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PRJNA438478: RNAseq of wild type zebrafish germline
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Results for en1b_en2a+en2b_gbx1_emx1
Z-value: 0.78
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Transcription factors associated with en1b_en2a+en2b_gbx1_emx1
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
en1b
|
ENSDARG00000098730 | engrailed homeobox 1b |
|
en2a
|
ENSDARG00000026599 | engrailed homeobox 2a |
|
en2b
|
ENSDARG00000038868 | engrailed homeobox 2b |
|
en2a
|
ENSDARG00000115233 | engrailed homeobox 2a |
|
gbx1
|
ENSDARG00000071418 | gastrulation brain homeobox 1 |
|
emx1
|
ENSDARG00000039569 | empty spiracles homeobox 1 |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| en2a | dr11_v1_chr7_-_40993456_40993456 | -0.96 | 3.0e-10 | Click! |
| en2b | dr11_v1_chr2_+_29976419_29976419 | -0.96 | 5.1e-10 | Click! |
| en1b | dr11_v1_chr1_+_7679328_7679328 | -0.86 | 4.6e-06 | Click! |
| emx1 | dr11_v1_chr13_+_15004398_15004398 | 0.36 | 1.4e-01 | Click! |
| gbx1 | dr11_v1_chr24_+_34113424_34113424 | -0.26 | 3.1e-01 | Click! |
Activity profile of en1b_en2a+en2b_gbx1_emx1 motif
Sorted Z-values of en1b_en2a+en2b_gbx1_emx1 motif
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr21_+_25777425 | 6.91 |
ENSDART00000021620
|
cldnd
|
claudin d |
| chr9_-_35633827 | 5.50 |
ENSDART00000077745
|
zp2l1
|
zona pellucida glycoprotein 2, like 1 |
| chr10_-_21362071 | 5.46 |
ENSDART00000125167
|
avd
|
avidin |
| chr10_-_21362320 | 5.11 |
ENSDART00000189789
|
avd
|
avidin |
| chr20_-_23426339 | 4.64 |
ENSDART00000004625
|
zar1
|
zygote arrest 1 |
| chr1_-_55248496 | 4.02 |
ENSDART00000098615
|
nanos3
|
nanos homolog 3 |
| chr18_-_40708537 | 3.98 |
ENSDART00000077577
|
si:ch211-132b12.8
|
si:ch211-132b12.8 |
| chr6_+_21001264 | 3.77 |
ENSDART00000044519
ENSDART00000151278 |
cx44.2
|
connexin 44.2 |
| chr10_-_34002185 | 3.52 |
ENSDART00000046599
|
zar1l
|
zygote arrest 1-like |
| chr2_+_6253246 | 3.32 |
ENSDART00000058256
ENSDART00000076700 |
zp3b
|
zona pellucida glycoprotein 3b |
| chr24_-_9979342 | 3.23 |
ENSDART00000138576
ENSDART00000191206 |
zgc:171977
|
zgc:171977 |
| chr11_-_44801968 | 3.00 |
ENSDART00000161846
|
map1lc3c
|
microtubule-associated protein 1 light chain 3 gamma |
| chr5_+_29794058 | 2.94 |
ENSDART00000045410
|
thy1
|
Thy-1 cell surface antigen |
| chr17_+_16046132 | 2.90 |
ENSDART00000155005
|
si:ch73-204p21.2
|
si:ch73-204p21.2 |
| chr17_+_16046314 | 2.78 |
ENSDART00000154554
ENSDART00000154338 ENSDART00000155336 |
si:ch73-204p21.2
|
si:ch73-204p21.2 |
| chr10_+_16036246 | 2.72 |
ENSDART00000141586
ENSDART00000135868 ENSDART00000065037 ENSDART00000124502 |
lmnb1
|
lamin B1 |
| chr22_+_17828267 | 2.51 |
ENSDART00000136016
|
hapln4
|
hyaluronan and proteoglycan link protein 4 |
| chr8_-_23780334 | 2.44 |
ENSDART00000145179
ENSDART00000145894 |
zgc:195245
|
zgc:195245 |
| chr12_-_48168135 | 2.43 |
ENSDART00000186624
|
pald1a
|
phosphatase domain containing, paladin 1a |
| chr10_+_15255198 | 2.41 |
ENSDART00000139047
ENSDART00000172107 ENSDART00000183413 ENSDART00000185314 |
vldlr
|
very low density lipoprotein receptor |
| chr19_+_31585917 | 2.40 |
ENSDART00000132182
|
gmnn
|
geminin, DNA replication inhibitor |
| chr11_-_1550709 | 2.17 |
ENSDART00000110097
|
si:ch73-303b9.1
|
si:ch73-303b9.1 |
| chr11_+_18183220 | 2.08 |
ENSDART00000113468
|
LO018315.10
|
|
| chr23_+_2728095 | 2.03 |
ENSDART00000066086
|
zgc:114123
|
zgc:114123 |
| chr6_+_28208973 | 1.98 |
ENSDART00000171216
ENSDART00000171377 ENSDART00000167389 ENSDART00000166988 |
LSM2 (1 of many)
|
si:ch73-14h10.2 |
| chr10_-_44560165 | 1.94 |
ENSDART00000181217
ENSDART00000076084 |
npm2b
|
nucleophosmin/nucleoplasmin, 2b |
| chr1_-_18811517 | 1.90 |
ENSDART00000142026
|
si:dkey-167i21.2
|
si:dkey-167i21.2 |
| chr11_+_37638873 | 1.90 |
ENSDART00000186384
ENSDART00000184291 ENSDART00000131782 ENSDART00000140502 |
sh2d5
|
SH2 domain containing 5 |
| chr5_-_30074332 | 1.90 |
ENSDART00000147963
|
bco2a
|
beta-carotene oxygenase 2a |
| chr10_+_19596214 | 1.89 |
ENSDART00000183110
|
CABZ01059626.1
|
|
| chr11_-_6452444 | 1.79 |
ENSDART00000137879
ENSDART00000134957 ENSDART00000004483 |
larp6b
|
La ribonucleoprotein domain family, member 6b |
| chr12_-_14143344 | 1.77 |
ENSDART00000152742
|
buc2l
|
bucky ball 2-like |
| chr14_+_34490445 | 1.68 |
ENSDART00000132193
ENSDART00000148044 |
wnt8a
|
wingless-type MMTV integration site family, member 8a |
| chr3_+_22035863 | 1.66 |
ENSDART00000177169
|
cdc27
|
cell division cycle 27 |
| chr17_+_21902058 | 1.62 |
ENSDART00000142178
|
plekha1a
|
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1a |
| chr2_-_15324837 | 1.59 |
ENSDART00000015655
|
tecrl2b
|
trans-2,3-enoyl-CoA reductase-like 2b |
| chr3_+_28860283 | 1.52 |
ENSDART00000077235
|
alg1
|
ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase |
| chr22_+_4488454 | 1.50 |
ENSDART00000170620
|
ctxn1
|
cortexin 1 |
| chr24_+_12835935 | 1.49 |
ENSDART00000114762
|
nanog
|
nanog homeobox |
| chr16_+_47207691 | 1.48 |
ENSDART00000062507
|
ica1
|
islet cell autoantigen 1 |
| chr9_-_50000144 | 1.45 |
ENSDART00000123416
|
scn1a
|
sodium channel, voltage-gated, type I, alpha |
| chr12_-_33357655 | 1.43 |
ENSDART00000066233
ENSDART00000148165 |
slc16a3
|
solute carrier family 16 (monocarboxylate transporter), member 3 |
| chr14_+_8940326 | 1.42 |
ENSDART00000159920
|
rps6kal
|
ribosomal protein S6 kinase a, like |
| chr10_+_15255012 | 1.39 |
ENSDART00000023766
|
vldlr
|
very low density lipoprotein receptor |
| chr8_-_25034411 | 1.35 |
ENSDART00000135973
|
nfyal
|
nuclear transcription factor Y, alpha, like |
| chr20_-_6532462 | 1.34 |
ENSDART00000054653
|
mcm3l
|
MCM3 minichromosome maintenance deficient 3 (S. cerevisiae), like |
| chr24_-_24724233 | 1.31 |
ENSDART00000127044
ENSDART00000012399 |
armc1
|
armadillo repeat containing 1 |
| chr21_+_34088110 | 1.25 |
ENSDART00000145123
ENSDART00000029599 ENSDART00000147519 |
mtmr1b
|
myotubularin related protein 1b |
| chr5_-_15283509 | 1.22 |
ENSDART00000052712
|
gnb1l
|
guanine nucleotide binding protein (G protein), beta polypeptide 1-like |
| chr21_-_32060993 | 1.18 |
ENSDART00000131651
|
si:ch211-160j14.2
|
si:ch211-160j14.2 |
| chr24_-_2450597 | 1.18 |
ENSDART00000188080
ENSDART00000093331 |
rreb1a
|
ras responsive element binding protein 1a |
| chr2_+_41526904 | 1.18 |
ENSDART00000127520
|
acvr1l
|
activin A receptor, type 1 like |
| chr17_-_40956035 | 1.17 |
ENSDART00000124715
|
si:dkey-16j16.4
|
si:dkey-16j16.4 |
| chr12_+_46582727 | 1.15 |
ENSDART00000149326
|
ush1gb
|
Usher syndrome 1Gb (autosomal recessive) |
| chr10_-_35257458 | 1.14 |
ENSDART00000143890
ENSDART00000139107 ENSDART00000082445 |
prr11
|
proline rich 11 |
| chr21_-_39177564 | 1.13 |
ENSDART00000065143
|
unc119b
|
unc-119 homolog b (C. elegans) |
| chr8_-_1838315 | 1.10 |
ENSDART00000114476
ENSDART00000140077 |
pi4kab
|
phosphatidylinositol 4-kinase, catalytic, alpha b |
| chr2_-_38287987 | 1.09 |
ENSDART00000185329
ENSDART00000061677 |
si:ch211-14a17.6
|
si:ch211-14a17.6 |
| chr24_-_41320037 | 1.08 |
ENSDART00000129058
|
rheb
|
Ras homolog, mTORC1 binding |
| chr23_+_28322986 | 1.08 |
ENSDART00000134710
|
birc5b
|
baculoviral IAP repeat containing 5b |
| chr22_-_23267893 | 1.08 |
ENSDART00000105613
|
si:dkey-121a9.3
|
si:dkey-121a9.3 |
| chr19_-_19871211 | 1.07 |
ENSDART00000170980
|
evx1
|
even-skipped homeobox 1 |
| chr7_-_51773166 | 1.05 |
ENSDART00000054591
|
bmp15
|
bone morphogenetic protein 15 |
| chr13_+_38814521 | 1.05 |
ENSDART00000110976
|
col19a1
|
collagen, type XIX, alpha 1 |
| chr6_-_37744430 | 1.03 |
ENSDART00000150177
ENSDART00000149722 |
nipa2
|
non imprinted in Prader-Willi/Angelman syndrome 2 (human) |
| chr24_+_19415124 | 1.02 |
ENSDART00000186931
|
sulf1
|
sulfatase 1 |
| chr24_-_10006158 | 1.02 |
ENSDART00000106244
|
zgc:171750
|
zgc:171750 |
| chr2_+_1714640 | 1.02 |
ENSDART00000086761
ENSDART00000111613 |
adgrl2b.1
adgrl2b.1
|
adhesion G protein-coupled receptor L2b, tandem duplicate 1 adhesion G protein-coupled receptor L2b, tandem duplicate 1 |
| chr20_-_14114078 | 1.01 |
ENSDART00000168434
ENSDART00000104032 |
si:ch211-223m11.2
|
si:ch211-223m11.2 |
| chr15_+_28410664 | 1.01 |
ENSDART00000132028
ENSDART00000057697 ENSDART00000057257 |
pitpnaa
|
phosphatidylinositol transfer protein, alpha a |
| chr1_+_513986 | 1.01 |
ENSDART00000109083
ENSDART00000081945 |
txnl4b
|
thioredoxin-like 4B |
| chr8_-_32385989 | 1.00 |
ENSDART00000143716
ENSDART00000098850 |
lipg
|
lipase, endothelial |
| chr8_-_15129573 | 0.99 |
ENSDART00000142358
|
bcar3
|
BCAR3, NSP family adaptor protein |
| chr19_-_25119443 | 0.96 |
ENSDART00000148953
|
ptp4a3
|
protein tyrosine phosphatase type IVA, member 3 |
| chr20_+_27087539 | 0.95 |
ENSDART00000062094
|
tmem251
|
transmembrane protein 251 |
| chr6_-_3982783 | 0.95 |
ENSDART00000171944
|
slc25a12
|
solute carrier family 25 (aspartate/glutamate carrier), member 12 |
| chr1_-_513762 | 0.90 |
ENSDART00000148162
ENSDART00000144606 |
trmt10c
|
tRNA methyltransferase 10C, mitochondrial RNase P subunit |
| chr11_-_42134968 | 0.90 |
ENSDART00000187115
|
FP325130.1
|
|
| chr19_-_8768564 | 0.89 |
ENSDART00000170416
|
si:ch73-350k19.1
|
si:ch73-350k19.1 |
| chr6_+_40922572 | 0.89 |
ENSDART00000133599
ENSDART00000002728 ENSDART00000145153 |
eif4enif1
|
eukaryotic translation initiation factor 4E nuclear import factor 1 |
| chr2_-_57076687 | 0.87 |
ENSDART00000161523
|
slc25a42
|
solute carrier family 25, member 42 |
| chr7_+_24528430 | 0.87 |
ENSDART00000133022
|
si:dkeyp-75h12.2
|
si:dkeyp-75h12.2 |
| chr10_+_17371356 | 0.86 |
ENSDART00000122663
|
sppl3
|
signal peptide peptidase 3 |
| chr12_+_46582168 | 0.86 |
ENSDART00000189402
|
ush1gb
|
Usher syndrome 1Gb (autosomal recessive) |
| chr10_+_7709724 | 0.86 |
ENSDART00000097670
|
ggcx
|
gamma-glutamyl carboxylase |
| chr20_+_53181017 | 0.86 |
ENSDART00000189692
ENSDART00000177109 |
FIG4
|
FIG4 phosphoinositide 5-phosphatase |
| chr24_-_34680956 | 0.86 |
ENSDART00000171009
|
ctnna1
|
catenin (cadherin-associated protein), alpha 1 |
| chr5_-_23715861 | 0.86 |
ENSDART00000019992
|
gbgt1l1
|
globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 1 |
| chr5_+_41476443 | 0.85 |
ENSDART00000145228
ENSDART00000137981 ENSDART00000142538 |
pias2
|
protein inhibitor of activated STAT, 2 |
| chr14_-_33945692 | 0.84 |
ENSDART00000168546
ENSDART00000189778 |
zdhhc24
|
zinc finger, DHHC-type containing 24 |
| chr25_-_32869794 | 0.83 |
ENSDART00000162784
|
tmem266
|
transmembrane protein 266 |
| chr12_+_22580579 | 0.83 |
ENSDART00000171725
ENSDART00000192290 |
capgb
|
capping protein (actin filament), gelsolin-like b |
| chr17_+_37227936 | 0.83 |
ENSDART00000076009
|
hadhab
|
hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha b |
| chr23_-_36446307 | 0.82 |
ENSDART00000136623
|
zgc:174906
|
zgc:174906 |
| chr8_-_50888806 | 0.82 |
ENSDART00000053750
|
acsl2
|
acyl-CoA synthetase long chain family member 2 |
| chr12_-_33817114 | 0.80 |
ENSDART00000161265
|
twnk
|
twinkle mtDNA helicase |
| chr7_+_34487833 | 0.80 |
ENSDART00000173854
|
cln6a
|
CLN6, transmembrane ER protein a |
| chr24_-_10021341 | 0.80 |
ENSDART00000137250
|
zgc:173856
|
zgc:173856 |
| chr9_+_18829360 | 0.78 |
ENSDART00000006514
|
gtf2f2b
|
general transcription factor IIF, polypeptide 2b |
| chr15_+_17345609 | 0.78 |
ENSDART00000111753
|
vmp1
|
vacuole membrane protein 1 |
| chr25_+_35891342 | 0.78 |
ENSDART00000147093
|
lsm14aa
|
LSM14A mRNA processing body assembly factor a |
| chr8_+_11425048 | 0.77 |
ENSDART00000018739
|
tjp2b
|
tight junction protein 2b (zona occludens 2) |
| chr15_-_11683529 | 0.77 |
ENSDART00000161445
|
fkrp
|
fukutin related protein |
| chr4_-_77125693 | 0.77 |
ENSDART00000174256
|
CU467646.3
|
|
| chr4_+_13586689 | 0.77 |
ENSDART00000067161
ENSDART00000138201 |
tnpo3
|
transportin 3 |
| chr20_+_29209926 | 0.76 |
ENSDART00000152949
ENSDART00000153016 |
katnbl1
|
katanin p80 subunit B-like 1 |
| chr11_+_44135351 | 0.76 |
ENSDART00000182914
|
FO704721.1
|
|
| chr1_-_23308225 | 0.75 |
ENSDART00000137567
ENSDART00000008201 |
smim14
|
small integral membrane protein 14 |
| chr10_-_13343831 | 0.75 |
ENSDART00000135941
|
il11ra
|
interleukin 11 receptor, alpha |
| chr23_-_20051369 | 0.74 |
ENSDART00000049836
|
bgnb
|
biglycan b |
| chr5_+_37903790 | 0.74 |
ENSDART00000162470
|
tmprss4b
|
transmembrane protease, serine 4b |
| chr11_+_18130300 | 0.73 |
ENSDART00000169146
|
zgc:175135
|
zgc:175135 |
| chr10_-_32494499 | 0.73 |
ENSDART00000129395
|
uvrag
|
UV radiation resistance associated gene |
| chr19_+_12406583 | 0.72 |
ENSDART00000013865
ENSDART00000151535 |
seh1l
|
SEH1-like (S. cerevisiae) |
| chr5_-_68333081 | 0.72 |
ENSDART00000168786
|
h1m
|
linker histone H1M |
| chr20_+_54304800 | 0.72 |
ENSDART00000121661
|
zp2.6
|
zona pellucida glycoprotein 2, tandem duplicate 6 |
| chr11_+_18157260 | 0.71 |
ENSDART00000144659
|
zgc:173545
|
zgc:173545 |
| chr24_-_25004553 | 0.71 |
ENSDART00000080997
ENSDART00000136860 |
zdhhc20b
|
zinc finger, DHHC-type containing 20b |
| chr25_-_6049339 | 0.71 |
ENSDART00000075184
|
snx1a
|
sorting nexin 1a |
| chr10_-_25217347 | 0.71 |
ENSDART00000036906
|
kpna7
|
karyopherin alpha 7 (importin alpha 8) |
| chr7_-_59165640 | 0.69 |
ENSDART00000170853
|
haus6
|
HAUS augmin-like complex, subunit 6 |
| chr8_+_45334255 | 0.69 |
ENSDART00000126848
ENSDART00000134161 ENSDART00000142322 ENSDART00000145011 ENSDART00000183560 |
pabpc1l
|
poly(A) binding protein, cytoplasmic 1-like |
| chr19_+_4968947 | 0.68 |
ENSDART00000003634
ENSDART00000134808 |
stard3
|
StAR-related lipid transfer (START) domain containing 3 |
| chr17_+_16429826 | 0.67 |
ENSDART00000136078
|
efcab11
|
EF-hand calcium binding domain 11 |
| chr17_+_25187226 | 0.67 |
ENSDART00000148431
|
cln8
|
CLN8, transmembrane ER and ERGIC protein |
| chr18_+_20560616 | 0.67 |
ENSDART00000136710
ENSDART00000151974 ENSDART00000121699 ENSDART00000040074 |
wee2
|
WEE1 homolog 2 (S. pombe) |
| chr3_+_56366395 | 0.67 |
ENSDART00000154367
|
cacng5b
|
calcium channel, voltage-dependent, gamma subunit 5b |
| chr8_-_19467011 | 0.66 |
ENSDART00000162010
|
zgc:92140
|
zgc:92140 |
| chr9_+_54695981 | 0.66 |
ENSDART00000183605
|
rab9a
|
RAB9A, member RAS oncogene family |
| chr14_-_33481428 | 0.66 |
ENSDART00000147059
ENSDART00000140001 ENSDART00000124242 ENSDART00000164836 ENSDART00000190104 ENSDART00000186833 ENSDART00000180873 |
lamp2
|
lysosomal-associated membrane protein 2 |
| chr8_+_11325310 | 0.65 |
ENSDART00000142577
|
fxn
|
frataxin |
| chr25_-_27621268 | 0.65 |
ENSDART00000146205
ENSDART00000073511 |
hyal6
|
hyaluronoglucosaminidase 6 |
| chr13_+_8693410 | 0.65 |
ENSDART00000138448
|
ttc7a
|
tetratricopeptide repeat domain 7A |
| chr19_-_5865766 | 0.64 |
ENSDART00000191007
|
LO018585.1
|
|
| chr3_-_26183699 | 0.63 |
ENSDART00000147517
ENSDART00000140731 |
si:ch211-11k18.4
|
si:ch211-11k18.4 |
| chr2_-_17115256 | 0.63 |
ENSDART00000190488
|
pif1
|
PIF1 5'-to-3' DNA helicase homolog (S. cerevisiae) |
| chr24_+_16547035 | 0.63 |
ENSDART00000164319
|
sema5a
|
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A |
| chr17_-_41798856 | 0.62 |
ENSDART00000156031
ENSDART00000192801 ENSDART00000180172 ENSDART00000084745 ENSDART00000175577 |
ralgapa2
|
Ral GTPase activating protein, alpha subunit 2 (catalytic) |
| chr23_-_32194397 | 0.62 |
ENSDART00000184206
ENSDART00000166682 |
nr4a1
|
nuclear receptor subfamily 4, group A, member 1 |
| chr6_-_40922971 | 0.62 |
ENSDART00000155363
|
sfi1
|
SFI1 centrin binding protein |
| chr18_+_44849809 | 0.62 |
ENSDART00000097328
|
arfgap2
|
ADP-ribosylation factor GTPase activating protein 2 |
| chr19_+_15521997 | 0.61 |
ENSDART00000003164
|
ppp1r8a
|
protein phosphatase 1, regulatory subunit 8a |
| chr11_-_35171768 | 0.61 |
ENSDART00000192896
|
traip
|
TRAF-interacting protein |
| chr7_-_26270014 | 0.60 |
ENSDART00000079347
|
serpine1
|
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 |
| chr1_-_54972170 | 0.60 |
ENSDART00000150548
ENSDART00000038330 |
khsrp
|
KH-type splicing regulatory protein |
| chr5_-_67241633 | 0.59 |
ENSDART00000114783
|
clip1a
|
CAP-GLY domain containing linker protein 1a |
| chr19_-_18313303 | 0.59 |
ENSDART00000164644
ENSDART00000167480 ENSDART00000163104 |
si:dkey-208k4.2
|
si:dkey-208k4.2 |
| chr19_-_5805923 | 0.59 |
ENSDART00000134340
|
si:ch211-264f5.8
|
si:ch211-264f5.8 |
| chr25_-_4713461 | 0.59 |
ENSDART00000155302
|
drd4a
|
dopamine receptor D4a |
| chr16_-_41714988 | 0.59 |
ENSDART00000138798
|
cep85
|
centrosomal protein 85 |
| chr7_+_59033902 | 0.58 |
ENSDART00000168888
|
fastkd3
|
FAST kinase domains 3 |
| chr18_-_20458840 | 0.58 |
ENSDART00000177125
|
kif23
|
kinesin family member 23 |
| chr15_-_9272328 | 0.58 |
ENSDART00000172114
|
calm2a
|
calmodulin 2a (phosphorylase kinase, delta) |
| chr1_+_35985813 | 0.58 |
ENSDART00000179634
ENSDART00000139636 ENSDART00000175902 |
zgc:152968
|
zgc:152968 |
| chr23_-_14766902 | 0.57 |
ENSDART00000168113
|
gss
|
glutathione synthetase |
| chr17_+_8799451 | 0.57 |
ENSDART00000189814
ENSDART00000191577 |
tonsl
|
tonsoku-like, DNA repair protein |
| chr16_+_39159752 | 0.57 |
ENSDART00000122081
|
sybu
|
syntabulin (syntaxin-interacting) |
| chr1_+_49266886 | 0.56 |
ENSDART00000137179
|
caly
|
calcyon neuron-specific vesicular protein |
| chr8_-_21142550 | 0.56 |
ENSDART00000143192
ENSDART00000186820 ENSDART00000135938 |
cpt2
|
carnitine palmitoyltransferase 2 |
| chr23_+_27782071 | 0.55 |
ENSDART00000131379
|
kmt2d
|
lysine (K)-specific methyltransferase 2D |
| chr5_-_19006290 | 0.55 |
ENSDART00000137022
|
golga3
|
golgin A3 |
| chr13_-_35808904 | 0.55 |
ENSDART00000171667
|
map3k4
|
mitogen-activated protein kinase kinase kinase 4 |
| chr8_-_49728590 | 0.55 |
ENSDART00000135714
ENSDART00000138810 ENSDART00000098319 |
gkap1
|
G kinase anchoring protein 1 |
| chr23_+_42254960 | 0.54 |
ENSDART00000102980
|
zcchc11
|
zinc finger, CCHC domain containing 11 |
| chr12_+_22674030 | 0.54 |
ENSDART00000153254
ENSDART00000152930 |
cdca9
|
cell division cycle associated 9 |
| chr10_-_32494304 | 0.54 |
ENSDART00000028161
|
uvrag
|
UV radiation resistance associated gene |
| chr23_-_2901167 | 0.54 |
ENSDART00000165955
ENSDART00000190616 |
zhx3
|
zinc fingers and homeoboxes 3 |
| chr12_-_18577983 | 0.54 |
ENSDART00000193262
|
zdhhc4
|
zinc finger, DHHC-type containing 4 |
| chr25_+_36292057 | 0.54 |
ENSDART00000152329
|
bmb
|
brambleberry |
| chr24_-_31904924 | 0.54 |
ENSDART00000156060
ENSDART00000129741 ENSDART00000154276 |
si:ch73-78o10.1
|
si:ch73-78o10.1 |
| chr5_-_68093169 | 0.53 |
ENSDART00000051849
|
slc25a11
|
solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11 |
| chr20_-_51831657 | 0.53 |
ENSDART00000165076
|
mia3
|
melanoma inhibitory activity family, member 3 |
| chr20_-_51831816 | 0.53 |
ENSDART00000060505
|
mia3
|
melanoma inhibitory activity family, member 3 |
| chr17_-_21162821 | 0.52 |
ENSDART00000157283
|
abhd12
|
abhydrolase domain containing 12 |
| chr14_+_32942063 | 0.52 |
ENSDART00000187705
|
lnx2b
|
ligand of numb-protein X 2b |
| chr13_-_8692860 | 0.52 |
ENSDART00000058107
|
mcfd2
|
multiple coagulation factor deficiency 2 |
| chr25_-_12410198 | 0.51 |
ENSDART00000182281
|
det1
|
DET1, COP1 ubiquitin ligase partner |
| chr4_+_25917915 | 0.50 |
ENSDART00000138603
|
vezt
|
vezatin, adherens junctions transmembrane protein |
| chr18_+_50880096 | 0.50 |
ENSDART00000169782
|
si:ch1073-450f2.1
|
si:ch1073-450f2.1 |
| chr17_+_49500820 | 0.50 |
ENSDART00000170306
|
AREL1
|
apoptosis resistant E3 ubiquitin protein ligase 1 |
| chr9_-_21460164 | 0.49 |
ENSDART00000133469
|
zmym2
|
zinc finger, MYM-type 2 |
| chr20_-_40758410 | 0.49 |
ENSDART00000183031
|
cx34.5
|
connexin 34.5 |
| chr15_-_25367309 | 0.49 |
ENSDART00000047471
|
cluha
|
clustered mitochondria (cluA/CLU1) homolog a |
| chr23_+_33963619 | 0.48 |
ENSDART00000140666
ENSDART00000084792 |
plpbp
|
pyridoxal phosphate binding protein |
| chr11_+_18873619 | 0.48 |
ENSDART00000176141
|
magi1b
|
membrane associated guanylate kinase, WW and PDZ domain containing 1b |
| chr12_-_4408828 | 0.48 |
ENSDART00000152447
|
si:ch211-173d10.1
|
si:ch211-173d10.1 |
| chr20_+_28803977 | 0.47 |
ENSDART00000153351
ENSDART00000038149 |
fntb
|
farnesyltransferase, CAAX box, beta |
| chr10_+_43039947 | 0.47 |
ENSDART00000193434
|
atg10
|
ATG10 autophagy related 10 homolog (S. cerevisiae) |
| chr19_-_12212692 | 0.47 |
ENSDART00000142077
ENSDART00000151599 ENSDART00000140834 ENSDART00000078781 |
znf706
|
zinc finger protein 706 |
| chr4_+_4849789 | 0.47 |
ENSDART00000130818
ENSDART00000127751 |
ptprz1b
|
protein tyrosine phosphatase, receptor-type, Z polypeptide 1b |
| chr25_+_2361721 | 0.47 |
ENSDART00000172905
|
zmp:0000000932
|
zmp:0000000932 |
| chr5_-_9625459 | 0.47 |
ENSDART00000143347
|
sh2b3
|
SH2B adaptor protein 3 |
| chr19_-_20430892 | 0.47 |
ENSDART00000111409
|
tbc1d5
|
TBC1 domain family, member 5 |
| chr15_+_46313082 | 0.46 |
ENSDART00000153830
|
si:ch1073-190k2.1
|
si:ch1073-190k2.1 |
| chr24_-_25144441 | 0.46 |
ENSDART00000152104
|
phldb2b
|
pleckstrin homology-like domain, family B, member 2b |
| chr3_+_32832538 | 0.46 |
ENSDART00000139410
|
cd2bp2
|
CD2 (cytoplasmic tail) binding protein 2 |
| chr24_+_39518774 | 0.46 |
ENSDART00000132939
|
dcun1d3
|
defective in cullin neddylation 1 domain containing 3 |
| chr3_-_32337653 | 0.46 |
ENSDART00000156918
ENSDART00000156551 |
si:dkey-16p21.8
|
si:dkey-16p21.8 |
| chr9_-_38021889 | 0.46 |
ENSDART00000183482
ENSDART00000124333 |
adcy5
|
adenylate cyclase 5 |
| chr17_+_24821627 | 0.46 |
ENSDART00000112389
|
wdr43
|
WD repeat domain 43 |
Network of associatons between targets according to the STRING database.
First level regulatory network of en1b_en2a+en2b_gbx1_emx1
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.4 | 6.9 | GO:0016338 | calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338) |
| 1.0 | 4.0 | GO:0030718 | germ-line stem cell population maintenance(GO:0030718) |
| 0.6 | 1.7 | GO:0039015 | spinal cord anterior/posterior patterning(GO:0021512) cell proliferation involved in pronephros development(GO:0039015) cell proliferation involved in kidney development(GO:0072111) |
| 0.4 | 1.1 | GO:0000212 | meiotic spindle organization(GO:0000212) |
| 0.3 | 0.9 | GO:0048200 | COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205) |
| 0.3 | 1.2 | GO:0035124 | embryonic caudal fin morphogenesis(GO:0035124) |
| 0.3 | 1.4 | GO:0006978 | DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978) DNA damage response, signal transduction resulting in transcription(GO:0042772) |
| 0.3 | 4.7 | GO:0007339 | binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344) |
| 0.3 | 1.0 | GO:0060283 | negative regulation of oocyte development(GO:0060283) |
| 0.3 | 1.0 | GO:0060074 | synapse maturation(GO:0060074) |
| 0.3 | 2.0 | GO:0033206 | meiotic cytokinesis(GO:0033206) polar body extrusion after meiotic divisions(GO:0040038) |
| 0.2 | 2.0 | GO:0046247 | carotene metabolic process(GO:0016119) carotene catabolic process(GO:0016121) terpene metabolic process(GO:0042214) terpene catabolic process(GO:0046247) |
| 0.2 | 2.0 | GO:0050957 | equilibrioception(GO:0050957) |
| 0.2 | 0.7 | GO:0060631 | regulation of meiosis I(GO:0060631) |
| 0.2 | 1.3 | GO:1902975 | cell cycle DNA replication initiation(GO:1902292) nuclear cell cycle DNA replication initiation(GO:1902315) mitotic DNA replication initiation(GO:1902975) |
| 0.2 | 0.9 | GO:0090646 | mitochondrial tRNA processing(GO:0090646) |
| 0.2 | 3.0 | GO:0043562 | cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562) |
| 0.2 | 0.8 | GO:0060049 | regulation of protein glycosylation(GO:0060049) |
| 0.1 | 1.2 | GO:2000290 | smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021910) regulation of myotome development(GO:2000290) |
| 0.1 | 0.9 | GO:0017187 | peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214) |
| 0.1 | 0.6 | GO:0006750 | glutathione biosynthetic process(GO:0006750) |
| 0.1 | 0.4 | GO:1903003 | positive regulation of protein deubiquitination(GO:1903003) |
| 0.1 | 1.1 | GO:2001286 | caveolin-mediated endocytosis(GO:0072584) negative regulation of clathrin-mediated endocytosis(GO:1900186) regulation of caveolin-mediated endocytosis(GO:2001286) negative regulation of caveolin-mediated endocytosis(GO:2001287) |
| 0.1 | 1.7 | GO:0045842 | positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101) |
| 0.1 | 0.5 | GO:0036306 | embryonic heart tube elongation(GO:0036306) |
| 0.1 | 0.4 | GO:0061037 | negative regulation of chondrocyte differentiation(GO:0032331) negative regulation of cartilage development(GO:0061037) negative regulation of chondrocyte development(GO:0061182) regulation of bone mineralization involved in bone maturation(GO:1900157) negative regulation of bone mineralization involved in bone maturation(GO:1900158) negative regulation of bone development(GO:1903011) |
| 0.1 | 0.5 | GO:0018343 | protein farnesylation(GO:0018343) |
| 0.1 | 0.7 | GO:0034498 | early endosome to Golgi transport(GO:0034498) |
| 0.1 | 0.4 | GO:0045040 | outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040) |
| 0.1 | 0.3 | GO:1903644 | regulation of protein folding(GO:1903332) positive regulation of protein folding(GO:1903334) regulation of chaperone-mediated protein folding(GO:1903644) positive regulation of chaperone-mediated protein folding(GO:1903646) |
| 0.1 | 1.6 | GO:0045740 | positive regulation of DNA replication(GO:0045740) |
| 0.1 | 1.0 | GO:0006465 | signal peptide processing(GO:0006465) |
| 0.1 | 1.3 | GO:0000002 | mitochondrial genome maintenance(GO:0000002) |
| 0.1 | 0.5 | GO:0007344 | karyogamy(GO:0000741) pronuclear fusion(GO:0007344) |
| 0.1 | 0.5 | GO:0015709 | thiosulfate transport(GO:0015709) oxaloacetate transport(GO:0015729) malate transport(GO:0015743) succinate transport(GO:0015744) succinate transmembrane transport(GO:0071422) malate transmembrane transport(GO:0071423) |
| 0.1 | 0.4 | GO:0042796 | snRNA transcription from RNA polymerase III promoter(GO:0042796) |
| 0.1 | 0.5 | GO:1901910 | diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911) |
| 0.1 | 0.5 | GO:0052651 | phosphatidylserine catabolic process(GO:0006660) monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651) |
| 0.1 | 0.3 | GO:0030043 | actin filament fragmentation(GO:0030043) |
| 0.1 | 0.6 | GO:0031116 | positive regulation of microtubule polymerization(GO:0031116) |
| 0.1 | 0.9 | GO:0015740 | C4-dicarboxylate transport(GO:0015740) acidic amino acid transport(GO:0015800) aspartate transport(GO:0015810) L-glutamate transport(GO:0015813) malate-aspartate shuttle(GO:0043490) |
| 0.1 | 0.3 | GO:0001562 | response to protozoan(GO:0001562) defense response to protozoan(GO:0042832) |
| 0.1 | 0.5 | GO:0018410 | C-terminal protein amino acid modification(GO:0018410) |
| 0.1 | 0.4 | GO:0042182 | ketone catabolic process(GO:0042182) |
| 0.1 | 2.5 | GO:0035469 | determination of pancreatic left/right asymmetry(GO:0035469) |
| 0.1 | 0.7 | GO:0044528 | regulation of mitochondrial mRNA stability(GO:0044528) |
| 0.1 | 1.3 | GO:0035493 | SNARE complex assembly(GO:0035493) |
| 0.1 | 0.4 | GO:0048209 | regulation of vesicle targeting, to, from or within Golgi(GO:0048209) |
| 0.1 | 0.3 | GO:0000350 | generation of catalytic spliceosome for second transesterification step(GO:0000350) |
| 0.1 | 0.6 | GO:0036089 | cleavage furrow formation(GO:0036089) embryonic cleavage(GO:0040016) |
| 0.1 | 0.4 | GO:0032776 | DNA methylation on cytosine(GO:0032776) |
| 0.1 | 0.7 | GO:0051315 | attachment of mitotic spindle microtubules to kinetochore(GO:0051315) |
| 0.1 | 0.2 | GO:0043553 | negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553) negative regulation of lipid kinase activity(GO:0090219) |
| 0.1 | 0.2 | GO:0071918 | urea transmembrane transport(GO:0071918) |
| 0.1 | 0.4 | GO:0043137 | DNA replication, removal of RNA primer(GO:0043137) |
| 0.1 | 0.3 | GO:0033540 | fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540) |
| 0.1 | 0.2 | GO:0070129 | regulation of mitochondrial translation(GO:0070129) positive regulation of mitochondrial translation(GO:0070131) |
| 0.1 | 0.8 | GO:0042953 | lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872) |
| 0.1 | 0.8 | GO:1903318 | negative regulation of protein processing(GO:0010955) negative regulation of protein maturation(GO:1903318) |
| 0.1 | 0.2 | GO:0002926 | tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridine biosynthesis.(GO:0002926) |
| 0.1 | 0.5 | GO:0045901 | positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905) |
| 0.1 | 0.2 | GO:0015760 | hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760) |
| 0.1 | 1.5 | GO:0050796 | regulation of insulin secretion(GO:0050796) |
| 0.1 | 0.3 | GO:0071596 | ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596) |
| 0.1 | 2.3 | GO:0018231 | peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231) |
| 0.1 | 0.6 | GO:0003428 | growth plate cartilage morphogenesis(GO:0003422) chondrocyte intercalation involved in growth plate cartilage morphogenesis(GO:0003428) |
| 0.1 | 1.0 | GO:0015693 | magnesium ion transport(GO:0015693) |
| 0.1 | 0.2 | GO:0046951 | ketone body biosynthetic process(GO:0046951) |
| 0.1 | 0.7 | GO:0006622 | protein targeting to lysosome(GO:0006622) |
| 0.1 | 0.1 | GO:0045191 | regulation of isotype switching(GO:0045191) positive regulation of isotype switching(GO:0045830) |
| 0.1 | 0.7 | GO:0006607 | NLS-bearing protein import into nucleus(GO:0006607) |
| 0.1 | 1.0 | GO:0019433 | triglyceride catabolic process(GO:0019433) |
| 0.1 | 1.1 | GO:0035459 | cargo loading into vesicle(GO:0035459) |
| 0.1 | 2.2 | GO:0060968 | regulation of gene silencing(GO:0060968) |
| 0.1 | 0.2 | GO:0051645 | Golgi localization(GO:0051645) |
| 0.1 | 0.5 | GO:0043435 | response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376) |
| 0.1 | 0.2 | GO:0099563 | modification of synaptic structure(GO:0099563) |
| 0.1 | 0.3 | GO:0019254 | carnitine metabolic process, CoA-linked(GO:0019254) |
| 0.1 | 0.2 | GO:0006297 | nucleotide-excision repair, DNA gap filling(GO:0006297) |
| 0.1 | 1.1 | GO:0031297 | replication fork processing(GO:0031297) |
| 0.1 | 2.5 | GO:0000038 | very long-chain fatty acid metabolic process(GO:0000038) |
| 0.1 | 0.6 | GO:0021521 | ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573) |
| 0.1 | 0.3 | GO:0000012 | single strand break repair(GO:0000012) |
| 0.1 | 0.3 | GO:0010866 | regulation of triglyceride biosynthetic process(GO:0010866) positive regulation of triglyceride biosynthetic process(GO:0010867) positive regulation of triglyceride metabolic process(GO:0090208) |
| 0.0 | 0.6 | GO:0009303 | rRNA transcription(GO:0009303) swim bladder maturation(GO:0048796) swim bladder inflation(GO:0048798) |
| 0.0 | 0.3 | GO:0032185 | septin ring organization(GO:0031106) septin cytoskeleton organization(GO:0032185) |
| 0.0 | 0.8 | GO:0030259 | lipid glycosylation(GO:0030259) |
| 0.0 | 0.1 | GO:0046125 | deoxyribonucleoside metabolic process(GO:0009120) thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125) |
| 0.0 | 1.2 | GO:0032008 | positive regulation of TOR signaling(GO:0032008) |
| 0.0 | 1.4 | GO:0006635 | fatty acid beta-oxidation(GO:0006635) |
| 0.0 | 1.3 | GO:0051014 | actin filament severing(GO:0051014) |
| 0.0 | 0.6 | GO:0030214 | hyaluronan catabolic process(GO:0030214) |
| 0.0 | 5.0 | GO:0017148 | negative regulation of translation(GO:0017148) |
| 0.0 | 1.0 | GO:0033138 | positive regulation of peptidyl-serine phosphorylation(GO:0033138) |
| 0.0 | 0.2 | GO:0043152 | induction of bacterial agglutination(GO:0043152) |
| 0.0 | 0.3 | GO:0045604 | regulation of epidermal cell differentiation(GO:0045604) |
| 0.0 | 0.3 | GO:0060282 | positive regulation of oocyte development(GO:0060282) |
| 0.0 | 0.4 | GO:0006177 | GMP biosynthetic process(GO:0006177) GMP metabolic process(GO:0046037) |
| 0.0 | 0.3 | GO:0006787 | porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149) |
| 0.0 | 0.8 | GO:0048026 | positive regulation of mRNA splicing, via spliceosome(GO:0048026) |
| 0.0 | 0.7 | GO:0098943 | neurotransmitter receptor transport, postsynaptic endosome to lysosome(GO:0098943) |
| 0.0 | 0.2 | GO:0000395 | mRNA 5'-splice site recognition(GO:0000395) |
| 0.0 | 0.2 | GO:0044209 | AMP salvage(GO:0044209) |
| 0.0 | 0.5 | GO:0048312 | intracellular distribution of mitochondria(GO:0048312) |
| 0.0 | 0.1 | GO:0019323 | pentose catabolic process(GO:0019323) |
| 0.0 | 3.1 | GO:0008203 | cholesterol metabolic process(GO:0008203) |
| 0.0 | 1.2 | GO:0006506 | GPI anchor biosynthetic process(GO:0006506) |
| 0.0 | 0.3 | GO:0033314 | mitotic DNA replication checkpoint(GO:0033314) |
| 0.0 | 0.2 | GO:0055107 | Golgi to secretory granule transport(GO:0055107) |
| 0.0 | 0.3 | GO:2000650 | negative regulation of sodium ion transmembrane transporter activity(GO:2000650) |
| 0.0 | 0.3 | GO:0070979 | protein K11-linked ubiquitination(GO:0070979) |
| 0.0 | 0.2 | GO:0097355 | protein localization to heterochromatin(GO:0097355) |
| 0.0 | 0.3 | GO:0061635 | regulation of protein complex stability(GO:0061635) |
| 0.0 | 0.3 | GO:0032958 | inositol phosphate biosynthetic process(GO:0032958) |
| 0.0 | 0.5 | GO:0051443 | protein neddylation(GO:0045116) positive regulation of ubiquitin-protein transferase activity(GO:0051443) |
| 0.0 | 0.2 | GO:0048755 | branching morphogenesis of a nerve(GO:0048755) |
| 0.0 | 0.4 | GO:0006363 | termination of RNA polymerase I transcription(GO:0006363) |
| 0.0 | 0.1 | GO:0045002 | double-strand break repair via single-strand annealing(GO:0045002) |
| 0.0 | 0.2 | GO:0031571 | mitotic G1 DNA damage checkpoint(GO:0031571) |
| 0.0 | 0.8 | GO:0090557 | establishment of endothelial intestinal barrier(GO:0090557) |
| 0.0 | 0.7 | GO:0031163 | iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163) |
| 0.0 | 0.3 | GO:0044030 | regulation of DNA methylation(GO:0044030) |
| 0.0 | 1.8 | GO:0046856 | phosphatidylinositol dephosphorylation(GO:0046856) |
| 0.0 | 0.7 | GO:0030301 | cholesterol transport(GO:0030301) |
| 0.0 | 0.3 | GO:2000369 | regulation of clathrin-mediated endocytosis(GO:2000369) |
| 0.0 | 0.2 | GO:0008211 | glucocorticoid metabolic process(GO:0008211) |
| 0.0 | 0.2 | GO:0016322 | neuron remodeling(GO:0016322) |
| 0.0 | 0.2 | GO:0017006 | protein-heme linkage(GO:0017003) protein-tetrapyrrole linkage(GO:0017006) cytochrome c-heme linkage(GO:0018063) |
| 0.0 | 0.3 | GO:1902038 | positive regulation of hematopoietic stem cell differentiation(GO:1902038) |
| 0.0 | 0.5 | GO:0045471 | response to ethanol(GO:0045471) |
| 0.0 | 0.2 | GO:0071684 | hatching(GO:0035188) organism emergence from protective structure(GO:0071684) |
| 0.0 | 0.3 | GO:0071816 | tail-anchored membrane protein insertion into ER membrane(GO:0071816) |
| 0.0 | 0.3 | GO:0021520 | spinal cord motor neuron cell fate specification(GO:0021520) |
| 0.0 | 0.3 | GO:0007172 | signal complex assembly(GO:0007172) |
| 0.0 | 0.3 | GO:0007023 | post-chaperonin tubulin folding pathway(GO:0007023) |
| 0.0 | 0.8 | GO:0080171 | lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171) |
| 0.0 | 0.2 | GO:0097010 | eukaryotic translation initiation factor 4F complex assembly(GO:0097010) |
| 0.0 | 0.1 | GO:0048211 | Golgi vesicle docking(GO:0048211) |
| 0.0 | 0.3 | GO:0035677 | posterior lateral line neuromast hair cell development(GO:0035677) |
| 0.0 | 0.1 | GO:1902946 | protein localization to early endosome(GO:1902946) |
| 0.0 | 0.1 | GO:0045721 | negative regulation of gluconeogenesis(GO:0045721) |
| 0.0 | 0.7 | GO:0032482 | Rab protein signal transduction(GO:0032482) |
| 0.0 | 0.2 | GO:0070301 | cellular response to hydrogen peroxide(GO:0070301) |
| 0.0 | 0.5 | GO:0016925 | protein sumoylation(GO:0016925) |
| 0.0 | 0.3 | GO:0035336 | long-chain fatty-acyl-CoA metabolic process(GO:0035336) |
| 0.0 | 0.1 | GO:1902766 | skeletal muscle satellite cell migration(GO:1902766) |
| 0.0 | 0.6 | GO:0035308 | negative regulation of dephosphorylation(GO:0035305) negative regulation of protein dephosphorylation(GO:0035308) |
| 0.0 | 0.9 | GO:0007050 | cell cycle arrest(GO:0007050) |
| 0.0 | 0.1 | GO:0051818 | killing of cells of other organism(GO:0031640) disruption of cells of other organism(GO:0044364) disruption of cells of other organism involved in symbiotic interaction(GO:0051818) killing of cells in other organism involved in symbiotic interaction(GO:0051883) |
| 0.0 | 0.2 | GO:0000055 | ribosomal large subunit export from nucleus(GO:0000055) |
| 0.0 | 0.2 | GO:0035871 | protein K11-linked deubiquitination(GO:0035871) |
| 0.0 | 0.1 | GO:0042364 | water-soluble vitamin biosynthetic process(GO:0042364) |
| 0.0 | 1.0 | GO:0015914 | phospholipid transport(GO:0015914) |
| 0.0 | 0.9 | GO:0055088 | lipid homeostasis(GO:0055088) |
| 0.0 | 0.1 | GO:0006895 | Golgi to endosome transport(GO:0006895) |
| 0.0 | 0.5 | GO:0006919 | activation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0006919) |
| 0.0 | 1.4 | GO:0046854 | phosphatidylinositol phosphorylation(GO:0046854) |
| 0.0 | 0.5 | GO:0048268 | clathrin coat assembly(GO:0048268) |
| 0.0 | 0.1 | GO:0097101 | blood vessel endothelial cell fate specification(GO:0097101) |
| 0.0 | 0.4 | GO:0007004 | RNA-dependent DNA biosynthetic process(GO:0006278) telomere maintenance via telomerase(GO:0007004) |
| 0.0 | 0.8 | GO:0006367 | transcription initiation from RNA polymerase II promoter(GO:0006367) |
| 0.0 | 0.2 | GO:0038007 | netrin-activated signaling pathway(GO:0038007) |
| 0.0 | 1.0 | GO:0044744 | protein import into nucleus(GO:0006606) protein targeting to nucleus(GO:0044744) single-organism nuclear import(GO:1902593) |
| 0.0 | 0.2 | GO:0099638 | neurotransmitter receptor transport, endosome to postsynaptic membrane(GO:0098887) endosome to plasma membrane protein transport(GO:0099638) neurotransmitter receptor transport, endosome to plasma membrane(GO:0099639) |
| 0.0 | 0.1 | GO:0009312 | oligosaccharide biosynthetic process(GO:0009312) |
| 0.0 | 0.5 | GO:0070936 | protein K48-linked ubiquitination(GO:0070936) |
| 0.0 | 0.1 | GO:2000479 | regulation of cAMP-dependent protein kinase activity(GO:2000479) |
| 0.0 | 0.1 | GO:0050911 | detection of chemical stimulus involved in sensory perception of smell(GO:0050911) |
| 0.0 | 0.1 | GO:0061668 | mitochondrial ribosome assembly(GO:0061668) |
| 0.0 | 0.1 | GO:0006686 | sphingomyelin biosynthetic process(GO:0006686) |
| 0.0 | 0.2 | GO:0038203 | TORC2 signaling(GO:0038203) |
| 0.0 | 0.5 | GO:0006497 | protein lipidation(GO:0006497) lipoprotein biosynthetic process(GO:0042158) |
| 0.0 | 0.1 | GO:0051877 | pigment granule aggregation in cell center(GO:0051877) |
| 0.0 | 0.3 | GO:0034198 | cellular response to amino acid starvation(GO:0034198) |
| 0.0 | 0.2 | GO:0008089 | anterograde axonal transport(GO:0008089) |
| 0.0 | 0.1 | GO:0036268 | swimming(GO:0036268) |
| 0.0 | 0.1 | GO:0046070 | dGTP catabolic process(GO:0006203) purine nucleoside triphosphate catabolic process(GO:0009146) purine deoxyribonucleoside triphosphate catabolic process(GO:0009217) dGTP metabolic process(GO:0046070) |
| 0.0 | 1.0 | GO:0015718 | monocarboxylic acid transport(GO:0015718) |
| 0.0 | 0.1 | GO:0031061 | negative regulation of histone methylation(GO:0031061) |
| 0.0 | 0.1 | GO:0006777 | Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189) |
| 0.0 | 0.5 | GO:0032436 | positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436) positive regulation of proteasomal protein catabolic process(GO:1901800) |
| 0.0 | 0.1 | GO:0019375 | galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375) |
| 0.0 | 0.1 | GO:0002551 | mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531) |
| 0.0 | 0.2 | GO:0006044 | N-acetylglucosamine metabolic process(GO:0006044) |
| 0.0 | 0.4 | GO:0000266 | mitochondrial fission(GO:0000266) |
| 0.0 | 0.2 | GO:0016486 | peptide hormone processing(GO:0016486) |
| 0.0 | 0.1 | GO:0060061 | Spemann organizer formation(GO:0060061) |
| 0.0 | 0.2 | GO:2000401 | regulation of lymphocyte migration(GO:2000401) |
| 0.0 | 0.1 | GO:0045670 | regulation of osteoclast differentiation(GO:0045670) |
| 0.0 | 0.1 | GO:0021877 | forebrain neuron fate commitment(GO:0021877) |
| 0.0 | 0.2 | GO:0006614 | SRP-dependent cotranslational protein targeting to membrane(GO:0006614) |
| 0.0 | 0.3 | GO:0060021 | palate development(GO:0060021) |
| 0.0 | 0.3 | GO:0070593 | dendrite self-avoidance(GO:0070593) |
| 0.0 | 0.2 | GO:0043524 | negative regulation of neuron apoptotic process(GO:0043524) |
| 0.0 | 1.0 | GO:0009615 | response to virus(GO:0009615) |
| 0.0 | 0.2 | GO:0070989 | oxidative demethylation(GO:0070989) |
| 0.0 | 0.3 | GO:0071427 | mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427) |
| 0.0 | 0.3 | GO:0009214 | cyclic nucleotide catabolic process(GO:0009214) |
| 0.0 | 0.3 | GO:0038061 | NIK/NF-kappaB signaling(GO:0038061) |
| 0.0 | 0.5 | GO:0035335 | peptidyl-tyrosine dephosphorylation(GO:0035335) |
| 0.0 | 0.2 | GO:0018216 | peptidyl-arginine methylation(GO:0018216) |
| 0.0 | 0.3 | GO:0006641 | triglyceride metabolic process(GO:0006641) |
| 0.0 | 0.1 | GO:0006102 | isocitrate metabolic process(GO:0006102) |
| 0.0 | 0.1 | GO:0031060 | regulation of histone methylation(GO:0031060) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.6 | 1.7 | GO:0097189 | apoptotic body(GO:0097189) |
| 0.3 | 3.8 | GO:0034361 | very-low-density lipoprotein particle(GO:0034361) |
| 0.3 | 1.0 | GO:0071458 | integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553) |
| 0.2 | 1.2 | GO:0070724 | BMP receptor complex(GO:0070724) |
| 0.2 | 0.7 | GO:0031310 | integral component of vacuolar membrane(GO:0031166) intrinsic component of vacuolar membrane(GO:0031310) |
| 0.2 | 0.7 | GO:1990498 | mitotic spindle microtubule(GO:1990498) |
| 0.1 | 0.8 | GO:0000506 | glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506) |
| 0.1 | 1.0 | GO:0005662 | DNA replication factor A complex(GO:0005662) |
| 0.1 | 1.4 | GO:0016602 | CCAAT-binding factor complex(GO:0016602) |
| 0.1 | 0.4 | GO:0019185 | snRNA-activating protein complex(GO:0019185) |
| 0.1 | 0.5 | GO:0005965 | protein farnesyltransferase complex(GO:0005965) |
| 0.1 | 0.3 | GO:0072380 | TRC complex(GO:0072380) |
| 0.1 | 1.1 | GO:0045171 | intercellular bridge(GO:0045171) |
| 0.1 | 0.9 | GO:0009295 | nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645) |
| 0.1 | 0.8 | GO:0005674 | transcription factor TFIIF complex(GO:0005674) |
| 0.1 | 1.8 | GO:0005682 | U5 snRNP(GO:0005682) |
| 0.1 | 0.4 | GO:0032299 | ribonuclease H2 complex(GO:0032299) |
| 0.1 | 0.5 | GO:0032133 | chromosome passenger complex(GO:0032133) |
| 0.1 | 0.7 | GO:0044232 | organelle membrane contact site(GO:0044232) |
| 0.1 | 0.4 | GO:0005797 | Golgi medial cisterna(GO:0005797) |
| 0.1 | 2.9 | GO:0000421 | autophagosome membrane(GO:0000421) |
| 0.1 | 1.3 | GO:0042555 | MCM complex(GO:0042555) |
| 0.1 | 0.7 | GO:0030670 | phagocytic vesicle membrane(GO:0030670) |
| 0.1 | 0.3 | GO:0070209 | ASTRA complex(GO:0070209) |
| 0.1 | 0.7 | GO:0031080 | nuclear pore outer ring(GO:0031080) |
| 0.1 | 1.5 | GO:0030667 | secretory granule membrane(GO:0030667) |
| 0.1 | 0.7 | GO:0030904 | retromer complex(GO:0030904) |
| 0.1 | 1.7 | GO:0005680 | anaphase-promoting complex(GO:0005680) |
| 0.1 | 0.5 | GO:0070938 | contractile ring(GO:0070938) |
| 0.1 | 0.3 | GO:0033165 | interphotoreceptor matrix(GO:0033165) |
| 0.1 | 6.7 | GO:0005923 | bicellular tight junction(GO:0005923) occluding junction(GO:0070160) |
| 0.1 | 0.8 | GO:1990124 | messenger ribonucleoprotein complex(GO:1990124) |
| 0.1 | 0.3 | GO:0071595 | Nem1-Spo7 phosphatase complex(GO:0071595) |
| 0.0 | 0.4 | GO:0005671 | Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671) |
| 0.0 | 0.2 | GO:0043625 | delta DNA polymerase complex(GO:0043625) |
| 0.0 | 0.4 | GO:0001401 | mitochondrial sorting and assembly machinery complex(GO:0001401) |
| 0.0 | 1.1 | GO:0070971 | endoplasmic reticulum exit site(GO:0070971) |
| 0.0 | 1.0 | GO:0005881 | cytoplasmic microtubule(GO:0005881) |
| 0.0 | 0.3 | GO:0072379 | BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379) |
| 0.0 | 1.1 | GO:0005876 | spindle microtubule(GO:0005876) |
| 0.0 | 0.3 | GO:0035060 | brahma complex(GO:0035060) |
| 0.0 | 0.8 | GO:0033116 | endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116) |
| 0.0 | 0.3 | GO:0032021 | NELF complex(GO:0032021) |
| 0.0 | 0.6 | GO:0031312 | extrinsic component of organelle membrane(GO:0031312) |
| 0.0 | 0.6 | GO:0044666 | MLL3/4 complex(GO:0044666) |
| 0.0 | 0.1 | GO:1990131 | EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131) |
| 0.0 | 0.1 | GO:0044279 | other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217) other organism cell membrane(GO:0044218) other organism membrane(GO:0044279) |
| 0.0 | 0.1 | GO:0034657 | GID complex(GO:0034657) |
| 0.0 | 0.6 | GO:0045180 | basal cortex(GO:0045180) |
| 0.0 | 0.9 | GO:0043186 | P granule(GO:0043186) |
| 0.0 | 0.2 | GO:0043083 | synaptic cleft(GO:0043083) |
| 0.0 | 0.2 | GO:0005786 | signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500) |
| 0.0 | 0.1 | GO:1902636 | kinociliary basal body(GO:1902636) |
| 0.0 | 2.6 | GO:0005882 | intermediate filament(GO:0005882) |
| 0.0 | 0.4 | GO:0030057 | desmosome(GO:0030057) |
| 0.0 | 0.1 | GO:0019008 | molybdopterin synthase complex(GO:0019008) |
| 0.0 | 0.4 | GO:0035371 | microtubule plus-end(GO:0035371) |
| 0.0 | 0.2 | GO:0033588 | Elongator holoenzyme complex(GO:0033588) |
| 0.0 | 0.1 | GO:1990513 | CLOCK-BMAL transcription complex(GO:1990513) |
| 0.0 | 0.2 | GO:0030126 | COPI vesicle coat(GO:0030126) |
| 0.0 | 0.8 | GO:0005657 | replication fork(GO:0005657) |
| 0.0 | 0.2 | GO:0000974 | Prp19 complex(GO:0000974) |
| 0.0 | 0.2 | GO:0043240 | Fanconi anaemia nuclear complex(GO:0043240) |
| 0.0 | 6.7 | GO:0031012 | extracellular matrix(GO:0031012) |
| 0.0 | 0.1 | GO:0070652 | HAUS complex(GO:0070652) |
| 0.0 | 0.1 | GO:0005955 | calcineurin complex(GO:0005955) |
| 0.0 | 1.4 | GO:0005795 | Golgi stack(GO:0005795) |
| 0.0 | 0.2 | GO:0034751 | aryl hydrocarbon receptor complex(GO:0034751) |
| 0.0 | 0.7 | GO:0031941 | filamentous actin(GO:0031941) |
| 0.0 | 0.1 | GO:0097255 | R2TP complex(GO:0097255) |
| 0.0 | 0.1 | GO:0032300 | mismatch repair complex(GO:0032300) |
| 0.0 | 0.9 | GO:0005761 | organellar ribosome(GO:0000313) mitochondrial ribosome(GO:0005761) |
| 0.0 | 0.3 | GO:0071144 | SMAD2-SMAD3 protein complex(GO:0071144) |
| 0.0 | 4.1 | GO:0005730 | nucleolus(GO:0005730) |
| 0.0 | 0.3 | GO:0035861 | site of double-strand break(GO:0035861) |
| 0.0 | 0.5 | GO:0032281 | AMPA glutamate receptor complex(GO:0032281) |
| 0.0 | 0.9 | GO:0005871 | kinesin complex(GO:0005871) |
| 0.0 | 0.2 | GO:0044665 | MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339) |
| 0.0 | 0.1 | GO:0016363 | nuclear matrix(GO:0016363) |
| 0.0 | 0.1 | GO:0016011 | dystroglycan complex(GO:0016011) sarcoglycan complex(GO:0016012) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.1 | 10.6 | GO:0009374 | biotin binding(GO:0009374) |
| 1.0 | 3.8 | GO:0030228 | lipoprotein particle receptor activity(GO:0030228) |
| 0.3 | 3.3 | GO:0035804 | structural constituent of egg coat(GO:0035804) |
| 0.3 | 0.9 | GO:0071077 | coenzyme A transmembrane transporter activity(GO:0015228) adenosine 3',5'-bisphosphate transmembrane transporter activity(GO:0071077) AMP transmembrane transporter activity(GO:0080122) |
| 0.3 | 0.8 | GO:0016509 | long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509) |
| 0.2 | 1.4 | GO:0032190 | acrosin binding(GO:0032190) |
| 0.2 | 2.0 | GO:0003834 | beta-carotene 15,15'-monooxygenase activity(GO:0003834) carotenoid dioxygenase activity(GO:0010436) |
| 0.2 | 0.9 | GO:0052905 | tRNA (guanine(9)-N(1))-methyltransferase activity(GO:0052905) |
| 0.2 | 0.9 | GO:0008488 | gamma-glutamyl carboxylase activity(GO:0008488) |
| 0.2 | 0.8 | GO:0004534 | 5'-3' exoribonuclease activity(GO:0004534) |
| 0.2 | 1.8 | GO:0052629 | phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629) |
| 0.2 | 1.7 | GO:0017091 | AU-rich element binding(GO:0017091) mRNA 3'-UTR AU-rich region binding(GO:0035925) |
| 0.2 | 0.5 | GO:0019777 | Atg12 transferase activity(GO:0019777) |
| 0.2 | 1.1 | GO:0004430 | 1-phosphatidylinositol 4-kinase activity(GO:0004430) |
| 0.1 | 1.0 | GO:0070698 | type I activin receptor binding(GO:0070698) |
| 0.1 | 1.0 | GO:0008526 | phosphatidylinositol transporter activity(GO:0008526) |
| 0.1 | 1.1 | GO:0016530 | metallochaperone activity(GO:0016530) |
| 0.1 | 0.7 | GO:0043139 | 5'-3' DNA helicase activity(GO:0043139) |
| 0.1 | 0.4 | GO:0048030 | disaccharide binding(GO:0048030) |
| 0.1 | 1.0 | GO:0042500 | aspartic endopeptidase activity, intramembrane cleaving(GO:0042500) |
| 0.1 | 0.5 | GO:0061656 | SUMO conjugating enzyme activity(GO:0061656) |
| 0.1 | 0.8 | GO:0017176 | phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176) |
| 0.1 | 1.4 | GO:0015129 | lactate transmembrane transporter activity(GO:0015129) |
| 0.1 | 0.5 | GO:0004660 | protein farnesyltransferase activity(GO:0004660) |
| 0.1 | 1.4 | GO:0004711 | ribosomal protein S6 kinase activity(GO:0004711) |
| 0.1 | 0.6 | GO:0003997 | acyl-CoA oxidase activity(GO:0003997) |
| 0.1 | 0.5 | GO:0015140 | thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131) malate transmembrane transporter activity(GO:0015140) |
| 0.1 | 0.5 | GO:0034431 | endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) |
| 0.1 | 0.3 | GO:0004113 | 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity(GO:0004113) |
| 0.1 | 0.5 | GO:1990756 | protein binding, bridging involved in substrate recognition for ubiquitination(GO:1990756) |
| 0.1 | 1.2 | GO:0005025 | transforming growth factor beta receptor activity, type I(GO:0005025) |
| 0.1 | 0.3 | GO:0008440 | inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) |
| 0.1 | 0.4 | GO:0031005 | filamin binding(GO:0031005) |
| 0.1 | 1.1 | GO:0043028 | cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) cysteine-type endopeptidase regulator activity involved in apoptotic process(GO:0043028) |
| 0.1 | 0.6 | GO:0004095 | carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416) |
| 0.1 | 0.9 | GO:0015183 | L-aspartate transmembrane transporter activity(GO:0015183) |
| 0.1 | 0.5 | GO:0005068 | transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068) |
| 0.1 | 0.3 | GO:0010521 | telomerase inhibitor activity(GO:0010521) |
| 0.1 | 0.3 | GO:0070513 | death domain binding(GO:0070513) |
| 0.1 | 2.5 | GO:0005540 | hyaluronic acid binding(GO:0005540) |
| 0.1 | 1.7 | GO:0003688 | DNA replication origin binding(GO:0003688) |
| 0.1 | 0.6 | GO:0004865 | protein serine/threonine phosphatase inhibitor activity(GO:0004865) |
| 0.1 | 0.4 | GO:0003938 | IMP dehydrogenase activity(GO:0003938) |
| 0.1 | 1.1 | GO:0061608 | nuclear import signal receptor activity(GO:0061608) |
| 0.1 | 0.2 | GO:0015119 | hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513) |
| 0.1 | 1.1 | GO:0008449 | N-acetylglucosamine-6-sulfatase activity(GO:0008449) |
| 0.1 | 0.8 | GO:0061665 | SUMO ligase activity(GO:0061665) |
| 0.1 | 0.7 | GO:0047676 | arachidonate-CoA ligase activity(GO:0047676) |
| 0.1 | 0.2 | GO:0051139 | calcium:proton antiporter activity(GO:0015369) metal ion:proton antiporter activity(GO:0051139) |
| 0.1 | 3.9 | GO:0003727 | single-stranded RNA binding(GO:0003727) |
| 0.1 | 0.2 | GO:0004419 | hydroxymethylglutaryl-CoA lyase activity(GO:0004419) |
| 0.1 | 1.7 | GO:0000030 | mannosyltransferase activity(GO:0000030) |
| 0.1 | 0.8 | GO:0032051 | clathrin light chain binding(GO:0032051) |
| 0.1 | 1.6 | GO:0030165 | PDZ domain binding(GO:0030165) |
| 0.1 | 0.2 | GO:0004311 | farnesyltranstransferase activity(GO:0004311) |
| 0.1 | 0.4 | GO:0004523 | RNA-DNA hybrid ribonuclease activity(GO:0004523) |
| 0.1 | 0.2 | GO:0022889 | serine transmembrane transporter activity(GO:0022889) |
| 0.1 | 0.2 | GO:0004064 | arylesterase activity(GO:0004064) |
| 0.1 | 1.0 | GO:0015095 | magnesium ion transmembrane transporter activity(GO:0015095) |
| 0.0 | 2.3 | GO:0019706 | protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707) |
| 0.0 | 0.2 | GO:0004001 | adenosine kinase activity(GO:0004001) |
| 0.0 | 0.5 | GO:0035259 | glucocorticoid receptor binding(GO:0035259) |
| 0.0 | 1.0 | GO:0019894 | kinesin binding(GO:0019894) |
| 0.0 | 0.6 | GO:0004415 | hyalurononglucosaminidase activity(GO:0004415) |
| 0.0 | 0.7 | GO:0031726 | CCR1 chemokine receptor binding(GO:0031726) CCR4 chemokine receptor binding(GO:0031729) |
| 0.0 | 0.3 | GO:0080019 | fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019) |
| 0.0 | 2.5 | GO:0005178 | integrin binding(GO:0005178) |
| 0.0 | 0.2 | GO:0030942 | endoplasmic reticulum signal peptide binding(GO:0030942) |
| 0.0 | 2.9 | GO:0031625 | ubiquitin protein ligase binding(GO:0031625) |
| 0.0 | 0.5 | GO:0047372 | acylglycerol lipase activity(GO:0047372) |
| 0.0 | 0.2 | GO:0043023 | ribosomal large subunit binding(GO:0043023) |
| 0.0 | 0.6 | GO:0051879 | Hsp90 protein binding(GO:0051879) |
| 0.0 | 1.6 | GO:0005109 | frizzled binding(GO:0005109) |
| 0.0 | 0.3 | GO:0019871 | sodium channel inhibitor activity(GO:0019871) |
| 0.0 | 8.7 | GO:0042802 | identical protein binding(GO:0042802) |
| 0.0 | 0.1 | GO:0003960 | NADPH:quinone reductase activity(GO:0003960) |
| 0.0 | 0.1 | GO:0070336 | flap-structured DNA binding(GO:0070336) |
| 0.0 | 0.1 | GO:0016649 | electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649) |
| 0.0 | 0.3 | GO:0046625 | sphingolipid binding(GO:0046625) ceramide binding(GO:0097001) |
| 0.0 | 0.7 | GO:0031492 | nucleosomal DNA binding(GO:0031492) |
| 0.0 | 0.2 | GO:0004408 | holocytochrome-c synthase activity(GO:0004408) |
| 0.0 | 0.4 | GO:0003886 | DNA (cytosine-5-)-methyltransferase activity(GO:0003886) |
| 0.0 | 2.1 | GO:0003678 | DNA helicase activity(GO:0003678) |
| 0.0 | 0.1 | GO:0008179 | adenylate cyclase binding(GO:0008179) |
| 0.0 | 0.3 | GO:0004465 | lipoprotein lipase activity(GO:0004465) |
| 0.0 | 1.1 | GO:0019003 | GDP binding(GO:0019003) |
| 0.0 | 0.6 | GO:0042800 | histone methyltransferase activity (H3-K4 specific)(GO:0042800) |
| 0.0 | 0.5 | GO:0097602 | cullin family protein binding(GO:0097602) |
| 0.0 | 0.2 | GO:0010859 | calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859) |
| 0.0 | 0.2 | GO:0031826 | type 2A serotonin receptor binding(GO:0031826) |
| 0.0 | 7.4 | GO:0003729 | mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822) |
| 0.0 | 1.6 | GO:0016627 | oxidoreductase activity, acting on the CH-CH group of donors(GO:0016627) |
| 0.0 | 0.4 | GO:0016018 | cyclosporin A binding(GO:0016018) |
| 0.0 | 0.2 | GO:0051998 | carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998) |
| 0.0 | 0.2 | GO:0001517 | N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517) |
| 0.0 | 0.3 | GO:0001102 | RNA polymerase II activating transcription factor binding(GO:0001102) |
| 0.0 | 0.2 | GO:0015204 | urea transmembrane transporter activity(GO:0015204) |
| 0.0 | 0.2 | GO:0008296 | 3'-5'-exodeoxyribonuclease activity(GO:0008296) |
| 0.0 | 0.1 | GO:0016793 | dGTPase activity(GO:0008832) triphosphoric monoester hydrolase activity(GO:0016793) |
| 0.0 | 0.2 | GO:0005042 | netrin receptor activity(GO:0005042) |
| 0.0 | 0.2 | GO:0015924 | mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) mannosyl-oligosaccharide mannosidase activity(GO:0015924) |
| 0.0 | 0.7 | GO:0008013 | beta-catenin binding(GO:0008013) |
| 0.0 | 0.1 | GO:0004594 | pantothenate kinase activity(GO:0004594) |
| 0.0 | 0.9 | GO:0003697 | single-stranded DNA binding(GO:0003697) |
| 0.0 | 0.1 | GO:0004449 | isocitrate dehydrogenase (NAD+) activity(GO:0004449) |
| 0.0 | 0.1 | GO:0004984 | olfactory receptor activity(GO:0004984) |
| 0.0 | 0.1 | GO:0036042 | long-chain fatty acyl-CoA binding(GO:0036042) |
| 0.0 | 0.1 | GO:0033188 | sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493) |
| 0.0 | 0.1 | GO:0070888 | E-box binding(GO:0070888) |
| 0.0 | 1.2 | GO:0004715 | non-membrane spanning protein tyrosine kinase activity(GO:0004715) |
| 0.0 | 0.1 | GO:0004723 | calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192) |
| 0.0 | 0.1 | GO:0042609 | CD4 receptor binding(GO:0042609) |
| 0.0 | 0.1 | GO:0005172 | vascular endothelial growth factor receptor binding(GO:0005172) |
| 0.0 | 0.4 | GO:1904315 | neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315) |
| 0.0 | 0.1 | GO:0016521 | pituitary adenylate cyclase activating polypeptide activity(GO:0016521) |
| 0.0 | 0.3 | GO:0070411 | I-SMAD binding(GO:0070411) |
| 0.0 | 0.3 | GO:0051393 | muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393) |
| 0.0 | 0.4 | GO:0008195 | phosphatidate phosphatase activity(GO:0008195) |
| 0.0 | 0.1 | GO:0008568 | microtubule-severing ATPase activity(GO:0008568) |
| 0.0 | 2.5 | GO:0042393 | histone binding(GO:0042393) |
| 0.0 | 0.6 | GO:0017022 | myosin binding(GO:0017022) |
| 0.0 | 0.4 | GO:0005347 | ATP transmembrane transporter activity(GO:0005347) |
| 0.0 | 0.2 | GO:0000062 | fatty-acyl-CoA binding(GO:0000062) |
| 0.0 | 0.1 | GO:0042975 | peroxisome proliferator activated receptor binding(GO:0042975) |
| 0.0 | 2.2 | GO:0004725 | protein tyrosine phosphatase activity(GO:0004725) |
| 0.0 | 0.1 | GO:0016863 | intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863) |
| 0.0 | 0.1 | GO:0004692 | cGMP-dependent protein kinase activity(GO:0004692) |
| 0.0 | 0.1 | GO:0001733 | galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694) |
| 0.0 | 0.2 | GO:0016251 | obsolete general RNA polymerase II transcription factor activity(GO:0016251) |
| 0.0 | 0.3 | GO:0098632 | protein binding involved in cell adhesion(GO:0098631) protein binding involved in cell-cell adhesion(GO:0098632) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 3.8 | PID REELIN PATHWAY | Reelin signaling pathway |
| 0.2 | 2.9 | PID INTEGRIN2 PATHWAY | Beta2 integrin cell surface interactions |
| 0.1 | 2.6 | NABA PROTEOGLYCANS | Genes encoding proteoglycans |
| 0.1 | 2.7 | PID CASPASE PATHWAY | Caspase cascade in apoptosis |
| 0.1 | 1.3 | PID HIF2PATHWAY | HIF-2-alpha transcription factor network |
| 0.0 | 0.3 | SA FAS SIGNALING | The TNF-type receptor Fas induces apoptosis on ligand binding. |
| 0.0 | 0.5 | PID TCR CALCIUM PATHWAY | Calcium signaling in the CD4+ TCR pathway |
| 0.0 | 0.9 | PID NECTIN PATHWAY | Nectin adhesion pathway |
| 0.0 | 1.0 | ST TUMOR NECROSIS FACTOR PATHWAY | Tumor Necrosis Factor Pathway. |
| 0.0 | 0.2 | SA PROGRAMMED CELL DEATH | Programmed cell death, or apoptosis, eliminates damaged or unneeded cells. |
| 0.0 | 0.4 | PID IL12 STAT4 PATHWAY | IL12 signaling mediated by STAT4 |
| 0.0 | 0.9 | PID PRL SIGNALING EVENTS PATHWAY | Signaling events mediated by PRL |
| 0.0 | 0.5 | PID LPA4 PATHWAY | LPA4-mediated signaling events |
| 0.0 | 0.6 | PID WNT NONCANONICAL PATHWAY | Noncanonical Wnt signaling pathway |
| 0.0 | 0.5 | PID P38 MKK3 6PATHWAY | p38 MAPK signaling pathway |
| 0.0 | 0.5 | PID RXR VDR PATHWAY | RXR and RAR heterodimerization with other nuclear receptor |
| 0.0 | 1.0 | NABA COLLAGENS | Genes encoding collagen proteins |
| 0.0 | 0.8 | PID AURORA B PATHWAY | Aurora B signaling |
| 0.0 | 1.1 | PID MTOR 4PATHWAY | mTOR signaling pathway |
| 0.0 | 0.3 | PID SMAD2 3PATHWAY | Regulation of cytoplasmic and nuclear SMAD2/3 signaling |
| 0.0 | 1.1 | PID TELOMERASE PATHWAY | Regulation of Telomerase |
| 0.0 | 0.3 | PID CERAMIDE PATHWAY | Ceramide signaling pathway |
| 0.0 | 0.1 | PID SYNDECAN 1 PATHWAY | Syndecan-1-mediated signaling events |
| 0.0 | 0.2 | PID CIRCADIAN PATHWAY | Circadian rhythm pathway |
| 0.0 | 0.1 | PID GMCSF PATHWAY | GMCSF-mediated signaling events |
| 0.0 | 0.4 | PID EPO PATHWAY | EPO signaling pathway |
| 0.0 | 1.1 | WNT SIGNALING | Genes related to Wnt-mediated signal transduction |
| 0.0 | 0.7 | PID AR PATHWAY | Coregulation of Androgen receptor activity |
| 0.0 | 0.2 | PID ARF 3PATHWAY | Arf1 pathway |
| 0.0 | 0.2 | PID HNF3A PATHWAY | FOXA1 transcription factor network |
| 0.0 | 1.6 | NABA ECM REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
| 0.0 | 0.2 | PID ALPHA SYNUCLEIN PATHWAY | Alpha-synuclein signaling |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 1.1 | REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK | Genes involved in Regulation of Rheb GTPase activity by AMPK |
| 0.2 | 2.8 | REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX | Genes involved in Association of licensing factors with the pre-replicative complex |
| 0.1 | 2.7 | REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS | Genes involved in Apoptotic cleavage of cellular proteins |
| 0.1 | 1.5 | REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS | Genes involved in Bile salt and organic anion SLC transporters |
| 0.1 | 0.9 | REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS | Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins |
| 0.1 | 1.7 | REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE | Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase |
| 0.1 | 0.9 | REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE | Genes involved in Synthesis of PIPs at the late endosome membrane |
| 0.1 | 1.5 | REACTOME GLUCONEOGENESIS | Genes involved in Gluconeogenesis |
| 0.1 | 1.1 | REACTOME DESTABILIZATION OF MRNA BY KSRP | Genes involved in Destabilization of mRNA by KSRP |
| 0.1 | 0.9 | REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI | Genes involved in Synthesis of glycosylphosphatidylinositol (GPI) |
| 0.0 | 0.7 | REACTOME GLUTATHIONE CONJUGATION | Genes involved in Glutathione conjugation |
| 0.0 | 0.6 | REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE | Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle |
| 0.0 | 1.5 | REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN | Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein |
| 0.0 | 0.4 | REACTOME SIGNALING BY NODAL | Genes involved in Signaling by NODAL |
| 0.0 | 0.3 | REACTOME SEMA3A PAK DEPENDENT AXON REPULSION | Genes involved in Sema3A PAK dependent Axon repulsion |
| 0.0 | 0.5 | REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY | Genes involved in Adenylate cyclase activating pathway |
| 0.0 | 0.9 | REACTOME ADHERENS JUNCTIONS INTERACTIONS | Genes involved in Adherens junctions interactions |
| 0.0 | 0.6 | REACTOME OTHER SEMAPHORIN INTERACTIONS | Genes involved in Other semaphorin interactions |
| 0.0 | 0.8 | REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION | Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation |
| 0.0 | 0.6 | REACTOME KINESINS | Genes involved in Kinesins |
| 0.0 | 0.6 | REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION | Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription |
| 0.0 | 1.2 | REACTOME COLLAGEN FORMATION | Genes involved in Collagen formation |
| 0.0 | 0.3 | REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 | Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1 |
| 0.0 | 0.6 | REACTOME SIGNALING BY FGFR1 FUSION MUTANTS | Genes involved in Signaling by FGFR1 fusion mutants |
| 0.0 | 0.5 | REACTOME PEROXISOMAL LIPID METABOLISM | Genes involved in Peroxisomal lipid metabolism |
| 0.0 | 0.4 | REACTOME REGULATION OF KIT SIGNALING | Genes involved in Regulation of KIT signaling |
| 0.0 | 0.3 | REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION | Genes involved in Mitochondrial Fatty Acid Beta-Oxidation |
| 0.0 | 0.4 | REACTOME BASE EXCISION REPAIR | Genes involved in Base Excision Repair |
| 0.0 | 0.2 | REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION | Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation |
| 0.0 | 0.8 | REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS | Genes involved in Association of TriC/CCT with target proteins during biosynthesis |
| 0.0 | 0.5 | REACTOME PIP3 ACTIVATES AKT SIGNALING | Genes involved in PIP3 activates AKT signaling |
| 0.0 | 0.3 | REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY | Genes involved in Post-chaperonin tubulin folding pathway |
| 0.0 | 0.4 | REACTOME CHOLESTEROL BIOSYNTHESIS | Genes involved in Cholesterol biosynthesis |
| 0.0 | 0.2 | REACTOME INTRINSIC PATHWAY | Genes involved in Intrinsic Pathway |
| 0.0 | 0.2 | REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA | Genes involved in Activation of Chaperones by ATF6-alpha |
| 0.0 | 0.8 | REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION | Genes involved in Transport to the Golgi and subsequent modification |
| 0.0 | 0.7 | REACTOME MITOCHONDRIAL PROTEIN IMPORT | Genes involved in Mitochondrial Protein Import |
| 0.0 | 0.5 | REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS | Genes involved in Transport of Ribonucleoproteins into the Host Nucleus |
| 0.0 | 0.2 | REACTOME HS GAG DEGRADATION | Genes involved in HS-GAG degradation |
| 0.0 | 0.1 | REACTOME DARPP 32 EVENTS | Genes involved in DARPP-32 events |
| 0.0 | 0.1 | REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS | Genes involved in Trafficking of GluR2-containing AMPA receptors |
| 0.0 | 0.6 | REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 | Genes involved in Response to elevated platelet cytosolic Ca2+ |