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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for ets2

Z-value: 1.07

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Transcription factors associated with ets2

Gene Symbol Gene ID Gene Info
ets2
ENSDARG00000103980 v-ets avian erythroblastosis virus E26 oncogene homolog 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ets2dr11_v1_chr10_+_187760_187764-0.194.4e-01Click!

Activity profile of ets2 motif

Sorted Z-values of ets2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr8_-_50135492 3.31 ENSDART00000149398
si:ch73-132k15.2
si:ch73-132k15.2
chr11_+_18183220 3.09 ENSDART00000113468
LO018315.10

chr12_-_42368296 2.84 ENSDART00000171075
zgc:111868
zgc:111868
chr20_+_54304800 2.76 ENSDART00000121661
zp2.6
zona pellucida glycoprotein 2, tandem duplicate 6
chr11_+_18130300 2.72 ENSDART00000169146
zgc:175135
zgc:175135
chr11_+_18037729 2.72 ENSDART00000111624
zgc:175135
zgc:175135
chr10_-_8046764 2.71 ENSDART00000099031
zgc:136254
zgc:136254
chr11_+_18053333 2.68 ENSDART00000075750
zgc:175135
zgc:175135
chr11_+_18157260 2.63 ENSDART00000144659
zgc:173545
zgc:173545
chr11_+_18175893 2.61 ENSDART00000177625
zgc:173545
zgc:173545
chr20_+_54312970 2.61 ENSDART00000024598
ENSDART00000193172
zp2.5
zona pellucida glycoprotein 2, tandem duplicate 5
chr20_+_54299419 2.55 ENSDART00000056089
ENSDART00000193107
si:zfos-1505d6.3
si:zfos-1505d6.3
chr20_+_54309148 2.52 ENSDART00000099360
zp2.1
zona pellucida glycoprotein 2, tandem duplicate 1
chr20_+_54290356 2.41 ENSDART00000173347
zp2.2
zona pellucida glycoprotein 2, tandem duplicate 2
chr20_+_54295213 2.24 ENSDART00000074085
zp2.3
zona pellucida glycoprotein 2, tandem duplicate 3
chr12_-_4301234 2.12 ENSDART00000152377
ENSDART00000152521
ca15b
carbonic anhydrase XVb
chr10_-_8053385 2.07 ENSDART00000142714
si:ch211-251f6.7
si:ch211-251f6.7
chr10_-_8053753 2.06 ENSDART00000162289
si:ch211-251f6.7
si:ch211-251f6.7
chr1_+_38818268 2.00 ENSDART00000166864
spcs3
signal peptidase complex subunit 3
chr1_+_59314675 1.65 ENSDART00000161872
ENSDART00000160658
ENSDART00000169792
ENSDART00000160735
parn
poly(A)-specific ribonuclease (deadenylation nuclease)
chr1_-_18848955 1.62 ENSDART00000109294
ENSDART00000146410
zgc:195282
zgc:195282
chr15_+_34939906 1.55 ENSDART00000131182
si:ch73-95l15.3
si:ch73-95l15.3
chr19_-_22843480 1.47 ENSDART00000052503
nudcd1
NudC domain containing 1
chr15_+_34940098 1.47 ENSDART00000099703
si:ch73-95l15.3
si:ch73-95l15.3
chr16_+_35401543 1.42 ENSDART00000171608
rab42b
RAB42, member RAS oncogene family
chr15_+_34934568 1.37 ENSDART00000165210
zgc:66024
zgc:66024
chr15_+_34946779 1.36 ENSDART00000192661
ENSDART00000188800
ENSDART00000156515
si:ch73-95l15.5
zgc:55621
si:ch73-95l15.5
zgc:55621
chr20_-_164300 1.32 ENSDART00000183354
si:ch211-241j12.3
si:ch211-241j12.3
chr20_-_4031475 1.31 ENSDART00000112053
fam89a
family with sequence similarity 89, member A
chr19_+_26340736 1.28 ENSDART00000013497
mylipa
myosin regulatory light chain interacting protein a
chr14_-_897874 1.26 ENSDART00000167395
rgs14a
regulator of G protein signaling 14a
chr6_-_33924883 1.23 ENSDART00000132762
ENSDART00000148142
ENSDART00000142213
akr1a1b
aldo-keto reductase family 1, member A1b (aldehyde reductase)
chr16_+_38201840 1.23 ENSDART00000044971
myo1eb
myosin IE, b
chr6_-_15065376 1.21 ENSDART00000087797
tgfbrap1
transforming growth factor, beta receptor associated protein 1
chr25_+_2361721 1.20 ENSDART00000172905
zmp:0000000932
zmp:0000000932
chr5_-_32336613 1.18 ENSDART00000139732
dab2
Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
chr1_-_8653385 1.18 ENSDART00000193041
actb1
actin, beta 1
chr21_-_5056812 1.16 ENSDART00000139713
ENSDART00000140859
zgc:77838
zgc:77838
chr7_-_8324927 1.15 ENSDART00000102535
f13a1b
coagulation factor XIII, A1 polypeptide b
chr17_-_24890843 1.13 ENSDART00000184984
ENSDART00000135569
ENSDART00000193661
gale
UDP-galactose-4-epimerase
chr16_+_53603945 1.12 ENSDART00000083513
sacm1lb
SAC1 like phosphatidylinositide phosphatase b
chr20_-_36800002 1.12 ENSDART00000015190
ptrhd1
peptidyl-tRNA hydrolase domain containing 1
chr6_-_33925381 1.12 ENSDART00000137268
ENSDART00000145019
ENSDART00000141822
akr1a1b
aldo-keto reductase family 1, member A1b (aldehyde reductase)
chr14_-_16807206 1.09 ENSDART00000157957
tcirg1b
T cell immune regulator 1, ATPase H+ transporting V0 subunit a3b
chr2_+_30249977 1.09 ENSDART00000109160
ENSDART00000135171
tmem70
transmembrane protein 70
chr10_+_29771256 1.05 ENSDART00000193195
hyou1
hypoxia up-regulated 1
chr7_-_38687431 1.04 ENSDART00000074490
aplnr2
apelin receptor 2
chr18_-_49286381 1.04 ENSDART00000174248
ENSDART00000174038
si:zfos-464b6.2
si:zfos-464b6.2
chr17_+_21126495 1.04 ENSDART00000022830
pygb
phosphorylase, glycogen; brain
chr11_-_34219211 1.02 ENSDART00000098472
tmem44
transmembrane protein 44
chr10_+_36197968 1.02 ENSDART00000114102
COA4
si:ch211-215a9.5
chr5_-_69482891 1.02 ENSDART00000109487
CABZ01032476.1

chr2_+_37207461 1.01 ENSDART00000138952
ENSDART00000132856
ENSDART00000137272
ENSDART00000143468
apoda.2
apolipoprotein Da, duplicate 2
chr20_+_27087539 1.00 ENSDART00000062094
tmem251
transmembrane protein 251
chr21_-_38717854 1.00 ENSDART00000065169
ENSDART00000113813
siah2l
seven in absentia homolog 2 (Drosophila)-like
chr10_+_15608326 1.00 ENSDART00000188770
zfand5b
zinc finger, AN1-type domain 5b
chr7_+_29096194 0.99 ENSDART00000052349
ogfod1
2-oxoglutarate and iron-dependent oxygenase domain containing 1
chr12_-_48312647 0.97 ENSDART00000114415
ascc1
activating signal cointegrator 1 complex subunit 1
chr25_-_30357027 0.96 ENSDART00000171137
pdia3
protein disulfide isomerase family A, member 3
chr11_-_574423 0.96 ENSDART00000176364
ENSDART00000130504
mkrn2
makorin, ring finger protein, 2
chr10_+_7671260 0.96 ENSDART00000157608
fam136a
family with sequence similarity 136, member A
chr18_+_7543347 0.96 ENSDART00000103467
arf5
ADP-ribosylation factor 5
chr17_+_51682429 0.94 ENSDART00000004379
nol10
nucleolar protein 10
chr2_-_9818640 0.94 ENSDART00000139499
ENSDART00000165548
ENSDART00000012442
ENSDART00000046587
ap2m1b
adaptor-related protein complex 2, mu 1 subunit, b
chr1_+_59321629 0.94 ENSDART00000161981
parn
poly(A)-specific ribonuclease (deadenylation nuclease)
chr16_+_43368572 0.94 ENSDART00000032778
ENSDART00000193897
rnf144b
ring finger protein 144B
chr11_-_38533505 0.94 ENSDART00000113894
slc45a3
solute carrier family 45, member 3
chr22_+_20710434 0.93 ENSDART00000135521
peak3
PEAK family member 3
chr12_+_28955766 0.93 ENSDART00000123417
ENSDART00000139347
znf668
zinc finger protein 668
chr12_+_22576404 0.92 ENSDART00000172053
capgb
capping protein (actin filament), gelsolin-like b
chr19_-_43757568 0.92 ENSDART00000058491
ppt1
palmitoyl-protein thioesterase 1 (ceroid-lipofuscinosis, neuronal 1, infantile)
chr5_+_4298636 0.92 ENSDART00000100061
prdx4
peroxiredoxin 4
chr18_+_17600570 0.91 ENSDART00000175258
ENSDART00000151850
ENSDART00000151934
herpud1
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
chr21_-_12749501 0.91 ENSDART00000179724
LO018011.1

chr7_+_24528866 0.90 ENSDART00000180552
si:dkeyp-75h12.2
si:dkeyp-75h12.2
chr10_+_2684958 0.90 ENSDART00000112019
setd9
SET domain containing 9
chr4_+_12966640 0.90 ENSDART00000113357
vhll
von Hippel-Lindau tumor suppressor like
chr11_-_35756468 0.90 ENSDART00000103076
arl8bb
ADP-ribosylation factor-like 8Bb
chr5_-_7513082 0.89 ENSDART00000158913
bmpr1ba
bone morphogenetic protein receptor, type IBa
chr6_+_112579 0.88 ENSDART00000034505
ap1m2
adaptor-related protein complex 1, mu 2 subunit
chr3_-_6608342 0.88 ENSDART00000161188
si:ch73-59f11.3
si:ch73-59f11.3
chr11_-_3535537 0.87 ENSDART00000165329
ENSDART00000009788
ddx19
DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 19 (DBP5 homolog, yeast)
chr7_+_24528430 0.87 ENSDART00000133022
si:dkeyp-75h12.2
si:dkeyp-75h12.2
chr1_-_8646941 0.86 ENSDART00000103644
fbxl18
F-box and leucine-rich repeat protein 18
chr19_-_29887629 0.86 ENSDART00000066123
kpna6
karyopherin alpha 6 (importin alpha 7)
chr3_-_27647845 0.85 ENSDART00000151625
si:ch211-157c3.4
si:ch211-157c3.4
chr16_-_25233515 0.85 ENSDART00000058943
zgc:110182
zgc:110182
chr9_+_14023942 0.85 ENSDART00000142749
si:ch211-67e16.4
si:ch211-67e16.4
chr4_-_2637689 0.85 ENSDART00000192550
ENSDART00000021953
ENSDART00000150344
cog5
component of oligomeric golgi complex 5
chr13_+_41917606 0.84 ENSDART00000114741
polr1b
polymerase (RNA) I polypeptide B
chr3_+_19665319 0.84 ENSDART00000007857
ENSDART00000193509
mettl2a
methyltransferase like 2A
chr10_-_7671219 0.83 ENSDART00000159330
pcyox1
prenylcysteine oxidase 1
chr13_+_28580357 0.83 ENSDART00000007211
wbp1la
WW domain binding protein 1-like a
chr19_+_47476908 0.81 ENSDART00000157886
zgc:114119
zgc:114119
chr1_-_55044256 0.81 ENSDART00000165505
ENSDART00000167536
ENSDART00000170001
vps54
vacuolar protein sorting 54 homolog (S. cerevisiae)
chr1_-_44928987 0.81 ENSDART00000134635
si:dkey-9i23.15
si:dkey-9i23.15
chr11_+_22109887 0.80 ENSDART00000122136
MDFI
si:dkey-91m3.1
chr21_+_28747069 0.80 ENSDART00000014058
zgc:100829
zgc:100829
chr1_+_26480890 0.80 ENSDART00000164430
uso1
USO1 vesicle transport factor
chr21_+_28747236 0.80 ENSDART00000137874
zgc:100829
zgc:100829
chr8_-_1266181 0.80 ENSDART00000148654
ENSDART00000149924
cdc14b
cell division cycle 14B
chr20_+_51813432 0.78 ENSDART00000127444
taf1a
TATA box binding protein (TBP)-associated factor, RNA polymerase I, A
chr15_-_11683529 0.77 ENSDART00000161445
fkrp
fukutin related protein
chr2_-_32512648 0.77 ENSDART00000170674
abcf2a
ATP-binding cassette, sub-family F (GCN20), member 2a
chr4_-_17823424 0.77 ENSDART00000024822
dnajb9b
DnaJ (Hsp40) homolog, subfamily B, member 9b
chr7_-_59564011 0.77 ENSDART00000186053
zgc:112271
zgc:112271
chr4_-_330748 0.77 ENSDART00000067488
mrps10
mitochondrial ribosomal protein S10
chr8_+_36500061 0.76 ENSDART00000185840
slc7a4
solute carrier family 7, member 4
chr5_-_54712159 0.76 ENSDART00000149207
ccnb1
cyclin B1
chr16_+_47207691 0.76 ENSDART00000062507
ica1
islet cell autoantigen 1
chr6_-_39631164 0.75 ENSDART00000104042
ENSDART00000136076
atf7b
activating transcription factor 7b
chr1_-_46875493 0.73 ENSDART00000115081
agpat3
1-acylglycerol-3-phosphate O-acyltransferase 3
chr18_+_783936 0.73 ENSDART00000193357
rpp25b
ribonuclease P and MRP subunit p25, b
chr14_+_4178236 0.72 ENSDART00000162015
slc25a51b
solute carrier family 25, member 51b
chr3_+_56574623 0.71 ENSDART00000130877
rac1b
Rac family small GTPase 1b
chr18_+_10926197 0.71 ENSDART00000192387
ttc38
tetratricopeptide repeat domain 38
chr10_+_43039947 0.70 ENSDART00000193434
atg10
ATG10 autophagy related 10 homolog (S. cerevisiae)
chr7_-_26603743 0.69 ENSDART00000099003
plscr3b
phospholipid scramblase 3b
chr9_-_21238616 0.68 ENSDART00000191840
ENSDART00000189127
cox17
COX17 cytochrome c oxidase copper chaperone
chr5_+_36850650 0.68 ENSDART00000051186
nccrp1
non-specific cytotoxic cell receptor protein 1
chr11_+_24313931 0.67 ENSDART00000017599
ENSDART00000166045
rem1
RAS (RAD and GEM)-like GTP-binding 1
chr18_+_15271993 0.67 ENSDART00000099777
si:dkey-103i16.6
si:dkey-103i16.6
chr12_-_314899 0.67 ENSDART00000066579
pts
6-pyruvoyltetrahydropterin synthase
chr13_-_17860307 0.67 ENSDART00000135920
ENSDART00000054579
march8
membrane-associated ring finger (C3HC4) 8
chr12_+_47794089 0.67 ENSDART00000160726
polr3a
polymerase (RNA) III (DNA directed) polypeptide A
chr2_-_20715094 0.66 ENSDART00000155439
dusp12
dual specificity phosphatase 12
chr13_-_25408387 0.66 ENSDART00000002741
itprip
inositol 1,4,5-trisphosphate receptor interacting protein
chr13_-_5064481 0.66 ENSDART00000091806
ENSDART00000032322
abcg2c
ATP-binding cassette, sub-family G (WHITE), member 2c
chr7_+_11543999 0.66 ENSDART00000173676
il16
interleukin 16
chr21_-_9383974 0.65 ENSDART00000160932
sdad1
SDA1 domain containing 1
chr17_-_21368775 0.65 ENSDART00000058027
shtn1
shootin 1
chr14_-_41478265 0.64 ENSDART00000149886
ENSDART00000016002
tspan7
tetraspanin 7
chr4_-_23963838 0.63 ENSDART00000133433
ENSDART00000132615
ENSDART00000135942
ENSDART00000139439
celf2
cugbp, Elav-like family member 2
chr14_+_38878482 0.63 ENSDART00000043317
timm8a
translocase of inner mitochondrial membrane 8 homolog A (yeast)
chr24_-_1985007 0.62 ENSDART00000189870
PARD3 (1 of many)
par-3 family cell polarity regulator
chr1_-_48933 0.62 ENSDART00000171162
ildr1a
immunoglobulin-like domain containing receptor 1a
chr1_-_157563 0.62 ENSDART00000018741
pcid2
PCI domain containing 2
chr5_+_65040228 0.62 ENSDART00000164278
pmpca
peptidase (mitochondrial processing) alpha
chr10_+_35554219 0.62 ENSDART00000077373
zdhhc20a
zinc finger, DHHC-type containing 20a
chr16_+_54674556 0.62 ENSDART00000167040
pop1
POP1 homolog, ribonuclease P/MRP subunit
chr16_-_40426837 0.61 ENSDART00000193690
plekhf2
pleckstrin homology domain containing, family F (with FYVE domain) member 2
chr6_+_19689464 0.61 ENSDART00000164960
stx8
syntaxin 8
chr2_+_37815687 0.60 ENSDART00000166352
sdr39u1
short chain dehydrogenase/reductase family 39U, member 1
chr7_-_24112484 0.60 ENSDART00000111923
ajuba
ajuba LIM protein
chr14_-_28567845 0.60 ENSDART00000126095
insb
preproinsulin b
chr17_-_13007484 0.60 ENSDART00000156812
si:dkeyp-33b5.4
si:dkeyp-33b5.4
chr12_+_10443785 0.60 ENSDART00000029133
snu13b
SNU13 homolog, small nuclear ribonucleoprotein b (U4/U6.U5)
chr18_+_44849809 0.59 ENSDART00000097328
arfgap2
ADP-ribosylation factor GTPase activating protein 2
chr2_-_21167652 0.59 ENSDART00000185792
bmi1b
bmi1 polycomb ring finger oncogene 1b
chr8_-_11770092 0.58 ENSDART00000091684
anapc7
anaphase promoting complex subunit 7
chr8_-_21103522 0.58 ENSDART00000100283
aldh9a1a.1
aldehyde dehydrogenase 9 family, member A1a, tandem duplicate 1
chr2_-_34072018 0.58 ENSDART00000020786
ENSDART00000132274
eif2b3
eukaryotic translation initiation factor 2B, subunit 3 gamma
chr23_+_25879320 0.58 ENSDART00000124963
pkig
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
chr7_+_5904020 0.57 ENSDART00000172847
hist1h2a11
histone cluster 1 H2A family member 11
chr2_-_34072218 0.57 ENSDART00000184618
eif2b3
eukaryotic translation initiation factor 2B, subunit 3 gamma
chr2_-_37684641 0.57 ENSDART00000012191
hiat1a
hippocampus abundant transcript 1a
chr12_-_49168398 0.57 ENSDART00000186608
FO704624.1

chr7_+_59212666 0.57 ENSDART00000172046
dok1b
docking protein 1b
chr5_+_69733096 0.57 ENSDART00000169013
arl6ip4
ADP-ribosylation factor-like 6 interacting protein 4
chr6_-_46735380 0.56 ENSDART00000103455
tarbp2
TAR (HIV) RNA binding protein 2
chr21_+_5932140 0.56 ENSDART00000193767
rexo4
REX4 homolog, 3'-5' exonuclease
chr7_+_73295890 0.56 ENSDART00000174331
ENSDART00000174250
CABZ01083442.1

chr3_-_32831971 0.56 ENSDART00000075270
zgc:153733
zgc:153733
chr15_-_1485086 0.56 ENSDART00000191651
si:dkeyp-97b10.3
si:dkeyp-97b10.3
chr1_-_30568225 0.56 ENSDART00000144297
ENSDART00000164204
ubac2
UBA domain containing 2
chr12_-_33805366 0.55 ENSDART00000030566
galk1
galactokinase 1
chr17_+_27134806 0.55 ENSDART00000151901
rps6ka1
ribosomal protein S6 kinase a, polypeptide 1
chr12_+_23892972 0.55 ENSDART00000152852
svila
supervillin a
chr5_+_50953240 0.55 ENSDART00000148501
ENSDART00000149892
ENSDART00000190312
col4a3bpa
collagen, type IV, alpha 3 (Goodpasture antigen) binding protein a
chr15_-_15230264 0.55 ENSDART00000155400
rrp8
ribosomal RNA processing 8, methyltransferase, homolog (yeast)
chr6_-_49063085 0.54 ENSDART00000156124
si:ch211-105j21.9
si:ch211-105j21.9
chr22_-_22337382 0.54 ENSDART00000144684
si:ch211-129c21.1
si:ch211-129c21.1
chr6_-_40657653 0.53 ENSDART00000154359
ppil1
peptidylprolyl isomerase (cyclophilin)-like 1
chr25_-_24248000 0.53 ENSDART00000073527
spty2d1
SPT2 chromatin protein domain containing 1
chr16_-_46393154 0.53 ENSDART00000132154
si:ch73-59c19.1
si:ch73-59c19.1
chr11_+_19502297 0.53 ENSDART00000103987
psmd6
proteasome 26S subunit, non-ATPase 6
chr20_+_13141408 0.53 ENSDART00000034098
dtl
denticleless E3 ubiquitin protein ligase homolog (Drosophila)
chr18_+_27598755 0.53 ENSDART00000193808
cd82b
CD82 molecule b
chr15_-_739229 0.52 ENSDART00000153874
si:dkey-7i4.19
si:dkey-7i4.19
chr24_+_25822999 0.52 ENSDART00000109809
sh3kbp1
SH3-domain kinase binding protein 1
chr20_-_24183333 0.52 ENSDART00000025862
ENSDART00000153075
map3k7
mitogen-activated protein kinase kinase kinase 7
chr11_+_18873619 0.52 ENSDART00000176141
magi1b
membrane associated guanylate kinase, WW and PDZ domain containing 1b
chr3_-_5664123 0.51 ENSDART00000145866
si:ch211-106h11.1
si:ch211-106h11.1
chr16_-_30833519 0.51 ENSDART00000191321
ptk2ab
protein tyrosine kinase 2ab
chr21_+_3796196 0.51 ENSDART00000146754
spout1
SPOUT domain containing methyltransferase 1
chr17_-_14780578 0.50 ENSDART00000154690
si:ch211-266o15.1
si:ch211-266o15.1
chr6_-_28961660 0.49 ENSDART00000147285
tomm70a
translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae)
chr19_+_11978209 0.49 ENSDART00000111568
polr2k
polymerase (RNA) II (DNA directed) polypeptide K
chr21_+_3796620 0.49 ENSDART00000099535
ENSDART00000144515
spout1
SPOUT domain containing methyltransferase 1
chr14_+_52408619 0.49 ENSDART00000163856
noa1
nitric oxide associated 1
chr25_+_35889102 0.49 ENSDART00000023453
ENSDART00000125821
ENSDART00000135441
lsm14aa
LSM14A mRNA processing body assembly factor a
chr19_+_7292445 0.49 ENSDART00000026634
ccdc127b
coiled-coil domain containing 127b
chr4_+_5642696 0.48 ENSDART00000028941
mrps18a
mitochondrial ribosomal protein S18A
chr10_+_26118122 0.47 ENSDART00000079207
trim47
tripartite motif containing 47
chr11_+_24314148 0.47 ENSDART00000171491
rem1
RAS (RAD and GEM)-like GTP-binding 1
chr10_+_45089820 0.47 ENSDART00000175481
camk2b2
calcium/calmodulin-dependent protein kinase (CaM kinase) II beta 2
chr8_+_41647539 0.47 ENSDART00000136492
ENSDART00000138799
ENSDART00000134404
si:ch211-158d24.4
si:ch211-158d24.4
chr18_+_3140682 0.47 ENSDART00000166382
clns1a
chloride channel, nucleotide-sensitive, 1A
chr4_+_77957611 0.47 ENSDART00000156692
arfgap3
ADP-ribosylation factor GTPase activating protein 3
chr15_+_12436220 0.47 ENSDART00000169894
tmprss4a
transmembrane protease, serine 4a

Network of associatons between targets according to the STRING database.

First level regulatory network of ets2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.4 1.1 GO:0048205 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.3 2.8 GO:0006465 signal peptide processing(GO:0006465)
0.3 0.9 GO:1903069 regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903069)
0.3 0.8 GO:0043903 regulation of symbiosis, encompassing mutualism through parasitism(GO:0043903)
0.2 1.0 GO:0051661 maintenance of centrosome location(GO:0051661)
0.2 1.7 GO:0006012 galactose metabolic process(GO:0006012)
0.2 1.1 GO:1901841 regulation of high voltage-gated calcium channel activity(GO:1901841) negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.2 0.7 GO:0010847 regulation of chromatin assembly(GO:0010847)
0.2 4.2 GO:0008354 germ cell migration(GO:0008354)
0.2 0.6 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.2 0.6 GO:0035331 negative regulation of hippo signaling(GO:0035331) positive regulation of posttranscriptional gene silencing(GO:0060148) positive regulation of gene silencing by miRNA(GO:2000637)
0.2 0.8 GO:0048211 Golgi vesicle docking(GO:0048211)
0.2 1.4 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.2 0.7 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.2 0.8 GO:0030328 prenylated protein catabolic process(GO:0030327) prenylcysteine catabolic process(GO:0030328) prenylcysteine metabolic process(GO:0030329)
0.2 0.7 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.2 0.8 GO:0010332 response to gamma radiation(GO:0010332) cellular response to gamma radiation(GO:0071480)
0.2 1.0 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.2 0.8 GO:0060049 regulation of protein glycosylation(GO:0060049)
0.2 0.5 GO:1903573 negative regulation of response to endoplasmic reticulum stress(GO:1903573)
0.1 1.3 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.1 0.4 GO:0042245 RNA repair(GO:0042245)
0.1 1.2 GO:2000725 regulation of cardiocyte differentiation(GO:1905207) regulation of cardiac muscle cell differentiation(GO:2000725)
0.1 0.4 GO:0021531 spinal cord radial glial cell differentiation(GO:0021531)
0.1 0.7 GO:0006929 substrate-dependent cell migration(GO:0006929)
0.1 0.6 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.1 0.4 GO:1901503 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) cellular lipid biosynthetic process(GO:0097384) ether biosynthetic process(GO:1901503)
0.1 0.6 GO:0072677 eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.1 0.2 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.1 0.6 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.1 1.0 GO:0006449 regulation of translational termination(GO:0006449)
0.1 0.4 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.1 0.5 GO:0051792 medium-chain fatty acid biosynthetic process(GO:0051792)
0.1 0.5 GO:0010692 regulation of alkaline phosphatase activity(GO:0010692) negative regulation of alkaline phosphatase activity(GO:0010693)
0.1 1.0 GO:0042214 carotene metabolic process(GO:0016119) carotene catabolic process(GO:0016121) terpene metabolic process(GO:0042214) terpene catabolic process(GO:0046247)
0.1 0.5 GO:0016094 polyprenol biosynthetic process(GO:0016094)
0.1 5.2 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
0.1 1.4 GO:0061055 myotome development(GO:0061055)
0.1 0.4 GO:0010039 response to iron ion(GO:0010039)
0.1 0.4 GO:0006499 N-terminal protein myristoylation(GO:0006499) N-terminal peptidyl-glycine N-myristoylation(GO:0018008) protein myristoylation(GO:0018377)
0.1 0.5 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.1 0.9 GO:0061056 sclerotome development(GO:0061056)
0.1 0.3 GO:0018343 protein farnesylation(GO:0018343)
0.1 0.8 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.1 0.6 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.1 1.2 GO:0072378 blood coagulation, fibrin clot formation(GO:0072378)
0.1 0.7 GO:0072321 chaperone-mediated protein transport(GO:0072321)
0.1 0.2 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.1 1.0 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.1 0.4 GO:0014005 microglia development(GO:0014005)
0.1 0.8 GO:0071850 mitotic cell cycle arrest(GO:0071850)
0.1 0.9 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.1 0.3 GO:0006297 nucleotide-excision repair, DNA gap filling(GO:0006297)
0.1 1.1 GO:0007035 vacuolar acidification(GO:0007035) pH reduction(GO:0045851) intracellular pH reduction(GO:0051452)
0.1 1.0 GO:0009251 polysaccharide catabolic process(GO:0000272) glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.1 0.4 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.1 0.6 GO:0051673 membrane disruption in other organism(GO:0051673)
0.1 0.9 GO:0002084 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.1 0.7 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.1 0.3 GO:1901907 diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.1 0.5 GO:0072422 signal transduction involved in DNA integrity checkpoint(GO:0072401) signal transduction involved in DNA damage checkpoint(GO:0072422) signal transduction involved in G2 DNA damage checkpoint(GO:0072425)
0.1 0.3 GO:0006867 asparagine transport(GO:0006867)
0.1 7.5 GO:0048545 response to steroid hormone(GO:0048545)
0.1 0.3 GO:1903292 protein localization to Golgi membrane(GO:1903292)
0.1 0.7 GO:1901970 positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.1 0.5 GO:0034063 stress granule assembly(GO:0034063)
0.1 0.2 GO:0021785 branchiomotor neuron axon guidance(GO:0021785)
0.1 0.4 GO:0033206 meiotic cytokinesis(GO:0033206) polar body extrusion after meiotic divisions(GO:0040038)
0.1 1.8 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.1 0.4 GO:0044528 regulation of mitochondrial mRNA stability(GO:0044528)
0.1 0.7 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055)
0.1 0.3 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.1 0.7 GO:0050927 regulation of positive chemotaxis(GO:0050926) positive regulation of positive chemotaxis(GO:0050927) induction of positive chemotaxis(GO:0050930)
0.1 0.7 GO:0046688 response to copper ion(GO:0046688)
0.1 0.4 GO:0016139 glycoside metabolic process(GO:0016137) glycoside catabolic process(GO:0016139)
0.1 0.3 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898) positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.1 0.5 GO:0070307 lens fiber cell development(GO:0070307) lens fiber cell morphogenesis(GO:0070309)
0.1 0.4 GO:0097341 inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341)
0.0 0.8 GO:0019433 triglyceride catabolic process(GO:0019433)
0.0 1.5 GO:0051014 actin filament severing(GO:0051014)
0.0 0.3 GO:0097101 blood vessel endothelial cell fate specification(GO:0097101)
0.0 0.2 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.0 0.4 GO:0055015 ventricular cardiac muscle cell development(GO:0055015)
0.0 0.6 GO:0001881 receptor recycling(GO:0001881)
0.0 0.6 GO:0070306 lens fiber cell differentiation(GO:0070306)
0.0 0.2 GO:0044806 G-quadruplex DNA unwinding(GO:0044806)
0.0 0.6 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.0 2.0 GO:0030490 maturation of SSU-rRNA(GO:0030490)
0.0 0.8 GO:0006896 Golgi to vacuole transport(GO:0006896)
0.0 0.9 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.0 0.2 GO:0070131 regulation of mitochondrial translation(GO:0070129) positive regulation of mitochondrial translation(GO:0070131)
0.0 0.3 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 0.2 GO:0000012 single strand break repair(GO:0000012)
0.0 0.4 GO:0035677 posterior lateral line neuromast hair cell development(GO:0035677)
0.0 1.1 GO:0016601 Rac protein signal transduction(GO:0016601)
0.0 1.1 GO:0007568 aging(GO:0007568)
0.0 0.8 GO:0050796 regulation of insulin secretion(GO:0050796)
0.0 0.3 GO:1902038 positive regulation of hematopoietic stem cell differentiation(GO:1902038)
0.0 1.3 GO:0006892 post-Golgi vesicle-mediated transport(GO:0006892)
0.0 1.2 GO:0003094 glomerular filtration(GO:0003094)
0.0 0.2 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.0 0.3 GO:0097345 mitochondrial outer membrane permeabilization(GO:0097345)
0.0 0.3 GO:0007096 regulation of exit from mitosis(GO:0007096)
0.0 0.9 GO:0006884 cell volume homeostasis(GO:0006884)
0.0 1.1 GO:0002183 cytoplasmic translational initiation(GO:0002183)
0.0 0.2 GO:0046685 response to arsenic-containing substance(GO:0046685)
0.0 0.7 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.0 0.9 GO:0048263 determination of dorsal identity(GO:0048263)
0.0 0.5 GO:0061154 endothelial tube morphogenesis(GO:0061154) blood vessel lumenization(GO:0072554)
0.0 0.1 GO:0010828 positive regulation of glucose transport(GO:0010828)
0.0 0.8 GO:0006879 cellular iron ion homeostasis(GO:0006879)
0.0 0.5 GO:0043687 post-translational protein modification(GO:0043687)
0.0 0.6 GO:0071427 mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.0 0.1 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.0 0.2 GO:0046958 nonassociative learning(GO:0046958) habituation(GO:0046959)
0.0 0.2 GO:0006515 misfolded or incompletely synthesized protein catabolic process(GO:0006515)
0.0 0.4 GO:2001243 negative regulation of intrinsic apoptotic signaling pathway(GO:2001243)
0.0 0.2 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 0.8 GO:0006360 transcription from RNA polymerase I promoter(GO:0006360)
0.0 0.3 GO:0030210 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.0 0.4 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.2 GO:0060976 coronary vasculature development(GO:0060976)
0.0 0.9 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.1 GO:0043111 replication fork arrest(GO:0043111)
0.0 0.2 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.1 GO:0048014 Tie signaling pathway(GO:0048014)
0.0 0.8 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 0.1 GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.0 0.1 GO:0021961 posterior commissure morphogenesis(GO:0021961)
0.0 0.2 GO:0071376 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.0 0.2 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.0 0.2 GO:0086091 regulation of heart rate by cardiac conduction(GO:0086091)
0.0 1.1 GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage(GO:0008630)
0.0 0.2 GO:0031998 regulation of fatty acid beta-oxidation(GO:0031998)
0.0 0.3 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.0 0.1 GO:0015743 thiosulfate transport(GO:0015709) oxaloacetate transport(GO:0015729) malate transport(GO:0015743) succinate transport(GO:0015744) succinate transmembrane transport(GO:0071422) malate transmembrane transport(GO:0071423)
0.0 0.2 GO:0043697 dedifferentiation(GO:0043696) cell dedifferentiation(GO:0043697)
0.0 0.1 GO:0006622 protein targeting to lysosome(GO:0006622)
0.0 0.9 GO:0042752 regulation of circadian rhythm(GO:0042752)
0.0 0.5 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.1 GO:0045745 positive regulation of G-protein coupled receptor protein signaling pathway(GO:0045745)
0.0 1.0 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.1 GO:0000390 spliceosomal complex disassembly(GO:0000390)
0.0 0.1 GO:2001287 optomotor response(GO:0071632) caveolin-mediated endocytosis(GO:0072584) negative regulation of clathrin-mediated endocytosis(GO:1900186) regulation of caveolin-mediated endocytosis(GO:2001286) negative regulation of caveolin-mediated endocytosis(GO:2001287)
0.0 0.0 GO:2000425 regulation of apoptotic cell clearance(GO:2000425)
0.0 0.2 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.3 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.1 GO:0021794 thalamus development(GO:0021794)
0.0 0.1 GO:1903232 melanosome assembly(GO:1903232)
0.0 1.8 GO:0034976 response to endoplasmic reticulum stress(GO:0034976)
0.0 0.2 GO:0006490 oligosaccharide-lipid intermediate biosynthetic process(GO:0006490)
0.0 1.6 GO:0030178 negative regulation of Wnt signaling pathway(GO:0030178)
0.0 0.6 GO:0014046 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.0 0.1 GO:2001242 regulation of intrinsic apoptotic signaling pathway(GO:2001242)
0.0 0.2 GO:0016926 protein desumoylation(GO:0016926)
0.0 0.4 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.0 GO:0001774 microglial cell activation(GO:0001774)
0.0 0.1 GO:0031063 regulation of histone deacetylation(GO:0031063)
0.0 0.2 GO:0045740 positive regulation of DNA replication(GO:0045740)
0.0 0.4 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0 0.3 GO:0021551 central nervous system morphogenesis(GO:0021551)
0.0 0.3 GO:0022011 myelination in peripheral nervous system(GO:0022011)
0.0 1.5 GO:0008033 tRNA processing(GO:0008033)
0.0 0.4 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436) positive regulation of proteasomal protein catabolic process(GO:1901800)
0.0 0.4 GO:0014866 skeletal myofibril assembly(GO:0014866)
0.0 0.4 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.3 GO:0008214 protein demethylation(GO:0006482) protein dealkylation(GO:0008214)
0.0 0.9 GO:0006006 glucose metabolic process(GO:0006006)
0.0 0.3 GO:0071216 cellular response to biotic stimulus(GO:0071216) cellular response to molecule of bacterial origin(GO:0071219) cellular response to lipopolysaccharide(GO:0071222)
0.0 0.5 GO:0007019 microtubule depolymerization(GO:0007019)
0.0 0.2 GO:0007020 microtubule nucleation(GO:0007020)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.4 GO:0005787 signal peptidase complex(GO:0005787)
0.4 1.1 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.3 0.8 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.3 0.8 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.2 1.2 GO:0097433 dense body(GO:0097433)
0.2 1.3 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.2 0.6 GO:0070578 RISC-loading complex(GO:0070578)
0.2 0.5 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.2 1.1 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.2 0.5 GO:0034709 methylosome(GO:0034709)
0.1 0.9 GO:0030891 VCB complex(GO:0030891)
0.1 0.5 GO:0097524 sperm plasma membrane(GO:0097524)
0.1 0.8 GO:0000938 GARP complex(GO:0000938)
0.1 1.0 GO:0031616 spindle pole centrosome(GO:0031616)
0.1 0.5 GO:1904423 dehydrodolichyl diphosphate synthase complex(GO:1904423)
0.1 0.6 GO:0070390 transcription export complex 2(GO:0070390)
0.1 4.2 GO:0000421 autophagosome membrane(GO:0000421)
0.1 1.3 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.1 0.5 GO:0033553 rDNA heterochromatin(GO:0033553)
0.1 1.1 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.1 0.6 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.1 0.3 GO:1990072 TRAPPIII protein complex(GO:1990072)
0.1 0.9 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.1 0.4 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.1 0.3 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.1 0.6 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.1 0.2 GO:0008275 gamma-tubulin small complex(GO:0008275)
0.1 0.2 GO:0031251 PAN complex(GO:0031251)
0.1 0.6 GO:0001772 immunological synapse(GO:0001772)
0.1 0.4 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.1 1.5 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.1 0.8 GO:0017119 Golgi transport complex(GO:0017119)
0.1 0.2 GO:1990879 CST complex(GO:1990879)
0.1 0.3 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.1 1.1 GO:0030131 clathrin adaptor complex(GO:0030131)
0.1 0.4 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.1 0.7 GO:0044295 axonal growth cone(GO:0044295)
0.1 0.4 GO:0016586 RSC complex(GO:0016586)
0.1 0.2 GO:0034715 pICln-Sm protein complex(GO:0034715)
0.1 0.6 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.8 GO:0005838 proteasome regulatory particle(GO:0005838)
0.0 0.5 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.3 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.0 0.7 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.3 GO:0070847 core mediator complex(GO:0070847)
0.0 0.3 GO:0000439 core TFIIH complex(GO:0000439)
0.0 0.4 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.2 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.4 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.1 GO:0098574 cytoplasmic side of lysosomal membrane(GO:0098574)
0.0 0.2 GO:0005663 DNA replication factor C complex(GO:0005663)
0.0 0.9 GO:0032040 small-subunit processome(GO:0032040)
0.0 1.2 GO:0005758 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.0 0.7 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.9 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 0.1 GO:0031298 replication fork protection complex(GO:0031298)
0.0 0.6 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.3 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.3 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.3 GO:0098827 endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827)
0.0 3.4 GO:0005769 early endosome(GO:0005769)
0.0 0.2 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 1.0 GO:0005902 microvillus(GO:0005902)
0.0 0.3 GO:0005903 brush border(GO:0005903)
0.0 1.1 GO:0001726 ruffle(GO:0001726)
0.0 3.2 GO:0005764 lysosome(GO:0005764)
0.0 0.2 GO:0044545 NSL complex(GO:0044545)
0.0 0.1 GO:0031085 BLOC-3 complex(GO:0031085)
0.0 0.2 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.1 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.0 GO:0032044 DSIF complex(GO:0032044)
0.0 0.6 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 1.2 GO:0016324 apical plasma membrane(GO:0016324)
0.0 0.1 GO:0032021 NELF complex(GO:0032021)
0.0 0.6 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 1.3 GO:0043197 dendritic spine(GO:0043197) neuron spine(GO:0044309)
0.0 1.0 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.4 GO:0016605 PML body(GO:0016605)
0.0 0.1 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 21.4 GO:0005576 extracellular region(GO:0005576)
0.0 0.5 GO:0031941 filamentous actin(GO:0031941)
0.0 0.6 GO:0032592 integral component of mitochondrial membrane(GO:0032592)
0.0 0.0 GO:0019815 B cell receptor complex(GO:0019815)
0.0 0.1 GO:0005922 connexon complex(GO:0005922)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.4 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.4 1.1 GO:0003978 UDP-glucose 4-epimerase activity(GO:0003978)
0.4 1.1 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.3 5.2 GO:0031729 CCR1 chemokine receptor binding(GO:0031726) CCR4 chemokine receptor binding(GO:0031729)
0.2 1.2 GO:0098973 structural constituent of postsynaptic actin cytoskeleton(GO:0098973)
0.2 0.7 GO:0019777 Atg12 transferase activity(GO:0019777)
0.2 0.6 GO:0004377 GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity(GO:0004377)
0.2 0.8 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
0.2 1.0 GO:0060182 apelin receptor activity(GO:0060182)
0.2 1.0 GO:0004645 phosphorylase activity(GO:0004645) glycogen phosphorylase activity(GO:0008184)
0.2 0.6 GO:0043878 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity(GO:0043878)
0.2 5.8 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.2 2.7 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.2 0.8 GO:0001735 prenylcysteine oxidase activity(GO:0001735)
0.2 0.5 GO:0002094 polyprenyltransferase activity(GO:0002094)
0.2 0.7 GO:0042609 CD4 receptor binding(GO:0042609)
0.2 1.1 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.2 1.0 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.2 1.6 GO:0035198 miRNA binding(GO:0035198)
0.1 0.9 GO:0061133 endopeptidase activator activity(GO:0061133)
0.1 1.0 GO:0015189 L-lysine transmembrane transporter activity(GO:0015189)
0.1 0.4 GO:0000996 core DNA-dependent RNA polymerase binding promoter specificity activity(GO:0000996) mitochondrial RNA polymerase binding promoter specificity activity(GO:0034246)
0.1 0.7 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.1 0.7 GO:0016531 copper chaperone activity(GO:0016531)
0.1 0.9 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.1 0.4 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.1 0.4 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086)
0.1 0.4 GO:0004557 alpha-galactosidase activity(GO:0004557)
0.1 0.6 GO:0019865 IgE binding(GO:0019863) immunoglobulin binding(GO:0019865)
0.1 0.9 GO:0005402 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402) sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.1 0.4 GO:0035516 oxidative DNA demethylase activity(GO:0035516) DNA-N1-methyladenine dioxygenase activity(GO:0043734) RNA N6-methyladenosine dioxygenase activity(GO:1990931)
0.1 0.2 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
0.1 2.3 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1 1.0 GO:0003834 beta-carotene 15,15'-monooxygenase activity(GO:0003834) carotenoid dioxygenase activity(GO:0010436)
0.1 0.3 GO:0032184 SUMO polymer binding(GO:0032184)
0.1 0.4 GO:0004379 glycylpeptide N-tetradecanoyltransferase activity(GO:0004379)
0.1 0.5 GO:0008126 acetylesterase activity(GO:0008126)
0.1 1.3 GO:0051117 ATPase binding(GO:0051117)
0.1 1.0 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.1 0.3 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.1 1.1 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.1 0.3 GO:0047464 heparosan-N-sulfate-glucuronate 5-epimerase activity(GO:0047464)
0.1 1.8 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.1 2.1 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.1 0.8 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.1 0.4 GO:0070568 guanylyltransferase activity(GO:0070568)
0.1 0.9 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.1 0.7 GO:0016838 carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.1 0.2 GO:0004736 pyruvate carboxylase activity(GO:0004736)
0.1 1.9 GO:0034062 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.1 0.5 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.1 0.7 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.1 0.3 GO:0008486 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.1 0.7 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.1 0.2 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.1 0.2 GO:0004558 alpha-1,4-glucosidase activity(GO:0004558)
0.1 0.2 GO:0004576 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.1 0.2 GO:0047611 acetylspermidine deacetylase activity(GO:0047611)
0.1 1.0 GO:0035497 cAMP response element binding(GO:0035497)
0.1 1.4 GO:0005246 calcium channel regulator activity(GO:0005246)
0.1 0.7 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.1 0.3 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.1 0.4 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.0 0.6 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.0 0.4 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.0 0.3 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.0 0.9 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 1.7 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.3 GO:0005290 L-histidine transmembrane transporter activity(GO:0005290) L-asparagine transmembrane transporter activity(GO:0015182)
0.0 0.1 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.0 0.6 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.0 1.0 GO:0031543 peptidyl-proline dioxygenase activity(GO:0031543)
0.0 0.1 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.0 0.1 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.0 0.2 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.2 GO:0099602 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.0 0.3 GO:0010340 carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
0.0 0.1 GO:0016361 activin receptor activity, type I(GO:0016361)
0.0 0.3 GO:0008296 3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.0 0.2 GO:0070137 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.0 0.2 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.0 0.6 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.4 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.2 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0 0.3 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.2 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.2 GO:0004974 leukotriene receptor activity(GO:0004974)
0.0 0.7 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.0 1.1 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 0.3 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.0 0.7 GO:0042287 MHC protein binding(GO:0042287)
0.0 1.7 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.1 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.0 0.1 GO:0015117 thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131) malate transmembrane transporter activity(GO:0015140)
0.0 0.2 GO:0009378 four-way junction helicase activity(GO:0009378)
0.0 0.2 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 0.9 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.2 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.4 GO:0010181 FMN binding(GO:0010181)
0.0 0.2 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.0 0.3 GO:0061608 nuclear import signal receptor activity(GO:0061608)
0.0 0.6 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 0.9 GO:0044325 ion channel binding(GO:0044325)
0.0 0.1 GO:0070004 cysteine-type exopeptidase activity(GO:0070004)
0.0 0.3 GO:0051371 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.0 0.4 GO:0015377 cation:chloride symporter activity(GO:0015377) potassium:chloride symporter activity(GO:0015379)
0.0 0.1 GO:0034594 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485) phosphatidylinositol trisphosphate phosphatase activity(GO:0034594)
0.0 0.4 GO:0005112 Notch binding(GO:0005112)
0.0 0.6 GO:0008408 3'-5' exonuclease activity(GO:0008408)
0.0 0.5 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.2 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.3 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.1 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.2 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0 0.2 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 1.2 GO:0016779 nucleotidyltransferase activity(GO:0016779)
0.0 0.6 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.7 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.4 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 0.5 GO:0019200 carbohydrate kinase activity(GO:0019200)
0.0 0.2 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.1 GO:0008502 melatonin receptor activity(GO:0008502)
0.0 0.6 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.1 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.1 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.0 GO:0030626 U12 snRNA binding(GO:0030626)
0.0 0.1 GO:0019841 retinol binding(GO:0019841)
0.0 0.5 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.0 GO:0070051 fibrinogen binding(GO:0070051)
0.0 0.4 GO:1904315 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0 0.1 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.0 0.1 GO:0005537 mannose binding(GO:0005537)
0.0 0.2 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.3 GO:0015036 disulfide oxidoreductase activity(GO:0015036)
0.0 0.2 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.4 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1 0.5 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.9 PID ARF 3PATHWAY Arf1 pathway
0.0 0.1 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.5 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.6 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 0.2 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 1.5 PID PLK1 PATHWAY PLK1 signaling events
0.0 1.5 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.4 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.4 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.3 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 0.5 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 0.3 PID MYC PATHWAY C-MYC pathway
0.0 0.1 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.1 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 0.7 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.3 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.4 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 1.2 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 0.4 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.2 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.2 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.3 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.4 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.2 1.2 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.2 2.6 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.1 2.4 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.1 0.7 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.1 0.4 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.1 1.0 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.1 1.0 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.1 0.9 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.1 0.7 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.1 0.9 REACTOME POL SWITCHING Genes involved in Polymerase switching
0.1 0.9 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 2.4 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 1.0 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.9 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 0.6 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS Genes involved in CREB phosphorylation through the activation of Ras
0.0 0.5 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.3 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.3 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.5 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.0 0.6 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 1.9 REACTOME AUTODEGRADATION OF CDH1 BY CDH1 APC C Genes involved in Autodegradation of Cdh1 by Cdh1:APC/C
0.0 0.5 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0 0.1 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 1.0 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.5 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.4 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.8 REACTOME TRANS GOLGI NETWORK VESICLE BUDDING Genes involved in trans-Golgi Network Vesicle Budding
0.0 0.1 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.3 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.4 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.2 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.3 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation