr11_-_15874974 3.76 ENSDART00000166551
ENSDART00000129526
ENSDART00000165836
rap1ab
RAP1A, member of RAS oncogene family b
chr2_-_15040345 3.75 ENSDART00000109657
si:dkey-10f21.4
si:dkey-10f21.4
chr13_-_48431766 3.74 ENSDART00000159688
ENSDART00000171765
fbxo11a
F-box protein 11a
chr4_+_13931733 3.74 ENSDART00000141742
ENSDART00000067175
pphln1
periphilin 1
chr2_+_49805892 3.73 ENSDART00000056248
wdr48b
WD repeat domain 48b
chr2_+_38055529 3.73 ENSDART00000145642
si:rp71-1g18.1
si:rp71-1g18.1
chr2_-_29923403 3.71 ENSDART00000144672
paxip1
PAX interacting (with transcription-activation domain) protein 1
chr1_-_31105376 3.71 ENSDART00000132466
ppp1r9alb
protein phosphatase 1 regulatory subunit 9A-like B
chr19_+_2835240 3.69 ENSDART00000190838
CDCP1
CUB domain containing protein 1
chr1_+_25650917 3.69 ENSDART00000054235
plrg1
pleiotropic regulator 1

Network of associatons between targets according to the STRING database.

First level regulatory network of elf2a+elf2b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.0 11.8 GO:0071788 endoplasmic reticulum tubular network maintenance(GO:0071788)
2.6 7.8 GO:0071470 cellular response to osmotic stress(GO:0071470)
2.3 6.9 GO:0021531 spinal cord radial glial cell differentiation(GO:0021531)
2.3 6.8 GO:2000378 negative regulation of reactive oxygen species metabolic process(GO:2000378)
2.2 6.5 GO:0001562 response to protozoan(GO:0001562) defense response to protozoan(GO:0042832)
2.1 12.4 GO:0032447 protein urmylation(GO:0032447)
1.9 5.6 GO:0000390 spliceosomal complex disassembly(GO:0000390)
1.8 5.5 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
1.7 8.5 GO:0097355 protein localization to heterochromatin(GO:0097355)
1.7 10.1 GO:0070734 histone H3-K27 methylation(GO:0070734)
1.6 6.3 GO:0036462 TRAIL-activated apoptotic signaling pathway(GO:0036462)
1.5 6.1 GO:0048211 Golgi vesicle docking(GO:0048211)
1.5 4.5 GO:0006451 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
1.5 4.5 GO:0021563 glossopharyngeal nerve development(GO:0021563)
1.5 7.4 GO:0008594 photoreceptor cell morphogenesis(GO:0008594) negative regulation of epithelial to mesenchymal transition(GO:0010719)
1.5 8.7 GO:0060251 regulation of glial cell proliferation(GO:0060251)
1.4 4.3 GO:0070914 UV-damage excision repair(GO:0070914)
1.4 8.5 GO:0060832 oocyte animal/vegetal axis specification(GO:0060832)
1.4 4.2 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
1.4 5.5 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
1.3 4.0 GO:0097095 frontonasal suture morphogenesis(GO:0097095)
1.3 4.0 GO:0034770 histone H4-K20 methylation(GO:0034770) histone H4-K20 trimethylation(GO:0034773)
1.3 2.6 GO:0060019 radial glial cell differentiation(GO:0060019)
1.3 3.9 GO:0042998 positive regulation of Golgi to plasma membrane protein transport(GO:0042998) positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
1.2 3.7 GO:1903003 positive regulation of protein deubiquitination(GO:1903003)
1.2 9.7 GO:0070933 histone H4 deacetylation(GO:0070933)
1.2 3.5 GO:0043903 regulation of symbiosis, encompassing mutualism through parasitism(GO:0043903)
1.1 3.4 GO:0072387 FAD biosynthetic process(GO:0006747) FAD metabolic process(GO:0046443) flavin adenine dinucleotide metabolic process(GO:0072387) flavin adenine dinucleotide biosynthetic process(GO:0072388)
1.1 7.8 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
1.0 3.1 GO:0005997 xylulose metabolic process(GO:0005997)
1.0 4.2 GO:0071867 response to monoamine(GO:0071867) response to catecholamine(GO:0071869) response to epinephrine(GO:0071871)
1.0 2.1 GO:0035513 oxidative RNA demethylation(GO:0035513)
1.0 5.1 GO:0098795 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
1.0 3.0 GO:1905072 cardiac jelly development(GO:1905072)
1.0 3.8 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
0.9 8.5 GO:0006465 signal peptide processing(GO:0006465)
0.9 6.6 GO:0040014 regulation of multicellular organism growth(GO:0040014)
0.9 4.7 GO:0030328 prenylated protein catabolic process(GO:0030327) prenylcysteine catabolic process(GO:0030328) prenylcysteine metabolic process(GO:0030329)
0.9 6.5 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.9 3.7 GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518)
0.9 3.7 GO:0090140 regulation of mitochondrial fission(GO:0090140)
0.9 6.4 GO:0045053 protein retention in Golgi apparatus(GO:0045053)
0.9 3.7 GO:0060283 negative regulation of oocyte development(GO:0060283)
0.9 2.7 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.9 7.1 GO:0019405 alditol catabolic process(GO:0019405)
0.9 4.4 GO:0051792 medium-chain fatty acid biosynthetic process(GO:0051792)
0.9 17.4 GO:0007032 endosome organization(GO:0007032)
0.9 3.4 GO:0051645 Golgi localization(GO:0051645)
0.9 5.1 GO:0072422 signal transduction involved in DNA integrity checkpoint(GO:0072401) signal transduction involved in DNA damage checkpoint(GO:0072422) signal transduction involved in G2 DNA damage checkpoint(GO:0072425)
0.8 17.8 GO:0006825 copper ion transport(GO:0006825)
0.8 0.8 GO:1903430 negative regulation of cell maturation(GO:1903430)
0.8 5.9 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.8 4.2 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.8 2.5 GO:0060148 negative regulation of hippo signaling(GO:0035331) positive regulation of posttranscriptional gene silencing(GO:0060148) positive regulation of gene silencing by miRNA(GO:2000637)
0.8 3.3 GO:0006046 N-acetylglucosamine catabolic process(GO:0006046)
0.8 7.5 GO:0046716 muscle cell cellular homeostasis(GO:0046716)
0.8 2.5 GO:0070537 histone H2A K63-linked deubiquitination(GO:0070537)
0.8 2.5 GO:0009193 ribonucleoside diphosphate catabolic process(GO:0009191) pyrimidine ribonucleoside diphosphate metabolic process(GO:0009193) UDP metabolic process(GO:0046048)
0.8 2.4 GO:0090435 protein targeting to nuclear inner membrane(GO:0036228) protein localization to nuclear envelope(GO:0090435)
0.8 8.8 GO:0034312 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.8 5.6 GO:0046426 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.8 3.1 GO:0042754 negative regulation of circadian rhythm(GO:0042754)
0.8 5.4 GO:0036010 protein localization to endosome(GO:0036010)
0.8 3.1 GO:0032655 interleukin-12 production(GO:0032615) regulation of interleukin-12 production(GO:0032655)
0.8 3.8 GO:1902804 negative regulation of neurotransmitter secretion(GO:0046929) response to cAMP(GO:0051591) cellular response to cAMP(GO:0071320) negative regulation of synaptic vesicle transport(GO:1902804) negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.7 8.9 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.7 6.6 GO:0051189 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.7 4.4 GO:0003188 heart valve formation(GO:0003188) atrioventricular valve formation(GO:0003190)
0.7 2.9 GO:0032530 regulation of microvillus organization(GO:0032530) regulation of microvillus assembly(GO:0032534)
0.7 5.7 GO:0044528 regulation of mitochondrial mRNA stability(GO:0044528)
0.7 4.2 GO:0006083 acetate metabolic process(GO:0006083) acetyl-CoA biosynthetic process from acetate(GO:0019427)
0.7 2.1 GO:0034421 post-translational protein acetylation(GO:0034421)
0.7 3.5 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.7 13.8 GO:0032885 regulation of polysaccharide biosynthetic process(GO:0032885)
0.7 4.1 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.7 4.7 GO:0060036 notochord cell vacuolation(GO:0060036)
0.7 1.3 GO:0009438 methylglyoxal metabolic process(GO:0009438)
0.7 2.0 GO:0035046 pronuclear migration(GO:0035046)
0.7 8.0 GO:0045842 positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.7 2.0 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.7 3.3 GO:0018197 peptidyl-aspartic acid modification(GO:0018197) peptidyl-aspartic acid hydroxylation(GO:0042264)
0.7 2.0 GO:0033512 L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512)
0.7 3.3 GO:0071422 thiosulfate transport(GO:0015709) oxaloacetate transport(GO:0015729) malate transport(GO:0015743) succinate transport(GO:0015744) succinate transmembrane transport(GO:0071422) malate transmembrane transport(GO:0071423)
0.7 2.0 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)
0.7 13.1 GO:1901663 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.6 1.9 GO:0010259 multicellular organism aging(GO:0010259)
0.6 2.6 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.6 5.0 GO:0051013 microtubule severing(GO:0051013)
0.6 3.7 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.6 3.7 GO:0044209 AMP salvage(GO:0044209)
0.6 3.7 GO:0016559 peroxisome fission(GO:0016559)
0.6 2.4 GO:0050435 beta-amyloid metabolic process(GO:0050435)
0.6 8.9 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.6 2.3 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.6 6.9 GO:1904356 regulation of telomere maintenance via telomere lengthening(GO:1904356)
0.6 4.6 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.6 2.3 GO:1903292 protein localization to Golgi membrane(GO:1903292)
0.6 0.6 GO:0097501 stress response to metal ion(GO:0097501)
0.6 4.5 GO:0033206 meiotic cytokinesis(GO:0033206) polar body extrusion after meiotic divisions(GO:0040038)
0.6 1.7 GO:1903069 regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903069)
0.6 2.8 GO:0019388 galactose catabolic process(GO:0019388) galactose catabolic process via UDP-galactose(GO:0033499)
0.5 14.3 GO:1903845 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) negative regulation of cellular response to transforming growth factor beta stimulus(GO:1903845)
0.5 3.2 GO:0018214 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.5 1.5 GO:0035511 oxidative DNA demethylation(GO:0035511)
0.5 10.6 GO:0006301 postreplication repair(GO:0006301)
0.5 2.0 GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787) regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000058)
0.5 6.5 GO:0061055 myotome development(GO:0061055)
0.5 1.5 GO:0001579 medium-chain fatty acid transport(GO:0001579)
0.5 3.0 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.5 2.9 GO:0090314 regulation of protein targeting to membrane(GO:0090313) positive regulation of protein targeting to membrane(GO:0090314)
0.5 2.4 GO:1903405 nuclear body organization(GO:0030575) Cajal body organization(GO:0030576) protein localization to nuclear body(GO:1903405) protein localization to Cajal body(GO:1904867) protein localization to nucleoplasm(GO:1990173)
0.5 13.6 GO:0006303 double-strand break repair via nonhomologous end joining(GO:0006303)
0.5 11.6 GO:0007520 myoblast fusion(GO:0007520)
0.5 1.9 GO:0019254 carnitine metabolic process, CoA-linked(GO:0019254)
0.5 3.2 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.5 4.1 GO:0007220 Notch receptor processing(GO:0007220)
0.5 5.5 GO:0021702 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.5 4.1 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.5 6.4 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.4 4.0 GO:0031573 intra-S DNA damage checkpoint(GO:0031573)
0.4 2.2 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.4 1.8 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.4 4.0 GO:0071479 cellular response to ionizing radiation(GO:0071479)
0.4 2.7 GO:0000455 enzyme-directed rRNA pseudouridine synthesis(GO:0000455)
0.4 3.5 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.4 6.9 GO:2000223 regulation of BMP signaling pathway involved in heart jogging(GO:2000223)
0.4 2.1 GO:0040016 embryonic cleavage(GO:0040016)
0.4 0.9 GO:0006297 nucleotide-excision repair, DNA gap filling(GO:0006297)
0.4 2.5 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.4 6.8 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.4 1.3 GO:0060912 cardiac cell fate specification(GO:0060912)
0.4 2.1 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.4 2.9 GO:0006621 protein retention in ER lumen(GO:0006621)
0.4 2.8 GO:0070073 clustering of voltage-gated calcium channels(GO:0070073)
0.4 8.9 GO:0006491 N-glycan processing(GO:0006491)
0.4 1.2 GO:0019284 L-methionine biosynthetic process from S-adenosylmethionine(GO:0019284)
0.4 2.4 GO:0003422 growth plate cartilage morphogenesis(GO:0003422) chondrocyte intercalation involved in growth plate cartilage morphogenesis(GO:0003428)
0.4 8.4 GO:0031163 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.4 2.0 GO:0000393 spliceosomal conformational changes to generate catalytic conformation(GO:0000393)
0.4 1.2 GO:1901187 regulation of ephrin receptor signaling pathway(GO:1901187)
0.4 0.8 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848) telomere maintenance in response to DNA damage(GO:0043247) negative regulation of DNA recombination at telomere(GO:0048239) regulation of DNA recombination at telomere(GO:0072695)
0.4 7.4 GO:0034661 ncRNA catabolic process(GO:0034661)
0.4 2.3 GO:0018160 peptidyl-pyrromethane cofactor linkage(GO:0018160)
0.4 1.9 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.4 2.3 GO:0001887 selenium compound metabolic process(GO:0001887)
0.4 1.1 GO:2000425 regulation of apoptotic cell clearance(GO:2000425)
0.4 3.0 GO:1904086 regulation of epiboly involved in gastrulation with mouth forming second(GO:1904086)
0.4 5.9 GO:0072554 endothelial tube morphogenesis(GO:0061154) blood vessel lumenization(GO:0072554)
0.4 10.6 GO:0035305 negative regulation of dephosphorylation(GO:0035305) negative regulation of protein dephosphorylation(GO:0035308)
0.4 2.9 GO:0048730 epidermis morphogenesis(GO:0048730)
0.4 5.3 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.4 1.8 GO:0043931 ossification involved in bone maturation(GO:0043931) bone maturation(GO:0070977)
0.4 2.5 GO:0031048 chromatin silencing by small RNA(GO:0031048)
0.3 2.1 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.3 1.0 GO:1903726 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553) negative regulation of lipid kinase activity(GO:0090219) negative regulation of phospholipid metabolic process(GO:1903726)
0.3 5.1 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.3 1.0 GO:0031338 regulation of vesicle fusion(GO:0031338) positive regulation of vesicle fusion(GO:0031340)
0.3 2.0 GO:0031112 positive regulation of microtubule polymerization or depolymerization(GO:0031112) positive regulation of microtubule polymerization(GO:0031116)
0.3 3.3 GO:0002042 cell migration involved in sprouting angiogenesis(GO:0002042)
0.3 8.6 GO:0090148 membrane fission(GO:0090148)
0.3 4.3 GO:0002084 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.3 3.2 GO:2000047 regulation of cell-cell adhesion mediated by cadherin(GO:2000047)
0.3 1.9 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398) histone mRNA metabolic process(GO:0008334)
0.3 0.6 GO:0071027 nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028) nuclear retention of pre-mRNA at the site of transcription(GO:0071033)
0.3 2.9 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.3 2.2 GO:0045050 protein insertion into ER membrane by stop-transfer membrane-anchor sequence(GO:0045050)
0.3 6.4 GO:0006896 Golgi to vacuole transport(GO:0006896)
0.3 12.1 GO:0046466 sphingolipid catabolic process(GO:0030149) membrane lipid catabolic process(GO:0046466)
0.3 3.8 GO:0046683 response to purine-containing compound(GO:0014074) response to organophosphorus(GO:0046683)
0.3 1.5 GO:0009240 isopentenyl diphosphate biosynthetic process(GO:0009240) isopentenyl diphosphate metabolic process(GO:0046490)
0.3 2.2 GO:0032475 otolith formation(GO:0032475)
0.3 0.6 GO:0045922 negative regulation of fatty acid metabolic process(GO:0045922)
0.3 1.2 GO:0070131 regulation of mitochondrial translation(GO:0070129) positive regulation of mitochondrial translation(GO:0070131)
0.3 1.8 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.3 0.9 GO:0046632 alpha-beta T cell differentiation(GO:0046632)
0.3 2.7 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.3 0.9 GO:0097237 cellular response to antibiotic(GO:0071236) cellular response to toxic substance(GO:0097237)
0.3 4.5 GO:0030330 DNA damage response, signal transduction by p53 class mediator(GO:0030330)
0.3 4.1 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.3 3.5 GO:0051382 kinetochore assembly(GO:0051382)
0.3 1.4 GO:0003173 ventriculo bulbo valve development(GO:0003173)
0.3 4.0 GO:0007096 regulation of exit from mitosis(GO:0007096)
0.3 9.4 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.3 2.3 GO:0003365 establishment of cell polarity involved in ameboidal cell migration(GO:0003365)
0.3 2.8 GO:0031268 pseudopodium organization(GO:0031268) pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.3 0.6 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.3 1.4 GO:0046462 phosphatidylserine catabolic process(GO:0006660) monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.3 1.1 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.3 1.1 GO:0033313 meiotic cell cycle checkpoint(GO:0033313)
0.3 1.9 GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.3 2.4 GO:0048207 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.3 5.4 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.3 2.4 GO:0030497 fatty acid elongation(GO:0030497)
0.3 2.3 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.3 2.9 GO:0038203 TORC2 signaling(GO:0038203)
0.3 0.8 GO:0009211 pyrimidine deoxyribonucleoside triphosphate metabolic process(GO:0009211)
0.3 0.8 GO:0045724 positive regulation of cilium assembly(GO:0045724)
0.3 1.0 GO:0006499 N-terminal protein myristoylation(GO:0006499) N-terminal peptidyl-glycine N-myristoylation(GO:0018008) protein myristoylation(GO:0018377)
0.3 4.4 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.3 4.6 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.3 1.3 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.2 1.7 GO:0048742 regulation of myotube differentiation(GO:0010830) regulation of skeletal muscle fiber development(GO:0048742)
0.2 1.5 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.2 1.2 GO:2001106 regulation of guanyl-nucleotide exchange factor activity(GO:1905097) regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.2 25.2 GO:0006401 RNA catabolic process(GO:0006401)
0.2 0.7 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.2 1.4 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.2 3.5 GO:0045116 protein neddylation(GO:0045116)
0.2 2.5 GO:0007584 response to nutrient(GO:0007584)
0.2 3.2 GO:0016926 protein desumoylation(GO:0016926)
0.2 0.7 GO:0006901 vesicle coating(GO:0006901) COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.2 2.0 GO:0071376 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.2 4.0 GO:0046660 female sex differentiation(GO:0046660)
0.2 4.9 GO:0033138 positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.2 4.2 GO:0044872 lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
0.2 1.1 GO:1902262 apoptotic process involved in patterning of blood vessels(GO:1902262)
0.2 3.0 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.2 6.6 GO:0051014 actin filament severing(GO:0051014)
0.2 0.6 GO:0072526 pyridine nucleotide catabolic process(GO:0019364) NAD catabolic process(GO:0019677) pyridine-containing compound catabolic process(GO:0072526)
0.2 1.5 GO:0045048 protein insertion into ER membrane(GO:0045048)
0.2 1.0 GO:0060876 semicircular canal formation(GO:0060876)
0.2 1.8 GO:0097345 mitochondrial outer membrane permeabilization(GO:0097345)
0.2 2.4 GO:0009791 post-embryonic development(GO:0009791)
0.2 5.2 GO:0048264 determination of ventral identity(GO:0048264)
0.2 7.0 GO:0014866 skeletal myofibril assembly(GO:0014866)
0.2 1.8 GO:0042135 neurotransmitter catabolic process(GO:0042135)
0.2 1.6 GO:0006478 protein sulfation(GO:0006477) peptidyl-tyrosine sulfation(GO:0006478)
0.2 2.8 GO:0061300 cerebellum vasculature development(GO:0061300)
0.2 1.8 GO:0006658 phosphatidylserine metabolic process(GO:0006658)
0.2 4.7 GO:0038061 NIK/NF-kappaB signaling(GO:0038061)
0.2 3.7 GO:0008354 germ cell migration(GO:0008354)
0.2 1.9 GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625)
0.2 0.6 GO:0051095 regulation of helicase activity(GO:0051095) positive regulation of helicase activity(GO:0051096)
0.2 2.5 GO:0043687 post-translational protein modification(GO:0043687)
0.2 1.7 GO:1902038 positive regulation of hematopoietic stem cell differentiation(GO:1902038)
0.2 0.8 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.2 14.5 GO:0006400 tRNA modification(GO:0006400)
0.2 1.3 GO:0048660 regulation of smooth muscle cell proliferation(GO:0048660) negative regulation of smooth muscle cell proliferation(GO:0048662)
0.2 3.8 GO:0034315 regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315)
0.2 1.9 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.2 1.3 GO:0097010 eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.2 6.3 GO:0031629 synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.2 7.2 GO:0035336 long-chain fatty-acyl-CoA metabolic process(GO:0035336)
0.2 0.2 GO:0042726 flavin-containing compound metabolic process(GO:0042726) flavin-containing compound biosynthetic process(GO:0042727)
0.2 1.5 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.2 3.6 GO:0071456 cellular response to hypoxia(GO:0071456)
0.2 2.9 GO:0060029 convergent extension involved in organogenesis(GO:0060029)
0.2 1.6 GO:0035188 hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.2 2.7 GO:0048844 artery morphogenesis(GO:0048844)
0.2 51.2 GO:0000398 RNA splicing, via transesterification reactions(GO:0000375) RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)
0.2 13.0 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.2 10.4 GO:0018210 peptidyl-threonine modification(GO:0018210)
0.2 1.0 GO:0035313 wound healing, spreading of epidermal cells(GO:0035313) negative regulation of ruffle assembly(GO:1900028)
0.2 4.0 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.2 0.5 GO:0070417 cellular response to cold(GO:0070417)
0.2 2.0 GO:0016188 synaptic vesicle maturation(GO:0016188)
0.2 1.5 GO:0009264 deoxyribonucleotide catabolic process(GO:0009264) deoxyribose phosphate catabolic process(GO:0046386)
0.2 0.9 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.2 3.2 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.2 4.9 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.2 4.5 GO:0006893 Golgi to plasma membrane transport(GO:0006893)
0.2 1.0 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.2 0.7 GO:1901492 positive regulation of lymphangiogenesis(GO:1901492)
0.2 0.6 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.2 2.3 GO:0002138 retinoic acid biosynthetic process(GO:0002138)
0.2 1.5 GO:0061098 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741) positive regulation of protein tyrosine kinase activity(GO:0061098) positive regulation of receptor activity(GO:2000273)
0.2 6.5 GO:0036269 swimming behavior(GO:0036269)
0.2 0.8 GO:0070587 regulation of cell-cell adhesion involved in gastrulation(GO:0070587)
0.2 2.0 GO:0048702 embryonic neurocranium morphogenesis(GO:0048702)
0.2 2.3 GO:0015781 pyrimidine nucleotide-sugar transport(GO:0015781) pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.2 6.8 GO:0030901 midbrain development(GO:0030901)
0.2 3.2 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.2 6.2 GO:0032456 endocytic recycling(GO:0032456)
0.1 2.2 GO:0016486 peptide hormone processing(GO:0016486)
0.1 0.3 GO:0035264 multicellular organism growth(GO:0035264)
0.1 0.9 GO:0016048 detection of temperature stimulus(GO:0016048) sensory perception of temperature stimulus(GO:0050951)
0.1 6.0 GO:0060389 pathway-restricted SMAD protein phosphorylation(GO:0060389)
0.1 0.5 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.1 2.6 GO:0061351 neural precursor cell proliferation(GO:0061351)
0.1 3.5 GO:0045454 cell redox homeostasis(GO:0045454)
0.1 4.4 GO:0051209 release of sequestered calcium ion into cytosol(GO:0051209)
0.1 6.7 GO:0046854 lipid phosphorylation(GO:0046834) phosphatidylinositol phosphorylation(GO:0046854)
0.1 1.8 GO:0032418 lysosome localization(GO:0032418)
0.1 0.5 GO:0032486 Rap protein signal transduction(GO:0032486)
0.1 3.0 GO:1903039 positive regulation of cell-cell adhesion(GO:0022409) positive regulation of homotypic cell-cell adhesion(GO:0034112) positive regulation of T cell activation(GO:0050870) positive regulation of leukocyte cell-cell adhesion(GO:1903039)
0.1 1.4 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.1 4.4 GO:0007179 transforming growth factor beta receptor signaling pathway(GO:0007179) response to transforming growth factor beta(GO:0071559) cellular response to transforming growth factor beta stimulus(GO:0071560)
0.1 0.8 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.1 0.7 GO:0034724 DNA replication-independent nucleosome assembly(GO:0006336) DNA replication-independent nucleosome organization(GO:0034724)
0.1 5.6 GO:1904018 positive regulation of angiogenesis(GO:0045766) positive regulation of vasculature development(GO:1904018)
0.1 2.9 GO:0050821 protein stabilization(GO:0050821)
0.1 0.6 GO:0090245 axis elongation involved in somitogenesis(GO:0090245)
0.1 1.1 GO:0006108 malate metabolic process(GO:0006108)
0.1 1.6 GO:0038202 TORC1 signaling(GO:0038202)
0.1 1.0 GO:1904825 protein localization to microtubule(GO:0035372) protein localization to microtubule plus-end(GO:1904825)
0.1 3.8 GO:0060028 convergent extension involved in axis elongation(GO:0060028)
0.1 1.9 GO:0015693 magnesium ion transport(GO:0015693)
0.1 4.7 GO:0030336 negative regulation of cell migration(GO:0030336)
0.1 2.6 GO:0009395 phospholipid catabolic process(GO:0009395)
0.1 0.3 GO:0080182 histone H3-K4 trimethylation(GO:0080182) histone H3-K36 dimethylation(GO:0097676)
0.1 0.9 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.1 4.6 GO:1990542 mitochondrial transmembrane transport(GO:1990542)
0.1 0.7 GO:0010575 vascular endothelial growth factor production(GO:0010573) regulation of vascular endothelial growth factor production(GO:0010574) positive regulation of vascular endothelial growth factor production(GO:0010575) esophagus smooth muscle contraction(GO:0014846) glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.1 0.4 GO:1903232 melanosome assembly(GO:1903232)
0.1 0.5 GO:0030520 intracellular estrogen receptor signaling pathway(GO:0030520)
0.1 0.2 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509) amino acid salvage(GO:0043102) L-methionine biosynthetic process(GO:0071265) L-methionine salvage(GO:0071267)
0.1 1.7 GO:0000460 maturation of 5.8S rRNA(GO:0000460)
0.1 1.7 GO:0006513 protein monoubiquitination(GO:0006513)
0.1 4.5 GO:0031102 neuron projection regeneration(GO:0031102)
0.1 2.2 GO:0048263 determination of dorsal identity(GO:0048263)
0.1 1.5 GO:0051639 actin filament network formation(GO:0051639)
0.1 5.9 GO:0015914 phospholipid transport(GO:0015914)
0.1 6.0 GO:0007030 Golgi organization(GO:0007030)
0.1 0.2 GO:0071545 phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855) inositol phosphate catabolic process(GO:0071545)
0.1 2.7 GO:0019432 triglyceride biosynthetic process(GO:0019432)
0.1 0.6 GO:0031998 regulation of fatty acid beta-oxidation(GO:0031998)
0.1 0.3 GO:0070072 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.1 2.3 GO:0006688 glycosphingolipid biosynthetic process(GO:0006688)
0.1 1.2 GO:0032474 otolith morphogenesis(GO:0032474)
0.1 0.2 GO:0000098 sulfur amino acid catabolic process(GO:0000098)
0.1 2.6 GO:0000281 mitotic cytokinesis(GO:0000281)
0.1 2.6 GO:0072348 sulfur compound transport(GO:0072348)
0.1 1.4 GO:0006998 nuclear envelope organization(GO:0006998)
0.1 2.4 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.1 9.9 GO:0090630 activation of GTPase activity(GO:0090630)
0.1 9.4 GO:0008544 epidermis development(GO:0008544)
0.1 1.9 GO:0006626 protein targeting to mitochondrion(GO:0006626)
0.1 0.6 GO:0035987 endodermal cell differentiation(GO:0035987)
0.1 0.9 GO:0070189 kynurenine metabolic process(GO:0070189)
0.1 0.5 GO:0016233 telomere capping(GO:0016233)
0.1 2.9 GO:0061640 cytoskeleton-dependent cytokinesis(GO:0061640)
0.1 0.9 GO:0010717 regulation of epithelial to mesenchymal transition(GO:0010717)
0.1 0.2 GO:0051958 folic acid transport(GO:0015884) drug transport(GO:0015893) methotrexate transport(GO:0051958) reduced folate transmembrane transport(GO:0098838)
0.1 1.7 GO:0048840 otolith development(GO:0048840)
0.1 0.5 GO:0034394 protein localization to cell surface(GO:0034394)
0.1 1.0 GO:0032264 IMP salvage(GO:0032264)
0.1 3.7 GO:0055088 lipid homeostasis(GO:0055088)
0.1 1.2 GO:0098962 regulation of postsynaptic neurotransmitter receptor activity(GO:0098962)
0.1 3.1 GO:0034968 histone lysine methylation(GO:0034968)
0.1 1.5 GO:0043249 erythrocyte maturation(GO:0043249)
0.1 1.2 GO:1902622 regulation of neutrophil migration(GO:1902622)
0.1 4.5 GO:0008360 regulation of cell shape(GO:0008360)
0.1 0.9 GO:1903311 regulation of mRNA metabolic process(GO:1903311)
0.1 3.9 GO:0043406 positive regulation of MAP kinase activity(GO:0043406)
0.1 2.8 GO:0043484 regulation of RNA splicing(GO:0043484)
0.1 0.5 GO:0046822 regulation of nucleocytoplasmic transport(GO:0046822)
0.1 0.2 GO:0050927 regulation of positive chemotaxis(GO:0050926) positive regulation of positive chemotaxis(GO:0050927) induction of positive chemotaxis(GO:0050930)
0.1 5.9 GO:0009953 dorsal/ventral pattern formation(GO:0009953)
0.1 0.3 GO:0042249 establishment of planar polarity of embryonic epithelium(GO:0042249) establishment of planar polarity involved in neural tube closure(GO:0090177) regulation of establishment of planar polarity involved in neural tube closure(GO:0090178) planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.1 1.2 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.1 5.2 GO:1903706 regulation of hemopoiesis(GO:1903706)
0.1 1.2 GO:0042476 odontogenesis(GO:0042476)
0.1 1.6 GO:0050708 regulation of protein secretion(GO:0050708)
0.1 0.2 GO:0043489 RNA stabilization(GO:0043489)
0.1 1.2 GO:0009306 protein secretion(GO:0009306)
0.1 0.9 GO:0018126 protein hydroxylation(GO:0018126)
0.1 0.2 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.1 0.4 GO:0046037 GMP biosynthetic process(GO:0006177) GMP metabolic process(GO:0046037)
0.1 0.2 GO:0007638 mechanosensory behavior(GO:0007638)
0.0 2.2 GO:0035383 acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.0 2.7 GO:0006497 protein lipidation(GO:0006497)
0.0 10.8 GO:0006470 protein dephosphorylation(GO:0006470)
0.0 1.4 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 3.9 GO:0006909 phagocytosis(GO:0006909)
0.0 0.4 GO:0034122 negative regulation of toll-like receptor signaling pathway(GO:0034122)
0.0 0.1 GO:0006296 nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296)
0.0 1.3 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 0.4 GO:1901678 heme transport(GO:0015886) iron coordination entity transport(GO:1901678)
0.0 1.7 GO:0006354 DNA-templated transcription, elongation(GO:0006354)
0.0 1.8 GO:0007019 microtubule depolymerization(GO:0007019)
0.0 0.2 GO:0055005 ventricular cardiac myofibril assembly(GO:0055005)
0.0 0.0 GO:0002090 regulation of receptor internalization(GO:0002090) negative regulation of receptor-mediated endocytosis(GO:0048261)
0.0 1.4 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.0 0.8 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.0 1.5 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.0 1.1 GO:0016925 protein sumoylation(GO:0016925)
0.0 1.2 GO:0003351 epithelial cilium movement(GO:0003351)
0.0 4.0 GO:0030155 regulation of cell adhesion(GO:0030155)
0.0 0.1 GO:2000781 positive regulation of double-strand break repair(GO:2000781)
0.0 0.4 GO:0080171 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.0 3.7 GO:0043547 positive regulation of GTPase activity(GO:0043547)
0.0 4.8 GO:0018105 peptidyl-serine phosphorylation(GO:0018105)
0.0 0.3 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0 0.4 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 0.8 GO:0003094 glomerular filtration(GO:0003094)
0.0 0.3 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0 0.8 GO:0030098 lymphocyte differentiation(GO:0030098)
0.0 1.7 GO:0006606 protein import into nucleus(GO:0006606) protein targeting to nucleus(GO:0044744) single-organism nuclear import(GO:1902593)
0.0 0.2 GO:0032889 regulation of vacuole fusion, non-autophagic(GO:0032889)
0.0 1.0 GO:0032869 cellular response to insulin stimulus(GO:0032869)
0.0 1.1 GO:0000082 G1/S transition of mitotic cell cycle(GO:0000082)
0.0 0.2 GO:0002154 thyroid hormone mediated signaling pathway(GO:0002154)
0.0 2.8 GO:0006631 fatty acid metabolic process(GO:0006631)
0.0 0.4 GO:0045841 mitotic spindle assembly checkpoint(GO:0007094) spindle checkpoint(GO:0031577) negative regulation of mitotic metaphase/anaphase transition(GO:0045841) spindle assembly checkpoint(GO:0071173) mitotic spindle checkpoint(GO:0071174)
0.0 1.3 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.0 0.9 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.5 GO:0021522 spinal cord motor neuron differentiation(GO:0021522)
0.0 0.6 GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage(GO:0008630)
0.0 0.4 GO:0033627 cell adhesion mediated by integrin(GO:0033627)
0.0 0.9 GO:0035825 reciprocal DNA recombination(GO:0035825)
0.0 0.6 GO:0032508 DNA geometric change(GO:0032392) DNA duplex unwinding(GO:0032508)
0.0 0.3 GO:0035999 tetrahydrofolate interconversion(GO:0035999)
0.0 0.4 GO:0043534 blood vessel endothelial cell migration(GO:0043534)
0.0 0.9 GO:0007249 I-kappaB kinase/NF-kappaB signaling(GO:0007249)
0.0 2.0 GO:0019221 cytokine-mediated signaling pathway(GO:0019221)
0.0 0.3 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.0 1.0 GO:0099518 vesicle cytoskeletal trafficking(GO:0099518)
0.0 0.1 GO:0010269 response to selenium ion(GO:0010269)
0.0 0.3 GO:0007492 endoderm development(GO:0007492)
0.0 1.4 GO:0048511 rhythmic process(GO:0048511)
0.0 0.5 GO:0006937 regulation of muscle contraction(GO:0006937)
0.0 0.5 GO:0006487 protein N-linked glycosylation(GO:0006487)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.8 8.3 GO:0098826 endoplasmic reticulum tubular network membrane(GO:0098826)
1.7 5.0 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
1.6 6.4 GO:0005787 signal peptidase complex(GO:0005787)
1.6 4.7 GO:0031251 PAN complex(GO:0031251)
1.4 5.5 GO:0043291 RAVE complex(GO:0043291)
1.3 3.8 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
1.3 7.5 GO:0070695 FHF complex(GO:0070695)
1.2 7.4 GO:0019008 molybdopterin synthase complex(GO:0019008)
1.1 4.4 GO:0097524 sperm plasma membrane(GO:0097524)
1.1 3.3 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
1.1 8.5 GO:0032019 mitochondrial cloud(GO:0032019)
1.0 8.9 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
1.0 4.9 GO:0031515 tRNA (m1A) methyltransferase complex(GO:0031515)
0.9 5.6 GO:0000835 ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836)
0.9 10.2 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.9 2.8 GO:0042709 succinate-CoA ligase complex(GO:0042709)
0.9 15.4 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.9 5.2 GO:0000938 GARP complex(GO:0000938)
0.9 4.3 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.8 8.4 GO:0031414 N-terminal protein acetyltransferase complex(GO:0031414)
0.8 6.7 GO:0031332 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.8 8.9 GO:0005675 holo TFIIH complex(GO:0005675)
0.7 2.1 GO:0098536 deuterosome(GO:0098536)
0.7 5.5 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.7 2.6 GO:0045293 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.7 5.2 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.6 3.1 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.6 2.4 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.6 7.0 GO:0097431 mitotic spindle pole(GO:0097431)
0.6 1.7 GO:0032593 insulin-responsive compartment(GO:0032593)
0.5 4.3 GO:0005682 U5 snRNP(GO:0005682)
0.5 2.1 GO:0071556 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.5 4.1 GO:0070419 nonhomologous end joining complex(GO:0070419)
0.5 4.1 GO:0070765 gamma-secretase complex(GO:0070765)
0.5 2.0 GO:0061673 mitotic spindle astral microtubule(GO:0061673)
0.5 2.0 GO:0072588 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.5 7.4 GO:0070187 telosome(GO:0070187)
0.5 3.9 GO:0016586 RSC complex(GO:0016586)
0.5 4.4 GO:0000974 Prp19 complex(GO:0000974)
0.5 3.2 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.5 1.8 GO:0071005 U2-type precatalytic spliceosome(GO:0071005)
0.5 4.6 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.4 4.0 GO:0089701 U2AF(GO:0089701)
0.4 2.5 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.4 5.3 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.4 4.0 GO:0031211 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.4 8.0 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.4 2.8 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.4 2.7 GO:0035517 PR-DUB complex(GO:0035517)
0.4 8.2 GO:0030127 COPII vesicle coat(GO:0030127)
0.4 9.3 GO:0071141 SMAD protein complex(GO:0071141)
0.4 1.5 GO:0071012 U2-type catalytic step 1 spliceosome(GO:0071006) catalytic step 1 spliceosome(GO:0071012)
0.4 5.1 GO:0097651 phosphatidylinositol 3-kinase complex, class IB(GO:0005944) phosphatidylinositol 3-kinase complex, class I(GO:0097651)
0.4 2.6 GO:1990130 Iml1 complex(GO:1990130)
0.4 1.1 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.4 2.9 GO:0032783 ELL-EAF complex(GO:0032783)
0.4 1.4 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.3 3.1 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.3 2.8 GO:0071011 precatalytic spliceosome(GO:0071011)
0.3 1.7 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.3 3.8 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.3 7.0 GO:0031083 BLOC-1 complex(GO:0031083)
0.3 3.8 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.3 4.5 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.3 6.0 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.3 1.9 GO:0030891 VCB complex(GO:0030891)
0.3 3.4 GO:0030126 COPI vesicle coat(GO:0030126)
0.3 7.1 GO:0005686 U2 snRNP(GO:0005686)
0.3 7.9 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.3 11.4 GO:0031970 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.3 5.6 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.3 8.0 GO:0005680 anaphase-promoting complex(GO:0005680)
0.3 1.4 GO:0031501 mannosyltransferase complex(GO:0031501)
0.3 10.4 GO:0055038 recycling endosome membrane(GO:0055038)
0.3 2.2 GO:0031931 TORC1 complex(GO:0031931)
0.3 2.4 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.3 6.4 GO:0035102 PRC1 complex(GO:0035102)
0.3 1.0 GO:0061689 tricellular tight junction(GO:0061689)
0.3 1.5 GO:0033557 Slx1-Slx4 complex(GO:0033557)
0.2 25.8 GO:0016607 nuclear speck(GO:0016607)
0.2 2.4 GO:0015030 Cajal body(GO:0015030)
0.2 4.1 GO:0000813 ESCRT I complex(GO:0000813)
0.2 8.8 GO:0016605 PML body(GO:0016605)
0.2 2.3 GO:0000812 Swr1 complex(GO:0000812)
0.2 2.6 GO:0035101 FACT complex(GO:0035101)
0.2 1.4 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.2 2.5 GO:0030904 retromer complex(GO:0030904)
0.2 4.3 GO:0098844 postsynaptic endocytic zone membrane(GO:0098844)
0.2 1.1 GO:0034448 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.2 3.0 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.2 4.3 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.2 2.4 GO:0072546 ER membrane protein complex(GO:0072546)
0.2 0.9 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.2 2.5 GO:0016580 Sin3 complex(GO:0016580)
0.2 0.6 GO:0000138 Golgi trans cisterna(GO:0000138)
0.2 1.4 GO:0030892 nuclear cohesin complex(GO:0000798) mitotic cohesin complex(GO:0030892) nuclear mitotic cohesin complex(GO:0034990) nuclear meiotic cohesin complex(GO:0034991)
0.2 1.2 GO:0070449 elongin complex(GO:0070449)
0.2 3.7 GO:0005684 U2-type spliceosomal complex(GO:0005684)
0.2 0.4 GO:0031085 BLOC-3 complex(GO:0031085)
0.2 20.3 GO:0005802 trans-Golgi network(GO:0005802)
0.2 4.4 GO:0030667 secretory granule membrane(GO:0030667)
0.2 8.0 GO:0032587 ruffle membrane(GO:0032587)
0.2 9.7 GO:0031901 early endosome membrane(GO:0031901)
0.2 1.3 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.2 11.0 GO:0031228 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.2 14.9 GO:0098791 Golgi subcompartment(GO:0098791)
0.2 1.0 GO:0031258 lamellipodium membrane(GO:0031258)
0.2 4.0 GO:0005921 gap junction(GO:0005921)
0.2 2.3 GO:0030532 small nuclear ribonucleoprotein complex(GO:0030532)
0.2 1.0 GO:0031262 Ndc80 complex(GO:0031262)
0.2 8.1 GO:0005811 lipid particle(GO:0005811)
0.2 2.9 GO:0031932 TORC2 complex(GO:0031932)
0.2 1.6 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.1 7.3 GO:0072686 mitotic spindle(GO:0072686)
0.1 4.1 GO:0000145 exocyst(GO:0000145)
0.1 1.0 GO:0043194 axon initial segment(GO:0043194)
0.1 1.0 GO:0031371 ubiquitin conjugating enzyme complex(GO:0031371)
0.1 6.5 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.1 3.0 GO:0000781 chromosome, telomeric region(GO:0000781)
0.1 3.4 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 0.7 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.1 0.6 GO:0070390 transcription export complex 2(GO:0070390)
0.1 10.2 GO:0030027 lamellipodium(GO:0030027)
0.1 2.3 GO:0030057 desmosome(GO:0030057)
0.1 5.6 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.1 1.9 GO:0000178 exosome (RNase complex)(GO:0000178)
0.1 3.0 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.1 12.6 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.1 0.5 GO:0032838 cell projection cytoplasm(GO:0032838)
0.1 19.4 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.1 4.2 GO:0031105 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.1 8.0 GO:0005769 early endosome(GO:0005769)
0.1 11.6 GO:0031227 intrinsic component of endoplasmic reticulum membrane(GO:0031227)
0.1 1.7 GO:0035371 microtubule plus-end(GO:0035371)
0.1 2.9 GO:0008305 integrin complex(GO:0008305)
0.1 3.6 GO:0005902 microvillus(GO:0005902)
0.1 0.6 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.1 0.8 GO:0016272 prefoldin complex(GO:0016272)
0.1 4.0 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.1 1.1 GO:0005732 small nucleolar ribonucleoprotein complex(GO:0005732)
0.1 9.0 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.1 7.1 GO:0005871 kinesin complex(GO:0005871)
0.1 8.9 GO:0005925 focal adhesion(GO:0005925)
0.1 1.3 GO:0071564 npBAF complex(GO:0071564)
0.1 1.1 GO:0042555 MCM complex(GO:0042555)
0.1 5.9 GO:0019898 extrinsic component of membrane(GO:0019898)
0.1 1.3 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.1 2.5 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 1.5 GO:0005876 spindle microtubule(GO:0005876)
0.1 3.7 GO:0005681 spliceosomal complex(GO:0005681)
0.1 1.4 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.1 3.5 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.1 1.7 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 0.2 GO:0097361 CIA complex(GO:0097361)
0.1 5.5 GO:0005884 actin filament(GO:0005884)
0.1 14.1 GO:0000139 Golgi membrane(GO:0000139)
0.1 1.4 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.1 1.9 GO:0016528 sarcoplasm(GO:0016528) sarcoplasmic reticulum(GO:0016529)
0.1 15.9 GO:0005794 Golgi apparatus(GO:0005794)
0.0 3.7 GO:0000775 chromosome, centromeric region(GO:0000775)
0.0 3.5 GO:0098573 intrinsic component of mitochondrial membrane(GO:0098573)
0.0 12.7 GO:0030425 dendrite(GO:0030425)
0.0 9.5 GO:0000151 ubiquitin ligase complex(GO:0000151)
0.0 0.5 GO:0045095 keratin filament(GO:0045095)
0.0 2.4 GO:0036464 cytoplasmic ribonucleoprotein granule(GO:0036464)
0.0 0.0 GO:0005801 cis-Golgi network(GO:0005801)
0.0 25.7 GO:0005783 endoplasmic reticulum(GO:0005783)
0.0 2.1 GO:0031201 SNARE complex(GO:0031201)
0.0 1.8 GO:0016592 mediator complex(GO:0016592)
0.0 0.5 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 1.2 GO:0098978 glutamatergic synapse(GO:0098978)
0.0 0.2 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.6 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 2.1 GO:0016324 apical plasma membrane(GO:0016324)
0.0 14.0 GO:0005654 nucleoplasm(GO:0005654)
0.0 0.5 GO:0055037 recycling endosome(GO:0055037)
0.0 0.3 GO:0009925 basal plasma membrane(GO:0009925)
0.0 1.6 GO:0005764 lysosome(GO:0005764)
0.0 0.5 GO:0005861 troponin complex(GO:0005861)
0.0 1.4 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
4.1 16.4 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
3.0 14.9 GO:0016531 copper chaperone activity(GO:0016531)
2.6 7.7 GO:0043739 G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739)
2.3 9.2 GO:0008117 sphinganine-1-phosphate aldolase activity(GO:0008117)
2.2 6.6 GO:0071077 coenzyme A transmembrane transporter activity(GO:0015228) adenosine 3',5'-bisphosphate transmembrane transporter activity(GO:0071077) AMP transmembrane transporter activity(GO:0080122)
1.8 7.4 GO:0030366 molybdopterin synthase activity(GO:0030366)
1.8 7.4 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
1.7 8.4 GO:0004307 ethanolaminephosphotransferase activity(GO:0004307)
1.6 4.9 GO:0047760 medium-chain fatty acid-CoA ligase activity(GO:0031956) butyrate-CoA ligase activity(GO:0047760)
1.6 6.5 GO:0016822 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
1.5 4.5 GO:0016743 carboxyl- or carbamoyltransferase activity(GO:0016743)
1.5 5.8 GO:0003979 UDP-glucose 6-dehydrogenase activity(GO:0003979)
1.4 4.2 GO:0004113 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity(GO:0004113)
1.3 4.0 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
1.3 6.6 GO:0035197 siRNA binding(GO:0035197)
1.3 8.8 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
1.3 3.8 GO:0052833 inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
1.2 8.3 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
1.2 5.9 GO:1990189 peptide-serine-N-acetyltransferase activity(GO:1990189)
1.2 5.9 GO:0035514 DNA demethylase activity(GO:0035514)
1.1 6.8 GO:0070016 armadillo repeat domain binding(GO:0070016)
1.1 3.4 GO:0003919 FMN adenylyltransferase activity(GO:0003919)
1.1 5.5 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
1.1 3.3 GO:0071532 ankyrin repeat binding(GO:0071532)
1.1 2.2 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
1.1 3.2 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
1.1 6.5 GO:0022889 serine transmembrane transporter activity(GO:0022889)
1.0 15.4 GO:2001069 glycogen binding(GO:2001069)
1.0 3.0 GO:0030623 U5 snRNA binding(GO:0030623)
1.0 4.9 GO:0016429 tRNA (adenine-N1-)-methyltransferase activity(GO:0016429)
1.0 7.8 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
1.0 3.9 GO:0071253 connexin binding(GO:0071253)
0.9 2.8 GO:0043621 protein self-association(GO:0043621)
0.9 4.7 GO:0001735 prenylcysteine oxidase activity(GO:0001735)
0.9 2.8 GO:0004776 succinate-CoA ligase activity(GO:0004774) succinate-CoA ligase (ADP-forming) activity(GO:0004775) succinate-CoA ligase (GDP-forming) activity(GO:0004776)
0.9 3.5 GO:0004361 glutaryl-CoA dehydrogenase activity(GO:0004361)
0.9 2.6 GO:0001734 mRNA (N6-adenosine)-methyltransferase activity(GO:0001734)
0.8 4.2 GO:0050218 propionate-CoA ligase activity(GO:0050218)
0.8 3.2 GO:0008488 gamma-glutamyl carboxylase activity(GO:0008488)
0.8 4.7 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.8 8.5 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.8 2.3 GO:0008489 UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity(GO:0008489)
0.7 2.2 GO:0019777 Atg12 transferase activity(GO:0019777)
0.7 3.7 GO:0004001 adenosine kinase activity(GO:0004001)
0.7 4.4 GO:0008126 acetylesterase activity(GO:0008126)
0.7 5.7 GO:0005351 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402) sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.7 10.6 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.7 2.1 GO:0004394 heparan sulfate 2-O-sulfotransferase activity(GO:0004394)
0.7 16.2 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.7 6.3 GO:0016783 sulfurtransferase activity(GO:0016783)
0.7 4.9 GO:0035252 UDP-xylosyltransferase activity(GO:0035252)
0.7 9.6 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.7 2.0 GO:0003978 UDP-glucose 4-epimerase activity(GO:0003978)
0.7 2.0 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.7 4.6 GO:0000995 transcription factor activity, core RNA polymerase III binding(GO:0000995)
0.7 6.6 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.7 3.3 GO:0015117 thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131) malate transmembrane transporter activity(GO:0015140)
0.6 2.6 GO:0003958 NADPH-hemoprotein reductase activity(GO:0003958)
0.6 1.9 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.6 2.5 GO:0004579 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.6 5.5 GO:1904047 S-adenosyl-L-methionine binding(GO:1904047)
0.6 3.0 GO:1990756 protein binding, bridging involved in substrate recognition for ubiquitination(GO:1990756)
0.6 5.5 GO:0008420 CTD phosphatase activity(GO:0008420)
0.6 9.6 GO:0004724 magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
0.6 2.4 GO:0102344 3-hydroxyacyl-CoA dehydratase activity(GO:0018812) 3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345)
0.6 2.9 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.6 5.6 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.5 2.7 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.5 3.8 GO:0004407 histone deacetylase activity(GO:0004407) NAD-dependent histone deacetylase activity(GO:0017136)
0.5 3.3 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.5 9.7 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.5 2.1 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.5 3.7 GO:0070698 type I activin receptor binding(GO:0070698)
0.5 3.6 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.5 8.7 GO:0045159 myosin II binding(GO:0045159)
0.5 3.4 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.5 2.4 GO:0032183 SUMO binding(GO:0032183)
0.5 1.0 GO:0070883 pre-miRNA binding(GO:0070883)
0.5 2.4 GO:0016878 acid-thiol ligase activity(GO:0016878)
0.5 1.9 GO:0004092 carnitine O-acetyltransferase activity(GO:0004092)
0.5 3.2 GO:0016880 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.5 5.5 GO:0000217 DNA secondary structure binding(GO:0000217)
0.4 1.8 GO:0004419 hydroxymethylglutaryl-CoA lyase activity(GO:0004419)
0.4 1.8 GO:0034511 U3 snoRNA binding(GO:0034511)
0.4 2.2 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.4 1.7 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.4 4.6 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.4 2.9 GO:0004630 phospholipase D activity(GO:0004630)
0.4 2.9 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.4 1.2 GO:0008179 adenylate cyclase binding(GO:0008179)
0.4 7.7 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.4 1.2 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.4 3.2 GO:0070137 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.4 1.2 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.4 2.8 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.4 2.3 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.4 2.3 GO:0004418 hydroxymethylbilane synthase activity(GO:0004418)
0.4 1.5 GO:0047611 acetylspermidine deacetylase activity(GO:0047611)
0.4 4.4 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.4 1.1 GO:0004342 glucosamine-6-phosphate deaminase activity(GO:0004342)
0.4 2.9 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.4 4.4 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.4 7.2 GO:0070411 I-SMAD binding(GO:0070411)
0.4 2.5 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.4 2.5 GO:0008118 N-acetyllactosaminide alpha-2,3-sialyltransferase activity(GO:0008118)
0.3 3.1 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.3 2.7 GO:0072518 Rho-dependent protein serine/threonine kinase activity(GO:0072518)
0.3 3.0 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062) collagen receptor activity(GO:0038064)
0.3 2.6 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.3 5.2 GO:0031386 protein tag(GO:0031386)
0.3 6.4 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.3 3.8 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.3 0.9 GO:0047804 cysteine-S-conjugate beta-lyase activity(GO:0047804)
0.3 4.4 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.3 2.5 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.3 3.4 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.3 4.2 GO:0034595 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439) phosphatidylinositol phosphate 5-phosphatase activity(GO:0034595)
0.3 1.5 GO:0004619 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619)
0.3 2.1 GO:0035173 histone kinase activity(GO:0035173)
0.3 20.5 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.3 2.1 GO:0061650 ubiquitin-like protein conjugating enzyme activity(GO:0061650)
0.3 3.2 GO:0052812 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812)
0.3 2.9 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.3 1.1 GO:0004473 malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.3 3.7 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.3 6.7 GO:0031267 small GTPase binding(GO:0031267)
0.3 7.2 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.3 5.6 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.3 4.8 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.3 3.9 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.3 1.8 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.3 5.2 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.3 1.0 GO:0004379 glycylpeptide N-tetradecanoyltransferase activity(GO:0004379)
0.3 8.4 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.2 8.2 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.2 3.2 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.2 1.2 GO:0043139 5'-3' DNA helicase activity(GO:0043139)
0.2 1.7 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.2 2.2 GO:0045294 alpha-catenin binding(GO:0045294)
0.2 8.7 GO:0019003 GDP binding(GO:0019003)
0.2 2.3 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.2 3.5 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.2 1.5 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.2 8.8 GO:0000049 tRNA binding(GO:0000049)
0.2 9.3 GO:0071949 FAD binding(GO:0071949)
0.2 1.5 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.2 5.0 GO:0003688 DNA replication origin binding(GO:0003688)
0.2 4.1 GO:0016854 racemase and epimerase activity(GO:0016854)
0.2 1.2 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.2 6.3 GO:0042162 telomeric DNA binding(GO:0042162)
0.2 2.8 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.2 1.6 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.2 1.2 GO:0004743 pyruvate kinase activity(GO:0004743)
0.2 1.7 GO:0043515 kinetochore binding(GO:0043515)
0.2 2.3 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.2 6.2 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.2 1.3 GO:0034057 RNA strand annealing activity(GO:0033592) RNA strand-exchange activity(GO:0034057)
0.2 2.0 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.2 1.3 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.2 0.5 GO:0008119 thiopurine S-methyltransferase activity(GO:0008119)
0.2 1.1 GO:0030332 cyclin binding(GO:0030332)
0.2 15.1 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.2 2.5 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.2 7.2 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.2 2.9 GO:0045134 guanosine-diphosphatase activity(GO:0004382) uridine-diphosphatase activity(GO:0045134)
0.2 2.2 GO:0005537 mannose binding(GO:0005537)
0.2 4.0 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.2 0.7 GO:0033204 ribonuclease P RNA binding(GO:0033204)
0.2 4.4 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.2 0.5 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.2 2.4 GO:0005123 death receptor binding(GO:0005123)
0.2 4.0 GO:0004659 prenyltransferase activity(GO:0004659)
0.2 1.0 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.2 2.9 GO:0004532 3'-5'-exoribonuclease activity(GO:0000175) exoribonuclease activity(GO:0004532) exoribonuclease activity, producing 5'-phosphomonoesters(GO:0016896)
0.2 4.9 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.2 0.6 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.2 2.5 GO:0008301 DNA binding, bending(GO:0008301)
0.2 1.9 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.2 1.2 GO:0015168 glycerol transmembrane transporter activity(GO:0015168)
0.2 4.7 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.2 2.0 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.1 2.2 GO:0019213 deacetylase activity(GO:0019213)
0.1 1.2 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.1 1.8 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) cysteine-type endopeptidase regulator activity involved in apoptotic process(GO:0043028)
0.1 1.4 GO:0005042 netrin receptor activity(GO:0005042)
0.1 0.8 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.1 3.3 GO:0005112 Notch binding(GO:0005112)
0.1 0.8 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.1 1.4 GO:0043495 protein anchor(GO:0043495)
0.1 12.1 GO:0019905 syntaxin binding(GO:0019905)
0.1 2.2 GO:0035497 cAMP response element binding(GO:0035497)
0.1 1.1 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.1 1.3 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.1 7.3 GO:0003697 single-stranded DNA binding(GO:0003697)
0.1 18.6 GO:0035091 phosphatidylinositol binding(GO:0035091)
0.1 1.2 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.1 2.4 GO:0004467 long-chain fatty acid-CoA ligase activity(GO:0004467)
0.1 5.2 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.1 1.3 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.1 23.2 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 5.0 GO:0030170 pyridoxal phosphate binding(GO:0030170)
0.1 1.4 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.1 4.3 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1 2.7 GO:0030165 PDZ domain binding(GO:0030165)
0.1 1.0 GO:0052650 alcohol dehydrogenase (NADP+) activity(GO:0008106) NADP-retinol dehydrogenase activity(GO:0052650)
0.1 2.4 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.1 2.0 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 0.6 GO:0004997 thyrotropin-releasing hormone receptor activity(GO:0004997)
0.1 2.2 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.1 8.9 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.1 1.0 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 1.8 GO:0097602 cullin family protein binding(GO:0097602)
0.1 4.4 GO:0031491 nucleosome binding(GO:0031491)
0.1 2.7 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 0.5 GO:1903924 estradiol binding(GO:1903924)
0.1 1.2 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
0.1 2.8 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 1.4 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.1 2.2 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
0.1 2.1 GO:0008307 structural constituent of muscle(GO:0008307)
0.1 12.9 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.1 2.4 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1 2.8 GO:0004629 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.1 1.0 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.1 2.0 GO:0046332 SMAD binding(GO:0046332)
0.1 0.2 GO:0015350 reduced folate carrier activity(GO:0008518) methotrexate transporter activity(GO:0015350)
0.1 10.6 GO:0060090 binding, bridging(GO:0060090)
0.1 0.6 GO:0008494 translation activator activity(GO:0008494)
0.1 4.3 GO:0017124 SH3 domain binding(GO:0017124)
0.1 0.2 GO:0001635 adrenomedullin receptor activity(GO:0001605) calcitonin gene-related peptide receptor activity(GO:0001635)
0.1 6.3 GO:0019208 phosphatase regulator activity(GO:0019208)
0.1 0.6 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.1 1.0 GO:0016279 lysine N-methyltransferase activity(GO:0016278) protein-lysine N-methyltransferase activity(GO:0016279)
0.1 1.3 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.1 3.1 GO:0003725 double-stranded RNA binding(GO:0003725)
0.1 0.9 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 5.7 GO:0004519 endonuclease activity(GO:0004519)
0.1 3.1 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.1 1.1 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.1 1.3 GO:0008175 tRNA methyltransferase activity(GO:0008175)
0.1 0.5 GO:0030172 troponin C binding(GO:0030172) troponin I binding(GO:0031013)
0.1 0.4 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.1 3.4 GO:0030276 clathrin binding(GO:0030276)
0.1 10.0 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.1 3.1 GO:0005319 lipid transporter activity(GO:0005319)
0.1 0.4 GO:0015232 heme transporter activity(GO:0015232)
0.1 3.2 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.1 2.7 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.1 6.1 GO:0003714 transcription corepressor activity(GO:0003714)
0.1 3.2 GO:0000149 SNARE binding(GO:0000149)
0.1 2.0 GO:0004180 carboxypeptidase activity(GO:0004180)
0.0 2.4 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 0.2 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 18.0 GO:0008289 lipid binding(GO:0008289)
0.0 1.4 GO:0051018 protein kinase A binding(GO:0051018)
0.0 15.0 GO:0030695 GTPase regulator activity(GO:0030695)
0.0 3.6 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 7.4 GO:0042802 identical protein binding(GO:0042802)
0.0 1.4 GO:0008013 beta-catenin binding(GO:0008013)
0.0 23.7 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 1.3 GO:1901682 sulfur compound transmembrane transporter activity(GO:1901682)
0.0 0.0 GO:0070325 low-density lipoprotein particle receptor binding(GO:0050750) lipoprotein particle receptor binding(GO:0070325)
0.0 1.0 GO:0015379 cation:chloride symporter activity(GO:0015377) potassium:chloride symporter activity(GO:0015379)
0.0 1.4 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 7.4 GO:0003729 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 1.2 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.3 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 0.3 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
0.0 0.3 GO:0004376 glycolipid mannosyltransferase activity(GO:0004376)
0.0 8.8 GO:0051015 actin filament binding(GO:0051015)
0.0 0.7 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 0.2 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 1.2 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.0 0.6 GO:0017069 snRNA binding(GO:0017069)
0.0 0.4 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.3 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 1.7 GO:0003724 RNA helicase activity(GO:0003724)
0.0 0.2 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.0 0.6 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.7 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 2.4 GO:0005262 calcium channel activity(GO:0005262)
0.0 0.4 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.7 GO:0044325 ion channel binding(GO:0044325)
0.0 0.1 GO:0008502 melatonin receptor activity(GO:0008502)
0.0 0.3 GO:0004875 complement receptor activity(GO:0004875)
0.0 0.1 GO:0001607 neuromedin U receptor activity(GO:0001607)
0.0 4.9 GO:0003924 GTPase activity(GO:0003924)
0.0 0.8 GO:0004620 phospholipase activity(GO:0004620)
0.0 0.2 GO:0046875 ephrin receptor binding(GO:0046875)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 8.9 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
1.0 5.0 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.6 0.6 PID S1P S1P1 PATHWAY S1P1 pathway
0.5 8.0 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.5 11.0 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.4 4.0 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.4 7.4 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.4 3.5 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.4 5.9 PID ALK2 PATHWAY ALK2 signaling events
0.4 6.6 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.4 7.3 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.4 18.4 PID PI3KCI PATHWAY Class I PI3K signaling events
0.4 2.5 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.4 3.2 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.3 18.8 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.3 2.4 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.3 3.1 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.3 4.6 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.3 5.1 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.2 5.4 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.2 7.4 PID FOXO PATHWAY FoxO family signaling
0.2 5.6 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.2 4.2 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.2 2.0 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.2 1.4 ST B CELL ANTIGEN RECEPTOR B Cell Antigen Receptor
0.2 3.1 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.2 10.7 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.2 1.9 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.2 2.2 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.2 2.0 PID EPO PATHWAY EPO signaling pathway
0.2 4.2 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.2 6.1 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.1 2.2 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.1 0.8 ST G ALPHA S PATHWAY G alpha s Pathway
0.1 3.3 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.1 3.3 PID INSULIN PATHWAY Insulin Pathway
0.1 2.1 PID ARF 3PATHWAY Arf1 pathway
0.1 2.5 PID IL12 2PATHWAY IL12-mediated signaling events
0.1 1.0 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.1 1.3 PID LPA4 PATHWAY LPA4-mediated signaling events
0.1 0.8 ST GA12 PATHWAY G alpha 12 Pathway
0.1 0.9 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.1 1.6 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.1 1.4 PID TNF PATHWAY TNF receptor signaling pathway
0.1 3.8 PID AR PATHWAY Coregulation of Androgen receptor activity
0.1 2.1 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 1.2 PID MYC PATHWAY C-MYC pathway
0.1 0.5 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 1.2 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 1.9 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 1.6 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.9 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 1.6 PID CMYB PATHWAY C-MYB transcription factor network
0.0 0.7 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.4 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.7 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.5 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.1 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 3.2 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.6 PID P73PATHWAY p73 transcription factor network
0.0 0.9 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 5.5 REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat
1.3 11.9 REACTOME ARMS MEDIATED ACTIVATION Genes involved in ARMS-mediated activation
0.8 4.2 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.7 10.6 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.6 2.5 REACTOME GENERIC TRANSCRIPTION PATHWAY Genes involved in Generic Transcription Pathway
0.6 6.4 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.6 17.8 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.6 4.4 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.6 7.2 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.6 7.7 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.5 4.2 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.5 6.1 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.5 5.3 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.5 4.3 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.5 9.5 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.5 4.6 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.4 9.6 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.4 8.5 REACTOME PHOSPHORYLATION OF THE APC C Genes involved in Phosphorylation of the APC/C
0.4 5.8 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.4 1.2 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.4 0.8 REACTOME NGF SIGNALLING VIA TRKA FROM THE PLASMA MEMBRANE Genes involved in NGF signalling via TRKA from the plasma membrane
0.4 6.0 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.4 3.2 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.4 4.3 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.3 18.9 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.3 6.3 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.3 7.1 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.3 3.8 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.3 1.3 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.3 1.9 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.3 4.0 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.3 2.9 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.3 11.8 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.3 1.7 REACTOME PROCESSIVE SYNTHESIS ON THE LAGGING STRAND Genes involved in Processive synthesis on the lagging strand
0.3 1.7 REACTOME EARLY PHASE OF HIV LIFE CYCLE Genes involved in Early Phase of HIV Life Cycle
0.3 2.8 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.3 1.4 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.3 7.0 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.3 4.6 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.3 5.8 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation
0.3 4.1 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.3 9.8 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.3 8.2 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.2 3.0 REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.2 3.7 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.2 2.1 REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION Genes involved in Cyclin E associated events during G1/S transition
0.2 3.3 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.2 0.9 REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.2 2.2 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.2 1.9 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.2 3.8 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.2 0.6 REACTOME SHC RELATED EVENTS Genes involved in SHC-related events
0.2 4.9 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.2 1.6 REACTOME FORMATION OF THE HIV1 EARLY ELONGATION COMPLEX Genes involved in Formation of the HIV-1 Early Elongation Complex
0.2 4.3 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.2 8.0 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.2 2.3 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.2 1.9 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.2 3.7 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.2 0.9 REACTOME CD28 DEPENDENT PI3K AKT SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.2 2.0 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.2 3.0 REACTOME TELOMERE MAINTENANCE Genes involved in Telomere Maintenance
0.2 6.8 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.2 6.2 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.2 4.8 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.2 1.6 REACTOME SIGNALING BY NOTCH4 Genes involved in Signaling by NOTCH4
0.1 2.1 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.1 1.5 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.1 11.7 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.1 1.6 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.1 1.4 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.1 1.0 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.1 2.5 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.1 4.0 REACTOME CLEAVAGE OF GROWING TRANSCRIPT IN THE TERMINATION REGION Genes involved in Cleavage of Growing Transcript in the Termination Region
0.1 2.3 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.1 1.6 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.1 1.5 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.1 1.2 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.1 0.8 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.1 1.9 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.1 0.8 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.1 0.6 REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.1 1.4 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.1 0.7 REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
0.1 1.8 REACTOME PI3K AKT ACTIVATION Genes involved in PI3K/AKT activation
0.1 2.8 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.1 0.7 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.1 0.7 REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS Genes involved in TGF-beta receptor signaling activates SMADs
0.1 1.3 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.1 3.3 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.1 3.8 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.1 0.6 REACTOME TRAF6 MEDIATED NFKB ACTIVATION Genes involved in TRAF6 mediated NF-kB activation
0.1 6.0 REACTOME PROCESSING OF CAPPED INTRON CONTAINING PRE MRNA Genes involved in Processing of Capped Intron-Containing Pre-mRNA
0.1 2.9 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.1 1.5 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 2.2 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.1 0.6 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.1 1.0 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.1 2.6 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.1 1.9 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.1 0.3 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1 1.0 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 1.6 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.4 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.2 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.6 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.0 0.4 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.0 0.4 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.3 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.1 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.7 REACTOME TOLL RECEPTOR CASCADES Genes involved in Toll Receptor Cascades
0.0 0.2 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.1 REACTOME RESOLUTION OF AP SITES VIA THE MULTIPLE NUCLEOTIDE PATCH REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the multiple-nucleotide patch replacement pathway
0.0 0.1 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions